CN115969333A - Flexible high-sensitivity array sensor for pulse diagnosis detection - Google Patents
Flexible high-sensitivity array sensor for pulse diagnosis detection Download PDFInfo
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- CN115969333A CN115969333A CN202310034021.4A CN202310034021A CN115969333A CN 115969333 A CN115969333 A CN 115969333A CN 202310034021 A CN202310034021 A CN 202310034021A CN 115969333 A CN115969333 A CN 115969333A
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Abstract
The invention provides a flexible high-sensitivity array sensor for pulse diagnosis detection, which comprises: a bottom flexible substrate; a plurality of flexible coplanar serpentine interdigital electrodes disposed on the bottom flexible substrate; the bonding packaging layer is arranged at the edge of the bottom layer flexible substrate and is coplanar with the plurality of flexible coplanar snake-shaped interdigital electrodes; a plurality of sensitive layers with micro-column structures, which are arranged on the plurality of flexible coplanar snake-shaped interdigital electrodes; the micropore spacing layer is arranged on the plurality of sensitive layers with the microcolumn structures; and the surface layer packaging layer is arranged on the micropore spacing layer. According to the sensor, the flexible pressure sensing array can be attached to the body surface of a human body in a conformal mode, and pulse information of a patient can be monitored more friendly. The array sensor is arranged near the pulse point, so that the defect that the single-point sensor slides in position in the detection process can be avoided, and more comprehensive pulse diagnosis information can be obtained.
Description
Technical Field
The invention relates to a preparation method of a large-scale flexible pressure sensor for human health and motion detection, belonging to the technical field of front-edge cross manufacturing of flexible electronics and pressure sensors.
Background
The digitization and objectification of the traditional Chinese medicine diagnosis are one of the problems to be solved urgently in the modernization development of the traditional Chinese medicine. Pulse taking is one of the most distinctive disease diagnosis modes in traditional Chinese medicine, and the use of sensor technology to digitize the pulse taking process is of great significance.
Most of the existing pulse wave sensors are single-point rigid probes, the probe area is large, the spatial resolution is low, multipath detection on pulses in a small area is difficult, the pulse width and pulse length factors can not be accurately extracted by accurately simulating traditional Chinese medicine, and the acquired information is limited, so that the effect of accurately diagnosing pulses by imitating the traditional Chinese medicine can not be achieved. The advent of flexible pressure sensing arrays is expected to become an important tool to address this challenge. The flexible pressure sensing array can be attached to the body surface of a human body in a conformal mode, and pulse information of a patient can be monitored more friendly. The array sensor is arranged near the pulse point, so that the defect that the single-point sensor slides in position in the detection process can be avoided, and more comprehensive pulse diagnosis information can be obtained.
Disclosure of Invention
In order to overcome the defects in the prior art, the invention aims to overcome the defects in the prior functional requirements and technologies and provides a flexible high-sensitivity array sensor for pulse diagnosis detection.
In order to solve the above technical problem, the present invention provides a flexible high-sensitivity array sensor for pulse diagnosis detection, comprising:
a bottom flexible substrate;
a plurality of flexible coplanar serpentine interdigital electrodes disposed on the bottom flexible substrate;
the bonding packaging layer is arranged at the edge of the bottom layer flexible substrate and is coplanar with the plurality of flexible coplanar snake-shaped interdigital electrodes;
a plurality of sensitive layers with micro-column structures, which are arranged on the plurality of flexible coplanar snake-shaped interdigital electrodes;
the micropore spacing layer is arranged on the plurality of sensitive layers with the microcolumn structures;
the surface layer packaging layer is arranged on the micropore spacing layer;
in a preferred embodiment: the pulse length and pulse width detection patch for traditional Chinese medicine pulse diagnosis based on an array sensing mechanism is composed of a bottom layer flexible substrate, a plurality of flexible coplanar snake-shaped interdigital electrodes, an adhesion packaging layer, a plurality of sensitive layers with microcolumn structures, a micropore spacing layer and a surface layer packaging layer.
In a preferred embodiment: the array type sensing mechanism-based pulse-taking pulse-length and pulse-width detection patch is characterized by further comprising an annular air bag which is arranged on the array type sensing mechanism-based pulse-length and pulse-width detection patch for traditional Chinese medicine pulse taking.
In a preferred embodiment: the air bag pressure applying device is connected with the annular air bag through the inflation interface and controls the inner pressure of the air bag through the electric device.
In a preferred embodiment: the pulse condition detection device comprises a processor, a communication circuit and a signal acquisition circuit, acquires the output signals of the pulse length and pulse width detection patch based on the traditional Chinese medicine pulse diagnosis of the array sensing mechanism, and performs wireless transmission after preprocessing.
In a preferred embodiment: the pulse condition detection device comprises a multi-channel capacitance acquisition module, is arranged on a flexible substrate, acquires signals by a line scanning method, and is connected to a PC (personal computer) and a mobile phone in a wireless transmission mode.
In a preferred embodiment: the bottom layer flexible substrate comprises one of a plurality of polymers such as Thermoplastic Polyurethane (TPU), polyolefin elastomer, polystyrene elastomer, polyamide elastomer, silicon rubber, styrene block copolymer and the like, and fiber materials such as paper, leather, cloth and the like.
In a preferred embodiment: the area of a single electrode in the plurality of flexible coplanar snake-shaped interdigital electrodes is 0.3mm 2 ～4mm 2 The distance between two adjacent flexible electrodes is 0.1 mm-0.2 mm;
the occupied area of the plurality of flexible coplanar snake-shaped interdigital electrodes is 0.5cm 2 ～20cm 2 ；
The plurality of flexible coplanar serpentine interdigital electrodes present a rectangular shape.
In a preferred embodiment: the doping material of the plurality of sensitive layers with the micro-column structure comprises at least one of a metal material, a carbon material and a conductive polymer.
In a preferred embodiment: and the surface layer packaging layer is packaged by adopting a PI film.
Compared with the prior art, the technical scheme of the invention has the following beneficial effects:
the invention provides a flexible high-sensitivity array sensor for pulse diagnosis detection, wherein a flexible pressure sensing array can be conformally attached to the body surface of a human body, and the pulse information of a patient can be more friendly monitored. The array sensors are arranged near the pulse points, so that the defect that the single-point sensors slide in the detection process can be avoided, and more comprehensive pulse diagnosis information can be obtained.
Drawings
FIG. 1 is a schematic illustration of the layering of a preferred embodiment of the present invention;
fig. 2 is a diagram of a measurement module of a preferred embodiment of the present invention.
Detailed Description
The technical solution in the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention; it is to be understood that the embodiments described are merely exemplary embodiments, rather than exemplary embodiments, and that all other embodiments may be devised by those skilled in the art without departing from the scope of the present invention.
In the description of the present invention, it should be noted that the terms "upper", "lower", "inner", "outer", "top/bottom", and the like indicate orientations or positional relationships based on those shown in the drawings, and are only for convenience of description and simplification of description, but do not indicate or imply that the referred device or element must have a specific orientation, be constructed in a specific orientation, and be operated, and thus should not be construed as limiting the present invention. Furthermore, the terms "first" and "second" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.
In the description of the present invention, it should be noted that, unless otherwise explicitly specified or limited, the terms "mounted," "disposed," "sleeved/connected," "connected," and the like, are used in a broad sense, and for example, "connected" may be a wall-mounted connection, a detachable connection, an integral connection, a mechanical connection, an electrical connection, a direct connection, an indirect connection through an intermediate medium, and a communication between two elements, and those skilled in the art will understand the specific meaning of the terms in the present invention specifically.
Example 1
As shown in fig. 1-2, the flexible high-sensitivity array sensor for pulse-taking detection provided in this embodiment includes a pulse length and pulse width detection patch, an annular air bag, an air bag pressure device, and a pulse condition detection device for pulse-taking in traditional Chinese medicine based on an array sensing mechanism. The traditional Chinese medicine pulse-length and pulse-width detection patch based on the array sensing mechanism comprises a flexible substrate 1, an adhesive packaging layer 3, a plurality of sensitive layers 4 with microcolumn structures, a micropore spacing layer 5 and a surface layer packaging layer 6. The plurality of flexible coplanar serpentine interdigital electrodes 2 comprise a plurality of individual flexible coplanar serpentine interdigital electrodes 2 which are arranged on the bottom layer flexible substrate 1. The bonding packaging layer 3 is arranged at the edge of the bottom layer flexible substrate 1 and is coplanar with the plurality of flexible coplanar snake-shaped interdigital electrodes 2; the sensitive layers 4 with the micro-column structures are arranged on the flexible coplanar snake-shaped interdigital electrodes 2. The microporous spacing layer 5 is arranged on the plurality of sensitive layers 4 with the microcolumn structures. The surface layer packaging layer 6 is arranged on the micropore spacing layer 5.
The bottom layer flexible substrate 1 comprises one of a plurality of polymers such as Thermoplastic Polyurethane (TPU), polyolefin elastomer, polystyrene elastomer, polyamide elastomer, silicon rubber, styrene block copolymer and the like, and fiber materials such as paper, leather, cloth and the like.
The plurality of sensitive layers 4 with the micro-pillar structure are made of metal materials (such as liquid metal, metal particles, and metal nanowires), carbon materials (such as Carbon Black (CB), carbon Nanotubes (CNTs), and graphene), conductive polymers (such as poly (3,4-ethylenedioxythiophene): polystyrene sulfonate (PEDOT: PSS)) and composites of at least one of other materials (such as MOF, MXene) and high polymer elastomers (for example, the bottom layer flexible substrate 1 comprises one of a plurality of polymers such as Thermoplastic Polyurethane (TPU), polyolefin elastomers, polystyrene elastomers, polyamide elastomers, silicone rubber, styrene block copolymer, and the like).
The modification doping of the plurality of sensitive layers 4 with the micro-column structure mainly comprises three steps of sensitive ink preparation, screen printing (or spin coating) and laser etching.
The bonding and packaging layer 3 is a double-sided adhesive tape.
The area of a single electrode in the plurality of flexible coplanar snake-shaped interdigital electrodes 2 is 0.3mm 2 ～4mm 2 And the distance between two adjacent flexible electrodes is 0.1 mm-0.2 mm.
The plurality of flexible coplanar serpentine interdigital electrodes 2 present a rectangular shape.
The occupied area of the plurality of flexible coplanar snake-shaped interdigital electrodes 2 is 0.5cm 2 ～20cm 2 。
The sensitive layers 4 with the microcolumn structures can be aligned to the spacer layer through holes in space, so that the phenomenon that slippage occurs between the electrodes and the sensitive layers 4 in the bending deformation process is avoided.
The annular air bag is arranged on the array sensing mechanism-based pulse length and pulse width detection patch for traditional Chinese medicine pulse diagnosis and is coated by the air bag.
The air bag pressure applying device is connected with the annular air bag through the inflation interface and can control the internal pressure of the air bag through the electric device.
The pulse condition detection device comprises a processor, a communication circuit and a signal acquisition circuit, and is used for acquiring the output signals of the pulse length and pulse width detection patch based on the traditional Chinese medicine pulse diagnosis of the array sensing mechanism, preprocessing and wirelessly transmitting the signals.
The pulse condition detection device comprises a multi-channel capacitance acquisition module, is arranged on a flexible substrate, acquires signals by a line and column scanning method, and can be connected to a PC (personal computer) and a mobile phone in a wireless transmission mode.
In the present embodiment, a two-dimensional nano material boron nitride is selected as a doping material to prepare a plurality of sensitive layers 4 with a micro-column structure. Specifically, the prepared h-BN ionic liquid is added into the prepared TPU solution. The flexible ionic membrane was prepared using screen printing. Finally, the sensitive layer 4 with the micro-column structure is prepared by using a laser etching technology.
In this example the microporous spacer layer 5 is made of a PI material. Specifically, the prepared PI precursor is subjected to spin coating, and a laser is used for etching a hole structure, so that the electrode can be exposed through a micropore.
In this embodiment, the preparation of the plurality of flexible coplanar serpentine interdigital electrodes 2 specifically comprises: firstly, carrying out plasma treatment on the bottom layer flexible substrate 1, then carrying out metal copper film screen printing on the bottom layer flexible substrate 1, and finally completing the preparation of the plurality of flexible coplanar snake-shaped interdigital electrodes 2 by using a laser etching technology.
In the embodiment, a pulse length and pulse width testing method based on a high-precision pressure array sensor is provided.
In this embodiment, the flexible sensing array is designed for the requirement of pulse width and pulse length detection. The designed sensing array is shown in the figure. The arrangement is more compact in the direction perpendicular to the blood vessels and is less dense in the direction along the blood vessels.
In this embodiment, annular bladder pressurization is used, and the bladder pressure is controlled to be in the range of 0 to 300mmHg.
In another aspect of the invention, a pulse detection system is provided, the device comprising the flexible pressure sensor of any of the above embodiments and a processor.
The processor is used for receiving the digital signals sent by the analog-to-digital converter, converting the digital signals into a real-time one-dimensional oscillogram and a dynamic three-dimensional pulse chart, and further outputting the pulse length and the pulse width in the traditional Chinese medicine pulse diagnosis.
The above description is only a preferred embodiment of the present invention, but the design concept of the present invention is not limited thereto, and any person skilled in the art can make insubstantial changes in the technical scope of the present invention within the technical scope of the present invention, and the actions infringe the protection scope of the present invention are included in the present invention.
Claims (10)
1. A flexible high-sensitivity array sensor for pulse diagnosis detection is characterized by comprising:
a bottom flexible substrate;
a plurality of flexible coplanar serpentine interdigital electrodes disposed on the bottom flexible substrate;
the bonding packaging layer is arranged at the edge of the bottom layer flexible substrate and is coplanar with the plurality of flexible coplanar 5-shaped snake-shaped interdigital electrodes;
a plurality of sensitive layers with micro-column structures, which are arranged on the plurality of flexible coplanar snake-shaped interdigital electrodes;
the micropore spacing layer is arranged on the plurality of sensitive layers with the microcolumn structures;
and the surface layer packaging layer is arranged on the micropore spacing layer.
2. The pulse diagnosis oriented flexible high-sensitivity array sensor 0 device of claim 1, wherein: the pulse length and pulse width detection patch for traditional Chinese medicine pulse diagnosis based on an array sensing mechanism is composed of a bottom layer flexible substrate, a plurality of flexible coplanar snake-shaped interdigital electrodes, an adhesion packaging layer, a plurality of sensitive layers with microcolumn structures, a micropore spacing layer and a surface layer packaging layer.
3. The array type sensor of claim 2, which is used for pulse-taking detection and has high flexibility and sensitivity, and is characterized in that: the pulse-width detection patch is characterized by further comprising an annular air bag which is arranged on the pulse-length and pulse-width detection patch based on the array sensing mechanism 5 for traditional Chinese medicine pulse diagnosis.
4. The array sensor of claim 3, wherein the array sensor comprises: the air bag pressure applying device is connected with the annular air bag through the inflation interface and controls the internal pressure of the air bag through the electric device.
5. The pulse diagnosis oriented flexible high-sensitivity array sensor 0 device of claim 4, wherein: the pulse condition detection device comprises a processor, a communication circuit and a signal acquisition circuit, acquires the output signals of the pulse length and pulse width detection patch based on the traditional Chinese medicine pulse diagnosis of the array sensing mechanism, and performs wireless transmission after preprocessing.
6. The array type sensor of claim 5, which is used for pulse-taking detection and has high flexibility and sensitivity, and is characterized in that: the pulse condition detection device comprises a multi-channel capacitance acquisition module, is arranged on a flexible substrate, acquires signals by a line scanning method, and is connected to a PC (personal computer) and a mobile phone in a wireless transmission mode.
7. The array sensor of claim 1, wherein the array sensor comprises: the bottom layer flexible substrate comprises one of a plurality of polymers such as Thermoplastic Polyurethane (TPU), polyolefin elastomer, polystyrene elastomer, polyamide elastomer, silicon rubber, styrene block copolymer and the like, and fiber materials such as paper, leather, cloth and the like.
8. The array type sensor of claim 1, which is used for pulse diagnosis detection and has high flexibility and sensitivity, and is characterized in that: the area of a single electrode in the plurality of flexible coplanar snake-shaped interdigital electrodes is 0.3mm 2 ～4mm 2 The distance between two adjacent flexible electrodes is 0.1 mm-0.2 mm;
the occupied area of the plurality of flexible coplanar snake-shaped interdigital electrodes is 0.5cm 2 ～20cm 2 ；
The plurality of flexible coplanar serpentine interdigital electrodes exhibit a rectangular shape.
9. The array sensor of claim 1, wherein the array sensor comprises: the doping material of the sensitive layers with the micro-column structures comprises at least one of a metal material, a carbon material and a conductive polymer.
10. The array type sensor of claim 1, which is used for pulse diagnosis detection and has high flexibility and sensitivity, and is characterized in that: and the surface layer packaging layer is packaged by adopting a PI film.
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| CN202310034021.4A CN115969333A (en) | 2023-01-10 | 2023-01-10 | Flexible high-sensitivity array sensor for pulse diagnosis detection |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117245681A (en) * | 2023-11-18 | 2023-12-19 | 张家港江苏科技大学产业技术研究院 | Interdigital touch sensing module facing flexible finger |
| CN117705896A (en) * | 2024-02-04 | 2024-03-15 | 西安电子科技大学 | Flexible NO 2 Preparation method of gas sensor and sensor |
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2023
- 2023-01-10 CN CN202310034021.4A patent/CN115969333A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117245681A (en) * | 2023-11-18 | 2023-12-19 | 张家港江苏科技大学产业技术研究院 | Interdigital touch sensing module facing flexible finger |
| CN117245681B (en) * | 2023-11-18 | 2024-01-26 | 张家港江苏科技大学产业技术研究院 | Interdigital touch sensing module facing flexible finger |
| CN117705896A (en) * | 2024-02-04 | 2024-03-15 | 西安电子科技大学 | Flexible NO 2 Preparation method of gas sensor and sensor |
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