CN115969308A - Remote eye examination system based on ultra-wide-angle eye fundus imaging - Google Patents
Remote eye examination system based on ultra-wide-angle eye fundus imaging Download PDFInfo
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Abstract
The invention relates to the technical field of eye examination. The invention relates to a remote eye examination system based on ultra-wide-angle fundus imaging. The system comprises an ultra-wide angle imaging module, an image correction module, an auxiliary examination module and a clinical information recording module; the ultra-wide angle imaging module shoots and images the fundus of the patient; the image correction module adjusts the image information shot by the ultra-wide angle imaging module. When the fundus of a patient is detected, the ultra-wide-angle lens unit images the fundus of the patient by adopting ultra-wide-angle fundus fluorescein angiography, the auxiliary inspection module images the fundus of the patient by adopting non-mydriatic non-contact scanning laser ophthalmoscopes, the imaging of the ultra-wide-angle lens unit is subjected to auxiliary inspection, the imaging of the ultra-wide-angle lens unit and the imaging of the auxiliary inspection module are optimized by the image correction module, medical personnel can perform comparative analysis according to two groups of images, and the ultra-wide-angle fundus fluorescein angiography has a better imaging effect and is clearer in imaging.
Description
Technical Field
The invention relates to the technical field of eye examination, in particular to a remote eye examination system based on ultra-wide-angle fundus imaging.
Background
Retinal diseases are one of the commonly existing serious eye diseases in modern people, can cause visual impairment and even blindness, are clinically common in retinal vascular diseases, infant eye diseases, retinal holes and retinal detachment and the like, mainly appear as ischemia, degeneration, exudation, hemorrhage, retinal holes and the like, mostly involve the periphery, can gradually influence the central retina from the peripheral retina to cause central visual impairment, and because the retinal diseases often involve the peripheral retina and the early clinical manifestations are not obvious, the clinical diagnosis is often missed, although the traditional fundus oculi shooting technology can realize retinal visual imaging, the fundus visual range is very limited, the peripheral retina can not be effectively peeped and recorded, even most of the peripheral retina can not be observed through shooting, however, physicians with abundant experience can observe and evaluate other clinical examinations (such as Goldmann's triple mirror, indirect ophthalmoscope, etc.), which may cause defects in clinical management, monitoring and follow-up of diseases due to variability and drawing difference among observers, especially in modern medical laws and telemedicine times, real-time recording of diseases is especially important, and the fundus visualization range is an important problem to be solved in the conventional technology, although early related research attempts to expand the fundus visualization range to 75 ° by image stitching technology (montage technology) on 7 standard 30 ° visual fields, the technology requires high cooperation of patients with mydriasis and consumes too much time, and has high requirements for medical technicians, and ultra-wide-angle fundus imaging technology (UWFFI), which is a novel technology introduced in recent years, can well solve the above problems, therefore, a remote eye examination system based on ultra-wide angle fundus imaging is proposed.
Disclosure of Invention
The invention aims to provide a remote eye examination system based on ultra-wide-angle fundus imaging so as to solve the problems in the background technology.
In order to achieve the aim, the remote eye examination system based on the ultra-wide-angle fundus imaging is provided, and comprises an ultra-wide-angle imaging module, an image correction module, an auxiliary examination module and a clinical information recording module;
the ultra-wide angle imaging module is used for shooting and imaging the fundus of the patient;
the image correction module adjusts the image information shot by the ultra-wide angle imaging module;
the auxiliary inspection module performs auxiliary inspection on the information of the image correction module;
the clinical information recording module manages and stores the information.
As a further improvement of the technical solution, the ultra-wide-angle imaging module includes an ultra-wide-angle lens unit and an ultra-wide-angle imaging unit;
the ultra-wide-angle lens unit collects fundus images of a patient by adopting ultra-wide-angle fundus fluorescein radiography and transmits information to the ultra-wide-angle imaging unit;
and the ultra-wide angle imaging unit images according to the information of the ultra-wide angle lens unit.
As a further improvement of the technical solution, the image correction module includes an automatic correction unit, a visual contrast adjustment unit, and an image conversion unit;
the automatic correction unit corrects the image in the ultra-wide angle imaging unit;
the visual contrast adjusting unit enhances the visual contrast of the upper part and the lower part of the image in the ultra-wide angle imaging unit;
and the image conversion unit converts the plane image of the ultra-wide angle imaging unit into a three-dimensional projection image according to the image information processed by the automatic correction unit and the visual contrast adjustment unit.
As a further improvement of the technical scheme, the auxiliary inspection module comprises a red-green two-color laser imaging unit, a blue laser imaging unit and an image processing unit;
the red-green two-color laser imaging unit adopts red-green two-color laser to image the retina of the patient;
the blue laser imaging unit adopts blue laser to image the retina of a patient;
the image processing unit processes the images of the red-green two-color laser imaging unit.
As a further improvement of the technical scheme, the red-green two-color laser imaging unit adopts red-green two-color laser to image the retina of the patient according to the following steps:
s1, imaging a retina of a patient by adopting green laser, and highlighting a anterior retina structure and blood vessels thereof;
s2, imaging the retina of the patient by adopting red laser, and highlighting the choroid structure and blood vessels thereof;
and S3, simultaneously feeding back the red laser imaging and the green laser imaging.
As a further improvement of the technical solution, the clinical information recording module includes a clinical information management unit and a clinical information storage unit;
the clinical information management unit is used for sorting images in the image conversion unit, the blue laser imaging unit and the image processing unit;
the clinical information storage unit stores and records the information of the clinical information management unit.
Compared with the prior art, the invention has the beneficial effects that:
1. in this long-range eye system of examining based on ultra wide angle eye ground formation of image, when examining the eye ground to the patient, ultra wide angle lens unit adopts ultra wide angle eye ground fluorescein radiography to form images to the eye ground of patient, supplementary inspection module adopts exempts from mydriasis non-contact scanning laser ophthalmoscope and forms images to the eye ground of patient, carry out supplementary inspection to the formation of image of ultra wide angle lens unit, the image correction module is optimized ultra wide angle lens unit and supplementary inspection module formation of image, medical personnel can carry out contrastive analysis according to two sets of images, and the imaging effect of ultra wide angle eye ground fluorescein radiography is better, it is more clear to form images.
2. In the remote eye examination system based on the ultra-wide-angle fundus imaging, the clinical value and potential advantages of the ultra-wide-angle fundus fluorescein radiography are widely recognized in the current clinic and research, the system is applied to the management work and research of various clinical departments at present, particularly in the fundus disease department and the dioptric department, in recent years, with the development of the modern automation level, the automatic detection, classification and management of diseases are gradually realized, meanwhile, the clinical application of the technology is developed towards portable medical service, in addition, the ultra-wide-angle fundus fluorescein radiography has certain help in the aspect of determining the specificity related to prognosis, and has certain application prospect in clinical treatment strategies such as retina laser and retina laser prediction.
Drawings
FIG. 1 is an overall flow diagram of the present invention;
FIG. 2 is a block flow diagram of an ultra-wide angle imaging module of the present invention;
FIG. 3 is a block diagram of a flow chart of an image correction module according to the present invention;
FIG. 4 is a block flow diagram of an auxiliary inspection module of the present invention;
FIG. 5 is a block flow diagram of a clinical information logging module of the present invention.
The various reference numbers in the figures mean:
1. an ultra-wide angle imaging module;
11. an ultra-wide-angle lens unit; 12. an ultra-wide angle imaging unit;
2. an image correction module;
21. an automatic correction unit; 22. a visual contrast adjusting unit; 23. an image conversion unit;
3. an auxiliary inspection module;
31. a red-green two-color laser imaging unit; 32. a blue laser imaging unit; 33. an image processing unit;
4. a clinical information recording module;
41. a clinical information management unit; 42. a clinical information storage unit.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be obtained by a person skilled in the art without making any creative effort based on the embodiments in the present invention, belong to the protection scope of the present invention.
In the description of the present invention, it is to be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", and the like, indicate orientations or positional relationships based on those shown in the drawings, merely for convenience of description and simplicity of description, and do not indicate or imply that the device or element so referred to must have a particular orientation, be constructed in a particular orientation, and be operated, and thus, are not to be construed as limiting the present invention.
Example 1
Referring to fig. 1 to 5, the present embodiment aims to provide a remote eye examination system based on ultra-wide-angle fundus imaging, which includes an ultra-wide-angle imaging module 1, an image correction module 2, an auxiliary examination module 3, and a clinical information recording module 4;
the ultra-wide angle imaging module 1 shoots and images the fundus of the patient;
the image correction module 2 adjusts the image information shot by the ultra-wide angle imaging module 1;
the auxiliary checking module 3 performs auxiliary checking on the information of the image correction module 2;
the clinical information recording module 4 manages and stores the above information.
The currently common technology for imaging the fundus of a patient is a non-mydriatic non-contact scanning laser ophthalmoscope which increases the fundus imaging range to 200 degrees through a large elliptic lens, but the periphery of an image formed by the technology has obvious nonlinear distortion, which is closely related to the fact that the digital projection of a three-dimensional spherical stereoscopic surface converted into a two-dimensional plane image cannot be completely and accurately realized, and because the asymmetric optical characteristics of the non-mydriatic non-contact scanning laser ophthalmoscope are influenced by factors such as eyelids and eyelash artifacts, the upper and lower imaging and the contrast are more limited, therefore, the ultra-wide angle imaging module 1 comprises an ultra-wide angle lens unit 11 and an ultra-wide angle imaging unit 12;
the ultra-wide-angle lens unit 11 collects fundus images of a patient by adopting ultra-wide-angle fundus fluorescein radiography and transmits information to the ultra-wide-angle imaging unit 12, the ultra-wide-angle fundus fluorescein radiography in the ultra-wide-angle lens unit 11 consists of a bifocal concave elliptic mirror and a confocal scanning laser ophthalmoscope, the ultra-wide-angle imaging system utilizes the point-to-point laser reflection principle of the elliptic mirror and realizes the acquisition of ultra-large fundus visual field ranges of 200 degrees horizontally and 170 degrees vertically under a small pupil by a measuring mode of the center of gravity visual field of eyes, and the ultra-wide-angle imaging of the fundus of the patient is realized;
the ultra-wide angle imaging unit 12 images according to the information of the ultra-wide angle lens unit 11, the ultra-wide angle imaging unit 12 collects a single orthostatic fundus image and can clearly image to a sawtooth edge, the fundus range of the level 220-240 degrees can be reached even by matching with the nose-temporal eye position guidance, the imaging range of the fundus of a patient is further improved, and the visual field is wider.
The image correction module 2 includes an automatic correction unit 21, a visual contrast adjustment unit 22, and an image conversion unit 23;
the automatic correction unit 21 corrects the image in the ultra-wide angle imaging unit 12, the ultra-wide angle imaging unit 12 can also generate image distortion after imaging, and the automatic correction unit 21 corrects the distorted image to avoid the phenomenon of unclear image when the fundus of a patient is diagnosed in the later period;
the visual contrast adjusting unit 22 enhances the visual contrast of the upper and lower parts of the image in the ultra-wide angle imaging unit 12, after the ultra-wide angle imaging unit 12 is imaged, the visual contrast of the upper and lower parts of the image reaches the highest state, and the visual contrast adjusting unit 22 enhances the visual contrast of the upper and lower parts of the image, so that the fundus imaging effect of the patient is improved, and the later diagnosis of the patient is facilitated;
the image conversion unit 23 converts the planar image of the ultra-wide angle imaging unit 12 into a stereoscopic projection image according to the image information processed by the automatic correction unit 21 and the visual contrast adjustment unit 22, after the ultra-wide angle imaging unit 12 performs ultra-wide angle imaging on the fundus of the patient, the automatic correction unit 21 corrects the image of the ultra-wide angle imaging unit 12, the visual contrast adjustment unit 22 enhances the visual contrast of the upper and lower parts of the image, the image conversion unit 23 converts the image processed by the automatic correction unit 21 and the visual contrast adjustment unit 22, converts the planar image into the stereoscopic projection image, and facilitates accurate diagnosis of the patient.
Because the result of the ultra-wide angle fundus fluorescein radiography has errors, the auxiliary examination is carried out by adopting a non-mydriatic non-contact scanning laser ophthalmoscope, and the auxiliary examination module 3 comprises a red-green two-color laser imaging unit 31, a blue laser imaging unit 32 and an image processing unit 33;
the red-green two-color laser imaging unit 31 adopts red-green two-color laser to image the retina of the patient, and overcomes the defect of single color of the traditional acquired image;
the blue laser imaging unit 32 images the retina of the patient by adopting blue laser, and assists in ultra-wide-angle fundus fluorescein radiography in the ultra-wide-angle lens unit 11, so that the color of the radiography is clearer;
the image processing unit 33 processes the image of the red and green two-color laser imaging unit 31, and the non-linear distortion of the periphery of the image of the red and green two-color laser imaging unit 31 is processed because the periphery of the non-mydriatic non-contact scanning laser ophthalmoscope image has non-linear distortion, so that the digital projection of converting a three-dimensional spherical stereo surface into a two-dimensional plane image cannot be completely and accurately realized.
Because the laser wavelength of different colours is different, so observe that the fundus structure also respectively differs, in order to carry out comprehensive inspection to patient's eyes, red green double-colored laser imaging unit 31 adopts red green double-colored laser to carry out the step of formation of image to patient's retina as follows:
s1, imaging the retina of a patient by adopting green laser, and highlighting the structure of the retina and blood vessels of the retina;
s2, imaging the retina of the patient by adopting red laser, and highlighting the choroid structure and blood vessels thereof;
and S3, simultaneously feeding back the red laser imaging and the green laser imaging.
In clinic, the retinal degeneration mainly including the lattice degeneration is a high-risk factor of retinal dehiscence and pore-derived retinal detachment, is related to the myopia degree and the axial length of eyes, is mostly located in peripheral retinas, is easy to miss diagnosis in the conventional routine examination, and is beneficial to clinical management and record storage of patients with retinal diseases without mydriasis through a non-contact scanning laser ophthalmoscope, and the clinical information recording module 4 comprises a clinical information management unit 41 and a clinical information storage unit 42;
the clinical information management unit 41 arranges the images in the image conversion unit 23, the blue laser imaging unit 32 and the image processing unit 33, and arranges the images of the same eyeball of the same patient together, so as to avoid the phenomenon of information confusion in the later period;
the clinical information storage unit 42 stores and records the information of the clinical information management unit 41, so that the information can be directly called for later diagnosis of the patient.
When the fundus of a patient is checked, the ultra-wide-angle lens unit 11 adopts ultra-wide-angle fundus fluorescein radiography to collect the fundus image of the patient, so that the ultra-wide-angle fundus vision range of horizontally collecting 200 degrees and vertically collecting 170 degrees under a small pupil is realized, the ultra-wide-angle imaging unit 12 can clearly image to a sawtooth edge by collecting a single righting fundus image, the fundus range of horizontally collecting 220 degrees to 240 degrees can be even reached by matching with the nose-temporal eye position guide of the ultra-wide-angle imaging unit, the imaging range of the fundus of the patient is further improved, the vision is wider, the automatic correction unit 21 corrects the image obtained by distortion in the ultra-wide-angle imaging unit 12, the visual contrast adjusting unit 22 enhances the upper visual contrast image and the lower visual contrast image of the image in the ultra-wide-angle imaging unit 12, the image conversion unit 23 converts a plane image into a three-dimensional projection image, the display effect of the image in the ultra-wide-angle imaging unit 12 is increased, and in order, the ultra-wide angle eyeground fluorescein radiography is avoided from generating errors, so the ultra-wide angle eyeground fluorescein radiography is assisted by a non-mydriatic non-contact scanning laser ophthalmoscope, wherein a red-green two-color laser imaging unit 31 and a blue laser imaging unit 32 image the eyeground of a patient, an image processing unit 33 processes the image of the red-green two-color laser imaging unit 31 to avoid the non-linear distortion of the periphery of the image, then an automatic correction unit 21 and an image conversion unit 23 process the pictures in the red-green two-color laser imaging unit 31 and the blue laser imaging unit 32, at the moment, medical personnel can carry out contrast analysis through the ultra-wide angle eyeground fluorescein radiography imaging, the non-mydriatic non-contact scanning laser ophthalmoscope imaging and the blue laser eyeground imaging, the comprehensive and clear diagnosis of the eyeground of the patient is convenient, and the clinical information management unit 41 and the clinical information storage unit 42 arrange and store the information, the later stage of being convenient for is transferred fast and is got and watch.
In practical application, the invention comprises the following steps: 1. for diabetic retinopathy evaluation, 7 standard 30-degree visual field fundus stereo images are adopted in the early stage, but imaging by the method can only cover 30% of the whole retina, a mydriasis-free non-contact scanning laser ophthalmoscope image under a single small pupil can present about 80% of the retinal range, the whole visual range is improved by nearly 3 times, the fundus range which can be presented by ultra-wide-angle fundus fluorescein radiography imaging is 3.2 times that of the 7 standard 30-degree visual field fundus stereo images, the observed non-perfusion area, the newly formed blood vessel and the whole retinal photocoagulation range can be respectively increased by 3.9 times, 1.9 times and 3.8 times, and the diabetic retinopathy evaluation by medical staff is facilitated;
2. the retinal degeneration mainly based on the lattice degeneration is a high-risk factor of retinal fissure and pore-originated retinal detachment, is related to the myopia degree of eyes and the length of an ocular axis, is mostly located in peripheral retinas, is easy to miss diagnosis in the conventional examination before, and can effectively reduce the misdiagnosis rate by ultra-wide angle fundus fluorescein radiography imaging; in contrast, if the retina is only slightly elevated or not elevated, the fundus scopy will not be affected, i.e., the non-mydriatic non-contact scanning laser ophthalmoscope can screen retinal tears or light and medium retinal tears and rhegmatogenous retinal detachments for almost all clinical courseware.
The foregoing shows and describes the general principles, essential features, and advantages of the invention. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, and the preferred embodiments of the present invention are described in the above embodiments and the description, and are not intended to limit the present invention. The scope of the invention is defined by the appended claims and equivalents thereof.
Claims (6)
1. Long-range eye system of examining based on super wide angle eye ground formation of image which characterized in that: the system comprises an ultra-wide angle imaging module (1), an image correction module (2), an auxiliary examination module (3) and a clinical information recording module (4);
the ultra-wide angle imaging module (1) is used for shooting and imaging the fundus of a patient;
the image correction module (2) adjusts the image information shot by the ultra-wide angle imaging module (1);
the auxiliary inspection module (3) is used for carrying out auxiliary inspection on the information of the image correction module (2);
the clinical information recording module (4) manages and stores the information.
2. A remote eye examination system based on ultra-wide angle fundus imaging according to claim 1, wherein: the ultra-wide-angle imaging module (1) comprises an ultra-wide-angle lens unit (11) and an ultra-wide-angle imaging unit (12);
the ultra-wide-angle lens unit (11) adopts ultra-wide-angle fundus fluorescein radiography to collect fundus images of a patient and transmits information to the ultra-wide-angle imaging unit (12);
the ultra-wide-angle imaging unit (12) images according to the information of the ultra-wide-angle lens unit (11).
3. A remote eye examination system based on ultra-wide angle fundus imaging according to claim 2, wherein: the image correction module (2) comprises an automatic correction unit (21), a visual contrast adjustment unit (22) and an image conversion unit (23);
the automatic correction unit (21) corrects the image in the ultra-wide angle imaging unit (12);
the visual contrast adjusting unit (22) enhances the visual contrast of the upper part and the lower part of the image in the ultra-wide angle imaging unit (12);
the image conversion unit (23) converts the plane image of the ultra-wide angle imaging unit (12) into a stereoscopic projection image according to the image information processed by the automatic correction unit (21) and the visual contrast adjustment unit (22).
4. The ultra-wide angle fundus imaging-based remote eye examination system of claim 3, wherein: the auxiliary inspection module (3) comprises a red-green two-color laser imaging unit (31), a blue laser imaging unit (32) and an image processing unit (33);
the red-green two-color laser imaging unit (31) adopts red-green two-color laser to image the retina of the patient;
the blue laser imaging unit (32) images the retina of the patient by using blue laser;
the image processing unit (33) processes the image of the red-green two-color laser imaging unit (31).
5. The ultra-wide angle fundus imaging-based remote eye examination system of claim 4, wherein: the red and green two-color laser imaging unit (31) adopts red and green two-color laser to image the retina of the patient, and the steps are as follows:
s1, imaging the retina of a patient by adopting green laser, and highlighting the structure of the retina and blood vessels of the retina;
s2, imaging the retina of the patient by adopting red laser, and highlighting the choroid structure and blood vessels thereof;
and S3, simultaneously feeding back the red laser imaging and the green laser imaging.
6. The ultra-wide angle fundus imaging-based remote eye examination system of claim 4, wherein: the clinical information recording module (4) comprises a clinical information management unit (41) and a clinical information storage unit (42);
the clinical information management unit (41) arranges the images in the image conversion unit (23), the blue laser imaging unit (32) and the image processing unit (33);
the clinical information storage unit (42) stores and records the information of the clinical information management unit (41).
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| CN117649347A (en) * | 2024-01-30 | 2024-03-05 | 宁乡爱尔眼科医院有限公司 | Remote eye examination method and system based on ultra-wide-angle fundus imaging |
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| CN112513999A (en) * | 2017-10-13 | 2021-03-16 | 人工智能技术公司 | Deep learning based diagnosis and referral of ophthalmic diseases and conditions |
| JP2020018713A (en) * | 2018-08-02 | 2020-02-06 | 株式会社ニデック | Fundus imaging apparatus |
| JP2022089086A (en) * | 2020-12-03 | 2022-06-15 | 株式会社ニコン | Image processing method, image processing system, and image processing program |
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| CN117649347A (en) * | 2024-01-30 | 2024-03-05 | 宁乡爱尔眼科医院有限公司 | Remote eye examination method and system based on ultra-wide-angle fundus imaging |
| CN117649347B (en) * | 2024-01-30 | 2024-04-19 | 宁乡爱尔眼科医院有限公司 | Remote eye examination method and system based on ultra-wide-angle fundus imaging |
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