CN115944560B - Body-refreshing lotion and preparation method thereof - Google Patents

Body-refreshing lotion and preparation method thereof Download PDF

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CN115944560B
CN115944560B CN202310234225.2A CN202310234225A CN115944560B CN 115944560 B CN115944560 B CN 115944560B CN 202310234225 A CN202310234225 A CN 202310234225A CN 115944560 B CN115944560 B CN 115944560B
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extract
agents
inci
stirring
silica
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CN115944560A (en
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毛华丽
刘晓钧
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Guangzhou Yuanda Biotechnology Co ltd
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Guangzhou Yuanda Biotechnology Co ltd
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    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
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Abstract

The invention belongs to the field of daily chemicals, and discloses a body-refreshing lotion which comprises the following components in percentage by weight: 3-7% of tapioca starch; 3-7% of modified corn starch; 3-6% of silica; 3-5% of grease; 0.5 to 1.5 percent of emulsifying agent; a proper amount of thickening agent; and the balance of deionized water. The body refreshing lotion adopts a liquid formula, has small powder consumption, exerts the body refreshing performance of the powder extremely, effectively controls the consumption of silica and ensures the safety of the silica. Meanwhile, the invention also provides a preparation method of the body lotion.

Description

Body-refreshing lotion and preparation method thereof
Technical Field
The invention belongs to the field of new daily chemical materials, and particularly relates to a body-refreshing lotion and a preparation method thereof.
Background
CN104622774B discloses a liquid toilet powder for protecting buttocks of infants and a preparation method thereof, the method comprises the following steps: heating water to boil, maintaining for 30min for sterilization, cooling to below 40deg.C, adding xanthan gum, hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer, stirring, and homogenizing; adding sulfonated shale oil, chinese flowering crabapple oil, chitosan oligosaccharide, honey, neodiol 68T and zinc oxide, stirring and homogenizing until uniformity; and finally adding tapioca starch and polymethyl silsesquioxane modified tapioca starch, stirring until the liquid is fine and uniform, and discharging to obtain the infant hip-protecting liquid talcum powder.
CN112754954a discloses a baby corn talcum powder which comprises the following components in percentage by mass: 50% -96% of corn starch; 0.24% -1% of phenoxyethanol; 0.12% -4% of p-hydroxyacetophenone; 0.11% -5% of 1, 2-hexanediol; 2% -10% of silica; 1.5% -15% of zinc oxide; dipotassium glycyrrhizinate 0.01% -5%; 0.01% -5% of magnesium stearate; 0.01% -5% of lauroyl lysine.
CN108434016a discloses a modified corn starch talcum powder and a preparation method thereof, wherein the talcum powder is prepared from the following raw materials in parts by weight: 80-100 parts of modified corn starch, 1-10 parts of zinc oxide, 1-5 parts of silica, 1-5 parts of tricalcium phosphate and 0.01-0.1 part of benzethonium chloride.
CN110742844a discloses a multi-effect talcum powder and a preparation method thereof. The multi-effect talcum powder is mainly prepared from the following components in percentage by weight: 60-80% of modified corn starch, 10-20% of microcrystalline cellulose, 1-10% of tapioca starch, 1-10% of zinc oxide, 1-10% of tricalcium phosphate, 0.2-1% of radix stephaniae tetrandrae extract, 0.5-2% of menthol, 0.5-2% of herba alpine leontopogonis extract, 0.2-1% of oat kernel extract, 0.02-0.1% of tea polyphenol and 0.1-0.5% of tocopheryl acetate. The talcum powder provided by the invention has various effects of removing miliaria, relieving itching, absorbing moisture, refreshing body, sterilizing, calming and the like. In addition, the powder does not contain inorganic minerals such as talcum powder, silica and silicon dioxide which are not easy to metabolize, and the safety is high.
The following can be concluded from the above documents:
1. combinations of starch and silica are widely used in talcum powders;
2. silica has a safety hazard and so starch is preferred.
The technical problem that the present case solves is: how to improve the body refreshing effect of daily chemical products and the safety of the products.
Disclosure of Invention
Aiming at the defects and shortcomings of the prior art, the primary aim of the invention is to provide the body refreshing lotion which adopts a liquid formula, has small powder dosage, exerts the body refreshing performance of the powder extremely, effectively controls the dosage of silica and ensures the safety.
The invention also aims at providing a preparation method of the body lotion.
The invention aims at realizing the following technical scheme:
a body lotion comprises the following components in percentage by weight:
3-7% of tapioca starch;
3-7% of modified corn starch;
3-6% of silica;
3-5% of grease;
0.5 to 1.5 percent of emulsifying agent;
a proper amount of thickening agent;
and the balance of deionized water.
In practical applications, the tapioca starch is selected in an amount of 3%, 3.5%, 4%, 4.5%, 5%, 5.5%, 6%, 6.5% or 7%;
the modified corn starch is optionally present in an amount of 3%, 3.5%, 4%, 4.5%, 5%, 5.5%, 6%, 6.5% or 7%;
the selectable amount of the grease is 3%, 3.5%, 4%, 4.5% or 5%;
the emulsifier is optionally present in an amount of 0.5%, 0.7%, 0.9%, 1.1%, 1.3% or 1.5%;
the thickener is optionally present in an amount of 0.5%, 0.7%, 0.9%, 1.1%, 1.3% or 1.5%;
the body lotion comprises the following components in percentage by weight:
4-6% of tapioca starch;
2-4% of modified corn starch;
4-5% of silica;
3-5% of grease;
0.5 to 1.5 percent of emulsifying agent;
0.5-1.5% of thickener;
and the balance of deionized water.
The body lotion comprises the following components in percentage by weight: 4% of tapioca starch;
3% of modified corn starch;
silica 5%;
3-5% of grease;
0.5 to 1.5 percent of emulsifying agent;
0.5-1.5% of thickener;
and the balance of deionized water.
The body lotion further comprises: humectant: 8-12%; plant extracts: 1-5%.
In the body lotion, the oil is one or more of isononyl isononanoate, jojoba (SIMMONDSIA CHINENSIS) seed oil, camellia (CAMELLIA JAPONICA) seed oil, tocopheryl acetate and butter;
the thickening agent is one or more of hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer;
the emulsifier is one or more of polyglycerol-3 methyl glucose distearate, stearyl alcohol polyether-21, stearyl alcohol polyether-2 and glycerol stearate citric acid ester.
In the body lotion, the humectant is one or more of glycerin, butanediol, panthenol and 1,2 hexanediol;
the plant extract is one or more of flos Chrysanthemi Indici (CHRYSANTHEMUM INDICUM) flower extract, flos Lonicerae (LOUICERA JAPONICA) flower extract, radix et rhizoma Rhei Palmati (Rheum PALMATUM) root extract, flos Matricariae Chamomillae (CHRYSANTHELLUM INDICUM) extract, radix Sophorae Flavescentis (SOPHORA ANGUSTIFOLIA) root extract, and Aloe BARBADENSIS (Aloe bardansis) leaf extract.
As a further preferred aspect of the present invention, the plant extract may be selected from the group consisting of:
for example and without limitation, extracts or hydrolyzed extracts of clematis, centella asiatica, musk roses, echinacea angustifolia, comfrey, equisetum, hypericum perforatum, mimosa, avocado, african thorn plums, marigold, aloe vera, epithelizing [ INCI ] sold by Provital: calendula, hypericum perforatum, matricaria chamomilla, rosmarinus officinalis ], LS 9028 sold by Laboratories S biologs [ INCI: hydrolyzed casein, hydrolyzed yeast protein, lysine hydrochloride ], sold by kelotus/ange [ INCI: corn (corn) kernel extract ] and the like;
in addition, as a preferred aspect of the present invention, the present invention may further incorporate small amounts of other small molecule peptides, salts of various extracts, and available chemical synthesis additives as adjuvants, as follows:
among the cosmetically or pharmaceutically acceptable adjuvants contained in the cosmetic or pharmaceutical compositions described in the present invention are: additional ingredients in compositions typically used for the treatment and/or care of skin and/or mucous membranes, such as, and without limitation, other AQP-3 modulators, aquaporin modulators, proteins from the aquaporin family, agents that stimulate other collagen synthesis, agents that modulate PGC-1 alpha synthesis, agents that modulate ppary activity, agents that increase or decrease the triglyceride content of adipocytes, agents that stimulate or retard adipocyte differentiation, lipolytic or lipolysis-stimulating agents, lipolytic agents, adipogenic agents, inhibitors of acetylcholine receptor aggregation, agents that inhibit muscle contraction, anticholinergic agents, elastase inhibitors, matrix metalloproteinase inhibitors, melanin synthesis stimulation or inhibitors, whitening or decolouring agents, pro-pigmentation agents, self-tanning agents, anti-aging agents, NO-synthase inhibitors, 5 alpha-reductase inhibitors, inhibitors of lysyl hydroxylase and/or prolyl hydroxylase antioxidants, free radical scavengers and/or anti-atmospheric agents, active carbonyl scavengers, anti-glycation agents, antihistamines, antivirals, antiparasitics, emulsifiers, emollients, organic solvents, liquid propellants, skin conditioning agents such as moisturizers, moisture retaining substances, alpha hydroxy acids, beta hydroxy acids, moisturizers, epidermohydrolases, vitamins, amino acids, proteins, pigments or colorants, dyes, biopolymers, gelling polymers, thickeners, surfactants, softeners, adhesives, preservatives, anti-wrinkling agents, agents capable of reducing or treating the lower eye bags, exfoliants, keratolytic agents, antimicrobial agents, antifungal agents, fungistats, sterilizing agents, bacteriostats, agents which stimulate the synthesis of dermal or epidermal macromolecules and/or which inhibit or prevent their degradation, agents which stimulate collagen synthesis, agents which stimulate elastin synthesis, agents which stimulate decorin synthesis, agents which stimulate laminin synthesis, agents which stimulate defensin synthesis, agents which stimulate chaperonin synthesis, agents which stimulate cAMP synthesis, heat shock proteins, agents which stimulate HSP70 synthesis, agents which stimulate heat shock protein synthesis, agents which stimulate hyaluronic acid synthesis, agents which stimulate fibronectin synthesis, agents which stimulate deacetylase synthesis, agents which stimulate the synthesis of lipids and stratum corneum components, ceramides, fatty acids, agents which inhibit collagen degradation, agents which inhibit elastin degradation, agents which inhibit serine proteases such as cathepsin G, agents which stimulate fibroblast proliferation, agents which stimulate keratinocyte proliferation agents that stimulate adipocyte proliferation, agents that stimulate melanocyte proliferation, agents that stimulate keratinocyte differentiation, agents that inhibit acetylcholinesterase, agents that relax skin, agents that stimulate glycosaminoglycan synthesis, anti-hyperkeratosis agents, acne solubilizers, anti-psoriasis agents, anti-dermatitis agents, anti-eczema agents, DNA repair agents, DNA protectants, stabilizers, antipruritics, agents for treating and/or caring for sensitive skin, solidifying agents, tightening agents, restructuring agents, stretch-proofing agents, adhesives, agents that regulate sebum production, antiperspirant agents, agents that stimulate healing, agents that assist healing, agents that stimulate re-epithelialization, agents that assist re-epithelialization, cytokine growth factors, sedatives, anti-inflammatory agents, anesthetics, agents that act on capillary circulation and/or microcirculation, agents that stimulate angiogenesis, agents that inhibit vascular permeability, venous tonicity agents (venotonic agents), agents acting on cellular metabolism, agents for improving dermal-epidermal junction, agents inducing hair growth, hair growth inhibitors or retarders, fragrances, perfumes, chelating agents, plant extracts, essential oils, marine extracts, agents derived from biological fermentation processes, inorganic salts, cellular extracts, sunscreens, and organic or inorganic photoprotective agents effective against a and/or B ultraviolet light, or mixtures thereof, provided that they are physically and chemically compatible with the remaining components of the composition and in particular with the ingredients contained in the compositions of the invention. Also, the nature of these additional ingredients should not unacceptably alter the benefits of the various ingredient combinations of the invention. The nature of these additional components may be synthetic or natural such as plant extracts, or from a biotechnological process, or from a combination of a synthetic and a biotechnological process. Additional examples can be found in "CTFA international cosmetic ingredients dictionary and Handbook (CTFA International Cosmetic Ingredient Dictionary & Handbook)", 12 th edition (2008). In the context of the present invention, a biotechnological process is understood to be any process for the production of the active ingredient, or a part of the active ingredient, in an organism, or a part of an organism.
Furthermore, the present invention may further comprise a cosmetically or pharmaceutically effective amount of at least one compound, oil or wax selected from the group consisting of cosmetic or pharmaceutical adjuvants, the group formed by: humectants, moisture-retaining materials, humectants, and emollients, such as, but not limited to, polyols and polyethers such as glycerol, ethylhexyl glycerol, octyl glycol, pentyl glycol, butyl glycol, propylene glycol and its derivatives, triethylene glycol, polyethylene glycol, glycerol polyether-26 (glyceth-26), sorbitol polyether-30 (Sorbeth-30); panthenol; pyroglutamic acid and salts or derivatives thereof; amino acids such as serine, proline, alanine, glutamic acid, or arginine; ectoin (ectoin) and derivatives thereof; n- (2-hydroxyethyl) acetamide; pyrrolidone Carboxylic Acid (PCA); n-lauroyl-pyrrolidone carboxylic acid; N-lauroyl-L-lysine; n- α -benzoyl-L-arginine; urea; creatine; alpha-and beta-hydroxy acids such as lactic acid, glycolic acid, malic acid, citric acid, tartaric acid, or salicylic acid, and salts thereof; polyglycerol acrylate (polyglyceryl acrilate); sugars and polysaccharides such as glucose, isomerate sugars (isomerate saccharide), sorbitol, pentaerythritol, inositol, xylitol, sorbitol, trehalose and derivatives thereof, sodium glucuronate, carrageenan (carrageenans) or chitosan; glycosaminoglycans such as hyaluronic acid and derivatives thereof; aloe vera in any form; honey; soluble collagen; lecithin and phosphatidylcholine; a ceramide; cholesterol and esters thereof; tocopherols and esters thereof, such as tocopheryl acetate or tocopheryl linoleate; long chain alcohols such as cetostearyl alcohol, stearyl alcohol, cetyl alcohol, oleyl alcohol, isocetyl alcohol, or stearyl-2-ol; long chain alcohol esters such as lauroyl lactylate, myristoyl acetate or C 12 -C 15 Alkyl benzoates; fatty acids such as stearic acid, isostearic acid or palmitic acid; polyunsaturated fatty acids (PUFAs); sorbitan such as sorbitan distearate; glycerides such as glyceryl monoricinoleate, glyceryl monostearateOil esters, glyceryl stearate citrate, or caprylic and capric triglycerides; sucrose esters such as sucrose palmitate or sucrose oleate; butylene glycol esters, such as dicaprylate and dicaprate; fatty acid esters such as isopropyl isostearate, isobutyl palmitate, isocetyl stearate, isopropyl laurate, hexyl laurate, decyl oleate, cetyl palmitate, di-n-butyl sebacate, isopropyl myristate, isopropyl palmitate, isopropyl stearate, butyl myristate, isopropyl linoleate, 2-ethylhexyl palmitate, 2-ethylhexyl cocoate, decyl oleate, myristyl myristate; squalene (squarene); mink oil (mink oil); lanolin and its derivatives; acetylated lanolin alcohol; silicone derivatives such as cyclomethicone (cyclomethicone), dimethicone (dimethicone) or dimethicone; INCI sold by Li Putai company (Lipotec): pseudomonas fermentation extract]、Xpertmoist TM [ INCI: glycerol, pseudoalteromonas fermentation extract, xanthan gum, proline, alanine, serine, ethylhexyl glycerol, caprylic glycol]、Bodyfensine TM [ INCI: acetyl dipeptide-3 aminocaproic acid ester]Or Hyadisine TM [ INCI: pseudomonas fermentation extract]The method comprises the steps of carrying out a first treatment on the surface of the Petrolatum; mineral oil; mineral waxes and synthetic waxes; beeswax (white beeswax); paraffin wax; or waxes or oils of vegetable origin such as candelilla (candelilla), carnauba (carnauba), shea butter (shea), cocoa butter (cocoa), castor oil (castor), sunflower seed oil (sunflower), olive oil (olive), coconut oil (coconut), palm oil (oil palm), wheat germ oil (wheat germ), sweet almond oil (sweet almond), musk rose seed oil (musk rose), wild soybean oil (wild soybean), grape seed oil (grape), calendula oil (calendula), jojoba oil (jojoba family), mango oil (mango), avocado oil (avocado), and the like, and/or mixtures thereof.
The present invention may also comprise a cosmetic or pharmaceutical composition of at least one anti-wrinkle and/or anti-aging agent selected from, but not limited to, the group consisting of: grape, dog rose, turmeric, cocoa, ginkgo, alpine leontopodium herb,Or an extract or hydrolyzed extract of dunaliella salina, etc., or at least one synthetic compound or product of biotechnological origin, which is an anti-wrinkle and/or anti-aging agent, such as, and without limitation, [ INCI, sold by sedama (Sederma)/cereal (Croda): palmitoyl pentapeptide-4]Matrixyl [ INCI: palmitoyl tetrapeptide-7, palmitoyl oligopeptides]、Essenskin TM [ INCI: calcium hydroxy methionine]Renovage [ INCI: teprenone]Or [ INCI: palmitoyl oligopeptides]The [ INCI ] sold by Pan Defa (Pentaparm)/Dissman (DSM): pentapeptide 3][ INCI: dipeptide diamino Ding Xianbian-yl amide diacetate][ INCI: palmitoyl tripeptide-5]Phytaluronate [ INCI: locust bean (Ceratoniasiiqua) gum]Or [ INCI: wild soybean (soybean) protein and oxidoreductase]Myoxinol sold by (laboratories) Rerobiologiques/Corning (Cognis) TM [ INCI: hydrolyzed Abelmoschus esculentus (Hibiscus esculentus) extract]、Syniorage TM [ INCI: acetyl tetrapeptide-11]、Dermican TM [ INCI: acetyl tetrapeptide-9]Or DN AGE TM LS [ INCI: extract of leaves of Cassia ptera (Cassia alata)]Algisum [ INCI ] sold by Aizimex (Exsymol): methylsilanol mannuronate]Or a hydroxoxyproprisilane [ INCI: methylsilanol hydroxyproline ester aspartate]INCI sold by Lu Borun (Lipotec): acetyl hexapeptide-8]SNAP-7[ inci: acetyl heptapeptide-4]SNAP-8[ inci: acetyl octapeptide-3][ INCI: pentapeptide-18]、Inyline TM [ INCI: acetyl hexapeptide-30][ INCI: hydrolyzed wheat protein, hydrolyzed soybean protein, tripeptide 1]、Preventhelia TM [ INCI: diaminopropionyl tripeptide-33][ INCI: tripeptide-10 citrulline][ INCI: pseudomonas fermented extract, hydrolyzed wheat protein, hydrolyzed soybean protein, tripeptide 10 citrulline, tripeptide 1][ INCI: acetyl tetrapeptide-5]PeptideAC 29[ INCI: acetyl tripeptide-30 citrulline]、Relistase TM [ INCI: acetyl arginyl primary aminoacyl diphenylglycine][ INCI: acetyl tetrapeptide-22]Lipochroman 6[ inci: dimethylmethoxychromanol]、Chromabright TM [ INCI: dimethyl methoxy palmitic acid chromogen ester][ INCI: pseudomonas fermentation extract]、dGlyage TM [ INCI: lysine hydrochloride, lecithin, tripeptide-9 citrulline]、Vilastene TM [ INCI: lysine hydrochloride, lecithin, tripeptide-10 citrulline]Or Hyadisine TM [ INCI: pseudomonas fermentation extract]An [ INCI ] sold by European molecular biology laboratory (Institut Europeen de Biologie Cellulaire): tripeptide 1, dextran]IS [ INCI ] sold by Wen Sensi/international specialty in the united states (Vincience/ISP): hexapeptide-9]、Laminixyl IS TM [ INCI: heptapeptides]、Orsirtine TM GL [ INCI: rice (rice) extract]、D’Orientine TM IS [ INCI: date seed extract]、Phytoquintescine TM [ INCI: single grain wheat (one grain wheat) extract]Or Quintescine TM IS [ INCI: dipeptide-4]BONT-L-Peptide sold by Infinitec Activos [ INCI: palmitoyl hexapeptide-19]Deepaline sold by Sibirch (Seppic) TM PVB [ INCI: palmitoyl hydrolyzed wheat protein]Or DPHP [ INCI: dipalmitoyl hydroxyproline]Expression [ INCI ] sold by Jia Law lion (Gattefosse): extract of button of gold]In-term [ INCI: extract of golden button flower]Or Age Defence 2[ INCI: walnut (Walnut) seed extract]Thalassine sold by Bieuter (Biotechmarine) TM [ INCI: seaweed extract]Chromoline sold by Atrium Innovations/Unipex Group TM [ INCI: caproyl tetrapeptide-3]Or Thymulen-4[ INCI: acetyl tetrapeptide-2]Equistat [ INCI ] sold by Kelotus/Anger/Basff (Coletica/Engelhard/BASF): apple fruit extract, wild soybean seed extract]Or juvenisce [ INCI: ethoxy glycol and caprylic triglyceride, oleum Pini, ursolic acid, phytomenadione, ilomastat]Ameliox [ INCI ] sold by milbac biochemistry company (Mibelle Biochemistry): carnosine, tocopherol, silybum marianum fruit extract]Or PhytoCellTec Malus Domestica [ INCI: apple fruit cell culture]Bioxilift [ INCI, sold by Silab: pimpinella extract]Or SMS [ INCI: annona squamosa seed extract];Ca 2+ Antagonists of the channels such as, but not limited to, alverine, manganese or magnesium salts, certain secondary or tertiary amines, rosin oils and derivatives thereof, idebenone and derivatives thereof, coenzyme Q10 and derivatives thereofA substance, boswellic acid and its derivatives, GHK and its derivatives and/or salts, carnosine and its derivatives; DNA repair enzymes such as, but not limited to, photo-lyase or T4 endonuclease V; or chloride channel agonists, and the like, and/or mixtures thereof.
The present invention may also comprise at least one AQP-3 modulator such as, but not limited to, extracts or hydrolyzed extracts of punica granatum, ajuga sinkiana, centella asiatica, phellodendron amurense, brazil nut, ginseng, glyceryl glycosides, hexosyl glycerides and/or (hexosyl) hexosyl glycerides; cyclic AMP analogs; PKA- (adenylate cyclase) activators; phosphodiesterase inhibitors such as, but not limited to, caffeine or theophylline, inorganic salts such as alkaline earth metal salts, alkali metal salts containing chloride, sulfate, bisulfate, phosphate, hydrogen phosphate, linear or cyclic oligomeric phosphate, carbonate or bicarbonate anions, in particular sodium chloride, sodium bromide, sodium iodide, borax, sodium silicate, sodium carbonate, sodium phosphate, disodium hydrogen phosphate, sodium dihydrogen phosphate, potassium chloride, potassium iodide, lithium chloride, ammonium chloride, zinc chloride, aluminum sulfite, magnesium chloride, magnesium sulfate, salts derived from skin such as sodium lipoic acid (sodium lipoate), sodium citrate, ammonium lactate, sodium bicarbonate, ammonium citrate, sodium propionate; monosaccharides up to 600g/mol, such as, and without limitation, sorbitol, mannitol, sucrose, glucose; amino acids such as, but not limited to, asparagine, glycine, alanine, vitamin a and esters thereof, particularly vitamin a palmitate and acetate; vitamin E and its esters, in particular vitamin E palmitate and acetate; vitamin C and its derivatives, in particular magnesium ascorbyl phosphate; xanthines, in particular caffeine; asiatic acid, madecassoside, ellagic acid, soyasaponin, pure seawater, magnesium aspartate, manganese chloride, cyclic AMP, D-xylose, hyaluronic acid, calcium gluconate, isoflavone, ammonium glycyrrhizate, corticosteroids, resveratrol or peptides, etc., and/or mixtures thereof.
In addition, the present invention may also comprise at least one healing-stimulating agent, healing-assisting agent and/or re-epithelizing agent, such as, and not limited to, iron wireExtracts or hydrolyzed extracts of lotus, centella asiatica, musk roses, echinacea angustifolia, comfrey, equisetum, hypericum perforatum, mimosa, avocado, prune africana, marigold, aloe vera, and the epighezing [ INCI ] sold by baonhead (provitals): calendula, hypericum perforatum, chamomile and rosemary]LS 9028 sold by Laboratories S e robiologues [ INCI: hydrolyzed casein, hydrolyzed yeast protein, lysine hydrochloride]INCI sold by Kelian/Ange: semen Maydis (semen Maydis) extract]Etc.; and/or a cosmetically or pharmaceutically effective amount of at least one synthetic compound, extract or product from a biotechnology process that is a healing-stimulating agent, healing-assisting agent and/or re-epithelizing agent, such as, and without limitation, allantoin, cadherin, integrins, selectins, hyaluronan receptors, immunoglobulins, fibroblast growth factor, connective tissue growth factor, platelet-derived growth factor, vascular endothelial growth factor, epidermal growth factor, insulin-like growth factor, keratinocyte growth factor, colony stimulating factor, transforming growth factor β, tumor necrosis factor α, interferon, interleukins, matrix metalloproteinases, protein tyrosine phosphatase receptors, [ INCI ] sold by Li Putai company: pseudomonas fermentation extract][ INCI: acetyl dipeptide-3 aminocaproic acid ester]Or Decorinyl TM [ INCI: tripeptide 10 citrulline][ INCI: pseudomonas fermented extract, hydrolyzed wheat protein, hydrolyzed soybean protein, tripeptide-10 citrulline, tripeptide-1]、Xpertmoist TM [ INCI: glycerol, pseudoalteromonas fermentation extract, xanthan gum, proline, alanine, serine, ethylhexyl glycerol, caprylic glycol][ INCI: hexapeptide-10]Or thermostreessine TM [ INCI: acetyl tetrapeptide-22]And/or mixtures thereof.
The present invention may also comprise at least one anti-psoriasis, anti-dermatitis and/or anti-rash agent, such as, and without limitation, corticosteroids such as clobetasol (clobetasol), betamethasone, dexamethasone, halobetasol, diflorasone, fluocinolone acetonide, halcinonide, ambetanide, dexamethasone, triamcinolone acetonide, mometasone, fluticasone, fluocinolone acetonide, fludrolide, budesonide, prednisolide, hydrocortisone, calcipotriol, vitamin D, anthralin, calcitriol, salicylic acid; coal tar, derivatives and byproducts of the coal industry; petroleum fractionated tars, derivatives and byproducts, tazarotene, antibiotics, azathioprine, colchicine, 5-fluorouracil, fumarate, hydroxyurea, mycophenolate mofetil, propylthiouracil, sulfasalazine, 6-thioguanine, calcineurin inhibitors, such as, and not limited to, tacrolimus and pimecrolimus; or topically applied retinoids such as, but not exclusively, retinoic acid, and the like, and/or mixtures thereof.
Meanwhile, the invention also discloses a preparation method of the body lotion, which comprises the following steps:
step 1: deionized water, an emulsifying agent, grease and a thickening agent are prepared into emulsion;
step 2: adding tapioca starch, modified corn starch and silica into the emulsion, and stirring and mixing to obtain body refreshing lotion;
compared with the prior art, the invention has the beneficial effects that:
the formula of the invention has the functions of relieving miliaria, drying and moistening skin, the oil-soluble raw materials and the water-soluble raw materials are emulsified into uniform liquid by the emulsifying agent, three uniformly mixed powders are added according to the proportion, the uniform emulsified liquid wraps the powders in the powder, and the capsule structure of the raw materials such as shell grease, humectant and the like and the powder in the middle is formed.
The three kinds of powder are optimized, so that the optimal body refreshing effect can be achieved.
Drawings
Fig. 1 to 15 of the present invention show the results of the body-refreshing effect test of the blank group, the example, and the comparative example of the present invention.
Detailed Description
The present invention will be described in further detail with reference to examples, but embodiments of the present invention are not limited thereto.
The suppliers and types of the main raw materials of the invention are as follows:
hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer: the supplier Guangzhou market Bai Hao Co., ltd; brand SEPINOV WEO;
jojoba (SIMMONDSIA CHINENSIS) seed oil: vendor Guangzhou He vast Biotechnology Co., ltd; brand JD Jojoba Golden Oil;
camellia (CAMELLIA JAPONICA) seed oil: the supplier Guangzhou City tea, hui fine chemical Co., ltd; the camellia seed oil is of a brand;
butter tree fruit fat: the suppliers' insurance shortcuts (Shanghai) international trade company; brand LIPEX SHEA;
tapioca starch: the supplier Guangzhou market Bai Hao Co., ltd; brand DRY-FLO TS PURE;
modified corn starch: the vendor Guangzhou Korotten New Material technologies Co., ltd; brand KLD CS11;
flos Chrysanthemi Indici (CHRYSANTHEMUM INDICUM) flower extract: the supplier Guangzhou Chaozhou Biotech Co., ltd; the brand Senplan ™ BBA-ET FREE;
honeysuckle (LONICERA JAPONICA) flower extract: the supplier Guangzhou Chaozhou Biotech Co., ltd; the brand Senplan ™ BBA-ET FREE;
rheum PALMATUM (Rheum PALMATUM) root extract: the supplier Guangzhou Chaozhou Biotech Co., ltd; the brand Senplan ™ BBA-ET FREE;
golden chamomile (CHRYSANTHELLUM INDICUM) extract: the supplier Guangzhou Chaozhou Biotech Co., ltd; the brand Senplan ™ BBA-ET FREE;
kuh-seng (SOPHORA FLAVESCENS) extract: the supplier Guangzhou Chaozhou Biotech Co., ltd; the brand Senplan ™ BBA-ET FREE;
aloe BARBADENSIS (Aloe BARBADENSIS) leaf extract: the supplier Guangzhou Hengtao trade Limited; aloe vera gel juice a02-3.
Examples
A preparation method of the body lotion comprises the following steps:
step 1: preparing a water phase, mixing and stirring the raw materials to obtain the water phase; stirring at 85-90deg.C for 40min;
step 2: preparing an oil phase, mixing and stirring all the raw materials to obtain the oil phase; stirring at 85-90deg.C for 40min;
step 3: preparing emulsion, mixing oil phase and water phase, homogenizing and dispersing for 3-5 min, stirring and cooling to 40-45deg.C, adding plant extract to obtain emulsion;
step 4: adding the powder into the emulsion, and stirring uniformly.
Examples 1 to 8
Referring to the preparation method of the examples, the formulations of examples 1-8 are referred to Table 1;
table 1 formulation table
Figure SMS_1
Comparative examples 1 to 3
The formulations of comparative examples 1-3 are referred to in Table 2 with reference to the preparation method of the examples;
table 2 formulation table
Figure SMS_2
Comparative examples 4 to 6
The formulations of comparative examples 4-6 are referred to in Table 3 with reference to the preparation method of the examples;
table 3 recipe table
Figure SMS_3
/>
Examples 9 to 10
Referring to the preparation method of the examples, the formulations of comparative examples 7 to 8 are referred to Table 4;
table 4 formulation table
Figure SMS_4
Body-refreshing effect test
The testing method comprises the following steps: and (3) smearing corresponding products on the inner side of the arm, and judging dryness of the smeared skin by dipping the sample and the blank group with the small paper scraps. The smaller the amount of small paper scraps is, the better the body refreshing effect is.
The test results are shown in tables 5 and 6;
TABLE 5 body-refreshing effect
Examples and comparative examples Quantity of small paper scraps (sheet) Picture picture
Blank space 50 FIG. 1
Example 1 3 FIG. 2
Example 2 9 FIG. 3
Example 3 6 FIG. 4
Example 4 8 FIG. 5
Example 5 6 FIG. 6
Example 6 3 FIG. 7
Example 7 6 FIG. 8
Example 8 2 FIG. 9
Comparative example 1 25 FIG. 10
Comparative example 2 15 FIG. 11
Comparative example 3 15 FIG. 12
Comparative example 4 10 FIG. 13
Comparative example 5 18 FIG. 14
Comparative example 6 11 FIG. 15
The stability test results of examples and comparative examples are referred to table 6;
table 6 results of performance testing of examples and comparative examples
Figure SMS_5
Analysis of results:
1. according to the dryness of Table 5 and the smearing results of Table 6, the compatibility of the tapioca starch, the modified corn starch and the silica is the best; the tapioca starch and the modified corn starch have certain thickening effect in the formula besides the body refreshing effect, so that the stability of the formula is improved; the silica can increase the smoothness of skin, reduce the thick feel of coating the tapioca starch and the modified corn starch, and the three can be compounded to have a synergistic effect.
The tapioca starch, the modified corn starch and the silica are compounded to control a certain addition amount, so that light, thin, dry and velvet-like smearing feeling can be provided, grease can be absorbed, and meanwhile, the whitening effect can not be generated on the skin; the body refreshing dew releases the cassava starch, the modified corn starch and the silica to achieve the body refreshing effect and ensure the skin moisture retention in the smearing process, any component is possibly deleted or replaced to change the body refreshing effect, the moisture retention and the dryness performance are deteriorated, and the whitening phenomenon can also occur after the skin is dried.
Tapioca starch and modified corn starch are polysaccharide substances, a plurality of hydroxyl groups exist, the hydroxyl groups are contacted with moisture and sweat on the surface of skin, the formed hydrogen bond is intermolecular force, and the tapioca starch and the modified corn starch can feel sticky when feel touch again, so that the tapioca starch and the modified corn starch can produce sticky thick feel when being used too much, and the effects of sweat absorption and body refreshing cannot be achieved when the dosage is too little. The silica with good absorption effect can increase the smoothness of skin, reduce the thick sense of coating tapioca starch and modified corn starch, and can adsorb fatty acid lipid components secreted by sebaceous glands to achieve the effect of refreshing the body.
2. From examples 1, 9, 10 in table 6, it was found that polyglycerol-3 methyl glucose distearate as an emulsifier had a lower effect on the skin feel of the formulation and ensured stability, being a better emulsification protocol.
Any other changes, modifications, substitutions, combinations, and simplifications that do not depart from the spirit and principles of the invention are intended to be equivalent arrangements included within the scope of the invention.

Claims (2)

1. The body lotion is characterized by comprising the following components in percentage by weight:
5% of glycerol;
hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer 1%;
3.7% of butanediol;
panthenol 0.5%;
1,2 hexanediol 0.8%;
isononyl isononanoate 2%;
jojoba seed oil 1%;
0.5% of camellia seed oil;
tocopherol acetate 0.2%;
0.5% of butter tree fruit fat;
1.0% of polyglycerol-3 methyl glucose distearate;
powder: 12%;
0.5% of wild chrysanthemum extract;
0.5% of honeysuckle extract;
0.5% of rheum palmatum root extract;
0.5% of golden chamomile extract;
0.5% of kuh-seng extract;
aloe vera leaf extract 0.5%;
deionized water was added to 100%;
the powder comprises tapioca starch, modified corn starch and silica; the weight ratio of the tapioca starch to the modified corn starch to the silica is 4:3:5 or 4:4:4.
2. A method for preparing the body lotion according to claim 1, comprising the steps of:
step 1: preparing a water phase, mixing and stirring glycerol, hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer, butanediol, panthenol, 1,2 hexanediol and deionized water to obtain a water phase; stirring at 85-90deg.C for 40min;
step 2: preparing an oil phase, mixing isononyl isononanoate, jojoba seed oil, camellia seed oil, tocopherol acetate, shea butter, polyglycerol-3 methyl glucose distearate and stirring to obtain an oil phase; stirring at 85-90deg.C for 40min;
step 3: preparing emulsion, mixing oil phase and water phase, homogenizing and dispersing for 3-5 min, stirring and cooling to 40-45deg.C, adding flos Chrysanthemi Indici extract, flos Lonicerae extract, radix et rhizoma Rhei Palmati root extract, flos Matricariae Chamomillae extract, radix Sophorae Flavescentis extract, and Aloe vera leaf extract to obtain emulsion;
step 4: adding the powder into the emulsion, and stirring uniformly.
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