CN115869100B - Laboratory dissecting table for murine animals - Google Patents

Laboratory dissecting table for murine animals Download PDF

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Publication number
CN115869100B
CN115869100B CN202310112817.7A CN202310112817A CN115869100B CN 115869100 B CN115869100 B CN 115869100B CN 202310112817 A CN202310112817 A CN 202310112817A CN 115869100 B CN115869100 B CN 115869100B
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China
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mouse
rotating plate
clip
clamping
chassis
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CN115869100A (en
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王全军
董延生
郭明刚
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Guoke Saifu Hebei Pharmaceutical Technology Co ltd
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Guoke Saifu Hebei Pharmaceutical Technology Co ltd
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    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

The invention relates to the technical field of murine dissection equipment, in particular to a murine animal experiment dissection table, which comprises: the chassis is horizontally arranged on the table; the chassis is provided with a clamping device which is convenient for clamping the neck of the mouse so as to kill the mouse by using a neck dislocation method, and is provided with a fixing device which is used for rapidly fixing the limbs of the mouse after the mouse is killed. Compared with the existing laboratory dissecting table for the murine animals, the laboratory dissecting table for the murine animals is provided with the clamping device for clamping the neck of the mice, the neck of the mice does not need to be grasped by hands in the process of dislocation and sacrifice of the neck of the mice, the situation that the mice resist and bite the fingers due to fear of the mice or unfamiliar with the dislocation and sacrifice method of the neck of students in the teaching experiment process is avoided, the life health of the students in the experiment process is ensured, the time for preparing is reduced, the students obtain more dissection and observation time in a classroom, and the efficiency of the classroom is improved.

Description

Laboratory dissecting table for murine animals
Technical Field
The invention relates to the technical field of murine dissection equipment, in particular to a murine animal experiment dissection table.
Background
The abdominal dissection experiment of the murine animal can enable students to understand the body structure of the murine more deeply, and is an important teaching experiment in the teaching process.
In the teaching process, most beginners are easy to fear mice because the beginners are not contacted with the mice at ordinary times, in the process of killing the mice by a neck dislocation method, the process of killing the mice can occupy more teaching time because of unfamiliar of the technical method and unskilled operation, and the struggling of the mice can lead the beginners to be worried by the heart, so that the accident that the students are bitten by the mice is easy to occur, although the beginners are artificially cultured mice for teaching, the students are also easy to be infected by bacteria and viruses after being bitten, the time of teaching can be occupied by treating wounds after injury, and the organization of the necks of the mice is easy to be damaged to a greater extent because the students are hard in fear, so that the clear observation of the students is not facilitated after the organization of the neck is anatomic.
In addition, after the mice are killed by cervical dislocation, the abdomen of the mice is fixed on the operation panel upwards before the dissection is started, and the traditional fixing mode is to pin the limbs of the mice on the operation panel by using a pin or bind the limbs of the mice on the operation panel by using a rope. Because the four limbs of the mouse are thinner, the mouse needs to be aligned slowly when being fixed by the pin, and the rope needs to be knotted four times when being fixed, one set of operation wastes the anatomical teaching time, so that students cannot fully know and learn the body and physiological structure of the mouse in limited classroom time, and the classroom efficiency is low.
Therefore, the rat animal experiment dissecting table is provided, the contact between students and rats is reduced, the fear of the students to the rats is reduced, the students can quickly kill the rats, the limbs of the rats are quickly fixed, the preparation work before the rat dissecting experiment is saved, and therefore the students can have more time to perform dissecting operation and observe and learn the structures and tissues of the body of the rats.
Disclosure of Invention
The invention aims to provide a laboratory dissecting table for a murine animal, which is convenient for students to quickly fix the neck of the mouse by arranging a clamping device, is convenient for killing the mouse by a neck dislocation method, and prevents the students from being bitten by struggling of the mouse; the fixing device is further arranged, the fixing device clamps the four limbs of the mouse rapidly after the mouse is killed, the time required for fixing the four limbs of the mouse before an anatomic experiment is reduced, and students can have more sufficient time for anatomic and observing the mouse.
In order to achieve the above purpose, the present invention provides the following technical solutions:
a murine experimental dissecting table comprising:
the chassis is horizontally arranged on the table;
the clamping device is characterized in that the chassis is provided with a clamping device which is convenient for clamping the neck of the mouse so as to kill the mouse by using a neck dislocation method, the clamping device can be in a clamping mode by using an air cylinder, can also be in a clamping mode by using a screw rod, can also be used for clamping other devices or mechanisms capable of clamping the neck of the mouse, is provided with a fixing device which is used for rapidly fixing the limbs of the mouse after the mouse is killed, and can be automatically clamped and fixed by using a manipulator, and can also be used for rapidly fixing other limbs of the mouse. Through clamping device to the clamp of mouse neck, can avoid the student to snatch the mouse when snatching the mouse neck and the mouse is stung, reduced the risk of being infected because of the mouse stung, ensured student's life health, after pressing from both sides tight to the mouse neck through clamping device, the student pulls the tail of mouse fast and can carry out the dislocation punishment of neck to the mouse, start fixing device afterwards, fixing device fixes the four limbs of mouse fast, can reduce the student and take in the in-process of fixing the mouse four limbs, let the student can have more time to dissect and observe the mouse health in the limited time of classroom, promoted the efficiency of classroom.
Preferably, the clamping device comprises a fixed block fixedly mounted on the chassis, the fixed block is fixedly mounted on the upper surface close to one end of the chassis, a supporting plate for supporting the neck of a mouse is fixedly mounted on the side wall of the fixed block, a first sliding block is slidably mounted on the upper surface of the chassis, a first spring is horizontally arranged between the first sliding block and the fixed block, one end of the first spring is fixed on the side wall of the fixed block, the other end of the first spring is fixed on the side wall of the sliding block, a rotating plate is rotatably mounted on the first sliding block, a limiting block for limiting the rotation angle of the rotating plate is arranged on the sliding block, the limiting block is matched with the sliding block, the rotating plate can only rotate within a range of 0 DEG to 90 DEG, a pressing part matched with the supporting plate for clamping the neck of the mouse is fixedly mounted on the rotating plate, the pressing part can be a rubber block or a silica gel block, or other mechanism or device capable of being matched for pressing and fixing the neck of the mouse is rotatably mounted on the side wall of the chassis, a pin roll is arranged on the handle, a pin roll is fixedly mounted on the side wall of the rotating plate, a rotating plate is provided with a notch, a rotating shaft is rotatably arranged on the rotating plate, a rotating device is arranged below the rotating device, the chassis can be used for driving the chassis, and the chassis can rotate conveniently and can rotate, and can also rotate and can rotate by a device.
When the mouse is used, the right hand grabs the tail of the mouse to lift the mouse wholly, then lifts the lifted mouse between the first slider and the fixed block, the neck of the mouse is aligned to the supporting plate, then the left hand pulls the handle to rotate towards the direction of the fixed block, the rotating plate rotates along with the handle due to the pin shaft, when the rotating plate rotates to form an included angle of 90 degrees with the chassis, the pressing part and the supporting plate are compressed by the spring along with the continued rotation of the handle, the slider moves towards the direction of the fixed block, the pressing part gradually approaches to the supporting plate, and finally the pressing part and the supporting plate clamp the neck of the mouse together. The right hand that grabs the mouse tail fast pulls the tail of mouse and can dislocation the sacrifice of its neck, need not to go to with the hand and hold the neck of mouse, has avoided the condition emergence of being stung by the mouse, simultaneously, lets the mouse death fast in order to reduce the misery of mouse, also accords with humanoid.
The interval distance between the first sliding block and the fixed block is used for freeing a space so as to clamp mice with different sizes; the first spring is used for automatically resetting the sliding block; the adoption is turned the board and is mutually supported with the handle, is turned the board and is pressed from both sides tightly to the mouse neck with the cooperation layer board again after vertical, because with the mouse vertical claw that hangs the back mouse do not have the support to support, control the mouse more easily, and if keep flat the mouse and put on the desk again, even seize tail mouse also can lean on the claw to creep everywhere, be unfavorable for the student to control the mouse.
Preferably, the pressing part comprises a reed which is fixedly arranged on the rotating plate and is opposite to the supporting plate and used for clamping the back neck of the mouse, the reed is in a herringbone shape, the reed is made of metal, the thickness of the reed is 1-1.5mm, the herringbone reed can deform and continuously clamp and limit the neck of the mouse when pressing the neck of the mouse, a space is reserved for the cervical vertebra of the mouse in the clamping process, the cervical vertebra of the mouse cannot be clamped off to damage the neck tissue of the mouse, the herringbone reed is more in line with the gesture of a person pressing the neck of the mouse with two hands to perform a cervical dislocation method, the two ends of the bifurcation of the reed are bent towards the direction of the rotating plate, and the two ends of the bent reed are favorable for enabling the reed to continuously deform and continuously reduce the space enclosed by the reed when making extrusion contact with the supporting plate, so as to realize continuous clamping of the neck of the mouse. Meanwhile, the two ends of the bent reed can not puncture the neck tissues of the rat when being carelessly clamped to the flesh of the neck of the rat.
Further, the outer surface of the reed is uniformly wrapped with a soft layer, the soft layer can be soft silica gel or soft rubber, and the thickness of the soft layer is 1-3 mm. Because the reed is lamellar, when pulling the tail of mouse, the pressure of the place that mouse head and reed contacted is great, appears the impaired condition of head tissue easily and takes place, in order to keep the body tissue of the experiment body intact so that follow-up dissection as far as possible, sets up soft layer and reduces the damage that causes the head tissue of mouse.
Preferably, the fixing device comprises two rectangular clips rotatably mounted on the rotating plate and used for clamping four limbs of a mouse, the clips are of rectangular frame-shaped structures, the two clips are symmetrically mounted on the supporting plate, each clip is provided with a torsion spring, each torsion spring keeps the tendency of the clip to be attached to the rotating plate, each clip has a tendency of rotating towards the center of the clamping plate under the action of the torsion springs, the two clips are not contacted with each other after being clamped, but are spaced by a certain width, and the spacing width is about 10% -30% larger than the width of the mouse. And a limiting module used for temporarily limiting the clip is arranged beside each clip, and the limiting module can be a limiting rod, a limiting block or other devices or mechanisms capable of limiting the rotation trend of the clip.
Under normal conditions, the two clips are in a state of being attached to the rotating plate under the action of the torsion springs respectively installed, the two clips are rotated towards the direction away from each other before being used, the clips are loosened when the two clips are rotated to the position greater than 90 degrees between the two clips and the rotating plate, the limiting modules limit the positions of the clips, the clips are attached to the rotating plate again under the action of the torsion springs after avoiding loosening hands, then the north part of a mouse faces the clamping plate, the abdomen faces the direction of the supporting plate, the mouse tail is pulled to kill after the neck is clamped by the pressing part and the supporting plate, the two limiting modules are removed, after the limiting modules are removed, the two clips lose the constraint of the limiting modules, the two clips rotate towards the direction of the rotating plate again and are attached to the rotating plate under the action of the torsion springs, the width between the closed clips is greater than the body width of the mouse, so that the mouse can not be clamped to the abdomen of the mouse, and the clips on each side can hook the front limb and the back limb of the mouse towards the rotating plate in the direction of the rotating plate in the process of the mouse in order to fix the four limbs conveniently. The mode can fix all the four limbs of the mice by the following son without fixing the four limbs of the mice one by one, and saves the time required by fixing the four limbs of the mice. After the four limbs of the mice are fixed, the abdomen dissection can be carried out on the mice by only rotating the handle to put the rotating plate flat.
Preferably, the rotating device comprises a base arranged below the chassis, a rotating shaft is arranged in the middle of the base, a gear is horizontally and fixedly arranged at the bottom of the chassis, the gear is rotatably arranged on the rotating shaft in the middle of the base, and a bolt for positioning the gear is horizontally and slidably arranged on the side wall of the base. After the mice are killed and clamped and fixed, the neck of the mice needs to be aligned with the supporting plate when the mice are killed because the back of the mice faces the rotating plate, so the mice need to stand on one face of the abdomen of the mice, when the rotating plate is put flat, the head of the mice faces the user of the equipment, the direction of the mice can be adjusted by rotating the chassis by 180 degrees, the mice are convenient to dissect the abdomen, after the angle adjustment is finished, the bolts are inserted between the teeth of the gears, the chassis is positioned, the phenomenon that the chassis is carelessly rotated when the mice are dissected is avoided, errors in the dissecting process are caused, the chassis is rotated for different angles after the bolts are pulled out when the viscera tissues of the mice are observed, and the convenience of the equipment is improved.
Further, every the inclined fixed mounting of clip front end has splint, and splint forward stretch out, and the contained angle that splint and the plane of clip formed is between 120 to 140, and 120 to 140 contained angles can be more easily with the claw of mouse when the claw of clip rotation clamp mouse, and if when carelessly collude the belly of mouse, can not hook the belly of mouse like the hook that turns back again, guarantee that the belly tissue of mouse is complete, every offer on the splint and be used for conveniently blocking the wavy tooth of mouse claw, the interval of tooth is 3-5mm, and the existence of tooth can block the claw of mouse between two teeth, lets the fixing of mouse four limbs more firm, avoids rocking at anatomical in-process, influences the dissection, has improved the stability in use of equipment.
Further, each clip is fixedly provided with a plurality of poking sheets, the width of each poking sheet is the same as the width of teeth on the clamping plate, each poking sheet is made of plastic sheets, the thickness of each sheet is between 0.3 and 0.6mm, a plurality of poking sheets are connected left and right to form a full clip, each poking sheet is parallel to the clamping plate, each poking sheet is closer to the rotating shaft of the clip than the clamping plate, the distance between each poking sheet and the clamping plate is 5-10mm, and the length of each poking sheet is about twice the width of the clamping plate. When the clamp rotates to clamp the paws of the mice, the limbs are easy to retract after the mice die because the postures of the limbs are different, at the moment, the clamp is easy to empty with the clamping plate, and after the poking plate is arranged, the poking plate stretches longer than the clamping plate, so that the claw retracted by the mice is easier to contact, after the claw of the mice is contacted, the claw of the mice is poked towards the side edge of the body of the mice, then the clamping plate is easier to contact and clamp the paws of the mice, and the overlong poking plate is deformed and bent after the poking plate contacts the body of the mice, so that the abdomen of the mice is not shielded, and the abdomen dissection of the mice is not influenced. Further improving the stability of the equipment.
Preferably, an adjusting device which is convenient for a user to adjust the killing force when the mouse is killed by the cervical dislocation method is further arranged on the rotating plate above the clip. The adjusting device comprises a second spring which is arranged at one end of the rotating plate, away from the rotating point, parallel to the surface of the rotating plate and is convenient to adjust cervical vertebra force of the broken mice, the second spring is an extension spring, one end of the second spring, close to the pressing part, is provided with a hook, a sliding groove is formed in the rotating plate, the sliding groove is located at the right center of the two clips and is symmetrical to the sliding groove, a sliding block is slidably arranged on the sliding groove, and a clip used for fixing tails of the mice is arranged on the sliding block. After the neck of the mouse is clamped, the tail of the mouse is clamped and hung on the second sliding block through the clamp, the mouse is preliminarily fixed at the moment, the second spring is pulled downwards from the top, the hook on the second spring is hung below the second sliding block, the second spring is loosened, the cervical vertebra of the mouse is pulled to be dislocated under the action of the spring elastic force suddenly received, the situation that a beginner holds bad force is avoided, the neck tissue of the mouse is excessively damaged due to overlarge using force, and the follow-up observation of the neck tissue is influenced. The third spring is used for pulling, and the pulling force can be adjusted by adjusting the distance between the second slider and the second spring in the initial state. Simultaneously, preliminarily fix the mouse on the rotating plate, reed and clip ensure that the mouse is located the centre of two presss from both sides the knot, also are favorable to follow-up presss from both sides to clamp the fixing to the mouse four limbs. Further improving the stability of the clip.
Preferably, the limit module comprises a lock body fixedly mounted on the rotating plate, the lock body is positioned at the top of the clip when the rotating plate is vertical, a lock tongue used for clamping the clip is slidably mounted in the lock body, a spring III is arranged between the lock tongue and the lock body, the spring III always keeps the lock tongue extending out of the lock body towards the reed, a steel wire is fixedly mounted at one end of the lock tongue, and the steel wire penetrates through the lock tongue and is connected to the second slider. The spring bolt that stretches out can block the clip, lets the clip keep open state, when using spring two to carry out neck dislocation method punishment to the mouse, slider two is upwards pulled, slider two will pull the steel wire this moment, the steel wire drives the spring bolt and withdraws the lock body inside, spring three compression has lost the spacing of spring bolt, the clip can rotate and press from both sides the four limbs of tight mouse towards the direction of rotating the board under the effect of torsional spring, the realization is pressed from both sides the four limbs of tight to the mouse when finishing the mouse punishment, reduce the time of manual contact limit module, the work convenience of lifting means. Meanwhile, as the four limbs of the mice can keep stretching out and struggling at the moment of killing the mice, the clamp is easier to clamp the four limbs of the mice for fixing, and the use stability of the fixing device is further ensured.
Compared with the prior art, the invention has the beneficial effects that:
1. compared with the existing laboratory dissecting table for the murine animals, the laboratory dissecting table for the murine animals is provided with the clamping device for clamping the neck of the mice, so that the neck of the mice does not need to be grasped by hands in the process of dislocation and killing the mice, the situation that the mice resist and bite fingers due to fear of the mice or unfamiliar with the dislocation and killing method of the neck in the teaching experiment process is avoided, the life health of the students in the experiment process is ensured, the painless death of the mice is accelerated, the pain of the mice in death is reduced, and the laboratory dissecting table also accords with humanoid spirit. The mice are killed only as a preparation work of the anatomic experiment, so that the time of the preparation work is reduced, students can obtain more anatomic and observing time in a classroom, and the efficiency of the classroom is improved.
2. Compared with the existing rodent dissecting test bed, the rodent dissecting test bed is provided with the fixing device, and the fixing device can clamp the limbs of the mice onto the rotating plate at one time by removing the limiting modules beside the two clips after killing the mice through the two clips arranged on the two sides of the rotating plate without fixing the mice one by one. Realizes the rapid fixation of the rat claw and saves the time required for the claw fixation. Then put the commentaries on classics board and put the flat experiment of dissecting to the mouse, can also adjust the direction of mouse through the rotating device who rotates the chassis below in the experimentation, the student of being convenient for dissects and observes the mouse.
3. The invention discloses a laboratory dissecting table for a murine animal, which is provided with a spring II and a slide block II, wherein a clamp is arranged on the slide block II, the clamp clamps the tail of a mouse to be primarily fixed, a hook on the spring II is pulled to be hung on the slide block II, then the spring II is released, the cervical vertebra of the mouse is quickly contracted and broken through the spring II, the stretching length of the spring can be adjusted through adjusting the distance between the clamp and the hook, finally the strength when the tail of the mouse is pulled is adjusted, the spring II, the clamp and the slide block are combined to kill the mouse by a cervical dislocation method, the strength when the mouse is killed can be set more objectively, and the cervical vertebra of the mouse is ensured to be broken and the neck tissue of the mouse is not damaged due to excessive force. The second slider is connected with two limit modules for locking two clips through steel wires, when the second slider is pulled upwards by the spring to kill the mice, the two limit modules are pulled by the steel wires, the limit to the clips is released by the two limit modules, the clips can be started and the limbs of the mice are simultaneously pressed on the rotating plate to be fixed, people do not need to manually release the two limit devices, the operation of the device is simpler and more convenient, the time required for killing and fixing the mice is further saved, and the teaching efficiency is further improved.
Drawings
FIG. 1 is a schematic perspective view of the present invention;
FIG. 2 is an enlarged view of the invention at A in FIG. 1;
FIG. 3 is an enlarged view of the invention at B in FIG. 1;
FIG. 4 is a front view of the present invention;
FIG. 5 is a right side view of the present invention;
FIG. 6 is a cross-sectional view taken at C-C of FIG. 5 in accordance with the present invention;
FIG. 7 is a schematic diagram of the structure of the front and back actions of the clip for clamping a mouse limb according to the present invention;
FIG. 8 is a schematic view of the mounting structure between the clip, cleat and plectrum of the present invention;
FIG. 9 is a schematic bottom perspective view of the turning device of the present invention;
FIG. 10 is a schematic view showing the mounting structure between the clip and the rotating plate according to the second embodiment of the present invention;
fig. 11 is a schematic perspective view of a clip and a cylinder according to a second embodiment of the present invention.
In the figure: 1. a chassis; 2. a fixed block; 3. a supporting plate; 4. a first sliding block; 5. a first spring; 6. a rotating plate; 7. a limiting block; 8. a handle; 9. a notch; 10. a pin shaft; 11. a clip; 12. a torsion spring; 13. a base; 14. a gear; 15. a plug pin; 16. a reed; 17. a soft layer; 18. a clamping plate; 19. a pulling piece; 20. a second spring; 21. a hook; 22. a chute; 23. a clip; 24. a lock body; 25. a bolt; 26. a third spring; 27. a steel wire; 28. a cylinder; 29 second slide block.
Detailed Description
Embodiment one: the body width of the mice was 30mm.
Referring to fig. 1 to 9, a murine experimental dissecting table comprising: 1. a chassis; 2. a fixed block; 3. a supporting plate; 4. a first sliding block; 5. a first spring; 6. a rotating plate; 7. a limiting block; 8. a handle; 9. a notch; 10. a pin shaft; 11. a clip; 12. a torsion spring; 13. a base; 14. a gear; 15. a plug pin; 16. a reed; 17. a soft layer; 18. a clamping plate; 19. a pulling piece; 20. a second spring; 21. a hook; 22. a chute; 23. a clip; 24. a lock body; 25. a bolt; 26. a third spring; 27. a steel wire; 29 second slide block.
The base 13 is horizontally and fixedly arranged on a tabletop, a rotating shaft is arranged in the middle of the base 13, a gear 14 is horizontally and fixedly arranged at the bottom of the base 1, the gear 14 is rotatably arranged on the rotating shaft in the middle of the base 13, the gear 14 can rotate relative to the base 13, a bolt 15 is horizontally and slidably arranged on the side wall of the base 13, the front end of the bolt 15 is in a shape meshed with a tooth groove of the gear 14, a fixed block 2 is fixedly arranged on the right side of the base 1, a supporting plate 3 is fixedly arranged on the left upper side of the fixed block 2, a first slider 4 is slidably arranged on the base 1 and is positioned on the left side of the fixed block 2, a first spring 5 is horizontally arranged between the first slider 4 and the fixed block 2, one end of the first spring 5 is fixed on the fixed block 2, the other end of the first slider 4 is rotatably provided with a rotating plate 6, a limiting block 7 is fixedly arranged on the first slider block, the rotating plate 6 is only capable of rotating in a range of 0 DEG under the limiting of the limiting block 7 and the tooth groove of the first slider 4, a cylindrical handle 8 is fixedly arranged on the side wall of the rotating plate 6, a pin 10 is fixedly arranged on the side wall of the rotating plate 6 and is provided with a cylindrical handle 8, and a handle 8 is connected with a handle 8 through a pin 9, and a handle 8 is rotatably arranged on the handle 8 and a handle 8 is connected with a pin 9 through a pin 9. The reed 16 is fixedly arranged on the vertical center plane of the rotating plate 6, the reed 16 is in a herringbone shape, the fork of the reed 16 in the herringbone shape is opposite to the supporting plate 3 when the rotating plate 6 is vertical, the thickness of the reed 16 is 1mm, the reed 16 is made of spring steel, both ends of the fork of the reed 16 in the herringbone shape are bent towards the direction of the rotating plate 6, all the outer surfaces of the reed 16 are uniformly wrapped with a soft layer 17, the soft layer 17 is made of soft transparent silica gel, and the thickness of the soft layer 17 is 2mm. Taking the case that the rotating plate 6 is vertical as an example, a chute 22 is further formed in the vertical center plane of the rotating plate 6, the chute 22 is positioned right above the reed 16, a second slider 29 is slidably arranged in the chute 22, one end of the second slider 29 exposed out of the chute 22 is fixedly provided with a clip 23, a second spring 20 is further vertically hung right above the chute 22, the second spring 20 is an extension spring, the bottom of the second spring 20 is curled into a hook 21, two rectangular frame-shaped clips 11 surrounded by round rods are symmetrically and rotatably arranged on the vertical center plane of the rotating plate 6, each clip 11 is provided with a torsion spring 12 at the position of a rotating shaft, the torsion spring 12 always presses the clip 11 on the surface of the rotating plate 6, the upper part of each clip 11 is fixedly provided with a clamping plate 18 in an inclined manner in the direction of 120-degree included angle with the plane of the clip 11 towards the direction of the rotating plate 6, the clamping plate 18 is made of an ABS plastic plate with the thickness of 2mm, the length of the clamping plate 18 is the same as that of the clip 11, the width of the clamping plate 18 is 15mm, wavy teeth are formed at the front end of each clamping plate 18, the width of each tooth and a tooth slot is 4mm, a row of poking plates 19 are fixedly arranged on each clip 11 along the width direction of the clip 11 and at the position of 1810mm away from the clamping plate, each poking plate 19 is made of a PP transparent plastic sheet, the thickness of each poking plate 19 is 0.4mm, the width of each poking plate 19 is the same as that of the front end of the clamping plate 18, the length of each poking plate 19 is twice the width of the clamping plate 18, and each poking plate 19 is parallel to the clamping plate 18. When the clamping plate 18 at the front end of the clamping buckle 11 is clamped with the surface of the rotating plate 6, the minimum distance between the two clamping plates 18 is 120% of the width of the mouse body. A lock body 24 is vertically and downwards fixedly arranged on the rotating plate 6 on the upper side of each clip 11, a lock tongue 25 is vertically and downwards slidably arranged on each lock body 24, a spring III 26 is arranged between the top of each lock tongue 25 and the inner top of the lock body 24, a steel wire 27 is fixedly connected to the top of each lock tongue 25, and each steel wire 27 penetrates through the lock body 24 and is fixedly connected with a slider II 29.
The specific working procedure is as follows:
before working: the handle 8 is put flat, the handle 8 drives the rotating plate 6 to be put to the horizontal at the same time, whether the bolt 15 is in a pulled-out state is checked, and if so, the bolt 15 is inserted towards the base 13. Then the two clips 11 are respectively rotated towards the directions away from each other by the two hands until the two clips 11 respectively pass over the two lock tongues 25, the lock tongues 25 firstly move towards the inside of the lock body 24, then when the clips 11 pass over, the two clips 11 are respectively released by the two hands after the two clips 11 extend out of the lock body 24 under the action of the spring III 26, the clips 11 rotate and close towards the rotating plate 6 under the action of the torsion springs 12, and the clips 11 cannot rotate and close towards the rotating plate 6 due to the limiting reason of the lock tongues 25 on the clips 11.
When in operation, the device comprises: the front face faces the fixed block 2, the first slider 4 is located behind the fixed block 2, the tail of the mouse is grabbed by the right hand to lift the mouse, the abdomen of the mouse faces the right hand, the back of the mouse faces the rotating plate 6, the neck of the mouse is aligned with the center of the supporting plate 3, then the left hand pulls the handle 8 towards the fixed block 2, the handle 8 drives the pin shaft 10, the rotating plate 6 rotates towards the fixed block 2 until the rotating plate 6 is vertical, the reeds 16 on the vertical rotating plate 6 are aligned with the supporting plate 3 from the rear neck of the mouse, then the handle 8 is pulled towards the fixed block 2, the rotating plate 6 and the rotating plate cannot rotate continuously, the handle 8 drives the first slider 4 to move towards the rotating plate 6, the spring 5 compresses, the reed 16 in a figure-shaped form is clamped from the rear of the mouse after the first slider 4 is continuously moved towards the fixed block 2, the reed 16 in the figure-shaped form is extruded until the reed 16 is vertically aligned with the supporting plate 3, and finally the space between the reed 16 and the supporting plate 3 is smaller and the neck of the mouse is simulated. Then, the tail of the mouse is hung at the clamp 23 on the second slider 29 by the right hand, the mouse is initially fixed, the second spring 20 is pulled downwards by the right hand from the top, the hook 21 at the bottom end of the second spring 20 is pulled to the lower side of the second slider 29, then the right hand is loosened, the second spring 20 is quickly retracted under the action of self-elastic force, the hook 21 at the lower end of the second spring 20 pulls the second slider 29 to quickly move upwards in the retracting process of the second spring 20 and gives the second slider 29 an impact force, the tail of the mouse is pulled by the sudden and quick movement of the second slider 29, the cervical vertebra of the mouse is pulled to dislocation, and the purpose of killing the mouse by a neck dislocation method is achieved.
When the second slider 29 is pulled by the second spring 20 to move upwards, the two lock tongues 25 connected with the second slider 29 by the steel wires 27 are pulled upwards by the second spring 20, the third spring 26 is compressed, the two clamping buckles 11 limited by the lock tongues 25 are lost, the two clamping buckles rotate to be closed towards the direction of the clamping plate 18 under the action of the respective torsion springs 12, in the closing process, the poking plate 19 at the front end of the clamping buckle 11 can firstly contact with the claw of a mouse and poke the claw of the mouse towards the two sides of the mouse, then the clamping plate 18 in front of the poking plate 19 hooks the claw of the mouse and presses the claw of the mouse towards the direction of the rotating plate 6, the poking plate 19 is extruded to deform after contacting the body of an old mouse, the abdomen of the mouse is not shielded, and wavy teeth at the front end of the clamping plate 18 can clamp the claw of the mouse, so that the mouse is more stably fixed.
Then the left hand pushes the handle 8 towards the position far away from the fixed block 2, the handle 8 is pushed to be in a horizontal state, the rotating plate 6 is also restored to be in a horizontal state under the drive of the handle 8, then the plug 15 is pulled out, the chassis 1 is rotated 180 degrees, the tail of a mouse faces the mouse, finally the plug 15 on the side wall of the base 13 is reinserted into a tooth groove of a gear 14 in the base 13, the base 13 is fixed, and then the mouse can be subjected to an anatomical experiment operation.
After working: the hook 21 is taken down from the second slider 29, and the third spring 26 drives the second slider 29 to reset with the lock tongue 25. The two clips 11 are unfolded, the mice are removed from the swivel plate 6, and the cleaning equipment is then performed with sterile alcohol.
Embodiment two:
referring to fig. 10 and 11, the first difference from the embodiment is that: the two clips 11 are in a T shape, the two clips 11 penetrate through the rotating plate 6 and are slidably mounted on the rotating plate 6, the two clips 11 are symmetrically mounted in an inclined mode towards the central plane of the rotating plate 6 where the sliding block II 29 is located, and an included angle of 45 degrees is formed between the two clips 11 and the rotating plate 6. Two small-sized air cylinders 28 are fixedly arranged on the back of the rotating plate 6, each air cylinder 28 is communicated with an external air source, and the output ends of the two air cylinders 28 are fixedly connected with the two clips 11 respectively. Each clip 11 is provided with a clamping plate 18 and a row of poking sheets 19 at the front end, and the included angle between the clamping plate 18 and the clip 11 is 90 degrees. When the clips 11 are clamped against the swivel plate 6, the minimum distance between the two clamping plates 18 on the two clips 11 is 50% greater than the body width of the mouse.
Before the mice are killed, the two air cylinders 28 drive the two clips 11 to extend, after the mice are killed, the two air cylinders 28 are controlled to exhaust and retract, the two air cylinders 28 drive the two clips 11 to retract towards the rotating plate 6, the poking plate 19 firstly pokes the paws of the mice in the retracting process, then the clamping plate 18 hooks the paws of the mice and then continues to drive the paws of the mice to move towards the rotating plate 6, and finally the paws of the mice are pressed on the rotating plate 6 to be fixed.
Compared with the first embodiment, the second embodiment can not automatically clamp the paw of the mouse while killing the mouse, and the retraction of the manual control cylinder 28 is needed, but the inclined clip 11 in the second embodiment is more convenient for hooking the limb of the mouse, the stability of hooking the limb of the mouse is higher than that in the first embodiment, and meanwhile, the body of the mouse is easier to avoid, and the abdomen of the mouse is not easy to be blocked by the splint 18 to interfere with the anatomical operation. However, the clip 11 of the second embodiment is easy to interfere with the operation of clamping the neck of the rat when it is extended, and as the volume of the dissected rat increases, the clip 11 of the second embodiment needs to be longer, and the interference with the process of clamping the neck of the rat is greater. At the same time, the installation of the cylinders 28 takes up more space under the chassis 1, so that the equipment becomes more bulky and the cost of the equipment is higher.
The functions and implementation procedures not described in this embodiment are the same as those in the first embodiment, so that redundant description is omitted.
The above two embodiments are merely illustrative of many embodiments of the present invention, and many variations are possible without departing from the principles of the present invention, which would be within the scope of the invention. The terms "front", "rear", "upper", "lower" and the like in the present invention do not refer to absolute orientations and are to be understood in conjunction with the written description of the present invention and the drawings herein.

Claims (8)

1. A murine experimental dissecting table, comprising:
the chassis (1), the said chassis (1) is placed horizontally;
the chassis (1) is provided with a clamping device which is convenient for clamping the neck of the mouse so as to kill the mouse by using a neck dislocation method, and the chassis (1) is provided with a fixing device which is used for rapidly fixing the limbs of the mouse after the mouse is killed;
the clamping device comprises a fixed block (2) fixedly arranged on a chassis (1), a supporting plate (3) for supporting the neck of a mouse is fixedly arranged on the side wall of the fixed block (2), a first sliding block (4) capable of sliding along the left and right directions of the chassis (1) is slidably arranged on the chassis (1), a first spring (5) is horizontally arranged between the first sliding block (4) and the fixed block (2), a rotating plate (6) is rotatably arranged on the first sliding block (4), a limiting block (7) for limiting the rotation angle of the rotating plate (6) is arranged on the sliding block, a pressing part matched with the supporting plate (3) to clamp the neck of the mouse is fixedly arranged on the rotating plate (6), a handle (8) is rotatably arranged on the side wall of the chassis (1), a notch (9) is formed in the handle (8), a pin shaft (10) is fixedly arranged on the rotating plate (6), the pin shaft (10) penetrates through the notch (9), and a device for conveniently adjusting the direction of the rotation of the chassis (1) in the horizontal direction.
The fixing device comprises two rectangular frame-shaped clips (11) which are rotatably arranged on a rotating plate (6) and used for clamping four limbs of a mouse, the two clips (11) are symmetrically arranged on the left side and the right side of a supporting plate (3), each clip (11) is provided with a torsion spring (12), each torsion spring (12) enables the clip (11) to keep a trend of being attached to the rotating plate (6), a limiting module used for temporarily limiting the clip (11) is arranged beside each clip (11), and an adjusting device used for adjusting the strength of the mouse when the mouse is killed is further arranged on the rotating plate (6) above the clip (11).
2. A murine experimental dissecting table according to claim 1, characterized in that: the rotating device comprises a base (13) arranged below the chassis (1), a gear (14) is horizontally and fixedly arranged below the chassis (1), the turntable is rotatably arranged on the base (13) and can rotate on the base (13), and a bolt (15) for positioning the gear (14) is horizontally and slidably arranged on the side wall of the base (13).
3. A murine experimental dissecting table according to claim 1, characterized in that: the pressing part comprises a reed (16) fixedly arranged on the rotating plate (6) and opposite to the supporting plate (3) and used for clamping the back neck of the mouse, the reed (16) is in a herringbone shape, and two bifurcated ends of the reed (16) are bent towards the direction of the rotating plate (6).
4. A murine experimental dissecting table according to claim 3, characterized in that: the outer surface of the reed (16) is uniformly wrapped with a soft layer (17).
5. A murine experimental dissecting table according to claim 1, characterized in that: the front end of each clip (11) is obliquely and fixedly provided with a clamping plate (18) for hooking the mouse claw, and each clamping plate (18) is provided with wavy teeth for conveniently clamping the mouse claw.
6. A murine experimental dissecting table according to claim 5, characterized in that: every all fixed mounting has a plurality of claw that are used for stirring the mouse so that clip (11) can more stably clip plectrum (19) of mouse claw on clip (11), and is a plurality of connect about plectrum (19) and arrange full clip (11), every plectrum (19) all are parallel with splint (18), every plectrum (19) all are closer the pivot of clip (11) than splint (18), every the length of plectrum (19) all is greater than the width of splint (18).
7. A murine experimental dissecting table according to claim 1, characterized in that: the adjusting device comprises a second spring (20) which is arranged at one end of the rotating plate (6) away from the rotating point and is parallel to the surface of the rotating plate (6) and is convenient for adjusting the strength of the broken mouse cervical vertebra, a hook (21) is arranged at one end of the second spring (20) close to the pressing part, a sliding groove (22) is formed in the rotating plate (6), a second sliding block (29) is slidably arranged on the sliding groove (22), and a clamp (23) for fixing the tail of the mouse is arranged on the sliding block.
8. A murine experimental dissecting table according to claim 7, characterized in that: the limiting module comprises a lock body (24) fixedly arranged on the rotating plate (6), a lock tongue (25) used for clamping the clip (11) is slidably arranged in the lock body (24), a spring III (26) is arranged between the lock tongue (25) and the lock body (24), the spring III (26) always keeps the lock tongue (25) extending out of the lock body (24), a steel wire (27) is fixedly arranged at one end of the lock tongue (25) located in the lock body (24), and the steel wire (27) penetrates through the lock tongue (25) and is connected to a slider II (29).
CN202310112817.7A 2023-02-14 2023-02-14 Laboratory dissecting table for murine animals Active CN115869100B (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105517607A (en) * 2013-08-05 2016-04-20 曼金德公司 Insufflation apparatus and methods
CN110786956A (en) * 2019-11-19 2020-02-14 浙江大学医学院附属妇产科医院 Mouse euthanasia operation device

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105517607A (en) * 2013-08-05 2016-04-20 曼金德公司 Insufflation apparatus and methods
CN110786956A (en) * 2019-11-19 2020-02-14 浙江大学医学院附属妇产科医院 Mouse euthanasia operation device

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