CN115869042A - Thrombus taking device - Google Patents

Abstract

The invention relates to a thrombus taking device. The thrombus taking device comprises a near-end support, a middle support and a far-end support, wherein the near-end support, the middle support and the far-end support are sequentially arranged from a near end to a far end, the middle support comprises a first connecting rod and a second connecting rod which are arranged at intervals, the near end of the first connecting rod is connected with the near-end support, the far end of the second connecting rod is connected with the far-end support, and the first connecting rod and the second connecting rod extend in a similar circumferential curve on the circumferential surface of the thrombus taking device. The utility model provides a thrombectomy device, because first connecting rod and second connecting rod class circumference curve extend on thrombectomy device's global for can be along the class circumference direction bending of first connecting rod, second connecting rod and be close to between near-end support, the distal end support, make thrombectomy device whole have the shape of similar spiral extension from the near-end to the distal end, improve thrombectomy device crooked performance. When the thrombus taking device is positioned in a bent blood vessel, the shape similar to the spiral extension can be bent and deformed to well conform to the bent blood vessel, and the thrombus taking device 30 can be tightly attached to the inner wall of the bent blood vessel, so that thrombus is effectively prevented from falling off.

Description

Thrombus taking device

Technical Field

The invention relates to the field of medical instruments, in particular to a thrombus removal device.

Background

Acute Ischemic Stroke (AIS), commonly known as cerebral infarction, is a nerve tissue injury caused by ischemic necrosis of local brain tissue due to sudden obstruction of blood flow in the brain. Acute ischemic stroke is the most common type of stroke and is the main disease causing death and disability in the middle-aged and elderly. Especially acute cerebral apoplexy caused by great vessel occlusion, the disease condition is dangerous, and the death rate and disability rate are high. Once stroke occurs, great physical and psychological harm is caused to the patient, and heavy burden is also caused to the family and the society of the patient.

At present, the clinical treatment of cerebral arterial thrombosis mainly adopts mechanical thrombus removal. The mechanical thrombus taking is to convey a thrombus taking device to a lesion position, grasp the thrombus by the thrombus taking device and take the thrombus out of the body. However, the existing thrombus taking instrument has poor bending performance, and at the part of a human body with bent blood vessels, the thrombus taking instrument cannot be tightly attached to the inner walls of the blood vessels, so that the thrombus is easy to fall off.

Disclosure of Invention

Therefore, there is a need for a thrombus removal device that can conform well to a curved blood vessel, can closely adhere to the inner wall of the curved blood vessel, and effectively prevent thrombus from falling off.

The thrombus removal device comprises a thrombus removal device, the thrombus removal device comprises a near-end support, a middle support and a far-end support which are sequentially arranged from a near end to a far end, the middle support comprises a first connecting rod and a second connecting rod which are arranged at intervals, the near end of the first connecting rod is connected with the near-end support, the far end of the second connecting rod is connected with the far-end support, and the first connecting rod and the second connecting rod are in circumferential similar circumferential curve extension of the thrombus removal device.

A virtual connecting line exists between the far end of the first connecting rod and the near end of the second connecting rod on the circumferential surface of the embolectomy device, and the first connecting rod, the virtual connecting line and the second connecting rod can form a spiral line surrounding the longitudinal central axis of the embolectomy device.

The number of the first connecting rods is two, the number of the second connecting rods is two, a virtual connecting line exists between one of the first connecting rods and one of the second connecting rods, a virtual connecting line also exists between the other one of the first connecting rods and the other one of the second connecting rods, the first connecting rod, the virtual connecting line between the first connecting rod and the second connecting rod form two spiral lines surrounding the longitudinal central shaft of the embolectomy device, and the two spiral lines are not connected with each other.

The middle support comprises a first capturing part, the first capturing part and the first connecting rod are adjacently arranged on the circumferential surface of the embolectomy device, the near end of the first capturing part is fixedly connected with the near end support, and the far end of the first capturing part is suspended.

The first catching part comprises a first sub-catching piece and a second sub-catching piece, the first sub-catching piece and the second sub-catching piece are arranged on the peripheral surface of the bolt taking device at intervals, the first connecting rod is arranged between the first sub-catching piece and the second sub-catching piece, and the projections of the first sub-catching piece and the second sub-catching piece on at least one plane containing the longitudinal central axis of the bolt taking device are partially overlapped.

The middle support further comprises a second capturing part, the second capturing part and the first capturing part are sequentially arranged from the near end to the far end, the near end of the second capturing part is fixedly connected with the far end of the first connecting rod, the far end of the second capturing part is suspended, and projections of the far end of the second capturing part and the far end of the first capturing part on a plane perpendicular to the longitudinal central axis of the embolectomy device are spaced from each other.

The middle support further comprises a third capturing part, the far end of the third capturing part is suspended, the first capturing part, the third capturing part and the second capturing part are sequentially arranged in the direction from the near end to the far end, the near end of the third capturing part is connected with the first connecting rod, the far end of the third capturing part is adjacent to the second connecting rod, and at least two adjacent projections of the far end of the first capturing part, the far end of the third capturing part and the far end of the second capturing part on a plane perpendicular to the longitudinal central axis of the bolt extractor are spaced from each other.

The middle support further comprises a third connecting rod, the third connecting rod is connected between the first connecting rod and the second connecting rod, and the third connecting rod and the second connecting rod extend along a circumferential curve on the circumferential surface of the embolectomy device.

A first virtual connecting line exists between the far end of the first connecting rod and the near end of the third connecting rod on the circumferential surface of the embolectomy device, a second virtual connecting line also exists between the far end of the third connecting rod and the near end of the second connecting rod on the circumferential surface of the embolectomy device, and the first connecting rod, the first virtual connecting line, the third connecting rod, the second virtual connecting line and the second connecting rod can form a spiral line surrounding the longitudinal central shaft of the embolectomy device.

And parts of the first connecting rods and parts of the second connecting rods are parallel to each other.

The utility model provides a thrombectomy device, because first connecting rod and second connecting rod class circumference curve extend on thrombectomy device's global for can be along the class circumference direction bending of first connecting rod, second connecting rod and be close to between near-end support, the distal end support, make thrombectomy device whole have the shape of similar spiral extension from the near-end to the distal end, improve thrombectomy device crooked performance. When the thrombus extractor is positioned in a bent blood vessel, the thrombus extractor can be bent and deformed like a shape extending spirally, so that the thrombus extractor can well conform to the bent blood vessel, and the thrombus extractor can be tightly attached to the inner wall of the bent blood vessel to effectively prevent thrombus from falling off.

Drawings

Fig. 1 is a structural schematic view of an embolectomy device provided by a first embodiment of the application in fig. 1, which is used for capturing thrombus in a human blood vessel.

Fig. 2 is a schematic cross-sectional view of a thrombus removal device provided in a first embodiment of the present application in a natural state.

Fig. 3 is a schematic cross-sectional structural view of a thrombus removal device provided by a first embodiment of the application in a compressed state.

Fig. 4 is a schematic perspective view of the embolectomy device in the first embodiment of the present application.

Fig. 5 is a perspective view of another angle embolectomy device in the first embodiment of the present application.

Fig. 6 is a schematic deployment view of the embolectomy device of the first embodiment of the present application.

Fig. 7 is an enlarged schematic view at X in fig. 6.

Fig. 8 is an enlarged schematic view of XX in fig. 6.

Fig. 9 is a schematic cross-sectional view of a thrombectomy device according to a second embodiment of the present application.

Fig. 10 is a schematic cross-sectional view of a embolectomy device in a second embodiment of the present application.

Fig. 11 is a schematic cross-sectional view of a thrombus removal device provided by a third embodiment of the present application.

Fig. 12 is a schematic view of an elastic member according to a third embodiment of the present application.

Fig. 13 is a schematic cross-sectional view of a thrombectomy device according to a fourth embodiment of the present application.

Fig. 14 is a schematic cross-sectional view of a thrombectomy device according to a fourth embodiment of the present application.

FIG. 15 is a schematic cross-sectional view of a embolectomy device provided in a fifth embodiment of the present application.

Fig. 15a is an enlarged schematic view of fig. 15 a.

Fig. 16 is a cross-sectional view of a piercing member of a thrombectomy device according to a fifth embodiment of the present application.

FIG. 17 is a cross-sectional view of a lancet at another angle in a embolectomy device as provided in a fifth embodiment of the present application.

FIG. 18 is a schematic cross-sectional view of a embolectomy device of a sixth embodiment of the present application.

Fig. 19 is a schematic structural view of an elastic member in a embolectomy device provided by a sixth embodiment of the present application.

Fig. 20 is a schematic structural view of an elastic member in a embolectomy device provided in a seventh embodiment of the present application.

Detailed Description

In order to make the aforementioned objects, features and advantages of the present invention comprehensible, embodiments accompanied with figures are described in detail below. In the following description, numerous specific details are set forth in order to provide a thorough understanding of the present invention. This invention may, however, be embodied in many different forms and should not be construed as limited to the embodiments set forth herein, but rather should be construed as broadly as the present invention is capable of modification in various respects, all without departing from the spirit and scope of the present invention.

Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. The terminology used in the description of the invention herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention.

In the field of interventional medical devices, the "distal end" is defined as the end that is distal from the operator during the procedure, and the "proximal end" is defined as the end that is proximal to the operator during the procedure. "axial" refers to a direction parallel to the line connecting the center of the distal end and the center of the proximal end of the medical device, and "radial" refers to a direction perpendicular to the axial direction.

In an embodiment of the invention, the "radial force" refers to the force required to deform the medical device in the radial direction. Wherein the smaller the acting force required to deform the medical device in the radial direction, the smaller the radial force, the easier the medical device is to compress or expand radially toward the central axis; the greater the force required to deform the medical device in the radial direction, the greater the radial force, and the more difficult it is for the medical device to compress or expand radially toward the central axis.

First embodiment

Referring to fig. 1 to 3, fig. 1 is a schematic structural view illustrating a thrombus capture device in a human blood vessel according to a first embodiment of the present application; fig. 2 is a schematic cross-sectional view of a thrombus removal device provided in a first embodiment of the present application in a natural state. Fig. 3 is a schematic cross-sectional structural view of a thrombus removal device provided by a first embodiment of the application in a compressed state. Wherein, the structure of the bolt taking device in both figure 2 and figure 3 is simplified.

In this embodiment, the thrombectomy device 1 comprises a microcatheter 10, a push-pull wire 20, a thrombectomy device 30, a visualization ring 40, and an elastic member 50. The micro catheter 10 has a hollow tubular structure, the micro catheter 10 accommodates the push-pull wire 20 and the embolectomy device 30, and the micro catheter 10 is used for delivering the embolectomy device 30 to the thrombus 200 of the blood vessel 100 and releasing the embolectomy device 30. The distal end of the push-pull wire 20 is fixedly connected with the proximal end of the embolectomy device 30, and the push-pull wire 20 can slide in the microcatheter 10 and drive the whole embolectomy device 30 to slide relative to the microcatheter 10.

Referring to fig. 4 to 6, fig. 4 is a schematic perspective view of a bolt extractor in a first embodiment of the present application; FIG. 5 is a perspective view of another embodiment of the present application; fig. 6 is a schematic deployment view of the embolectomy device of the first embodiment of the present application. In this embodiment, the embolectomy device 30 may be formed by laser cutting a metal tube (e.g., a NiTi alloy tube) having shape memory effect and superelasticity, then forming the tube by a die, and then heat-treating the tube to shape. Alternatively, the embolectomy device 30 may be formed by cutting a metal sheet having shape memory effect and superelasticity, then molding the cut metal sheet by a mold, and then performing heat treatment for shaping. Alternatively, the embolectomy device 30 may be formed by weaving a wire having shape memory effect and superelasticity, and then molding with a mold and heat-treating to shape. Alternatively, the embolectomy device 30 may be made of a highly elastic polymer material. Suitable materials mentioned above are well known to those skilled in the art and will not be described in detail here.

In this embodiment, the embolectomy device 30 is a self-expanding stent structure. The embolectomy device 30 includes a proximal stent 31, a middle stent 32, and a distal stent 33, which are arranged in this order from the proximal end to the distal end. The middle bracket 32 is connected between the proximal bracket 31 and the distal bracket 33. The middle bracket 32 is located in the middle portion of the unitary embolectomy device 30. In this embodiment, the proximal bracket 31, the middle bracket 32 and the distal bracket 33 are integrally formed. The proximal stent 31 is used to support an integral central stent 32 and distal stent 33. The middle stent 32 is used to capture thrombus. The distal stent 33 is used to furl the thrombus and prevent the thrombus from falling off. In other embodiments, the proximal support 31, the middle support 32, and the distal support 33 may be different components, based on the support that can be fixedly connected to form a whole among the proximal support 31, the middle support 32, and the distal support 33.

In this embodiment, the middle bracket 32 includes a first link 324 and a second link 325 spaced apart from each other. The proximal end of the first link 324 is connected to the proximal bracket 31. The distal end of the second link 325 is connected to the distal bracket 33. The first link 324 and the second link 325 extend in a circumferential-like curve on the circumferential surface of the embolectomy device 30. The circumferential curve-like extension means that the curved extension is similar to the curved extension along the circumferential direction on the circumferential surface of the embolectomy device 30, and the extending direction of the curved extension is not parallel to the direction of the longitudinal central axis of the embolectomy device 30, and is not along the circumferential direction of the embolectomy device 30. Curvilinear extensions include one or more of arcs, polylines, straight lines, and the like. Due to the design, the first connecting rod 324 and the second connecting rod 325 extend along the circumferential-like curve on the circumference of the embolectomy device 30, so that the proximal bracket 31 and the distal bracket 33 can be bent and approached along the circumferential-like direction of the first connecting rod 324 and the second connecting rod 325, the embolectomy device 30 integrally has a shape extending like a spiral from the proximal end to the distal end, and the bending performance of the embolectomy device 30 is improved. When the thrombus taking device 30 is positioned in a bent blood vessel, the shape similar to the spiral extension can be bent and deformed to well conform to the bent blood vessel, and the thrombus taking device 30 can be tightly attached to the inner wall of the bent blood vessel, so that thrombus is effectively prevented from falling off.

The structures of the proximal stent 31, the middle stent 32, and the distal stent 32 of the embolectomy device 30 will be explained in detail below. Referring to fig. 6, the proximal stent 31 includes a first supporting rod 311 and a first grid unit 312 distributed in sequence. The proximal ends of the first supporting rods 311 converge at the proximal end of the proximal stent 31, the other parts of the first supporting rods 311 extend outwards, and the distal ends of the first supporting rods are connected with the distal ends of the first grid cells 312. In the present embodiment, the first support bar 311 is integrally formed with the first grid unit 312. The bar width of the first support bar 311 is 0.1mm-0.5mm. Wherein, the rod width refers to the length between the two endpoints that are farthest away. In this embodiment, the number of the first supporting rods 311 is two, and the two first supporting rods 311 are symmetrically distributed about the central axis of the embolectomy device 30, so that the external acting force is uniformly and symmetrically transmitted to the first grid unit 312 and the middle bracket 32 of the embolectomy device 30 through the two first supporting rods 311. In other embodiments, the number of the first support rods 311 is one.

Referring to fig. 6 and 7, fig. 7 is an enlarged schematic view of the point X in fig. 6. The first support bar 311 has a bar width that is greater than the bar width of the entire embolectomy device 30 at various other locations, i.e., the bar width of the first support bar 311 is greatest. Specifically, the first support bar 311 has a wider bar than the central holder 32, and the first support bar 311 has a wider bar than the distal holder 33. The rigidity of the first support rod 311 is greater than the rigidity of the embolectomy device 30 at different positions, the first support rod 311 is more difficult to deform than other different parts of the embolectomy device 30, and the shape of the first support rod 311 can be kept unchanged while the external acting force is effectively transmitted to other different positions of the embolectomy device 30.

In the present embodiment, the rod width of the first support rod 311 gradually increases in the direction from the distal end to the proximal end in the axial direction, and the greater the rigidity of the first support rod 311, the more difficult it is to deform. Due to the design, the part of the first support rod 311 close to the proximal end has higher rigidity and is not easy to bend, so that the first support rod 311 is prevented from bending to influence the recovery of the embolectomy device 30.

In this embodiment, the first lattice unit 312 in the proximal stent 31 is symmetrical about the central axis of the embolectomy device 30, and the first lattice unit 312 can uniformly receive the force transmitted through the push-pull wire 20 and the first support rod 311, so that the radial support force of the proximal stent 31 can be ensured after the proximal stent 31 is released from the micro-catheter 10. In other embodiments, the first lattice unit 312 in the proximal stent 31 may not be symmetrical about the central axis of the embolectomy device 30, so as to ensure the radial support force of the proximal stent 31.

As for the middle bracket 32. In the present embodiment, the middle bracket 32 includes a first catching portion 321, a second catching portion 322, a third catching portion 323, a first link 324, a second link 325, and a third link 326. The first catching portion 321, the second catching portion 322, and the third catching portion 323 are arranged in this order from the proximal end to the distal end. The first link 324, the third link 326, and the second link 325 are arranged in order from the proximal end to the distal end. In fig. 6, the first catching portion 321 is provided between two adjacent first lattice units 312 in the proximal stent 31.

The proximal end of the first link 324 is fixedly connected to the first grid unit 312 at the distal end of the proximal stent 31. In this embodiment, the first link 324 is fixedly connected to the converging portion of the first grid unit 312 at the distal end. In other embodiments, the first link 324 can also be fixedly connected to the non-converging portion of the first wire rod unit 312.

In this embodiment, the distal end of the first link 324 is fixedly connected to the second catch portion 322. In the present embodiment, the number of the first links 324 is two, and the two first links 324 are disposed oppositely. A proximal end of the third link 326 is fixedly connected to the second catch portion 322 and a distal end of the third link 326 is fixedly connected to the third catch portion 323. The proximal end of the second link 325 is fixedly connected to the third catching portion 323, and the distal end of the second link 325 is fixedly connected to the distal bracket 33.

In this embodiment, the first catch portion 321 and the second catch portion 322 only partially coincide in projection perpendicular to a plane including the longitudinal central axis of the embolectomy device 30. And the distal ends of the first capturing portion 321 and the second capturing portion are spaced from each other in projection on a plane perpendicular to the plane containing the longitudinal central axis of the embolectomy device. Due to the design, thrombus can be captured by the embolectomy device 30 at different positions on the peripheral surface of the embolectomy device, so that the capturing effect of the embolectomy device 30 is improved. Specifically, referring to fig. 6, a part of the first link 324 is bent obliquely with respect to the positive direction of the X-axis on the circumferential surface of the plug remover 30. In other embodiments, the first link 324 may be bent obliquely in other directions on the circumference of the embolectomy device 30, so as to improve the capturing effect of the embolectomy device 30.

In the present embodiment, the first link 324, the third link 326 and the second link 325 are axially spaced from the proximal end to the distal end. The first link 324, the third link 326, and the second link 325 are each arc-shaped and extend like a circumferential curve on the circumferential surface of the plug remover 30. Of the distal ends of the first catching portion 321, the third catching portion 323 and the second catching portion 322, projections of the distal ends of at least two adjacent catching portions on a plane perpendicular to the longitudinal central axis of the embolectomy device are spaced from each other, so that the embolectomy device 30 can catch thrombus at different positions on the circumferential surface thereof at the same time, thereby improving the catching effect of the embolectomy device 30. In other embodiments, the distal ends of at least adjacent two of the distal ends of the first catching portion 321, the third catching portion 323, and the second catching portion 322 are all spaced apart in projection on a plane perpendicular to the central axis of the longitudinal direction of the embolectomy device, so that the positions of the distal ends of the first catching portion 321, the third catching portion 323, and the second catching portion 322 on the circumferential surface of the embolectomy device 30 are further staggered, thereby improving the catching effect of the embolectomy device 30.

Compared with the case of the connecting rods which are parallel along the axial direction, in the embodiment, the first connecting rod 324, the third connecting rod 326 and the second connecting rod 325 extend on the peripheral surface of the thrombus remover 30 in a similar circumferential curve, so that the first connecting rod 324, the third connecting rod 326 and the second connecting rod 325 have good bending deformation capability in the axial direction, the proximal stent 31, the middle stent 32 and the distal stent 33 are easy to bend mutually, the proximal stent 31, the middle stent 32 and the distal stent 33 can well adhere to the bent blood vessel 100 in the process of passing through the bent blood vessel 100, and thrombus is prevented from being separated from the thrombus remover 30 because the thrombus remover 30 does not adhere to the inner wall of the blood vessel 100.

Specifically, in fig. 6, the first link 324, a part of the third link 326 and a part of the second link 325 are bent to be inclined downward along the circumferential surface of the bolt lifter 30 with respect to the positive direction of the X-axis, in other embodiments, the first link 324, the third link 326 and the second link 325 may also be bent to be inclined in different or partially same directions along the circumferential surface of the bolt lifter 30, so as to achieve better bending performance of the bolt lifter 30.

In the present embodiment, a portion of the first link 324 and a portion of the third link 326 are parallel to each other. The fact that the portions of the first link 324 and the third link 326 are parallel to each other means that the portions of the first link 324 and the third link 326 are parallel to each other, and the portions of the first link 324 and the third link 326 are not parallel to each other. Specifically, in the present embodiment, the third connecting rod 326 includes a straight section 3261 and an inclined section 3262. The angled section 3262 is parallel or approximately parallel to the first link 324. The straight section 3261 is not parallel to the first link 324, but is parallel to the X-axis. With such a design, the distance between the second catching portion 322 and the third catching portion 323 can be increased, the size of the opening between the second catching portion 322 and the third catching portion 323 can be increased, the entry of thrombus from the opening between the second catching portion 322 and the third catching portion 323 can be facilitated, and the thrombus catching performance of the thrombus catcher 30 can be improved.

In the present embodiment, a portion of the first link 324, a portion of the second link 325, and a portion of the third link 326 are parallel to each other, so that the proximal bracket 31 and the distal bracket 33 are easily bent and extended in the same direction. The fact that a portion of the first link 324, a portion of the second link 325, and a portion of the third link 326 are parallel means that a portion of the first link 324, a portion of the second link 325, and a portion of the third link 326 are parallel, and at the same time, at least a portion of the first link 324, the second link 325, and the third link 326 are not parallel. In this embodiment, the second link 325 has an arch shape, a portion of the second link 325 is inclined upward in the positive direction of the X-axis, and the portion of the second link 325 is parallel or approximately parallel to the first link 324. With this arrangement, the distance between the first catching portion 321, the second catching portion 322 and the third catching portion 323 can be increased, the size of the opening of the first catching portion 321, the second catching portion 322 and the third catching portion 323 can be increased, the entry of thrombus from the opening between the first catching portion 321, the second catching portion 322 and the third catching portion 323 can be facilitated, and the thrombus catching performance of the embolectomy device 30 can be improved. In other embodiments, portions of first link 324, second link 325, and third link 326 may be approximately parallel to each other to allow proximal bracket 31 and distal bracket 33 to easily extend in the same direction.

There is a virtual connection line between the distal end of the first link 324 and the proximal end of the second link 325 on the circumference of the embolectomy device 30, and the first link 324, the virtual connection line and the second link 325 can form a spiral line around the longitudinal central axis of the embolectomy device 30, so that the embolectomy device 30 composed of the proximal stent 31 and the distal stent 33 can have a shape similar to a spiral extension and can be easily bent. In other embodiments, the first link 324, the imaginary line, and the second link 325 may form a curve around the longitudinal center axis of the embolectomy device 30 that may resemble the shape of a helix.

In the present embodiment, the number of the first links 324 is two, and two first links 325 are disposed opposite to each other. Accordingly, the second link 325 and the third link 326 are respectively provided in two numbers and are opposed to each other.

A virtual line exists between one of the first links 324 and one of the second links 325. A virtual line also exists between the other first link 324 and the other second link 325. Thus, the first connecting rod 324, the virtual connecting line between the first connecting rod 324 and the second connecting rod 325 form two spiral lines around the longitudinal central axis of the embolectomy device, and the two spiral lines are not connected with each other. Two spiral lines are formed in the thrombus extractor 30, so that the bending deformation performance of the thrombus extractor 30 can be further improved, the thrombus extractor is easy to bend, better conforms to a bent blood vessel and is tightly attached to the inner wall of the bent blood vessel, and thrombus is effectively prevented from falling off. In other embodiments, the embolectomy device 30 may form only one helical line, which may allow the embolectomy device 30 to bend and deform in the helical direction of the helical line. In other embodiments, the embolectomy device 30 may form a helical line with 3 or more helical lines, particularly to achieve the effect that the embolectomy device 30 is easily bent and can closely fit the inner wall of a blood vessel.

In this embodiment, a first virtual connecting line 327 exists between the distal end of the first link 324 and the proximal end of the third link 326 on the circumferential surface of the embolectomy device 30, a second virtual connecting line 328 also exists between the distal end of the third link 326 and the proximal end of the second link 325 on the circumferential surface of the embolectomy device 30, and the first link 324, the first virtual connecting line 327, the third link 326, the second virtual connecting line 328, and the second link 325 may form a spiral line around the longitudinal central axis of the embolectomy device 30. The design enables the whole embolectomy device 30 composed of the proximal stent 31, the middle stent 32 and the distal stent 33 to have a shape similar to a spiral extension and to be easily bent.

In other embodiments, the mid-stent 32 may include only the first link 324 and the second link 325, subject to the embolectomy device 30 conforming well to the curved vessel 1000.

The shape of the first link 324, the shape of the second link 325, and the shape of the third link 326 will be described below. In the present embodiment, the first link 324 is inclined downward as a whole with respect to the positive X-axis direction. The second link 325 is partially inclined downward with respect to the positive direction of the X-axis. The portion of the second link 325 inclined with respect to the positive X-axis direction is parallel or approximately parallel to the first link 324. The second link 325 has a shape partially identical to that of the first link 324. The second link 325 is arched, and a portion of the second link 325 is inclined upward in the positive X-axis direction, and the portion of the second link 325 is parallel or approximately parallel to the first link 324. The other part of the second link 325 is inclined downward in the positive X-axis direction.

The third link 326 includes a straight section 3261 and an inclined section 3262. The proximal end of the straight section 3261 is fixedly connected to the second catch portion 322, the distal end of the straight section 3261 is fixedly connected to the proximal end of the inclined section 3262, and the distal end of the inclined section 3262 is fixedly connected to the third catch portion 323. The inclined section 3262 is parallel or approximately parallel to the first link 324, and the straight section 3261 extends in a direction parallel to the X-axis, so that the distance between the second catching portion 322 and the third catching portion 323 can be increased, the size of the opening between the second catching portion 322 and the third catching portion 323 can be increased, thrombus can enter from the opening between the second catching portion 322 and the third catching portion 323, and the thrombus catching performance of the thrombus catcher 30 can be improved.

The first connecting rod 324, the second connecting rod 325 and the third connecting rod 326 are partially identical in shape, which facilitates the arrangement of the positions of the proximal bracket 31, the middle bracket 32 and the distal bracket 33, so that the whole embolectomy device 30 can have good bending performance, and the arrangement of the whole structure of the embolectomy device 30 is ensured. In other embodiments, the shapes of the first link 324, the second link 325 and the third link 326 may be the same, based on the fact that the first link 324, the second link 325 and the third link 326 can achieve the overall cork extractor 30 with the tendency of extending spirally in the circumferential direction and better bending performance.

Referring to fig. 6 and 8, fig. 8 is an enlarged view of XX in fig. 6. Otherwise consistent, the greater rod width at the proximal end of the first link 324 than at the intermediate portion of the first link 324 may increase the strength of the first link 324 at the proximal end, making the proximal end of the first link 324 less likely to break than the intermediate portion of the first link 324. The distal end of the first link 324 is also wider than the middle portion of the first link 324, and the distal end of the first link 324 is less likely to break. Accordingly, the second connecting rod 325 and the third connecting rod 326 are similarly arranged, and are not described in detail herein.

In the present embodiment, the proximal end of the first link 324 is rounded to avoid the proximal end of the first link 324 from being easily broken due to stress concentration. The distal end of the first link 324, the proximal and distal ends of the second link 325, and the proximal and distal ends of the third link 326 are also rounded.

Referring to fig. 6 again, the rod width of the first link 324, the rod width of the second link 325, and the rod width of the third link 326 are all larger than the rod width of the net rod in the distal bracket 33, and the rod width of the first link 324, the rod width of the second link 325, and the rod width of the third link 326 are smaller than the rod width of the first support rod 311 in the proximal bracket 31, so that the strength of the first link 324, the second link 325, and the third link 326 is larger than the strength of the net rod in the distal bracket 33, and is smaller than the strength of the first support rod 311, so that the first link 324, the second link 325, and the third link 326 are easy to bend and deform, and have better strength and are not easy to break.

The first catching portion 321, the second catching portion 322, and the third catching portion 323 are described below. Referring again to fig. 4 to 6, the first catch portion 321 includes first and second sub-catches 3211, 3212 arranged at spaced intervals. The first and second sub-catches 3211 and 3212 each include two net rods, proximal ends of which are respectively connected to net rod portions of adjacent first net rod units, distal ends of which converge together, and portions of which converge are suspended. When the thrombus remover 30 is released in the blood vessel, the thrombus remover 30 is pressed by the blood vessel 100, and the proximal parts of the two net rods are radially compressed, so that the converged parts of the distal ends of the two net rods are expanded outwards, and the thrombus can be captured by the first capturing part. Accordingly, the second catching portion 322 and the third catching portion 323 are similar in shape to the first catching portion 321. The second catching part 322 and the third catching part 323 each comprise two catching pieces, each of which is enclosed by two net rods. The proximal ends of the net rods are fixedly connected with the net rod units in the middle bracket 32; the converged part of the far ends of the net rods is suspended.

In this embodiment, the projections of the first sub-catch 3211 and the second sub-catch 3212 in the first catch portion 321 onto at least one plane containing the longitudinal center axis of the embolectomy device 30 partially overlap. Specifically, a portion of the first sub-catch 3211 and a portion of the second sub-catch 3212 are aligned, with the distal end of the first sub-catch 3211 being spaced further from the proximal end of the embolectomy device 30 than the distal end of the second sub-catch 3212 is spaced further from the proximal end of the embolectomy device 30. During the process of the first capturing part 321 being retracted into the micro-catheter 10, the two opposite capturing pieces will not overlap each other while being compressed into the micro-catheter 10, so as to reduce the thickness of the first capturing part 321 during the process of being compressed into the micro-catheter 10, and facilitate the retraction of the first capturing part 321 into the micro-catheter 10. Accordingly, the two catches in the second catch portion 322 and the two catches in the third catch portion 323 also have similar shapes to the two catches in the first catch portion 321, respectively, subject to the ease of entry of the second and third catch portions 322, 323 into the microcatheter 10.

In the present embodiment, the distal ends of the first catching portions 321 are wound with development points, and the distal ends of the third catching portions 323 are also wound with development points, respectively. In other embodiments, the distal end of the second catch portion 322 may also be wrapped with a visualization point.

The structure of the distal stent 33 is described below. The distal stent 33 comprises a plurality of uniformly arranged grid cells. When the embolectomy device 30 is deployed, the lattice cells are approximately diamond-shaped, and adjacent lattice cells are connected to each other. The openings of the grid units of the far-end support 33 are smaller than those of the grid units in the middle support, and the far-end support 33 can intercept and contain thrombus in the thrombus taking device 30 to prevent the thrombus from falling off.

The elastic member 50 is described below. In this embodiment, the elastic member 50 extends into the interior of the embolectomy device 30, and the elastic member 50 is located in the space enclosed by the embolectomy device 30. The distal end of the elastic element 50 is fixedly connected with the distal end of the embolectomy device 30, and the proximal end of the elastic element 50 is fixedly connected with the proximal end of the embolectomy device 30. Specifically, as shown in FIG. 2, the proximal end of the embolectomy device 30 is covered by the proximal end of the elastic member 50. The visualization ring 40 wraps around the outer surface of the proximal end of the embolectomy device 30, securing the proximal end of the embolectomy device 30 to the proximal end of the elastic member 50. Accordingly, the distal end of the embolectomy device 30 is wrapped around the distal end of the resilient member 50. The developer ring 40 wraps around the outer surface of the distal end of the embolectomy device 30 to secure the distal end of the embolectomy device 30 to the distal end of the elastic member 50. The elastic member 50 is made of a metal material. The elastic member 50 extends spirally in the axial direction to form a spiral shape, so that it has elasticity.

In the present embodiment, the push-pull wire 20 is integrally formed with the elastic member 50. The sliding of the push-pull wire 20 on the micro-catheter 10 also causes the elastic member 50 to slide. In other embodiments, the push-pull wire 20 and the elastic member 50 are two different components, so that the push-pull wire 20 and the elastic member 50 can be fixedly connected.

In this embodiment, in the process of transforming the embolectomy device 1 from the natural state to the compressed state, the proximal end and the distal end of the embolectomy device 30 are far away from each other, the distance between the proximal end and the distal end of the embolectomy device 30 gradually increases, the embolectomy device 30 is entirely contracted in the radial direction, the embolectomy device 30 is entirely elongated in the axial direction, the distance between the proximal end and the distal end of the embolectomy device 30 increases, so that the elastic member 50 is deformed and axially stretched, at this time, the elastic member 50 has a restoring force for restoring the original shape, and the restoring force can make the distal end and the proximal end of the embolectomy device 30 approach each other, so as to prevent the embolectomy device 30 from extending too long in the axial direction. With reference to fig. 1 to 3, the operation process and the specific function of the elastic element 50 of the present embodiment are described as follows:

the microcatheter 10, and the embolectomy device 30 disposed within the microcatheter 10, are moved to a target location within the blood vessel 100. The thrombectomy device 30 is exposed outside the micro-catheter 10 such that the thrombectomy device 30 at least partially corresponds to the thrombus 200 on the inner wall of the blood vessel 100 in a radial direction. The thrombectomy device 30 expands under its own radial expansion force. At least a portion of the outer surface of the embolectomy device 30 contacts the thrombus 200 on the inner wall of the blood vessel 100, and a portion of the thrombus 200 is embedded in the embolectomy device 30. The push wire 20 is then operated to withdraw the embolectomy device 30 from the microcatheter 10, while the thrombus is drawn back into the catheter by the radially expansive force of the embolectomy device 30. Under the action of withdrawing the thrombus extractor 30, the proximal end of the thrombus extractor 30 moves towards the direction away from the distal end of the thrombus extractor 30, so that the thrombus extractor 30 contracts, and the distal end and the proximal end of the thrombus extractor 30 are close to each other due to the restoring force of the elastic piece 50, so that the distance between the proximal end of the thrombus extractor 30 and the distal end of the thrombus extractor 30 is prevented from being increased too much, the contraction degree of the thrombus extractor 30 in the radial direction is reduced, the thrombus extractor 30 can be ensured to be closely attached to the inner wall of the blood vessel 100, and the success rate of dragging the thrombus 200 into the micro-catheter 10 is improved. Further, the thrombus 200 enters the thrombus remover 30, and the spirally extending elastic member 50 increases the contact area with the thrombus 200, restricts the movement of the thrombus 200, prevents the thrombus 200 from falling, and improves the thrombus recovery ability of the thrombus remover 30.

Referring to fig. 3 again, when the bolt remover 30 is in a compressed state and the elastic element 50 is straightened, the restoring force of the elastic element 50 is maximum. The axial length of the resilient member 50 when straightened is equal to the maximum axial length between the proximal and distal ends of the embolectomy device 30.

Second embodiment

Referring to fig. 9 and 10, fig. 9 is a schematic cross-sectional view of a thrombus removal device according to a second embodiment of the present application; fig. 10 is a schematic cross-sectional view of a embolectomy device in a second embodiment of the present application. The embolectomy device 1a of this embodiment is substantially the same as the first embodiment, except that the elastic member 50a and the push-pull wire 20a are not integrally formed in this embodiment. The elastic member 50a has elasticity and is formed of a polymer material. The proximal end of the elastic member 50a is fixedly connected to the distal end of the push-pull wire 20 a. Specifically, the distal end of the push-pull wire 20a is provided with a fixing ring 21a, and the elastic member 50a is fixedly connected with the fixing ring 21 a. Specifically, the elastic member 50a is wound around the fixing ring 21a and is bound and fixed.

In this embodiment, the embolectomy device 1a further comprises a connecting ring 60a. The distal end of the attachment ring 60a is fixedly attached to the distal end of the embolectomy device 30 a. Specifically, the elastic member 50a and the connection ring 60a are wound and bound together. In this embodiment, the elastic member 50a may pass through the opening of the connection ring 30a and be bound and fixed to the connection ring 60a. The elastic piece 50a has elasticity, so that a spiral structure does not need to be formed in the axial direction to ensure the elasticity of the elastic piece 50a, and the arrangement can reduce the density of radial parts of the embolectomy device and is easier to sheath.

Third embodiment

Referring to fig. 11 and 12, fig. 11 is a schematic cross-sectional view of a thrombus removal device 1b according to a third embodiment of the present application; fig. 12 is a schematic view of an elastic member according to a third embodiment of the present application. The thrombectomy device 1b of the present embodiment is substantially the same as the first embodiment, except that in the present embodiment, the elastic member 50b comprises a flat section 51b and a spiral section 52b connected to the flat section 51 b. In the axial direction, the flat section 51a is directly opposite to the catching portion 320b of the middle bracket 32 b. Specifically, the catching portion 320b includes a first catching portion 321b, a second catching portion 322b, and a third catching portion 323b. The flat section 51a corresponds to the first catching portion 321b, the second catching portion 322b, and the third catching portion 323b in the bolt taker, respectively. The flat section 51a is flat and extends in the axial direction, so that mutual interference among the first catching portion 321b, the second catching portion 322b and the third catching portion 23b can be avoided, and the flat section 51a is prevented from winding around the first catching portion 321b, the second catching portion 322b and the third catching portion 23b to influence the deployment of the embolectomy device in the blood vessel. In other embodiments, the catching portion 320b may include only the first catching portion 321b, or only the first catching portion 321b and the second catching portion 322b, subject to the function that the catching portion 320b can catch thrombus.

In the present embodiment, the plurality of spiral sections 52b correspond to the proximal stent 31b and the distal stent 33b, respectively. The plurality of spiral segments 52b have restoring force after being stretched in the axial direction, ensuring elasticity of the overall elastic member 50 b. Meanwhile, the plurality of spiral sections 52b can increase the contact area with the thrombus, preventing the thrombus from falling off.

In the present embodiment, the flat section 51b is connected between two adjacent spiral sections 51b, so that the thrombus entering the corresponding flat section 51b part of the embolectomy device 30b is blocked by the adjacent spiral section 52b and is not easy to move, thereby improving the effect of the embolectomy device 30b in preventing the thrombus from falling off.

Fourth embodiment

Referring to fig. 13 and 14, fig. 13 is a schematic cross-sectional view of a thrombus removal device according to a fourth embodiment of the present application; fig. 14 is a schematic cross-sectional view of a thrombectomy device according to a fourth embodiment of the present application. The present embodiment provides a thrombectomy device 1c substantially the same as the first embodiment, except that in the present embodiment, the elastic member 50c comprises a main body 51c and a plurality of puncture members 52c fixedly connected with the main body 51 c. The body 51c extends in the axial direction. The plurality of piercing members 52c are spaced apart from each other in the main body 51c and are circumferentially staggered. In the process of capturing the thrombus, the single puncture element 52c can pierce the thrombus to fix the thrombus and prevent the thrombus from falling out of the thrombus extractor 30c. The plurality of puncture elements 52c can increase the contact area between the elastic member and the thrombus, and the plurality of adjacent puncture elements 52c can sandwich the thrombus, thereby further improving the effect of preventing the thrombus from falling.

In the present embodiment, the angle between each of the puncture elements 52c and the main body 51c in the axial direction is an acute angle, and in conjunction with fig. 13, the extending direction of the main body is parallel to the extending direction of the X-axis. The angle between each of the puncture elements 52c and the main body in the axial direction is an acute angle, which is the same as the angle between each of the puncture elements 52c and the positive direction of the X-axis. When the thrombus remover 30c is compressed into the microcatheter 10c, the puncture piece 52c can approach the main body 51c clockwise from the point of connection with the main body 51c as a base point, so as to smoothly enter the microcatheter 10c, thereby ensuring that the microcatheter 10c smoothly recovers the thrombus and the thrombus remover 30c. The piercing member 52c is easily pushed against the inner wall of the micro-catheter 10c or held at the nozzle of the micro-catheter 10c to prevent the thrombus removal device 30c from entering the micro-catheter when the angle between the piercing member 52c and the positive direction of the X-axis is obtuse.

Fifth embodiment

Referring to fig. 15 to 17, fig. 15 is a schematic cross-sectional view of a thrombus extractor of a thrombus extraction device according to a fifth embodiment of the present application; FIG. 16 is a cross-sectional view of a spike in a embolectomy device provided in a fifth embodiment of the present application;

FIG. 17 is a cross-sectional view of a lancet at another angle in a embolectomy device as provided in a fifth embodiment of the present application. The embolectomy device 1d according to this embodiment is basically the same as the fourth embodiment, except that in this embodiment, the puncture piece 52d is fitted to the outer surface of the main body 51 d. Specifically, the puncture element 52d is fitted to the outer surface of the main body 51d through its opening, and the puncture element 52d is compressed to reduce the opening of the puncture element 52d, thereby preventing the puncture element 52d from falling off.

In the present embodiment, the main body 51d is provided with a housing groove 53d. The partial puncture element 52d is accommodated in the accommodation groove 53d, and the partial puncture element 52d is axially restricted by the inner wall of the accommodation groove 53d, so that the puncture element 52d can rotate only around the outer surface of the main body 51 d. The puncture piece 52d can increase the contact area with thrombus, improve the effect of capturing thrombus and the effect of preventing thrombus from falling off, and the puncture piece 52d can rotate in compliance with the bending of the blood vessel, thereby avoiding puncturing the inner wall of the blood vessel.

Sixth embodiment

Referring to fig. 18, fig. 18 is a schematic cross-sectional view of a thrombus extractor of a thrombus extraction device according to a sixth embodiment of the present application; fig. 19 is a schematic structural view of an elastic member in a embolectomy device provided by a sixth embodiment of the present application. The thrombectomy device 1e provided in this embodiment is substantially the same as the thrombectomy device 1e provided in the first embodiment, except that, in this embodiment, the elastic member 50e includes a first helical line 51e and a second helical line 52e, and the first helical line 51e and the second helical line 52e are wound and extended mutually. The proximal end of the first helical wire 51e is tightly attached to and wound around the proximal end of the second helical wire 52e, and then is fixedly connected to the distal end of the push-pull wire 20e and the proximal end of the embolectomy device 30 e. In a natural state, the distal end of the first spiral line 51e is tightly attached to and wound around the distal end of the second spiral line 52e, and then is fixedly connected to the distal end of the embolectomy device 30 e. The main body portion of the first helical line 51e (except for the proximal end of the first helical line and the distal end of the first helical line) and the main body portion of the second helical line 52e (except for the proximal end of the second helical line and the distal end of the second helical line) extend helically in the axial direction, and have a gap therebetween, and together enclose an accommodating space.

In the thrombus taking process, the elastic piece can limit the axial extension of the thrombus taking device 30e to be overlong, and can increase the contact area with the thrombus in the thrombus taking process, so that part of the thrombus can be embedded into the accommodating space between the first spiral line 51e and the second spiral line 52e, the thrombus is supported by the first spiral line 51e and the second spiral line 52e and cannot be easily separated, and the thrombus is prevented from falling off.

Referring to fig. 20, fig. 20 is a schematic structural view of an elastic member in a thrombus removal device according to a seventh embodiment of the present application. The embolectomy device in this embodiment is substantially the same as the embolectomy device in the sixth embodiment. In contrast, the elastic member 50e includes a plurality of spiral lines 53e. The plural number means three or more. The proximal ends of the plurality of helical wires 53e are tightly wound and fixedly connected to the distal end of the push-pull wire 20 e. The distal ends of the plurality of helical wires 53e are tightly wound and fixedly attached to the distal end of the embolectomy device 30 e. The helical wires 53e include body portions connected to the proximal ends and the distal ends thereof, and the body portions are received in the embolectomy device 30e, extend helically with respect to each other, and intersect each other to define a receiving space 54e. The thrombus entering the housing space 54e is stopped by the plurality of spiral lines 53e and is hard to escape. And a plurality of the spiral lines 53e are mutually matched with the thrombus extractor 30e, and the thrombus is clamped between the thrombus extractor 30e and the plurality of the spiral lines 53e, so that the thrombus is effectively prevented from falling off.

The technical features of the embodiments described above may be arbitrarily combined, and for the sake of brevity, all possible combinations of the technical features in the embodiments described above are not described, but should be considered as being within the scope of the present specification as long as there is no contradiction between the combinations of the technical features.

The above-mentioned embodiments only express several embodiments of the present invention, and the description thereof is more specific and detailed, but not construed as limiting the scope of the invention. It should be noted that various changes and modifications can be made by those skilled in the art without departing from the spirit of the invention, and these changes and modifications are all within the scope of the invention. Therefore, the protection scope of the present patent should be subject to the appended claims.

Claims (10)

1. The utility model provides a thrombectomy device, its characterized in that, thrombectomy device is including thrombectomy ware, thrombectomy ware includes near-end support, middle part support and the distal end support that sets gradually from near-end to distal end, the middle part support includes first connecting rod and the second connecting rod of interval arrangement, the near-end of first connecting rod with near-end leg joint, the distal end of second connecting rod with distal end leg joint, first connecting rod with the second connecting rod is in class circumference curve extension on thrombectomy ware global.

2. The embolectomy device of claim 1 wherein a virtual line exists between the distal end of the first link and the proximal end of the second link on the circumference of the embolectomy device, and the first link, the virtual line, and the second link form a helix about the longitudinal central axis of the embolectomy device.

3. The embolectomy device of claim 1 wherein the number of the first links is two, the number of the second links is two, one virtual line exists between one of the first links and one of the second links, one virtual line also exists between the other of the first links and the other of the second links, the first link, the virtual line between the first link and the second link, and the second link form two helical lines around the longitudinal central axis of the embolectomy device, and the two helical lines are not connected to each other.

4. The embolectomy device of claim 1, wherein the middle support comprises a first catch portion, the first catch portion is arranged adjacent to the first link on the circumference of the embolectomy device, a proximal end of the first catch portion is fixedly connected to the proximal support, and a distal end of the first catch portion is suspended.

5. The embolectomy device of claim 4, wherein the first capturing portion comprises a first sub-capturing member and a second sub-capturing member, the first sub-capturing member and the second sub-capturing member being spaced apart on a circumferential surface of the embolectomy device, the first link being disposed between the first sub-capturing member and the second sub-capturing member, and projections of the first sub-capturing member and the second sub-capturing member on at least one plane including a longitudinal center axis of the embolectomy device partially overlap.

6. The embolectomy device of claim 4, wherein the central support further comprises a second capturing portion disposed sequentially from a proximal end to a distal end of the first capturing portion, the proximal end of the second capturing portion is fixedly connected to the distal end of the first link, the distal end of the second capturing portion is suspended, and projections of the distal end of the second capturing portion and the distal end of the first capturing portion on a plane perpendicular to a longitudinal central axis of the embolectomy device are spaced apart from each other.

7. The embolectomy device of claim 6, wherein the central scaffold further comprises a third capturing portion, a distal end of the third capturing portion is suspended, the first capturing portion, the third capturing portion and the second capturing portion are arranged in a proximal-to-distal direction, a proximal end of the third capturing portion is connected to the first link, a distal end of the third capturing portion is adjacent to the second link, and at least two adjacent distal ends of the first capturing portion, the third capturing portion and the second capturing portion are spaced from each other in a projection perpendicular to a plane containing a longitudinal central axis of the embolectomy device.

8. The embolectomy device of claim 1, wherein the middle support further comprises a third link connected between the first link and the second link, the third link extending like a circumferential curve on the circumference of the embolectomy device.

9. The embolectomy device of claim 8, wherein a first virtual line exists on the circumference of the embolectomy device between the distal end of the first link and the proximal end of the third link, and a second virtual line also exists on the circumference of the embolectomy device between the distal end of the third link and the proximal end of the second link, and the first link, the first virtual line, the third link, the second virtual line, and the second link may form a helix around the longitudinal central axis of the embolectomy device.

10. The embolectomy device of claim 1, wherein a portion of the first link and a portion of the second link are parallel to each other.

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