CN115779267A - Neural regulation and control system and wearable neural regulation and control device - Google Patents

Abstract

The invention relates to the technical field of medical instruments and discloses a nerve regulation and control system which comprises an information acquisition module, an adjustment control module, a nerve stimulation module and a system interaction module, wherein the information acquisition module, the adjustment control module and the nerve stimulation module are in communication connection through a data bus, and the system interaction module is in wireless communication connection with the information acquisition module, the adjustment control module and the nerve stimulation module through a wireless communication technology. According to the nerve regulation system and the wearable nerve regulation device, the brain electricity stimulation electrode is controlled to discharge through the brain electricity stimulation circuit, weak current is transmitted to the brain in a non-invasive mode, neuron excitation or inhibition is formed, a nerve network mode is adjusted, the nerve activity of a wake-sleep cycle is intervened specifically, and the sleep quality is improved.

Description

Neural regulation and control system and wearable neural regulation and control device

Technical Field

The invention relates to the technical field of medical instruments, in particular to a nerve regulation and control system and a wearable nerve regulation and control device.

Background

The brain is an organ composed of hundreds of billions of neurons, the neurons form an interwoven neural network, information is transmitted and integrated among the neural networks through membrane potential distribution of the neurons, and brain waves in a sleeping state are different from brain waves in a normal waking state. With the development of scientific technology, the non-invasive brain stimulation scheme aiming at sleep regulation has more and more prominent advantages in the research of improving sleep. The most widely used nerve stimulation technology is transcranial electrical stimulation tDCS which can be used for enhancing LTP and inhibiting LTD for a long time and enhancing neural plasticity, so that the nerve activity is regulated by physical stimulation, and the aim of improving sleep is fulfilled. DCS equipment, however, is heavy and expensive and is not widely used. Therefore, a need to be solved in clinic has been proposed for the shortcomings of current medical equipment, such as high monitoring environment requirement, high analysis technical requirement, high cost, and use in and out of hospital: the novel scientific and advanced sleep monitoring and regulation integrated solution replaces the prior art.

Therefore, a nerve regulation system and a wearable nerve regulation device are provided.

Disclosure of Invention

In order to make up for the defects of the prior art, the invention provides the following technical scheme: a nerve regulation and control system comprises an information acquisition module, an adjustment control module, a nerve stimulation module and a system interaction module, wherein the information acquisition module, the adjustment control module and the nerve stimulation module are in communication connection through a data bus, and the system interaction module is in wireless communication connection with the information acquisition module, the adjustment control module and the nerve stimulation module through a wireless communication technology;

the information acquisition module detects and records the brain wave activity during sleeping;

the adjustment control module analyzes the brain wave activity data collected by the information acquisition module and extracts the features of the brain waves during sleeping;

the nerve stimulation module stimulates the target nerve and changes brain waves by releasing micro current to the target nerve;

the system interaction module is integrated into a mobile phone APP, and data in the information acquisition module, the adjustment control module and the nerve stimulation module are checked and adjusted through the APP.

Preferably, the information acquisition module comprises historical electroencephalogram data, a real-time electroencephalogram acquisition unit and electroencephalogram acquisition electrodes, the historical electroencephalogram data comprises all electroencephalogram data which are acquired and recorded and stored in the past, the real-time electroencephalogram acquisition unit acquires, processes and records electroencephalograms in real time by setting interval time, and the electroencephalogram acquisition electrodes acquire the electroencephalograms by contacting with the skin of the head.

Preferably, the electroencephalogram acquisition electrode is made of one of silver, silver chloride, stainless steel or gold, the electroencephalogram acquisition electrode can directly contact with the scalp, a conductive adhesive is not needed during use, the acquired signal is an electric signal of 10uV magnitude, the signal acquired by the electroencephalogram acquisition electrode is an analog electric signal, the digital signal is finally output after amplification, analog filtering and A/D conversion of a digital acquisition unit in the real-time electroencephalogram acquisition unit, and the digital signal is finally transmitted to the system interaction module.

Preferably, the adjustment control module comprises a physiological index monitoring unit, a preprocessing unit, an electroencephalogram feature extraction unit and a mode identification unit, the physiological index monitoring unit is used for measuring heart rate, blood pressure, body temperature and respiratory frequency, the preprocessing unit preprocesses data acquired by the information acquisition module and the physiological index monitoring unit, and the mode identification unit carries out mode identification on processed brain waves based on the information acquisition module so as to identify different sleep stages.

Preferably, the nerve stimulation module comprises an electroencephalogram stimulation electrode, a safety isolation unit and an electroencephalogram stimulation circuit, the electroencephalogram stimulation electrode is made of silver or silver chloride, the electroencephalogram stimulation electrode can be in direct contact with the scalp, conductive glue is not needed to be applied when the nerve stimulation module is used, the safety isolation unit is used for reducing the current interference of other modules on the electroencephalogram stimulation electrode and the electroencephalogram stimulation circuit, meanwhile, the safety isolation unit is also used for reducing the current interference between the electroencephalogram stimulation electrode and the electroencephalogram stimulation circuit, and the electroencephalogram stimulation circuit outputs constant current to be transmitted to the electroencephalogram stimulation electrode, so that the electroencephalogram stimulation electrode generates electrical stimulation to a brain discharge point.

Preferably, the system interaction module comprises a window unit, a key unit and a voice unit, the window unit, the key unit and the voice unit are integrated in the mobile phone APP, the window unit displays corresponding data of each module and virtual keys of the key module through a mobile phone display screen, and the window unit, the key unit and the voice unit interact with a system user based on at least one mode of video, keys and voice.

Preferably, the physiological index monitoring unit comprises a plurality of physiological index monitoring devices, and the plurality of physiological index monitoring devices of the physiological index monitoring unit detect items including but not limited to heart rate, blood pressure, body temperature and respiratory rate.

Preferably, the electroencephalogram stimulation circuit comprises a boosting circuit and a constant current source circuit, the boosting circuit is mainly used for converting a 3.3V power supply into a 12V power supply required by the constant current source circuit, the constant current source circuit can output a constant current, and the constant current is transmitted to the electroencephalogram stimulation electrode, so that the electroencephalogram stimulation electrode generates electrical stimulation to a brain discharge point.

A wearable neuromodulation device comprising a flexible helmet and a neuromodulation system according to any of claims 1 to 8.

Preferably, the inside fixed mounting of flexible helmet has brain electricity collection electrode and brain electricity stimulating electrode, the top fixedly connected with equipment box of flexible helmet, brain electricity collection electrode and brain electricity stimulating electrode set up the inside at the flexible helmet in proper order in turn, be provided with information acquisition module, adjustment control module and nerve stimulation module in the equipment box.

Advantageous effects

Compared with the prior art, the invention provides a nerve regulation and control system and a wearable nerve regulation and control device, which have the following beneficial effects:

1. this neural regulation and control system and wearable neural regulation and control device carries out the real-time collection and the record of brain electricity through real-time brain electricity collection unit and brain electricity collection electrode to carry out data processing through the preprocessing unit among the adjustment control module, realize the real-time supervision to the brain electricity activity in the sleep, compare with the data of physiological index monitoring unit in order to confirm the stage everywhere of sleep and the quality of sleep through the mode identification module.

2. The nerve regulation and control system and the wearable nerve regulation and control device monitor the electroencephalogram during sleep through the information acquisition module and the adjustment control module, control the discharge of an electroencephalogram stimulation electrode through an electroencephalogram stimulation circuit after the sleep quality is reduced and the electroencephalogram generates abnormal fluctuation, transmit weak current to the brain through a non-invasive mode, penetrate a skull barrier from the outside of the skull to stimulate the cerebellum apical nucleus area in an atraumatic mode, stimulate the cranium to start an inherent nerve protection mechanism, improve the blood circulation of the brain and improve the sleep quality.

3. This neural regulation and control system and wearable neural regulation and control device, through wearing flexible helmet at the head, fix with fixing band, make flexible helmet portable, facilitate the use, can be treated at home, it detects collection and amazing adjustment to the brain electricity respectively to gather electrode and brain electricity through brain electricity, window unit in the interactive module of while system, button unit and speech unit set are in cell-phone APP, and through the video, at least one mode in button and the pronunciation is mutual with the system user, make the user can know the sleep condition of directly perceived self.

Drawings

FIG. 1 is a schematic diagram of the system of the present invention;

FIG. 2 is a first schematic structural diagram of a control device according to the present invention;

FIG. 3 is a schematic structural diagram of a second embodiment of the regulating device of the present invention;

fig. 4 is a brain wave band frequency table.

In the figure: 100. an information acquisition module; 101. historical electroencephalogram data; 102. a real-time electroencephalogram acquisition unit; 103. an electroencephalogram acquisition electrode; 200. adjusting the control module; 201. a physiological index monitoring unit; 202. a pre-processing unit; 203. an electroencephalogram feature extraction unit; 204. a pattern recognition unit; 300. a nerve stimulation module; 301. an electroencephalogram stimulation electrode; 302. a safety isolation unit; 303. an electroencephalogram stimulation circuit; 400. a system interaction module; 401. a window unit; 402. a key unit; 403. a voice unit; 501. a flexible helmet; 502. an equipment box; 503. and (5) fixing the binding band.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

Referring to fig. 1 to 3, a neural regulation system includes an information acquisition module 100, an adjustment control module 200, a neural stimulation module 300 and a system interaction module 400, wherein the information acquisition module 100, the adjustment control module 200 and the neural stimulation module 300 are in communication connection through a data bus, and the system interaction module 400 is in wireless communication connection with the information acquisition module 100, the adjustment control module 200 and the neural stimulation module 300 through a wireless communication technology;

the information acquisition module 100 detects and records the brain wave activity during sleeping;

the adjustment control module 200 analyzes the brain wave activity data collected by the information collection module 100 and performs feature extraction on the brain waves during sleep;

the nerve stimulation module 300 stimulates the craniocerebra to start an inherent nerve protection mechanism by releasing micro current to the targeted nerve to change brain waves;

the system interaction module 400 is integrated as a mobile phone APP, and checks and adjusts data in the information acquisition module 100, the adjustment control module 200, and the neurostimulation module 300 through the APP.

As an embodiment of the invention, the information acquisition module 100 comprises historical brain wave data 101, a real-time brain wave acquisition unit 102 and brain wave acquisition electrodes 103, wherein the historical brain wave data 101 comprises all brain wave data which are acquired and recorded and stored before, the real-time brain wave acquisition unit 102 acquires, processes and records brain waves in real time through set interval time, and the brain wave acquisition electrodes 103 acquire brain waves through contact with the skin of the head.

As an embodiment of the present invention, the electroencephalogram acquisition electrode 103 is made of one of silver, silver chloride, stainless steel or gold, the electroencephalogram acquisition electrode 103 can directly contact the scalp, when in use, no conductive adhesive is needed, the acquired signal is an electrical signal of 10uV magnitude, the signal acquired by the electroencephalogram acquisition electrode 103 is an analog electrical signal, and after amplification, analog filtering and a/D conversion of a digital acquisition unit in the real-time electroencephalogram acquisition unit 102, the signal is finally output as a digital signal, and the digital signal is finally transmitted to the system interaction module 400 for a professional of a doctor to check and judge.

As an embodiment of the present invention, the adjustment control module 200 includes a physiological index monitoring unit 201, a preprocessing unit 202, an electroencephalogram feature extraction unit 203, and a pattern recognition unit 204, the physiological index monitoring unit 201 measures heart rate, blood pressure, body temperature, and respiratory frequency, the preprocessing unit 202 preprocesses data acquired by the information acquisition module 100 and the physiological index monitoring unit 201, particularly electroencephalogram data, specifically, may perform low-pass filtering on an original electroencephalogram data wave signal of an original wave, extract a frequency band of 0 to 300Hz, for example, may perform filtering by using a second-order butterworth filter, so as to filter noise, the electroencephalogram feature extraction unit 203 performs fourier transform or wavelet decomposition, i.e., wavelet decomposition, on the original wave processed by the preprocessing unit 202, so as to decompose the original wave into 5 types of bands of general electroencephalogram, details of the bands are shown in fig. 4, the pattern recognition unit 204 performs pattern recognition on the processed electroencephalogram based on the information acquisition module 100, so as to perform real-time acquisition and recording on the electroencephalogram acquisition unit 102 and the electroencephalogram acquisition electrode 103, and performs real-time acquisition and recording on the processed electroencephalogram data by the preprocessing unit 202, and realizes real-time sleep quality comparison of the electroencephalogram data in the sleep-monitoring unit 201, and the sleep quality recognition of the electroencephalogram data.

As an implementation mode of the invention, the nerve stimulation module 300 comprises an electroencephalogram stimulation electrode 301, a safety isolation unit 302 and an electroencephalogram stimulation circuit 303, the electroencephalogram stimulation electrode 301 is made of silver or silver chloride and other materials, the electroencephalogram stimulation electrode 301 can directly contact scalp, conductive glue is not needed to be coated when the nerve stimulation module is used, the safety isolation unit 302 is used for reducing current interference of other modules on the electroencephalogram stimulation electrode 301 and the electroencephalogram stimulation circuit 303, meanwhile, the safety isolation unit 302 is also used for reducing current interference between the electroencephalogram stimulation electrode 301 and the electroencephalogram stimulation circuit 303, the electroencephalogram stimulation circuit 303 comprises a booster circuit and a constant current source circuit, the booster circuit is mainly used for converting a 3.3V power supply into a 12V power supply required by the constant current source circuit, the constant current source circuit can output constant current which is transmitted to the brain electricity stimulating electrode 301, so that the brain electricity stimulating electrode 301 generates electrical stimulation to a brain point, the brain electricity during sleeping is monitored through the information acquisition module 100 and the adjustment control module 200, when the sleeping quality is reduced and abnormal fluctuation of the brain electricity is generated, the brain electricity stimulating electrode 301 is controlled to discharge through the brain electricity stimulating circuit 303, weak current is transmitted to the brain non-invasively, the brain is stimulated to start an inherent nerve protection mechanism, the brain blood circulation is improved, a nerve network is adjusted, the nerve activity of a wake-sleep cycle is specifically intervened, and the sleeping quality is improved.

As an embodiment of the present invention, the system interaction module 400 includes a window unit 401, a key unit 402, and a voice unit 403, the window unit 401, the key unit 402, and the voice unit 403 are integrated in the mobile phone APP, the window unit 401 displays corresponding data of each module and virtual keys of the key module through a mobile phone display screen, and the window unit 401, the key unit 402, and the voice unit 403 interact with a system user based on at least one of video, key, and voice.

As an embodiment of the present invention, the physiological index monitoring unit 201 includes a plurality of physiological index monitoring devices, and the plurality of physiological index monitoring device detection items of the physiological index monitoring unit 201 include, but are not limited to, heart rate, blood pressure, body temperature, and respiratory rate.

A wearable neuromodulation device comprising a flexible helmet 501 and a neuromodulation system according to any of claims 1 to 8.

As an embodiment of the present invention, an electroencephalogram acquisition electrode 103 and an electroencephalogram stimulation electrode 301 are fixedly installed inside a flexible helmet 501, an equipment box 502 is fixedly connected to the top of the flexible helmet 501, the electroencephalogram acquisition electrode 103 and the electroencephalogram stimulation electrode 301 are sequentially and alternately arranged inside the flexible helmet 501, an information acquisition module 100, an adjustment control module 200 and a neurostimulation module 300 are arranged in the equipment box 502, the flexible helmet 501 is worn on the head and is fixed by a fixing strap 503, electroencephalogram is detected, collected and stimulated and adjusted by the electroencephalogram acquisition electrode 103 and the electroencephalogram stimulation electrode 301, a window unit 401, a key unit 402 and a voice unit 403 in a system interaction module 400 are integrated in a mobile phone APP, and interact with a system user by at least one of video, key and voice, so that the user can clearly and intuitively know the sleep condition of the user.

It is noted that, herein, relational terms such as first and second, and the like may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus.

Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Finally, it should be noted that: the above embodiments are only used to illustrate the technical solution of the present invention, and not to limit the same; while the invention has been described in detail and with reference to the foregoing embodiments, it will be understood by those skilled in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some or all of the technical features may be equivalently replaced; and the modifications or the substitutions do not make the essence of the corresponding technical solutions depart from the scope of the technical solutions of the embodiments of the present invention.

Claims (10)

1. A nerve regulation and control system comprises an information acquisition module (100), a regulation and control module (200), a nerve stimulation module (300) and a system interaction module (400), and is characterized in that: the information acquisition module (100) and the adjustment control module (200) are in communication connection with the nerve stimulation module (300) through a data bus, and the system interaction module (400) is in wireless communication connection with the information acquisition module (100), the adjustment control module (200) and the nerve stimulation module (300) through a wireless communication technology;

the information acquisition module (100) detects and records brain wave activity during sleep;

the adjustment control module (200) analyzes brain wave activity data collected by the information acquisition module (100) and extracts the features of the brain waves during sleep;

the nerve stimulation module (300) stimulates the craniocerebra to start an inherent nerve protection mechanism by releasing microcurrent to the target nerve to change brain waves;

the system interaction module (400) is integrated into a mobile phone APP, and data in the information acquisition module (100), the adjustment control module (200) and the nerve stimulation module (300) are checked and adjusted through the APP.

2. The neuromodulation system as in claim 1, wherein: the information acquisition module (100) comprises historical electroencephalogram data (101), a real-time electroencephalogram acquisition unit (102) and electroencephalogram acquisition electrodes (103), the historical electroencephalogram data (101) comprises all electroencephalogram data which are acquired and recorded and stored before, the real-time electroencephalogram acquisition unit (102) acquires, processes and records electroencephalograms in real time through set time intervals, and the electroencephalogram acquisition electrodes (103) acquire the electroencephalograms through contact with head skins.

3. The neuromodulation system as in claim 2, wherein: the electroencephalogram acquisition electrode (103) is made of one of silver, silver chloride, stainless steel or gold, the electroencephalogram acquisition electrode (103) can be in direct contact with the scalp, conductive adhesive is not needed during use, the acquired signal is an electric signal with a magnitude of 10uV, the signal acquired by the electroencephalogram acquisition electrode (103) is an analog electric signal, the digital signal is finally output after amplification, analog filtering and A/D conversion of a digital acquisition unit in the real-time electroencephalogram acquisition unit (102), and the digital signal is finally transmitted to the system interaction module (400).

4. The neuromodulation system as in claim 1, wherein: the adjustment control module (200) comprises a physiological index monitoring unit (201), a preprocessing unit (202), an electroencephalogram feature extraction unit (203) and a mode identification unit (204), wherein the physiological index monitoring unit (201) is used for measuring heart rate, blood pressure, body temperature and respiratory frequency, the preprocessing unit (202) preprocesses data acquired by an information acquisition module (100) and the physiological index monitoring unit (201), and the mode identification unit (204) carries out mode identification on processed brain waves based on the information acquisition module (100) so as to carry out different sleep stages.

5. The neuromodulation system as in claim 1, wherein: the nerve stimulation module (300) comprises an electroencephalogram stimulation electrode (301), a safety isolation unit (302) and an electroencephalogram stimulation circuit (303), the electroencephalogram stimulation electrode (301) is made of silver or silver chloride, the electroencephalogram stimulation electrode (301) can be in direct contact with the scalp, conductive glue is not needed to be applied when the nerve stimulation module is used, the safety isolation unit (302) is used for reducing the current interference of other modules on the electroencephalogram stimulation electrode (301) and the electroencephalogram stimulation circuit (303), meanwhile, the safety isolation unit (302) is also used for reducing the current interference between the electroencephalogram stimulation electrode (301) and the electroencephalogram stimulation circuit (303), and the electroencephalogram stimulation circuit (303) outputs constant current to be transmitted to the electroencephalogram stimulation electrode (301) so that the electroencephalogram stimulation electrode (301) emits points to the brain to generate electrical stimulation.

6. The neuromodulation system as in claim 1, wherein: the system interaction module (400) comprises a window unit (401), a key unit (402) and a voice unit (403), the window unit (401), the key unit (402) and the voice unit (403) are integrated in a mobile phone APP, the window unit (401) displays corresponding data of each module and virtual keys of the key module through a mobile phone display screen, and the window unit (401), the key unit (402) and the voice unit (403) interact with a system user based on at least one mode of video, key and voice.

7. The neuromodulation system as in claim 4, wherein: the physiological index monitoring unit (201) comprises a plurality of physiological index monitoring devices, and the detection items of the physiological index monitoring devices of the physiological index monitoring unit (201) include but are not limited to heart rate, blood pressure, body temperature and respiratory rate.

8. The neuromodulation system as in claim 5, wherein: the brain electricity stimulating circuit (303) comprises a boosting circuit and a constant current source circuit, the boosting circuit is mainly used for converting a 3.3V power supply into a 12V power supply required by the constant current source circuit, the constant current source circuit can output a constant current, and the constant current is transmitted to the brain electricity stimulating electrode (301) so that the brain electricity stimulating electrode (301) can generate electricity stimulation to a brain point.

9. A wearable neuromodulation device, comprising: comprising a flexible helmet (501) and a neuromodulation system according to any of claims 1 to 8.

10. The wearable neuromodulation device of claim 9, wherein: the utility model discloses a flexible helmet (501) is characterized in that the inside fixed mounting of flexible helmet (501) has brain electricity collection electrode (103) and brain electricity stimulation electrode (301), the top fixedly connected with equipment box (502) of flexible helmet (501), brain electricity collection electrode (103) and brain electricity stimulation electrode (301) set up in the inside of flexible helmet (501) in turn, be provided with information acquisition module (100), adjustment control module (200) and nerve stimulation module (300) in equipment box (502).

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