CN115772456A

CN115772456A - Embryonic stem cell separator

Info

Publication number: CN115772456A
Application number: CN202211568727.0A
Authority: CN
Inventors: 解军; 金姗姗; 梁宇翔; 张潇; 余兆威; 王磊; 帅旗志; 刘志贞; 赵虹; 彭志伟; 赵陶然
Original assignee: Shanxi Medical University
Current assignee: Shanxi Medical University
Priority date: 2022-12-08
Filing date: 2022-12-08
Publication date: 2023-03-10

Abstract

The invention discloses an embryonic stem cell separation device, which comprises a base, wherein the bottom of the base is fixedly connected with a supporting plate, the top of the base is fixedly connected with an observation instrument, the top of the base is fixedly provided with a controller, the outer side of the controller is fixedly connected with a lead, the top of the base is fixedly provided with a running groove, a rotating ring is driven to rotate by rotating a handle, a rotating shaft is driven to rotate by the rotating ring, the rotating shaft drives a screw rod to rotate in a threaded hole in a connecting plate, the screw rod moves in the threaded hole to drive a push rod to move, the push rod is movably connected in a clamping seat on the inner side of a positioning plate, the push rod drives the positioning plate to move, the positioning plate is close to a culture dish in the running groove by moving of the positioning plate, the positioning plate can fix the culture dish in the running groove, and the effect of being suitable for fixing culture dishes of different specifications is achieved.

Description

Embryonic stem cell separator

Technical Field

The invention relates to the technical field of stem cell separation, in particular to an embryonic stem cell separation device.

Background

The stem cell is a highly undifferentiated cell, has the characteristics of unlimited proliferation, self-renewal and multidirectional differentiation, can be cultured, expanded and established in vitro, and can also be induced to differentiate into various tissue cells under proper conditions. The stem cells are generally distributed in animal bone marrow, blood, various organs and embryos, particularly the embryonic stem cells are most distributed and can be differentiated into various organ tissues at the most primitive stage, so that the stem cells have medical treatment and research values.

Current embryonic stem cell separator is at the in-process that uses, and structure and function singleness not only do not have the light supplementing function, can't make the culture solution in the culture dish be in the constant temperature state moreover, and then reduced the work efficiency when separating the operation to because the culture dish size difference of every stem cell, so need fix a position the processing to it before the separation to stem cell, otherwise can influence stem cell's normal separation.

An effective solution to the problems in the related art has not been proposed yet.

Disclosure of Invention

The present invention is directed to an embryonic stem cell isolation device, which overcomes the above-mentioned problems of the related art.

Therefore, the invention adopts the following specific technical scheme:

the utility model provides an embryonic stem cell separator, includes the base, the bottom fixedly connected with backup pad of base, the top fixedly connected with observation instrument of base, the top fixed mounting of base has the controller, the outside fixedly connected with wire of controller, the top fixed mounting of base has the operation groove, the heating plate is installed to the inside fixed connection in operation groove, the inside fixedly connected with heat conduction cotton in operation groove, the top fixedly connected with linkage plate of base, the outside swing joint of linkage plate has the handle, the outside fixedly connected with rolling circle of handle, the outside fixedly connected with pivot of rolling circle, the outside fixedly connected with screw rod of pivot, the screw hole has been seted up to the inside of linkage plate, the outside fixedly connected with catch bar of screw rod, the outside fixedly connected with reset spring of linkage plate, reset spring's outside fixedly connected with locating plate, the inboard fixedly connected with joint seat of locating plate, the bottom fixedly connected with L type pole of locating plate, the bottom fixedly connected with extrusion cover of L type pole, the outside fixedly connected with power socket of operation groove, the outside fixedly connected with elastic switch of power socket, the top fixedly connected with L type pole, the telescopic link of electric light board, the lift dish is connected with the lift electric light board.

Preferably, the supporting plates are symmetrically distributed at the bottom of the base, and one end of the lead, which is far away from the controller, is fixedly connected to the outer side of the heating sheet.

Preferably, the heating plates are symmetrically distributed inside the running groove, and the heat-conducting cotton is symmetrically distributed inside the running groove.

Preferably, one end of the screw rod, which is far away from the rotating shaft, is rotatably connected inside a threaded hole inside the connecting joint plate, and the return springs are symmetrically distributed on the outer side of the connecting joint plate.

Preferably, the positioning plate is movably connected to the outer side of the connecting plate through a return spring, and one end, far away from the screw rod, of the pushing rod is movably connected to the inner portion of the clamping seat.

Preferably, the number of the L-shaped rods and the extrusion covers is two, and the L-shaped rods and the extrusion covers are symmetrically distributed at the bottom of the positioning plate.

Preferably, the power supply seats are symmetrically distributed on the outer side of the operation groove, and the elastic switch and the extrusion cover are positioned on the same plane.

Preferably, the number of the electric telescopic rods is the same as that of the lifting rods, and the electric telescopic rods are electrically connected with the power supply seat.

Preferably, the controller is electrically connected with the LED lamp panel, and the culture dish is movably connected in the operation groove.

The beneficial effects of the invention are as follows: through the top fixedly connected with operation groove at the base, at this moment, use through the cooperation of controller with the wire, thereby make the inside heating plate circular telegram of operation groove, make its heating through heating plate circular telegram, the inside fixedly connected with heat conduction cotton of rethread operation groove, thereby heat treatment is carried out to inside culture dish, make its one always be in under the homothermal state, work efficiency when guaranteeing the separation operation, drive the rolling circle through rotating the handle and rotate, it is rotatory to drive the pivot through the rolling circle, at this moment the pivot drives the screw rod and rotates in the screw hole of linking inside board, at this moment the screw rod removes in the screw hole and can drive the catch bar and move, because catch bar swing joint is in the inboard joint seat of locating plate, at this moment the catch bar can drive the locating plate and move, the removal of locating plate is close to the inside culture dish of operation groove, at this moment the locating plate can fix the inside culture dish of operation groove, reached and be suitable for the effect of fixing the culture dish of different specifications, it can make the L type pole of its bottom remove to carry out the light filling rod and move through the cooperation of L type pole and use with the cooperation of extrusion cover, thereby make the lamp plate remove the lamp plate and make the LED electric power pole and make the lamp plate move and make the lamp plate move up and go back to the lamp plate and go on the lift of the culture dish of the lamp plate and make the LED that the lamp plate and go on the lift.

Drawings

In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings needed in the embodiments will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and it is obvious for those skilled in the art to obtain other drawings without creative efforts.

FIG. 1 is a schematic diagram of the general structure of an embryonic stem cell separation apparatus according to an embodiment of the present invention;

FIG. 2 is a schematic structural diagram between a controller and a running groove of an embryonic stem cell separating device according to an embodiment of the present invention;

FIG. 3 is a schematic diagram of the structure between the connecting plate and the positioning plate of the embryonic stem cell separating device according to the embodiment of the present invention;

FIG. 4 is a schematic structural diagram of the top of a power supply socket of an embryonic stem cell separation device according to an embodiment of the present invention;

FIG. 5 is an enlarged view of the structure A in FIG. 2 of an embryonic stem cell separating device according to an embodiment of the present invention;

FIG. 6 is an enlarged view of the structure at B in FIG. 1 of an embryonic stem cell separating apparatus according to an embodiment of the present invention.

In the figure:

1. a base; 2. a support plate; 3. an observation instrument; 4. a controller; 5. a wire; 6. an operation groove; 7. a heating plate; 8. heat conducting cotton; 9. a connector tile; 10. a handle; 11. rotating the ring; 12. a rotating shaft; 13. a screw; 14. a threaded hole; 15. a push rod; 16. a return spring; 17. positioning a plate; 18. a clamping seat; 19. an L-shaped rod; 20. an extrusion cover; 21. a power supply base; 22. an elastic switch; 23. an electric telescopic rod; 24. a lifting rod; 25. an LED lamp panel; 26. a culture dish.

Detailed Description

For further explanation of the various embodiments, the drawings which form a part of the disclosure and which are incorporated in and constitute a part of this specification, illustrate embodiments and, together with the description, serve to explain the principles of operation of the embodiments, and to enable others of ordinary skill in the art to understand the various embodiments and advantages of the invention, and, by reference to these figures, reference is made to the accompanying drawings, which are not to scale and wherein like reference numerals generally refer to like elements.

According to an embodiment of the present invention, there is provided an embryonic stem cell separating device.

Example one

As shown in fig. 1-6, an embryonic stem cell separation apparatus according to an embodiment of the present invention includes a base 1, a support plate 2 is fixedly connected to the bottom of the base 1, an observation instrument 3 is fixedly connected to the top of the base 1, a controller 4 is fixedly installed at the top of the base 1, a wire 5 is fixedly connected to the outside of the controller 4, a running groove 6 is fixedly installed at the top of the base 1, a heating plate 7 is fixedly connected to the inside of the running groove 6, the support plate 2 is symmetrically distributed at the bottom of the base 1, one end of the wire 5 away from the controller 4 is fixedly connected to the outside of the heating plate 7, a heat-conductive cotton 8 is fixedly connected to the inside of the running groove 6, the heating plate 7 is symmetrically distributed inside the running groove 6, the heat-conductive cotton 8 is symmetrically distributed inside the running groove 6, a connecting rod 9 is fixedly connected to the top of the base 1, a handle 10 is movably connected to the outside of the connecting rod 9, a rotating ring 11 is fixedly connected to the outside of the handle 10, a rotating shaft 12 is fixedly connected to the outside of the rotating ring 11, a screw 13 is fixedly connected to the outside of the rotating shaft 12 is fixedly connected to the outside of the connecting rod 9, a restoring spring 17 is connected to the inner side of the restoring plate, a restoring spring 17 is connected to the restoring plate 17, a restoring spring is connected to the restoring plate 16, a restoring spring, a restoring plate 16 is connected to the restoring plate, a restoring spring, a restoring plate 16.

Example two

As shown in fig. 1-6, according to an embodiment of the present invention, an L-shaped rod 19 is fixedly connected to the bottom of a positioning plate 17, an extrusion cover 20 is fixedly connected to the bottom of the L-shaped rod 19, two extrusion covers 20 are provided for the L-shaped rod 19, the L-shaped rod 19 and the extrusion cover 20 are symmetrically distributed on the bottom of the positioning plate 17, a power supply base 21 is fixedly connected to the outer side of the operating trough 6, the power supply base 21 is symmetrically distributed on the outer side of the operating trough 6, an elastic switch 22 is located on the same plane as the extrusion cover 20, an elastic switch 22 is fixedly connected to the outer side of the power supply base 21, an electric telescopic rod 23 is fixedly connected to the top of the power supply base 21, the electric telescopic rods 23 and the lifting rods 24 are equal in number, the electric telescopic rods 23 and the power supply base 21 are electrically connected, a lifting rod 24 is fixedly connected to the top of the electric telescopic rod 23, an LED lamp panel 25 is fixedly connected to the top of the lifting rod 24, a culture dish 26 is movably connected to the inside of the operating trough 6, the controller 4 is electrically connected to the LED lamp panel 25, and the culture dish 26 is movably connected to the inside of the operating trough 6.

To sum up, with the above technical solution of the present invention, the operation slot 6 is fixedly connected to the top of the base 1, and then the controller 4 is used in cooperation with the lead 5, so as to energize the heating plate 7 inside the operation slot 6, and energize the heating plate 7 to heat the same, and then the heat conductive cotton 8 is fixedly connected to the inside of the operation slot 6, so as to heat the inner culture dish 26, so that the inner culture dish is always in a constant temperature state, thereby ensuring the working efficiency during the separation operation, the rotating ring 11 is driven to rotate by rotating the handle 10, the rotating shaft 12 is driven to rotate by the rotating ring 11, the rotating shaft 12 drives the screw 13 to rotate in the threaded hole 14 inside the connecting plate 9, at this time, the screw 13 moves in the threaded hole 14 to drive the push rod 15 to move, because the push rod 15 is movably connected to the bayonet socket 18 inside the positioning plate 17, at this time, the push rod 15 drives the positioning plate 17 to move, the positioning plate 17 moves close to the culture dish 26 inside the operation slot 6, at this time, the positioning plate 17 moves close to the culture dish 26 inside the lamp plate 17, and the positioning plate 17 moves up through the electric switch, and the positioning plate 21 moves, so as to move, when the positioning plate 21 moves away from the lamp plate 21 and the lamp plate 21 moves, and the lamp plate 21 moves upward, thereby, the power supply base 21 is powered off, the LED lamp panel 25 returns to the original position, and the culture dish 26 is conveniently taken out.

The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents, improvements and the like that fall within the spirit and principle of the present invention are intended to be included therein.

Claims

1. The embryonic stem cell separating device is characterized by comprising a base (1), a bottom fixedly connected with supporting plate (2) of the base (1), a top fixedly connected with observation instrument (3) of the base (1), a controller (4) fixedly mounted at the top of the base (1), an outer fixedly connected with wire (5) of the controller (4), a running groove (6) fixedly mounted at the top of the base (1), a heating sheet (7) installed at the inner fixed connection of the running groove (6), heat-conducting cotton (8) fixedly connected with the inner part of the running groove (6), a top fixedly connected with connecting plate (9) of the base (1), a handle (10) movably connected with the outer side of the connecting plate (9), a rotating ring (11) fixedly connected with the outer side of the handle (10), a rotating shaft (12) fixedly connected with the outer side of the rotating ring (11), a screw rod (13) fixedly connected with the outer side of the rotating shaft (12), a threaded hole (14) formed in the connecting plate (9), an outer side fixed connection of the screw rod (15) of the screw rod (13), a reset spring (16) fixedly connected with the outer side of the reset spring (16) of the reset spring (17), inboard fixedly connected with joint seat (18) of locating plate (17), the bottom fixedly connected with L type pole (19) of locating plate (17), the bottom fixedly connected with extrusion housing (20) of L type pole (19), the outside fixedly connected with power socket (21) of operation groove (6), the outside fixedly connected with elastic switch (22) of power socket (21), the top fixedly connected with electric telescopic handle (23) of power socket (21), the top fixedly connected with lifter (24) of electric telescopic handle (23), the top fixedly connected with LED lamp plate (25) of lifter (24), the inside swing joint of operation groove (6) has culture dish (26).

2. The embryonic stem cell separating device as claimed in claim 1, wherein the supporting plates (2) are symmetrically distributed at the bottom of the base (1), and one end of the lead (5) far away from the controller (4) is fixedly connected to the outer side of the heating plate (7).

3. The embryonic stem cell separation device according to claim 1, wherein the heating plates (7) are symmetrically distributed inside the running groove (6), and the heat-conducting cotton (8) is symmetrically distributed inside the running groove (6).

4. The device for separating embryonic stem cells according to claim 1, wherein one end of the screw (13) far from the rotating shaft (12) is rotatably connected to the inside of the threaded hole (14) inside the connecting plate (9), and the return springs (16) are symmetrically distributed on the outer side of the connecting plate (9).

5. The device for separating embryonic stem cells as claimed in claim 1, wherein the positioning plate (17) is movably connected to the outer side of the connecting plate (9) through a return spring (16), and the end of the pushing rod (15) far away from the screw rod (13) is movably connected to the inside of the clamping seat (18).

6. The embryonic stem cell separating device as claimed in claim 1, wherein the number of the L-shaped rods (19) and the extrusion covers (20) is two, and the L-shaped rods (19) and the extrusion covers (20) are symmetrically distributed at the bottom of the positioning plate (17).

7. The device for separating embryonic stem cells as claimed in claim 1, wherein the power supply seats (21) are symmetrically distributed outside the running groove (6), and the elastic switch (22) and the extrusion cover (20) are positioned on the same plane.

8. The device for separating embryonic stem cells as claimed in claim 1, wherein the number of the electric telescopic rods (23) and the number of the lifting rods (24) are the same, and the electric telescopic rods (23) are electrically connected with the power supply base (21).

9. The embryonic stem cell separating device as claimed in claim 1, wherein the controller (4) is electrically connected with the LED lamp panel (25), and the culture dish (26) is movably connected inside the running groove (6).