CN115737185A - Mouse fixer for mouse tail vein injection - Google Patents
Mouse fixer for mouse tail vein injection Download PDFInfo
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- CN115737185A CN115737185A CN202211294951.5A CN202211294951A CN115737185A CN 115737185 A CN115737185 A CN 115737185A CN 202211294951 A CN202211294951 A CN 202211294951A CN 115737185 A CN115737185 A CN 115737185A
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Abstract
The invention discloses a mouse fixer for mouse tail vein injection, which comprises a base, wherein a groove is formed in the base, a fixer body is arranged on the groove, a tail support mounting groove is formed in the base between the groove and the edge of the base, a tail support is mounted in the tail support mounting groove, a tail support fixing groove is formed in the upper surface of the tail support, a mouse inlet and a mouse outlet are formed in one side of the fixer body, a first strip-shaped through groove is formed in the top surface of the fixer body, a second strip-shaped through groove is formed in the side wall of the fixer body, and a mouse fixing seat is arranged in the fixer body; compared with the existing portable mouse tail vein injection fixing instrument, the portable mouse tail vein injection fixing instrument is more advanced and humanized, and the success rate of mouse tail vein injection of researchers, particularly zero-experience researchers, is improved; the invention is equivalent to other portable mouse tail vein injection fixing instruments in cost, has stronger market competitiveness and obtains better market benefit.
Description
Technical Field
The invention relates to the technical field of mouse tail vein injection, in particular to a mouse fixer for mouse tail vein injection.
Background
Mouse tail vein injection is an important experimental technology in animal experiments, and currently, many fields (particularly biology and medicine) need to carry out drug or cell injection modeling through mouse tail veins. However, the tail vein of the mouse is very thin, the injection operation is extremely difficult, and especially, the injection operation is a very challenging task for some researchers or college students who just start to contact the animal experiment and model the tail vein of the mouse. Moreover, failure of the first needle injection often results in wasted injected drug or engineered cells, decreased welfare of the mice, or the subcutaneous injection resulting in tail swelling that is not amenable to a second tail vein injection.
The portable mouse tail vein injection fixing instrument of the prior art has the advantages that the base and the mouse fixer are integrated and can not be disassembled, the mouse can be fixed in the instrument only in a prone position, and the prior mouse tail vein injection fixing instrument has the following defects:
1. the mouse can only lie prone in the fixator, the tail needs to be rotated by 90 degrees clockwise or anticlockwise during tail vein injection, needle insertion and injection are carried out through the tail vein on the side edge, and the difficulty in keeping the needle head and the tail vein horizontal is increased after rotation;
2. the tail of the mouse needs to be straightened and kept horizontal by a researcher, shaking is easy to occur during needle insertion and injection, and the difficulty of tail vein injection is increased due to the fact that a needle head is easy to puncture;
3. the height of the base is not adjustable.
Disclosure of Invention
The invention aims to: in order to solve the problems of a mouse tail vein injection fixing instrument, the mouse fixing device for mouse tail vein injection is particularly provided, a mouse is fixed to keep a side position, veins on two sides of a tail are horizontally positioned right below the line of sight of research, needle insertion and injection are facilitated, and smooth and efficient modeling of mouse tail vein injection by zero-base workers is facilitated.
The purpose of the invention is realized by the following technical scheme:
the utility model provides a mouse fixer for mouse tail vein injection, includes the base, set up the recess on the base, be equipped with the fixer body on the recess, the tail stock mounting groove has been seted up between recess and the base edge, install the tail stock in the tail stock mounting groove, the tail stock upper surface is equipped with the tail fixed slot, the one side that the tail stock mounting groove was kept away from to the fixer body is equipped with the mouse access & exit, the top surface of fixer body is equipped with first bar logical groove along the length direction of fixer body, the lateral wall that the fixer body is close to the tail stock mounting groove is equipped with the second bar and leads to the groove along the direction of height of fixer body, first bar leads to the groove and communicates each other between the groove with the second bar, this internal mouse fixing base that is equipped with of fixer, and the axis is horizontal toper through-hole has been seted up at the middle part of mouse fixing base, the aperture of toper through-hole is along the direction that is close to the tail stock mounting groove crescent, the top of mouse fixing base is equipped with clamping screw, the upper end of clamping screw runs through first bar and leads to the groove and stretches out the fixer body outward, clamping screw can freely move along the length direction that the groove in first bar leads to lead to the inslot, clamping screw is equipped with the fixed nut of adaptation.
In the above scheme, the length, width, the height of base are 150mm, 120mm, 8mm respectively, and the length, width, the degree of depth of recess are 121mm, 31mm, 5mm respectively, and the length, width, the degree of depth of tail stock mounting groove are 10mm, 5mm respectively, the external diameter of fixer body: the length is 120mm, the width is 30mm, and the height is 30mm; inner diameter: the length is 116mm, the width is 26mm, and the height is 26mm; the width that first bar led to the groove and the groove is led to the second bar is 3mm, the length that first bar led to the groove is 120mm, the length that the groove was led to the second bar is 20mm.
In the above scheme, the length, width and height of the mouse fixing seat are all 24mm, the minimum diameter of the conical through hole is 5mm, and the maximum diameter is 23mm.
In the scheme, the width and the height of the tail support are respectively 9.5mm and 10mm, the length of the tail support is one of 50mm/40mm/30mm, the width and the depth of the tail fixing groove are respectively 3mm and 2mm, and the length of the tail fixing groove (31) is the same as that of the tail support.
In the above scheme, the base is close to one side bottom of tail support mounting groove and is equipped with the supporting leg subassembly, the supporting leg subassembly is equipped with two sets ofly, sets up both ends about the bottom of base respectively, one side bottom that the tail support mounting groove was kept away from to the base is equipped with the lip block.
In the above scheme, the supporting leg subassembly includes supporting screw, supporting screw's lower extreme is equipped with the callus on the sole, the base bottom is equipped with the supporting leg mounting groove, the opening part of supporting leg mounting groove is fixed with the nut with the supporting screw adaptation, the upper end of supporting screw runs through the nut and stretches into in the supporting leg mounting groove.
The invention has the beneficial effects that:
1. compared with the conventional portable mouse tail vein injection fixing instrument, the tail vein injection fixing instrument is more advanced and humanized, and the success rate of mouse tail vein injection of researchers, particularly zero-experience researchers, is improved; the invention is equivalent to other portable mouse tail vein injection fixing instruments in cost, has stronger market competitiveness and obtains better market benefit.
2. According to the invention, the base and the fixer body are arranged to be detachable structures, meanwhile, the fixer body is arranged to be a cuboid structure, and three side surfaces of the fixer body, which are not provided with the first strip-shaped groove, can be combined with the base, so that three tail veins of a mouse can be respectively and fully exposed; more convenient for injecting the tail vein of the mouse.
3. The base of the invention can be embedded with tail supports with different lengths, can meet the intravenous injection requirements of mice with different tail lengths, and is more convenient to use.
4. According to the invention, through the arrangement of the supporting leg assembly and the supporting cushion block, the height of one side, close to an operator, of the base can be adjusted, so that the base can adapt to the operation heights of different operators, and the use is more convenient.
Description of the drawings:
FIG. 1 is a schematic view of the structure of the present invention;
FIG. 2 is a schematic view of a detailed structure of a base of the present invention;
FIG. 3 is a schematic view of the detailed structure of the anchor body according to the present invention;
FIG. 4 is a schematic view of a specific structure of the mouse holder according to the present invention;
FIG. 5 is a schematic structural view of a support leg assembly of the present invention;
wherein the reference numerals are: 1-base, 2-fixer body, 3-tail support, 4-mouse fixing seat, 5-supporting leg component, 11-groove, 12-tail support mounting groove, 13-supporting cushion block, 14-supporting leg mounting groove, 15-nut, 21-mouse inlet and outlet, 22-first strip-shaped through groove, 23-second strip-shaped through groove, 31-mouse tail fixing groove, 41-conical through hole, 42-fixing screw rod, 43-fixing nut, 51-supporting screw rod and 52-foot pad.
Detailed Description
The technical solutions of the present invention will be described clearly and completely with reference to the following embodiments, and it should be understood that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be obtained by a person skilled in the art without inventive effort based on the embodiments of the present invention, are within the scope of the present invention.
Example 1
A mouse fixer for mouse tail vein injection comprises a base 1, wherein a groove 11 is formed in the base 1, a fixer body 2 is arranged on the groove 11, a tail support installation groove 12 is formed between the groove 11 and the edge of the base 1, a tail support 3 is installed in the tail support installation groove 12, a tail support fixing groove 31 is formed in the upper surface of the tail support 3, a mouse inlet 21 is formed in one side, away from the tail support installation groove 12, of the fixer body 2, a first strip-shaped through groove 22 is formed in the top surface of the fixer body 2 along the length direction of the fixer body 2, a second strip-shaped through groove 23 is formed in the side wall, close to the tail support installation groove 12, of the fixer body 2 along the height direction of the fixer body 2, the first strip-shaped through groove 22 is communicated with the second strip-shaped through groove 23, a mouse fixing seat 4 is arranged in the fixer body 2, a conical through hole 41 with a horizontal axis is formed in the middle of the mouse fixing seat 4, the aperture of the conical through hole 41 is gradually increased along the direction close to the tail support installation groove 12, a fixing screw 42 is arranged at the top of the mouse fixing seat 4, the upper end of the fixing screw 42 penetrates through the first strip-shaped through groove 22, and the fixing screw rod 42 can be matched with the screw along the first strip-shaped through groove 42 in the fixing screw rod along the length direction;
in this embodiment, through the setting of base 1, fixer body 2, tail support 3, mouse fixing base 4, utilize mouse fixing base 4 to fix the head of mouse, put into fixer body 1 with mouse fixing base 4 again together with the mouse, screw up fixing nut 43, fix the mouse, fix the tail of mouse in tail support 3 again, can accomplish the tail vein injection of mouse.
Example 2
On the basis of embodiment 1, the length, width and height of the base 1 are respectively 150mm, 120mm and 8mm, the length, width and depth of the groove 11 are respectively 121mm, 31mm and 5mm, the length, width and depth of the tail stock mounting groove 12 are respectively 10mm, 10mm and 5mm, and the outer diameter of the fixer body 2: the length is 120mm, the width is 30mm, and the height is 30mm; inner diameter: length 116mm, width 26mm, height 26mm; the widths of the first strip-shaped through groove 22 and the second strip-shaped through groove 23 are both 3mm, the length of the first strip-shaped through groove 22 is 120mm, and the length of the second strip-shaped through groove 23 is 20mm;
in this embodiment, the base 1 and the holder body 2 are detachably configured, and the holder body 2 is configured as a rectangular parallelepiped, so that three sides of the holder body 2, which are not provided with the first strip-shaped groove 22, can be combined with the base 1, so that three tail veins of the mouse can be fully exposed; more convenient for injecting the tail vein of the mouse.
Example 3
On the basis of the embodiment 1 or 2, the length, the width and the height of the mouse fixing seat 4 are all 24mm, the minimum diameter of the conical through hole 41 is 5mm, and the maximum diameter is 23mm;
in this embodiment, the head of the mouse is fixed by the tapered through hole 41, and at the same time, the tapered through hole 41 opens the mouse fixing seat 4, so that the mouse can breathe conveniently.
Example 4
On the basis of the above embodiment, the width and the height of the tail stock 3 are respectively 9.5mm and 10mm, the length of the tail stock 3 is one of 50mm/40mm/30mm, the width and the depth of the tail fixing groove 31 are respectively 3mm and 2mm, and the length of the tail fixing groove 31 is the same as that of the tail stock;
on the basis of this embodiment, the base 1 can inlay the tail of different length and hold in the palm 3, can adapt to the intravenous route demand of the mouse of different tail lengths, uses more convenient.
Example 5
On the basis of the above embodiment, the bottom of one side of the base 1 close to the tail stock mounting groove 12 is provided with the supporting leg assemblies 5, the supporting leg assemblies 5 are provided with two groups and are respectively arranged at the left end and the right end of the bottom of the base 1, and the bottom of one side of the base 1 far away from the tail stock mounting groove 12 is provided with the supporting cushion block 13.
Example 6
On the basis of the above embodiment, the supporting leg assembly 5 includes a supporting screw 51, a foot pad 52 is arranged at the lower end of the supporting screw 51, a supporting leg installation groove 14 is arranged at the bottom of the base 1, a nut 15 adapted to the supporting screw 51 is fixed at an opening of the supporting leg installation groove 14, and the upper end of the supporting screw 51 penetrates through the nut 15 and extends into the supporting leg installation groove 14;
in the embodiment, the height of the base 1 close to one side of an operator can be adjusted through the arrangement of the supporting screw 51, the supporting leg mounting groove 14, the nut 15 and the supporting cushion block 13, so that the operation heights of different operators can be adapted, and the use is more convenient.
The foregoing is illustrative of the preferred embodiments of this invention, and it is to be understood that the invention is not limited to the precise form disclosed herein and that various other combinations, modifications, and environments may be resorted to, falling within the scope of the concept as disclosed herein, either as described above or as apparent to those skilled in the relevant art. And that modifications and variations may be effected by those skilled in the art without departing from the spirit and scope of the invention as defined by the appended claims.
Claims (6)
1. A mouse fixer for mouse tail vein injection comprises a base (1) and is characterized in that: the mouse fixing device is characterized in that a groove (11) is formed in the base (1), a fixer body (2) is arranged on the groove (11), a tail support mounting groove (12) is formed between the groove (11) and the edge of the base (1), a tail support (3) is installed in the tail support mounting groove (12), a mouse tail fixing groove (31) is formed in the upper surface of the tail support (3), a mouse inlet and outlet (21) is formed in one side, away from the tail support mounting groove (12), of the fixer body (2), a first strip-shaped through groove (22) is formed in the top surface of the fixer body (2) along the length direction of the fixer body (2), a second strip-shaped through groove (23) is formed in the side wall, close to the tail support mounting groove (12), of the fixer body (2) and communicated with the second strip-shaped through groove (23) along the height direction of the fixer body (2), a mouse fixing seat (4) is arranged in the fixer body (2), a conical through hole (41) with a horizontal axis is formed in the middle of the mouse fixing seat (4), a hole (41) is formed in the tail support mounting groove (12) and a screw rod (42) penetrates through the fixing seat (22) and extends out of the fixing screw rod (42), the fixing screw rod (42) can freely move in the first strip-shaped through groove (22) along the length direction of the first strip-shaped through groove (22), and a fixing nut (43) matched with the fixing screw rod (42) is arranged on the fixing screw rod.
2. The mouse fixer for mouse tail vein injection according to claim 1, characterized in that: the length, width, height of base (1) are 150mm, 120mm, 8mm respectively, and the length, width, the degree of depth of recess (11) are 121mm, 31mm, 5mm respectively, and the length, width, the degree of depth of tail support mounting groove (12) are 10mm, 5mm respectively, the external diameter of fixer body (2): the length is 120mm, the width is 30mm, and the height is 30mm; inner diameter: length 116mm, width 26mm, height 26mm; the width of the first strip-shaped through groove (22) and the width of the second strip-shaped through groove (23) are both 3mm, the length of the first strip-shaped through groove (22) is 120mm, and the length of the second strip-shaped through groove (23) is 20mm.
3. The mouse fixer for mouse tail vein injection according to claim 2, characterized in that: the length, the width and the height of the mouse fixing seat (4) are all 24mm, the minimum diameter of the conical through hole (41) is 5mm, and the maximum diameter is 23mm.
4. The mouse fixer for mouse tail vein injection according to claim 2, characterized in that: the width and the height of the tail support (3) are respectively 9.5mm and 10mm, the length of the tail support (3) is one of 50mm/40mm/30mm, the width and the depth of the tail fixing groove (31) are respectively 3mm and 2mm, and the length of the tail fixing groove (31) is the same as that of the tail support.
5. The mouse fixer for mouse tail vein injection according to claim 1, characterized in that: the base (1) is close to one side bottom of tail support mounting groove (12) and is equipped with supporting leg subassembly (5), supporting leg subassembly (5) are equipped with two sets ofly, set up both ends about the bottom of base (1) respectively, one side bottom that tail support mounting groove (12) was kept away from in base (1) is equipped with supporting pad (13).
6. The mouse fixer for mouse tail vein injection according to claim 5, characterized in that: supporting leg subassembly (5) are including supporting screw (51), the lower extreme of supporting screw (51) is equipped with callus on the sole (52), base (1) bottom is equipped with supporting leg mounting groove (14), the opening part of supporting leg mounting groove (14) is fixed with nut (15) with supporting screw (51) adaptation, the upper end of supporting screw (51) is run through in nut (15) stretch into supporting leg mounting groove (14).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211294951.5A CN115737185A (en) | 2022-10-21 | 2022-10-21 | Mouse fixer for mouse tail vein injection |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211294951.5A CN115737185A (en) | 2022-10-21 | 2022-10-21 | Mouse fixer for mouse tail vein injection |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN115737185A true CN115737185A (en) | 2023-03-07 |
Family
ID=85352827
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202211294951.5A Pending CN115737185A (en) | 2022-10-21 | 2022-10-21 | Mouse fixer for mouse tail vein injection |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN115737185A (en) |
-
2022
- 2022-10-21 CN CN202211294951.5A patent/CN115737185A/en active Pending
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