CN115701800A - In-vitro blood pump system for on-line instant obtaining blood parameters - Google Patents
In-vitro blood pump system for on-line instant obtaining blood parameters Download PDFInfo
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- CN115701800A CN115701800A CN202211081002.9A CN202211081002A CN115701800A CN 115701800 A CN115701800 A CN 115701800A CN 202211081002 A CN202211081002 A CN 202211081002A CN 115701800 A CN115701800 A CN 115701800A
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Abstract
An extracorporeal blood pump system for on-line and immediate acquisition of blood parameters is disclosed, wherein a control host is used for controlling the motor operation of an extracorporeal magnetic suspension blood pump, an extracorporeal circulation pipeline assembly is connected with a pump head and a subject of the extracorporeal magnetic suspension blood pump, and the extracorporeal circulation pipeline assembly is provided with a radial cavity which radially penetrates through a pipe wall at least in a pipeline setting section where a pressure sensor is arranged. The pressure sensor is connected with the control host and comprises a shell formed outside the pipeline arrangement section and a sensing part arranged in the shell, wherein the sensing part comprises a radial part at least partially embedded in the radial cavity, and a gap is formed between the radial part and the inner wall of the radial cavity. A passage communicating with the gap is formed in the housing, and the blood gas detecting element is provided in the passage. A blood recovery module is disposed in the housing and has a chamber in communication with the channel.
Description
Technical Field
The present application relates to an extracorporeal blood pump system for on-line immediate acquisition of blood parameters.
Background
When the extracorporeal centrifugal magnetic suspension blood pump is used for ventricular assist of a testee, blood pressure, blood gas parameters and the like are key parameters. The stabilization of blood pressure and blood gas parameters is crucial for the subject. That is, it is not clinically desirable for some emergency situations to cause the above-mentioned blood parameters to change.
However, in practice, undesirable conditions that result in changes in blood pressure and blood gas parameters are difficult to avoid. In particular, an external centrifugal magnetic suspension blood pump is connected to a human body through a cannula, and a large number of bendable hoses exist outside the body. The movement of the subject or the surrounding personnel can cause the external hose to bend, so that the blood circulation in vitro is blocked, and the blood pressure and the blood gas parameters are changed. In addition, extracorporeal circulation cannulas may experience tube diameter changes when subjected to high or varying blood pressures. The tube diameter changes, which leads to unstable blood pressure and blood-gas parameters.
Therefore, it is desirable to have a means for instantly or rapidly acquiring blood pressure and blood gas parameters in order to assist medical staff to timely adjust the operation of the device in a ventricular assist scene in which an extracorporeal centrifugal magnetic levitation blood pump is applied.
Disclosure of Invention
In view of the above, embodiments of the present invention provide an extracorporeal blood pump system for obtaining blood parameters on-line and on-line, which at least partially solves one of the above problems.
In order to achieve the purpose, the invention provides the following technical scheme:
an extracorporeal blood pump system for on-line immediate acquisition of blood parameters comprises: the system comprises an extracorporeal magnetic suspension blood pump, a control host, an extracorporeal circulation pipeline assembly, a pressure sensor, a blood gas detection element and a blood recovery module. The extracorporeal magnetic levitation blood pump comprises a motor and a pump head detachably connected with the motor. The pump head includes a pump housing having a blood inlet and a blood outlet, an impeller suspendably disposed within the pump housing, the impeller being rotatable by a motor to pump blood from the blood inlet to the blood outlet. The control host is connected with the motor and used for controlling the operation of the motor. The extracorporeal circulation pipeline assembly comprises a first pipe with one end connected with the blood inlet and a second pipe with one end connected with the blood outlet, and the other ends of the first pipe and the second pipe are used for being connected to a subject. The extracorporeal circuit line arrangement has a radial cavity which extends radially through the tube wall, at least in a line placement section in which the pressure sensor is arranged. The pressure sensor is connected with the control host and comprises a shell formed outside the pipeline setting section and a sensing part arranged in the shell. The sensing portion includes a radial portion at least partially embedded in the radial cavity, the radial portion forming a gap with an inner wall of the radial cavity. A passage communicating with the gap is formed in the housing, and the blood gas detecting element is provided in the passage. A blood recovery module is disposed in the housing and has a chamber in communication with the channel.
Through the integrated setting of pressure sensor's sensing portion and blood gas detection component in the sensor housing, realize detecting simultaneously to the pressure of blood and blood gas parameter to for the control host computer provides the control decision-making, and make things convenient for medical personnel to learn the patient condition immediately, and then can receive the regulation or take other necessary measures to this system in view of the above.
Drawings
FIG. 1 is a block diagram of an extracorporeal blood pump system in accordance with an embodiment of the present invention;
FIG. 2 is a schematic view of the assembly of the pressure sensor and the extracorporeal circuit assembly of the first embodiment;
FIG. 3 is a schematic view of the second embodiment of FIG. 2;
FIG. 4 is a schematic view of the assembly of a pressure sensor and an extracorporeal circuit assembly according to a second embodiment;
FIG. 5 is a schematic diagram of a pressure sensor and extracorporeal circuit assembly in accordance with a third embodiment;
FIG. 6 is a schematic view of the assembly of a pressure sensor and an extracorporeal circuit assembly according to a fourth embodiment;
fig. 7 is a schematic view of the assembly of a pressure sensor and an extracorporeal circuit assembly according to a fifth embodiment.
Detailed Description
As shown in fig. 1, an extracorporeal blood pump system provided in an embodiment of the present invention includes: the extracorporeal magnetic suspension blood pump 100, the control host 200, the extracorporeal circulation pipeline assembly 300 and the pressure sensor 400.
The extracorporeal magnetically levitated blood pump 100 includes a magnetically levitated motor 101 and a pump head 102 removably engaged with the magnetically levitated motor 101. The pump head 102 includes a pump housing, an impeller housed within the pump housing. The impeller may be suspended within the pump housing and may be driven to rotate by the motor 101 to pump blood from the blood inlet to the blood outlet of the pump housing. The specific structure of the pump head 102 and the motor 101, and the principle of driving the impeller by the motor 101, can be referred to the known embodiments provided under the publication numbers CN114748788a or CN114668967 a. The suspension of the impeller within the pump housing can be achieved by means of known embodiments provided under the publication numbers CN111561519B or CN 112546425B. The operative engagement between the pump head 102 and the motor 101 may employ a known embodiment provided under the publication number CN209187707U, CN209204247U, CN 209204246U. The control main unit 200 is connected to the motor 101 for controlling the operation of the motor 101. The controlling host 200 may adopt a known embodiment as provided in the publication No. CN209713797U, which is not described herein.
The extracorporeal circuit assembly 300 includes: a first tube 301 having one end connected to the blood inlet, a second tube 302 having one end connected to the blood outlet, the other end of the first tube 301 and the other end of the second tube 302 being for connection to a subject. The pressure sensor 400 is provided on the extracorporeal circuit assembly 300 (on the first tube 301 or the second tube 302) and is connected to the control main unit 200, for providing the detected blood pressure to the control main unit 200. When it is judged that the blood pressure exceeds the threshold range based on the blood pressure provided by the pressure sensor 400, the control host 200 controls to perform corresponding operations, including controlling the alarm module to operate and/or controlling the motor 101 to adjust the rotation speed.
The threshold range is set by the user on the control host 200 in advance, and the set threshold range is different according to the applicable scene and/or different subjects, such as adults or children. For example, an adult subject may require a greater amount of ventricular assist flow, a pediatric subject may require a lesser amount of ventricular assist flow, and the flow thresholds for the two different subjects may differ.
Blood pressure exceeding the threshold range includes being below a lower threshold and being above an upper threshold. The alarm unit operation comprises sound alarm, light flashing alarm, combined alarm of the sound alarm and the light flashing alarm and the like, and is used for reminding a guardian to take corresponding measures in time. Controlling the motor 101 to adjust the speed includes increasing and decreasing the speed. When the blood pressure is below the lower threshold, the motor 101 is controlled to ramp up. When the blood pressure is higher than the upper threshold, the motor 101 is controlled to be decelerated.
The parameters of the blood in the extracorporeal circulation process are detected by arranging the pressure sensor 400, and the detected parameters are compared with a set threshold range to judge whether the blood is in a normal range in the extracorporeal circulation process. When the blood pressure is judged to be abnormal, the blood pressure is restored to a normal range by executing corresponding operation, and the ventricular assist of the testee is ensured to be always performed normally.
As shown in fig. 2 and 3, in the first embodiment, the pressure sensor 400 has a horizontal portion 401 and a radial portion 402, and the extracorporeal circuit assembly 300 has a radial cavity 301 extending radially through the wall of the tube. The horizontal portion 401 abuts the wall of the extracorporeal circuit assembly 300 and the radial portion 402 is at least partially disposed within the radial cavity 301 and does not extend beyond the radial cavity 301 such that the pressure sensor 400 is in communication with blood within the extracorporeal circuit assembly 300.
The extracorporeal circuit module 300 is externally provided with a housing 407, and the pressure sensor 400 is housed therein. A female connector 408 for connection to the pressure sensor 400 is provided in the wall of the housing 407 for connection to a wire. Radial portion 402 of pressure sensor 400 is disposed in radial cavity 301 and proximate to the inner surface of extracorporeal circulation circuit assembly 300, including radial portion 402 being entirely within radial cavity 301 and radial portion 402 being flush with the inner surface of extracorporeal circulation circuit assembly 300. This at least reduces the eddies and obstructions to the blood flow that may be caused by the placement of pressure sensor 400 to the blood flow, and avoid the formation of thrombus.
In order to reduce the unstable detection of blood parameters (including blood pressure and blood gas parameters) caused by the change of the tube diameter of the extracorporeal circulation circuit assembly 300, the tube diameter increasing rate of the first tube 301 and the second tube 302 contained in the extracorporeal circulation circuit assembly 300 when the first tube 301 and the second tube 302 bear the maximum pressure head of the extracorporeal magnetic suspension blood pump 100 is limited through the selection of materials and the wall thickness of the tubes. The extracorporeal circulation line assembly 300 may be made of any one of PVC, PE, or TPU, with a wall thickness of between 1.5mm and 3.5mm, and further between 2mm and 3 mm. In this way, at least at the maximum pressure head of the conduit arrangement section 306 where the pressure sensor 400 is arranged, the increasing rate of the conduit diameter of the extracorporeal circulation conduit assembly 300 is not more than 5%, for example less than 3%, and further less than 1%, even at the maximum pressure head of the extracorporeal blood pump 100, the conduit diameter does not change.
Wherein, the maximum pressure head of the extracorporeal magnetic suspension blood pump 100 corresponds to the maximum rotation speed of the motor 101, for example 5000rpm. In practice, the maximum rotation speed of the motor 101 is different under different situations, and therefore is not limited herein. The pipeline setting section 306 has a small-amplitude pipe diameter increasing rate when meeting the requirement of bearing the maximum pressure head of the external magnetic suspension blood pump 100, and accordingly, the maximum pipe diameter reducing rate of the external magnetic suspension blood pump 100 can be supported not to be too large, for example, not more than 3%, further less than 1%, or even unchanged, in the process of gradually reducing from the maximum pressure head.
It is noted that any numerical value in this disclosure includes all values from the lower value to the upper value that are incremented by one unit, and that there may be an interval of at least two units between any lower value and any higher value.
For example, the tube diameter increase is not more than 5%, such as less than 3%, and further less than 1%, for the purpose of illustrating values such as less than 4%, 2%, 0% not expressly recited above.
As noted above, the exemplary range of 2% intervals does not preclude increases in intervals in appropriate units, such as 1%, 0.5%, etc. numerical units. These are only examples of what is intended to be explicitly recited, and all possible combinations of numerical values between the lowest value and the highest value that are explicitly recited in the specification in a similar manner are to be considered.
Unless otherwise indicated, all ranges are inclusive of the endpoints and all numbers between the endpoints. The use of "about" or "approximately" with a range applies to both endpoints of the range. Thus, "about 20 to about 30" is intended to cover "about 20 to about 30", including at least the endpoints specified.
Other definitions of numerical ranges appearing herein may be found in reference to the above description and are not repeated here.
To facilitate clinical deployment and line management of the tubing, the extracorporeal circuit assembly 300 is generally flexible and bendable, preferably in areas of the tubing other than the section of the tubing in which the pressure sensor 400 is disposed. This also means that the hardness of the tubing set section 306 is greater than the hardness of the other tubing sections of the external circulation tubing set 300, and that the length of the tubing set section 306 is at least greater than the length of the horizontal portion 401 of the pressure sensor 400. Because pressure sensor 400 is less in actual length, the benefit of setting like this is that the flexibility of whole pipeline is not reduced obviously, makes things convenient for clinical wiring and reason line, can provide sufficient rigidity for pressure sensor 400's setting again, prevents to set up pipeline section 306 of pressure sensor 400 and lead to pressure sensor 400 to appear unexpected drop, leak blood etc. owing to take place to bend or buckle.
As shown in fig. 3, in order to achieve the stiffness setting of the different sections of the conduit, and in particular the conduit providing section 306 having a greater radial stiffness without a significant loss of flexibility or bendability, an alternative embodiment is that the conduit providing section 306 comprises a substrate tube made of a flexible substrate and a reinforcing structure 302 circumferentially surrounding the substrate tube body for limiting further radial expansion of the substrate tube body. The tubing set section 306 may incorporate a braided construction based on the materials of construction described above. In this way, the conduit setting section 306 has a better resistance to change in the radial direction without losing its bending properties.
It should be noted that the base material pipe made of the flexible base material is combined with the woven structure, which is only one practical structure. In other possible solutions, the braided construction may be replaced by other means of construction. For example, a plurality of stretch resistant rings are circumferentially spaced apart and disposed outside the flexible substrate tube body to provide an inward circumferential force to the flexible substrate tube body.
The braided structure and stretch resistant rings form a reinforcing structure that circumferentially surrounds the flexible substrate tube to limit further expansion of the substrate tube in the radial direction. In this way, the flexible substrate tube body provides clinically desirable flexibility, and the reinforcing structure provides the flexible substrate tube body with a stiffness that improves radial resistance to expansion. In addition, the flexibility of the flexible base material pipe body is not affected by the stretch-resistant rings arranged at intervals or in a weaving structure.
By virtue of the design of the reinforcing structure 302, the pipeline section 306 cannot be bent, so that the risk of failure of the pressure sensor 400 due to bending is reduced, and the risk of loosening of the pressure sensor 400 due to bending and the risk of blood leakage are reduced.
As shown in fig. 4, another alternative embodiment to achieve a large stiffness of the conduit section 306 is that the pressure sensor 400 comprises a rigid fixture 403 and a sensing portion 404, a radial portion of the rigid fixture 403 is disposed in the radial cavity 301, and a horizontal portion abuts against the outer wall of the extracorporeal circuit conduit assembly 300. The hard mount 403 has a radial cavity 405 extending radially therethrough, the radial portion 402 of the sensing portion 404 is at least partially disposed in the radial cavity 405, and the horizontal portion 401 abuts against an outer wall of the horizontal portion of the hard mount 403. Pressure sensor 400 is provided by a rigid mount 403 that protects the sensor chip from being crushed by bending of tubing section 306.
The extracorporeal circulation pipe assembly 300 is externally provided with a hard outer shell 406 and an end cover 409, one end of the hard outer shell 406 is abutted against one end of the horizontal part 401 of the hard fixing member 403, and the end cover 409 is positioned outside the other end of the hard fixing member 403 and is connected with the other end of the hard outer shell 406. A hole 411 for passing the lead 410 is formed in the hard case 407 or the end cap 409, and the lead 410 is connected to the sensor portion 404.
The rigid outer housing 406 and end cap 409 are cylinders with a central bore through which the extracorporeal circuit assembly 300 is mounted from one direction. The hard fixture 403 is tightly fitted with the extracorporeal circulation line assembly 300 and is bonded with glue, which is a work piece. Pressure sensor 400 is mounted in a radial cavity 405 of a rigid fixture 403, with a clearance fit, and secured with glue. The horizontal portion 401 of the hard fixing member 403 and the step formed by the extracorporeal circulation circuit assembly 300 are used to limit the hard housing 406, which facilitates subsequent glue fixation. The wires are connected directly to pressure sensor 400 and the wires are routed through holes in end cap 409 to connect pressure sensor 400 to external equipment.
As shown in fig. 5, in the third embodiment, the radial cavity 301 is a stepped cavity including an outer cavity 3011 and an inner cavity 3012 in the radial direction, and the diameter of the inner cavity 3012 is smaller than that of the outer cavity 3011. The horizontal portion 401 of the pressure sensor 400 is disposed in the outer cavity 3011 and the radial portion 402 is disposed in the inner cavity 3012. As in the first embodiment shown in fig. 2, the extracorporeal circulation circuit assembly 300 is externally provided with a housing 407 in which the pressure sensor 400 is housed. A female connector 408 for connection to the pressure sensor 400 is provided in the wall of the housing 407 for connection to a wire. The large bore (outside cavity 3011) of the stepped bore is clearance fit with the horizontal portion 401 of the pressure sensor 400 and the small bore (inside cavity 3012) is the same size as the radial portion 402 of the pressure sensor 400.
In the fourth embodiment, as shown in fig. 6, the extracorporeal circulation circuit assembly 300 has a radial cavity 303 penetrating the wall of the tube in the radial direction, the inner and outer surfaces of the tube wall are provided with elastic covering films 304, 305 which seal the radial cavity 303 and are deformable, a fluid medium such as liquid capable of conducting blood pressure is sealed in the radial cavity 303, and the pressure sensor 400 is arranged on the outer wall of the extracorporeal circulation circuit assembly 300 and corresponds to the radial cavity 303. The blood pressure in the extracorporeal circuit assembly 300 can be detected by the inner covering membrane 304 pressing the fluid medium enclosed in the radial cavity 303, which further transmits the pressure to the outer covering membrane 305, so that the pressure sensor 400 can receive the pressure.
As shown in fig. 7, in the fifth embodiment, the reinforcing structure 302 includes a first coil 307 formed in the pipe wall of the flexible substrate pipe body, the first coil 307 has two coupling points, and the two coupling points are connected with the radial portion 402 of the pressure sensor 400, so that the pressure sensor 400 and the first coil 307 form a closed loop. The system further comprises a second coil 308 coupled to the first coil 307, an excitation signal source 311 coupled to the pressure sensor 400 to trigger the pressure sensor 400 to resonate.
In this embodiment, the pressure sensor 400 is a wireless pressure sensor and the closed loop with the first coil 307 is an LC resonant circuit. The principle of detecting the blood pressure by cooperating with the second coil 308 and the excitation signal source 311 can be seen in the known embodiment of US10307067B1, which is not described herein again.
In this way, the first coil 307 forming the structure of the wireless pressure sensor 400 itself is the reinforcing structure 302 to increase the radial stiffness of the pipeline section 306, or the coil 307 necessary for constructing the structure of the wireless pressure sensor 400 itself is used as the reinforcing structure 302 to increase the radial stiffness of the pipeline section 306, so that a synergistic effect is achieved, and the structure is simplified. The first coil 307 is helically or S-shaped in a serpentine shape such that the first coil 307 may be circumferentially wound to increase radial stiffness without loss of flexibility.
The second coil 308, acting as an antenna, may be disposed in the pipe section 306. In particular, the component containing the second coil 308 may be used as an additional component in conjunction with the wireless pressure sensor 400 to receive, process, and display the blood pressure signal. Of course, in other embodiments, the second coil 308 may also be formed within the wall of the flexible substrate tube to form part of the reinforcing structure 302. In this way, the first coil 307 and the second coil 308 configured as the wireless pressure sensor 400 act as a reinforcing structure that enhances the radial stiffness of the pipeline section 306, further enhancing the radial stiffness of the pipeline section 306 without adding other physical structures.
Referring to fig. 2, a housing 407 is disposed outside the pipeline installation section 306, the driving signal source 311 is disposed inside the housing 407, and a conductive wire is disposed through a wall of the housing 407 and connected to the second coil 308 for transmitting signals to an external device.
As shown in fig. 7, to realize the detection of the blood gas parameter, the extracorporeal blood pump system further includes a blood gas detecting element 500 (e.g., a micro-fluidic chip) disposed in the housing 407 of the pressure sensor 400 and a blood recovering module 600 configured to recover waste blood for detecting the blood gas parameter. The blood gas parameters that can be measured by the blood gas detecting element 500 include parameters such as the blood oxygen saturation SO, the oxygen partial pressure PO2, the total carbon dioxide TCO2, and the hemoglobin Hb. The scheme for communicating the blood gas detection element 500 with blood is as follows: a gap 309 through which blood flows is formed between the radial portion 402 of the pressure sensor 400 and the inner wall of the radial chamber 301, a passage 310 communicating with the gap 309 is formed in the sensor housing 407, and the blood gas detecting element 500 is provided in the passage 310. The blood recovery module 600 has a chamber communicating with the channel 310, and blood (waste blood) which enters the channel 310 through the gap 309 and is detected by the blood gas detection element 500 to be collected into the blood recovery module 600.
By integrating the sensing part 404 of the pressure sensor 400 with the blood gas detection element 500 in the sensor housing 407, the simultaneous detection of the pressure of blood and the blood gas parameters is realized, so that a control decision is provided for the control host 200, medical staff can learn about the condition of a patient conveniently, and the system can be adjusted accordingly or other necessary measures can be taken. For example, if the system is operating in an ECMO scenario, the oxygen flow to the oxygenator and the warm water flow affecting the oxygenation efficiency may be appropriately changed (increased or decreased). Alternatively, a suitable agent, such as an anticoagulant, is introduced.
The sensor housing 407 further has a PCB312 connected to the blood gas detecting element 500, and the PCB312 is connected to the control host 200, and is used for performing processing such as noise reduction and amplification on data detected by the blood gas detecting element 500, and then providing the processed data to the control host 200 for judgment, so as to reduce the operation burden of the control host 200.
The control host 200 determines that the blood gas parameter exceeds the threshold range based on the blood gas parameter detected by the blood gas detecting element 500 provided by the PCB312, and controls to perform similar operations as above, including controlling the alarm module to operate and/or controlling the motor 101 to adjust the rotation speed. It is noted that the control host 200 controls the execution of the operation, which may be based on at least one of blood pressure and blood gas parameters.
As shown in fig. 7, the gap 309 communicates with the channel 310 in the following manner: the horizontal portion 401 of the sensor 400 has a reduced thickness of its lower surface on the same side as the gap 309, and this reduced thickness portion of the lower surface is spaced from the outer wall of the pipe-setting section for insertion of the wall defining the channel 310 into the space.
The sensor housing 407 is provided with a power supply unit 312, such as a battery, connected to the excitation signal source 311, and the power supply unit 312 is detachably connected to the sensor housing 407. Further, the blood collection module 600 is also removably attached to the sensor housing 407 housing. The blood collection module 600 is fixed to the power supply unit 312 to form an integral unit. The removable connection of both to the sensor housing 407 may be by any suitable conventional means, such as an in-line connection.
Thus, after a certain period of time or a case of ventricular assist of a patient, the blood recovery module 600 and the power supply unit 312 can be removed as a unit and replaced with a new module to ensure that the system has sufficient power for the next use and to avoid blood contact between different patients.
It is to be understood that the above description is intended to be illustrative, and not restrictive. Many embodiments and many applications other than the examples provided would be apparent to those of skill in the art upon reading the above description. The scope of the present teachings should, therefore, be determined not with reference to the above description, but should instead be determined with reference to the appended claims, along with the full scope of equivalents to which such claims are entitled.
The disclosures of all articles and references, including patent applications and publications, are hereby incorporated by reference for all purposes. The omission in the foregoing claims of any aspect of subject matter that is disclosed herein is not intended to forego such subject matter, nor should the inventors be construed as having contemplated such subject matter as being part of the disclosed subject matter.
Claims (10)
1. An extracorporeal blood pump system for on-line real-time acquisition of blood parameters, comprising: the system comprises an extracorporeal magnetic suspension blood pump, a control host, an extracorporeal circulation pipeline assembly, a pressure sensor, a blood gas detection element and a blood recovery module;
the in vitro magnetic suspension blood pump comprises: a motor, a pump head removably engaged with the motor; the pump head includes: a pump housing having a blood inlet and a blood outlet, an impeller suspendably disposed within the pump housing; the impeller is rotatably driven by the motor to pump blood from the blood inlet to the blood outlet;
the control host is connected with the motor and used for controlling the motor to operate;
the extracorporeal circulation circuit assembly includes: a first tube having one end connected to the blood inlet and a second tube having one end connected to the blood outlet; the other end of the first tube and the other end of the second tube are for connection to a subject; the extracorporeal circulation pipeline assembly is provided with a radial cavity penetrating through a pipe wall in the radial direction at least at a pipeline setting section where the pressure sensor is arranged;
the pressure sensor with the control host computer is connected, includes: the shell is formed outside the pipeline arrangement section, and the sensing part is arranged in the shell; the sensing part comprises a radial part at least partially embedded in the radial cavity, and a gap for blood to flow is formed between the radial part and the inner wall of the radial cavity;
a channel communicated with the gap is formed in the shell, and the blood gas detection element is arranged in the channel;
the blood recovery module is disposed in the housing and has a chamber in communication with the passageway.
2. The extracorporeal blood pump system of claim 1, the sensing portion further comprising a horizontal portion abutting an outer wall of the tubing set section adjacent the radial portion, the radial portion not exceeding the radial cavity such that the pressure sensor is in communication with blood within the extracorporeal circulation tubing set.
3. The extracorporeal blood pump system of claim 2 wherein the horizontal portion has a reduced thickness of a lower surface on the same side as the gap, the reduced thickness portion being spaced from an outer wall of the tubing set section for insertion of a wall defining the channel into the gap.
4. The extracorporeal blood pump system of claim 1, the conduit-setting section comprising: a substrate tube body made of a flexible substrate, a reinforcing structure circumferentially surrounding the substrate tube body for limiting further expansion of the substrate tube body in a radial direction.
5. The extracorporeal blood pump system of claim 4, the reinforcing structure comprising: a first coil formed within a tube wall of the flexible substrate tube; the first coil is connected with the radial part so that the pressure sensor and the first coil form a closed loop;
the system further comprises: a second coil coupled with the first coil, an excitation signal source coupled with the pressure sensor to trigger the pressure sensor to resonate.
6. The extracorporeal blood pump system of claim 5, wherein the second coil is formed within a wall of the flexible substrate tube, and the reinforcing structure comprises the second coil.
7. The extracorporeal blood pump system of claim 5, wherein the excitation signal source is disposed within the housing, and a wire is threaded through a wall of the housing and connected to the second coil.
8. The extracorporeal blood pump system of claim 5, wherein the housing has a power supply unit connected to the excitation signal source, the power supply unit being removably connected to the housing.
9. The extracorporeal blood pump system of claim 8, wherein the blood recovery module is removably coupled to the housing.
10. The extracorporeal blood pump system of claim 9, wherein the blood recovery module is fixedly disposed with the power unit to form a unitary piece.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211081002.9A CN115701800A (en) | 2022-09-05 | 2022-09-05 | In-vitro blood pump system for on-line instant obtaining blood parameters |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211081002.9A CN115701800A (en) | 2022-09-05 | 2022-09-05 | In-vitro blood pump system for on-line instant obtaining blood parameters |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN115701800A true CN115701800A (en) | 2023-02-14 |
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| CN202211081002.9A Pending CN115701800A (en) | 2022-09-05 | 2022-09-05 | In-vitro blood pump system for on-line instant obtaining blood parameters |
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Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100036486A1 (en) * | 2008-08-05 | 2010-02-11 | Mazur Daniel E | Apparatus and Method for Monitoring and Controlling Extracorporeal Blood Flow Relative to Patient Fluid Status |
| US20100222878A1 (en) * | 2009-02-27 | 2010-09-02 | Thoratec Corporation | Blood pump system with arterial pressure monitoring |
| CN107080870A (en) * | 2016-02-16 | 2017-08-22 | 上海微创医疗器械（集团）有限公司 | Blood pump and making assisted circulation of ventriculus cordis device |
| US20200030510A1 (en) * | 2018-07-30 | 2020-01-30 | Cardiovascular Systems, Inc. | Intravascular pump with proximal and distal pressure or flow sensors and distal sensor tracking |
| CN115282465A (en) * | 2022-08-16 | 2022-11-04 | 苏州心擎医疗技术有限公司 | Online instant feedback control in-vitro blood pump system based on blood pressure |
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- 2022-09-05 CN CN202211081002.9A patent/CN115701800A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100036486A1 (en) * | 2008-08-05 | 2010-02-11 | Mazur Daniel E | Apparatus and Method for Monitoring and Controlling Extracorporeal Blood Flow Relative to Patient Fluid Status |
| US20100222878A1 (en) * | 2009-02-27 | 2010-09-02 | Thoratec Corporation | Blood pump system with arterial pressure monitoring |
| CN107080870A (en) * | 2016-02-16 | 2017-08-22 | 上海微创医疗器械（集团）有限公司 | Blood pump and making assisted circulation of ventriculus cordis device |
| US20200030510A1 (en) * | 2018-07-30 | 2020-01-30 | Cardiovascular Systems, Inc. | Intravascular pump with proximal and distal pressure or flow sensors and distal sensor tracking |
| CN115282465A (en) * | 2022-08-16 | 2022-11-04 | 苏州心擎医疗技术有限公司 | Online instant feedback control in-vitro blood pump system based on blood pressure |
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Address after: Room 801, 802, 803, 804, Building 7, No. 188 Fuchunjiang Road, High-tech Zone, Suzhou City, Jiangsu Province, 215163 Applicant after: Xinqing Medical (Suzhou) Co.,Ltd. Address before: 8th Floor, Building 7, No. 188, Fuchunjiang Road, Science and Technology City, High-tech Zone, Huqiu District, Suzhou City, Jiangsu Province 215163 Applicant before: SUZHOU XINQING MEDICAL TECHNOLOGY Co.,Ltd. |