CN115671570A

CN115671570A - Phototherapy breast patch

Info

Publication number: CN115671570A
Application number: CN202110848000.7A
Authority: CN
Inventors: 庞惠卿; 高东东
Original assignee: Beijing Summer Sprout Technology Co Ltd
Current assignee: Beijing Summer Sprout Technology Co Ltd
Priority date: 2021-07-29
Filing date: 2021-07-29
Publication date: 2023-02-03

Abstract

The invention discloses a phototherapy breast paste, which comprises at least one shell, a driving device and at least one OLED light-emitting panel; wherein the at least one housing is bowl-shaped or cone-shaped; the OLED light-emitting panel is integrated on the shell and emits light with a peak wavelength of 400-2000 nm; the OLED light-emitting panel emits light towards one side of a human body; the OLED light-emitting panel is electrically connected with the driving device. The shell material of the breast patch is preferably silica gel, and the breast patch can be directly pasted on the surface of a human breast without any other clothes for supporting; the breast patch may also further comprise a fastening means to enable it to be fitted to a bra for use in conjunction with a bra. The phototherapy breast patch not only has the effects of enlarging and tightening breasts, but also can be combined with an anti-cancer drug with a photosensitizer to carry out sensitization from the outside of the body to treat diseases such as breast cancer and the like.

Description

Phototherapy breast paste

Technical Field

The invention relates to a phototherapy breast patch. And more particularly, to a phototherapy patch using an OLED light emitting panel as a light source.

Background

Technologies such as Low Light Laser Treatment (Low Light Laser Treatment) and photobiological modulation (PBM) appear in the middle and later stages of the 20 th century, and both of them are applied to the medical field by using illumination as a means for treating diseases (Michael r. Various studies have shown that red to near infrared illumination is found to be helpful in promoting the regeneration of tissues such as collagen and skin cells, and can be applied in the fields of anti-wrinkle cosmetology, wound healing promotion, spot removal, scar elimination, etc. (Chan Hee Nam et al, dermatologic Surgery,2017, 371-380, daniel barolet, semin Cutan Med surg,2008,27 227-238, yongmin jeon, adv.mater.technol.2018, 1700391. Meanwhile, blue light irradiation is also the most effective means for treating pediatric jaundice at present, and a semiconductor Light Emitting Diode (LED) is used as a light sourcePhototherapy products integrated on flexible substrates are emerging (US 6811563B2, US6596016B1, US6974224B 2), even with commercial phototherapy blankets for treatment of neonatal jaundice, such as BiliTX products from Philips corporation (https:// www. Philips. Com. Cn/healthcare/product/HC 866437/BiliTX-). Furthermore, it has been found that photodynamics therapy (PDT) can be performed using light. As shown in fig. 4a, in PDT, light with a specific wavelength can excite a photosensitizer (for example, some drugs which are not effective originally can be activated by light to generate drug effect), so as to convert oxygen molecules into excited oxygen ions and kill target tissues and cells (including cancer cells, bacteria, fungi and viruses), thereby achieving the purpose of treating cancer and infection (Chen, journal of the SID 2018). Compared with the traditional surgical excision and chemotherapy, the targeted therapy becomes a new anti-cancer means in recent years, and the targeted therapy intervenes from a genetic level by judging the nature and the type of cancer cells, controls and kills specific cancer cells in a targeted manner, and can greatly reduce the pain and the influence of the surgery and the chemotherapy on patients. PDT may also be considered as one type of targeted therapy where a site is illuminated to activate a photosensitizer at that site to achieve a site-specific therapeutic effect. Fig. 4b shows the penetration depth of different wavelengths in the skin of a human body, and it can be seen that light with a wavelength of 600-1000nm can penetrate to a depth of 2-4mm (Daniel Barolet, semin Cutan Med Surg,2008, 27. FIG. 4c shows the absorption of light of different wavelength bands by different physiological substances (such as water, hemoglobin, oxyhemoglobin and melanin), and it can be seen that the optimal wavelength band window for passing through the skin tissue without loss is approximately between 600-1400nm (https://www.thepaleomom.com/joovv-red-light- therapy-for-weight-loss/)。

Breast cancer is increasingly being valued and more suitable treatments are being found, and PDT in combination with light as described above is expected to be a treatment for breast cancer.

On the other hand, with the change of aesthetic concept, more and more women follow the beauty of the body, and various breast-beautifying products are layered endlessly. For women who have a breast-feeding experience, preventing breast drop, maintaining breast shape and firmness are the primary goals of breast beautification. The red light to near infrared light is found to be helpful for promoting the regeneration of tissues such as collagen, skin cells and the like, can play a role in compacting the skin, and is suitable for being applied to a breast beautifying phototherapy product.

The OLED is a surface light source, a cold light source, is not glaring, and has a light and thin characteristic, so that it is very easily integrated on a flexible substrate. This makes OLEDs ideal light source options for wearable applications, and the related patent applications also cover various fields in recent years. Patent applications CN205108772U, CN204951964U and US2012155057A1 all mention that OLED light sources can be used as wearing products for medical treatment. US20090030489A1 and US20100179469A1 mention the use of OLEDs with wavelengths around 450nm as light sources for the treatment of pediatric jaundice, and the inventors' previous application CN111450421A proposed the conversion of flexible green OLEDs to blue light in combination with the conversion on TTA for the treatment of jaundice; application CN203694423U and prior application CN109173071A by the present inventors mentioned the use of OLEDs to prepare phototherapy masks; the previous patent applications CN111481833A, CN111514466A, CN111544774A and CN112754764A of the present inventor respectively mentioned the use of OLED for preparing hair growing cap, slimming shaping clothes, phototherapy socks and band-aid. Patent application US20090030489A1 also mentions a phototherapy bra, which can be woven with a series of LEDs into a textile, but such phototherapy bra is a whole, requires a bra carrier as a support, and cannot be detached and matched as desired like the breast patch described in the present invention. The main light source in this application is also an LED, which is a high-intensity point light source and generally generates heat. LED light sources generally incorporate heat sinks to reduce temperature, and the LEDs must be spaced apart for heat dissipation when used in an array. This results in three disadvantages of LEDs as light sources for phototherapy. First, it is bulky, because heat dissipation is considered, it must be added with a heat sink, and must be spaced from the human body for safety, and is uncomfortable to wear. Secondly, in the array arrangement, the LEDs are all independent at a certain position and have a distance from each other, which results in non-uniform light emission. During treatment, such uneven lighting may lead to uneven skin tone or require multiple treatments in different areas. Finally, to cover the entire treatment area, a large number of LEDs, sometimes as many as a hundred chips, need to be used, which increases the difficulty of LED screening, assembly and maintenance. However, the present invention does not have the above-mentioned problems because the OLED is used as a light source. Moreover, the invention discloses a specific technology of applying a two-dimensional plane light source to three-dimensional pasters, which is not involved in phototherapy products using LEDs as light sources.

CN105212291A discloses an intelligent underwear for women, especially a cotton piece with LED light source is arranged in the bra for treating hyperplasia of mammary glands. The intelligent underwear has a complete garment shape, and the light source cotton piece inside the bra adopts the LED lamp beads. CN201139874Y discloses a health underwear using semiconductor far infrared LED as light source, which mainly utilizes heat source to promote blood circulation, and does not utilize the therapeutic effect of visible light, and because of the volume and heat dissipation of LED, the underwear is heavy, not beautiful, and can affect the movement. According to the invention, the OLED, especially the flexible OLED light-emitting panel is adopted as the light source and integrated on the shell, so that the breast phototherapy device can be directly pasted on the breast for phototherapy without any other clothes for supporting, and the breast phototherapy device is simple and convenient to use, comfortable to wear and free from a sudden feeling. Although the inventor of the present invention has proposed the use of OLED lighting panel for shaping clothes in the previous application CN111514466A, the application focuses on integrating the independent OLED lighting panel into the elastic material to achieve the stretchable effect, and needs a whole body stretchable shell as the body of the plastic clothes, while the present invention only needs a bowl-shaped shell to cover the chest, does not need a stretching material, and can be freely detached or used with the existing bra.

Disclosure of Invention

In view of the above problems, the present invention is directed to a phototherapy patch that solves at least some of the above problems.

According to one embodiment of the present invention, a phototherapy patch is disclosed, comprising: at least one housing, at least one OLED light-emitting panel and a driving device;

wherein the at least one housing is bowl or cone shaped;

wherein the OLED light emitting panel is integrated on the housing and emits light comprising a peak wavelength in the range of 400-2000 nm;

the OLED light-emitting panel emits light towards one side of a human body;

wherein the OLED light-emitting panel is electrically connected with the driving device.

According to an embodiment of the present invention, there is also disclosed a method of using a phototherapy patch, the phototherapy patch comprising: at least one housing, at least one OLED light-emitting panel and a driving device; wherein the at least one housing is bowl or cone shaped; wherein the OLED light emitting panel is integrated on the housing and emits light comprising a peak wavelength in the range of 400-2000 nm; the OLED light-emitting panel emits light towards one side of a human body; wherein the OLED light-emitting panel is electrically connected with the driving device;

the use method comprises the following steps:

the method comprises the following steps: administering or injecting a drug containing a photosensitizer;

step two: wearing at least one phototherapy patch on an area to be treated;

step three: and driving the phototherapy breast paste to work.

The invention discloses a phototherapy breast patch, which comprises at least one shell, a driving device and at least one OLED light emitting panel, wherein the OLED light emitting panel is preferably a flexible light emitting panel and emits light with the peak wavelength of 400-2000 nm. The shell of the breast patch is preferably made of silica gel, can be directly pasted on the surface of a human breast and does not need any other clothes for supporting; the breast patch may also further comprise a fastening means to enable it to be fitted to a bra for use in conjunction with a bra. The phototherapy breast patch has effects of enlarging and tightening breast, and can be used in combination with anticancer drug with photosensitizer to perform sensitization from outside body to treat diseases such as breast cancer.

Drawings

FIGS. 1a-1c are schematic diagrams of single layer OLED device structures.

FIG. 2 is a schematic diagram of a stacked OLED device structure.

Fig. 3 is a schematic cross-sectional structure of an OLED light-emitting panel.

Fig. 4a is a schematic illustration of the PDT mechanism of action.

Fig. 4b is a schematic diagram of the penetration depth of light of different wavelengths through human skin.

Fig. 4c is a schematic diagram of the absorption of different wavelength bands of light by different physiological substances.

Fig. 5a-5c are schematic views of the structure of an OLED light-emitting panel.

Fig. 6a is a schematic structural diagram of a phototherapy patch 600.

Fig. 6b is a schematic cross-sectional structure diagram of the phototherapy patch 600.

Fig. 7 is a schematic structural diagram of a phototherapy patch 700.

Fig. 8 is a schematic view of the structure of the phototherapy patch fixed on a bra.

Detailed Description

As used herein, "top" means furthest from the substrate, and "bottom" means closest to the substrate. In the case where the first layer is described as being "disposed on" the second layer, the first layer is disposed farther from the substrate. Conversely, where a first layer is described as being "disposed" under a second layer, the first layer is disposed closer to the substrate. Other layers may be present between the first and second layers, unless it is specified that the first layer is "in contact with" the second layer. For example, a cathode may be described as "disposed on" an anode even though various organic layers are present between the cathode and the anode.

As used herein, the term "OLED device" includes an anode layer, a cathode layer, one or more organic layers disposed between the anode layer and the cathode layer. An "OLED device" can be bottom emitting, i.e., emitting light from the anode side, or top emitting, i.e., emitting light from the cathode side, or a transparent device, i.e., emitting light from both the anode and cathode.

As used herein, the term "OLED lighting panel" includes a substrate, an anode layer, a cathode layer, one or more organic layers disposed between the anode layer and the cathode layer, an encapsulation layer, and at least one anode contact and at least one cathode contact extending outside of the encapsulation layer for external access.

As used herein, the term "encapsulation layer" may be a thin film encapsulation having a thickness of less than 100 microns, which includes disposing one or more thin films directly onto the device, or may also be a cover glass (cover glass) adhered to a substrate.

As used herein, the term "flexible printed circuit" (FPC) refers to any flexible substrate coated with any one or combination of the following, including but not limited to: conductive lines, resistors, capacitors, inductors, transistors, micro-electro-mechanical systems (MEMS), etc. The flexible substrate of the flexible printed circuit may be plastic, thin glass, thin metal foil coated with an insulating layer, fabric, leather, paper, etc. A flexible printed circuit board is typically less than 1mm thick, more preferably less than 0.7mm thick.

As used herein, the term "light extraction layer" may refer to a light diffusing film, or other microstructure having light extraction effects, or a thin film coating having light outcoupling effects. The light extraction layer can be disposed on the substrate surface of the OLED, or can be in other suitable locations, such as between the substrate and the anode, or between the organic layer and the cathode, between the cathode and the encapsulation layer, on the surface of the encapsulation layer, and so forth.

As used herein, the term "independently driven" means that the operating points of two or more light emitting panels are separately controlled. Although the light emitting panels may be connected to the same controller or power line, there may be circuitry to divide the drive lines and power each panel without affecting each other.

As used herein, the term "light-emitting region" refers to a portion of the planar area where the anode, organic layer and cathode coincide together, and does not include a light extraction effect.

As used herein, the term "light emitting face" refers to the side of the light source that emits light, e.g., if the light source comprises a bottom-emitting OLED light emitting panel, the "light emitting face" comprises the side of the substrate away from the anode, and if a top-emitting device, the "light emitting face" comprises the side of the encapsulation layer away from the cathode.

As used herein, the term "single layer device" refers to a device having a single light-emitting layer and its associated transport layer, i.e., a "single layer device," with a light-emitting layer and its associated transport layer between a pair of cathodes and anodes.

As used herein, the term "stacked device" refers to a device structure having a plurality of light-emitting layers between a pair of cathode and anode, each light-emitting layer having its own independent hole transport layer and electron transport layer, each light-emitting layer and its associated hole transport layer and electron transport layer constituting a single light-emitting layer, the single light-emitting layers being connected with each other by a charge generation layer, and a device having such a plurality of single light-emitting layers is a "stacked device".

As used herein, a "light source lattice" refers to a plurality of light sources arranged repeatedly at a certain pitch, thereby forming a combination of a series of light sources; the arrangement may be an arrangement with equal spacing or an arrangement with unequal spacing.

As used herein, "light-emitting unit" refers to a smallest complete light-emitting device in a lattice arrangement, which may be a device or a panel (i.e., a light source), typically surrounded by non-light-emitting areas. The light-emitting units in a lattice may all have the same area or different areas.

wherein the at least one housing is bowl or cone shaped;

wherein the OLED light-emitting panel emits light towards one side of the human body;

According to one embodiment of the invention, wherein the housing comprises a holding housing.

According to one embodiment of the invention, wherein the housing further comprises a protective housing.

According to an embodiment of the present invention, the material of the portion of the housing contacting with the human body is selected from silicone.

According to one embodiment of the invention, the housing is capable of being applied directly to human skin.

According to one embodiment of the invention, wherein the bowl opening diameter of the housing is not more than 12cm.

According to one embodiment of the invention, the diameter of the bowl opening of the housing is not more than 10cm.

According to one embodiment of the invention, wherein the diameter of the bowl opening of the housing is not more than 8cm.

According to an embodiment of the invention, wherein the OLED light-emitting panel is flexible.

According to an embodiment of the invention, wherein the drive means comprises any one or more of the following components: the battery, the circuit board, the lead wire, wireless charging device, bluetooth communication device.

According to one embodiment of the present invention, the driving device is wirelessly connected to an external electronic device.

According to an embodiment of the present invention, the shell further comprises a fastening device, the fastening device is connected with the bra, and the fastening device is selected from the group consisting of a strap, a hook-and-loop fastener, a zipper, a latch, a hook, and a combination thereof.

According to one embodiment of the invention, wherein the shell further comprises a fastening means, said fastening means being connected to the brassiere, said fastening means being selected from the group consisting of hooks.

According to one embodiment of the invention, the plaster comprises at least two shells.

According to one embodiment of the invention, the plaster comprises at least two shells, and the plaster further comprises a connecting device capable of connecting the two shells.

According to one embodiment of the present invention, wherein the connecting means is selected from the group consisting of a strap, a hook and loop fastener, a zipper, a snap, a hook and a combination thereof.

According to one embodiment of the invention, wherein said connecting means is selected from a lock.

According to one embodiment of the invention, the phototherapy patch comprises a plurality of OLED light emitting panels, and the light emitting areas of the plurality of OLED light emitting panels are the same.

According to one embodiment of the invention, the light emitting areas of the plurality of OLED light emitting panels are fan-shaped, triangular, bar-shaped, cone-shaped, and trapezoid-shaped.

According to an embodiment of the present invention, there is also disclosed a method for using the phototherapy patch according to any one of the above embodiments, comprising the following steps:

step two: wearing at least one phototherapy patch on the area to be treated;

step three: and driving the phototherapy patch to work.

According to one embodiment of the invention, the absorption wavelength of the photosensitizer coincides with the emission wavelength of at least one of the OLED light emitting panels.

According to one embodiment of the invention, the driving device of the phototherapy patch is wirelessly connected with external electronic equipment; the driving in step three further comprises the following steps:

step A: downloading and installing an application program in the external electronic equipment;

and B: opening an application program and wirelessly connecting the phototherapy breast patch;

step C: controlling the phototherapy patch to work using an application.

A schematic diagram of a typical single-layer OLED device 100 is shown in fig. 1 a. The OLED device 100 includes an anode layer 101, a Hole Injection Layer (HIL) 102, a Hole Transport Layer (HTL) 103, an Electron Blocking Layer (EBL) 104, an emission layer (EML) 105, a Hole Blocking Layer (HBL) 106, an Electron Transport Layer (ETL) 107, an Electron Injection Layer (EIL) 108, a cathode layer 109, and a capping layer (CPL) 110. In a bottom emission device, the anode layer 101 is a transparent or translucent material, including but not limited to ITO, IZO, moOx (molybdenum oxide), etc., which has a transparency generally greater than 50%, preferably greater than 70%; the cathode layer 109 is a material having a high reflectivity including, but not limited to, al, ag, etc., the reflectivity being greater than 70%, preferably greater than 90%. In a top-emitting device, the anode layer 101 is a material or combination of materials with high reflectivity, including but not limited to Ag, ti, cr, pt, ni, tiN, and combinations of the above with ITO and/or MoOx (molybdenum oxide), typically with a reflectivity of greater than 50%; preferably, greater than 80%; more preferably, greater than 90%; and the cathode layer 109 should be a semi-transparent or transparent conductive material including, but not limited to, mgAg alloy, moOx, yb, ca, ITO, IZO or combinations thereof, typically having a transparency greater than 30%; preferably, greater than 50%. In a double-sided light emitting device, the anode layer 101 and the cathode layer 109 are both made of transparent or translucent materials, so that the device can emit light from both sides of the anode and the cathode, respectively. In this case, the transparency of the two electrode layers can be adjusted to control a side to emit more or less light, for example, if the anode layer has a higher transmittance than the cathode layer, the anode layer emits more light than the cathode layer, and vice versa. The electron injection layer 108 may be a single layer of metal Yb or may be an organic material LiQ. The light-emitting layer 105 also typically comprises at least one host material and at least one light-emitting material, while the electron blocking layer 104 and the hole blocking layer 106 are optional layers, and the capping layer 110 is not required in bottom-emitting devices. The hole injection layer 102 may be a single layer of material, such as the commonly used HATCN; the hole injection layer 102 may also be a hole transport material doped with a p-type conductivity dopant material in a proportion, typically not higher than 5%, usually between 1% and 3%. FIG. 1b shows a schematic diagram of a multicolor OLED device 130, which may include a light-emitting layer 1051 and a light-emitting layer 1052, where the peak wavelength of the light-emitting layer 1051 may be between 600-750nm (red light emission) and the peak wavelength of the light-emitting layer 1052 may be between 750-1400nm (near infrared light emission), with the remaining layers unchanged. Note that the order of the two light-emitting layers may be reversed, that is, the light-emitting layer 1051 emits near-infrared light and the light-emitting layer 1052 emits red light. The OLED device with the structure can emit red light and near infrared light simultaneously. FIG. 1c shows a schematic diagram of a structure of a variable color OLED device 120, which has a light-emitting layer 1053, a light-emitting layer 1055 and an adjustment layer 1054. The adjusting layer 1054 can adjust and control the movement of electron holes under different current densities, thereby realizing the adjustment and control of colors. For example, where the peak wavelength of the light emitting layer 1053 may be between 600-750nm (red light emitting), the peak wavelength of the light emitting layer 1055 may be between 750-1400nm (near infrared light emitting), at low current density the exciton recombination zone is predominantly near the cathode side, i.e., in the light emitting layer 1053, the OLED device 120 may emit red light; when the injection is gradually increased and the voltage and current density are increased, the exciton recombination region moves to the anode side and finally enters the near light emitting layer 1055, and the oled device 120 emits near infrared light. Of course, the light-emitting layer 1053 may emit near-infrared light and the light-emitting layer 1055 may emit red light, or vice versa. Reference may be made in particular to the present inventors' previous patent applications CN111081891A and CN111081892A for the structure and use of the adjustment layer of a variable color OLED device.

A schematic diagram of a typical stacked OLED device 200 is shown in fig. 2, and includes an anode layer 201, a first light emitting unit 202, a Charge Generation Layer (CGL) 203, a second light emitting unit 204, and a cathode layer 205. The first light emitting unit 202 and the second light emitting unit 204 may further include a series of organic layers from 102 to 108 in the single-layer light emitting device 100, and the light emitting layers of the first light emitting unit and the second light emitting unit may be the same or different. The first light emitting unit 202 and the second light emitting unit 204 can emit lights of the same color, such as red lights with peak wavelengths between 600 nm and 750 nm; the first light emitting unit 202 and the second light emitting unit 204 can also emit light of different colors, for example, the first light emitting unit 202 emits red light, and the second light emitting unit 204 emits near infrared light with a peak wavelength between 750nm and 1400nm, in which case the device 200 can emit red light and near infrared light at the same time. The charge generation layer 203 is generally made of an n-type material and a p-type material, and may be supplemented with a buffer layer, as described in patent application US20210119162 A1. If the stacked device is a top-emitting device, a capping layer (not shown) may also be added over the cathode layer 205. Fig. 2 shows a two-unit stacked device, and a third light-emitting unit and a second charge generation layer can be added to form a three-unit stacked device. The fabrication of both single and stacked OLED devices is well known in the art and will not be described in detail herein.

A schematic cross-sectional view of an OLED lighting panel is shown in fig. 3. The OLED light emitting panel 300 includes a substrate 301, an OLED device 302, a pair of contact electrodes 304 electrically connected to the OLED device 302, and an encapsulation layer 303 (but exposing the contact electrodes 304). The substrate 301 may be a rigid glass, preferably flexible, such as ultra-thin flexible glass, more preferably a non-brittle material, including but not limited to plastic (PET, PEN, PI), textile, leather, paper, metal foil, or a combination thereof. In particular, the substrate 301 may be a material (e.g., PI, polyimide-based material) that is coated on the supporting substrate in the form of a solution in advance, cured and planarized for device fabrication. After the device is prepared, it is peeled off from the supporting substrate using a laser and transferred to other flexible films as needed. The substrate 301 may be additionally coated with a moisture barrier layer (not shown). OLED device 302 can be a bottom emitting device or a top emitting device, with a top emitting device being preferred because of its higher luminous efficiency. OLED device 302 can be a single layer structure or a stacked layer structure, with a stacked layer structure being preferred because it has a longer lifetime at the same brightness and because a thicker film layer is beneficial for increasing production yield. The organic material in the OLED device 302 may be formed by evaporation in a vacuum chamber by thermal evaporation (vacuum evaporation), or may be formed partially or even entirely by a solution process, including but not limited to ink jet printing (ink jet printing), spin coating, organic vapor spray printing (OVJP), and the like. The encapsulation layer 303 may be glass adhered to the device by UV curable adhesive, preferably a flexible encapsulation layer, also called thin film encapsulation layer, generally having a thickness of 5 μm or more, such as a single inorganic thin film, or an alternating multilayer structure of organic and inorganic thin films, and is formed by PECVD, ALD, printing, spin coating, etc. The contact electrode 304 may comprise at least one anode contact and one cathode contact. On this basis, light extraction layers, front and rear cover films, FPC boards, etc. may also be added, specific descriptions may be found in patent application US20190376650A1, which is incorporated by reference in its entirety, which is not within the scope of the detailed description of this application. Such an OLED light-emitting panel is an OLED light source when electrically connected to an external power (regardless of whether it is in an on or off state), and is one of the basic components of the present invention. The OLED light-emitting panel used in the present invention is preferably a flexible light-emitting panel, i.e., having a flexible substrate and a flexible film package. The OLED devices in the above-described OLED light-emitting panels all use common organic layers, in particular having common organic light-emitting layers, i.e. non-pixilated, and can only emit light of one color at a fixed operating point. The above-mentioned OLED light-emitting panel may emit at least one light having a peak wavelength of 400 to 2000nm, preferably the above-mentioned OLED light-emitting panel may emit at least one light having a peak wavelength of 450 to 1000nm, more preferably at least one light having a peak wavelength of 600 to 970 nm.

The phototherapy breast patch can emit light with different colors to match different treatment requirements, for example, red light or near infrared light is used for chest compaction treatment, and the light with the absorption wavelength of the photosensitizer is emitted to match drug treatment. There are several ways to achieve light with a variety of different wavelength bands: the first is to design a pixelized layout on the same OLED light-emitting panel and then drive each pixel independently, or group pixels and then drive different groups independently. Preferably, a flexible OLED light-emitting panel is used, i.e. encapsulated with a flexible substrate and a thin film. The pixels here usually have a light-emitting area in the order of millimetres, i.e. a minimum dimension greater than 1mm ² Preferably greater than 5mm ² . For example, a flexible OLED light-emitting panel 500 shown in fig. 5a may include a flexible OLED substrate 501 on which a series of OLED devices 502 are patterned, and these devices share the same thin film encapsulation layer 503, where each light-emitting unit is an OLED device, and the whole flexible OLED light-emitting panel is a light source. In this case, the metal wires may be arranged on the panel at the same time of preparing the anode or the cathode for electrically connecting the OLED devices 502, and the method of the metal wires is well known in the art and will not be described herein. The circuit control system controls different OLED devices to emit light of different colors or emit light of the same colorThe devices operate at different currents to achieve multiple colors. A variation of this is a flexible OLED light emitting panel 510 as shown in fig. 5b comprising a flexible OLED substrate 501, a series of OLED devices 502, but each device enjoys a separate encapsulating layer 513, and preferably a thin film encapsulating layer. At this time, the different OLED devices 502 can be connected through not only metal wiring but also an FPC board, which greatly improves the possibility of conductivity and circuit complexity. Also, a single or multiple OLED devices 502 can be independently driven through these electrical connections. Under the two conditions, if light with different colors is emitted, different device structures can be evaporated on different OLED devices by using a metal mask, particularly, the material of a light emitting layer is changed; it is also possible to refer to the arrangements described in applications CN111081892A and CN111081891A, all using the same structure of independent units, multiple light emitting layers, with the variation of the colour being achieved by the movement of the recombination zones at different working points. Alternatively, individual OLED light emitting panels may be arranged in an array, as shown in fig. 5c, where each light emitting panel comprises an individual substrate 521, an OLED device 502 and an individual encapsulating layer 513. The advantage of this arrangement is that the non-flexible OLED light-emitting panel and/or the non-flexible encapsulation layer can be selected, and the light source formed into the array still has certain flexibility as long as the area is small enough. The individual OLED light emitting panels may be cut from the same motherboard, for example, using the same individual unit multi-light emitting layer structure, or may be reassembled by selecting different structures of devices from different motherboards. The scheme has the advantages that the device can be screened, the yield is improved, and the color diversity of products is also improved. The independent light-emitting panel shown in fig. 5c may be arranged and combined through an FPC or front and back cover films, etc. as required to form a dot matrix physically connected to each other, which may specifically refer to the method disclosed in CN208750423U, which is not within the scope of the detailed description of the present application and is not described herein again. Also, the panels may be independently controlled to provide different operating currents. The array arrangement can realize multicolor luminescence and partitionAnd the power consumption can be further reduced by controlling and locally illuminating, and the energy is saved.

The patch of the present invention is three-dimensional in shape, as shown in fig. 6 a. The paste 600 comprises a shell 601 and a series of OLED light-emitting panels 602, wherein the shell 601 of the paste 600 is in a bowl-shaped or cone-shaped form, and the diameter of a bowl opening (the diameter of a circle at the bottom of the bowl opening) or the diameter of a cone bottom is not more than 12cm, preferably not more than 10cm, and more preferably not more than 8cm. Here, the cone shape may have a conventional closed apex, or may be other designs, such as a hole to expose the nipple of the human body to avoid compression (especially for lactating women), or a spherical shape to match the shape of the nipple of the human body. The OLED light-emitting panel is generally planar, and may be formed by integrating a plurality of OLED light-emitting panels, preferably flexible OLED light-emitting panels, on the housing in a shape selected to provide a three-dimensional effect. The light emitting area of the OLED light emitting panel 602 in fig. 6a has a fan-shaped pattern, which is only illustrated here, but the light emitting area of the OLED light emitting panel may have other patterns, such as triangle, strip, cone, trapezoid, etc. If a cone-like form is used, the OLED light-emitting panel may be continuous throughout the housing to achieve large area phototherapy; or the shell can be arranged at intervals or in an array, and phototherapy can be performed only at the required part. At the position without an OLED panel or device, the material with good air permeability can be selected as the shell, so that the air permeability can be ensured while the phototherapy is worn for a long time. Fig. 6b shows a schematic cross-sectional structure diagram 610 of the paste 600, wherein the housing 601 may further include two parts, one part is a supporting housing 6101 and the other part is a protecting housing 6102, the two parts wrap the OLED light emitting panel 602 therein, only the contact electrode 603 is left for connecting the circuit board 604, and the OLED light emitting panel 602 emits light toward the protecting housing 6102 side. The protection housing 6102 is a side contacting with the skin of the human body, and is preferably made of a medical silica gel material, which is transparent and naturally adheres to the skin surface. The supporting housing 6101 mainly plays a role of supporting and integrating each OLED light emitting panel 602, and the material of the supporting housing includes, but is not limited to, plastic, rayon, silica gel, and the like, and may also be a textile of natural material, including, but not limited to, cotton, hemp, yarn, silk, brocade, satin, and the like. The protection housing 6102 and/or the support housing 6101 may also have a certain thickness to achieve a certain breast augmentation effect. The housing 601 may further comprise a separate film patch that can be attached to the protection housing 6102 when not in use to prevent dust and adhesion (not shown). The plaster 600 further comprises a driving device, which includes but is not limited to one or a combination of several of the following: battery, circuit board, lead wire, wireless charging device, bluetooth communication device etc.. The battery and the circuit board in the driving device can directly supply power to the OLED light-emitting panel, and can control the brightness of the panel and control the blocking of the panel; the driving device can also use a Bluetooth communication device to be connected with other intelligent electronic equipment such as a mobile phone and the like to wirelessly control the OLED light-emitting panel, wherein the driving device comprises but is not limited to a switch, a brightness control device and a partition control device; aiming at different treatment requirements of different parts, the driving device can be used for driving the panel to emit light containing different peak wavelengths. The drive means may be integrated in the housing 601, preferably in the support housing 6101. Such a patch can be used alone, and when in use, the protection housing 6102 is directly attached to the area of the chest to be treated, and the OLED light-emitting panel 602 is turned on by using the driving device. Of course, two identical patches (a pair) may be used to treat both breasts simultaneously. If the anti-cancer treatment is carried out, the breast paste can also be combined with a medicament containing a photosensitizer for treatment. The medicine can enter the body in advance in a form of oral administration or injection, and when the breast patch works, the light wave emitted by the OLED can be absorbed by the photosensitizer in the medicine and promotes the photosensitizer to generate chemical reaction and directly or indirectly act on cancer cells, so that the treatment effect is achieved. Here, the wavelength emitted from the OLED light emitting panel 602 is coincident with the absorption wavelength of the photosensitizer, and preferably, the peak wavelength emitted from the OLED light emitting panel 602 is completely coincident with the absorption wavelength of the photosensitizer.

In one embodiment, two breast patches may also be used in conjunction. The plaster 700 shown in fig. 7 comprises two separate plasters 710, each plaster 710 in turn comprising a housing 7101 and a series of OLED light emitting panels 7102. The pair of breast patches 710 are connected by a connecting device 701, and the connecting device 701 may be a locking device as shown in fig. 7, or may be in other forms, including but not limited to a strap, a hook and loop fastener, a zipper, etc. The connecting device can enable the two breast patches to be more fixed during use and can also play a role in breast shaping.

Fig. 8 shows another embodiment of phototherapy patches 800, which includes a bra 801, a pair of phototherapy patches 810, and a fixing device 8103 for fixing the phototherapy patches 810 on the bra 801. Brassiere 801 is an existing conventional brassiere that does not contain any light source and that can be worn directly. Phototherapy patch 810 also further comprises a housing 8101 and a series of OLED light emitting panels 8102. The fixation device 8103 may be of any form, including but not limited to: a bandage, a magic tape, a zipper, a lock catch, a hook and the like, and the hook is taken as an illustration in figure 8. The benefit of this kind of scheme can be fixed phototherapy breast and use on any has brassiere, and the stationary effect is better, does not influence daily dress yet simultaneously.

The phototherapy breast paste disclosed by the invention integrates a series of OLED light-emitting panels on a shell, preferably a flexible light-emitting panel, so that the phototherapy effect is achieved. Particularly, the phototherapy breast patch preferably uses a silica gel material as the shell, so that the phototherapy breast patch can be directly pasted on the skin of a human body, and is light and comfortable to wear. The milk paste is integrated with a driving device which can directly supply power to the OLED light-emitting panel, and can also be connected to other electronic equipment such as a mobile phone through wireless devices such as Bluetooth and the like to control the milk paste.

It should be understood that the various embodiments described herein are illustrative only and are not intended to limit the scope of the invention. Thus, the invention as claimed may include variations from the specific embodiments and preferred embodiments described herein, as will be apparent to those skilled in the art. Many of the materials and structures described herein may be substituted with other materials and structures without departing from the spirit of the present invention. It should be understood that various theories as to why the invention works are not intended to be limiting.

Claims

1. A phototherapy patch, comprising: at least one housing, at least one OLED light-emitting panel and a driving device;

wherein the at least one housing is bowl or cone shaped;

the OLED light-emitting panel emits light towards one side of a human body;

2. The phototherapy patch of claim 1, wherein the housing comprises a support housing.

3. The phototherapy patch of claim 1 or 2, wherein the housing further comprises a protective housing.

4. The phototherapy patch of claim 1, wherein the portion of the shell in contact with the human body is made of a material selected from the group consisting of silica gel.

5. The phototherapy patch of claim 1, wherein the housing is capable of being directly applied to human skin.

6. The phototherapy patch of claim 1, wherein the bowl opening diameter of the housing is no greater than 12cm, preferably no greater than 10cm, more preferably no greater than 8cm.

7. The phototherapy patch of claim 1, wherein the OLED light emitting panel is flexible.

8. The phototherapy patch of claim 1, wherein the drive means comprises any one or more of the following components: the battery, circuit board, lead wire, wireless charging device, bluetooth communication device.

9. The phototherapy patch of claim 1, wherein the driving device is wirelessly connected to an external electronic device.

10. The phototherapy breast patch of claim 1, wherein the housing further comprises a fastening device, the fastening device being connected to the bra, the fastening device being selected from the group consisting of a strap, a velcro tape, a zipper, a latch, a hook, and combinations thereof, preferably a hook.

11. The phototherapy breast patch of claim 1, wherein the breast patch comprises at least two shells, preferably the breast patch further comprises a connecting means, which is capable of connecting the two shells.

12. The phototherapy patch of claim 11, wherein the connection means is selected from the group consisting of a strap, a velcro, a zipper, a snap, a hook and a combination thereof, preferably a snap.

13. The phototherapy patch of claim 1, wherein the phototherapy patch comprises a plurality of OLED light emitting panels having the same light emitting area.

14. The phototherapy paster of claim 13, wherein the light emitting areas of the plurality of OLED light emitting panels are in a fan shape, a triangle shape, a strip shape, a cone shape, and a trapezoid shape.

15. A method of using the phototherapy patch of claim 1, comprising the steps of:

step two: wearing at least one phototherapy patch on the area to be treated;

step three: and driving the phototherapy breast paste to work.

16. The method of claim 15, wherein the absorption wavelength of the photosensitizer coincides with the emission wavelength of at least one of the OLED light-emitting panels.

17. The use method of the phototherapy patch of claim 15 or 16, wherein the driving device of the phototherapy patch is wirelessly connected with an external electronic device; the driving in step three further comprises the steps of:

step A: downloading and installing an application program in an external electronic device;

and C: controlling the phototherapy patch to work using an application program.