CN115655365A - System, device and method integrating environment monitoring and pipettor tightness detection - Google Patents

System, device and method integrating environment monitoring and pipettor tightness detection Download PDF

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Publication number
CN115655365A
CN115655365A CN202211325462.1A CN202211325462A CN115655365A CN 115655365 A CN115655365 A CN 115655365A CN 202211325462 A CN202211325462 A CN 202211325462A CN 115655365 A CN115655365 A CN 115655365A
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China
Prior art keywords
air
control chip
measurement
circuit
sensor
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CN202211325462.1A
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Chinese (zh)
Inventor
佟林
王环宇
张竟月
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Fushun Product Quality Supervision And Inspection Institute
National Institute of Metrology
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Fushun Product Quality Supervision And Inspection Institute
National Institute of Metrology
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Priority to CN202211325462.1A priority Critical patent/CN115655365A/en
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Abstract

The invention discloses a system, a device and a method integrating environment monitoring and pipettor sealing performance detection, comprising a control chip; the control chip is connected with the power module through a circuit; the control panel button is connected with the control chip through a circuit; the air parameter sensor is connected with the control chip through a circuit; the vacuum pump is connected with the control chip through a circuit, and the vacuum pump is communicated and assembled with a test pipeline; the pipeline pressure sensor is connected with the control chip through a circuit, and the pipeline pressure sensor is correspondingly assembled on the test pipeline; the storage module is connected with the control chip through a circuit, and data intercommunication sharing is established between the storage module and the control chip. The problems that the existing pipette tightness inspection equipment is realized by purchasing relevant accessories after assembly, the organization steps are complex, the detection efficiency is low, the occupied area is large during operation, only a single function of tightness inspection can be completed, flexible application is difficult to realize, and the applicability of the whole function is poor are solved.

Description

System, device and method integrating environment monitoring and pipettor tightness detection
Technical Field
The invention relates to the technical field of experimental detection equipment, in particular to a system, a device and a method integrating environment monitoring and pipette tightness detection.
Background
In the prior art, the adhesion test of the pipettor still adopts an original bubble observation method, that is, the pipettor to be tested, on which the suction head is installed, is connected to the test port of the vacuum pump, and the air-extracting device of the vacuum pump is started, so that the negative pressure value in the air area at the upper part of the reagent bottle reaches a predetermined value and is balanced, and then is continued for a predetermined time, at this time, no bubble is generated at the lower end of the glass tube of the pipettor to be tested, and the adhesion of the pipettor to be tested is qualified.
The process of above-mentioned adaptation inspection is realized after the equipment of purchase relevant accessory, and whole step is complicated loaded down with trivial details, and is inefficient, and area is great during the operation moreover, also can only accomplish the single function of adaptation inspection simultaneously, is difficult to effectively realize nimble application, and whole functional is not high, and functional applicability is relatively poor.
Disclosure of Invention
Therefore, the invention provides a system, a device and a method integrating environment monitoring and pipette tightness detection, and aims to solve the technical problems that in the prior art, the tightness detection process of a pipette is realized by purchasing related accessories and assembling, the steps are complicated, the efficiency is low, the occupied area is large during operation, only a single function of tightness detection can be completed, flexible application is difficult to realize, and the applicability of the whole function is poor.
In order to achieve the above purpose, the invention provides the following technical scheme:
a system integrating environment monitoring and pipettor sealing performance detection comprises a control chip, a power module, a control panel button, a storage module, an air parameter sensor, a vacuum pump and a pipeline pressure sensor, wherein the control chip is connected with the power module;
the control chip is connected with the power module through a circuit;
the control panel button is connected with the control input end of the control chip through a circuit;
the air parameter sensor is connected with the control input end of the control chip through a circuit;
the vacuum pump is connected with the control output end of the control chip through a circuit, the vacuum pump is communicated and assembled with a test pipeline, and the test pipeline is provided with a test port for connecting the pipettor;
the pipeline pressure sensor is connected with the control input end of the control chip through a circuit, and the pipeline pressure sensor is correspondingly assembled on the test pipeline;
the storage module is connected with the control chip through a circuit, and data intercommunication sharing is established between the storage module and the control chip.
On the basis of the technical scheme, the invention is further explained as follows:
as a further aspect of the present invention, the air parameter sensor includes an air pressure sensor, an air density sensor, an air humidity sensor and an air temperature sensor;
the air pressure sensor, the air density sensor, the air humidity sensor and the air temperature sensor are respectively connected with the control input end of the control chip through circuits;
the air pressure value of air pressure sensor real-time supervision experiment environment air, the air density of air density sensor real-time supervision experiment environment air, the air humidity of air humidity sensor real-time supervision experiment environment air, the air temperature of air temperature sensor real-time supervision experiment environment air.
As a further scheme of the invention, the device also comprises a display screen;
the display screen is connected with the control output end of the control chip through a circuit;
the display screen displays the air pressure value, the air density value, the air humidity value, the air temperature value, the pressure value, the measurement countdown, the pressure difference value and the measurement result data of the experimental environment in real time.
As a further aspect of the invention, the pressure value is displayed as a currently measured negative pressure value within the pipette channel.
As a further aspect of the invention, the measurement countdown is displayed as a measurement remaining time, and the timing is started when the negative pressure reaches-40 kPa during the measurement.
As a further aspect of the present invention, the pressure difference is displayed as an absolute value of the pressure difference before and after the measurement;
and displaying failed or pass identification on the bottom of the display screen according to the measurement result, and identifying the latest measurement result.
As a further scheme of the invention, the device also comprises a timing module;
the timing module is connected with the control chip through a circuit, and the timing module is used for timing measurement starting time and/or measurement remaining time.
A method for detecting the adhesion of a liquid transfer device by using the system integrating environment monitoring and adhesion detection of the liquid transfer device comprises the following steps:
description of procedure for detection of pipette adhesion:
pressing a menu key of a control panel button to select a measurement mode;
connecting a port of a test pipeline communicated with a vacuum pump with a pipettor to be tested, and then pressing a confirmation key to start measurement;
the control chip controls the vacuum pump to pump the liquid transfer pipe to negative pressure of-40 kPa;
the pipeline pressure sensor starts to measure until negative pressure of-40 kPa is reached, and meanwhile, the timing module starts to count down;
when the absolute value of the pressure difference before and after measurement is not more than 5kPa after the countdown is finished, the measurement is passed, and the tightness of the pipettor to be measured is qualified; otherwise, the measurement fails (failed), and the tightness of the liquid transfer device to be measured is not qualified;
and pressing a determination key on the measurement interface to perform measurement again.
A device for carrying the system for integrating environmental monitoring and pipette adhesion detection, comprising:
the device comprises a shell, a first end cover, a second end cover, a fastening screw, a display screen and a control panel button;
the first end cover and the second end cover are correspondingly buckled one by one respectively and are fixedly connected to two side parts of the shell through the fastening screws;
the first end cover and the second end cover are fixedly connected with support legs respectively;
dispensing sealing rings are arranged among the first end cover, the second end cover and the shell;
the display screen and the control panel buttons are respectively assembled on the shell.
A self-checking method of the device comprises the following steps:
pressing a menu key in a control panel button of a shell main interface, selecting self-checking at the menu key, and pressing a confirm key to enter a self-checking mode;
in the self-checking mode, displaying a real-time pressure value in a test pipeline connected with the vacuum pump at present, opening the vacuum pump by a confirmation key, and blocking a test port of the test pipeline to enable a negative pressure state to be formed in the test pipeline;
and (4) closing the vacuum pump in a negative pressure state, observing data change, and detecting whether the inside of the device leaks air.
The invention has the following beneficial effects:
this system and device cooperate through each air sensor and control chip and correspond respectively and realize air pressure, air density, air humidity and the air temperature monitoring to experimental environment, cooperate with each other with the help of vacuum pump and pipeline pressure sensor simultaneously and effectively accomplish and detect the pipettor driving fit to this is showing and has promoted the function integration level, has guaranteed function application flexibility and function practicality.
Drawings
In order to clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the embodiments or the technical solutions in the prior art will be briefly introduced, and the structures, the proportions, the sizes, and the like shown in the specification are only used for matching with the contents disclosed in the specification, so that those skilled in the art can understand and read the modifications of any structures, the changes of the proportion relationships, or the adjustments of the sizes, without affecting the functions and the achievable purposes of the present invention, and still fall within the scope of the technical contents disclosed in the present invention.
Fig. 1 is a schematic diagram of an overall control principle of a system integrating experimental environment monitoring and pipette adhesion detection provided in an embodiment of the present invention.
Fig. 2 is a schematic top view of a device integrating experimental environment monitoring and pipette adhesion detection according to an embodiment of the present invention.
Fig. 3 is a schematic side view of a device integrating experimental environment monitoring and pipette adhesion detection according to an embodiment of the present invention.
Fig. 4 is a schematic bottom view of a device integrating experimental environment monitoring and pipette tightness detection according to an embodiment of the present invention.
In the drawings, the reference numbers indicate the following list of parts:
a housing 1; a first end cap 2; a support leg 3; a second end cap 4; dispensing a sealing ring 5; a fastening screw 6; a display screen 7; the panel buttons 8 are manipulated.
Detailed Description
The present invention is described in terms of particular embodiments, other advantages and features of the invention will become apparent to those skilled in the art from the following disclosure, and it is to be understood that the described embodiments are merely exemplary of the invention and that it is not intended to limit the invention to the particular embodiments disclosed. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
In the present specification, the terms "upper", "lower", "left", "right" and "middle" are used for clarity of description only, and are not used to limit the scope of the present invention, and the relative relationship between the terms and the relative positions may be changed or adjusted without substantial technical change.
As shown in fig. 1, an embodiment of the present invention provides a system integrating experimental environment monitoring and pipette tightness detection, including a control chip, a power module, a control panel button, a storage module, a timing module, an air pressure sensor, an air density sensor, an air humidity sensor, an air temperature sensor, a vacuum pump, a display screen, and a pipeline pressure sensor, for respectively and correspondingly monitoring air pressure, air density, air humidity, and air temperature in an experimental environment through cooperation between each air sensor and the control chip, and meanwhile, by means of cooperation between the vacuum pump and the pipeline pressure sensor, tightness detection of pipettors is effectively completed, so that function integration is significantly improved, and flexibility of function application is ensured. The specific settings are as follows:
the control chip is connected with the power module through a circuit and is used for supplying electric energy to the control chip and the whole system by means of the power module.
The control panel button is connected with the control input end of the control chip through a circuit and used for being used as the working control instruction input end of the control chip.
Air pressure sensor air density sensor air humidity transducer with air temperature sensor respectively with link to each other through the circuit between control chip's the control input for atmospheric pressure value through air pressure sensor real-time supervision experiment environment air, through the air density of air density sensor real-time supervision experiment environment air, through the air humidity of air humidity sensor real-time supervision experiment environment air, and through the air temperature of air temperature sensor real-time supervision experiment environment air, effectively realize to each item parameter monitoring function of system to experimental environment with this.
The vacuum pump is connected with the control output end of the control chip through a circuit, the vacuum pump is communicated and assembled with a test pipeline, and the test pipeline is provided with a test port for connecting a liquid shifter.
The pipeline pressure sensor is connected with the control input end of the control chip through a circuit, and the pipeline pressure sensor is correspondingly arranged on the test pipeline and used for detecting the pipeline tightness of the pipettor by means of the pipeline pressure sensor.
The storage module is connected with the control chip through a circuit so as to establish data intercommunication sharing between the storage module and the control chip, the storage module can store a preset standard pressure value threshold value or short-term storage part measurement data, and the control chip can call data information in the storage module and utilize the data information, so that more accurate analysis and comparison control of detection parameters is realized, and the detection accuracy is improved.
The timing module is connected with the control chip through a circuit, and is used for realizing timing functions including but not limited to measuring the starting time and measuring the remaining time by means of the timing module.
The display screen is connected with the control output end of the control chip through a circuit and used for displaying the air pressure value, the air density value, the air humidity value, the air temperature value, the pressure value, the measurement countdown, the pressure difference value and the measurement result data of the experimental environment in real time through the display screen. The pressure value shows a currently measured negative pressure value in the pipette pipeline; the measurement countdown is used for displaying the measurement residual time, and the negative pressure reaches-40 kPa during measurement to start timing; the pressure difference value shows the absolute value of the pressure difference before and after measurement; the measurements show failed or pass indications at the bottom of the display screen, identifying the last measurement.
Description of flow of detection of pipette adhesion:
pressing a menu key of a control panel button to select a measurement mode;
connecting a port of a test pipeline communicated with a vacuum pump with a pipettor to be tested, and then pressing a confirmation key to start measurement;
the control chip controls the vacuum pump to pump the liquid transfer pipe to negative pressure of-40 kPa;
the pipeline pressure sensor starts to measure until negative pressure of-40 kPa is reached, and meanwhile, the timing module starts to count down;
when the absolute value of the pressure difference before and after measurement is not more than 5kPa after the countdown is finished, the measurement is passed, and the tightness of the pipettor to be measured is qualified; otherwise, the measurement fails (failed), and the tightness of the liquid transfer device to be measured is not qualified;
and pressing a determination key on the measurement interface to perform measurement again.
As shown in fig. 2 to 4, the embodiment of the present invention further provides a device for integrating monitoring of an experimental environment and detection of pipette adhesion, which is used as a carrier for carrying the system integrating monitoring of an experimental environment and detection of pipette adhesion; the device comprises a shell 1, a first end cover 2, a support leg 3, a second end cover 4, a dispensing sealing ring 5, a fastening screw 6, a display screen 7 and an operation panel button 8; the first end cover 2 and the second end cover 4 are respectively buckled in a one-to-one correspondence manner and are fixedly connected to two side parts of the shell 1 through the fastening screws 6 to form an installation framework of the detection device; the first end cover 2 and the second end cover 4 are respectively and fixedly connected with support legs 3, so that the overall stability of the mounting structure is improved through the support legs 3; glue dispensing sealing rings 5 are arranged among the first end cover 2, the second end cover 4 and the shell 1, so that the overall sealing performance is effectively improved, ash and water are prevented from entering, the service life of accessories is prolonged, and meanwhile, the working noise is reduced; the display 7 and the manipulation panel buttons 8 are respectively mounted to the housing 1.
As a preferred aspect of this embodiment, the present invention further provides a self-test method for a device integrating an experimental environment monitoring and a pipette adhesion detection, including the steps of:
pressing a menu key in an operation panel button of a main interface of the shell 1, selecting self-checking at the menu key, and pressing a confirm key to enter a self-checking mode.
Under the self-checking mode, can show the current real-time pressure value in the test pipeline that links to each other with the vacuum pump, the enter key opens the vacuum pump, plugs up the test port of test pipeline, makes the interior negative pressure state that forms of test pipeline.
And (4) closing the vacuum pump in a negative pressure state, observing data change, and detecting whether the inside of the device leaks air.
Although the invention has been described in detail above with reference to a general description and specific examples, it will be apparent to one skilled in the art that modifications or improvements may be made thereto based on the invention. Accordingly, it is intended that all such modifications and alterations be included within the scope of this invention as defined in the appended claims.

Claims (10)

1. A system integrating environment monitoring and pipettor sealing performance detection is characterized by comprising a control chip, a power module, a control panel button, a storage module, an air parameter sensor, a vacuum pump and a pipeline pressure sensor;
the control chip is connected with the power module through a circuit;
the control panel button is connected with the control input end of the control chip through a circuit;
the air parameter sensor is connected with the control input end of the control chip through a circuit;
the vacuum pump is connected with the control output end of the control chip through a circuit, the vacuum pump is communicated and assembled with a test pipeline, and the test pipeline is provided with a test port for connecting the pipettor;
the pipeline pressure sensor is connected with the control input end of the control chip through a circuit, and the pipeline pressure sensor is correspondingly assembled on the test pipeline;
the storage module is connected with the control chip through a circuit, and data intercommunication sharing is established between the storage module and the control chip.
2. The system integrating environment monitoring and pipette seal detection according to claim 1, wherein,
the air parameter sensor comprises an air pressure sensor, an air density sensor, an air humidity sensor and an air temperature sensor;
the air pressure sensor, the air density sensor, the air humidity sensor and the air temperature sensor are respectively connected with the control input end of the control chip through circuits;
the air pressure value of air pressure sensor real-time supervision experiment environment air, the air density of air density sensor real-time supervision experiment environment air, the air humidity of air humidity sensor real-time supervision experiment environment air, the air temperature of air temperature sensor real-time supervision experiment environment air.
3. The system integrating environment monitoring and pipette seal detection of claim 1, further comprising a display screen;
the display screen is connected with the control output end of the control chip through a circuit;
the display screen displays the air pressure value, the air density value, the air humidity value, the air temperature value, the pressure value, the measurement countdown, the pressure difference value and the measurement result data of the experimental environment in real time.
4. The system integrating environment monitoring and pipette seal detection according to claim 3,
the pressure value is displayed as a currently measured negative pressure value within the pipette channel.
5. The system integrating environment monitoring and pipette seal detection according to claim 3,
and the measurement countdown is displayed as the measurement remaining time, and the negative pressure reaches-40 kPa during measurement to start timing.
6. The system integrating environment monitoring and pipette seal detection according to claim 3,
the pressure difference is displayed as an absolute value of the pressure difference before and after measurement;
and displaying failed or pass identification on the bottom of the display screen according to the measurement result, and identifying the latest measurement result.
7. The system integrating environmental monitoring and pipette seal detection of claim 3, further comprising a timing module;
the timing module is connected with the control chip through a circuit, and the timing module is used for timing measurement starting time and/or measurement remaining time.
8. A method for detecting pipette adhesion using the system for integrating environment monitoring and pipette adhesion detection according to claim 7, comprising the steps of:
description of procedure for detection of pipette adhesion:
pressing a menu key of a control panel button to select a measurement mode;
connecting a port of a test pipeline communicated with a vacuum pump with a pipettor to be tested, and then pressing a confirmation key to start measurement;
the control chip controls the vacuum pump to pump the liquid transfer pipe to negative pressure of-40 kPa;
the pipeline pressure sensor starts to measure until negative pressure of-40 kPa is reached, and meanwhile, the timing module starts to count down;
when the absolute value of the pressure difference before and after measurement is not more than 5kPa after the countdown is finished, the measurement is passed, and the tightness of the pipettor to be measured is qualified; otherwise, the measurement fails (failed), and the tightness of the liquid transfer device to be measured is not qualified;
and pressing a determination key on the measurement interface to perform measurement again.
9. A device carrying the system for integrating environmental monitoring and pipette adhesion detection according to claim 7, comprising:
the device comprises a shell, a first end cover, a second end cover, a fastening screw, a display screen and a control panel button;
the first end cover and the second end cover are correspondingly buckled one by one respectively and are fixedly connected to two side parts of the shell through the fastening screws;
the first end cover and the second end cover are fixedly connected with support legs respectively;
dispensing sealing rings are arranged among the first end cover, the second end cover and the shell;
the display screen and the control panel buttons are respectively assembled on the shell.
10. A method of self-testing of the apparatus of claim 9, comprising the steps of:
pressing a menu key in a control panel button of a shell main interface, selecting self-checking at the menu key, and pressing a confirm key to enter a self-checking mode;
in the self-checking mode, displaying a real-time pressure value in a test pipeline connected with the vacuum pump at present, opening the vacuum pump by a confirmation key, and blocking a test port of the test pipeline to enable a negative pressure state to be formed in the test pipeline;
and (4) closing the vacuum pump in a negative pressure state, observing data change, and detecting whether the inside of the device leaks air.
CN202211325462.1A 2022-10-27 2022-10-27 System, device and method integrating environment monitoring and pipettor tightness detection Pending CN115655365A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202211325462.1A CN115655365A (en) 2022-10-27 2022-10-27 System, device and method integrating environment monitoring and pipettor tightness detection

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202211325462.1A CN115655365A (en) 2022-10-27 2022-10-27 System, device and method integrating environment monitoring and pipettor tightness detection

Publications (1)

Publication Number Publication Date
CN115655365A true CN115655365A (en) 2023-01-31

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN202211325462.1A Pending CN115655365A (en) 2022-10-27 2022-10-27 System, device and method integrating environment monitoring and pipettor tightness detection

Country Status (1)

Country Link
CN (1) CN115655365A (en)

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