CN115650220B - Molecular signal transmission capacity enhancing method - Google Patents
Molecular signal transmission capacity enhancing method Download PDFInfo
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- CN115650220B CN115650220B CN202211308996.3A CN202211308996A CN115650220B CN 115650220 B CN115650220 B CN 115650220B CN 202211308996 A CN202211308996 A CN 202211308996A CN 115650220 B CN115650220 B CN 115650220B
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- 230000008054 signal transmission Effects 0.000 title claims abstract description 51
- 238000000034 method Methods 0.000 title claims abstract description 29
- 230000002708 enhancing effect Effects 0.000 title claims abstract description 10
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims abstract description 101
- 229910021389 graphene Inorganic materials 0.000 claims abstract description 93
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 73
- 238000005381 potential energy Methods 0.000 claims abstract description 14
- 238000009826 distribution Methods 0.000 claims abstract description 11
- 239000007864 aqueous solution Substances 0.000 claims abstract description 10
- 238000012986 modification Methods 0.000 claims abstract description 9
- 230000004048 modification Effects 0.000 claims abstract description 9
- 230000003993 interaction Effects 0.000 claims abstract description 8
- 230000011664 signaling Effects 0.000 claims description 8
- 230000000694 effects Effects 0.000 claims description 7
- 125000000524 functional group Chemical group 0.000 claims description 5
- 230000007547 defect Effects 0.000 claims description 4
- 238000001338 self-assembly Methods 0.000 claims description 4
- 238000007385 chemical modification Methods 0.000 claims description 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims description 3
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims description 3
- 125000004430 oxygen atom Chemical group O* 0.000 claims description 3
- 230000001590 oxidative effect Effects 0.000 claims description 2
- 230000005540 biological transmission Effects 0.000 abstract description 8
- 108091006146 Channels Proteins 0.000 description 101
- 239000002041 carbon nanotube Substances 0.000 description 6
- 229910021393 carbon nanotube Inorganic materials 0.000 description 6
- 238000010586 diagram Methods 0.000 description 3
- 102000010637 Aquaporins Human genes 0.000 description 1
- 108010063290 Aquaporins Proteins 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 238000010612 desalination reaction Methods 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 230000017525 heat dissipation Effects 0.000 description 1
- 229910052739 hydrogen Inorganic materials 0.000 description 1
- 239000001257 hydrogen Substances 0.000 description 1
- 230000001965 increasing effect Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 239000013535 sea water Substances 0.000 description 1
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Abstract
The application discloses a method for enhancing molecular signal transmission capacity, which relates to the technical field of signal transmission, and comprises the following steps: constructing a polygonal graphene channel, and placing the polygonal graphene channel in an aqueous solution to fill the inside of the channel with water molecules; the water molecules are influenced by interaction potential energy distribution of water at the cross section of the channel and the inner wall of the channel, are fixed at each folding angle of the polygonal graphene channel, and transmit molecular signals along the axial direction of the channel, and each folding angle correspondingly forms a signal transmission channel; and carrying out surface charge modification on the polygonal graphene channels, and changing the dipole directions of water molecules of all the signal transmission channels so as to enhance the molecular signal intensity transmitted by each signal transmission channel. The method is based on the polygonal structure shape of the graphene channels, so that one graphene channel is provided with a plurality of transmission links, and the transmission capacity of molecular level signals is improved.
Description
Technical Field
The application relates to the technical field of signal transmission, in particular to a method for enhancing the transmission capacity of a molecular signal.
Background
Given the large number of molecular level signaling in organisms and the important role these have in the formation of organisms, molecular-based signaling and enhancement studies are also paramount in the trend of today's smaller and smaller electronic device sizes. Because of the ultra-low coefficient of friction with water and the ultra-high fairness of water structure, the transportation and filtration of water in the channels of graphite structure has been widely used for chip heat dissipation and sea water desalination, and water is considered to realize ultra-long distance signal transmission almost instantaneously, which has attracted extensive research interests. However, the conventional carbon nanotube channels often exist in a circular form, so that the distribution of water molecules at the cross section is very disordered, the characteristic of identical particles is presented, and the circular carbon nanotube has only one water molecule chain for signal transmission, so that the transmission of molecular level signals is limited, and the dipole direction is continuously changed due to the rotation of the water molecules, so that the timeliness and accuracy of signal transmission are greatly reduced, and the practical application value is limited.
Disclosure of Invention
The inventor provides a molecular signal transmission capability enhancement method aiming at the problems and the technical requirements, and as the cross section of the polygonal graphene channel is not as full as a circle, and according to the difference of potential energy distribution of interaction between water and the inner wall of the channel at the cross section of the polygonal graphene channel, water molecules tend to be distributed at the lower potential energy, so that the interaction of water molecules at different positions in the same cross section is reduced, and the transmission capability of molecular signals is enhanced.
The technical scheme of the application is as follows:
a method for enhancing the signaling capacity of a molecule, comprising the steps of:
constructing a polygonal graphene channel, and placing the polygonal graphene channel in an aqueous solution to fill the inside of the channel with water molecules; the water molecules are influenced by interaction potential energy distribution of water at the cross section of the channel and the inner wall of the channel, are fixed at each folded corner of the polygonal graphene channel, and transmit molecular signals along the axial direction of the channel, and each folded corner correspondingly forms a signal transmission channel along the axial direction;
and carrying out surface charge modification on the polygonal graphene channels, and changing the dipole directions of water molecules of all the signal transmission channels so as to enhance the intensity of molecular signals transmitted by the signal transmission channels.
The further technical scheme is that the polygonal graphene channel is constructed, and the polygonal graphene channel comprises:
oxidizing the surface of the monolithic graphene by a chemical modification method to form hydroxyl, oxygen atom or hydrogen atom;
and (3) placing the plurality of single graphene oxide sheets in an aqueous solution for assembly, or placing the single graphene oxide sheets in the aqueous solution for self-assembly to obtain the polygonal graphene channel.
The further technical scheme is that the polygonal graphene channel is subjected to surface charge modification to change the dipole direction of water molecules of all signal transmission channels, and the method comprises the following steps:
the method comprises the steps that defects are manufactured on the surface of a polygonal graphene channel, or a single functional group is introduced, so that the inner wall of the polygonal graphene channel is provided with negative charges; along with the introduction of negative charges, the dipole direction of water molecules with the smallest distance from the negative charges changes, so that the change of the dipole direction of the water molecules in each signal transmission channel is influenced, and finally, the dipole direction of the water molecules in each signal transmission channel is fixed.
The method further comprises the following steps:
the position and/or the intensity of negative charges on the inner wall surface of the polygonal graphene channel are adjusted, so that the polygonal graphene channel has the function of transmitting different molecular signals.
The method further comprises the following steps:
the molecular signal is described by the dipole direction of the water molecule as a whole, comprising:
the included angle between the water molecule dipole direction of any signal transmission channel and the axis of the polygonal graphene channel is as follows:
wherein ,is the dipole direction of the ith water molecule of the signal transmission channel,/->Is the axial direction of the polygonal graphene channel;
the average dipole angle of the water molecule ensemble under the signal transfer channel is:
wherein N (t) is the number of water molecules in the signal transmission channel at the moment t;
the transmitted molecular signals are distinguished by taking the average dipole angle of each signal transmission channel.
The cross section of the polygonal graphene channel comprises a triangle, a quadrangle, a pentagon and a hexagon, and the width of the polygonal graphene channel is determined according to the inscribed circle radius of the channel.
According to the technical scheme, the smaller the angle of the polygonal graphene channel is, the smaller the potential energy of the angle area is, so that the better the fixing effect on water molecules is.
According to the technical scheme, the intensities of molecular signals transmitted by graphene channels with different cross-sectional shapes are different.
The beneficial technical effects of the application are as follows:
on the one hand, the method utilizes the potential energy distribution difference of the water and the polygonal graphene channels, compared with the single-chain transfer channels of the circular carbon nano tube, the radial molecular signal transfer interference effect is weakened due to the constraint effect of the folding angle, the axial molecular signal transfer is enhanced, and a plurality of signal transfer channels are used for transferring molecular signals, each signal transfer channel is hardly affected, and the transfer capacity of molecular level signals is greatly enhanced. On the other hand, through carrying out the surface charge modification to polygonal graphene channel for the whole dipole direction of hydrone of all signal transmission channels is fixed, compares in circular carbon nanotube, and the signal transmission channel that dipole direction is fixed can strengthen the molecular signal intensity of transmission, makes it reduce the noise of its transportation signal when keeping high efficiency.
Drawings
FIG. 1 is a schematic flow chart of the method provided by the application.
Fig. 2 is a schematic structural diagram of a polygonal graphene channel provided by the present application, in which: (a) is a triangular graphene channel structure, (b) is a quadrilateral graphene channel structure, (c) is a pentagonal graphene channel structure, and (d) is a hexagonal graphene channel structure.
Fig. 3 is a graph of interaction potential energy distribution of polygonal graphene channels and water molecules, provided by the application, wherein: (a) corresponds to a triangular graphene channel structure, (b) corresponds to a quadrilateral graphene channel structure, (c) corresponds to a pentagonal graphene channel structure, and (d) corresponds to a hexagonal graphene channel structure.
Fig. 4 is a schematic diagram of signal transmission of a pentagonal graphene channel provided by the application.
Detailed Description
The following describes the embodiments of the present application further with reference to the drawings.
As shown in fig. 1, the present application provides a method for enhancing the signaling capacity of a molecule, comprising the following steps:
s1: constructing a polygonal graphene channel, specifically including:
s11: functional groups are added on the surface of the monolithic graphene through a chemical modification method, namely, the surface of the monolithic graphene is oxidized, and hydroxyl, oxygen atoms or hydrogen atoms are formed at specific positions on the surface. The specific positions are selected according to an assembly mode, for example, an assembly mode is adopted, and two sides of the single graphene are the specific positions; if a self-assembly mode is adopted, the crease of the polygon formed by the single graphene is the specific position of the polygon.
S12: and (3) placing the plurality of single graphene oxide sheets in an aqueous solution for assembly, or placing the single graphene oxide sheets in the aqueous solution for self-assembly to obtain the polygonal graphene channel.
The monolithic graphene has the characteristic of long strips, the length is about 0.1-1 micron, and the width is about 5 nanometers. As shown in fig. 2, the cross-sectional shape of the polygonal graphene channel includes triangle, quadrangle, pentagon and hexagon, and the width of the polygonal graphene channel is determined according to the channel inscribed circle radius R.
S2: and (3) placing the polygonal graphene channel prepared in the step (S1) in an aqueous solution to fill the inside of the channel with water molecules.
The interaction potential energy distribution of the graphene channels with different cross-sectional shapes and water molecules is shown in fig. 3 (a) - (d), the water molecules are influenced by the interaction potential energy distribution of the water at the cross section of the channel and the inner wall of the channel, are fixed at each folded corner of the polygonal graphene channel (the folded corner potential energy is small), and transmit molecular signals along the axial direction of the channel. Namely, each folded angle forms a signal transmission channel correspondingly along the axial direction, so that the mutual influence of water molecules at different positions in the same cross section is reduced, and the signal transmission capacity of molecular signals can be enhanced by a plurality of signal transmission channels.
And the smaller the angle of the polygonal graphene channel is, the smaller the potential energy of the angle area is, so that the better the fixing effect on water molecules is. For example, triangular graphene channels have better signal transmission effects than the rest of polygonal graphene channels.
S3: carrying out surface charge modification on polygonal graphene channels to change the dipole direction of water molecules of all signal transmission channels, wherein the method specifically comprises the following steps:
the inner wall of the polygonal graphene channel is provided with a negative charge by manufacturing defects on the surface of the polygonal graphene channel or introducing a single functional group. Referring to a signal transmission schematic diagram of the pentagon graphene channel shown in fig. 4 after negative charges are introduced, the dipole direction of water molecules with the smallest distance from the negative charges is changed, namely, the dipole direction of single water molecules is changed, so that the change of the dipole directions of the water molecules in each signal transmission channel is influenced, the dipole directions of the water molecules in each signal transmission channel are finally fixed, the molecular signal intensity of graphene channel transportation under the shape is enhanced, and the graphene channels with different cross section shapes can meet the transportation with different signal intensities due to the difference of the signal transmission channels and the different intensities of the transferred molecular signals.
S4: the position and/or the intensity of negative charges on the inner wall surface of the polygonal graphene channel are adjusted, so that the polygonal graphene channel has the function of transmitting different molecular signals.
Specifically, each time the placement position of the negative charge is adjusted, so that the water molecules with the smallest distance from the negative charge change the dipole orientation at different angles each time, different molecular signals are transmitted, corresponding to the description of S5. And/or, each time the magnitude of the charges of the negative charges is adjusted, the degree of changing the dipole direction of the water molecules with the smallest distance from the negative charges is different, the stability of the dipole of the water molecules is influenced by the strength of the negative charges, and the transmitted molecular signals are different when the stability is different.
S5: the molecular signal is described by the dipole direction of the water molecule as a whole, comprising:
the included angle between the water molecule dipole direction of any signal transmission channel and the axis of the polygonal graphene channel is as follows:
wherein ,is the dipole direction of the ith water molecule of the signal transmission channel,/->Is the axial orientation of the polygonal graphene channels.
The average dipole angle of the water molecule ensemble under the signal transfer channel is:
wherein N (t) is the number of water molecules in the signal transmission channel at the moment t.
The transmitted molecular signals are distinguished by taking the average dipole angle of each signal transmission channel.
In this embodiment, on the one hand, the method simply changes the original graphene structure, and different polygonal graphene channels are manufactured by controlling the distribution of the functional groups. Under the condition that the cross sections are different, the potential energy increasing effect of the polygonal channel folding angle part on which the water molecules are subjected is different, the folding angle is reduced by changing the shape of the polygonal channel, the water molecules can be more effectively gathered at the folding angle part, the restraint is stronger, the water molecules are less susceptible to the influence of the water molecules positioned in the same cross section, and more changes are made in the axial direction, so that the signal enhancing effect is generated. And when the round carbon nano tube conveys signals, only one water molecule chain conveys signals, so that the conveyed signals are few, and the dipole direction is continuously changed due to the rotation of water molecules, so that the timeliness and the accuracy of signal transmission are greatly reduced, and the polygonal graphene channel improves the defect through surface charge modification, enhances the transmission of molecular signals, and reduces the noise of the conveyed signals while keeping high efficiency.
On the other hand, by modifying the surface charge of the polygonal graphene channel, as the water molecule clusters exist in a single-chain or layered structure in the channel with a particularly small pipe diameter, the dipole direction of the water molecules in the hydrogen bond network in the whole graphene channel can be effectively and quickly changed in a long channel by changing the dipole direction of single water molecules, and the dipole distribution direction of the water molecules can be effectively changed along with the change of the wall charges like the signal binary signal transmission in a computer. The specific signal transmission channels formed by the application can enhance the intensity of transmitted molecular signals so as to meet the transmission of molecular signals with different intensities, compared with the continuous change of the water molecule dipole direction brought by the circular carbon nano tube.
The above is only a preferred embodiment of the present application, and the present application is not limited to the above examples. It is to be understood that other modifications and variations which may be directly derived or contemplated by those skilled in the art without departing from the spirit and concepts of the present application are deemed to be included within the scope of the present application.
Claims (6)
1. A method of enhancing the signaling capacity of a molecule, the method comprising:
constructing a polygonal graphene channel, and placing the polygonal graphene channel in an aqueous solution to fill the inside of the channel with water molecules; the water molecules are influenced by interaction potential energy distribution of water at the cross section of the channel and the inner wall of the channel, are fixed at each folded corner of the polygonal graphene channel, and transmit molecular signals along the axial direction of the channel, and each folded corner correspondingly forms a signal transmission channel along the axial direction;
carrying out surface charge modification on the polygonal graphene channels, and changing the dipole directions of water molecules of all the signal transmission channels so as to enhance the strength of molecular signals transmitted by the signal transmission channels;
wherein, the constructing polygonal graphene channels includes:
oxidizing the surface of the monolithic graphene by a chemical modification method to form hydroxyl, oxygen atom or hydrogen atom; placing a plurality of single graphene oxide sheets in an aqueous solution for assembly, or placing the single graphene oxide sheets in the aqueous solution for self-assembly to obtain a polygonal graphene channel;
the surface charge modification is performed on the polygonal graphene channels, so that the dipole directions of water molecules of all the signal transmission channels are changed, and the method comprises the following steps:
the method comprises the steps that defects are manufactured on the surface of a polygonal graphene channel, or a single functional group is introduced, so that the inner wall of the polygonal graphene channel is provided with negative charges; along with the introduction of negative charges, the dipole direction of water molecules with the smallest distance from the negative charges changes, so that the change of the dipole direction of the water molecules in each signal transmission channel is influenced, and finally, the dipole direction of the water molecules in each signal transmission channel is fixed.
2. The method of claim 1, further comprising:
and adjusting the position and/or the strength of negative charges on the inner wall surface of the polygonal graphene channel to realize that the polygonal graphene channel has the function of transmitting different molecular signals.
3. The method of enhancing molecular signaling capacity according to claim 1 or 2, wherein the method further comprises:
the molecular signal is described by the dipole direction of the water molecule as a whole, comprising:
the included angle between the water molecule dipole direction of any signal transmission channel and the axis of the polygonal graphene channel is as follows:
；
wherein ,is the first signal transmission channeliDipole direction of individual water molecules->Is the axial direction of the polygonal graphene channel;
the average dipole angle of the water molecule ensemble under the signal transfer channel is:
；
wherein ,N(t) Is thattThe number of water molecules in the time signal transmission channel;
the transmitted molecular signals are distinguished by taking the average dipole angle of each signal transmission channel.
4. The molecular signaling enhancement method of claim 1, wherein the cross-sectional shape of the polygonal graphene channels comprises triangles, quadrilaterals, pentagons, and hexagons, and the width of the polygonal graphene channels is determined according to the channel inscribed circle radius.
5. The method for enhancing molecular signaling ability according to claim 4, wherein the smaller the angle of the polygonal graphene channel is, the smaller the potential energy of the angle-folded region is, so that the better the fixing effect on water molecules is.
6. The method of claim 4, wherein the intensities of the molecular signals transmitted by the graphene channels of different cross-sectional shapes are different.
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| US9102540B2 (en) * | 2011-07-31 | 2015-08-11 | International Business Machines Corporation | Graphene nanomesh based charge sensor |
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| CN108548807A (en) * | 2018-03-15 | 2018-09-18 | 国家纳米科学中心 | Graphene phasmon device and preparation method thereof for enhanced highpass filtering signal |
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