CN115631806A - Method for rapidly evaluating wear performance of toothpaste, grading method and formula design method - Google Patents
Method for rapidly evaluating wear performance of toothpaste, grading method and formula design method Download PDFInfo
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- 229940034610 toothpaste Drugs 0.000 title claims abstract description 182
- 238000000034 method Methods 0.000 title claims abstract description 44
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- 238000004140 cleaning Methods 0.000 claims abstract description 48
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 98
- 239000000377 silicon dioxide Substances 0.000 claims description 49
- 238000005299 abrasion Methods 0.000 claims description 34
- 238000012360 testing method Methods 0.000 claims description 32
- 238000001514 detection method Methods 0.000 claims description 16
- 238000013210 evaluation model Methods 0.000 claims description 15
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- 239000003082 abrasive agent Substances 0.000 description 7
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- 210000003298 dental enamel Anatomy 0.000 description 5
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- 230000008569 process Effects 0.000 description 5
- 238000011160 research Methods 0.000 description 5
- 230000036346 tooth eruption Effects 0.000 description 5
- 230000032724 odontogenesis Effects 0.000 description 4
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 3
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- 229940095688 toothpaste product Drugs 0.000 description 2
- FTLYMKDSHNWQKD-UHFFFAOYSA-N (2,4,5-trichlorophenyl)boronic acid Chemical class OB(O)C1=CC(Cl)=C(Cl)C=C1Cl FTLYMKDSHNWQKD-UHFFFAOYSA-N 0.000 description 1
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- 208000002697 Tooth Abrasion Diseases 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
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- 230000035479 physiological effects, processes and functions Effects 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
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- WXMKPNITSTVMEF-UHFFFAOYSA-M sodium benzoate Chemical compound [Na+].[O-]C(=O)C1=CC=CC=C1 WXMKPNITSTVMEF-UHFFFAOYSA-M 0.000 description 1
- 235000010234 sodium benzoate Nutrition 0.000 description 1
- 239000004299 sodium benzoate Substances 0.000 description 1
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- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
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- 239000000230 xanthan gum Substances 0.000 description 1
- 229920001285 xanthan gum Polymers 0.000 description 1
- 229940082509 xanthan gum Drugs 0.000 description 1
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Abstract
The invention relates to a method for evaluating the cleaning power and the wear performance of toothpaste for children, in particular to a mathematical model for evaluating the wear performance of the toothpaste for children. The toothpaste provided by the invention can be used for rapidly evaluating the wear performance of the toothpaste for children and rapidly and quantitatively researching the cleaning power and the wear performance of the toothpaste for children of different ages, so that the tooth cleaning effect and the use safety of the toothpaste for children are ensured.
Description
Technical Field
The invention relates to a method for evaluating wear performance of silicon dioxide, in particular to a method for evaluating wear value of toothpaste for children, a grading method and a formula design method.
Background
The abrasive is a basic component for increasing the friction between toothpaste and teeth and playing a role in cleaning. The function of toothpaste is important during the brushing process, and the friction of the toothpaste is one of important factors for mechanically removing tooth stains. In order to achieve good cleaning without damaging the teeth and gums, consideration should be given to both cleaning and safety. The indicators in the oral care industry that evaluate toothpaste cleaning and abrasion performance are biofilm cleaning rate PCR and relative dentin abrasion RDA. The toothpaste has high and low friction performance, which is closely related to the shape, size, hardness and content of the used abrasive. However, the toothpaste friction is not always proportional to the cleaning effect, and when the friction exceeds a critical value, the cleaning effect cannot be further improved, and the tooth abrasion may be caused. Therefore, toothpaste should be abrasive in that it can remove plaque and stains without damaging dentin. The detected wear value of the whitening commercial toothpaste is mostly between 50 and 150, and related researches suggest that the necessary cleaning performance cannot be achieved when the friction of an abrasive in the toothpaste is too low (RDA < 50).
The PCR value of common friction type silicon dioxide in the current market is 80-95, and the RDA value is 80-110; the PCR value of the medium friction type silica is 90-100, and the RDA value is 130-180; the PCR value of the high-efficiency clean type silicon dioxide is 95-110, and the RDA value is 150-220. It can be seen that increasing the RDA value also increases the PCR value accordingly, but RDA increase is upper-limited. At present, the silica for QB2346 toothpaste and the GB8372 national standard do not have the requirement of the silica and the toothpaste on the abrasion performance index of teeth, and do not aim at explaining the use requirements of different groups. The american dental association ADA requires a toothpaste RDA with an upper limit of 250, but no indication is given as to the applicability of a toothpaste RDA for children. As for the toothpaste for children, a toothpaste abrasion performance evaluation standard is not established, and all industry standardization organizations should timely perfect the RDA standard suitable for the toothpaste for children.
Generally, when children are 2 and half years old, the primary teeth are all level, but the teeth are not calcified enough, and caries is easy to cause. Deciduous teeth are chewing organs of children, can not only chew foods, but also reflectively stimulate the increase of salivary secretion and are helpful for digestion and absorption of the foods. Around age 6, permanent teeth begin to erupt, and there are both deciduous teeth and permanent teeth, which are the main growth and development stages of the jaw and dental arch of children and the key stage for establishing the jaw of the permanent teeth. The abrasive used by the toothpaste for children is soft and soft, and the repeated friction during tooth brushing does not harm the surfaces of young teeth of children. The silicon dioxide is a mild and neutral soft abrasive, has proper friction, can achieve the effect of cleaning teeth of children without damaging the teeth of the children, has the characteristics of stable physical and chemical properties, good compatibility with a toothpaste system, capability of being used for preparing transparent toothpaste, and the like, and is widely applied to the toothpaste for the children at present. Related research data and data are not found for the toothpaste suitable for children used in different tooth development and growth stages. Therefore, the cleaning performance and abrasiveness of toothpaste abrasives, especially children's toothpaste, should be intensively studied.
The relative dentinal abrasion is used for testing the safety limit of toothpaste, the abrasion performance of a toothpaste test sample is currently and internationally tested mainly according to an ISO standard radioactive tracer method (ISO 11609:2010 (E) appendix A) and a surface profile method (ISO 11609:2010 (E) appendix B), a bovine tooth sample is used as an in-vitro experimental material, and a tooth sample is repeatedly brushed and ground by using a tooth brushing machine. The two methods are complicated in process and have great limitation on experimental equipment, so that the test period is long, the cost is high, and the radioactive tracing method is only used for authoritative detection of American Indiana university. GB/T35832 standard stipulates the detection method of toothpaste friction value Ra, through the size of the toothpaste friction value Ra of test, can direct quick evaluation judge toothpaste wear performance's level. Patent CN 104390873A "toothpaste abrasiveness detection method" discloses a detection method of a toothpaste friction value Ra, and fits the correlation between the friction value Ra and a relative dentin abrasion RDA value of 7 types of adult toothpaste, and the two have a good linear relationship. However, for the toothpaste for children with a significantly low wear value, there is no relevant research data, and the tooth development degrees of children of different ages are different, and the wear performance levels of the toothpaste used should be different. At present, no evaluation method for the wear performance of toothpaste for children of different ages exists, and the RDA value test period is long and the cost is high, so that the development period of toothpaste for children is too long.
Disclosure of Invention
In order to solve the technical problems, the invention relates to a method for evaluating the cleaning power and the abrasion performance of a silicon dioxide composition for children toothpaste, which comprises the steps of using different types and different amounts of silicon dioxide abrasive materials to combine to achieve different levels of cleaning power and abrasion performance, combining the oral development characteristics of children of different ages and the safety threshold value of RDA, designing and establishing different cleaning power and abrasion ranges, and providing evaluation grades of the cleaning effect and the abrasion performance of the children toothpaste of different ages. Further, the linear correlation of the Ra value and the RDA value of the toothpaste for children is systematically researched, a corresponding mathematical evaluation model of the toothpaste abrasion performance is established, and the quantitative evaluation of the abrasion performance of the toothpaste for children in different ages is quickly realized.
A method for establishing a toothpaste abrasion performance rapid evaluation model is characterized by comprising the following steps:
step 1: screening the types of the silica which is suitable for the transparent toothpaste for children and has proper friction, applying the silica with different types and different dosages to the basic formula of the transparent toothpaste for children, and keeping the dosages of other formula components unchanged.
Step 2: preparing a series of toothpaste samples according to the step 1, respectively testing the Ra value of the toothpaste by adopting a GB/T35832 toothpaste friction value Ra detection method, testing the film cleaning power PCR value of the toothpaste by adopting a toothpaste exogenous color spot removal testing method, and simultaneously testing the RDA value of each toothpaste by adopting an ISO11609 radioactive tracer method.
And 3, step 3: performing data fitting analysis on the RDA value and the Ra value obtained by testing each toothpaste sample, and establishing a toothpaste wear performance evaluation model for children: RDA =107.2Ra +11.553, and the mathematical model represents a functional relationship between the toothpaste abrasion value and the friction value.
And 4, step 4: and (5) rapidly evaluating the wear performance of the toothpaste for children according to the evaluation model.
By means of the establishment of the mathematical model, the toothpaste formula development design and the toothpaste abrasion performance level prediction can be theoretically guided.
Furthermore, through data statistical analysis of RDA and PCR values acquired by children toothpaste with different abrasives, 3 grades of wear performance of the children toothpaste are divided into 30-50 RDA, 50-70 RDA and 70-90 RDA, and by combining development characteristics of different age groups of children teeth, such as deciduous teeth stage, early mixed dentition and late mixed dentition stage, the cleaning power and the use safety of the children toothpaste at different age groups are guaranteed.
A children toothpaste RDA grading method is characterized by comprising the following steps:
step 1: screening the types of the silica which is suitable for the transparent toothpaste for children and has proper friction, applying the silica with different types and different dosages to the basic formula of the transparent toothpaste for children, and keeping the dosages of other formula components unchanged.
And 2, step: preparing a series of toothpaste samples according to the step 1, and testing the Ra value of the toothpaste by respectively adopting a GB/T35832 toothpaste friction value Ra detection method and testing the cleaning power PCR value of the toothpaste by adopting a biomembrane cleaning rate PCR detection method.
And 3, step 3: performing data fitting analysis on the RDA value and the Ra value obtained by testing each toothpaste sample in the step 2, and establishing a toothpaste wear performance evaluation model for children: RDA =107.2Ra +11.553, linear correlation coefficient R 2 Is 0.9176.
And 4, step 4: according to the children toothpaste wear performance evaluation model, 3 grades of the children toothpaste wear performance are divided into 30-50 RDAs, 50-70 RDAs and 70-90 RDAs respectively.
A design method of a children toothpaste formula is characterized by comprising the following steps:
step 1: screening the types of the silica which is suitable for the transparent toothpaste for children and has proper friction, applying the silica with different types and different dosages to the basic formula of the transparent toothpaste for children, and keeping the dosages of other formula components unchanged.
Step 2: preparing a series of toothpaste samples according to the step 1, and respectively testing the Ra value of the toothpaste by adopting a GB/T35832 toothpaste friction value Ra detection method and testing the cleaning power PCR value of the toothpaste by adopting a biomembrane cleaning rate PCR detection method.
And step 3: calculating the Ra value obtained by testing each toothpaste sample in the step 2 by adopting a toothpaste wear performance evaluation model for children to obtain the RDA value of each toothpaste sample: RDA =107.2Ra +11.553, linear correlation coefficient R 2 Is 0.9176.
And 4, step 4: and (3) obtaining the RDA value of each toothpaste sample according to the step (3), judging whether the RDA value meets the design requirement to obtain a toothpaste formula, if not, changing different abrasive proportions and repeating the steps (1-3) until the RDA value meets the design requirement.
The invention has the following beneficial technical effects:
1. according to the method for evaluating the wear performance of the toothpaste for children, disclosed by the invention, through the application of a large number of basic formulas of different types and dosages of silica with appropriate friction force for the toothpaste, and a fitting equation between the friction value Ra of the toothpaste and the wear value RDA, the RDA value of the corresponding toothpaste can be quickly obtained only by testing the friction value Ra of the toothpaste, and the method is used for judging the wear performance and the cleaning performance level of a toothpaste product.
2. The method for establishing the toothpaste wear performance evaluation model is beneficial to the systematic research on the wear performance and the cleaning power of the toothpaste for children, can realize the formula of the toothpaste for children with different wear value ranges by using a linear fitting equation of the toothpaste wear performance, and is quick, simple, convenient, time-saving and labor-saving.
3. The toothpaste abrasion performance and cleaning force grading technology provided by the invention is used for carrying out data statistics analysis on the RDA and PCR values obtained by the toothpaste for children with different abrasive materials, provides 3 grades of the toothpaste abrasion performance of the toothpaste for children, and respectively comprises 30-50 RDA, 50-70 RDA and 70-90 RDA, and guarantees the cleaning force and the use safety of the toothpaste for children at different ages by combining the development characteristics of the teeth of children at different ages, such as deciduous teeth stage, early mixed dentition stage and late mixed dentition stage.
4. According to the design method of the children toothpaste formula, 3 grades of the wear performance of the children toothpaste are divided into 30-50 RDA, 50-70 RDA and 70-90 RDA, the development characteristics of different age groups of the teeth of children such as the deciduous teeth stage, the early mixed dentition stage and the late mixed dentition stage are combined, the test result is quickly obtained through a toothpaste wear performance linear fitting equation, research and development personnel can quickly adjust the formula ratio according to the result, and the research and development period is shortened.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be obtained by a person skilled in the art without inventive step based on the embodiments of the present invention, are within the scope of protection of the present invention.
The growth and development are a continuously changing process, children in different age stages are in different dentition periods, and have respective characteristics in physiology and psychology, so that corresponding oral health measures are necessary for each age stage. The teeth in children are mainly deciduous teeth and young permanent teeth, and mechanical cleaning is the most effective method for removing dental plaque and cleaning teeth. Compared with permanent teeth, deciduous teeth have obvious differences in anatomical morphology, tissue structure, mineralization degree, environment and the like. As mentioned previously, increasing the RDA value also correspondingly increases the PCR value, but RDA boosting is upper bounded. The correlation between the friction value Ra of the adult toothpaste and the relative dentin abrasion RDA value has a good linear relation, but the cleaning power and the abrasion performance of the toothpaste for children with different growth characteristics of children teeth in different age groups cannot be evaluated in the prior art due to the mild soft abrasive silicon dioxide used by the toothpaste, so that the development and development cycle of the toothpaste suitable for all age groups is too long.
The invention relates to a method for evaluating the cleaning power and the abrasion performance of a silica composition for children toothpaste.
Example 1: as shown in Table 1, 5 friction type silicas were selected respectively in the base formula of transparent toothpaste for children, the mass percentage of each friction type silica was increased sequentially, and the mass percentage of the corresponding thickening type silica was decreased sequentially.
The paste prepared according to the embodiment is tested for the Ra value by the GB/T35832 toothpaste friction value Ra detection method, the PCR value by the biomembrane cleaning rate evaluation method and the RDA value by the ISO11609 radioactive tracer method, and the experimental results are as follows:
| scheme 1 | Scheme 2 | Scheme 3 | Scheme 4 | Scheme 5 | Scheme 6 | Scheme 7 | Scheme 8 | Scheme 9 | Scheme 10 | |
| RDA value | 43.87 | 63.03 | 77.19 | 47.23 | 68.04 | 87.74 | 54.60 | 60.53 | 30.70 | 41.94 |
| PCR value | 60.03 | 90.95 | 115.89 | 71.94 | 98.67 | 125.82 | 70.05 | 104.84 | 49.86 | 50.71 |
| Ra value | 0.371 | 0.456 | 0.599 | 0.375 | 0.566 | 0.691 | 0.313 | 0.422 | 0.214 | 0.299 |
Performing linear fitting analysis on the toothpaste friction value Ra and the relative dentin abrasion value RDA by adopting statistical software SPSS to obtain a linear relation between the two values: RDA =107.2Ra +11.553, correlation coefficient R 2 Was 0.9176. The linear fit relationship is independent of both the type and the content of the silica employed.
Example 2 application of model for rapid evaluation of toothpaste abrasion Performance
Designing a toothpaste formula which comprises the following components:
the percentage is the percentage of each component in the total weight of the formula.
The toothpaste wear performance quick evaluation model obtained according to example 1: RDA =107.2Ra +11.553, and the theoretical value of RDA of the toothpaste is calculated to be 56.79 by testing the Ra value of the toothpaste to be 0.452, the actual RDA value of the toothpaste to be tested is 60.01, and the theoretical calculation is close to the actual test data.
EXAMPLE 3 model application for Rapid toothpaste wear Performance evaluation
If a developer wants to design a children toothpaste with an RDA of 90, and the added silica abrasive in the formula is only 1 type, the abrasion performance evaluation mathematical model of the toothpaste obtained in example 1 is used for calculation, and the corresponding friction value Ra of the children toothpaste is 0.73. Meanwhile, fitting the linear relation between the formula dosage of the silicon dioxide model 1 and the Ra value: ra =1.9771X +0.2704, and the correlation coefficient is 0.9754. The amount of silica added can be directly calculated by the fitting formula. Aiming at other types of silicon dioxide, the specific dosage of the silicon dioxide can be determined by measuring and calculating the Ra value of the type of silicon dioxide toothpaste with different contents, the development and prospective design is realized, and not only can a better tooth cleaning effect be achieved, but also the teeth can not be damaged.
| Scheme 1 | Scheme 11 | Scheme 2 | Scheme 3 | Scheme 12 | |
| Sorbitol | 60 | 60 | 60 | 60 | 60 |
| PEG－8 | 2 | 2 | 2 | 2 | 2 |
| Glycerol | 2 | 2 | 2 | 2 | 2 |
| Sodium dodecyl sulfate | 1 | 1 | 1 | 1 | 1 |
| Friction type silica 1 | 5 | 8 | 10 | 15 | 20 |
| Thickening silica | 10 | 8 | 7 | 3 | 0 |
| Cellulose gum | 0.4 | 0.4 | 0.6 | 0.4 | 0.4 |
| Xanthan gum | 0.3 | 0.3 | 0.4 | 0.3 | 0.3 |
| Saccharin sodium salt | 0.2 | 0.2 | 0.2 | 0.2 | 0.2 |
| Sodium fluoride | 0.14 | 0.14 | 0.14 | 0.14 | 0.14 |
| Sodium benzoate | 0.3 | 0.3 | 0.3 | 0.3 | 0.3 |
| Essence | 0.8 | 0.8 | 0.8 | 0.8 | 0.8 |
| Water (W) | Allowance of | Allowance of | Allowance of | Allowance of | Balance of |
| Ra value | 0.371 | 0.414 | 0.456 | 0.599 | 0.650 |
Example 4
According to the development characteristics of children's teeth, it is mainly divided into three stages of primary tooth eruption stage, primary tooth arrangement stage and mixed tooth (replacement) arrangement stage. The mixed (replacement) dentition period is divided into a mixed dentition early period and a mixed dentition late period. The caries rate of children is high due to dietary structure and dietary components of the children, and although the consciousness of oral care of the children is gradually improved, the cleaning efficiency of tooth brushing is low and the teeth are not cleaned in place. The oral cavity conditions are different in different age groups, and the condition of the yellow teeth is different, so that the teeth can be brushed cleanly by normal tooth brushing. The mineralization degree and enamel looseness of teeth in different ages are different, for example, the mineralization degree of deciduous teeth is low, the enamel looseness is high, the cleaning power of used oral products is different, and mild and effective tooth refreshing is realized on the premise of not damaging the teeth. There is currently no relevant standard requirement regarding the cleaning power or wear value of a toothpaste.
By statistically significant analysis of the RDA and PCR values measured for the different protocol toothpaste preparations of example 1, the results suggest that the higher the PCR value measured for the same silica abrasive, such as protocols 1-3 or protocols 4-6, the higher the RDA value. The differential design of the toothpaste abrasion value RDA can be realized by changing different abrasive material proportions.
Grading of different intervals of toothpaste abrasion value RDA can be achieved by analysis of abrasion value tests for different types of silica abrasives with RDA values of about 30-50, 50-70, 70-90, and PCR values of about 60-80, 80-100, 100-120. For example, protocol 1 and protocol 2, protocol 2 and protocol 3, protocol 4 and protocol 5, and protocol 5 and protocol 6, all groups with significant differences (p < 0.05) between the RDA and PCR values of the 4 tested protocol groups, with a difference in wear values between the two in a statistical sense.
By combining the characteristics of tooth development of children in different age groups, the RDA grading method of the embodiment can be adopted to develop toothpaste products suitable for children in different age groups, and the aim of efficiently and safely cleaning teeth is fulfilled.
Breast dentition stage: the milk teeth erupt completely about 3 years old, the mineralization degree of the milk teeth is lower than that of the permanent teeth, the acid resistance is weak, the enamel and the dentin are thin, and the decayed teeth are easy to occur. In the age group with high incidence of dental caries at 5 years, reasonable diet should be paid attention to encourage children to eat more fibrous food to enhance chewing function. Furthermore, the neck of the deciduous tooth is obviously contracted, the 1/3 part of the crown close to the neck is raised, the contact between adjacent teeth is surface contact, physiological gaps exist in dentition, and spot gaps and grooves of the crown part are easy to retain bacterial plaque and food residues, so that the teeth become dirty areas. While this phase is in a phase of significantly improved brushing ability, the brushing regimen is often not fully mastered and parents must continue to assist children in brushing their teeth. Therefore, the anatomical morphology, the tissue structure and the mineralization degree of the formed deciduous teeth in the age group are aimed at, namely the mineralization degree of the deciduous teeth is low, the thickness of the teeth is thin, so that the just erupted deciduous teeth are very young and tender, and a milder oral care mode is needed. Plaque removal by brushing is the best cleaning method, and toothpaste suitable for this stage should have a certain cleaning effect without damaging enamel, and match the use of children's toothpaste in the RDA30-50 range.
The early stage of mixed dentition: it is referred to as the eruption of the first permanent molars to the replacement of incisors, and the process of replacing teeth is mainly focused at this stage. The deciduous teeth begin to fall off in the period of replacing teeth, the permanent teeth begin to sprout, the incidence rate of the deciduous tooth caries is still high, and the newly-emerged permanent teeth are easy to generate caries. Temporary malocclusion and irregular dentition can occur in the replacement process of deciduous permanent teeth, and the cleanness of the oral cavity is difficult to keep. The prominent sign of this stage is that the child has increased responsibility, is able to brush and floss themselves, and parents help clean hard-to-reach areas. The mineralization degree of hard tissues of young permanent teeth is lower than that of mature permanent tooth enamel, and the teeth can be mineralized further only after erupting for about 2 years, so that the teeth are susceptible to caries within 2 years of new eruption. With the change of eating habits, the consumption of various beverages, especially carbonated beverages, increases, resulting in increased dental erosion, especially in young permanent teeth of children and teenagers, with a growing trend. Therefore, there is a need to focus on oral hygiene and tooth cleaning, matching the use of children's toothpaste in the range of RDA50-70, which is a higher level of cleaning.
Late stage of mixed dentition: the replacement period of the lateral group is referred to, and the permanent cuspid teeth and the first and second premolars are clinically called the lateral group, and the replacement of the lateral group starts from 9 years and half to 12 years old or so. Crowding of the lower incisors and clearance of the upper incisors improve during this period. The permanent tooth dysplasia needs to be prevented and treated in time, tooth trauma is prevented and treated, permanent tooth caries is prevented, bad oral habits are corrected, and malformation caused by mistake is corrected in an early stage. The mineralization degree of the teeth at this stage is improved to a certain extent, so that the children toothpaste product with higher cleaning effect can be used, the teeth can be cleaned more efficiently, dental plaque can be removed, and the occurrence of dental caries can be prevented. The data were analyzed in conjunction with a systematic study of the abrasion values of toothpastes containing different types of silica abrasives, matching the use of a children's toothpaste in the RDA70-90 range class.
In conclusion, the invention provides a grading standard of RDA values of the children toothpaste according to the test results of the toothpaste abrasion performance quick evaluation model, systematically researches the abrasion values of the soft silica under different types and dosages, statistically significant analysis is carried out on the obtained RDA values, and simultaneously, the grading intervals of RDA30-50 (deciduous dentition period), RDA50-70 (early mixed dentition period) and RDA70-90 (late mixed dentition period) of the children toothpaste matched with different tooth development stages are established by combining the RDA value interval range of the children toothpaste at home and abroad and the deviation factors of the detection data.
The above description is only a preferred embodiment of the present invention, and is not intended to limit the scope of the present invention, and all modifications and equivalents of the present invention, which are made by the present specification and directly/indirectly applied to other related technical fields within the spirit of the present invention are included in the scope of the present invention.
Claims (9)
1. A method for evaluating the abrasion performance of a toothpaste, comprising the steps of:
step 1: screening the types of the silica which is suitable for the transparent toothpaste for children and has proper friction, applying the silica with different types and different dosages to the basic formula of the transparent toothpaste for children, and keeping the dosages of other formula components unchanged.
And 2, step: preparing a series of toothpaste samples according to the step 1, respectively testing the Ra value of the toothpaste by adopting a GB/T35832 toothpaste friction value Ra detection method, testing the cleaning power PCR value of the toothpaste by adopting a biomembrane cleaning rate PCR test method, and simultaneously testing the RDA value of each toothpaste by adopting an ISO11609 radioactive tracer method.
And step 3:performing data fitting analysis on the RDA value and the Ra value obtained by testing each toothpaste sample in the step 2, and establishing a children toothpaste wear performance evaluation model: RDA =107.2Ra +11.553, linear correlation coefficient R 2 Is 0.9176.
And 4, step 4: and evaluating the wear performance of the toothpaste for children according to the evaluation model.
2. The method of evaluating the abrasion performance of toothpaste according to claim 1, wherein: the screening in the step 1 is suitable for models of silica with proper friction of the transparent toothpaste for children, specifically, friction type silica and thickening type silica with different models are selected, the mass percentage content of the friction type silica of each model is sequentially increased, and correspondingly, the mass percentage content of the thickening type silica is sequentially decreased.
3. The method of evaluating the abrasion performance of toothpaste according to claim 1, wherein: and in the step 3, data fitting analysis is carried out by adopting statistical software SPSS to obtain the RDA value and the Ra value to carry out a data fitting equation.
4. A toothpaste formulation obtained by the method for evaluating the abrasion performance of toothpaste according to any one of claims 1 to 4, which comprises the following components:
the percentage is that each component accounts for the total weight of the formula.
5. A children toothpaste RDA grading method is characterized by comprising the following steps:
step 1: the models of silica with proper friction suitable for the transparent toothpaste for children are screened, and the silica with different models and different dosages is applied to the basic formula of the transparent toothpaste for children, and the dosages of other formula components are kept unchanged.
Step 2: preparing a series of toothpaste samples according to the step 1, and testing the Ra value of the toothpaste by respectively adopting a GB/T35832 toothpaste friction value Ra detection method and testing the cleaning power PCR value of the toothpaste by adopting a biomembrane cleaning rate PCR detection method.
And step 3: performing data fitting analysis on the RDA value and the Ra value obtained by testing each toothpaste sample in the step 2, and establishing a children toothpaste wear performance evaluation model: RDA =107.2Ra +11.553, linear correlation coefficient R 2 Is 0.9176.
And 4, step 4: according to the evaluation model of the wear performance of the children toothpaste, the wear performance of the children toothpaste is classified into 3 grades, namely RDA30-50, RDA50-70 and RDA70-90.
6. The method for grading a children's toothpaste RDA according to claim 5, wherein: the screening in the step 1 is suitable for the types of the silica with proper friction of the transparent toothpaste for children, specifically, friction type silica and thickening type silica of different types are selected, the mass percentage content of the friction type silica of each type is sequentially increased, and correspondingly, the mass percentage content of the thickening type silica is sequentially decreased.
7. The method for grading a children's toothpaste RDA according to claim 5, wherein: and in the step 3, data fitting analysis is carried out by adopting statistical software SPSS to obtain the RDA value and the Ra value to carry out a data fitting equation.
8. A design method of a children toothpaste formula is characterized by comprising the following steps:
step 1: screening the types of the silica which is suitable for the transparent toothpaste for children and has proper friction, applying the silica with different types and different dosages to the basic formula of the transparent toothpaste for children, and keeping the dosages of other formula components unchanged.
And 2, step: preparing a series of toothpaste samples according to the step 1, and respectively testing the Ra value of the toothpaste by adopting a GB/T35832 toothpaste friction value Ra detection method and testing the cleaning power PCR value of the toothpaste by adopting a biomembrane cleaning rate PCR detection method.
And step 3: calculating the Ra value obtained by testing each toothpaste sample in the step 2 by adopting a children toothpaste wear performance evaluation model to obtain the RDA value of each toothpaste sample: RDA =107.2Ra +11.553, linear correlation coefficient R 2 Was 0.9176.
And 4, step 4: and (3) obtaining the RDA value of each toothpaste sample according to the step (3), judging whether the RDA value meets the design requirement to obtain a toothpaste formula, if not, changing different abrasive proportions and repeating the steps (1-3) until the RDA value meets the design requirement.
9. The method of claim 8, wherein the toothpaste comprises the following components:
the percentage is that each component accounts for the total weight of the formula.
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