CN115607462A - Pre-dispersed calcium ions, pre-dispersion method thereof and application of pre-dispersed calcium ions in depilatory products - Google Patents
Pre-dispersed calcium ions, pre-dispersion method thereof and application of pre-dispersed calcium ions in depilatory products Download PDFInfo
- Publication number
- CN115607462A CN115607462A CN202211249007.8A CN202211249007A CN115607462A CN 115607462 A CN115607462 A CN 115607462A CN 202211249007 A CN202211249007 A CN 202211249007A CN 115607462 A CN115607462 A CN 115607462A
- Authority
- CN
- China
- Prior art keywords
- parts
- calcium ions
- calcium
- phase
- oil
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 title claims abstract description 91
- 229910001424 calcium ion Inorganic materials 0.000 title claims abstract description 91
- 238000000034 method Methods 0.000 title claims abstract description 20
- 230000002951 depilatory effect Effects 0.000 title abstract description 79
- 239000006185 dispersion Substances 0.000 title description 8
- CWERGRDVMFNCDR-UHFFFAOYSA-N thioglycolic acid Chemical compound OC(=O)CS CWERGRDVMFNCDR-UHFFFAOYSA-N 0.000 claims abstract description 72
- 239000003995 emulsifying agent Substances 0.000 claims abstract description 27
- 239000004519 grease Substances 0.000 claims abstract description 27
- 239000002994 raw material Substances 0.000 claims abstract description 24
- 230000008719 thickening Effects 0.000 claims abstract description 23
- 239000003381 stabilizer Substances 0.000 claims abstract description 21
- 238000002360 preparation method Methods 0.000 claims abstract description 14
- 238000003756 stirring Methods 0.000 claims description 39
- 239000003921 oil Substances 0.000 claims description 31
- 235000019198 oils Nutrition 0.000 claims description 31
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 claims description 27
- -1 stearyloxy Chemical group 0.000 claims description 24
- 239000002245 particle Substances 0.000 claims description 15
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 15
- 239000003963 antioxidant agent Substances 0.000 claims description 13
- 230000003078 antioxidant effect Effects 0.000 claims description 13
- 235000015112 vegetable and seed oil Nutrition 0.000 claims description 13
- 239000004215 Carbon black (E152) Substances 0.000 claims description 11
- 235000014113 dietary fatty acids Nutrition 0.000 claims description 11
- 239000000194 fatty acid Substances 0.000 claims description 11
- 229930195729 fatty acid Natural products 0.000 claims description 11
- 229930195733 hydrocarbon Natural products 0.000 claims description 11
- 150000002430 hydrocarbons Chemical class 0.000 claims description 11
- 150000002191 fatty alcohols Chemical class 0.000 claims description 10
- 239000004354 Hydroxyethyl cellulose Substances 0.000 claims description 9
- 229920000663 Hydroxyethyl cellulose Polymers 0.000 claims description 9
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 9
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 claims description 9
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 8
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 7
- 239000002738 chelating agent Substances 0.000 claims description 7
- 150000004665 fatty acids Chemical class 0.000 claims description 7
- 238000002156 mixing Methods 0.000 claims description 7
- SVTBMSDMJJWYQN-UHFFFAOYSA-N 2-methylpentane-2,4-diol Chemical compound CC(O)CC(C)(C)O SVTBMSDMJJWYQN-UHFFFAOYSA-N 0.000 claims description 6
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims description 6
- 239000004166 Lanolin Substances 0.000 claims description 5
- 241001465754 Metazoa Species 0.000 claims description 5
- 229940039717 lanolin Drugs 0.000 claims description 5
- 235000019388 lanolin Nutrition 0.000 claims description 5
- 239000003755 preservative agent Substances 0.000 claims description 5
- 230000002335 preservative effect Effects 0.000 claims description 5
- 239000004698 Polyethylene Substances 0.000 claims description 4
- OSGAYBCDTDRGGQ-UHFFFAOYSA-L calcium sulfate Chemical compound [Ca+2].[O-]S([O-])(=O)=O OSGAYBCDTDRGGQ-UHFFFAOYSA-L 0.000 claims description 4
- 239000000945 filler Substances 0.000 claims description 4
- 229920000573 polyethylene Polymers 0.000 claims description 4
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 claims description 3
- 229940043375 1,5-pentanediol Drugs 0.000 claims description 3
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 claims description 3
- RWLALWYNXFYRGW-UHFFFAOYSA-N 2-Ethyl-1,3-hexanediol Chemical compound CCCC(O)C(CC)CO RWLALWYNXFYRGW-UHFFFAOYSA-N 0.000 claims description 3
- QCDWFXQBSFUVSP-UHFFFAOYSA-N 2-phenoxyethanol Chemical compound OCCOC1=CC=CC=C1 QCDWFXQBSFUVSP-UHFFFAOYSA-N 0.000 claims description 3
- NIXOWILDQLNWCW-UHFFFAOYSA-N Acrylic acid Chemical compound OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims description 3
- 229920002134 Carboxymethyl cellulose Polymers 0.000 claims description 3
- 229920002785 Croscarmellose sodium Polymers 0.000 claims description 3
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims description 3
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 claims description 3
- 239000001856 Ethyl cellulose Substances 0.000 claims description 3
- ZZSNKZQZMQGXPY-UHFFFAOYSA-N Ethyl cellulose Chemical compound CCOCC1OC(OC)C(OCC)C(OCC)C1OC1C(O)C(O)C(OC)C(CO)O1 ZZSNKZQZMQGXPY-UHFFFAOYSA-N 0.000 claims description 3
- 108010010803 Gelatin Proteins 0.000 claims description 3
- 229920002148 Gellan gum Polymers 0.000 claims description 3
- 229920001479 Hydroxyethyl methyl cellulose Polymers 0.000 claims description 3
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 claims description 3
- 229910019142 PO4 Inorganic materials 0.000 claims description 3
- 239000002202 Polyethylene glycol Substances 0.000 claims description 3
- 239000004372 Polyvinyl alcohol Substances 0.000 claims description 3
- 229920002125 Sokalan® Polymers 0.000 claims description 3
- 238000005054 agglomeration Methods 0.000 claims description 3
- 230000002776 aggregation Effects 0.000 claims description 3
- SNAAJJQQZSMGQD-UHFFFAOYSA-N aluminum magnesium Chemical compound [Mg].[Al] SNAAJJQQZSMGQD-UHFFFAOYSA-N 0.000 claims description 3
- 239000010775 animal oil Substances 0.000 claims description 3
- BRPQOXSCLDDYGP-UHFFFAOYSA-N calcium oxide Chemical compound [O-2].[Ca+2] BRPQOXSCLDDYGP-UHFFFAOYSA-N 0.000 claims description 3
- 239000000292 calcium oxide Substances 0.000 claims description 3
- ODINCKMPIJJUCX-UHFFFAOYSA-N calcium oxide Inorganic materials [Ca]=O ODINCKMPIJJUCX-UHFFFAOYSA-N 0.000 claims description 3
- 229960001631 carbomer Drugs 0.000 claims description 3
- 239000001768 carboxy methyl cellulose Substances 0.000 claims description 3
- 235000010948 carboxy methyl cellulose Nutrition 0.000 claims description 3
- 229920003090 carboxymethyl hydroxyethyl cellulose Polymers 0.000 claims description 3
- 150000005690 diesters Chemical class 0.000 claims description 3
- 229960004756 ethanol Drugs 0.000 claims description 3
- 229920001249 ethyl cellulose Polymers 0.000 claims description 3
- 235000019325 ethyl cellulose Nutrition 0.000 claims description 3
- 229960005082 etohexadiol Drugs 0.000 claims description 3
- 229920000159 gelatin Polymers 0.000 claims description 3
- 239000008273 gelatin Substances 0.000 claims description 3
- 235000019322 gelatine Nutrition 0.000 claims description 3
- 235000011852 gelatine desserts Nutrition 0.000 claims description 3
- 235000010492 gellan gum Nutrition 0.000 claims description 3
- 239000000216 gellan gum Substances 0.000 claims description 3
- 235000011187 glycerol Nutrition 0.000 claims description 3
- 229930182470 glycoside Natural products 0.000 claims description 3
- 229940051250 hexylene glycol Drugs 0.000 claims description 3
- 229920013819 hydroxyethyl ethylcellulose Polymers 0.000 claims description 3
- 239000001863 hydroxypropyl cellulose Substances 0.000 claims description 3
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 claims description 3
- 229920013818 hydroxypropyl guar gum Polymers 0.000 claims description 3
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 claims description 3
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 claims description 3
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 claims description 3
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 claims description 3
- WCVRQHFDJLLWFE-UHFFFAOYSA-N pentane-1,2-diol Chemical compound CCCC(O)CO WCVRQHFDJLLWFE-UHFFFAOYSA-N 0.000 claims description 3
- 229960005323 phenoxyethanol Drugs 0.000 claims description 3
- 239000010452 phosphate Substances 0.000 claims description 3
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 claims description 3
- 229920001223 polyethylene glycol Polymers 0.000 claims description 3
- 229940051841 polyoxyethylene ether Drugs 0.000 claims description 3
- 229920000056 polyoxyethylene ether Polymers 0.000 claims description 3
- 229920002451 polyvinyl alcohol Polymers 0.000 claims description 3
- 150000003839 salts Chemical class 0.000 claims description 3
- 235000010413 sodium alginate Nutrition 0.000 claims description 3
- 239000000661 sodium alginate Substances 0.000 claims description 3
- 229940005550 sodium alginate Drugs 0.000 claims description 3
- 239000000600 sorbitol Substances 0.000 claims description 3
- 239000008158 vegetable oil Substances 0.000 claims description 3
- 239000000230 xanthan gum Substances 0.000 claims description 3
- 235000010493 xanthan gum Nutrition 0.000 claims description 3
- 229920001285 xanthan gum Polymers 0.000 claims description 3
- 229940082509 xanthan gum Drugs 0.000 claims description 3
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 claims description 2
- 239000001110 calcium chloride Substances 0.000 claims description 2
- 229910001628 calcium chloride Inorganic materials 0.000 claims description 2
- FNAQSUUGMSOBHW-UHFFFAOYSA-H calcium citrate Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O.[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O FNAQSUUGMSOBHW-UHFFFAOYSA-H 0.000 claims description 2
- 239000001354 calcium citrate Substances 0.000 claims description 2
- AXCZMVOFGPJBDE-UHFFFAOYSA-L calcium dihydroxide Chemical compound [OH-].[OH-].[Ca+2] AXCZMVOFGPJBDE-UHFFFAOYSA-L 0.000 claims description 2
- 239000000920 calcium hydroxide Substances 0.000 claims description 2
- 229910001861 calcium hydroxide Inorganic materials 0.000 claims description 2
- 239000000203 mixture Substances 0.000 claims description 2
- 235000013337 tricalcium citrate Nutrition 0.000 claims description 2
- CNYFJCCVJNARLE-UHFFFAOYSA-L calcium;2-sulfanylacetic acid;2-sulfidoacetate Chemical compound [Ca+2].[O-]C(=O)CS.[O-]C(=O)CS CNYFJCCVJNARLE-UHFFFAOYSA-L 0.000 abstract description 26
- 230000035617 depilation Effects 0.000 abstract description 15
- 230000008569 process Effects 0.000 abstract description 9
- 238000004519 manufacturing process Methods 0.000 abstract description 5
- CWERGRDVMFNCDR-UHFFFAOYSA-M thioglycolate(1-) Chemical compound [O-]C(=O)CS CWERGRDVMFNCDR-UHFFFAOYSA-M 0.000 abstract description 3
- 238000005524 ceramic coating Methods 0.000 abstract description 2
- 239000000047 product Substances 0.000 description 75
- 230000007794 irritation Effects 0.000 description 19
- 210000004209 hair Anatomy 0.000 description 17
- 238000001816 cooling Methods 0.000 description 12
- VBICKXHEKHSIBG-UHFFFAOYSA-N 1-monostearoylglycerol Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(O)CO VBICKXHEKHSIBG-UHFFFAOYSA-N 0.000 description 10
- GLDOVTGHNKAZLK-UHFFFAOYSA-N octadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCO GLDOVTGHNKAZLK-UHFFFAOYSA-N 0.000 description 10
- 239000000126 substance Substances 0.000 description 10
- BANXPJUEBPWEOT-UHFFFAOYSA-N 2-methyl-Pentadecane Chemical compound CCCCCCCCCCCCCC(C)C BANXPJUEBPWEOT-UHFFFAOYSA-N 0.000 description 8
- MWKFXSUHUHTGQN-UHFFFAOYSA-N decan-1-ol Chemical compound CCCCCCCCCCO MWKFXSUHUHTGQN-UHFFFAOYSA-N 0.000 description 8
- SHZIWNPUGXLXDT-UHFFFAOYSA-N ethyl hexanoate Chemical compound CCCCCC(=O)OCC SHZIWNPUGXLXDT-UHFFFAOYSA-N 0.000 description 8
- 235000019197 fats Nutrition 0.000 description 8
- HLZKNKRTKFSKGZ-UHFFFAOYSA-N tetradecan-1-ol Chemical compound CCCCCCCCCCCCCCO HLZKNKRTKFSKGZ-UHFFFAOYSA-N 0.000 description 8
- 240000001548 Camellia japonica Species 0.000 description 6
- 235000018597 common camellia Nutrition 0.000 description 6
- 230000000052 comparative effect Effects 0.000 description 6
- 239000004205 dimethyl polysiloxane Substances 0.000 description 6
- 235000013870 dimethyl polysiloxane Nutrition 0.000 description 6
- 235000013399 edible fruits Nutrition 0.000 description 6
- 230000000694 effects Effects 0.000 description 6
- 239000002480 mineral oil Substances 0.000 description 6
- 235000010446 mineral oil Nutrition 0.000 description 6
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 description 6
- 210000003491 skin Anatomy 0.000 description 6
- KBPLFHHGFOOTCA-UHFFFAOYSA-N 1-Octanol Chemical compound CCCCCCCCO KBPLFHHGFOOTCA-UHFFFAOYSA-N 0.000 description 4
- 229940043268 2,2,4,4,6,8,8-heptamethylnonane Drugs 0.000 description 4
- 244000179886 Moringa oleifera Species 0.000 description 4
- 235000011347 Moringa oleifera Nutrition 0.000 description 4
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 4
- DWAQJAXMDSEUJJ-UHFFFAOYSA-M Sodium bisulfite Chemical compound [Na+].OS([O-])=O DWAQJAXMDSEUJJ-UHFFFAOYSA-M 0.000 description 4
- 238000007599 discharging Methods 0.000 description 4
- POULHZVOKOAJMA-UHFFFAOYSA-N dodecanoic acid Chemical compound CCCCCCCCCCCC(O)=O POULHZVOKOAJMA-UHFFFAOYSA-N 0.000 description 4
- 229940075529 glyceryl stearate Drugs 0.000 description 4
- 239000008169 grapeseed oil Substances 0.000 description 4
- 238000010438 heat treatment Methods 0.000 description 4
- BXWNKGSJHAJOGX-UHFFFAOYSA-N hexadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCO BXWNKGSJHAJOGX-UHFFFAOYSA-N 0.000 description 4
- CBFCDTFDPHXCNY-UHFFFAOYSA-N icosane Chemical compound CCCCCCCCCCCCCCCCCCCC CBFCDTFDPHXCNY-UHFFFAOYSA-N 0.000 description 4
- VKOBVWXKNCXXDE-UHFFFAOYSA-N icosanoic acid Chemical compound CCCCCCCCCCCCCCCCCCCC(O)=O VKOBVWXKNCXXDE-UHFFFAOYSA-N 0.000 description 4
- KUVMKLCGXIYSNH-UHFFFAOYSA-N isopentadecane Natural products CCCCCCCCCCCCC(C)C KUVMKLCGXIYSNH-UHFFFAOYSA-N 0.000 description 4
- 229940119170 jojoba wax Drugs 0.000 description 4
- 229940043348 myristyl alcohol Drugs 0.000 description 4
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 4
- SECPZKHBENQXJG-FPLPWBNLSA-N palmitoleic acid Chemical compound CCCCCC\C=C/CCCCCCCC(O)=O SECPZKHBENQXJG-FPLPWBNLSA-N 0.000 description 4
- 229920002545 silicone oil Polymers 0.000 description 4
- 235000010267 sodium hydrogen sulphite Nutrition 0.000 description 4
- PRAKJMSDJKAYCZ-UHFFFAOYSA-N squalane Chemical compound CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C PRAKJMSDJKAYCZ-UHFFFAOYSA-N 0.000 description 4
- AGNTUZCMJBTHOG-UHFFFAOYSA-N 3-[3-(2,3-dihydroxypropoxy)-2-hydroxypropoxy]propane-1,2-diol Chemical compound OCC(O)COCC(O)COCC(O)CO AGNTUZCMJBTHOG-UHFFFAOYSA-N 0.000 description 3
- 208000002193 Pain Diseases 0.000 description 3
- 235000021355 Stearic acid Nutrition 0.000 description 3
- 235000018936 Vitellaria paradoxa Nutrition 0.000 description 3
- 241001135917 Vitellaria paradoxa Species 0.000 description 3
- 239000002253 acid Substances 0.000 description 3
- 229940081733 cetearyl alcohol Drugs 0.000 description 3
- 229940082500 cetostearyl alcohol Drugs 0.000 description 3
- 235000019868 cocoa butter Nutrition 0.000 description 3
- 229940110456 cocoa butter Drugs 0.000 description 3
- 239000006071 cream Substances 0.000 description 3
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 description 3
- 229940057910 shea butter Drugs 0.000 description 3
- 239000008117 stearic acid Substances 0.000 description 3
- 238000012360 testing method Methods 0.000 description 3
- OULAJFUGPPVRBK-UHFFFAOYSA-N tetratriacontyl alcohol Natural products CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCO OULAJFUGPPVRBK-UHFFFAOYSA-N 0.000 description 3
- 210000000707 wrist Anatomy 0.000 description 3
- DSEKYWAQQVUQTP-XEWMWGOFSA-N (2r,4r,4as,6as,6as,6br,8ar,12ar,14as,14bs)-2-hydroxy-4,4a,6a,6b,8a,11,11,14a-octamethyl-2,4,5,6,6a,7,8,9,10,12,12a,13,14,14b-tetradecahydro-1h-picen-3-one Chemical compound C([C@H]1[C@]2(C)CC[C@@]34C)C(C)(C)CC[C@]1(C)CC[C@]2(C)[C@H]4CC[C@@]1(C)[C@H]3C[C@@H](O)C(=O)[C@@H]1C DSEKYWAQQVUQTP-XEWMWGOFSA-N 0.000 description 2
- ALSTYHKOOCGGFT-KTKRTIGZSA-N (9Z)-octadecen-1-ol Chemical compound CCCCCCCC\C=C/CCCCCCCCO ALSTYHKOOCGGFT-KTKRTIGZSA-N 0.000 description 2
- WRIDQFICGBMAFQ-UHFFFAOYSA-N (E)-8-Octadecenoic acid Natural products CCCCCCCCCC=CCCCCCCC(O)=O WRIDQFICGBMAFQ-UHFFFAOYSA-N 0.000 description 2
- LDVVTQMJQSCDMK-UHFFFAOYSA-N 1,3-dihydroxypropan-2-yl formate Chemical compound OCC(CO)OC=O LDVVTQMJQSCDMK-UHFFFAOYSA-N 0.000 description 2
- WAYINTBTZWQNSN-UHFFFAOYSA-N 11-methyldodecyl 3,5,5-trimethylhexanoate Chemical compound CC(C)CCCCCCCCCCOC(=O)CC(C)CC(C)(C)C WAYINTBTZWQNSN-UHFFFAOYSA-N 0.000 description 2
- FUWVMBCPMRAWPG-UHFFFAOYSA-N 2,3-dihydroxypropyl 2-hydroxyoctadecanoate Chemical compound CCCCCCCCCCCCCCCCC(O)C(=O)OCC(O)CO FUWVMBCPMRAWPG-UHFFFAOYSA-N 0.000 description 2
- GTJOHISYCKPIMT-UHFFFAOYSA-N 2-methylundecane Chemical compound CCCCCCCCCC(C)C GTJOHISYCKPIMT-UHFFFAOYSA-N 0.000 description 2
- WHBKVWBGTBULQY-UHFFFAOYSA-N 2-propylheptyl octanoate Chemical compound CCCCCCCC(=O)OCC(CCC)CCCCC WHBKVWBGTBULQY-UHFFFAOYSA-N 0.000 description 2
- LQJBNNIYVWPHFW-UHFFFAOYSA-N 20:1omega9c fatty acid Natural products CCCCCCCCCCC=CCCCCCCCC(O)=O LQJBNNIYVWPHFW-UHFFFAOYSA-N 0.000 description 2
- UIVPNOBLHXUKDX-UHFFFAOYSA-N 3,5,5-trimethylhexyl 3,5,5-trimethylhexanoate Chemical compound CC(C)(C)CC(C)CCOC(=O)CC(C)CC(C)(C)C UIVPNOBLHXUKDX-UHFFFAOYSA-N 0.000 description 2
- HIQIXEFWDLTDED-UHFFFAOYSA-N 4-hydroxy-1-piperidin-4-ylpyrrolidin-2-one Chemical compound O=C1CC(O)CN1C1CCNCC1 HIQIXEFWDLTDED-UHFFFAOYSA-N 0.000 description 2
- AMUTYVGRCVFCCD-UHFFFAOYSA-N 5,6-diaminopyridine-3-carboxylic acid Chemical compound NC1=CC(C(O)=O)=CN=C1N AMUTYVGRCVFCCD-UHFFFAOYSA-N 0.000 description 2
- SAUIGQBKPDQYHL-QXMHVHEDSA-N 6-methylheptyl (z)-octadec-9-enoate Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OCCCCCC(C)C SAUIGQBKPDQYHL-QXMHVHEDSA-N 0.000 description 2
- QSBYPNXLFMSGKH-UHFFFAOYSA-N 9-Heptadecensaeure Natural products CCCCCCCC=CCCCCCCCC(O)=O QSBYPNXLFMSGKH-UHFFFAOYSA-N 0.000 description 2
- 235000009434 Actinidia chinensis Nutrition 0.000 description 2
- 244000298697 Actinidia deliciosa Species 0.000 description 2
- 235000009436 Actinidia deliciosa Nutrition 0.000 description 2
- 244000144725 Amygdalus communis Species 0.000 description 2
- 235000011437 Amygdalus communis Nutrition 0.000 description 2
- 235000019737 Animal fat Nutrition 0.000 description 2
- 235000004936 Bromus mango Nutrition 0.000 description 2
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 2
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 2
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 description 2
- SGVYKUFIHHTIFL-UHFFFAOYSA-N Isobutylhexyl Natural products CCCCCCCC(C)C SGVYKUFIHHTIFL-UHFFFAOYSA-N 0.000 description 2
- 108010076876 Keratins Proteins 0.000 description 2
- 102000011782 Keratins Human genes 0.000 description 2
- 239000005639 Lauric acid Substances 0.000 description 2
- OYHQOLUKZRVURQ-HZJYTTRNSA-N Linoleic acid Chemical compound CCCCC\C=C/C\C=C/CCCCCCCC(O)=O OYHQOLUKZRVURQ-HZJYTTRNSA-N 0.000 description 2
- 235000018330 Macadamia integrifolia Nutrition 0.000 description 2
- 240000000912 Macadamia tetraphylla Species 0.000 description 2
- 235000003800 Macadamia tetraphylla Nutrition 0.000 description 2
- 240000007228 Mangifera indica Species 0.000 description 2
- 235000014826 Mangifera indica Nutrition 0.000 description 2
- 239000005642 Oleic acid Substances 0.000 description 2
- ZQPPMHVWECSIRJ-UHFFFAOYSA-N Oleic acid Natural products CCCCCCCCC=CCCCCCCCC(O)=O ZQPPMHVWECSIRJ-UHFFFAOYSA-N 0.000 description 2
- 235000021319 Palmitoleic acid Nutrition 0.000 description 2
- 239000004264 Petrolatum Substances 0.000 description 2
- 235000000539 Rosa canina Nutrition 0.000 description 2
- 240000008530 Rosa canina Species 0.000 description 2
- 206010040914 Skin reaction Diseases 0.000 description 2
- 235000009184 Spondias indica Nutrition 0.000 description 2
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 description 2
- UWHZIFQPPBDJPM-FPLPWBNLSA-M Vaccenic acid Natural products CCCCCC\C=C/CCCCCCCCCC([O-])=O UWHZIFQPPBDJPM-FPLPWBNLSA-M 0.000 description 2
- 235000021322 Vaccenic acid Nutrition 0.000 description 2
- XLOMVQKBTHCTTD-UHFFFAOYSA-N Zinc monoxide Chemical compound [Zn]=O XLOMVQKBTHCTTD-UHFFFAOYSA-N 0.000 description 2
- FSEJJKIPRNUIFL-UHFFFAOYSA-N [2,2-bis(hydroxymethyl)-3-octadecanoyloxypropyl] octadecanoate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(CO)(CO)COC(=O)CCCCCCCCCCCCCCCCC FSEJJKIPRNUIFL-UHFFFAOYSA-N 0.000 description 2
- LPGFSDGXTDNTCB-UHFFFAOYSA-N [3-(16-methylheptadecanoyloxy)-2,2-bis(16-methylheptadecanoyloxymethyl)propyl] 16-methylheptadecanoate Chemical compound CC(C)CCCCCCCCCCCCCCC(=O)OCC(COC(=O)CCCCCCCCCCCCCCC(C)C)(COC(=O)CCCCCCCCCCCCCCC(C)C)COC(=O)CCCCCCCCCCCCCCC(C)C LPGFSDGXTDNTCB-UHFFFAOYSA-N 0.000 description 2
- DRRMRHKHTQRWMB-UHFFFAOYSA-N [3-(2-ethylhexanoyloxy)-2,2-bis(2-ethylhexanoyloxymethyl)propyl] 2-ethylhexanoate Chemical compound CCCCC(CC)C(=O)OCC(COC(=O)C(CC)CCCC)(COC(=O)C(CC)CCCC)COC(=O)C(CC)CCCC DRRMRHKHTQRWMB-UHFFFAOYSA-N 0.000 description 2
- 150000001335 aliphatic alkanes Chemical class 0.000 description 2
- 239000008168 almond oil Substances 0.000 description 2
- 235000021302 avocado oil Nutrition 0.000 description 2
- 239000008163 avocado oil Substances 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- HGKOWIQVWAQWDS-UHFFFAOYSA-N bis(16-methylheptadecyl) 2-hydroxybutanedioate Chemical compound CC(C)CCCCCCCCCCCCCCCOC(=O)CC(O)C(=O)OCCCCCCCCCCCCCCCC(C)C HGKOWIQVWAQWDS-UHFFFAOYSA-N 0.000 description 2
- 235000021324 borage oil Nutrition 0.000 description 2
- 239000010474 borage seed oil Substances 0.000 description 2
- 239000011575 calcium Substances 0.000 description 2
- 229910052791 calcium Inorganic materials 0.000 description 2
- 239000004359 castor oil Substances 0.000 description 2
- 235000019438 castor oil Nutrition 0.000 description 2
- 229960000541 cetyl alcohol Drugs 0.000 description 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 2
- SECPZKHBENQXJG-UHFFFAOYSA-N cis-palmitoleic acid Natural products CCCCCCC=CCCCCCCCC(O)=O SECPZKHBENQXJG-UHFFFAOYSA-N 0.000 description 2
- 229940071160 cocoate Drugs 0.000 description 2
- 239000003240 coconut oil Substances 0.000 description 2
- 235000019864 coconut oil Nutrition 0.000 description 2
- SASYSVUEVMOWPL-NXVVXOECSA-N decyl oleate Chemical compound CCCCCCCCCCOC(=O)CCCCCCC\C=C/CCCCCCCC SASYSVUEVMOWPL-NXVVXOECSA-N 0.000 description 2
- QDOXWKRWXJOMAK-UHFFFAOYSA-N dichromium trioxide Chemical compound O=[Cr]O[Cr]=O QDOXWKRWXJOMAK-UHFFFAOYSA-N 0.000 description 2
- PKPOVTYZGGYDIJ-UHFFFAOYSA-N dioctyl carbonate Chemical compound CCCCCCCCOC(=O)OCCCCCCCC PKPOVTYZGGYDIJ-UHFFFAOYSA-N 0.000 description 2
- KPUWHANPEXNPJT-UHFFFAOYSA-N disiloxane Chemical class [SiH3]O[SiH3] KPUWHANPEXNPJT-UHFFFAOYSA-N 0.000 description 2
- LQZZUXJYWNFBMV-UHFFFAOYSA-N dodecan-1-ol Chemical compound CCCCCCCCCCCCO LQZZUXJYWNFBMV-UHFFFAOYSA-N 0.000 description 2
- 125000003438 dodecyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 2
- QYDYPVFESGNLHU-UHFFFAOYSA-N elaidic acid methyl ester Natural products CCCCCCCCC=CCCCCCCCC(=O)OC QYDYPVFESGNLHU-UHFFFAOYSA-N 0.000 description 2
- 239000010776 emu oil Substances 0.000 description 2
- 235000008524 evening primrose extract Nutrition 0.000 description 2
- 239000010475 evening primrose oil Substances 0.000 description 2
- 229940089020 evening primrose oil Drugs 0.000 description 2
- 125000000373 fatty alcohol group Chemical group 0.000 description 2
- 239000012467 final product Substances 0.000 description 2
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 description 2
- 125000003976 glyceryl group Chemical group [H]C([*])([H])C(O[H])([H])C(O[H])([H])[H] 0.000 description 2
- UBHWBODXJBSFLH-UHFFFAOYSA-N hexadecan-1-ol;octadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCO.CCCCCCCCCCCCCCCCCCO UBHWBODXJBSFLH-UHFFFAOYSA-N 0.000 description 2
- 229920006007 hydrogenated polyisobutylene Polymers 0.000 description 2
- VKPSKYDESGTTFR-UHFFFAOYSA-N isododecane Natural products CC(C)(C)CC(C)CC(C)(C)C VKPSKYDESGTTFR-UHFFFAOYSA-N 0.000 description 2
- 229940100554 isononyl isononanoate Drugs 0.000 description 2
- QXJSBBXBKPUZAA-UHFFFAOYSA-N isooleic acid Natural products CCCCCCCC=CCCCCCCCCC(O)=O QXJSBBXBKPUZAA-UHFFFAOYSA-N 0.000 description 2
- XUGNVMKQXJXZCD-UHFFFAOYSA-N isopropyl palmitate Chemical compound CCCCCCCCCCCCCCCC(=O)OC(C)C XUGNVMKQXJXZCD-UHFFFAOYSA-N 0.000 description 2
- 235000020778 linoleic acid Nutrition 0.000 description 2
- OYHQOLUKZRVURQ-IXWMQOLASA-N linoleic acid Natural products CCCCC\C=C/C\C=C\CCCCCCCC(O)=O OYHQOLUKZRVURQ-IXWMQOLASA-N 0.000 description 2
- 239000010487 meadowfoam seed oil Substances 0.000 description 2
- QYDYPVFESGNLHU-KHPPLWFESA-N methyl oleate Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OC QYDYPVFESGNLHU-KHPPLWFESA-N 0.000 description 2
- 229940073769 methyl oleate Drugs 0.000 description 2
- 239000004200 microcrystalline wax Substances 0.000 description 2
- 235000019808 microcrystalline wax Nutrition 0.000 description 2
- JXTPJDDICSTXJX-UHFFFAOYSA-N n-Triacontane Natural products CCCCCCCCCCCCCCCCCCCCCCCCCCCCCC JXTPJDDICSTXJX-UHFFFAOYSA-N 0.000 description 2
- GOQYKNQRPGWPLP-UHFFFAOYSA-N n-heptadecyl alcohol Natural products CCCCCCCCCCCCCCCCCO GOQYKNQRPGWPLP-UHFFFAOYSA-N 0.000 description 2
- SLCVBVWXLSEKPL-UHFFFAOYSA-N neopentyl glycol Chemical compound OCC(C)(C)CO SLCVBVWXLSEKPL-UHFFFAOYSA-N 0.000 description 2
- 238000006386 neutralization reaction Methods 0.000 description 2
- 239000010466 nut oil Substances 0.000 description 2
- CCCMONHAUSKTEQ-UHFFFAOYSA-N octadecene Natural products CCCCCCCCCCCCCCCCC=C CCCMONHAUSKTEQ-UHFFFAOYSA-N 0.000 description 2
- WWZKQHOCKIZLMA-UHFFFAOYSA-N octanoic acid Chemical compound CCCCCCCC(O)=O WWZKQHOCKIZLMA-UHFFFAOYSA-N 0.000 description 2
- 125000002347 octyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 2
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 description 2
- 235000021313 oleic acid Nutrition 0.000 description 2
- BARWIPMJPCRCTP-UHFFFAOYSA-N oleic acid oleyl ester Natural products CCCCCCCCC=CCCCCCCCCOC(=O)CCCCCCCC=CCCCCCCCC BARWIPMJPCRCTP-UHFFFAOYSA-N 0.000 description 2
- 229940055577 oleyl alcohol Drugs 0.000 description 2
- XMLQWXUVTXCDDL-UHFFFAOYSA-N oleyl alcohol Natural products CCCCCCC=CCCCCCCCCCCO XMLQWXUVTXCDDL-UHFFFAOYSA-N 0.000 description 2
- BARWIPMJPCRCTP-CLFAGFIQSA-N oleyl oleate Chemical compound CCCCCCCC\C=C/CCCCCCCCOC(=O)CCCCCCC\C=C/CCCCCCCC BARWIPMJPCRCTP-CLFAGFIQSA-N 0.000 description 2
- 239000004006 olive oil Substances 0.000 description 2
- 235000008390 olive oil Nutrition 0.000 description 2
- 235000019865 palm kernel oil Nutrition 0.000 description 2
- 239000003346 palm kernel oil Substances 0.000 description 2
- 239000012188 paraffin wax Substances 0.000 description 2
- 229940066842 petrolatum Drugs 0.000 description 2
- 235000019271 petrolatum Nutrition 0.000 description 2
- 229940057874 phenyl trimethicone Drugs 0.000 description 2
- 239000002244 precipitate Substances 0.000 description 2
- 230000002035 prolonged effect Effects 0.000 description 2
- QELSKZZBTMNZEB-UHFFFAOYSA-N propylparaben Chemical compound CCCOC(=O)C1=CC=C(O)C=C1 QELSKZZBTMNZEB-UHFFFAOYSA-N 0.000 description 2
- 239000010667 rosehip oil Substances 0.000 description 2
- 239000003813 safflower oil Substances 0.000 description 2
- 230000035483 skin reaction Effects 0.000 description 2
- 231100000430 skin reaction Toxicity 0.000 description 2
- WXMKPNITSTVMEF-UHFFFAOYSA-M sodium benzoate Chemical compound [Na+].[O-]C(=O)C1=CC=CC=C1 WXMKPNITSTVMEF-UHFFFAOYSA-M 0.000 description 2
- 235000010234 sodium benzoate Nutrition 0.000 description 2
- 239000004299 sodium benzoate Substances 0.000 description 2
- GEHJYWRUCIMESM-UHFFFAOYSA-L sodium sulfite Chemical compound [Na+].[Na+].[O-]S([O-])=O GEHJYWRUCIMESM-UHFFFAOYSA-L 0.000 description 2
- 239000003549 soybean oil Substances 0.000 description 2
- 235000012424 soybean oil Nutrition 0.000 description 2
- 229940032094 squalane Drugs 0.000 description 2
- 125000004079 stearyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 2
- 238000003786 synthesis reaction Methods 0.000 description 2
- 238000010998 test method Methods 0.000 description 2
- TUNFSRHWOTWDNC-HKGQFRNVSA-N tetradecanoic acid Chemical compound CCCCCCCCCCCCC[14C](O)=O TUNFSRHWOTWDNC-HKGQFRNVSA-N 0.000 description 2
- UWHZIFQPPBDJPM-BQYQJAHWSA-N trans-vaccenic acid Chemical compound CCCCCC\C=C\CCCCCCCCCC(O)=O UWHZIFQPPBDJPM-BQYQJAHWSA-N 0.000 description 2
- LADGBHLMCUINGV-UHFFFAOYSA-N tricaprin Chemical compound CCCCCCCCCC(=O)OCC(OC(=O)CCCCCCCCC)COC(=O)CCCCCCCCC LADGBHLMCUINGV-UHFFFAOYSA-N 0.000 description 2
- UUJLHYCIMQOUKC-UHFFFAOYSA-N trimethyl-[oxo(trimethylsilylperoxy)silyl]peroxysilane Chemical compound C[Si](C)(C)OO[Si](=O)OO[Si](C)(C)C UUJLHYCIMQOUKC-UHFFFAOYSA-N 0.000 description 2
- LINXHFKHZLOLEI-UHFFFAOYSA-N trimethyl-[phenyl-bis(trimethylsilyloxy)silyl]oxysilane Chemical compound C[Si](C)(C)O[Si](O[Si](C)(C)C)(O[Si](C)(C)C)C1=CC=CC=C1 LINXHFKHZLOLEI-UHFFFAOYSA-N 0.000 description 2
- 235000019871 vegetable fat Nutrition 0.000 description 2
- 239000010497 wheat germ oil Substances 0.000 description 2
- 239000001628 zingiber officinale rosc. oil terpeneless Substances 0.000 description 2
- JNAYPSWVMNJOPQ-UHFFFAOYSA-N 2,3-bis(16-methylheptadecanoyloxy)propyl 16-methylheptadecanoate Chemical compound CC(C)CCCCCCCCCCCCCCC(=O)OCC(OC(=O)CCCCCCCCCCCCCCC(C)C)COC(=O)CCCCCCCCCCCCCCC(C)C JNAYPSWVMNJOPQ-UHFFFAOYSA-N 0.000 description 1
- CHHHXKFHOYLYRE-UHFFFAOYSA-M 2,4-Hexadienoic acid, potassium salt (1:1), (2E,4E)- Chemical compound [K+].CC=CC=CC([O-])=O CHHHXKFHOYLYRE-UHFFFAOYSA-M 0.000 description 1
- IKOKHHBZFDFMJW-UHFFFAOYSA-N 2-[4-[2-(2,3-dihydro-1H-inden-2-ylamino)pyrimidin-5-yl]-3-(2-morpholin-4-ylethoxy)pyrazol-1-yl]-1-(2,4,6,7-tetrahydrotriazolo[4,5-c]pyridin-5-yl)ethanone Chemical compound C1C(CC2=CC=CC=C12)NC1=NC=C(C=N1)C=1C(=NN(C=1)CC(=O)N1CC2=C(CC1)NN=N2)OCCN1CCOCC1 IKOKHHBZFDFMJW-UHFFFAOYSA-N 0.000 description 1
- VXZBYIWNGKSFOJ-UHFFFAOYSA-N 2-[4-[5-(2,3-dihydro-1H-inden-2-ylamino)pyrazin-2-yl]pyrazol-1-yl]-1-(2,4,6,7-tetrahydrotriazolo[4,5-c]pyridin-5-yl)ethanone Chemical compound C1C(CC2=CC=CC=C12)NC=1N=CC(=NC=1)C=1C=NN(C=1)CC(=O)N1CC2=C(CC1)NN=N2 VXZBYIWNGKSFOJ-UHFFFAOYSA-N 0.000 description 1
- TWJNQYPJQDRXPH-UHFFFAOYSA-N 2-cyanobenzohydrazide Chemical compound NNC(=O)C1=CC=CC=C1C#N TWJNQYPJQDRXPH-UHFFFAOYSA-N 0.000 description 1
- CYDQOEWLBCCFJZ-UHFFFAOYSA-N 4-(4-fluorophenyl)oxane-4-carboxylic acid Chemical compound C=1C=C(F)C=CC=1C1(C(=O)O)CCOCC1 CYDQOEWLBCCFJZ-UHFFFAOYSA-N 0.000 description 1
- 238000012935 Averaging Methods 0.000 description 1
- 229910052582 BN Inorganic materials 0.000 description 1
- PZNSFCLAULLKQX-UHFFFAOYSA-N Boron nitride Chemical compound N#B PZNSFCLAULLKQX-UHFFFAOYSA-N 0.000 description 1
- 201000004624 Dermatitis Diseases 0.000 description 1
- 239000003109 Disodium ethylene diamine tetraacetate Substances 0.000 description 1
- ZGTMUACCHSMWAC-UHFFFAOYSA-L EDTA disodium salt (anhydrous) Chemical compound [Na+].[Na+].OC(=O)CN(CC([O-])=O)CCN(CC(O)=O)CC([O-])=O ZGTMUACCHSMWAC-UHFFFAOYSA-L 0.000 description 1
- 206010015150 Erythema Diseases 0.000 description 1
- SHBUUTHKGIVMJT-UHFFFAOYSA-N Hydroxystearate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OO SHBUUTHKGIVMJT-UHFFFAOYSA-N 0.000 description 1
- CERQOIWHTDAKMF-UHFFFAOYSA-N Methacrylic acid Chemical compound CC(=C)C(O)=O CERQOIWHTDAKMF-UHFFFAOYSA-N 0.000 description 1
- 235000021360 Myristic acid Nutrition 0.000 description 1
- TUNFSRHWOTWDNC-UHFFFAOYSA-N Myristic acid Natural products CCCCCCCCCCCCCC(O)=O TUNFSRHWOTWDNC-UHFFFAOYSA-N 0.000 description 1
- 235000008331 Pinus X rigitaeda Nutrition 0.000 description 1
- 235000011613 Pinus brutia Nutrition 0.000 description 1
- 241000018646 Pinus brutia Species 0.000 description 1
- 229920003171 Poly (ethylene oxide) Polymers 0.000 description 1
- 235000009470 Theobroma cacao Nutrition 0.000 description 1
- 244000299461 Theobroma cacao Species 0.000 description 1
- XKMYWNHZAQUEPY-YZGJEOKZSA-N [(3s,8s,9s,10r,13r,14s,17r)-10,13-dimethyl-17-[(2r)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1h-cyclopenta[a]phenanthren-3-yl] 12-hydroxyoctadecanoate Chemical compound C([C@@H]12)C[C@]3(C)[C@@H]([C@H](C)CCCC(C)C)CC[C@H]3[C@@H]1CC=C1[C@]2(C)CC[C@H](OC(=O)CCCCCCCCCCC(O)CCCCCC)C1 XKMYWNHZAQUEPY-YZGJEOKZSA-N 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- PNEYBMLMFCGWSK-UHFFFAOYSA-N aluminium oxide Inorganic materials [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 description 1
- IRERQBUNZFJFGC-UHFFFAOYSA-L azure blue Chemical compound [Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Al+3].[Al+3].[Al+3].[Al+3].[Al+3].[Al+3].[S-]S[S-].[O-][Si]([O-])([O-])[O-].[O-][Si]([O-])([O-])[O-].[O-][Si]([O-])([O-])[O-].[O-][Si]([O-])([O-])[O-].[O-][Si]([O-])([O-])[O-].[O-][Si]([O-])([O-])[O-] IRERQBUNZFJFGC-UHFFFAOYSA-L 0.000 description 1
- 238000005452 bending Methods 0.000 description 1
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 description 1
- 150000001558 benzoic acid derivatives Chemical class 0.000 description 1
- 235000014121 butter Nutrition 0.000 description 1
- 229910000019 calcium carbonate Inorganic materials 0.000 description 1
- 239000006229 carbon black Substances 0.000 description 1
- 229940085262 cetyl dimethicone Drugs 0.000 description 1
- 239000013043 chemical agent Substances 0.000 description 1
- 235000012000 cholesterol Nutrition 0.000 description 1
- 229940072104 cholesteryl hydroxystearate Drugs 0.000 description 1
- 229920006037 cross link polymer Polymers 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 230000032798 delamination Effects 0.000 description 1
- 229940008099 dimethicone Drugs 0.000 description 1
- FPAFDBFIGPHWGO-UHFFFAOYSA-N dioxosilane;oxomagnesium;hydrate Chemical compound O.[Mg]=O.[Mg]=O.[Mg]=O.O=[Si]=O.O=[Si]=O.O=[Si]=O.O=[Si]=O FPAFDBFIGPHWGO-UHFFFAOYSA-N 0.000 description 1
- 235000019301 disodium ethylene diamine tetraacetate Nutrition 0.000 description 1
- 230000009977 dual effect Effects 0.000 description 1
- 230000001804 emulsifying effect Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 210000002615 epidermis Anatomy 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 210000003414 extremity Anatomy 0.000 description 1
- 239000010419 fine particle Substances 0.000 description 1
- 230000003803 hair density Effects 0.000 description 1
- 210000003780 hair follicle Anatomy 0.000 description 1
- 230000003779 hair growth Effects 0.000 description 1
- 230000003660 hair regeneration Effects 0.000 description 1
- 229940072106 hydroxystearate Drugs 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- UQSXHKLRYXJYBZ-UHFFFAOYSA-N iron oxide Inorganic materials [Fe]=O UQSXHKLRYXJYBZ-UHFFFAOYSA-N 0.000 description 1
- 239000010445 mica Substances 0.000 description 1
- 229910052618 mica group Inorganic materials 0.000 description 1
- 235000013336 milk Nutrition 0.000 description 1
- 239000008267 milk Substances 0.000 description 1
- 210000004080 milk Anatomy 0.000 description 1
- 230000004792 oxidative damage Effects 0.000 description 1
- NDLPOXTZKUMGOV-UHFFFAOYSA-N oxo(oxoferriooxy)iron hydrate Chemical compound O.O=[Fe]O[Fe]=O NDLPOXTZKUMGOV-UHFFFAOYSA-N 0.000 description 1
- 125000000913 palmityl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 238000011056 performance test Methods 0.000 description 1
- 229920003217 poly(methylsilsesquioxane) Polymers 0.000 description 1
- 235000010241 potassium sorbate Nutrition 0.000 description 1
- 239000004302 potassium sorbate Substances 0.000 description 1
- 229940069338 potassium sorbate Drugs 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 239000004405 propyl p-hydroxybenzoate Substances 0.000 description 1
- 235000010232 propyl p-hydroxybenzoate Nutrition 0.000 description 1
- 229960003415 propylparaben Drugs 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 238000007790 scraping Methods 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- 229960003885 sodium benzoate Drugs 0.000 description 1
- HRZFUMHJMZEROT-UHFFFAOYSA-L sodium disulfite Chemical compound [Na+].[Na+].[O-]S(=O)S([O-])(=O)=O HRZFUMHJMZEROT-UHFFFAOYSA-L 0.000 description 1
- 239000001540 sodium lactate Substances 0.000 description 1
- 235000011088 sodium lactate Nutrition 0.000 description 1
- 229940005581 sodium lactate Drugs 0.000 description 1
- 229940001584 sodium metabisulfite Drugs 0.000 description 1
- 235000010262 sodium metabisulphite Nutrition 0.000 description 1
- 235000010265 sodium sulphite Nutrition 0.000 description 1
- AKHNMLFCWUSKQB-UHFFFAOYSA-L sodium thiosulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=S AKHNMLFCWUSKQB-UHFFFAOYSA-L 0.000 description 1
- 235000019345 sodium thiosulphate Nutrition 0.000 description 1
- 238000013112 stability test Methods 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 230000002194 synthesizing effect Effects 0.000 description 1
- 229940071127 thioglycolate Drugs 0.000 description 1
- 125000003396 thiol group Chemical group [H]S* 0.000 description 1
- 239000004408 titanium dioxide Substances 0.000 description 1
- 238000004383 yellowing Methods 0.000 description 1
- 239000011787 zinc oxide Substances 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/20—Halogens; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/23—Sulfur; Selenium; Tellurium; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/46—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q9/00—Preparations for removing hair or for aiding hair removal
- A61Q9/04—Depilatories
Abstract
The invention relates to the technical field of depilation, in particular to the field of IPC A61K8, and more particularly relates to pre-dispersed calcium ions and a single-component ceramic coating prepared from the same. The preparation raw materials of the pre-dispersed calcium ions comprise: 1-60 parts of calcium ion raw material, 0-5 parts of first thickening stabilizer, 1-10 parts of first emulsifier, 0-20 parts of first grease and 10-70 parts of first aqueous component. The depilatory product produced by using thioglycollic acid and pre-dispersed calcium ions is economic, low in cost, high in cost performance and long in shelf life, and can ensure that the production of domestic depilatory product manufacturers is not influenced by foreign raw material suppliers and sales; meanwhile, compared with a calcium thioglycollate process, the intermediate links are omitted, the formula cost can be greatly reduced, and the depilatory product prepared by adopting the thioglycollate and pre-dispersed calcium ions has higher cost performance.
Description
Technical Field
The invention relates to the technical field of depilation, in particular to the field of IPC A61K8, and more particularly relates to pre-dispersed calcium ions and a single-component ceramic coating prepared from the same.
Background
Chemical depilation is a method for removing hairs after dissolving the hairs by utilizing the chemical action of a chemical depilatory and the keratin, because partial hair roots under the epidermis can also be dissolved by the chemical depilatory, the hair regeneration speed is slower than that of a scraping method, the effect can last for more than 2 weeks, and the chemical depilation method has the advantages that: simple and rapid, and relatively low cost.
Chemical depilation uses a chemical agent which dissolves the structure of the hair, penetrates into the hair follicle within a few minutes, softens and breaks the keratin molecular chains constituting the hair, removes the inelegant body hair at the body parts such as the armpit, and has the dual effects of depilation and skin care. The main component of the preparation is thioglycolic acid (calcium), and the preparation is suitable for people who are afraid of pain but have low possibility of skin allergy.
A common chemical depilatory product today uses calcium thioglycolate, which is used to reduce irritation. Calcium thioglycolate, namely calcium thioglycolate, white crystalline powder, is insoluble in water, slightly soluble in alcohol and has special smell of sulfhydryl compounds, and the calcium thioglycolate can destroy disulfide bonds in hair protein to achieve the aim of lightening or dissolving hair, thereby achieving the hair removal effect. The pH value of the system, the amount of calcium thioglycolate and the dispersion state influence the depilation effect. Because calcium thioglycolate is insoluble in water and grease, calcium thioglycolate particles are larger after powdery calcium thioglycolate is added into a depilatory formula and dispersed, the depilatory effect is influenced, and the appearance of the paste is not fine enough.
Calcium thioglycolate is an acid-base neutralization process in the synthesis process, and high temperature in the process can cause partial sulfydryl to be oxidized and damaged, reduce the hair removal effect of a final product and easily cause yellowing of the product. Meanwhile, the existence of calcium thioglycolate in larger particles can also reduce the depilatory effect and lead to insufficient brightness of the paste.
Calcium thioglycolate is generally insoluble in water and grease, so the particle size of calcium thioglycolate added into a depilation system is the dispersed particle size of thioglycolic acid in the final product, the dispersed particle size of calcium thioglycolate can influence depilation efficiency, and the smaller the particle, the more uniform the system and the higher the depilation efficiency.
Patent document CN112156039A discloses a depilatory preparation and a preparation method thereof, wherein myristic acid and pine needle extract are added to obtain the depilatory preparation, which has a significant hair growth inhibition effect, but the particle size and dispersion degree of calcium thioglycolate in the system are not significantly improved.
Patent document CN109303704A discloses a depilatory cream, which can improve the depilatory experience of consumers by adding diatomite to adsorb the taste of calcium thioglycolate, but does not significantly improve the particle size and dispersion degree of calcium thioglycolate in the system.
Disclosure of Invention
In order to solve the problems, the invention provides a pre-dispersed calcium ion which comprises, by weight, 1-60 parts of calcium ion raw materials, 0-5 parts of thickening stabilizing agents, 1-10 parts of emulsifying agents, 0-20 parts of grease and 10-70 parts of water-based components.
Preferably, the calcium ion raw material comprises one or more of calcium hydroxide, calcium oxide, calcium sulfate, calcium chloride and calcium citrate.
Preferably, the thickening stabilizer comprises one or more of hydroxyethyl cellulose, methyl hydroxyethyl cellulose, cross-linked carboxymethyl cellulose, hydroxypropyl methyl cellulose stearyloxy ether, hydroxypropyl cellulose, hydroxyethyl ethyl cellulose, carboxymethyl hydroxyethyl cellulose, cellulose gum, ethyl cellulose, xanthan gum, gellan gum, gelatin, hydroxypropyl guar gum, carbomer, magnesium aluminum silicate, sodium alginate, polyvinyl alcohol, polyethylene oxide.
Preferably, the emulsifier comprises one or more of fatty alcohol-polyoxyethylene ether, fatty alcohol, fatty acid, alkylphenol ethoxylates, ethoxylated lanolin, ethoxylated siloxane, polyethylene glycol fatty acid ester, C20-40 alkanol polyether-10, alkyl glycoside, fatty acid monoglyceride, phosphate monoester and diester, and salts thereof.
Preferably, the fatty alcohol comprises one or more of cetearyl alcohol, decyl alcohol, capryl alcohol, lauryl alcohol, myristyl alcohol, capryl decyl alcohol, palmityl alcohol, stearyl alcohol, lauryl/myristyl alcohol, oleyl alcohol.
Preferably, the fatty acid comprises one or more of palmitoleic acid, lauric acid, myristic acid, oleic acid, stearic acid, arachidic acid, vaccenic acid, linoleic acid.
Preferably, the grease comprises one or more of hydrocarbon oil, synthetic grease and animal and vegetable oil.
Preferably, the hydrocarbon oil comprises one or more of mineral oil, petrolatum, C15-19 alkanes, hydrogenated polydecene, isohexadecane, polyethylene, hydrogenated polyisobutene, paraffin, isododecane, isohexadecane, isomeric eicosane, squalane, ceresin, microcrystalline wax, octadecene.
Preferably, the synthetic oil or fat includes one or more of silicone oil, glyceryl stearate, propylheptyl caprylate, polyhydroxystearic acid, isopropyl myristate, isopropyl palmitate, neopentyl glycol di (ethylhexanoate), isooctyl palmitate, methyl oleate, isooctyl oleate, decyl oleate, oleyl oleate, isononyl isononanoate, C12-C15 benzoate, glyceryl hydroxystearate, cholesteryl hydroxystearate, dioctyl carbonate, isotridecyl isononanoate, bisethylhexyl carbonate, pentaerythritol distearate, diisostearyl malate, caprylic/capric triglyceride, glyceryl tri (ethylhexanoate), triglycerol cocoate, triglycerol triisostearate, triisopolyglyceryl stearate, pentaerythritol tetrakis (2-ethylhexanoate), pentaerythritol tetraisostearate.
Preferably, the animal or vegetable fat includes one or more of lanolin, emu oil, horse fat, borage seed oil, kiwi seed oil, ginger root oil, soybean oil, safflower seed oil, olive oil, fruit fat oil, castor oil, evening primrose oil, rose hip oil, avocado oil, jojoba oil, grapeseed oil, meadowfoam seed oil, shea butter, cocoa butter, macadamia nut oil, camellia seed oil, palm kernel oil, camellia seed oil, rosa canina fruit oil, camellia seed oil, MORINGA OLEIFERA (MORINGA OLEIFERA) seed oil, latani oil, wheat germ oil, sweet almond oil, hydrogenated coconut oil, hydrogenated jojoba oil, hydrogenated shea butter oil, hydrogenated cocoa butter, hydrogenated mango butter, hydrogenated grape seed oil.
Preferably, the silicone oil comprises one or more of cyclopentadimethylsiloxane, trimethylsiloxysilicate, polydimethylsiloxane, dimethiconol, phenyl trimethicone, cetyl polydimethylsiloxane, octyl polydimethylsiloxane, stearyl polydimethylsiloxane.
Preferably, the aqueous component comprises one or more of water, propylene glycol, glycerol, sorbitol, butylene glycol, pentylene glycol, hexylene glycol, octylene glycol, ethanol, phenoxyethanol.
The applicant has unexpectedly found that by selecting specific raw materials to prepare pre-dispersed calcium ions, the fineness of the paste of the prepared depilatory product and the depilatory effect can be improved. The method is probably because the dispersion uniformity of calcium ions in a system can be increased after raw materials containing calcium ions are uniformly mixed in a specific system, and then pre-dispersed calcium ions with high dispersion uniformity are applied to a depilatory product and can react with thioglycolic acid to generate colloidal calcium thioglycolate precipitate, and the calcium thioglycolate precipitate synthesized by the pre-dispersed calcium ions with high dispersion uniformity has fine particles and is uniformly distributed, so that the prepared paste has high fineness, the depilatory effect of the depilatory product prepared can be effectively improved, and the problems that the final depilatory product is large in dispersed particles and the depilatory efficiency is influenced due to the fact that the thioglycolic acid is insoluble in a water phase and an oil phase are solved.
The invention provides a pre-dispersing method for pre-dispersing calcium ions in a second aspect, which comprises the following steps:
s1, adding a calcium ion raw material into an aqueous component, mixing, stirring and dispersing until no agglomeration exists;
s2, under the stirring condition, adding the thickening stabilizer, and stirring and dispersing until no obvious particles exist;
and S3, adding the emulsifier and the grease, and stirring and dispersing uniformly.
The applicant has unexpectedly found that pre-dispersed calcium ions are prepared by emulsifying and dispersing calcium ion raw materials in a specific system in advance, and the pre-dispersed calcium ions are applied to depilatory products containing specific grease, emulsifier, thickening stability and other raw materials, so that the stability of the depilatory products in the preparation process can be improved. The reason is probably that in the production process of the depilatory product, thioglycolic acid and pre-dispersed calcium ions react to generate calcium thioglycolate, so that the acid-base concentration during acid-base neutralization can be effectively reduced, and the damage of the thioglycolic acid is reduced, so that the stability in the preparation process is improved, and by adopting the production mode, the oxidative damage of a calcium thioglycolate raw material in the synthesis and storage processes can be reduced, the shelf life of the depilatory product is prolonged, and generally 3-6 months can be prolonged.
The invention provides the application of the pre-dispersed calcium ions in the depilatory product, wherein the depilatory product comprises a phase A, a phase B and a phase C in parts by weight;
preferably, the phase a comprises: 0-3 parts of thickening stabilizer, 1-50 parts of pre-dispersed calcium ions, 35-90 parts of aqueous component, 2-5 parts of potassium hydroxide and 0-1 part of antioxidant;
preferably, the phase B comprises: 0.1-5 parts of thioglycolic acid, 2-10 parts of emulsifier, 0-30 parts of grease, 0-3 parts of filler and 0-2 parts of chelating agent;
preferably, the phase C comprises: 0.1-1.0 part of essence and 0-1 part of preservative.
Preferably, the weight ratio of the thioglycolic acid to the pre-dispersed calcium ions is 1: (0.5-5).
The applicant has surprisingly found that by controlling the weight ratio of thioglycolic acid to predispersed calcium ions, the irritation and epilation efficiency of the epilation product can be adjusted, thereby meeting the needs of the vast majority of the population. This is probably due to the fact that in the art, the higher ratio by weight of calcium ion/thioglycolic acid in thioglycolic acid based depilatory products, the irritation of the depilatory product is reduced and the depilatory speed is slowed; with a low weight ratio of calcium ions/thioglycolic acid, the irritation of the epilation product will increase, while the epilation speed will be faster. In the practical application process, the hair of the western people is vigorous, and the hair removal is difficult, so a hair removal product with a low weight ratio of calcium ions to thioglycollic acid is needed, while the hair of the oriental people is sparse, the skin is fine and smooth, so the weight ratio of the calcium ions to the thioglycollic acid in the hair removal product needs to be higher. The traditional method for preparing the depilatory product by using calcium thioglycolate fixes the ratio of calcium to thioglycolate, so that the irritation and the depilatory efficiency of the depilatory product cannot be adjusted and balanced, and one product cannot meet the requirements of most people. The application prepares pre-dispersed calcium ions firstly, and then the pre-dispersed calcium ions are mixed with thioglycolic acid to react to prepare the unhairing product, so that the problem of the requirements of different crowds is effectively solved, the weight ratio of the thioglycolic acid to the pre-dispersed calcium ions can be flexibly adjusted according to different requirements, the formula is flexible and flexible, and different requirements of different world races in east and west can be met.
Preferably, the antioxidant comprises sodium bisulfite, sodium sulfite, sodium metabisulfite, sodium thiosulfate.
Preferably, the thickening stabilizer comprises one or more of hydroxyethyl cellulose, methyl hydroxyethyl cellulose, cross-linked carboxymethyl cellulose, hydroxypropyl methyl cellulose stearyloxy ether, hydroxypropyl cellulose, hydroxyethyl ethyl cellulose, carboxymethyl hydroxyethyl cellulose, cellulose gum, ethyl cellulose, xanthan gum, gellan gum, gelatin, hydroxypropyl guar gum, carbomer, magnesium aluminum silicate, sodium alginate, polyvinyl alcohol, oxidized polyethylene.
Preferably, the emulsifier comprises one or more of fatty alcohol-polyoxyethylene ether, fatty alcohol, fatty acid, alkylphenol ethoxylates, ethoxylated lanolin, ethoxylated siloxane, polyethylene glycol fatty acid ester, C20-40 alkanol polyether-10, alkyl glycoside, fatty acid monoglyceride, phosphate monoester and diester, and salts thereof.
Preferably, the fatty alcohol comprises one or more of cetearyl alcohol, decyl alcohol, capryl alcohol, lauryl alcohol, myristyl alcohol, capryl decyl alcohol, palmityl alcohol, stearyl alcohol, lauryl/myristyl alcohol, oleyl alcohol.
Preferably, the fatty acid comprises one or more of palmitoleic acid, lauric acid, myristic acid, oleic acid, stearic acid, arachidic acid, vaccenic acid, linoleic acid.
Preferably, the grease comprises one or more of hydrocarbon oil, synthetic grease and animal and vegetable oil.
Preferably, the hydrocarbon oil comprises one or more of mineral oil, petrolatum, C15-19 alkanes, hydrogenated polydecene, isohexadecane, polyethylene, hydrogenated polyisobutene, paraffin, isododecane, isohexadecane, isomeric eicosane, ceresin, microcrystalline wax, octadecene.
Preferably, the synthetic oil includes one or more of silicone oil, glyceryl stearate, propylheptyl caprylate, polyhydroxystearic acid, isopropyl myristate, isopropyl palmitate, neopentyl glycol di (ethylhexanoate), isooctyl palmitate, methyl oleate, isooctyl oleate, decyl oleate, oleyl oleate, isononyl isononanoate, C12-C15 benzoates, glyceryl hydroxystearate, cholesterol hydroxystearate, dioctyl carbonate, isotridecyl isononanoate, bisethylhexyl carbonate, pentaerythritol distearate, diisostearyl malate, caprylic/capric triglyceride, glyceryl tri (ethylhexanoate), triglycerol cocoate, glyceryl triisostearate, polyglyceryl triisostearate, pentaerythritol tetrakis (2-ethylhexanoate), pentaerythritol tetraisostearate.
Preferably, the animal or vegetable fat includes one or more of squalane, lanolin, emu oil, horse fat, borage seed oil, kiwi seed oil, ginger root oil, soybean oil, safflower seed oil, olive oil, fruit fat oil, castor oil, evening primrose oil, rose hip oil, avocado oil, jojoba oil, grape seed oil, meadowfoam seed oil, shea butter, cocoa seed fat, macadamia nut oil, camellia seed oil, palm kernel oil, camellia seed oil, rosa canina fruit oil, camellia seed oil, MORINGA OLEIFERA (MORINGA OLEIFERA) seed oil, latani oil, wheat germ oil, sweet almond oil, hydrogenated coconut oil, hydrogenated jojoba oil, hydrogenated fruit tree fruit fat oil, hydrogenated cocoa butter, hydrogenated mango fat, hydrogenated grape seed oil.
Preferably, the silicone oil comprises one or more of cyclopentadimethylsiloxane, trimethylsiloxysilicate, polydimethylsiloxane, dimethiconol, phenyl trimethicone, cetyl dimethicone, octyl methicone, stearyl dimethicone.
Preferably, the aqueous component comprises one or more of water, propylene glycol, glycerol, sorbitol, butylene glycol, pentylene glycol, hexylene glycol, octylene glycol, ethanol, phenoxyethanol.
Preferably, the filler comprises one or more of titanium dioxide, zinc oxide, ferric oxide, mica, ultramarine, carbon black, chrome green, talcum powder, diatomite, silica, boron nitride, alumina, stearic acid, polyhydroxystearic acid, polymethylsilsesquioxane, methacrylic acid cross-linked polymer and calcium carbonate.
Preferably, the chelating agent comprises disodium EDTA, DTPA-5Na.
Preferably, the preservative comprises sodium benzoate, potassium sorbate, sodium lactate, propyl paraben.
Preferably, the method of preparing the depilatory product comprises the steps of: and uniformly mixing all the components of the phase A, adding the component of the phase B, uniformly mixing, and adding the component C to obtain the composition.
Further preferably, the preparation method of the depilatory product specifically comprises the following steps:
a1, uniformly stirring and dispersing a thickening stabilizer in an aqueous component, adding pre-dispersed calcium ions and an antioxidant, uniformly stirring, and heating to 60-80 ℃;
a2, adding potassium hydroxide under stirring, keeping the temperature of the system at 85-90 ℃, and continuously stirring and dispersing uniformly to obtain a mixed phase A;
a3, sequentially adding thioglycollic acid, grease, an emulsifier, a filling agent and a chelating agent into the mixed phase A in the step A2, stirring, cooling to 60-80 ℃, and homogenizing for 1-10min to obtain a solution I;
and A4, stirring the solution I, continuously cooling to 40-50 ℃, adding the phase C, uniformly stirring, cooling to room temperature, and discharging.
Has the advantages that:
1. according to the invention, the pre-dispersed calcium ions are prepared by selecting specific raw materials, so that the fineness of the paste of the prepared depilatory product and the depilatory effect can be improved.
2. The calcium ion raw material is emulsified and dispersed in a specific system in advance to prepare the pre-dispersed calcium ions, and the pre-dispersed calcium ions are applied to the depilating product containing the raw materials such as specific grease, emulsifier, thickening stability and the like, so that the stability of the depilating product in the preparation process can be improved.
3. The invention can adjust the irritation and the depilation efficiency of the depilation product by controlling the weight ratio of the thioglycolic acid to the pre-dispersed calcium ions, thereby meeting the requirements of most people.
4. The method for producing depilatory products by using thioglycolic acid and pre-dispersed calcium ions is economic, low in cost, high in cost performance and long in shelf life of the products, and can ensure that the production of domestic depilatory products is not influenced by foreign raw material suppliers and sales; meanwhile, compared with a calcium thioglycollate process, the intermediate links are omitted, the formula cost can be greatly reduced, and the depilatory product prepared by adopting the thioglycollate and pre-dispersed calcium ions has higher cost performance.
5. The process for synthesizing the calcium thioglycolate in the process of producing the depilatory product by using the thioglycolic acid and the pre-dispersed calcium ions fills the domestic blank, and has larger technical and market effects.
Drawings
FIG. 1 is a photograph of a depilatory product prepared in example 1 under a 640-fold microscope;
FIG. 2 is a photograph of the epilatory product prepared in comparative example 1 at 640 times microscope;
FIG. 3 is a graph comparing the irritation and depilating time of the depilatory products prepared in examples 3-5;
FIG. 4 is a graph comparing the irritation and depilating time of the depilatory products prepared in examples 1, 6-7;
FIG. 5 is a graph comparing the irritation and depilating time of the depilatory products prepared in examples 8-10.
Detailed Description
Examples
Example 1
The calcium ion raw material is calcium oxide.
The thickening stabilizer is hydroxyethyl cellulose.
The hydroxyethylcellulose was purchased from HHR250 hydroxyethylcellulose produced by Hish (China) investment Limited.
The emulsifier is fatty alcohol and C20-40 alkanol polyether-10.
The fatty alcohol is cetostearyl alcohol.
The weight ratio of the fatty alcohol to the C20-40 alkanol polyether-10 is 3.
The CAS number of cetostearyl alcohol is 67762-27-0.
The C20-40 alkanol polyether-10 was purchased from Hangzhou Fuda Fine oils, inc.
The oil is hydrocarbon oil or synthetic oil.
The hydrocarbon oil is mineral oil.
The mineral oil was purchased from south Tongdeli chemical Co.
The synthetic grease is glycerol stearate.
The CAS number of the glyceryl stearate is 85666-92-8.
The weight ratio of the hydrocarbon oil to the synthetic grease is 5.
The aqueous component is water.
The invention provides a pre-dispersing method for pre-dispersing calcium ions in a second aspect, which comprises the following steps:
s1, adding a calcium ion raw material into an aqueous component, and mixing, stirring and dispersing until no agglomeration exists;
s2, under the condition of stirring, adding the thickening stabilizer, and stirring and dispersing until no obvious particles exist;
and S3, adding the emulsifier and the grease, and stirring and dispersing uniformly.
The invention provides the application of the pre-dispersed calcium ions in the depilatory product, wherein the depilatory product comprises a phase A, a phase B and a phase C in parts by weight;
the phase A comprises: 0.2 part of thickening stabilizer, 7 parts of pre-dispersed calcium ions, 70.1 parts of aqueous component, 3.4 parts of potassium hydroxide and 0.3 part of antioxidant;
the phase B comprises: 3 parts of thioglycolic acid, 7.5 parts of emulsifier and 8 parts of grease;
the phase C comprises: 0.5 part of essence.
The components of the thickening stabilizer, the emulsifier, the water-based component and the grease are the same as those of the thickening stabilizer, the emulsifier, the water-based component and the grease in the pre-dispersed calcium ions.
The antioxidant is sodium bisulfite.
The essence is bought from flowery essence produced by Jinsu Suteng chemical technology Co., ltd.
The preparation method of the depilatory product specifically comprises the following steps:
a1, uniformly stirring and dispersing a thickening stabilizer in an aqueous component, adding pre-dispersed calcium ions and an antioxidant, uniformly stirring, and heating to 70 ℃;
a2, adding potassium hydroxide under stirring, keeping the temperature of the system at 85 ℃, and continuously stirring and uniformly dispersing to obtain a mixed phase A;
a3, sequentially adding thioglycollic acid, grease and an emulsifier into the mixed phase A in the step A2, stirring, cooling to 70 ℃, and homogenizing for 5min to obtain a first solution;
and A4, stirring the solution I, continuously cooling to 45 ℃, adding the phase C, uniformly stirring, cooling to 25 ℃, and discharging.
Example 2
Example 2 provides the use of said pre-dispersed calcium ions in depilatory products, as described in example 1. The difference lies in that:
the depilatory product comprises a phase A, a phase B and a phase C in parts by weight;
the phase A comprises: 7 parts of pre-dispersed calcium ions, 75.5 parts of water-based component, 5 parts of potassium hydroxide and 0.3 part of antioxidant;
the phase B comprises: 3 parts of thioglycolic acid, 7.5 parts of emulsifier and 1 part of chelating agent;
the phase C comprises: 0.5 part of essence and 0.3 part of preservative.
The components of the emulsifier and the aqueous component are the same as those of the emulsifier and the aqueous component in the pre-dispersed calcium ions.
The antioxidant is sodium bisulfite.
The chelating agent is DTPA-5Na.
The preservative is sodium benzoate.
The essence is purchased from flowery essence produced by Jinan Xin Suteng chemical technology Limited.
The preparation method of the depilatory product specifically comprises the following steps:
a1, uniformly stirring and dispersing pre-dispersed calcium ions and an antioxidant in an aqueous component, and heating to 70 ℃;
a2, adding potassium hydroxide under stirring, keeping the temperature of the system at 85 ℃, and continuously stirring and uniformly dispersing to obtain a mixed phase A;
a3, sequentially adding thioglycollic acid, an emulsifier and a chelating agent into the mixed phase A in the step A2, stirring, cooling to 70 ℃, and homogenizing for 5min to obtain a first solution;
and A4, stirring the solution I, continuously cooling to 45 ℃, adding the phase C, uniformly stirring, cooling to 25 ℃, and discharging.
Example 3
Example 3 provides the use of said pre-dispersed calcium ions in depilatory products, as described in example 1. The difference lies in that:
the depilatory product comprises 4 parts by weight of pre-dispersed calcium ions and 2 parts by weight of thioglycolic acid.
Example 4
Example 4 provides the use of said pre-dispersed calcium ions in depilatory products, as described in example 1. The difference lies in that:
the depilatory product comprises 7 parts by weight of pre-dispersed calcium ions and 2 parts by weight of thioglycolic acid.
Example 5
Example 5 provides the use of said pre-dispersed calcium ions in depilatory products, as described in example 1. The difference lies in that:
the depilatory product is prepared from the raw materials of 10 parts by weight of pre-dispersed calcium ions and 2 parts by weight of thioglycolic acid.
Example 6
Example 6 provides the use of said pre-dispersed calcium ions in depilatory products, as described in example 1. The difference lies in that:
the depilatory product comprises 4 parts by weight of pre-dispersed calcium ions and 3 parts by weight of thioglycolic acid.
Example 7
Example 7 provides the use of said pre-dispersed calcium ions in an epilatory product, in the same manner as in example 1. The difference lies in that:
the depilatory product comprises the raw materials of 10 parts by weight of pre-dispersed calcium ions and 3 parts by weight of thioglycolic acid.
Example 8
Example 8 provides the use of said pre-dispersed calcium ions in depilatory products, as described in example 1. The difference lies in that:
the depilatory product comprises 4 parts by weight of pre-dispersed calcium ions and 4 parts by weight of thioglycolic acid.
Example 9
Example 9 provides the use of said pre-dispersed calcium ions in depilatory products, as described in example 1. The difference lies in that:
the depilatory product comprises 7 parts by weight of pre-dispersed calcium ions and 4 parts by weight of thioglycolic acid.
Example 10
Example 10 provides the use of said pre-dispersed calcium ions in an epilatory product, as described in example 1. The difference lies in that:
the depilatory product comprises the raw materials of 10 parts by weight of pre-dispersed calcium ions and 4 parts by weight of thioglycolic acid.
Comparative example 1
Comparative example 1 provides an epilatory product comprising, in parts by weight, a phase a, a phase B, and a phase C;
the phase A comprises: 0.2 part of thickening stabilizer, 10 parts of calcium thioglycolate, 70.1 parts of aqueous component, 3.4 parts of potassium hydroxide and 0.3 part of antioxidant;
the phase B comprises: 7.5 parts of emulsifier and 8 parts of grease;
the phase C comprises: 0.5 part of essence.
The thickening stabilizer is hydroxyethyl cellulose.
The hydroxyethyl cellulose was purchased from HHR250 hydroxyethyl cellulose manufactured by invested Limited, inc. of Ashland Asia (China).
The emulsifier is fatty alcohol and C20-40 alkanol polyether-10.
The fatty alcohol is cetearyl alcohol.
The weight ratio of the fatty alcohol to the C20-40 alkanol polyether-10 is 3.
The CAS number of cetostearyl alcohol is 67762-27-0.
The C20-40 alkanol polyether-10 was purchased from Hangzhou Fuda Fine oils, inc.
The oil is hydrocarbon oil or synthetic oil.
The hydrocarbon oil is mineral oil.
The mineral oil was purchased from south Tongdeli chemical Co.
The synthetic oil is glycerol stearate.
The CAS number of the glyceryl stearate is 85666-92-8.
The weight ratio of the hydrocarbon oil to the synthetic grease is 5.
The aqueous component is water.
The antioxidant is sodium bisulfite.
The essence is bought from flowery essence produced by Jinsu Suteng chemical technology Co., ltd.
The preparation method of the depilatory product specifically comprises the following steps:
a1, uniformly stirring and dispersing a thickening stabilizer in an aqueous component, adding an antioxidant, uniformly stirring, and heating to 70 ℃;
a2, adding potassium hydroxide under stirring, keeping the temperature of the system at 85 ℃, and continuously stirring and uniformly dispersing to obtain a mixed phase A;
a3, sequentially adding calcium thioglycolate, grease and an emulsifier into the mixed phase A in the step A2, stirring, cooling to 70 ℃, and homogenizing for 5min to obtain a first solution;
and A4, stirring the solution I, continuously cooling to 45 ℃, adding the phase C, uniformly stirring, cooling to 25 ℃, and discharging.
Performance test
1. Particle size
The depilatory products prepared in example 1 and comparative example 1 were each placed under a microscope and observed for particle size using a 640-fold mirror, as shown in fig. 1 and 2, respectively. As can be seen from the figure, the particles of the epilatory product prepared in example 1 are more uniform and finer.
2. Irritation and depilatory efficiency test
The depilatory products prepared in examples 1 and 3-10 were tested for irritation and depilatory time, respectively, by selecting 10 volunteers.
Irritation test methods: the skin on the inner side of the wrist was cleaned, 0.3 g of depilatory product was applied to the skin on the inner side of the wrist over an area of about 3 coins of 1 yuan, and left to stand for 1 hour and then wiped off, and according to skin reaction and feel, evaluation was carried out with 0 being no skin reaction and no stinging, 10 being significant skin erythema and stinging, scoring ranging from 0 to 10, and the results were averaged and reported in table 1.
Depilating time test method: selecting skin with medium hair density of four limbs, applying 0.3 g of depilatory product on the skin on the inner side of wrist to form an area of about 3 coins with 1 yuan, standing to observe hair bending, wiping off depilatory cream with paper towel to confirm hair removal, recording the time as the time required for depilation, and averaging the results and recording the average value in Table 1.
FIG. 3 is a graph comparing the irritation and depilating time of the depilatory products prepared in examples 3-5; FIG. 4 is a graph comparing the irritation and depilating time of the depilatory products prepared in examples 1, 6-7; figure 5 is a graph comparing the irritation and epilation time of the epilation products prepared in examples 8-10.
As can be seen from FIGS. 3 to 5 and Table 1, in the case of the same amount of thioglycolic acid, when the amount of pre-dispersed calcium ions was 1.5 to 3 times the amount of thioglycolic acid, the amount of pre-dispersed calcium ions increased, the irritation decreased, but the depilation time increased; when the dosage of the pre-dispersed calcium ions is 3 times or more than that of the thioglycolic acid, the unhairing irritation is not obvious, and the unhairing time is shortened along with the increase of the dosage of the thioglycolic acid. The depilatory product with the best depilatory time and irritation profile was prepared as in example 1.
3. Stability test
The depilatory products prepared in examples 1-10 and comparative example 1 were tested for heat and cold resistance using the QB/T5108-2017 standards for depilatory cream (milk), test for heat resistance: keeping the temperature at 40 ℃ for 24h, and obtaining the qualified product after the temperature is recovered to 25 ℃ without oil-water separation or layering; and (3) cold resistance testing: the temperature is kept for 24 hours at minus 8 ℃, and the product is qualified if no delamination phenomenon occurs after the temperature is restored to 25 ℃, and the result is recorded in a table 2.
TABLE 1
| Irritation property | Time of depilation | |
| Example 1 | 5.5 | 6.5 |
| Example 3 | 7 | 6.5 |
| Example 4 | 5 | 8 |
| Example 5 | 5 | 8 |
| Example 6 | 8 | 6 |
| Example 7 | 5 | 7.5 |
| Example 8 | 4 | 5.5 |
| Example 9 | 7.5 | 6 |
| Example 10 | 6 | 7 |
TABLE 2
| Heat resistance | Cold-resistant | |
| Example 1 | Qualified | Qualified |
| Example 2 | Qualified | Qualified |
| Example 3 | Qualified | Qualified |
| Example 4 | Qualified | Qualified |
| Example 5 | Qualified | Qualified |
| Example 6 | Qualified | Qualified |
| Example 7 | Qualified | Qualified |
| Example 8 | Qualified | Qualified |
| Example 9 | Qualified | Qualified |
| Example 10 | Qualified | Qualified |
| Comparative example 1 | Fail to be qualified | Fail to be qualified |
Claims (10)
1. The pre-dispersed calcium ions are characterized by comprising the following raw materials in parts by weight: 1-60 parts of calcium ion raw material, 0-5 parts of thickening stabilizer, 1-10 parts of emulsifier, 0-20 parts of grease and 10-70 parts of water-based component.
2. The pre-dispersed calcium ions of claim 1, wherein the calcium ion source comprises one or more of calcium hydroxide, calcium oxide, calcium sulfate, calcium chloride, and calcium citrate.
3. The predispersed calcium ion according to claim 2, wherein the thickening stabilizer comprises one or more of hydroxyethylcellulose, methylhydroxyethylcellulose, crosslinked carboxymethylcellulose, hydroxypropylmethylcellulose stearyloxy ether, hydroxypropylcellulose, hydroxyethylethylcellulose, carboxymethylhydroxyethylcellulose, cellulose gum, ethylcellulose, xanthan gum, gellan gum, gelatin, hydroxypropyl guar gum, carbomer, magnesium aluminum silicate, sodium alginate, polyvinyl alcohol, oxidized polyethylene.
4. The predispersed calcium ion according to claim 3, wherein the emulsifier comprises one or more of fatty alcohol polyoxyethylene ether, fatty alcohol, fatty acid, alkylphenol ethoxylates, ethoxylated lanolin, ethoxylated siloxanes, polyethylene glycol fatty acid esters, C20-40 alkanol polyether-10, alkyl glycosides, fatty acid monoglycerides, phosphate monoesters and diesters, and salts thereof.
5. The pre-dispersed calcium ions of claim 4, wherein the oil comprises one or more of hydrocarbon oil, synthetic oil, and animal and vegetable oil.
6. The predispersed calcium ion as claimed in claim 5, wherein the aqueous component comprises one or more of water, propylene glycol, glycerin, sorbitol, butylene glycol, pentylene glycol, hexylene glycol, octylene glycol, ethanol, phenoxyethanol.
7. A method for pre-dispersing calcium ions according to any one of claims 1 to 6, comprising the steps of:
s1, adding a calcium ion raw material into an aqueous component, mixing, stirring and dispersing until no agglomeration exists;
s2, under the stirring condition, adding the thickening stabilizer, and stirring and dispersing until no obvious particles exist;
and S3, adding the emulsifier and the grease, and stirring and dispersing uniformly.
8. Use of the predispersed calcium ions according to any one of claims 1-6 in an epilatory product comprising, in parts by weight, a phase A, a phase B, a phase C;
the phase A comprises: 0-3 parts of thickening stabilizer, 1-50 parts of pre-dispersed calcium ions, 35-90 parts of aqueous component, 2-5 parts of potassium hydroxide and 0-1 part of antioxidant;
the phase B comprises: 0.1-5 parts of thioglycolic acid, 2-10 parts of emulsifier, 0-30 parts of grease, 0-3 parts of filler and 0-2 parts of chelating agent;
the phase C comprises: 0.1-1.0 part of essence and 0-1 part of preservative.
9. Use of predispersed calcium ions in an epilation product according to claim 8, wherein the ratio by weight of thioglycolic acid to predispersed calcium ions is 1: (0.5-5).
10. Use of predispersed calcium ions in an epilation product according to claim 8 or 9, characterized in that the preparation process of the epilation product comprises the following steps: and uniformly mixing all the components of the phase A, adding the component of the phase B, uniformly mixing, and adding the component C to obtain the composition.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211249007.8A CN115607462A (en) | 2022-10-12 | 2022-10-12 | Pre-dispersed calcium ions, pre-dispersion method thereof and application of pre-dispersed calcium ions in depilatory products |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211249007.8A CN115607462A (en) | 2022-10-12 | 2022-10-12 | Pre-dispersed calcium ions, pre-dispersion method thereof and application of pre-dispersed calcium ions in depilatory products |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN115607462A true CN115607462A (en) | 2023-01-17 |
Family
ID=84862554
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202211249007.8A Pending CN115607462A (en) | 2022-10-12 | 2022-10-12 | Pre-dispersed calcium ions, pre-dispersion method thereof and application of pre-dispersed calcium ions in depilatory products |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN115607462A (en) |
Citations (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH11187826A (en) * | 1997-12-25 | 1999-07-13 | Sanei Gen Ffi Inc | Dispersion-stabilizing composition and dispersion-stabilized food using the same |
| CN1245511A (en) * | 1996-12-24 | 2000-02-23 | 旭化成工业株式会社 | Aqueous suspension composition and water-dispersible dry composition |
| US20120093896A1 (en) * | 2007-07-31 | 2012-04-19 | Ciba Corporation | Use of nanodispersions to protect water-soluble ingredients in cosmetic end formulations |
| CN103271843A (en) * | 2013-05-22 | 2013-09-04 | 江苏海川生物科技有限公司 | Medical depilatory cream and preparation method thereof |
| CN103491932A (en) * | 2011-04-28 | 2014-01-01 | 宝洁公司 | Method and kit for depilation |
| US20150202140A1 (en) * | 2012-08-02 | 2015-07-23 | Reckitt & Colman (Overseas) Limited | Depilatory Formulations And Methods Of Using Same |
| CN105342873A (en) * | 2015-11-02 | 2016-02-24 | 上海韵宜生物科技有限公司 | Novel skin care gel as well as preparation method and application thereof |
| CN107007481A (en) * | 2017-04-18 | 2017-08-04 | 上海相宜本草化妆品股份有限公司 | A kind of multiple emulsion compositons and preparation method thereof |
| CN107201062A (en) * | 2016-03-17 | 2017-09-26 | 高仁丽 | A kind of inorganic ceramic paint |
| CN109303704A (en) * | 2017-07-28 | 2019-02-05 | 张军喜 | Depilatory cream |
| CN112156039A (en) * | 2020-11-11 | 2021-01-01 | 广州德芙化妆品有限公司 | Depilatory preparation and preparation method thereof |
| CN113499281A (en) * | 2021-07-12 | 2021-10-15 | 上海菲珂尔化妆品有限公司 | Stable suspension system, preparation method thereof and cosmetic |
-
2022
- 2022-10-12 CN CN202211249007.8A patent/CN115607462A/en active Pending
Patent Citations (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1245511A (en) * | 1996-12-24 | 2000-02-23 | 旭化成工业株式会社 | Aqueous suspension composition and water-dispersible dry composition |
| JPH11187826A (en) * | 1997-12-25 | 1999-07-13 | Sanei Gen Ffi Inc | Dispersion-stabilizing composition and dispersion-stabilized food using the same |
| US20120093896A1 (en) * | 2007-07-31 | 2012-04-19 | Ciba Corporation | Use of nanodispersions to protect water-soluble ingredients in cosmetic end formulations |
| CN103491932A (en) * | 2011-04-28 | 2014-01-01 | 宝洁公司 | Method and kit for depilation |
| US20150202140A1 (en) * | 2012-08-02 | 2015-07-23 | Reckitt & Colman (Overseas) Limited | Depilatory Formulations And Methods Of Using Same |
| CN103271843A (en) * | 2013-05-22 | 2013-09-04 | 江苏海川生物科技有限公司 | Medical depilatory cream and preparation method thereof |
| CN105342873A (en) * | 2015-11-02 | 2016-02-24 | 上海韵宜生物科技有限公司 | Novel skin care gel as well as preparation method and application thereof |
| CN107201062A (en) * | 2016-03-17 | 2017-09-26 | 高仁丽 | A kind of inorganic ceramic paint |
| CN107007481A (en) * | 2017-04-18 | 2017-08-04 | 上海相宜本草化妆品股份有限公司 | A kind of multiple emulsion compositons and preparation method thereof |
| CN109303704A (en) * | 2017-07-28 | 2019-02-05 | 张军喜 | Depilatory cream |
| CN112156039A (en) * | 2020-11-11 | 2021-01-01 | 广州德芙化妆品有限公司 | Depilatory preparation and preparation method thereof |
| CN113499281A (en) * | 2021-07-12 | 2021-10-15 | 上海菲珂尔化妆品有限公司 | Stable suspension system, preparation method thereof and cosmetic |
Non-Patent Citations (1)
| Title |
|---|
| 李志达，等: "卷发剂原料巯基乙酸钙的制备", 《日用化学工业》, no. 6, pages 260 - 10 * |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CA2264877C (en) | Lip treatment containing live yeast cell derivative | |
| JP5096742B2 (en) | Composition for scalp and hair | |
| JP3242893B2 (en) | Use of microdispersions of waxes in cosmetic or dermatological compositions | |
| JP3112436B2 (en) | In particular, the use of honey as a keratolytic agent to improve the brightness of the skin facial and treat wrinkles | |
| CA2403704C (en) | Method for preparing high pressure/high shear dispersions containing physiologically active ingredients | |
| CN114246812A (en) | Skin cleaning composition and preparation method and application thereof | |
| KR101383217B1 (en) | Composition for preventing hair loss and promoting hair growth | |
| JP2001199937A (en) | Cosmetic oil solution, cosmetic and preparation use for external using the same | |
| JPH08325130A (en) | Cosmetic | |
| JP3590369B2 (en) | Cosmetic composition for preventing and treating acne containing cryptotanshinone | |
| JP2000319142A (en) | Permanent wave agent composition | |
| CN115607462A (en) | Pre-dispersed calcium ions, pre-dispersion method thereof and application of pre-dispersed calcium ions in depilatory products | |
| JP3040440B2 (en) | Skin improver | |
| JP3061295B2 (en) | Cosmetics | |
| JP4383630B2 (en) | Cosmetics | |
| CN101686926A (en) | Hair styling and conditioning personal care films | |
| JP6754546B2 (en) | Skin care method | |
| KR100774550B1 (en) | Topical formulation for the treatment of dermatological conditions | |
| JP7294713B2 (en) | skin cosmetics | |
| JP2002332207A (en) | Solid transparent cosmetic | |
| JP3044690B2 (en) | Cosmetics | |
| JP6209350B2 (en) | Acne control composition, external preparation for skin and cosmetics | |
| JP2000154120A (en) | Hair restoring and growing composition | |
| JP2000154121A (en) | Hair-restoring and growing composition | |
| JP2017171629A (en) | Composition for external use |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |