CN115607462A - Pre-dispersed calcium ions, pre-dispersion method thereof and application of pre-dispersed calcium ions in depilatory products - Google Patents
Pre-dispersed calcium ions, pre-dispersion method thereof and application of pre-dispersed calcium ions in depilatory products Download PDFInfo
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- CN115607462A CN115607462A CN202211249007.8A CN202211249007A CN115607462A CN 115607462 A CN115607462 A CN 115607462A CN 202211249007 A CN202211249007 A CN 202211249007A CN 115607462 A CN115607462 A CN 115607462A
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- calcium ions
- calcium
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- oil
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- BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 title claims abstract description 91
- 229910001424 calcium ion Inorganic materials 0.000 title claims abstract description 91
- 238000000034 method Methods 0.000 title claims abstract description 20
- 230000002951 depilatory effect Effects 0.000 title abstract description 79
- 239000006185 dispersion Substances 0.000 title description 8
- CWERGRDVMFNCDR-UHFFFAOYSA-N thioglycolic acid Chemical compound OC(=O)CS CWERGRDVMFNCDR-UHFFFAOYSA-N 0.000 claims abstract description 72
- 239000003995 emulsifying agent Substances 0.000 claims abstract description 27
- 239000004519 grease Substances 0.000 claims abstract description 27
- 239000002994 raw material Substances 0.000 claims abstract description 24
- 230000008719 thickening Effects 0.000 claims abstract description 23
- 239000003381 stabilizer Substances 0.000 claims abstract description 21
- 238000002360 preparation method Methods 0.000 claims abstract description 14
- 238000003756 stirring Methods 0.000 claims description 39
- 239000003921 oil Substances 0.000 claims description 31
- 235000019198 oils Nutrition 0.000 claims description 31
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 claims description 27
- -1 stearyloxy Chemical group 0.000 claims description 24
- 239000002245 particle Substances 0.000 claims description 15
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 15
- 239000003963 antioxidant agent Substances 0.000 claims description 13
- 230000003078 antioxidant effect Effects 0.000 claims description 13
- 235000015112 vegetable and seed oil Nutrition 0.000 claims description 13
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- 235000014113 dietary fatty acids Nutrition 0.000 claims description 11
- 239000000194 fatty acid Substances 0.000 claims description 11
- 229930195729 fatty acid Natural products 0.000 claims description 11
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- 235000019447 hydroxyethyl cellulose Nutrition 0.000 claims description 9
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 8
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 7
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- 150000004665 fatty acids Chemical class 0.000 claims description 7
- 238000002156 mixing Methods 0.000 claims description 7
- SVTBMSDMJJWYQN-UHFFFAOYSA-N 2-methylpentane-2,4-diol Chemical compound CC(O)CC(C)(C)O SVTBMSDMJJWYQN-UHFFFAOYSA-N 0.000 claims description 6
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims description 6
- 239000004166 Lanolin Substances 0.000 claims description 5
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- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 claims description 3
- 229940043375 1,5-pentanediol Drugs 0.000 claims description 3
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 claims description 3
- RWLALWYNXFYRGW-UHFFFAOYSA-N 2-Ethyl-1,3-hexanediol Chemical compound CCCC(O)C(CC)CO RWLALWYNXFYRGW-UHFFFAOYSA-N 0.000 claims description 3
- QCDWFXQBSFUVSP-UHFFFAOYSA-N 2-phenoxyethanol Chemical compound OCCOC1=CC=CC=C1 QCDWFXQBSFUVSP-UHFFFAOYSA-N 0.000 claims description 3
- NIXOWILDQLNWCW-UHFFFAOYSA-N Acrylic acid Chemical compound OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims description 3
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- 239000001856 Ethyl cellulose Substances 0.000 claims description 3
- ZZSNKZQZMQGXPY-UHFFFAOYSA-N Ethyl cellulose Chemical compound CCOCC1OC(OC)C(OCC)C(OCC)C1OC1C(O)C(O)C(OC)C(CO)O1 ZZSNKZQZMQGXPY-UHFFFAOYSA-N 0.000 claims description 3
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- SNAAJJQQZSMGQD-UHFFFAOYSA-N aluminum magnesium Chemical compound [Mg].[Al] SNAAJJQQZSMGQD-UHFFFAOYSA-N 0.000 claims description 3
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- BRPQOXSCLDDYGP-UHFFFAOYSA-N calcium oxide Chemical compound [O-2].[Ca+2] BRPQOXSCLDDYGP-UHFFFAOYSA-N 0.000 claims description 3
- 239000000292 calcium oxide Substances 0.000 claims description 3
- ODINCKMPIJJUCX-UHFFFAOYSA-N calcium oxide Inorganic materials [Ca]=O ODINCKMPIJJUCX-UHFFFAOYSA-N 0.000 claims description 3
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- 235000011187 glycerol Nutrition 0.000 claims description 3
- 229930182470 glycoside Natural products 0.000 claims description 3
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- 229920013818 hydroxypropyl guar gum Polymers 0.000 claims description 3
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 claims description 3
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 claims description 3
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 claims description 3
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 claims description 3
- WCVRQHFDJLLWFE-UHFFFAOYSA-N pentane-1,2-diol Chemical compound CCCC(O)CO WCVRQHFDJLLWFE-UHFFFAOYSA-N 0.000 claims description 3
- 229960005323 phenoxyethanol Drugs 0.000 claims description 3
- 239000010452 phosphate Substances 0.000 claims description 3
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 claims description 3
- 229920001223 polyethylene glycol Polymers 0.000 claims description 3
- 229940051841 polyoxyethylene ether Drugs 0.000 claims description 3
- 229920000056 polyoxyethylene ether Polymers 0.000 claims description 3
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- 150000003839 salts Chemical class 0.000 claims description 3
- 235000010413 sodium alginate Nutrition 0.000 claims description 3
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- 239000000600 sorbitol Substances 0.000 claims description 3
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- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 claims description 2
- 239000001110 calcium chloride Substances 0.000 claims description 2
- 229910001628 calcium chloride Inorganic materials 0.000 claims description 2
- FNAQSUUGMSOBHW-UHFFFAOYSA-H calcium citrate Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O.[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O FNAQSUUGMSOBHW-UHFFFAOYSA-H 0.000 claims description 2
- 239000001354 calcium citrate Substances 0.000 claims description 2
- AXCZMVOFGPJBDE-UHFFFAOYSA-L calcium dihydroxide Chemical compound [OH-].[OH-].[Ca+2] AXCZMVOFGPJBDE-UHFFFAOYSA-L 0.000 claims description 2
- 239000000920 calcium hydroxide Substances 0.000 claims description 2
- 229910001861 calcium hydroxide Inorganic materials 0.000 claims description 2
- 239000000203 mixture Substances 0.000 claims description 2
- 235000013337 tricalcium citrate Nutrition 0.000 claims description 2
- CNYFJCCVJNARLE-UHFFFAOYSA-L calcium;2-sulfanylacetic acid;2-sulfidoacetate Chemical compound [Ca+2].[O-]C(=O)CS.[O-]C(=O)CS CNYFJCCVJNARLE-UHFFFAOYSA-L 0.000 abstract description 26
- 230000035617 depilation Effects 0.000 abstract description 15
- 230000008569 process Effects 0.000 abstract description 9
- 238000004519 manufacturing process Methods 0.000 abstract description 5
- CWERGRDVMFNCDR-UHFFFAOYSA-M thioglycolate(1-) Chemical compound [O-]C(=O)CS CWERGRDVMFNCDR-UHFFFAOYSA-M 0.000 abstract description 3
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- VBICKXHEKHSIBG-UHFFFAOYSA-N 1-monostearoylglycerol Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(O)CO VBICKXHEKHSIBG-UHFFFAOYSA-N 0.000 description 10
- GLDOVTGHNKAZLK-UHFFFAOYSA-N octadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCO GLDOVTGHNKAZLK-UHFFFAOYSA-N 0.000 description 10
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/46—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q9/00—Preparations for removing hair or for aiding hair removal
- A61Q9/04—Depilatories
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- Animal Behavior & Ethology (AREA)
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Abstract
The invention relates to the technical field of depilation, in particular to the field of IPC A61K8, and more particularly relates to pre-dispersed calcium ions and a single-component ceramic coating prepared from the same. The preparation raw materials of the pre-dispersed calcium ions comprise: 1-60 parts of calcium ion raw material, 0-5 parts of first thickening stabilizer, 1-10 parts of first emulsifier, 0-20 parts of first grease and 10-70 parts of first aqueous component. The depilatory product produced by using thioglycollic acid and pre-dispersed calcium ions is economic, low in cost, high in cost performance and long in shelf life, and can ensure that the production of domestic depilatory product manufacturers is not influenced by foreign raw material suppliers and sales; meanwhile, compared with a calcium thioglycollate process, the intermediate links are omitted, the formula cost can be greatly reduced, and the depilatory product prepared by adopting the thioglycollate and pre-dispersed calcium ions has higher cost performance.
Description
Technical Field
The invention relates to the technical field of depilation, in particular to the field of IPC A61K8, and more particularly relates to pre-dispersed calcium ions and a single-component ceramic coating prepared from the same.
Background
Chemical depilation is a method for removing hairs after dissolving the hairs by utilizing the chemical action of a chemical depilatory and the keratin, because partial hair roots under the epidermis can also be dissolved by the chemical depilatory, the hair regeneration speed is slower than that of a scraping method, the effect can last for more than 2 weeks, and the chemical depilation method has the advantages that: simple and rapid, and relatively low cost.
Chemical depilation uses a chemical agent which dissolves the structure of the hair, penetrates into the hair follicle within a few minutes, softens and breaks the keratin molecular chains constituting the hair, removes the inelegant body hair at the body parts such as the armpit, and has the dual effects of depilation and skin care. The main component of the preparation is thioglycolic acid (calcium), and the preparation is suitable for people who are afraid of pain but have low possibility of skin allergy.
A common chemical depilatory product today uses calcium thioglycolate, which is used to reduce irritation. Calcium thioglycolate, namely calcium thioglycolate, white crystalline powder, is insoluble in water, slightly soluble in alcohol and has special smell of sulfhydryl compounds, and the calcium thioglycolate can destroy disulfide bonds in hair protein to achieve the aim of lightening or dissolving hair, thereby achieving the hair removal effect. The pH value of the system, the amount of calcium thioglycolate and the dispersion state influence the depilation effect. Because calcium thioglycolate is insoluble in water and grease, calcium thioglycolate particles are larger after powdery calcium thioglycolate is added into a depilatory formula and dispersed, the depilatory effect is influenced, and the appearance of the paste is not fine enough.
Calcium thioglycolate is an acid-base neutralization process in the synthesis process, and high temperature in the process can cause partial sulfydryl to be oxidized and damaged, reduce the hair removal effect of a final product and easily cause yellowing of the product. Meanwhile, the existence of calcium thioglycolate in larger particles can also reduce the depilatory effect and lead to insufficient brightness of the paste.
Calcium thioglycolate is generally insoluble in water and grease, so the particle size of calcium thioglycolate added into a depilation system is the dispersed particle size of thioglycolic acid in the final product, the dispersed particle size of calcium thioglycolate can influence depilation efficiency, and the smaller the particle, the more uniform the system and the higher the depilation efficiency.
Patent document CN112156039A discloses a depilatory preparation and a preparation method thereof, wherein myristic acid and pine needle extract are added to obtain the depilatory preparation, which has a significant hair growth inhibition effect, but the particle size and dispersion degree of calcium thioglycolate in the system are not significantly improved.
Patent document CN109303704A discloses a depilatory cream, which can improve the depilatory experience of consumers by adding diatomite to adsorb the taste of calcium thioglycolate, but does not significantly improve the particle size and dispersion degree of calcium thioglycolate in the system.
Disclosure of Invention
In order to solve the problems, the invention provides a pre-dispersed calcium ion which comprises, by weight, 1-60 parts of calcium ion raw materials, 0-5 parts of thickening stabilizing agents, 1-10 parts of emulsifying agents, 0-20 parts of grease and 10-70 parts of water-based components.
Preferably, the calcium ion raw material comprises one or more of calcium hydroxide, calcium oxide, calcium sulfate, calcium chloride and calcium citrate.
Preferably, the thickening stabilizer comprises one or more of hydroxyethyl cellulose, methyl hydroxyethyl cellulose, cross-linked carboxymethyl cellulose, hydroxypropyl methyl cellulose stearyloxy ether, hydroxypropyl cellulose, hydroxyethyl ethyl cellulose, carboxymethyl hydroxyethyl cellulose, cellulose gum, ethyl cellulose, xanthan gum, gellan gum, gelatin, hydroxypropyl guar gum, carbomer, magnesium aluminum silicate, sodium alginate, polyvinyl alcohol, polyethylene oxide.
Preferably, the emulsifier comprises one or more of fatty alcohol-polyoxyethylene ether, fatty alcohol, fatty acid, alkylphenol ethoxylates, ethoxylated lanolin, ethoxylated siloxane, polyethylene glycol fatty acid ester, C20-40 alkanol polyether-10, alkyl glycoside, fatty acid monoglyceride, phosphate monoester and diester, and salts thereof.
Preferably, the fatty alcohol comprises one or more of cetearyl alcohol, decyl alcohol, capryl alcohol, lauryl alcohol, myristyl alcohol, capryl decyl alcohol, palmityl alcohol, stearyl alcohol, lauryl/myristyl alcohol, oleyl alcohol.
Preferably, the fatty acid comprises one or more of palmitoleic acid, lauric acid, myristic acid, oleic acid, stearic acid, arachidic acid, vaccenic acid, linoleic acid.
Preferably, the grease comprises one or more of hydrocarbon oil, synthetic grease and animal and vegetable oil.
Preferably, the hydrocarbon oil comprises one or more of mineral oil, petrolatum, C15-19 alkanes, hydrogenated polydecene, isohexadecane, polyethylene, hydrogenated polyisobutene, paraffin, isododecane, isohexadecane, isomeric eicosane, squalane, ceresin, microcrystalline wax, octadecene.
Preferably, the synthetic oil or fat includes one or more of silicone oil, glyceryl stearate, propylheptyl caprylate, polyhydroxystearic acid, isopropyl myristate, isopropyl palmitate, neopentyl glycol di (ethylhexanoate), isooctyl palmitate, methyl oleate, isooctyl oleate, decyl oleate, oleyl oleate, isononyl isononanoate, C12-C15 benzoate, glyceryl hydroxystearate, cholesteryl hydroxystearate, dioctyl carbonate, isotridecyl isononanoate, bisethylhexyl carbonate, pentaerythritol distearate, diisostearyl malate, caprylic/capric triglyceride, glyceryl tri (ethylhexanoate), triglycerol cocoate, triglycerol triisostearate, triisopolyglyceryl stearate, pentaerythritol tetrakis (2-ethylhexanoate), pentaerythritol tetraisostearate.
Preferably, the animal or vegetable fat includes one or more of lanolin, emu oil, horse fat, borage seed oil, kiwi seed oil, ginger root oil, soybean oil, safflower seed oil, olive oil, fruit fat oil, castor oil, evening primrose oil, rose hip oil, avocado oil, jojoba oil, grapeseed oil, meadowfoam seed oil, shea butter, cocoa butter, macadamia nut oil, camellia seed oil, palm kernel oil, camellia seed oil, rosa canina fruit oil, camellia seed oil, MORINGA OLEIFERA (MORINGA OLEIFERA) seed oil, latani oil, wheat germ oil, sweet almond oil, hydrogenated coconut oil, hydrogenated jojoba oil, hydrogenated shea butter oil, hydrogenated cocoa butter, hydrogenated mango butter, hydrogenated grape seed oil.
Preferably, the silicone oil comprises one or more of cyclopentadimethylsiloxane, trimethylsiloxysilicate, polydimethylsiloxane, dimethiconol, phenyl trimethicone, cetyl polydimethylsiloxane, octyl polydimethylsiloxane, stearyl polydimethylsiloxane.
Preferably, the aqueous component comprises one or more of water, propylene glycol, glycerol, sorbitol, butylene glycol, pentylene glycol, hexylene glycol, octylene glycol, ethanol, phenoxyethanol.
The applicant has unexpectedly found that by selecting specific raw materials to prepare pre-dispersed calcium ions, the fineness of the paste of the prepared depilatory product and the depilatory effect can be improved. The method is probably because the dispersion uniformity of calcium ions in a system can be increased after raw materials containing calcium ions are uniformly mixed in a specific system, and then pre-dispersed calcium ions with high dispersion uniformity are applied to a depilatory product and can react with thioglycolic acid to generate colloidal calcium thioglycolate precipitate, and the calcium thioglycolate precipitate synthesized by the pre-dispersed calcium ions with high dispersion uniformity has fine particles and is uniformly distributed, so that the prepared paste has high fineness, the depilatory effect of the depilatory product prepared can be effectively improved, and the problems that the final depilatory product is large in dispersed particles and the depilatory efficiency is influenced due to the fact that the thioglycolic acid is insoluble in a water phase and an oil phase are solved.
The invention provides a pre-dispersing method for pre-dispersing calcium ions in a second aspect, which comprises the following steps:
s1, adding a calcium ion raw material into an aqueous component, mixing, stirring and dispersing until no agglomeration exists;
s2, under the stirring condition, adding the thickening stabilizer, and stirring and dispersing until no obvious particles exist;
and S3, adding the emulsifier and the grease, and stirring and dispersing uniformly.
The applicant has unexpectedly found that pre-dispersed calcium ions are prepared by emulsifying and dispersing calcium ion raw materials in a specific system in advance, and the pre-dispersed calcium ions are applied to depilatory products containing specific grease, emulsifier, thickening stability and other raw materials, so that the stability of the depilatory products in the preparation process can be improved. The reason is probably that in the production process of the depilatory product, thioglycolic acid and pre-dispersed calcium ions react to generate calcium thioglycolate, so that the acid-base concentration during acid-base neutralization can be effectively reduced, and the damage of the thioglycolic acid is reduced, so that the stability in the preparation process is improved, and by adopting the production mode, the oxidative damage of a calcium thioglycolate raw material in the synthesis and storage processes can be reduced, the shelf life of the depilatory product is prolonged, and generally 3-6 months can be prolonged.
The invention provides the application of the pre-dispersed calcium ions in the depilatory product, wherein the depilatory product comprises a phase A, a phase B and a phase C in parts by weight;
preferably, the phase a comprises: 0-3 parts of thickening stabilizer, 1-50 parts of pre-dispersed calcium ions, 35-90 parts of aqueous component, 2-5 parts of potassium hydroxide and 0-1 part of antioxidant;
preferably, the phase B comprises: 0.1-5 parts of thioglycolic acid, 2-10 parts of emulsifier, 0-30 parts of grease, 0-3 parts of filler and 0-2 parts of chelating agent;
preferably, the phase C comprises: 0.1-1.0 part of essence and 0-1 part of preservative.
Preferably, the weight ratio of the thioglycolic acid to the pre-dispersed calcium ions is 1: (0.5-5).
The applicant has surprisingly found that by controlling the weight ratio of thioglycolic acid to predispersed calcium ions, the irritation and epilation efficiency of the epilation product can be adjusted, thereby meeting the needs of the vast majority of the population. This is probably due to the fact that in the art, the higher ratio by weight of calcium ion/thioglycolic acid in thioglycolic acid based depilatory products, the irritation of the depilatory product is reduced and the depilatory speed is slowed; with a low weight ratio of calcium ions/thioglycolic acid, the irritation of the epilation product will increase, while the epilation speed will be faster. In the practical application process, the hair of the western people is vigorous, and the hair removal is difficult, so a hair removal product with a low weight ratio of calcium ions to thioglycollic acid is needed, while the hair of the oriental people is sparse, the skin is fine and smooth, so the weight ratio of the calcium ions to the thioglycollic acid in the hair removal product needs to be higher. The traditional method for preparing the depilatory product by using calcium thioglycolate fixes the ratio of calcium to thioglycolate, so that the irritation and the depilatory efficiency of the depilatory product cannot be adjusted and balanced, and one product cannot meet the requirements of most people. The application prepares pre-dispersed calcium ions firstly, and then the pre-dispersed calcium ions are mixed with thioglycolic acid to react to prepare the unhairing product, so that the problem of the requirements of different crowds is effectively solved, the weight ratio of the thioglycolic acid to the pre-dispersed calcium ions can be flexibly adjusted according to different requirements, the formula is flexible and flexible, and different requirements of different world races in east and west can be met.
Preferably, the antioxidant comprises sodium bisulfite, sodium sulfite, sodium metabisulfite, sodium thiosulfate.
Preferably, the thickening stabilizer comprises one or more of hydroxyethyl cellulose, methyl hydroxyethyl cellulose, cross-linked carboxymethyl cellulose, hydroxypropyl methyl cellulose stearyloxy ether, hydroxypropyl cellulose, hydroxyethyl ethyl cellulose, carboxymethyl hydroxyethyl cellulose, cellulose gum, ethyl cellulose, xanthan gum, gellan gum, gelatin, hydroxypropyl guar gum, carbomer, magnesium aluminum silicate, sodium alginate, polyvinyl alcohol, oxidized polyethylene.
Preferably, the emulsifier comprises one or more of fatty alcohol-polyoxyethylene ether, fatty alcohol, fatty acid, alkylphenol ethoxylates, ethoxylated lanolin, ethoxylated siloxane, polyethylene glycol fatty acid ester, C20-40 alkanol polyether-10, alkyl glycoside, fatty acid monoglyceride, phosphate monoester and diester, and salts thereof.
Preferably, the fatty alcohol comprises one or more of cetearyl alcohol, decyl alcohol, capryl alcohol, lauryl alcohol, myristyl alcohol, capryl decyl alcohol, palmityl alcohol, stearyl alcohol, lauryl/myristyl alcohol, oleyl alcohol.
Preferably, the fatty acid comprises one or more of palmitoleic acid, lauric acid, myristic acid, oleic acid, stearic acid, arachidic acid, vaccenic acid, linoleic acid.
Preferably, the grease comprises one or more of hydrocarbon oil, synthetic grease and animal and vegetable oil.
Preferably, the hydrocarbon oil comprises one or more of mineral oil, petrolatum, C15-19 alkanes, hydrogenated polydecene, isohexadecane, polyethylene, hydrogenated polyisobutene, paraffin, isododecane, isohexadecane, isomeric eicosane, ceresin, microcrystalline wax, octadecene.
Preferably, the synthetic oil includes one or more of silicone oil, glyceryl stearate, propylheptyl caprylate, polyhydroxystearic acid, isopropyl myristate, isopropyl palmitate, neopentyl glycol di (ethylhexanoate), isooctyl palmitate, methyl oleate, isooctyl oleate, decyl oleate, oleyl oleate, isononyl isononanoate, C12-C15 benzoates, glyceryl hydroxystearate, cholesterol hydroxystearate, dioctyl carbonate, isotridecyl isononanoate, bisethylhexyl carbonate, pentaerythritol distearate, diisostearyl malate, caprylic/capric triglyceride, glyceryl tri (ethylhexanoate), triglycerol cocoate, glyceryl triisostearate, polyglyceryl triisostearate, pentaerythritol tetrakis (2-ethylhexanoate), pentaerythritol tetraisostearate.
Preferably, the animal or vegetable fat includes one or more of squalane, lanolin, emu oil, horse fat, borage seed oil, kiwi seed oil, ginger root oil, soybean oil, safflower seed oil, olive oil, fruit fat oil, castor oil, evening primrose oil, rose hip oil, avocado oil, jojoba oil, grape seed oil, meadowfoam seed oil, shea butter, cocoa seed fat, macadamia nut oil, camellia seed oil, palm kernel oil, camellia seed oil, rosa canina fruit oil, camellia seed oil, MORINGA OLEIFERA (MORINGA OLEIFERA) seed oil, latani oil, wheat germ oil, sweet almond oil, hydrogenated coconut oil, hydrogenated jojoba oil, hydrogenated fruit tree fruit fat oil, hydrogenated cocoa butter, hydrogenated mango fat, hydrogenated grape seed oil.
Preferably, the silicone oil comprises one or more of cyclopentadimethylsiloxane, trimethylsiloxysilicate, polydimethylsiloxane, dimethiconol, phenyl trimethicone, cetyl dimethicone, octyl methicone, stearyl dimethicone.
Preferably, the aqueous component comprises one or more of water, propylene glycol, glycerol, sorbitol, butylene glycol, pentylene glycol, hexylene glycol, octylene glycol, ethanol, phenoxyethanol.
Preferably, the filler comprises one or more of titanium dioxide, zinc oxide, ferric oxide, mica, ultramarine, carbon black, chrome green, talcum powder, diatomite, silica, boron nitride, alumina, stearic acid, polyhydroxystearic acid, polymethylsilsesquioxane, methacrylic acid cross-linked polymer and calcium carbonate.
Preferably, the chelating agent comprises disodium EDTA, DTPA-5Na.
Preferably, the preservative comprises sodium benzoate, potassium sorbate, sodium lactate, propyl paraben.
Preferably, the method of preparing the depilatory product comprises the steps of: and uniformly mixing all the components of the phase A, adding the component of the phase B, uniformly mixing, and adding the component C to obtain the composition.
Further preferably, the preparation method of the depilatory product specifically comprises the following steps:
a1, uniformly stirring and dispersing a thickening stabilizer in an aqueous component, adding pre-dispersed calcium ions and an antioxidant, uniformly stirring, and heating to 60-80 ℃;
a2, adding potassium hydroxide under stirring, keeping the temperature of the system at 85-90 ℃, and continuously stirring and dispersing uniformly to obtain a mixed phase A;
a3, sequentially adding thioglycollic acid, grease, an emulsifier, a filling agent and a chelating agent into the mixed phase A in the step A2, stirring, cooling to 60-80 ℃, and homogenizing for 1-10min to obtain a solution I;
and A4, stirring the solution I, continuously cooling to 40-50 ℃, adding the phase C, uniformly stirring, cooling to room temperature, and discharging.
Has the advantages that:
1. according to the invention, the pre-dispersed calcium ions are prepared by selecting specific raw materials, so that the fineness of the paste of the prepared depilatory product and the depilatory effect can be improved.
2. The calcium ion raw material is emulsified and dispersed in a specific system in advance to prepare the pre-dispersed calcium ions, and the pre-dispersed calcium ions are applied to the depilating product containing the raw materials such as specific grease, emulsifier, thickening stability and the like, so that the stability of the depilating product in the preparation process can be improved.
3. The invention can adjust the irritation and the depilation efficiency of the depilation product by controlling the weight ratio of the thioglycolic acid to the pre-dispersed calcium ions, thereby meeting the requirements of most people.
4. The method for producing depilatory products by using thioglycolic acid and pre-dispersed calcium ions is economic, low in cost, high in cost performance and long in shelf life of the products, and can ensure that the production of domestic depilatory products is not influenced by foreign raw material suppliers and sales; meanwhile, compared with a calcium thioglycollate process, the intermediate links are omitted, the formula cost can be greatly reduced, and the depilatory product prepared by adopting the thioglycollate and pre-dispersed calcium ions has higher cost performance.
5. The process for synthesizing the calcium thioglycolate in the process of producing the depilatory product by using the thioglycolic acid and the pre-dispersed calcium ions fills the domestic blank, and has larger technical and market effects.
Drawings
FIG. 1 is a photograph of a depilatory product prepared in example 1 under a 640-fold microscope;
FIG. 2 is a photograph of the epilatory product prepared in comparative example 1 at 640 times microscope;
FIG. 3 is a graph comparing the irritation and depilating time of the depilatory products prepared in examples 3-5;
FIG. 4 is a graph comparing the irritation and depilating time of the depilatory products prepared in examples 1, 6-7;
FIG. 5 is a graph comparing the irritation and depilating time of the depilatory products prepared in examples 8-10.
Detailed Description
Examples
Example 1
The calcium ion raw material is calcium oxide.
The thickening stabilizer is hydroxyethyl cellulose.
The hydroxyethylcellulose was purchased from HHR250 hydroxyethylcellulose produced by Hish (China) investment Limited.
The emulsifier is fatty alcohol and C20-40 alkanol polyether-10.
The fatty alcohol is cetostearyl alcohol.
The weight ratio of the fatty alcohol to the C20-40 alkanol polyether-10 is 3.
The CAS number of cetostearyl alcohol is 67762-27-0.
The C20-40 alkanol polyether-10 was purchased from Hangzhou Fuda Fine oils, inc.
The oil is hydrocarbon oil or synthetic oil.
The hydrocarbon oil is mineral oil.
The mineral oil was purchased from south Tongdeli chemical Co.
The synthetic grease is glycerol stearate.
The CAS number of the glyceryl stearate is 85666-92-8.
The weight ratio of the hydrocarbon oil to the synthetic grease is 5.
The aqueous component is water.
The invention provides a pre-dispersing method for pre-dispersing calcium ions in a second aspect, which comprises the following steps:
s1, adding a calcium ion raw material into an aqueous component, and mixing, stirring and dispersing until no agglomeration exists;
s2, under the condition of stirring, adding the thickening stabilizer, and stirring and dispersing until no obvious particles exist;
and S3, adding the emulsifier and the grease, and stirring and dispersing uniformly.
The invention provides the application of the pre-dispersed calcium ions in the depilatory product, wherein the depilatory product comprises a phase A, a phase B and a phase C in parts by weight;
the phase A comprises: 0.2 part of thickening stabilizer, 7 parts of pre-dispersed calcium ions, 70.1 parts of aqueous component, 3.4 parts of potassium hydroxide and 0.3 part of antioxidant;
the phase B comprises: 3 parts of thioglycolic acid, 7.5 parts of emulsifier and 8 parts of grease;
the phase C comprises: 0.5 part of essence.
The components of the thickening stabilizer, the emulsifier, the water-based component and the grease are the same as those of the thickening stabilizer, the emulsifier, the water-based component and the grease in the pre-dispersed calcium ions.
The antioxidant is sodium bisulfite.
The essence is bought from flowery essence produced by Jinsu Suteng chemical technology Co., ltd.
The preparation method of the depilatory product specifically comprises the following steps:
a1, uniformly stirring and dispersing a thickening stabilizer in an aqueous component, adding pre-dispersed calcium ions and an antioxidant, uniformly stirring, and heating to 70 ℃;
a2, adding potassium hydroxide under stirring, keeping the temperature of the system at 85 ℃, and continuously stirring and uniformly dispersing to obtain a mixed phase A;
a3, sequentially adding thioglycollic acid, grease and an emulsifier into the mixed phase A in the step A2, stirring, cooling to 70 ℃, and homogenizing for 5min to obtain a first solution;
and A4, stirring the solution I, continuously cooling to 45 ℃, adding the phase C, uniformly stirring, cooling to 25 ℃, and discharging.
Example 2
Example 2 provides the use of said pre-dispersed calcium ions in depilatory products, as described in example 1. The difference lies in that:
the depilatory product comprises a phase A, a phase B and a phase C in parts by weight;
the phase A comprises: 7 parts of pre-dispersed calcium ions, 75.5 parts of water-based component, 5 parts of potassium hydroxide and 0.3 part of antioxidant;
the phase B comprises: 3 parts of thioglycolic acid, 7.5 parts of emulsifier and 1 part of chelating agent;
the phase C comprises: 0.5 part of essence and 0.3 part of preservative.
The components of the emulsifier and the aqueous component are the same as those of the emulsifier and the aqueous component in the pre-dispersed calcium ions.
The antioxidant is sodium bisulfite.
The chelating agent is DTPA-5Na.
The preservative is sodium benzoate.
The essence is purchased from flowery essence produced by Jinan Xin Suteng chemical technology Limited.
The preparation method of the depilatory product specifically comprises the following steps:
a1, uniformly stirring and dispersing pre-dispersed calcium ions and an antioxidant in an aqueous component, and heating to 70 ℃;
a2, adding potassium hydroxide under stirring, keeping the temperature of the system at 85 ℃, and continuously stirring and uniformly dispersing to obtain a mixed phase A;
a3, sequentially adding thioglycollic acid, an emulsifier and a chelating agent into the mixed phase A in the step A2, stirring, cooling to 70 ℃, and homogenizing for 5min to obtain a first solution;
and A4, stirring the solution I, continuously cooling to 45 ℃, adding the phase C, uniformly stirring, cooling to 25 ℃, and discharging.
Example 3
Example 3 provides the use of said pre-dispersed calcium ions in depilatory products, as described in example 1. The difference lies in that:
the depilatory product comprises 4 parts by weight of pre-dispersed calcium ions and 2 parts by weight of thioglycolic acid.
Example 4
Example 4 provides the use of said pre-dispersed calcium ions in depilatory products, as described in example 1. The difference lies in that:
the depilatory product comprises 7 parts by weight of pre-dispersed calcium ions and 2 parts by weight of thioglycolic acid.
Example 5
Example 5 provides the use of said pre-dispersed calcium ions in depilatory products, as described in example 1. The difference lies in that:
the depilatory product is prepared from the raw materials of 10 parts by weight of pre-dispersed calcium ions and 2 parts by weight of thioglycolic acid.
Example 6
Example 6 provides the use of said pre-dispersed calcium ions in depilatory products, as described in example 1. The difference lies in that:
the depilatory product comprises 4 parts by weight of pre-dispersed calcium ions and 3 parts by weight of thioglycolic acid.
Example 7
Example 7 provides the use of said pre-dispersed calcium ions in an epilatory product, in the same manner as in example 1. The difference lies in that:
the depilatory product comprises the raw materials of 10 parts by weight of pre-dispersed calcium ions and 3 parts by weight of thioglycolic acid.
Example 8
Example 8 provides the use of said pre-dispersed calcium ions in depilatory products, as described in example 1. The difference lies in that:
the depilatory product comprises 4 parts by weight of pre-dispersed calcium ions and 4 parts by weight of thioglycolic acid.
Example 9
Example 9 provides the use of said pre-dispersed calcium ions in depilatory products, as described in example 1. The difference lies in that:
the depilatory product comprises 7 parts by weight of pre-dispersed calcium ions and 4 parts by weight of thioglycolic acid.
Example 10
Example 10 provides the use of said pre-dispersed calcium ions in an epilatory product, as described in example 1. The difference lies in that:
the depilatory product comprises the raw materials of 10 parts by weight of pre-dispersed calcium ions and 4 parts by weight of thioglycolic acid.
Comparative example 1
Comparative example 1 provides an epilatory product comprising, in parts by weight, a phase a, a phase B, and a phase C;
the phase A comprises: 0.2 part of thickening stabilizer, 10 parts of calcium thioglycolate, 70.1 parts of aqueous component, 3.4 parts of potassium hydroxide and 0.3 part of antioxidant;
the phase B comprises: 7.5 parts of emulsifier and 8 parts of grease;
the phase C comprises: 0.5 part of essence.
The thickening stabilizer is hydroxyethyl cellulose.
The hydroxyethyl cellulose was purchased from HHR250 hydroxyethyl cellulose manufactured by invested Limited, inc. of Ashland Asia (China).
The emulsifier is fatty alcohol and C20-40 alkanol polyether-10.
The fatty alcohol is cetearyl alcohol.
The weight ratio of the fatty alcohol to the C20-40 alkanol polyether-10 is 3.
The CAS number of cetostearyl alcohol is 67762-27-0.
The C20-40 alkanol polyether-10 was purchased from Hangzhou Fuda Fine oils, inc.
The oil is hydrocarbon oil or synthetic oil.
The hydrocarbon oil is mineral oil.
The mineral oil was purchased from south Tongdeli chemical Co.
The synthetic oil is glycerol stearate.
The CAS number of the glyceryl stearate is 85666-92-8.
The weight ratio of the hydrocarbon oil to the synthetic grease is 5.
The aqueous component is water.
The antioxidant is sodium bisulfite.
The essence is bought from flowery essence produced by Jinsu Suteng chemical technology Co., ltd.
The preparation method of the depilatory product specifically comprises the following steps:
a1, uniformly stirring and dispersing a thickening stabilizer in an aqueous component, adding an antioxidant, uniformly stirring, and heating to 70 ℃;
a2, adding potassium hydroxide under stirring, keeping the temperature of the system at 85 ℃, and continuously stirring and uniformly dispersing to obtain a mixed phase A;
a3, sequentially adding calcium thioglycolate, grease and an emulsifier into the mixed phase A in the step A2, stirring, cooling to 70 ℃, and homogenizing for 5min to obtain a first solution;
and A4, stirring the solution I, continuously cooling to 45 ℃, adding the phase C, uniformly stirring, cooling to 25 ℃, and discharging.
Performance test
1. Particle size
The depilatory products prepared in example 1 and comparative example 1 were each placed under a microscope and observed for particle size using a 640-fold mirror, as shown in fig. 1 and 2, respectively. As can be seen from the figure, the particles of the epilatory product prepared in example 1 are more uniform and finer.
2. Irritation and depilatory efficiency test
The depilatory products prepared in examples 1 and 3-10 were tested for irritation and depilatory time, respectively, by selecting 10 volunteers.
Irritation test methods: the skin on the inner side of the wrist was cleaned, 0.3 g of depilatory product was applied to the skin on the inner side of the wrist over an area of about 3 coins of 1 yuan, and left to stand for 1 hour and then wiped off, and according to skin reaction and feel, evaluation was carried out with 0 being no skin reaction and no stinging, 10 being significant skin erythema and stinging, scoring ranging from 0 to 10, and the results were averaged and reported in table 1.
Depilating time test method: selecting skin with medium hair density of four limbs, applying 0.3 g of depilatory product on the skin on the inner side of wrist to form an area of about 3 coins with 1 yuan, standing to observe hair bending, wiping off depilatory cream with paper towel to confirm hair removal, recording the time as the time required for depilation, and averaging the results and recording the average value in Table 1.
FIG. 3 is a graph comparing the irritation and depilating time of the depilatory products prepared in examples 3-5; FIG. 4 is a graph comparing the irritation and depilating time of the depilatory products prepared in examples 1, 6-7; figure 5 is a graph comparing the irritation and epilation time of the epilation products prepared in examples 8-10.
As can be seen from FIGS. 3 to 5 and Table 1, in the case of the same amount of thioglycolic acid, when the amount of pre-dispersed calcium ions was 1.5 to 3 times the amount of thioglycolic acid, the amount of pre-dispersed calcium ions increased, the irritation decreased, but the depilation time increased; when the dosage of the pre-dispersed calcium ions is 3 times or more than that of the thioglycolic acid, the unhairing irritation is not obvious, and the unhairing time is shortened along with the increase of the dosage of the thioglycolic acid. The depilatory product with the best depilatory time and irritation profile was prepared as in example 1.
3. Stability test
The depilatory products prepared in examples 1-10 and comparative example 1 were tested for heat and cold resistance using the QB/T5108-2017 standards for depilatory cream (milk), test for heat resistance: keeping the temperature at 40 ℃ for 24h, and obtaining the qualified product after the temperature is recovered to 25 ℃ without oil-water separation or layering; and (3) cold resistance testing: the temperature is kept for 24 hours at minus 8 ℃, and the product is qualified if no delamination phenomenon occurs after the temperature is restored to 25 ℃, and the result is recorded in a table 2.
TABLE 1
| Irritation property | Time of depilation | |
| Example 1 | 5.5 | 6.5 |
| Example 3 | 7 | 6.5 |
| Example 4 | 5 | 8 |
| Example 5 | 5 | 8 |
| Example 6 | 8 | 6 |
| Example 7 | 5 | 7.5 |
| Example 8 | 4 | 5.5 |
| Example 9 | 7.5 | 6 |
| Example 10 | 6 | 7 |
TABLE 2
| Heat resistance | Cold-resistant | |
| Example 1 | Qualified | Qualified |
| Example 2 | Qualified | Qualified |
| Example 3 | Qualified | Qualified |
| Example 4 | Qualified | Qualified |
| Example 5 | Qualified | Qualified |
| Example 6 | Qualified | Qualified |
| Example 7 | Qualified | Qualified |
| Example 8 | Qualified | Qualified |
| Example 9 | Qualified | Qualified |
| Example 10 | Qualified | Qualified |
| Comparative example 1 | Fail to be qualified | Fail to be qualified |
Claims (10)
1. The pre-dispersed calcium ions are characterized by comprising the following raw materials in parts by weight: 1-60 parts of calcium ion raw material, 0-5 parts of thickening stabilizer, 1-10 parts of emulsifier, 0-20 parts of grease and 10-70 parts of water-based component.
2. The pre-dispersed calcium ions of claim 1, wherein the calcium ion source comprises one or more of calcium hydroxide, calcium oxide, calcium sulfate, calcium chloride, and calcium citrate.
3. The predispersed calcium ion according to claim 2, wherein the thickening stabilizer comprises one or more of hydroxyethylcellulose, methylhydroxyethylcellulose, crosslinked carboxymethylcellulose, hydroxypropylmethylcellulose stearyloxy ether, hydroxypropylcellulose, hydroxyethylethylcellulose, carboxymethylhydroxyethylcellulose, cellulose gum, ethylcellulose, xanthan gum, gellan gum, gelatin, hydroxypropyl guar gum, carbomer, magnesium aluminum silicate, sodium alginate, polyvinyl alcohol, oxidized polyethylene.
4. The predispersed calcium ion according to claim 3, wherein the emulsifier comprises one or more of fatty alcohol polyoxyethylene ether, fatty alcohol, fatty acid, alkylphenol ethoxylates, ethoxylated lanolin, ethoxylated siloxanes, polyethylene glycol fatty acid esters, C20-40 alkanol polyether-10, alkyl glycosides, fatty acid monoglycerides, phosphate monoesters and diesters, and salts thereof.
5. The pre-dispersed calcium ions of claim 4, wherein the oil comprises one or more of hydrocarbon oil, synthetic oil, and animal and vegetable oil.
6. The predispersed calcium ion as claimed in claim 5, wherein the aqueous component comprises one or more of water, propylene glycol, glycerin, sorbitol, butylene glycol, pentylene glycol, hexylene glycol, octylene glycol, ethanol, phenoxyethanol.
7. A method for pre-dispersing calcium ions according to any one of claims 1 to 6, comprising the steps of:
s1, adding a calcium ion raw material into an aqueous component, mixing, stirring and dispersing until no agglomeration exists;
s2, under the stirring condition, adding the thickening stabilizer, and stirring and dispersing until no obvious particles exist;
and S3, adding the emulsifier and the grease, and stirring and dispersing uniformly.
8. Use of the predispersed calcium ions according to any one of claims 1-6 in an epilatory product comprising, in parts by weight, a phase A, a phase B, a phase C;
the phase A comprises: 0-3 parts of thickening stabilizer, 1-50 parts of pre-dispersed calcium ions, 35-90 parts of aqueous component, 2-5 parts of potassium hydroxide and 0-1 part of antioxidant;
the phase B comprises: 0.1-5 parts of thioglycolic acid, 2-10 parts of emulsifier, 0-30 parts of grease, 0-3 parts of filler and 0-2 parts of chelating agent;
the phase C comprises: 0.1-1.0 part of essence and 0-1 part of preservative.
9. Use of predispersed calcium ions in an epilation product according to claim 8, wherein the ratio by weight of thioglycolic acid to predispersed calcium ions is 1: (0.5-5).
10. Use of predispersed calcium ions in an epilation product according to claim 8 or 9, characterized in that the preparation process of the epilation product comprises the following steps: and uniformly mixing all the components of the phase A, adding the component of the phase B, uniformly mixing, and adding the component C to obtain the composition.
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