CN115590676A - Eye surface drainage article - Google Patents

Abstract

The invention discloses an eye surface drainage object, which comprises a drainage inlet, a drainage outlet and a drainage channel arranged between the drainage inlet and the drainage outlet; the drainage inlet is used for inserting into the anterior chamber of the eye, and the drainage outlet is used for exposing the surface of the eye; also includes a fixation portion for engaging intraocular tissue. In the invention, the ocular surface drainage can establish an artificial drainage channel from the anterior chamber to the ocular surface, drain aqueous humor in eyes, reduce intraocular pressure and treat glaucoma; meanwhile, the liquid in the anterior chamber can be drained to the ocular surface to treat xerophthalmia. The fixing part and the intraocular tissues grow together, and when the eyes are squeezed or collided by external force, the ocular surface drainage can not be displaced; the drainage outlet of the ocular surface drainage matter is far away from the conjunctiva wound, so that the blockage of the tube can not occur. And the volume is small, the wound on the eye is small, the eye is quickly healed, the filtering bubble is not generated, and the appearance of the patient is not influenced.

Description

Eye surface drainage material

Technical Field

The invention relates to the technical field of eye implants, in particular to an eye surface drainage object.

Background

Glaucoma is the first irreversible blindness disease in the world and mainly affects women and Asian people. The prevalence of glaucoma increases year by year as the population ages.

Intraocular pressure (IOP) is an independent risk factor for glaucoma, leading to further damage to the optic nerve of the glaucoma, and control of IOP is an economical practice. Surgery to treat glaucoma may be a better treatment modality for glaucoma in developing countries. Current glaucoma treatment procedures are classified into a wide variety of procedures, such as laser therapy, trabeculectomy, drainage devices, and MIGS. Various surgical procedures or devices have certain limitations, such as short effective time of laser treatment, more postoperative complications of trabeculectomy, larger wound of drainage device, and limited intraocular pressure reducing effect of MIGS.

The following drainage methods also have their own disadvantages:

anterior chamber-trabecular MIGS drainage: the drainage tube or the drainage nail penetrates through the trabecular meshwork to communicate the anterior chamber with the schlemms tube, the aqueous humor is guided into the schlemms tube through the drainage device under the pressure action of the anterior chamber, and the aqueous humor in the schlemms tube completes aqueous humor circulation through the collecting tube and the scleral vein. Through the above process, the aqueous humor of the anterior chamber is reduced, and the intraocular pressure is lowered. However, the drainage method has limited pressure lowering capability and is suitable for treating glaucoma patients in the middle and early stages. And some patients have schlemms tube blockage or adhesion, and in this case, the effect of reducing intraocular pressure cannot be well achieved by communicating the anterior chamber with the trabecular meshwork.

Filtration bleb MIGS drainage: the conjunctiva or sclera is surgically or otherwise separated to form a bleb space. A drainage tube is used to penetrate the trabecular meshwork transsclerally, connecting the anterior chamber and the bleb. Under the pressure of the anterior chamber, aqueous humor is guided into the filtering bleb space through the drainage tube and absorbed by the sclera to complete aqueous humor circulation. Through the above process, the aqueous humor of the anterior chamber is reduced, and the intraocular pressure is lowered. The drainage effect of the drainage method has a direct relation with the form of the filtering bleb. The regeneration capacity of the sclera and the conjunctiva is strong, and after the filtering bleb is caused by operation, the risk of scarring is caused, and the drainage effect is reduced. And the filtering bubble is positioned on the ocular surface, which has certain influence on the appearance of the patient, and part of the patients have conflicted emotion to the operation.

In addition, dry eye is a common condition that occurs when tears do not provide adequate lubrication to the eye. Tears may be inadequate and unstable for a variety of reasons. For example, if tear secretion is insufficient or of low quality, dry eye may occur. This tear instability can lead to inflammation and damage to the ocular surface. The current mainstream method for treating xerophthalmia is to drop eyedrops, but the eyedrops have poor compliance and are difficult to be used by patients for a long time without omission. The prior art lacks an ocular surface drainage agent which can treat glaucoma diseases and dry eye diseases.

Disclosure of Invention

The invention provides an ocular surface drainage object, which solves the problem that the prior art lacks an ocular surface drainage object which can treat glaucoma diseases and dry eye diseases.

In order to solve the technical problems, the invention adopts a technical scheme that an eye surface drainage object is provided, which comprises a drainage inlet, a drainage outlet and a drainage channel arranged between the drainage inlet and the drainage outlet; the drainage inlet is used for inserting into the anterior chamber of the eye, and the drainage outlet is used for exposing the surface of the eye; also includes a fixation portion for engaging intraocular tissue.

Preferably, the middle part of the drainage channel is wound to form a disc-shaped drainage channel, and the disc-shaped drainage channel is used as the fixing part and is embedded between the conjunctiva and the sclera in the eye.

Preferably, the fixing part comprises two fixing pieces symmetrically arranged relative to the drainage channel.

Preferably, the ocular surface drainage is composed of a multi-layer polymer composite, wherein a flow channel is disposed in the multi-layer polymer.

Preferably, the drainage inlet is provided with an inclined section, and an included angle between the inclined section and the axis of the drainage channel is 30-45 degrees.

Preferably, the cross section of the drainage channel is circular, the inner diameter range of the drainage channel is 0.04 mm-0.1 mm, and the outer diameter range of the drainage channel is 0.25 mm-0.35 mm.

Preferably, the drainage channel further comprises a near-end drainage channel and a far-end drainage channel which are perpendicular to each other, one end of the disc-shaped drainage channel is connected with the near-end drainage channel, and the other end of the disc-shaped drainage channel is connected with the far-end drainage channel.

Preferably, the drainage channel is linear.

Preferably, the polymers in the plurality of layers are respectively a top layer polymer, a middle layer polymer and a bottom layer polymer, and the drainage channel is formed by combining the top layer polymer, the middle layer polymer and the bottom layer polymer together.

Preferably, the ocular surface drainage is made of a hydrophobic material.

The invention has the beneficial effects that: the invention discloses an eye surface drainage object, which comprises a drainage inlet, a drainage outlet and a drainage channel arranged between the drainage inlet and the drainage outlet; the drainage inlet is used for inserting into the anterior chamber of the eye, and the drainage outlet is used for exposing the surface of the eye; also comprises a fixing part used for combining with the intraocular tissue. In the invention, the ocular surface drainage can establish an artificial drainage channel from the anterior chamber to the ocular surface, drain aqueous humor in eyes, reduce intraocular pressure and treat glaucoma; meanwhile, the liquid in the anterior chamber can be drained to the ocular surface to treat xerophthalmia. The fixing part and the intraocular tissues grow together, and when the eyes are squeezed or collided by external force, the ocular surface drainage can not be displaced; the drainage outlet of the ocular surface drainage matter is far away from the conjunctiva wound, so that the blockage of the tube can not occur. And the volume is small, the wound on the eye is small, the eye is quickly healed, the filtering bubble is not generated, and the appearance of the patient is not influenced.

Drawings

FIG. 1 is a front view of one embodiment of an ocular surface drainage device according to the present invention;

FIG. 2 is a perspective view of one embodiment of an ocular drainage device according to the present invention;

FIG. 3 is a side view of one embodiment of an ocular surface drainage device according to the present invention;

FIG. 4 is a schematic illustration of the laminar flow of an ocular surface drainage in draining aqueous humor according to the present invention;

FIG. 5 is a schematic view of the force distribution of the inner wall of an ocular surface drainage system for draining aqueous humor in accordance with the present invention;

FIG. 6 is an enlarged schematic view of area A of FIG. 3;

FIG. 7 is a schematic flow diagram of an ocular surface drainage during implantation in accordance with the present invention;

FIG. 8 is another schematic flow diagram of an ocular surface drainage during implantation in accordance with the present invention;

FIG. 9 is another schematic flow diagram of an ocular surface drainage during implantation in accordance with the present invention;

FIG. 10 is an elevation view of one embodiment of an ocular surface drainage device according to the present invention;

fig. 11 is a perspective view of an embodiment of an ocular surface drainage device according to the present invention;

FIG. 12 is another schematic flow diagram of an ocular surface drainage during implantation in accordance with the present invention;

FIG. 13 is an elevation view of one embodiment of an ocular surface drainage device according to the present invention;

FIG. 14 is a perspective view of one embodiment of an ocular surface drainage device according to the present invention;

FIG. 15 is an exploded view of one embodiment of an ocular surface drainage device according to the present invention;

fig. 16 is another exploded view of an embodiment of an ocular surface drainage device according to the present invention.

Detailed Description

In order to facilitate an understanding of the invention, reference will now be made in detail to the present embodiments of the invention, examples of which are illustrated in the accompanying drawings. Preferred embodiments of the present invention are shown in the drawings. This invention may, however, be embodied in many different forms and should not be construed as limited to the embodiments set forth herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete.

It is to be noted that, unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. The terminology used in the description of the invention herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. As used herein, the term "and/or" includes any and all combinations of one or more of the associated listed items.

The invention provides an ocular surface drainage object, which establishes a drainage path of an anterior chamber and an ocular surface, aqueous humor is directly drained to the ocular surface through the ocular surface drainage object under the action of anterior chamber pressure, the intraocular pressure reducing effect is determined by the ocular surface drainage object, the ocular surface drainage object is not influenced by blocking schlemms tubes in eyes, and the cicatrization drainage effect and the appearance are not generated.

The ocular surface drainage product can be used for treating glaucoma and dry eye. After aqueous humor is drained to the ocular surface, the aqueous humor is uniformly distributed on the ocular surface through opening and closing of the eyelids. The lacrimation of the patient with xerophthalmia is insufficient, and the drained aqueous humor can be used as a good supplement.

The ocular surface drainage comprises a drainage inlet 101 and a drainage outlet 102, and a drainage channel 1 disposed between the drainage inlet 101 and the drainage outlet 102; a drainage inlet 101 for insertion into the anterior chamber of the eye and a drainage outlet 102 for exposure of the ocular surface; also included is a fixation portion for engaging tissue within the eye, the fixation portion preferably being fixed between the conjunctiva and the sclera.

The ocular surface drainage matter is inserted into the anterior chamber of the eye through the drainage inlet 101 of the ocular surface drainage matter in an operation mode, the fixing part is embedded between the conjunctiva and the sclera, and the fixing part and the tissue in the middle area of the conjunctiva and the sclera grow together after the ocular surface drainage matter is implanted into the eye due to the strong regeneration capacity of the conjunctiva and the sclera, so that the fixation of the ocular surface drainage matter is realized, and when the eye is extruded or collided by external force, the ocular surface drainage matter can not be displaced; the drainage port 102 exposes the ocular surface.

After the ocular surface drainage implant is implanted, the aqueous humor in the anterior chamber of the eye flows to the ocular surface through the drainage inlet 101, the drainage channel 1 and the drainage outlet 102 in sequence, so that the artificial channel from the anterior chamber to the ocular surface is established, and the aqueous humor flows into the tear film of the eye through the ocular surface drainage implant under the action of the intraocular pressure, so that the glaucoma and the dry eye can be treated.

Preferably, as an embodiment of the ocular surface drainage, as shown in fig. 1 to 3, the ocular surface drainage is tubular, and comprises a drainage inlet 101 and a drainage outlet 102, and a drainage channel 1 is arranged between the drainage inlet 101 and the drainage outlet 102; the drainage channel 1 comprises a near-end drainage channel 2, a disc-shaped drainage channel 3 and a far-end drainage channel 4 which are connected in sequence. The near-end drainage channel 2 and the far-end drainage channel 3 are mutually vertical and are both linear; one end of the disc-shaped drainage channel 3 is connected with the near-end drainage channel 2, and the other end is connected with the far-end drainage channel 4.

It can be seen that the middle part of the drainage channel 1 is wound to form a disc-shaped drainage channel 3, and the disc-shaped drainage channel 3 is positioned on the same plane as the distal drainage channel 4 except for the joint part with the proximal drainage channel 2. And the disc-shaped drainage channel 3 serves as a fixing part for embedding between the conjunctiva and the sclera in the eye.

Preferably, the cross section of the drainage channel 1 can be circular (both the inner surface and the outer surface are circular), and the inner surface of the cross section of the drainage channel 1 refers to a section through which aqueous humor flows; the cross section of the drainage channel 1 can also be a hollow rectangle (preferably, the inner surface is circular, and the outer surface can be square or rectangular), a hollow triangle (preferably, the inner surface is circular and the outer surface is regular triangle), and a hollow ellipse (preferably, the inner surface is circular and the outer surface is elliptical).

In fig. 1 to 3, the cross section of the drainage channel 1 is circular ring shape, the inner diameter range is 0.04mm to 0.1mm, and the outer diameter range is 0.25mm to 0.35mm.

Further, the inner diameter of the drainage channel 1 is sufficiently small, and the aqueous humor flows out in a laminar state, which conforms to Poiseuille's equation,

wherein Q is the rate of aqueous humor production in the human eye; Δ P is the pressure difference between the drainage inlet 101 and the drainage outlet 102, and since the drainage outlet 102 is located at the ocular surface and the pressure is 0, Δ P is the intraocular pressure; r is the radius of the inner channel of the drainage channel 1; η is the viscosity coefficient of the aqueous humor; l is the length of the drainage channel 1. Where Q and eta are constants, so that Δ P can be controlled by adjusting r and l. Different Δ Ρ can be obtained by adjusting r and l, and desired postoperative intraocular pressure can be obtained for early, middle and late glaucoma using ocular surface drains of different specifications.

In one embodiment, when the inner diameter of the drainage channel 1 is 0.08mm and the total length of the drainage channel 1 is 46mm, the intraocular pressure Δ P can be controlled to be 10mmHg. The length of the near-end drainage channel 2 is 8mm, the length of the far-end drainage channel 3 is 4mm, and the longitudinal height of the disc-shaped drainage channel 3 is 3mm. When the intraocular pressure delta P is more than 10mmHg, the aqueous humor flows out to the ocular surface under the action of pressure to play a role in reducing intraocular pressure; when the intraocular pressure delta P is less than or equal to 10mmHg, the flow of the aqueous humor stops, and the generation of hypotony is prevented.

Further, aqueous humor is a newtonian fluid, and the following 4 conditions are satisfied:

1. the liquid is incompressible;

2. the flow is an isothermal process;

3. the liquid can not slide on the wall surface of the pipeline;

4. the viscosity of the liquid does not change with time.

Referring to fig. 4 and 5, in fig. 4, when the ocular surface drainage drains aqueous humor, the flow of aqueous humor in the drainage channel 1 is laminar, which conforms to the laminar flow of newtonian fluid inside a simple round tube. In fig. 5, it can be known from the force analysis that the slower the flow speed of the liquid and the larger the shear stress τ as the fluid gets closer to the pipe wall, which conforms to the force distribution of the newtonian fluid inside a simple circular pipe. And the shear stress tau is in accordance with

Δ P is the intraocular pressure, r is the radius of the inner channel of drainage channel 1, and l is the length of drainage channel 1.

Therefore, when the shear stress τ at the tube wall is greater than the adhesion of proteins or cells, proteins and bacteria will be washed out of the body and will not be adsorbed on the tube wall, causing blockage or infection.

Preferably, as shown in fig. 6, the drainage inlet 101 has an oblique cross-section to facilitate the penetration of the sclera into the anterior chamber during the operation of the surgeon, and the angle α between the oblique cross-section and the axis 103 of the drainage channel 1 is 30 ° to 45 °. Specifically, axis 103 is the axis of the proximal drainage channel 2.

Preferably, the drainage inlet 101 may also be of a right cross-section perpendicular to the axis 103.

Preferably, the drainage outlet 102 has a positive cross-section perpendicular to the axis of the distal drainage channel 4, although the drainage outlet 102 may have an oblique cross-section.

Preferably, in fig. 1 to 3, the overall shape of the disc-shaped drainage channel 3 is similar to that of a playground runway, and is an ellipse with semicircular ends and rectangular middle, so that the total length of the drainage channel 1 can be adjusted by adjusting the rectangular length in the middle of the disc-shaped drainage channel 3 on the premise of keeping the length of the proximal drainage channel 2, the length of the distal drainage channel 4 and the longitudinal height of the disc-shaped drainage channel 3 unchanged.

Preferably, the shape of the disc-shaped drainage channel 3 may also be circular, square, rectangular, etc.

Preferably, the ocular surface drainage is made of a hydrophobic material, has a smooth surface and a low coefficient of friction. The hydrophobic material may be SIBS, nylon, TPU, PEBAX, PI, PTFE, etc., or a material modified to obtain hydrophobic properties. When the ocular surface drainage material is implanted into eyes, the inner surface of the ocular surface drainage material is smooth and is not easy to adhere to in-vivo protein and endothelial cells, and the channel through which aqueous humor flows is not easy to block. The outer surface of the ocular surface drainage is smooth, the adhesion of bacteria is poor, and the propagation of bacteria is not facilitated.

Preferably, the ocular surface drainage is made of a thermoplastic material, or a material that is both hydrophobic and thermoplastic. Winding a catheter on a special shaping tool at room temperature for fixing, putting the catheter in an oven for heating, taking out the catheter and cooling to obtain the ocular surface drainage object with the shape.

Further, with reference to fig. 7 to 9, the step of implanting the ocular surface drainage into the eye is as follows:

step 1: injecting anesthetic to fix the eyeball 100;

and 2, step: using a conjunctiva mark pen M to draw two marker points which are 3mm apart 4mm below the limbus;

and 3, step 3: performing conjunctival cutting along the straight track L;

and 4, step 4: separating the conjunctiva and sclera downward from the incision using a blunt scissors; a conjunctival wound K is generated in the process;

and 5: inserting a 23G blunt needle into a drainage outlet of an ocular surface drainage object, and injecting normal saline until continuous normal saline flows out from the drainage inlet;

step 6: using a 25G needle to penetrate the sclera, establishing a subcutaneous tunnel up to the anterior chamber;

and 7: the proximal drainage channel 2 of the ocular surface drainage enters the anterior chamber along the subcutaneous tunnel, and the drainage inlet 101 enters the anterior chamber for 2mm; the disc-shaped drainage channel 3 is placed between the conjunctiva and the sclera, and a drainage outlet 102 at the tail end of the distal drainage channel 4 is left on the ocular surface;

and step 8: the conjunctiva is sutured, and the operation is completed.

With reference to fig. 7, the distal drainage channel 4 is located on the lower eyelid, a larger space is provided for accommodating the distal drainage channel 4, the distance between the conjunctiva wound K and the drainage outlet 102 at the end of the distal drainage channel 4 is about 3mm, so that the secretion on the conjunctiva wound K is prevented from blocking the tube, the drainage outlet 102 is connected with the tear film, and the drained aqueous humor can be directly blended into the tear film. It can be seen that the ocular surface drainage has the following characteristics:

first, ocular surface drains can create an artificial drainage channel from the anterior chamber to the ocular surface, drain aqueous humor in the eye, lower intraocular pressure, and treat glaucoma.

Secondly, the ocular surface drainage matter can drain the liquid in the anterior chamber to the ocular surface at the same time to treat xerophthalmia, and the ocular surface drainage matter can be implanted at one time to drain aqueous humor continuously and moisten the ocular surface, thereby overcoming the problem of poor compliance of eye drop treatment xerophthalmia.

Third, the ocular surface drainage can be firmly fixed without falling off or shifting.

Fourth, the drainage outlet 102 of the ocular surface drainage is far from the conjunctival wound K, so that the blockage of the tube does not occur.

Fifthly, the volume of the ocular surface drainage is small, the trauma to the eyes in the surgical implantation process is small, and the eyes heal quickly.

Sixthly, the eyeball does not generate filtering bleb after being implanted, the appearance of a patient is not influenced, and the drainage is not limited by the function of the filtering bleb.

Further, as a second embodiment of the ocular surface drainage, as shown in fig. 8 and 9, the ocular surface drainage has a tubular shape, and comprises a drainage inlet 101 and a drainage outlet 102, a drainage channel 1 is arranged between the drainage inlet and the drainage outlet, and the drainage channel 1 is a linear type.

In this embodiment, the fixation section is located near the outflow port 102 for embedding between the conjunctiva and sclera in the eye. The fixing part comprises two fixing pieces 5 which are symmetrically arranged relative to the drainage channel 1; the fixing piece 5 is provided with a fixing hole 501, the fixing part and the tissues in the eyes grow together, the tissues in the eyes can pass through the fixing hole 501 in the growth process, the stability of the ocular surface drainage object is further improved, and when the eyes are squeezed or collided by external force, the ocular surface drainage object cannot be displaced.

Preferably, in this embodiment, the fixing portion and the drainage channel 1 are connected in the following manner: the fixing part and the drainage channel 1 are integrally formed by injection molding, medical suture, stainless steel wires, nickel titanium wires and the like are used as a mandrel, and after the ocular surface drainage object is formed by injection molding, the mandrel is pulled out to obtain the desired outer diameter of the drainage channel 1. Alternatively, the fixing portion is bonded to the drainage channel 1 by using a thin silicone sheet, for example, liquid silicone is introduced into a mold, the drainage channel 1 is placed, and after the liquid silicone is cured, the cured silicone is cut by using a cutter or laser, so as to obtain the shape of the fixing piece 5 to be obtained.

In one embodiment, the inner diameter of drainage channel 1 is 0.05mm, the total length of drainage channel 1 is 7.1mm, and the intraocular pressure can be controlled at 10mmHg. When the intraocular pressure is more than 10mmHg, the aqueous humor flows out to the ocular surface under the pressure effect to play a role in reducing the intraocular pressure; when the intraocular pressure is less than or equal to 10mmHg, the flow of aqueous humor is stopped, and the generation of low intraocular pressure is prevented.

Further, with reference to fig. 12, the step of implanting the ocular surface drainage implant into the eye is as follows:

step 1: injecting anesthetic to fix the eyeball 100;

and 2, step: using a conjunctiva mark pen M to draw two marker points which are 3mm apart 4mm below the limbus;

and step 3: performing conjunctival cutting along the straight track L;

and 4, step 4: separating the conjunctiva and sclera downward from the incision using a blunt scissors; a conjunctival wound K is generated in the process;

and 5: inserting a 23G blunt needle into a drainage outlet of an ocular surface drainage object, and injecting normal saline until continuous normal saline flows out from the drainage inlet;

and 6: using a 25G needle to penetrate the sclera, creating a subcutaneous tunnel through to the anterior chamber;

and 7: the drainage inlet of the ocular surface drainage enters the anterior chamber for 2mm; the fixed part is placed between the conjunctiva and the sclera, and a drainage outlet of the ocular surface drainage matter is remained on the ocular surface;

and step 8: the conjunctiva is sutured, and the operation is completed.

In this embodiment, according to the equation of Poiseuille (Poiseuille), if the intraocular pressure is small, the disc-shaped drainage channel 3 in the first embodiment can be omitted, and a linear type ocular surface drainage can be directly used, and the fixation can be performed by the fixation portion.

Further, the same or reference contents (such as the oblique section of the drainage inlet 101, the material of the drainage channel 1, etc.) as those of the first embodiment are not repeated herein, please refer to the first embodiment.

Further, as a third embodiment of the present invention, fig. 12 to 15 are shown.

The ocular surface drainage is flat and comprises a drainage inlet 101, a drainage outlet 102 and a drainage channel 1 arranged between the drainage inlet 101 and the drainage outlet 102. A drainage inlet 101 for insertion into the anterior chamber of the eye and a drainage outlet 102 for exposure of the ocular surface; also comprises a fixing part used for combining with the intraocular tissue.

The drainage channel 1 comprises a near-end drainage part 6, a disc-shaped drainage part 7 and a far-end drainage part 8, wherein the near-end drainage part 6 and the far-end drainage part 8 are mutually vertical and are linear; one end of the disc-shaped drainage part 7 is connected with the near-end drainage part 6, and the other end is connected with the far-end drainage part 8. In the present embodiment, the disk-shaped drainage portion 7 serves as the fixing portion for embedding between the conjunctiva and the sclera in the eye.

Further, as shown in fig. 14 and 15, the ocular surface drainage is composed of a multi-layer polymer composite with flow channels disposed therein.

The multi-layer polymers are a top layer polymer 9, a middle layer polymer 10 and a bottom layer polymer 11, respectively. The drainage channel 1 is formed by the top layer polymer 9, the middle layer polymer 10 and the bottom layer polymer 10 which are combined together. Every layer of polymer all includes near-end bar drainage portion 12, middle dish type connecting portion 13, distal end bar drainage portion 14, and near-end bar drainage portion 13 and distal end bar drainage portion 14 all are connected with middle dish type connecting portion 13 to mutually perpendicular.

Further, a first linear flow channel 15 is arranged on the lower surface of the top polymer 9 (the surface of the top polymer 9 close to the middle polymer 10 is the lower surface), and the first linear flow channel 15 extends from the end of the proximal strip-shaped drainage part 12 of the top polymer 9 to the direction of the middle disc type connecting part 13; the first linear flow channel 15 is a channel-shaped flow channel and does not penetrate through the top polymer 9.

Further, a disk-shaped flow channel 16 and a second linear flow channel 17 are provided through the interlayer polymer 10. The disc-shaped flow channel 16 is positioned in the area of the middle disc-shaped connecting part 13 of the middle layer polymer 10, and the second straight-type flow channel 17 extends from the end of the distal strip-shaped drainage part 14 of the middle layer polymer 10 towards the direction of the middle disc-shaped connecting part 13 and is communicated with the disc-shaped flow channel 16. After the top layer polymer 9, the middle layer polymer 10 and the bottom layer polymer 11 are compounded and molded, the first linear flow channel 15 is communicated with the disc-shaped flow channel 16, the upper surface of the middle layer polymer 10 is used for closing the first linear flow channel 15, and the lower surface of the top layer polymer 9 and the upper surface of the bottom layer polymer 11 are used for closing the disc-shaped flow channel 16 and the second linear flow channel 17.

Preferably, the multilayer polymer composite also comprises only two layers of the top layer polymer 9 and the bottom layer polymer 11, a disc-shaped flow channel 16 and a second straight-line-shaped flow channel 17 are arranged on the middle layer polymer 10 in a penetrating way, and the disc-shaped flow channel 16 and the second straight-line-shaped flow channel 17 are both groove-shaped flow channels and do not penetrate through the bottom layer polymer 11.

Further, the same or reference contents (for example, the oblique section of the drainage inlet 101, the material of the drainage channel 1, etc.) as those of the first embodiment are not repeated herein, please refer to the first embodiment.

Therefore, the invention discloses an eye surface drainage object, which comprises a drainage inlet, a drainage outlet and a drainage channel arranged between the drainage inlet and the drainage outlet; the drainage inlet is used for being inserted into the anterior chamber of the eye, and the drainage outlet is used for exposing the surface of the eye; also includes a fixation portion for engaging intraocular tissue. In the invention, the ocular surface drainage can establish an artificial drainage channel from the anterior chamber to the ocular surface, drain aqueous humor in eyes, reduce intraocular pressure and treat glaucoma; meanwhile, the liquid in the anterior chamber can be drained to the ocular surface, and the xerophthalmia is treated. The fixing part and the intraocular tissues grow together, and when the eyes are squeezed or collided by external force, the ocular surface drainage can not be displaced; the drainage outlet of the ocular surface drainage matter is far away from the conjunctiva wound, so that the blockage of the tube can not occur. And the eye patch is small in size, small in wound caused to eyes, fast in eye healing, free of filter bubble and free of influence on appearance of a patient.

The above description is only an embodiment of the present invention, and not intended to limit the scope of the present invention, and all equivalent structural changes made by using the contents of the present specification and the drawings, or applied directly or indirectly to other related technical fields, are included in the scope of the present invention.

Claims (10)

1. An ocular surface drainage device, comprising: comprises a drainage inlet, a drainage outlet and a drainage channel arranged between the drainage inlet and the drainage outlet; the drainage inlet is used for inserting into the anterior chamber of the eye, and the drainage outlet is used for exposing the surface of the eye; also includes a fixation portion for engaging intraocular tissue.

2. The ocular surface drainage of claim 1, wherein: the middle part of the drainage channel is wound to form a disc-shaped drainage channel which is used as the fixing part and is embedded between a conjunctiva and a sclera in an eye.

3. The ocular surface drainage of claim 1, wherein: the fixing part comprises two fixing pieces which are symmetrically arranged relative to the drainage channel.

4. The ocular surface drainage of claim 1, wherein: the ocular surface drainage material is composed of a plurality of layers of polymer composites, and a flow channel is arranged on the plurality of layers of polymer.

5. The ocular surface drainage of claim 1, wherein: the drainage inlet is provided with an inclined section, and an included angle between the inclined section and the axis of the drainage channel is 30-45 degrees.

6. The ocular surface drainage device of claim 2, wherein: the cross section of the drainage channel is circular, the inner diameter range of the drainage channel is 0.04 mm-0.1 mm, and the outer diameter range of the drainage channel is 0.25 mm-0.35 mm.

7. The ocular surface drainage of claim 6, wherein: the drainage channel further comprises a near-end drainage channel and a far-end drainage channel which are perpendicular to each other, one end of the disc-shaped drainage channel is connected with the near-end drainage channel, and the other end of the disc-shaped drainage channel is connected with the far-end drainage channel.

8. The ocular surface drainage of claim 3, wherein: the drainage channel is linear.

9. The ocular surface drainage of claim 4, wherein: the polymers in multiple layers are respectively a top layer polymer, a middle layer polymer and a bottom layer polymer, and the drainage channel is formed by combining the top layer polymer, the middle layer polymer and the bottom layer polymer together.

10. The ocular surface drainage of any of claims 1-9, wherein: the ocular surface drainage is made of a hydrophobic material.

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