CN115581447B - Intelligent calibration device for performance of solid pressure measuring catheter and calibration method thereof - Google Patents

Intelligent calibration device for performance of solid pressure measuring catheter and calibration method thereof Download PDF

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Publication number
CN115581447B
CN115581447B CN202211228348.7A CN202211228348A CN115581447B CN 115581447 B CN115581447 B CN 115581447B CN 202211228348 A CN202211228348 A CN 202211228348A CN 115581447 B CN115581447 B CN 115581447B
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pressure
temperature
calibration
cavity
solid
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CN115581447A (en
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麻利义
何居刚
朱潮军
虞将栋
陈建峰
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MEDKINETIC Inc
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MEDKINETIC Inc
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/03Detecting, measuring or recording fluid pressure within the body other than blood pressure, e.g. cerebral pressure; Measuring pressure in body tissues or organs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2560/00Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
    • A61B2560/02Operational features
    • A61B2560/0223Operational features of calibration, e.g. protocols for calibrating sensors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2560/00Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
    • A61B2560/02Operational features
    • A61B2560/0242Operational features adapted to measure environmental factors, e.g. temperature, pollution
    • A61B2560/0247Operational features adapted to measure environmental factors, e.g. temperature, pollution for compensation or correction of the measured physiological value
    • A61B2560/0252Operational features adapted to measure environmental factors, e.g. temperature, pollution for compensation or correction of the measured physiological value using ambient temperature

Abstract

The invention discloses an intelligent calibration device and a calibration method for the performance of a solid pressure measuring catheter, wherein the intelligent calibration method for the performance of the solid pressure measuring catheter comprises the following steps of S1: the control circuit board receives the pressure calibration instruction transmitted by the upper computer, so that the control circuit board respectively controls and adjusts the pressurizing air pump and the electromagnetic valve to enable the cavity for placing the solid pressure measuring catheter to be stable at constant pressure, and the automatic pressure calibration of the solid pressure measuring catheter is completed. The invention discloses an intelligent calibration device for the performance of a solid pressure measuring catheter and a calibration method thereof, which are used for rapidly calibrating the pressure characteristics of the solid pressure measuring catheter, including pressure linearity and temperature linearity, and only the solid pressure measuring catheter to be calibrated is required to be sealed into the device, so that the device can intelligently complete the calibration functions of the pressure linearity and the temperature linearity.

Description

Intelligent calibration device for performance of solid pressure measuring catheter and calibration method thereof
Technical Field
The invention belongs to the technical field of solid pressure measurement catheter calibration, and particularly relates to an intelligent calibration device and an intelligent calibration method for solid pressure measurement catheter performance
Background
Gastrointestinal functional disorders, which account for about 40% of patients who are clinically treated in the gastroenterology department, include gastroesophageal reflux disease, achalasia of the cardia, constipation, diarrhea, fecal incontinence, and the like. Scientific and accurate diagnosis is important for the treatment of gastrointestinal functional diseases, and gut manometry is considered to be the gold standard for diagnosing such diseases, esophageal manometry and anorectal manometry, respectively.
With the development of science, technology and economy, such examinations have been commonly applied to various clinical institutions. Currently, two pressure measuring modes are mainly available in the market, namely water perfusion pressure measuring and solid state pressure measuring. The water filling pressure measurement is that a water filling pressure measurement catheter is connected with an external pressure sensor, and the water filling pressure measurement catheter is cheap, but is influenced by other factors, such as bubbles, water pressure and the like, during detection due to the limitations of the catheter aperture and the technology. So the preparation of the device before operation is complex, and the pressure measurement result is also deeply affected by the instability of the air bubble. The solid pressure measuring catheter is provided with a built-in pressure sensor, and the precision and the quantity of the solid pressure measuring catheter exceed those of the water filling pressure measuring catheter. The solid pressure catheter will replace the water perfusion pressure measurement in future pressure measurement clinical applications. The built-in pressure sensor of the solid pressure measuring catheter is processed by adopting a diffusion silicon chip, and the pressure performance and the temperature performance of the catheter need to be corrected regularly before delivery or in the use process.
The existing solid pressure measurement catheter performance calibration needs special pressurizing and heating constant temperature equipment, and the calibration mode is to realize pressure linearity by manual pressurization and temperature linearity by switching high-temperature water back and forth, so that the calibration process is very complicated, the operation process is complex and cumbersome, and the operation of doctors is inconvenient.
Accordingly, the above problems are further improved.
Disclosure of Invention
The invention mainly aims to provide an intelligent calibration device and a calibration method thereof for the performance of a solid pressure measuring catheter, which are used for rapidly calibrating the pressure characteristics of the solid pressure measuring catheter, including pressure linearity and temperature linearity, and only the solid pressure measuring catheter to be calibrated is required to be sealed into the device, and the device can intelligently complete the calibration functions of the pressure linearity and the temperature linearity.
In order to achieve the above object, the present invention provides an intelligent calibration method for performance of a solid pressure measurement catheter, for pressure automatic calibration and temperature automatic compensation calibration of the solid pressure measurement catheter, comprising the steps of:
step S1: the control circuit board receives a pressure calibration instruction transmitted by the upper computer, so that the control circuit board respectively controls and adjusts the pressurizing air pump and the electromagnetic valve to enable the cavity for placing the solid pressure measuring catheter to be stable at constant pressure, and the automatic pressure calibration of the solid pressure measuring catheter is completed;
Step S2: after the automatic calibration of the pressure of the solid pressure measuring catheter is completed, the upper computer automatically transmits a temperature compensation calibration instruction to the control circuit board, so that the control circuit board respectively controls and adjusts the circulating fan and the surrounding heating conductor, and the cavity for placing the solid pressure measuring catheter is stabilized at a constant temperature, thereby completing the automatic calibration of the temperature compensation of the solid pressure measuring catheter.
As a further preferable embodiment of the above embodiment, step S1 includes the steps of:
step S1.1: the control circuit board receives a first pressure calibration instruction transmitted by the upper computer, closes the electromagnetic valve, and starts the pressurizing air pump to inflate and pressurize the cavity;
step S1.2: the pressure sensor arranged in the cavity is communicated with the interior of the cavity, so that the pressure sensor measures the internal environmental pressure change of the cavity in real time and transmits a pressure signal obtained by detection to the control circuit board, (after the pressure is applied to a certain degree), the control circuit board adjusts the air inlet of the pressurizing air pump and the air outlet of the electromagnetic valve according to a first pressure calibration instruction transmitted by the upper computer, so that the internal pressure of the cavity is automatically adjusted to a first calibration pressure (preferably 5kPa plus or minus 0.1 kPa) matched with the first pressure calibration instruction and a first pressure signal V1 is displayed in real time through the pressure sensor (the upper computer), and then the cavity is continuously stabilized for a first time (preferably 10 seconds);
Step S1.3: performing pressure zero setting treatment on pressure sensors of all channels of the solid pressure measuring guide pipe after the first time of continuous pressure stabilization (the solid pressure measuring guide pipe is provided with n signal recording channels, each signal recording channel is provided with a built-in diffusion silicon pressure sensor, before calibration, the initial pressure value of the pressure sensor of each channel is different, for example, the initial pressure value of the pressure sensor of the first channel is 1kPa, the initial pressure value of the pressure sensor of the second channel is 1.5kPa, at the moment, the pressure value of a cavity rises by 5kPa, then one upper computer is displayed as 6kPa, one upper computer is displayed as 6.5kPa, so that data is not uniform, thereby subtracting 6kPa from the pressure sensor of the first channel, subtracting 6.5kPa from the pressure sensor of the second channel, and performing zero setting treatment (the pressure sensors of the other channels are also subjected to zero setting treatment) so that 0kPa are displayed on the upper computer, so that data which are easier to read in the subsequent step-up process are acquired, and a circuit board is also arranged for realizing sampling, analog-digital conversion and data transmission of the pressure sensor of each channel and data transmission to the upper computer and calibration parameters of the pressure sensor of each channel, and calibration parameters of the pressure sensor are stored at the same time;
Step S1.4: the control circuit board adjusts the air inlet of the pressurizing air pump and the air outlet of the electromagnetic valve through a second pressure calibration command transmitted by the upper computer, so that the internal pressure of the cavity is automatically adjusted to a second calibration pressure (preferably 50kPa plus or minus 0.1 kPa) matched with the second pressure calibration command, a second pressure signal V2 is displayed in real time through a pressure sensor (the upper computer) arranged in the cavity, and then the cavity is continuously stabilized for a second time (preferably 10 seconds);
step S1.5: the upper computer obtains the pressure output value Pn of each channel through a plurality of pressure sensors of the solid pressure measuring catheter, and calculates the pressure linearity after meeting the condition that the pressure output value Pn of each channel is positioned in a preset pressure range (45 kPa plus or minus 0.1 kPa) through the following formula:
Kn1=Pn/(V2-V1);
kn1 represents the pressure linear coefficient of the first nth channel, pn represents the pressure value of the nth channel (nth pressure channel, n is 1,2, 3.) when the solid state pressure measuring catheter is at the second pressure signal V2;
then, carrying out regression calculation and pressure compensation on the output of the pressure sensors of all the channels through Kn1, so that the output pressure output values of the pressure sensors of all the channels are consistent when the pressure changes are detected, and further, single pressure calibration is completed;
Step S1.6: after the single pressure calibration is successful, the control circuit board controls the electromagnetic valve to deflate and re-executes the step S1.4 and the step S1.5 twice (preferably twice, the specific times can be set according to actual demands), so as to obtain the pressure linear coefficient Kn2 of each channel of the second time and the pressure linear coefficient Kn3 of each channel of the third time, the pressure calibration linear coefficients of each channel of the solid pressure measuring catheter are obtained through average calculation according to the following formula, and are written into a circuit board storage area of the solid pressure measuring catheter (an upper computer is simultaneously connected with the control circuit board and the circuit board of the solid pressure measuring catheter, so that the pressure value of a cavity and the pressure value of each channel are obtained, so that the related pressure linear coefficients are obtained through calculation by the upper computer, and finally, the accurate pressure linear coefficients are written into the circuit board storage area of the solid pressure measuring catheter, so that the pressure values output by the pressure sensors of each channel after compensation are kept consistent when the solid pressure measuring catheter is actually used):
Kave=(Kn1+Kn2+Kn3)/3。
as a further preferable embodiment of the above embodiment, step S2 includes the steps of:
step S2.1: the control circuit board receives a first temperature compensation calibration instruction transmitted by the upper computer, then closes the electromagnetic valve and the pressurizing air pump, and starts the circulating fan and the surrounding heating conductor;
Step S2.2: the method comprises the steps that a surrounding heating conductor which surrounds a cavity for heating is divided into a plurality of sections of heating units (including continuous and discontinuous), each section of heating unit can be independently heated, each section of heating unit is provided with a temperature sensor in a matching mode (the number of the heating units is matched with that of the temperature sensors), and each temperature sensor is communicated with the inside of the cavity, so that the temperature sensor measures the internal temperature change of the corresponding cavity (each area) of each section of heating unit in real time, and temperature signals obtained through detection are transmitted to an upper computer through a control circuit board, and are displayed respectively by the upper computer;
step S2.3: monitoring the temperature balance of the cavity through each temperature sensor, and realizing internal temperature adjustment by combining a circulating fan (accelerating temperature balance adjustment) with a surrounding heating conductor, so that the heating temperature of each section of heating unit for each region of the cavity reaches an initial temperature value (30+/-0.5 ℃) matched with a first temperature compensation calibration instruction and is within a preset temperature difference range (preferably 0.1 ℃, if the temperature of which region of the cavity is greater than the temperature of other regions by a preset temperature difference, only the heating temperature of the heating unit corresponding to the region needs to be adjusted), and after the initial temperature value is reached, the control circuit board automatically adjusts the heating temperature of the surrounding heating conductor to realize initial temperature constant, and constant temperature is realized in the cavity for a third time (preferably 2 minutes);
Step S2.4: setting the temperature obtained by the temperature sensor to be T1..Tn, calculating an average value by a formula of Tave 1= (T1+T2..Tn)/n, so as to obtain a temperature value Tave1, wherein the error between Tave1 and the actual set temperature is the constant effective temperature of the current cavity body temperature within a preset value (less than or equal to 0.1 ℃), and carrying out pressure zero setting on the pressure sensors of all channels of the solid side pressure conduit at the moment, otherwise, the cavity continuously carries out constant temperature treatment (the actual current temperature zero setting is more convenient for detection in the subsequent temperature rising process) through a control circuit board;
step S2.5: after the pressure is set to zero, the control circuit board adjusts the circulating fan and the surrounding heating conductor through a second temperature compensation calibration command transmitted by the upper computer, so that the internal temperature of the cavity is automatically adjusted to a second temperature value (preferably 40+/-0.5 ℃ and a calibration point is added in the process of increasing the temperature of the cavity according to a step length of 0.5 or 1 ℃) which is equal to the second temperature value, the heating temperature of the surrounding heating conductor is gradually reduced in the process of continuously increasing the temperature, when the temperature exceeds the second temperature value, the control circuit board starts the pressurizing air pump to suck external low-temperature gas, the electromagnetic valve is started to keep the pressure balance in the cavity, and the second temperature value of the cavity is gradually balanced, and in the process of rising from the initial temperature to the second temperature, rising from the initial temperature by a step length of DeltaT, (wherein DeltaT=0.5 ℃ or 1 ℃) is preferable, when the initial temperature rises by the first step length DeltaT, realizing constant temperature in the cavity for a third time (preferably 2 minutes), re-reading the temperature T1..Tn obtained by the temperature sensor, calculating an average value by a formula Tave 2= (T1+T2..Tn)/n, so as to obtain a temperature value Tave2, wherein the error between Tave2 and the actual set temperature is the constant effective temperature of the current cavity body temperature within a preset value (less than or equal to 0.1 ℃), and simultaneously recording the pressure output values Pnt of all channels of the solid pressure measuring catheter, wherein Pnt represents the pressure value of an nth channel output by the solid pressure measuring catheter when the cavity temperature is T;
Step S2.6: after the temperature calibration of the first step length delta T is finished, heating is continued to the temperature area where the next step length delta T is positioned, so that the temperature is adjusted once when the temperature is measured at each step length, and the difference between the temperature area where the current step length is positioned and the temperature area where the adjacent previous step length is positioned is calculated, so as to obtain the pressure value Pnt output by each channel of the solid pressure measuring catheter after rising by delta T each time m Wherein t is m =T base +DeltaT×m, m is the number of steps, T base Initial calibration room temperature (i.e. Tave1 in step S2.4) up to the second temperature (and obtaining the pressure value Pnt of the last temperature segment) m ) All t will be acquired m Pnt corresponding to temperature section m The pressure values were fitted linearly three times to determine the curve equation:
y n =w 1 t 3 +w 2 t 2 +w 3 t+b;
then w is the coefficient in the formula 1 、w 2 、w 3 And b is written into a circuit board storage area of the solid pressure measuring catheter, y n The pressure value output by the nth channel pressure sensor when the temperature is at t ℃.
As a further preferable embodiment of the above embodiment, step S1 further includes:
step S0.2: the solid pressure measuring catheter vertically penetrates through the upper cover and is inserted into the cavity, the insertion depth is set to be that the solid pressure measuring catheter contains pressure sensor sections (the pressure sensors of all channels are arranged at different positions, so that the insertion depth of all channels is different), the length of the solid pressure measuring catheter is added with the preset distance (preferably 5 cm) depth position, and the upper cover is screwed down to enable the upper cover to be backlogged with the sealing ring so as to backlog the solid pressure measuring catheter, so that sealing is achieved.
As a further preferable embodiment of the above embodiment, step S0.2 further includes step S0.1: after each time the automatic calibration of temperature compensation is completed, the circuit board storage area of the solid state pressure measuring catheter acquires correction time information so as to set a time validity period according to the current correction time information, and judges whether the time validity period is in the next time when the solid state pressure measuring catheter is used, if so, the automatic calibration is not needed (including pressure and temperature calibration), otherwise, the automatic calibration is carried out.
As a further preferable technical solution of the above technical solution, in step S0.1, before each calibration of the solid state pressure measurement catheter (i.e. the time validity period has been exceeded), the upper computer and the control circuit board perform accuracy verification on the solid state pressure measurement catheter (i.e. judge the current accuracy by several tests of actual temperature and pressure), if the current accuracy is within the effective accuracy, the circuit board storage area automatically updates the time validity period according to the time of the current accuracy verification and does not need recalibration, otherwise, recalibration is performed automatically.
In order to achieve the above purpose, the invention also provides an intelligent calibration device for the performance of the solid pressure measuring catheter, which comprises a control circuit board, an upper computer, a pressurized air pump, an electromagnetic valve, a circulating fan and a surrounding heating conductor, wherein:
The control circuit board receives a pressure calibration instruction transmitted by the upper computer, so that the control circuit board respectively controls and adjusts the pressurizing air pump and the electromagnetic valve to enable the cavity for placing the solid pressure measuring catheter to be stable at constant pressure, and the automatic pressure calibration of the solid pressure measuring catheter is completed;
after the automatic calibration of the pressure of the solid pressure measuring catheter is completed, the upper computer automatically transmits a temperature compensation calibration instruction to the control circuit board, so that the control circuit board respectively controls and adjusts the circulating fan and the surrounding heating conductor, and the cavity for placing the solid pressure measuring catheter is stabilized at a constant temperature, thereby completing the automatic calibration of the temperature compensation of the solid pressure measuring catheter.
Drawings
FIG. 1 is a schematic diagram of an intelligent calibration device for solid state pressure catheter performance and a calibration method thereof according to the present invention.
Fig. 2 is a schematic structural view (cross-sectional view) of the intelligent calibration device for solid state pressure measurement catheter performance and its calibration method of the present invention.
The reference numerals include: 100. a housing; 200. a pressure calibration unit; 210. a pressure sensor; 220. a pressurized air pump; 230. an electromagnetic valve; 240. a one-way valve; 250. a connecting hose; 300. a temperature compensation unit; 310. a temperature sensor; 320. surrounding the heating conductor; 330. a circulation fan; 400. calibrating the cavity unit; 410. a cavity; 420. an upper cover; 430. a lower cover; 440. a seal ring; 500. a control circuit board; 600. an upper computer; 700. solid state pressure measuring catheter.
Detailed Description
The following description is presented to enable one of ordinary skill in the art to make and use the invention. The preferred embodiments in the following description are by way of example only and other obvious variations will occur to those skilled in the art. The basic principles of the invention defined in the following description may be applied to other embodiments, variations, modifications, equivalents, and other technical solutions without departing from the spirit and scope of the invention.
In the preferred embodiment of the present invention, those skilled in the art will note that the host computer and solid state pressure measuring catheter, etc. to which the present invention relates may be considered prior art.
Preferred embodiments.
The invention discloses an intelligent calibration method for the performance of a solid pressure measuring catheter, which is used for automatic pressure calibration and automatic temperature compensation calibration of the solid pressure measuring catheter and comprises the following steps:
step S1: the control circuit board 500 receives the pressure calibration command transmitted by the upper computer 600, so that the control circuit board 500 respectively controls and adjusts the pressurizing air pump 220 and the electromagnetic valve 230, so that the cavity 410 for placing the solid pressure measuring catheter 700 is stabilized at a constant pressure, and the automatic pressure calibration of the solid pressure measuring catheter 700 is completed;
Step S2: after the automatic calibration of the pressure of the solid state pressure measuring catheter 700 is completed, the upper computer 600 automatically transmits a temperature compensation calibration command to the control circuit board 500, so that the control circuit board 500 controls and adjusts the circulation fan 330 and the surrounding heating conductor 320, respectively, so that the cavity 410 where the solid state pressure measuring catheter 700 is placed is stabilized at a constant temperature, thereby completing the automatic calibration of the temperature compensation of the solid state pressure measuring catheter 700.
Specifically, step S1 includes the steps of:
step S1.1: after receiving the first pressure calibration command transmitted by the upper computer 600, the control circuit board 500 closes the electromagnetic valve, and starts the pressurizing air pump 230 to inflate and pressurize the cavity 410;
step S1.2: the pressure sensor 210 installed at the cavity 410 communicates with the inside of the cavity 410, so that the pressure sensor 210 measures the internal ambient pressure change of the cavity 410 in real time and transmits the pressure signal obtained by detection to the control circuit board 500, (after pressurizing to a certain extent) the control circuit board 500 adjusts the air intake of the pressurizing air pump 220 and the air discharge of the electromagnetic valve 230 according to the first pressure calibration command transmitted by the upper computer 600, so that the internal pressure of the cavity 410 is automatically adjusted to the first calibration pressure (preferably 5kPa ± 0.1 kPa) matched with the first pressure calibration command and the first pressure signal V1 is displayed in real time by the pressure sensor (upper computer), and then the cavity is made to last for a first time (preferably 10 seconds);
Step S1.3: performing pressure zero setting treatment on pressure sensors of all channels of the solid pressure measuring guide pipe after the first time of continuous pressure stabilization (the solid pressure measuring guide pipe is provided with n signal recording channels, each signal recording channel is provided with a built-in diffusion silicon pressure sensor, before calibration, the initial pressure value of the pressure sensor of each channel is different, for example, the initial pressure value of the pressure sensor of the first channel is 1kPa, the initial pressure value of the pressure sensor of the second channel is 1.5kPa, at the moment, the pressure value of a cavity rises by 5kPa, then one upper computer is displayed as 6kPa, one upper computer is displayed as 6.5kPa, so that data is not uniform, thereby subtracting 6kPa from the pressure sensor of the first channel, subtracting 6.5kPa from the pressure sensor of the second channel, and performing zero setting treatment (the pressure sensors of the other channels are also subjected to zero setting treatment) so that 0kPa are displayed on the upper computer, so that data which are easier to read in the subsequent step-up process are acquired, and a circuit board is also arranged for realizing sampling, analog-digital conversion and data transmission of the pressure sensor of each channel and data transmission to the upper computer and calibration parameters of the pressure sensor of each channel, and calibration parameters of the pressure sensor are stored at the same time;
Step S1.4: the control circuit board adjusts the air inlet of the pressurizing air pump and the air outlet of the electromagnetic valve through a second pressure calibration command transmitted by the upper computer, so that the internal pressure of the cavity is automatically adjusted to a second calibration pressure (preferably 50kPa plus or minus 0.1 kPa) matched with the second pressure calibration command, a second pressure signal V2 is displayed in real time through a pressure sensor (the upper computer) arranged in the cavity, and then the cavity is continuously stabilized for a second time (preferably 10 seconds);
step S1.5: the upper computer obtains the pressure output value Pn of each channel through a plurality of pressure sensors of the solid pressure measuring catheter, and calculates the pressure linearity after meeting the condition that the pressure output value Pn of each channel is positioned in a preset pressure range (45 kPa plus or minus 0.1 kPa) through the following formula:
Kn1=Pn/(V2-V1);
kn1 represents the pressure linear coefficient of the first nth channel, pn represents the pressure value of the nth channel (nth pressure channel, n is 1,2, 3.) when the solid state pressure measuring catheter is at the second pressure signal V2;
then, carrying out regression calculation and pressure compensation on the output of the pressure sensors of all the channels through Kn1, so that the output pressure output values of the pressure sensors of all the channels are consistent when the pressure changes are detected, and further, single pressure calibration is completed;
Step S1.6: after the single pressure calibration is successful, the control circuit board controls the electromagnetic valve to deflate and re-executes the step S1.4 and the step S1.5 twice (preferably twice, the specific times can be set according to actual demands), so as to obtain the pressure linear coefficient Kn2 of each channel of the second time and the pressure linear coefficient Kn3 of each channel of the third time, the pressure calibration linear coefficients of each channel of the solid pressure measuring catheter are obtained through average calculation according to the following formula, and are written into a circuit board storage area of the solid pressure measuring catheter (an upper computer is simultaneously connected with the control circuit board and the circuit board of the solid pressure measuring catheter, so that the pressure value of a cavity and the pressure value of each channel are obtained, so that the related pressure linear coefficients are obtained through calculation by the upper computer, and finally, the accurate pressure linear coefficients are written into the circuit board storage area of the solid pressure measuring catheter, so that the pressure values output by the pressure sensors of each channel after compensation are kept consistent when the solid pressure measuring catheter is actually used):
Kave=(Kn1+Kn2+Kn3)/3。
more specifically, step S2 includes the steps of:
step S2.1: the control circuit board receives a first temperature compensation calibration instruction transmitted by the upper computer, then closes the electromagnetic valve and the pressurizing air pump, and starts the circulating fan and the surrounding heating conductor;
Step S2.2: the method comprises the steps that a surrounding heating conductor which surrounds a cavity for heating is divided into a plurality of sections of heating units (including continuous and discontinuous), each section of heating unit can be independently heated, each section of heating unit is provided with a temperature sensor in a matching mode (the number of the heating units is matched with that of the temperature sensors), and each temperature sensor is communicated with the inside of the cavity, so that the temperature sensor measures the internal temperature change of the corresponding cavity (each area) of each section of heating unit in real time, and temperature signals obtained through detection are transmitted to an upper computer through a control circuit board, and are displayed respectively by the upper computer;
step S2.3: monitoring the temperature balance of the cavity through each temperature sensor, and realizing internal temperature adjustment by combining a circulating fan (accelerating temperature balance adjustment) with a surrounding heating conductor, so that the heating temperature of each section of heating unit for each region of the cavity reaches an initial temperature value (30+/-0.5 ℃) matched with a first temperature compensation calibration instruction and is within a preset temperature difference range (preferably 0.1 ℃, if the temperature of which region of the cavity is greater than the temperature of other regions by a preset temperature difference, only the heating temperature of the heating unit corresponding to the region needs to be adjusted), and after the initial temperature value is reached, the control circuit board automatically adjusts the heating temperature of the surrounding heating conductor to realize initial temperature constant, and constant temperature is realized in the cavity for a third time (preferably 2 minutes);
Step S2.4: setting the temperature obtained by the temperature sensor to be T1..Tn, calculating an average value by a formula of Tave 1= (T1+T2..Tn)/n, so as to obtain a temperature value Tave1, wherein the error between Tave1 and the actual set temperature is the constant effective temperature of the current cavity body temperature within a preset value (less than or equal to 0.1 ℃), and carrying out pressure zero setting on the pressure sensors of all channels of the solid side pressure conduit at the moment, otherwise, the cavity continuously carries out constant temperature treatment (the actual current temperature zero setting is more convenient for detection in the subsequent temperature rising process) through a control circuit board;
step S2.5: after the pressure is set to zero, the control circuit board adjusts the circulating fan and the surrounding heating conductor through a second temperature compensation calibration command transmitted by the upper computer, so that the internal temperature of the cavity is automatically adjusted to a second temperature value (preferably 40+/-0.5 ℃ and a calibration point is added in the process of increasing the temperature of the cavity according to a step length of 0.5 or 1 ℃) which is equal to the second temperature value, the heating temperature of the surrounding heating conductor is gradually reduced in the process of continuously increasing the temperature, when the temperature exceeds the second temperature value, the control circuit board starts the pressurizing air pump to suck external low-temperature gas, the electromagnetic valve is started to keep the pressure balance in the cavity, and the second temperature value of the cavity is gradually balanced, and in the process of rising from the initial temperature to the second temperature, rising from the initial temperature by a step length of DeltaT, (wherein DeltaT=0.5 ℃ or 1 ℃) is preferable, when the initial temperature rises by the first step length DeltaT, realizing constant temperature in the cavity for a third time (preferably 2 minutes), re-reading the temperature T1..Tn obtained by the temperature sensor, calculating an average value by a formula Tave 2= (T1+T2..Tn)/n, so as to obtain a temperature value Tave2, wherein the error between Tave2 and the actual set temperature is the constant effective temperature of the current cavity body temperature within a preset value (less than or equal to 0.1 ℃), and simultaneously recording the pressure output values Pnt of all channels of the solid pressure measuring catheter, wherein Pnt represents the pressure value of an nth channel output by the solid pressure measuring catheter when the cavity temperature is T;
Step S2.6: after the temperature calibration of the first step length delta T is finished, heating is continued to the temperature area where the next step length delta T is positioned, so that the temperature is adjusted once when the temperature is measured at each step length, and the difference between the temperature area where the current step length is positioned and the temperature area where the adjacent previous step length is positioned is calculated, so as to obtain the pressure value Pnt output by each channel of the solid pressure measuring catheter after rising by delta T each time m Wherein t is m =T base +DeltaT×m, m is the number of steps, T base Initial calibration room temperature (i.e. Tave1 in step S2.4) up to the second temperature (and obtaining the pressure value Pnt of the last temperature segment) m ) All t will be acquired m Pnt corresponding to temperature section m The pressure values were fitted linearly three times to determine the curve equation:
y n =w 1 t 3 +w 2 t 2 +w 3 t+b;
then w is the coefficient in the formula 1 、w 2 、w 3 And b writing into circuit board storage area y of solid state pressure measuring catheter n The pressure value output by the nth channel pressure sensor when the temperature is at t ℃.
Further, before step S1, the method further includes:
step S0.2: the solid pressure measuring catheter vertically penetrates through the upper cover and is inserted into the cavity, the insertion depth is set to be that the solid pressure measuring catheter contains pressure sensor sections (the pressure sensors of all channels are arranged at different positions, so that the insertion depth of all channels is different), the length of the solid pressure measuring catheter is added with the preset distance (preferably 5 cm) depth position, and the upper cover is screwed down to enable the upper cover to be backlogged with the sealing ring so as to backlog the solid pressure measuring catheter, so that sealing is achieved.
Preferably, step S0.2 is preceded by a step S0.1: after each time the automatic calibration of temperature compensation is completed, the circuit board storage area of the solid state pressure measuring catheter acquires correction time information so as to set a time validity period according to the current correction time information, and judges whether the time validity period is in the next time when the solid state pressure measuring catheter is used, if so, the automatic calibration is not needed (including pressure and temperature calibration), otherwise, the automatic calibration is carried out.
Preferably, in step S0.1, before each calibration of the solid state pressure measurement catheter (i.e. the time period of validity has been exceeded), the upper computer and the control circuit board perform accuracy verification (i.e. determine the current accuracy by several tests of actual temperature and pressure), if the current accuracy is within the effective accuracy, the circuit board memory area automatically updates the time period of validity according to the time of the current accuracy verification and without recalibration, otherwise, automatically recalibrates.
The invention also discloses an intelligent calibration device for the performance of the solid pressure measuring catheter, which comprises a control circuit board, an upper computer, a pressurizing air pump, an electromagnetic valve, a circulating fan and a surrounding heating conductor, wherein:
The control circuit board receives a pressure calibration instruction transmitted by the upper computer, so that the control circuit board respectively controls and adjusts the pressurizing air pump and the electromagnetic valve to enable the cavity for placing the solid pressure measuring catheter to be stable at constant pressure, and the automatic pressure calibration of the solid pressure measuring catheter is completed;
after the automatic calibration of the pressure of the solid pressure measuring catheter is completed, the upper computer automatically transmits a temperature compensation calibration instruction to the control circuit board, so that the control circuit board respectively controls and adjusts the circulating fan and the surrounding heating conductor, and the cavity for placing the solid pressure measuring catheter is stabilized at a constant temperature, thereby completing the automatic calibration of the temperature compensation of the solid pressure measuring catheter.
Pressure calibration and temperature compensation calibration for solid state pressure measurement conduits, comprising (cavity insulating) housing 100, pressure calibration unit 200, temperature compensation calibration unit 300, calibration cavity unit 400 and control circuit board 500, said calibration cavity unit 400 and said control circuit board 500 being both mounted to said housing 100, wherein:
the calibration cavity unit 400 includes a cavity 410, an upper cover 420 and a lower cover 430, a first end (upper edge) of the cavity 410 being connected to the upper cover 420 and a second end (lower edge) of the cavity 410 being connected to the lower cover 430, a solid state pressure measurement catheter 700 being placed in the cavity 410;
The pressure calibration unit 200 includes a pressure sensor 210, a pressurized air pump 220, a solenoid valve 230, and a check valve 240, the pressure sensor 210, the compressor pump 220, and the solenoid valve 230 are electrically connected to the connection end of the control circuit board 500, respectively, the check valve 240 is connected between the pressurized air pump 220 and the solenoid valve 230, and one end of the solenoid valve 230 away from the check valve 240 is connected to the lower cover 430, and the pressure sensor 210 is mounted to the cavity 410 and communicates with the inside of the cavity 410;
the temperature compensation calibration unit 300 includes a temperature sensor 310, a surrounding heating conductor 320 and a circulating fan 330, wherein the temperature sensor 310, the surrounding heating conductor 320 and the circulating fan 330 are respectively and electrically connected with the connection end of the control circuit board 500, the surrounding heating conductor 320 is circumferentially mounted on the outer surface of the cavity 410, the circulating fan 330 is respectively connected with the upper cover 420 and the lower cover 430, and the temperature sensor 310 is mounted in the cavity 410 and is communicated with the interior of the cavity 410.
Specifically, one end of the check valve 240 is connected to the pressurizing air pump 220 through a connection hose 250, and the other end of the check valve 240 is connected to the electromagnetic valve 230 through a connection hose 250 (thereby realizing the conduction of the cavity and the air path formed by the electromagnetic valve and the pressurizing pump);
One end of the circulation fan 330 is connected to the upper cover 420 through a connection hose 250 and the other end of the circulation fan 330 is connected to the lower cover 430 through a connection hose 250 (to realize circulation of gas in the chamber).
More specifically, the surface of the cavity 410 is provided with a pressure sensor mounting hole and a temperature sensor mounting hole, the pressure sensor 210 is mounted to the pressure sensor mounting hole and the temperature sensor 310 is mounted to the temperature sensor mounting hole (so that the inside of the cavity is in sealed communication with the pressure sensor and the temperature sensor, respectively).
Further, a sealing ring 440 (O-ring) is disposed between the first end of the cavity 410 and the upper cover 420.
Further, the input end of the control circuit board 500 is electrically connected to the upper computer 600.
Preferably, a contact sensor is provided between the upper cover 420 and the cavity 410, and the contact sensor is used for monitoring whether the upper cover is screwed down after the solid pressure measuring catheter is inserted into the cavity 410, so as to ensure a sealing state in the calibration process.
Preferably, the invention is also provided with a four-way valve, the high temperature in the cavity 410 is regulated through the four-way valve, when the temperature of the cavity 410 is higher than a set standard value, the control circuit board controls the four-way valve, so that low-temperature air is sucked from the outside to be mixed with high-temperature air in the cavity 410, and meanwhile, the pressure sensor is combined, the vent holes of the four channels are opened to release pressure, so that the pressure balance in the cavity is achieved.
Preferably, the temperature sensor preferably includes a first temperature sensor installed at an upper portion of the cavity, a second temperature sensor installed at a middle portion of the cavity, and a third temperature sensor installed at a lower portion of the cavity.
The 3-path temperature sensor is connected with the upper, middle and lower parts of the cavity and is in sealing connection with the cavity, and the types of the temperature sensor include but are not limited to thermocouple sensors, thermistor sensors, resistance temperature detectors, IC temperature sensors and the like.
The cavity is externally wound with a surrounding heating conductor, the gas in the cavity is heated through direct heat conduction of the cavity, and heating power is controlled by a control circuit board according to the environmental calibration requirement.
The cavity surrounded by the heating body is wrapped in the heat insulation shell, and heat conduction contact between gas in the cavity and the external environment is reduced through the heat insulation shell, so that the effect of heat preservation of the gas in the cavity is achieved.
The pressurized air pump is connected with the cavity through the connecting hose to provide an air source for the cavity, and the other end of the pressurized air pump is connected with the atmosphere to obtain external air.
The one-way valve connected with the pressurizing air pump plays a role in one-way air circulation, and prevents the air in the cavity from circulating to the outside through the pressurizing air pump.
The (air release) electromagnetic valve is connected with the lower cover, the control circuit board controls the air release electromagnetic valve to realize the effect of air release in the cavity, and the control circuit board can control the working state of the air release electromagnetic valve according to the requirement when pressure calibration and temperature calibration are executed.
The circulating fan is connected with the cavity through the connecting flexible connecting pipe, so that gas circulation in the cavity is realized, and the control circuit board for controlling the rotating speed of the fan dynamically adjusts the speed of the fan according to the requirement of a calibration environment, so that the temperature in the cavity is uniform.
The solid pressure measuring catheter adopts a built-in diffusion silicon pressure sensor, the pressure characteristic of the pressure sensor is inversely proportional to the temperature change, and the pressure characteristic is divided into two parts in the calibration process, namely the linear calibration of the pressure of the sensor and the linear calibration of the temperature of the sensor. And pressure linear calibration must be performed before sensor temperature linear calibration is performed during operation. Temperature linearity calibration is also known as temperature linearity compensation.
The principle of the invention is as follows:
the device is used for intelligently calibrating the solid pressure measuring catheter based on the diffusion silicon chips, and the linear error exists among different diffusion silicon chips to influence the actual pressure measurement application, so that the accuracy of output pressure is ensured, and the pressure is linearly calibrated. Meanwhile, the diffusion silicon chip has temperature sensitivity, and pressure output deviation can be influenced under the condition of different temperatures in the same pressure environment, so that pressure loss caused by temperature change needs to be compensated. In view of the above solid state pressure measurement catheter pressure linearity and temperature compensation calibration, the present device calibration includes pressure calibration and temperature compensation calibration. After the solid pressure measuring catheter is calibrated by the device, the calibrated pressure characteristic parameters and temperature compensation parameters are transmitted to the solid pressure measuring catheter through a USB signal by a control circuit board of the device for storage. The device can realize that the accuracy of the pressure output of the pressure performance within the temperature change range of 30-45 ℃ meets the technical design requirement of the solid pressure measuring catheter.
The sealing ring is positioned between the upper edge of the cavity and the upper cover, and when the upper cover is screwed up, the backlog sealing ring deforms to reduce the inner diameter so as to play a role in sealing the solid pressure measuring conduit. The 3-path temperature sensor is positioned at the upper, middle and lower positions of the cavity and communicated with the internal environment of the cavity, measures the temperature change of the internal environment of the cavity, reduces the temperature difference of different positions of the internal environment through mutual comparison of the internal environment temperatures of the three positions, and improves the calibration precision of the solid pressure measuring catheter. The 1-path pressure sensor is positioned at any position of the cavity and communicated with the inside of the cavity, measures the change of the environmental pressure in the cavity and provides a standard pressure value for the calibration of the catheter. The surrounding heating conductor surrounds the outer surface of the cavity and is used for heating the cavity. The circulating fan is respectively connected with the upper edge and the lower edge of the cavity through the connecting hose to provide internal air flow circulation for the cavity, so that the temperature balance in the cavity is achieved. The pressurized air pump is connected with the bottom of the cavity through a connecting hose to provide a pressure air source for the cavity. The control circuit board provides intelligent calibration control driving instructions (from an upper computer) for the device, including pressure detection, temperature detection, heating around a heating conductor, fan operation, air pump operation, electromagnetic valve operation and the like, and provides instruction driving flow for pressure and temperature calibration of the whole device. The connecting hose has a diameter of about 20mm, and a wall thickness of 2-3 mm PU hose or stainless steel corrugated pipe is used for connecting the cavity, the circulating fan and the booster pump, so as to provide a connecting effect for the pressurization and the internal gas circulation of the whole device. The electromagnetic valve is connected with the cavity of the device and the control circuit board through a hose, and when the device executes pressure calibration, the device adjusts proper calibration pressure in the cavity through the deflation of the electromagnetic valve and the air intake of the air pump. The one-way valve is connected with the air pump and the device cavity and provides one-way air flow for the pressurization of the air pump. The cavity heat insulation shell is wrapped in a cavity surrounding the heating conductor, so that heat loss in the heating and constant temperature processes is prevented. The solid pressure measuring catheter is a target for the device to use calibration. The upper computer is connected with the control circuit board through a USB interface or a serial interface to realize data interaction, data acquisition, display and data storage.
The invention can calibrate the pressure performance and the temperature compensation of the solid pressure measuring catheter based on the diffusion silicon chip. The automatic pressure calibration device comprises automatic pressure calibration and automatic temperature compensation calibration, wherein the automatic pressure calibration is characterized in that an upper computer sends functional instruction information to a control circuit board of the device through a USB or serial port interface, and the control circuit board controls the pressurizing work of an air pump, the monitoring of a pressure sensor and the deflation of an electromagnetic valve, so that the stability of a certain constant pressure in a cavity is realized.
For automatic calibration of pressure:
the solid pressure measuring catheter vertically penetrates through the upper cover of the calibration cavity of the device to be inserted into the cavity, the insertion depth is equal to the length of the solid pressure measuring catheter containing the pressure sensor section plus 5cm depth, and the upper cover is enabled to be backlogged with the O-shaped ring to backlog the solid pressure measuring catheter by screwing the upper cover of the calibration cavity, so that sealing is achieved.
The power supply of the device is started, and the detailed implementation steps are as follows:
1) The upper computer sends a pressure calibration instruction to the device, and after the device receives the pressure calibration instruction, the deflation electromagnetic valve is closed, and the pressurizing air pump is started to pressurize the cavity of the device.
2) The pressure sensor monitors the pressure in the cavity in real time, outputs a pressure signal in the cavity to the control circuit board, controls the pressure in the cavity to 5kPa + -0.1 kPa through adjusting and controlling the pressurizing air pump and the (deflating) electromagnetic valve, and displays V1 through the pressure sensor of the device, and continuously stabilizes the pressure for 10 seconds;
3) The upper computer continuously monitors the pressure stabilizing state for 10 seconds, executes the pressure stabilizing state to adjust the initial pressure of the solid pressure measuring catheter, and sets the executing pressure to zero, otherwise, the step 2) is continuously carried out;
4) After the pressure in the step 3 is set to zero, the upper computer sends a command to the control circuit board of the device to require pressurization and voltage stabilization to 50 kPa+/-0.1 kPa, the voltage stabilization is continued for 10 seconds, and the pressure sensor of the device displays V2; otherwise, repeating the step 4.
5) The upper computer continuously monitors the pressure stabilizing state of 50kPa +/-0.1 kPa for 10 seconds, the upper computer acquires the pressure output value Pn of each channel of the solid pressure measuring catheter, P represents the pressure value, n represents a certain pressure channel, firstly, the pressure Pn of each channel is evaluated to meet 45kPa +/-0.1 kPa, and then the pressure linear calculation formula is adopted: kn1=pn/(V2-V1), kn1 represents the first-time individual channel pressure linear coefficient.
6) After the single calibration is successful, the device is executed to open the electromagnetic valve for deflation.
7) Repeating the pressure calibration for three times, obtaining the pressure linearity Kn1, kn2 and Kn3 of each channel, taking the average value, and writing the final calculated linear value kave= (kn1+kn2+kn3)/3 of the pressure sensor of each channel of the solid pressure measuring catheter into a storage area of the solid pressure measuring catheter.
After the pressure calibration is completed, the upper computer automatically executes temperature compensation calibration to the control circuit board of the device, and the detailed implementation steps are as follows:
1) The upper computer sends a temperature compensation calibration instruction to the device, and after the device receives the temperature compensation calibration instruction, the device closes the air release electromagnetic valve and starts the circulating fan and the surrounding heating conductor.
2) Three temperature sensors fixed in the cavity, preferably upper, middle and lower, monitor the temperature change in the cavity in real time; and transmitting the upper, middle and lower temperatures in the cavity to an upper computer for display through a control circuit board.
3) The device is provided with an initial set temperature of 30+/-0.5 ℃, the control circuit board monitors upper, middle and lower temperature areas in the cavity through three temperature sensors, and the temperature in the cavity is fully balanced by adjusting the circulating fan. When the temperature meets the requirement of the initial set temperature, the control circuit board automatically adjusts the heating temperature of the surrounding heating conductor so as to achieve the constant temperature of the initial temperature, and the constant temperature is realized in the cavity for 2 minutes.
4) The upper computer continuously detects the constant temperature state for 2 minutes, displays the temperatures T1, T2 and T3, meets the initial set temperature value, calculates tave1= (T1+T2+T3)/3, executes the initial pressure of the solid pressure measuring catheter, and sets the execution pressure to zero. Otherwise, continuing the steps 2-3.
5) After the pressure setting in the step 4 is completed, the upper computer sends a command to the control circuit board of the device to heat the surrounding conductor to 40 ℃, the control circuit board executes the heating of the surrounding conductor and the operation of the circulating fan, the temperature of the surrounding conductor is gradually reduced along with the continuous rising of the temperature, when the temperature exceeds a set range, the starting air pump is sucked into external low-temperature gas, the deflation electromagnetic valve is opened to keep the pressure balance in the cavity, the cavity temperature balance is gradually realized at 40+/-0.5 ℃, in the process of rising from the initial temperature to the second temperature (40 ℃ +/-0.5 ℃), the temperature is risen from the initial temperature by a step length of DeltaT, (wherein DeltaT=0.5 ℃ or 1 ℃), when the initial temperature rises by the first step length of DeltaT, the first step length of time is realized in the cavity, the temperature T1 obtained by the temperature sensor is read again, the average value Tave2 is calculated through the formula Tave 2= (T1+T 2+. Tn)/n, and the solid state pressure measuring channels with the actual set temperature error being equal to or less than 0.1 ℃ are recorded, and the solid state pressure measuring channels of the temperature is recorded and the solid state pressure measuring channels of the temperature is equal to or less than the temperature of the current temperature of the cavity; .
6) After the temperature calibration of the first step length delta T is finished, heating is continued to the temperature area where the next step length delta T is positioned, so that the temperature is adjusted once when the temperature is measured at each step length, and the difference between the temperature area where the current step length is positioned and the temperature area where the adjacent previous step length is positioned is calculated, so as to obtain the pressure value Pnt output by each channel of the solid pressure measuring catheter after rising by delta T each time m Wherein t is m =T base The number of steps is the number of times T is multiplied by m, T base Initial calibration room temperature (i.e. Tave1 in step S2.4) up to the second temperature (and obtaining the pressure value Pnt of the last temperature segment) m ) All t will be acquired m Phase of temperature sectionPnt of response m The pressure values were fitted linearly three times to determine the curve equation:
Figure BDA0003880352100000201
and (3) obtaining coefficients w1, w2, w3 and b of the formula through temperature calibration of each adjacent step, wherein x is the temperature, and y is the corresponding temperature compensation pressure.
After the pressure and temperature compensation is calibrated, the upper computer is closed, the upper cover of the device is unscrewed, and the solid pressure measuring catheter is taken out for clinical use.
The pressure output of each channel of the solid pressure measuring catheter meets the accuracy requirements (working environment temperature is required to be 30 ℃ -40 ℃ +/-0.1 ℃) of-100 mmHg-100 mmHg+/-1.6 mmHg and 100 mmHg-600 mmHg+/-1.6 percent in use according to the pressure linear calibration and the temperature compensation calibration.
It should be noted that technical features such as an upper computer and a solid pressure measuring catheter related to the present invention application should be regarded as the prior art, and specific structures, working principles, and control modes and spatial arrangement modes possibly related to the technical features should be selected conventionally in the art, and should not be regarded as the invention point of the present invention patent, which is not further specifically expanded and detailed.
Modifications of the embodiments described above, or equivalents of some of the features may be made by those skilled in the art, and any modifications, equivalents, improvements or etc. within the spirit and principles of the present invention are intended to be included within the scope of the present invention.

Claims (6)

1. An intelligent calibration method for the performance of a solid pressure measurement catheter, which is used for automatic pressure calibration and automatic temperature compensation calibration of the solid pressure measurement catheter, is characterized by comprising the following steps:
step S1: the control circuit board receives a pressure calibration instruction transmitted by the upper computer, so that the control circuit board respectively controls and adjusts the pressurizing air pump and the electromagnetic valve to enable the cavity for placing the solid pressure measuring catheter to be stable at constant pressure, and the automatic pressure calibration of the solid pressure measuring catheter is completed;
Step S1 comprises the steps of:
step S1.1: the control circuit board receives a first pressure calibration instruction transmitted by the upper computer, closes the electromagnetic valve, and starts the pressurizing air pump to inflate and pressurize the cavity;
step S1.2: the pressure sensor arranged in the cavity is communicated with the inside of the cavity, so that the pressure sensor measures the internal ambient pressure change of the cavity in real time and transmits pressure signals obtained by detection to the control circuit board, the control circuit board adjusts the air inlet of the pressurizing air pump and the air outlet of the electromagnetic valve according to a first pressure calibration instruction transmitted by the upper computer, so that the internal pressure of the cavity is automatically adjusted to a first calibration pressure matched with the first pressure calibration instruction, the first pressure signal V1 is displayed in real time through the pressure sensor, and then the cavity is continuously stabilized for a first time;
step S1.3: performing pressure zero setting treatment on pressure sensors of all channels of the solid pressure measuring catheter after the first time of continuous pressure stabilization;
step S1.4: the control circuit board adjusts the air inlet of the pressurizing air pump and the air outlet of the electromagnetic valve through a second pressure calibration instruction transmitted by the upper computer, so that the internal pressure of the cavity is automatically adjusted to a second calibration pressure matched with the second pressure calibration instruction, a second pressure signal V2 is displayed in real time through the pressure sensor, and then the cavity is continuously stabilized for a second time;
Step S1.5: the upper computer obtains the pressure output value Pn of each channel through a plurality of pressure sensors of the solid pressure measuring catheter, and calculates the pressure linearity after meeting the condition that the pressure output value Pn of each channel is positioned in a preset pressure range through the following formula:
Kn1=Pn/(V2-V1);
kn1 represents the pressure linear coefficient of the nth channel for the first time, pn represents the pressure value of the nth channel when the solid state pressure measuring catheter is in the second pressure signal V2;
then, carrying out regression calculation and pressure compensation on the output of the pressure sensors of all the channels through Kn1, so that the output pressure output values of the pressure sensors of all the channels are consistent when the pressure changes are detected, and further, single pressure calibration is completed;
step S1.6: after the single pressure calibration is successful, the control circuit board controls the electromagnetic valve to deflate and re-executes the step S1.4 and the step S1.5 for two times, so that the pressure linear coefficient Kn2 of each channel of the second time and the pressure linear coefficient Kn3 of each channel of the third time are obtained, the pressure calibration linear coefficients of each channel of the solid pressure measuring catheter are obtained through average calculation according to the following formula, and the pressure calibration linear coefficients are written into a circuit board storage area of the solid pressure measuring catheter:
Kave=(Kn1+Kn2+Kn3)/3;
step S2: after the automatic calibration of the pressure of the solid pressure measuring catheter is completed, the upper computer automatically transmits a temperature compensation calibration instruction to the control circuit board, so that the control circuit board respectively controls and adjusts the circulating fan and the surrounding heating conductor, and the cavity for placing the solid pressure measuring catheter is stabilized at a constant temperature, thereby completing the automatic calibration of the temperature compensation of the solid pressure measuring catheter.
2. An intelligent calibration method for solid state pressure catheter performance according to claim 1, wherein step S2 comprises the steps of:
step S2.1: the control circuit board receives a first temperature compensation calibration instruction transmitted by the upper computer, then closes the electromagnetic valve and the pressurizing air pump, and starts the circulating fan and the surrounding heating conductor;
step S2.2: the method comprises the steps that a surrounding heating conductor which surrounds a cavity for heating is divided into a plurality of sections of heating units, each section of heating unit can be independently heated, each section of heating unit is provided with a temperature sensor in a matching mode, each temperature sensor is communicated with the inside of the cavity, so that the temperature sensor measures the internal temperature change of the cavity corresponding to each section of heating unit in real time, and temperature signals obtained through detection are transmitted to an upper computer through a control circuit board, so that the upper computer can display the temperature signals respectively;
step S2.3: the temperature balance of the cavity is monitored through each temperature sensor, and the internal temperature adjustment is realized by combining the circulating fan and the surrounding heating conductor, so that the heating temperature of each section of heating unit for each region of the cavity reaches an initial temperature value matched with the first temperature compensation calibration instruction and is within a preset temperature difference range, after the initial temperature value is reached, the control circuit board automatically adjusts the heating temperature of the surrounding heating conductor to realize initial temperature constant temperature, and the constant temperature is realized in the cavity for a third time;
Step S2.4: setting the temperature obtained by the temperature sensor to be T1..Tn, calculating an average value by a formula of Tave 1= (T1+T2..Tn)/n, so as to obtain a temperature value Tave1, wherein the error between Tave1 and the actual set temperature is the constant effective temperature of the current cavity body temperature within a preset value, and carrying out pressure zero setting on the pressure sensors of all channels of the solid side pressure guide pipe at the moment, otherwise, continuously executing constant temperature processing on the cavity body through a control circuit board;
step S2.5: after the pressure is set to zero, the control circuit board adjusts the circulating fan and the surrounding heating conductor through a second temperature compensation calibration command transmitted by the upper computer, so that the internal temperature of the cavity is automatically adjusted to a second temperature value matched with the second temperature compensation calibration command, the heating temperature of the surrounding heating conductor is gradually reduced in the process of continuously rising the temperature, when the temperature exceeds the second temperature value, the control circuit board starts the pressurizing air pump to suck external low-temperature gas, the electromagnetic valve is started to keep the pressure balance in the cavity, the balance of the temperature of the cavity is gradually realized, the second temperature value is gradually realized, and in the process of rising from the initial temperature to the second temperature, the initial temperature is risen by a step length delta T, when the initial temperature rises by the step length delta T, the constant temperature is realized in the cavity for a third time, the temperature T1..Tn obtained by the temperature sensor is read again, the average value is calculated through a formula Tave 2= (T1+T2..Tn)/n, and the solid state pressure measuring channels of the solid state pressure measuring channels are simultaneously output, wherein the solid state pressure measuring channel value is recorded when the solid state pressure measuring channel value of the solid state pressure measuring channel is the solid state pressure measuring channel, and the solid state pressure measuring channel is obtained when the temperature error of the solid state pressure measuring channel is within the preset;
Step S2.6: after the temperature calibration of the first step DeltaT is completed, the heating is continued to the temperature zone where the next step DeltaT is located, therebyThe temperature is regulated once when the temperature is measured in each step length, and then the difference value between the temperature area where the current step length is positioned and the temperature area where the adjacent previous step length is positioned is calculated, so as to obtain the pressure value Pnt output by each channel of the solid pressure measuring catheter after rising by delta T each time m Wherein t is m =T base +DeltaT×m, m is the number of steps, T base Initial calibration at room temperature until rising to the second temperature, all t's acquired m Pnt corresponding to temperature section m The pressure values were fitted linearly three times to determine the curve equation:
y n =w 1 t 3 +w 2 t 2 +w 3 t+b;
then w is the coefficient in the formula 1 、w 2 、w 3 And b is written into a circuit board storage area of the solid pressure measuring catheter, y n The pressure value output by the nth channel pressure sensor when the temperature is at t ℃.
3. An intelligent calibration method for solid state pressure catheter performance according to claim 2, further comprising, prior to step S1:
step S0.2: the solid pressure measuring catheter vertically penetrates through the upper cover and is inserted into the cavity, the insertion depth is set to be the length of the pressure sensor section contained in the solid pressure measuring catheter per se, and the preset distance depth is added, and the upper cover is screwed down, so that the sealing ring is pressed by the upper cover, and the solid pressure measuring catheter is pressed by the upper cover, so that sealing is realized.
4. An intelligent calibration method for solid state pressure catheter performance according to claim 3, further comprising step S0.1 prior to step S0.2: after the automatic calibration of temperature compensation is finished each time, the circuit board storage area of the solid pressure measuring catheter acquires correction time information so as to set a time validity period according to the current correction time information, whether the solid pressure measuring catheter is in the time validity period is judged when the solid pressure measuring catheter is used next time, if yes, the automatic calibration is not needed, and otherwise, the automatic calibration is carried out.
5. An intelligent calibration method for solid state pressure measurement catheter performance according to claim 4, wherein in step S0.1, the upper computer and control circuit board perform accuracy verification on the solid state pressure measurement catheter before each calibration on the solid state pressure measurement catheter, and if the current accuracy is within the effective accuracy, the circuit board memory area automatically updates the time validity period according to the current accuracy verification time and without recalibration, otherwise, recalibration is performed automatically.
6. An intelligent calibration device for solid state pressure measurement catheter performance, characterized in that it is applied to an intelligent calibration method for solid state pressure measurement catheter performance according to any one of claims 1-5, and is characterized by comprising a control circuit board, an upper computer, a pressurized air pump, a solenoid valve, a circulating fan and a surrounding heating conductor, wherein:
The control circuit board receives a pressure calibration instruction transmitted by the upper computer, so that the control circuit board respectively controls and adjusts the pressurizing air pump and the electromagnetic valve to enable the cavity for placing the solid pressure measuring catheter to be stable at constant pressure, and the automatic pressure calibration of the solid pressure measuring catheter is completed;
after the automatic calibration of the pressure of the solid pressure measuring catheter is completed, the upper computer automatically transmits a temperature compensation calibration instruction to the control circuit board, so that the control circuit board respectively controls and adjusts the circulating fan and the surrounding heating conductor, and the cavity for placing the solid pressure measuring catheter is stabilized at a constant temperature, thereby completing the automatic calibration of the temperature compensation of the solid pressure measuring catheter.
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Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116412862B (en) * 2023-06-02 2023-08-04 陇东学院 Natural gas flow measuring device based on automatic calibration

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN207600652U (en) * 2017-12-27 2018-07-10 上汽大众汽车有限公司 Automobile rear case compresses force checking device
CN115046944A (en) * 2018-07-11 2022-09-13 唯亚威通讯技术有限公司 Focus linear model correction and linear model correction for multivariate calibration model maintenance

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4399515A (en) * 1981-03-31 1983-08-16 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Self-correcting electronically scanned pressure sensor
EP0177491B2 (en) * 1984-03-30 1994-04-27 Rosemount Inc. Pressure compensated differential pressure sensor and method
US5361218A (en) * 1992-08-11 1994-11-01 Itt Corporation Self-calibrating sensor
US20050187430A1 (en) * 2004-02-19 2005-08-25 Medtronic, Inc. Fluid charging mechanism for balloon catheter system
US20060018528A1 (en) * 2004-04-27 2006-01-26 Northwestern University Imaging, diagnostic, and therapeutic devices and methods of use thereof
EP2725335B1 (en) * 2012-10-23 2015-09-02 Sartorius Stedim Biotech GmbH Method and device for verification and/or calibration of a pressure sensor
US10143416B2 (en) * 2013-08-01 2018-12-04 The Regents Of The University Of California Quantitation and display of impedance data for estimating gastroenterology tract parameters
US10349850B2 (en) * 2015-05-20 2019-07-16 Thd S.P.A. Manometric probe
CN106404222B (en) * 2016-09-26 2019-03-08 西北工业大学 The deep section detection system of ocean temperature based on combined type high precision measuring temperature cable
US11813070B2 (en) * 2017-08-10 2023-11-14 Vipun Medical Nv Apparatus for measuring pressure changes in stomach
CN110200645A (en) * 2019-06-27 2019-09-06 上海市计量测试技术研究院 Detect the device and method of solid-state esophageal manometry system
CN112484916B (en) * 2020-11-27 2022-04-19 北京航天计量测试技术研究所 Temperature response characteristic calibration method for patch type pressure sensor
CN113375858A (en) * 2021-06-24 2021-09-10 北京康斯特仪表科技股份有限公司 Pressure controller and pressure calibration method based on same

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN207600652U (en) * 2017-12-27 2018-07-10 上汽大众汽车有限公司 Automobile rear case compresses force checking device
CN115046944A (en) * 2018-07-11 2022-09-13 唯亚威通讯技术有限公司 Focus linear model correction and linear model correction for multivariate calibration model maintenance

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