CN115569269A - Injection needle for transcranial bone marrow and using method thereof - Google Patents
Injection needle for transcranial bone marrow and using method thereof Download PDFInfo
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- CN115569269A CN115569269A CN202110762361.XA CN202110762361A CN115569269A CN 115569269 A CN115569269 A CN 115569269A CN 202110762361 A CN202110762361 A CN 202110762361A CN 115569269 A CN115569269 A CN 115569269A
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- Prior art keywords
- needle
- skull
- bone marrow
- transcranial
- core
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/46—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for controlling depth of insertion
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
Abstract
The invention relates to the technical field of medical instruments, and provides a transcranial bone marrow injection needle. The method comprises the following steps: the skull bone marrow needle is provided with a needle core, the lower end of the needle core is provided with a needle point, the upper end of the needle core is provided with a rotating handle, and the outside of the needle core is provided with threads; the outside of nook closing member is provided with the sleeve pipe, sheathed tube lower extreme is provided with and blocks, sheathed tube outer wall is provided with a plurality of side openings. The invention has the beneficial effects that: the blocking device can prevent the needle core from puncturing too deeply to directly puncture the skull to damage the dura mater, and the distance between the blocking device and the needle point can be adjusted in the middle of 2-10mm to adapt to the skull thickness of different types of people; in addition, the liquid medicine can flow in through the through holes at the lower end of the sleeve and also can flow in through the side holes on the outer wall of the plurality of sleeves, so that the liquid medicine can be efficiently and uniformly input, and the treatment effect is improved.
Description
Technical Field
The invention relates to the technical field of medical instruments, in particular to a transcranial bone marrow injection needle and a using method thereof.
Background
The blood-brain barrier is an important physiological barrier protecting the central nervous system from the effects of systemic factors in the periphery, and is also the biggest obstacle to drug delivery in nervous system diseases. In recent years, the discovery of the brain lymphoid system and the meningeal lymphatic vessels and the research on the immune monitoring function of the meninges and the skull bone marrow on the brain suggest that the brain can directly perform cell and molecule exchange with the skull bone marrow through a vascular system, the exchange crosses the blood brain barrier, and the suggestion that the drug delivery can be performed through the skull bone marrow, the drug delivery can directly and quickly reach the brain parenchyma through the blood brain barrier, and the drug administration efficiency is improved.
We confirmed in animal experiments that injection of fluorescent contrast agents into the skull bone marrow of mice/rats, the contrast agents can successfully penetrate into cerebrospinal fluid and brain parenchyma, suggesting that central nervous system diseases, including acute brain injury such as cerebral ischemia, cerebral hemorrhage, brain trauma, can be treated by administration of skull bone marrow; neurodegenerative diseases such as Alzheimer's disease, parkinson's disease, motor neuron disease, etc.; neurological diseases such as multiple sclerosis, neuromyelitis optica lineage diseases, autoimmune encephalitis, etc.; and epilepsy.
The existing intramedullary nail is inconvenient to use, is easy to penetrate too deeply, causes unnecessary injury to patients, and has poor liquid medicine input effect and low efficiency.
Disclosure of Invention
The invention aims to provide a transcranial bone marrow injection needle and a using method thereof, which aim to solve the problems in the prior art.
In order to realize the purpose, the invention adopts the technical scheme that: a transcranial bone marrow injection needle comprising: the skull bone needle is characterized in that a needle core is arranged in the skull bone needle, the lower end of the needle core is provided with a needle point, the upper end of the needle core is provided with a rotating handle, and the outside of the needle core is provided with threads; the outside of nook closing member is provided with the sleeve pipe, sheathed tube lower extreme is provided with and blocks, sheathed tube outer wall is provided with a plurality of side openings.
In an alternative embodiment, the whole of the barrier is in a conical structure, and the distance between the barrier and the needle tip can be adjusted between 2mm and 10 mm.
In an optional embodiment, the number of the side holes is 6, and the 6 side holes are symmetrically arranged on the outer wall of the sleeve.
In an optional embodiment, the upper end of the cannula can be sleeved with a medicine infusion device.
In an optional embodiment, the upper end of the cannula is provided with an annular bulge, and the cannula is connected with the medicine infusion apparatus through the annular bulge.
In an optional embodiment, the drug infusion device is an injector or a drug storage bag.
In another aspect, the present invention provides a method for using the injection needle for transcranial bone marrow as described above, comprising the steps of:
and 3, connecting an injector and injecting 0.5-2 ml of physiological saline to verify whether the needle head is in the skull barrier, and connecting a medicine infusion apparatus to infuse the patient after confirming that the physiological saline is injected without resistance.
In an optional embodiment, in the step 1, the skull bone marrow needle insertion process is: the rotating handle is rotated to drive the needle core, and the needle core is screwed into the skull through the needle point and the threads.
In an alternative embodiment, in step 1, the needle core is limited from excessively penetrating into the skull by the blocking.
The invention has the beneficial effects that:
(1) The outer part of the needle core in the injection needle of the transcranial bone marrow is provided with the sleeve, the lower end of the sleeve is provided with the barrier, the needle core can be prevented from puncturing too deeply to directly puncture the skull to damage the dura mater, and the distance between the barrier and the needle point can be adjusted in the middle of 2-10mm to adapt to the thickness of the skull of different types of people; in addition, the outer wall of the sleeve is provided with a plurality of side holes, and the liquid medicine can flow in through the through holes at the lower end of the sleeve and also can flow in through the side holes, so that the liquid medicine can be efficiently and uniformly input, and the treatment effect is improved.
(2) The upper end of the needle core in the injection needle for transcranial bone marrow is provided with the rotating handle, the outside of the needle core is provided with the thread, the rotating handle drives the needle core with the thread to be rapidly screwed into the skull, and meanwhile, the cannula can be kept in the skull, so that the operation is simple and rapid.
(3) The sleeve in the injection needle of the transcranial bone marrow can be connected with various medicine infusion devices, the practicability is strong, and the syringe injection or other infusion devices can be selected according to the medicine capacity for infusion, such as a syringe or a medicine storage bag.
Drawings
In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the drawings used in the embodiments or the prior art descriptions will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and it is obvious for those skilled in the art that other drawings can be obtained according to the drawings without creative efforts.
Fig. 1 is a schematic view illustrating an overall structure of a transcranial bone marrow injection needle according to an embodiment of the present invention.
Fig. 2 is a left side view of a transcranial bone marrow injection needle according to an embodiment of the present invention.
FIG. 3 isbase:Sub>A sectional view taken along line A-A of FIG. 2 according to the present invention.
Fig. 4 is a schematic view illustrating the overall structure of a transcranial bone marrow injection needle according to another embodiment of the present invention.
Fig. 5 is a left side view of a transcranial bone marrow injection needle according to another embodiment of the present invention.
FIG. 6 is a cross-sectional view taken along line B-B of FIG. 5 in accordance with the present invention.
Wherein, the reference numbers in the figures are: 1. the handle is rotated, the needle core is 2, the needle point is 21, the needle point is 22, the thread is 3, the sleeve is 31, the annular bulge is 32, the side hole is 33, the blocking part is 4, and the medicine storage bag is arranged.
Detailed Description
In order to make the technical problems, technical solutions and advantageous effects of the present invention more clearly understood, the present invention is further described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.
It will be understood that when an element is referred to as being "secured to" or "disposed on" another element, it can be directly or indirectly disposed on the other element. When an element is referred to as being "connected to" another element, it can be directly or indirectly connected to the other element. The terms "upper", "lower", "left", "right", "front", "back", "vertical", "horizontal", "top", "bottom", "inner", "outer", etc. indicate orientations or positions based on the orientations or positions shown in the drawings, and are for convenience of description only and not to be construed as limiting the technical solution. The terms "first", "second" and "first" are used merely for descriptive purposes and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features. The meaning of "plurality" is two or more unless specifically limited otherwise.
Referring to fig. 1-6, the present embodiment provides a transcranial bone marrow injection needle, which includes: the skull bone marrow needle is characterized in that a needle core 2 is arranged in the skull bone marrow needle, the needle core 2 is provided with a needle point 21 at the lower end of the needle core 2, a rotating handle 1 is arranged at the upper end of the needle core 2, and threads 22 are arranged outside the needle core 2; the handle 1 is rotated to drive the needle core 2 to rotate, the needle core 2 can be quickly screwed into the skull through the thread 22 and the needle point 21, and the operation is simple and quick.
Specifically, the sleeve 3 is arranged outside the needle core 2, the barrier 33 is arranged at the lower end of the sleeve 3, the whole barrier 33 is of a conical structure, the distance between the barrier 33 and the needle point 21 can be adjusted between 2mm and 10mm, and the barrier 33 can prevent the needle core from penetrating too deep to directly puncture the skull to damage the dura mater so as to adapt to the thickness of the skull of different types of people. It should be noted that the outer wall of the casing 3 is provided with a plurality of side holes 32, preferably, the number of the plurality of side holes 32 is 6, and 6 side holes 32 are symmetrically arranged on the outer wall of the casing 3. The liquid medicine can flow in through the through hole at the lower end of the sleeve 3 and also can flow in through the plurality of side holes 32, so that the liquid medicine can be input efficiently and uniformly, and the treatment effect is improved.
Further, the upper end of the cannula 3 can be sleeved with a medicine infusion apparatus. The upper end of the sleeve 3 is provided with the annular bulge 31, the sleeve 3 is connected with a medicine infusion apparatus through the annular bulge 31, the connection is reliable, the practicability is high, and an injector can be used for injection or other infusion apparatuses can be selected for infusion according to the volume of the medicine, such as the injector or the medicine storage bag 4.
Example one
Referring to fig. 1-3, step 1, local anesthesia is performed on the head of a patient through lidocaine in an anesthesia needle, the skull intramedullary nail is inserted into a skull along a puncture trace of the anesthesia needle, and a sleeve 3 is inserted into the skull intramedullary nail along with the skull intramedullary nail; the skull bone marrow needle puncture process is as follows: the handle 1 is rotated to drive the needle core 2, the needle core 2 is screwed into the skull through the needle point 23 and the thread 22, the barrier 33 limits the needle core 21 to penetrate the skull in a transition way, and the needle core is prevented from penetrating too deep to directly penetrate the skull to damage the dura mater so as to adapt to the thickness of the skull of different types of people. Step 2, after the skull bone marrow needle is punctured into the skull barrier, the skull bone marrow needle is fixed in the skull, the needle core 21 is pulled out, and the cannula 3 is left in the skull; step 3, connecting an injector and injecting 0.5ml-2ml of normal saline to verify whether the needle is in the skull plate barrier, and after confirming that the normal saline is injected without resistance, connecting the injector with a medicine through the annular bulge 31 to infuse a patient, wherein the steps are as follows: the medical solution flows into the patient through the through hole at the lower end of the cannula 3 and the plurality of side holes 32 of the outer wall.
Example two
Referring to fig. 4-6, step 1, local anesthesia is performed on the head of a patient through lidocaine in the anesthesia needle, the skull intramedullary nail is inserted into the skull along a puncture trace of the anesthesia needle, and a sleeve 3 is inserted into the skull intramedullary nail along with the skull intramedullary nail; the skull bone marrow needle puncture process is as follows: the handle 1 is rotated to drive the needle core 2, the needle core 2 is screwed into a skull through the needle point 23 and the thread 22, the barrier 33 limits the needle core 21 to penetrate the skull in a transition way, and the needle core is prevented from penetrating too deep to directly penetrate the skull to damage a dura mater so as to adapt to the thickness of the skull of different types of people. Step 2, after the skull bone marrow needle is punctured into the skull barrier, the skull bone marrow needle is fixed in the skull, the needle core 21 is pulled out, and the cannula 3 is left in the skull; step 3, connecting an injector and injecting 0.5ml-2ml of physiological saline to verify whether the needle head is in the skull barrier, and after confirming that the physiological saline is injected without resistance, connecting an air bag filled with liquid medicine through the annular bulge 31 to carry out infusion on a patient, wherein the steps are as follows: the medical liquid flows into the patient through the through hole at the lower end of the cannula 3 and the plurality of side holes 32 of the outer wall.
The above description is intended to be illustrative of the preferred embodiment of the present invention and should not be taken as limiting the invention, but rather, the intention is to cover all modifications, equivalents, and alternatives falling within the spirit and scope of the invention.
Claims (9)
1. A transcranial bone marrow injection needle comprising: the skull bone needle is characterized in that a needle core (2) is arranged in the skull bone needle, a needle point (21) is arranged at the lower end of the needle core (2), a rotating handle (1) is arranged at the upper end of the needle core (2), and threads (22) are arranged outside the needle core (2);
the method is characterized in that: the outside of nook closing member (2) is provided with sleeve pipe (3), the lower extreme of sleeve pipe (3) is provided with and blocks (33), the outer wall of sleeve pipe (3) is provided with a plurality of side openings (32).
2. A transcranial bone marrow injection needle according to claim 1, characterized in that the whole of the block (33) is of a conical structure, and the distance between the block (33) and the needle tip (21) is adjustable between 2mm and 10 mm.
3. A transcranial bone marrow injection needle according to claim 2, characterized in that the number of the side holes (32) is 6, and 6 side holes (32) are symmetrically arranged on the outer wall of the casing (3).
4. A transcranial bone marrow injection needle according to claim 1, characterized in that a drug infusion set is sleeved on the upper end of the casing (3).
5. A transcranial bone marrow injection needle according to claim 4, characterized in that an annular protrusion (31) is arranged at the upper end of the cannula (3), and the cannula (3) is connected with the drug infusion set through the annular protrusion (31).
6. A transcranial bone marrow injection needle according to claim 5, characterized in that the drug infusion set is a syringe or a drug reservoir (4).
7. Use of a transcranial bone marrow injection needle according to any one of claims 1-6, comprising the steps of:
step 1, local anesthesia is carried out on the head of a patient through lidocaine in an anesthetic needle, a skull bone marrow needle is punctured into a skull along a puncture trace of the anesthetic needle, and a sleeve (3) is punctured along with the skull bone marrow needle;
step 2, after the skull bone marrow needle is punctured into the skull barrier, the skull bone marrow needle is fixed in the skull, the needle core (21) is pulled out, and the cannula (3) is left in the skull;
and 3, connecting an injector and injecting 0.5-2 ml of physiological saline to verify whether the needle head is in the skull barrier, and connecting a medicine infusion apparatus to infuse the patient after confirming that the physiological saline is injected without resistance.
8. The use method according to claim 7, wherein in the step 1, the skull bone marrow needle puncture process is as follows: the rotating handle (1) is rotated to drive the needle core (2), and the needle core (2) is screwed into the skull through the needle point (23) and the thread (22).
9. Use according to claim 7, wherein in step 1 the excessive penetration of the core needle (21) into the skull is limited by the stop (33).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110762361.XA CN115569269A (en) | 2021-07-06 | 2021-07-06 | Injection needle for transcranial bone marrow and using method thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110762361.XA CN115569269A (en) | 2021-07-06 | 2021-07-06 | Injection needle for transcranial bone marrow and using method thereof |
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| CN115569269A true CN115569269A (en) | 2023-01-06 |
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| CN202110762361.XA Pending CN115569269A (en) | 2021-07-06 | 2021-07-06 | Injection needle for transcranial bone marrow and using method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115919432A (en) * | 2023-03-15 | 2023-04-07 | 吉林大学第一医院 | Be used for preventing fat particle input device in marrow reinfusion liquid |
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2021
- 2021-07-06 CN CN202110762361.XA patent/CN115569269A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115919432A (en) * | 2023-03-15 | 2023-04-07 | 吉林大学第一医院 | Be used for preventing fat particle input device in marrow reinfusion liquid |
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