CN115568908A

CN115568908A - Thrombectomy support capable of preventing thrombi from escaping

Info

Publication number: CN115568908A
Application number: CN202211202965.XA
Authority: CN
Inventors: 李峥; 钟旭飘; 周凯旋; 赵中
Original assignee: Zhiyu Medical Technology Guangzhou Co ltd
Current assignee: Zhiyu Medical Technology Guangzhou Co ltd
Priority date: 2022-09-29
Filing date: 2022-09-29
Publication date: 2023-01-06

Abstract

The invention discloses a thrombus taking support capable of preventing thrombus from escaping, which belongs to the technical field of medical instruments. The arc-shaped clamping bolt structure on the inner side of the product is more beneficial to fixing the embolism, prevents the embolism from escaping from the hollow part and the far end, greatly reduces the risk of dropping the thrombus, avoids causing secondary embolism of a patient and reduces the death risk of the patient; the arc-shaped clamping bolt structure has a folding function, does not influence the overall outer diameter of the bolt taking bracket, and can be normally folded and reduced in diameter; and the contractible internal structure and the anti-disengagement structure can also reduce the damage to the vessel wall.

Description

Thrombectomy support capable of preventing thrombi from escaping

Technical Field

The invention relates to the technical field of medical instruments, in particular to a thrombus taking support capable of preventing thrombus from escaping.

Background

According to statistical data, the number of people suffering from stroke in China is 1318 ten thousand; wherein, the number of patients suffering from hemorrhagic stroke is 264 ten thousand, and the number of patients suffering from ischemic stroke is 1054 ten thousand. According to the new disease percentage, the ischemic and hemorrhagic percentages of 2017 stroke patients are 71.6% and 28.4%, respectively. The prevalence ratio of ischemic stroke is higher than that of hemorrhagic stroke, and the prevalence ratio is in an ascending stage.

According to the Chinese stroke prevention report in 2018, the incidence rate of the Chinese acute stroke in 2017-2018 is 80% -90%, which is much higher than the incidence rate of the chronic ischemic stroke. According to the data of Frost Shalivin, the number of the Chinese acute ischemic cerebral apoplexy is increased from 260 ten thousand in 2014 to 330 thousand in 2018, and the CAGR in 4 is 6.14%.

Thus, the clinical importance of stroke treatment is seen. At present, the clinical treatment means aiming at the acute stroke comprises a plasmin treatment means and a mechanical thrombus removal treatment means, and the clinical effect of the mechanical thrombus removal treatment means is accepted by a plurality of patients and clinics.

The clinical representation of mechanical thrombus removal is a thrombus removal support which is the main means of the existing clinical treatment. Most of the existing embolectomy stents are cut by nickel-titanium metal tubes or profiles, or are combined with a welding process after being cut, so that the required embolectomy design structure is processed.

The most adoption distal end open type design of prior art scheme, the purpose plays the middle section support and receives the thrombus when oppressing, and the distal end can keep the tension to the vascular wall. But can imbed the inside thrombus of support, probably drag along with getting the bolt, along with the continuous enlargeing of withdrawal in-process blood vessel diameter, the support compression diameter kick-backs, and the support shrink power is not enough, and the thrombus of normal position in support inside often has the risk that drops to distal end opening position.

If consider to increase binding off structure at the distal end, need increase welding processes, too complicated, the structure of distal end binding off simultaneously, prior art scheme is mostly toper connection structure, and distal portion diameter also can shrink along with the structure shrink of card bolt position support when can causing the support card bolt, causes the risk that the thrombus escaped from the support wall outside and drops.

Disclosure of Invention

The invention aims to provide a thrombus taking support capable of preventing thrombus from escaping so as to solve the technical problem that thrombus is easy to separate when the thrombus support in the prior art is dragged for taking thrombus.

The invention provides a thrombus taking support capable of preventing thrombus from escaping, which comprises a hollow tubular support main body, wherein the axis is the axis of the support, the inner cavity of the support main body is used for capturing thrombus in a blood vessel, the support main body is formed by laser cutting a shape memory alloy tube, A-type meshes and B-type meshes are cut on the surface array of the shape memory alloy tube, a first arc branch is arranged in the A-type meshes, after the shape memory alloy tube is shaped into the tubular support main body, the first arc branch is bent towards the inner side of the axis of the support and shaped into a bent first arc branch, and the thrombus is clamped between the inner wall of the support main body and the bent first arc branch.

Further, after the stent main body is shaped, the width W 'of the bent first arc-shaped branch is larger than the width D' of the A-shaped mesh. When the arc-shaped branches shrink to fix thrombus, the thrombus is not easy to escape from the inner wall of the stent main body to the outer wall of the stent main body.

Furthermore, a second arc branch and a third arc branch are arranged in the B-shaped mesh, after the shape memory alloy tube is shaped into a tubular stent main body, the second arc branch and the third arc branch are bent towards the inner side of the axis of the stent and shaped into a bent second arc branch and a bent third arc branch, and the thrombus is clamped between the inner wall of the stent main body and the bent second arc branch and the bent third arc branch. In the structure, the arc-shaped bidirectional clamping bolt structure formed by the bent second arc-shaped branch and the bent third arc-shaped branch on the inner side of the structure is more favorable for fixing the plug and preventing the plug from escaping from the hollow part and the far end, the whole support keeps a normal folding function, the whole outer diameter of the plug taking support is not influenced, and the diameter of the plug taking support can be normally folded and reduced.

Furthermore, in the shaped stent main body, the bent third arc-shaped branch of the B-shaped mesh is positioned on the side close to the axis of the bent second arc-shaped branch. When the stent main body is recycled and compressed, the bent third arc-shaped branch is not easy to be separated from the inner wall to the outer wall of the Z-shaped stent, so that the blood vessel is damaged.

Further, the support main body is subjected to high-temperature heat treatment by adopting a heat setting die to form a barreled support structure, the first arc branch of the A-shaped mesh or the second arc branch and the third arc branch of the B-shaped mesh are sequentially subjected to shaft center inner side setting by using a tool, and secondary heat treatment is performed to form the structure of the support main body.

Further, the stent main body can be directly cut by the shape memory alloy sheet and curled and shaped into a straight hollow structure.

Compared with the prior art, the invention has the beneficial effects that:

firstly, in the prior art scheme, most of thrombus taking stents adopt a far-end opening type design, the aim is that when a middle section stent is compressed by thrombus, the far end can keep the tension on the vascular wall, but the thrombus can be embedded into the stent, the thrombus can be dragged along with the thrombus taking, the compressed diameter of the stent rebounds along with the continuous amplification of the diameter of the blood vessel in the retraction process, the stent has insufficient shrinkage force, and the thrombus in situ in the stent often has the risk of falling off to a far-end opening part; meanwhile, the arc-shaped clamping bolt structure on the inner side is more beneficial to fixing the embolism, prevents the embolism from escaping from the hollow part and the far end, greatly reduces the risk of dropping the thrombus, avoids causing secondary embolism of a patient and reduces the death risk of the patient; the arc-shaped bolt clamping structure has a folding function, does not influence the overall outer diameter of the bolt taking bracket, and can be normally folded and reduced in diameter; and the contractible internal structure and the anti-disengagement structure can also reduce the damage to the vessel wall.

In the structure, the bent second arc-shaped branch and the bent third arc-shaped branch on the inner side of the B-shaped mesh form an arc-shaped bidirectional clamping bolt structure, so that the plug can be fixed more conveniently, the plug can be prevented from escaping from the hollow part and the far end, the whole support can be normally folded, the whole outer diameter of the plug taking support is not influenced, and the plug taking support can be normally folded and contracted.

Drawings

In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the embodiments or the prior art descriptions will be briefly described below, and it is obvious that the drawings in the following description are some embodiments of the present invention, and other drawings can be obtained by those skilled in the art without creative efforts.

FIG. 1 is a schematic view of a second embodiment of a thrombectomy support apparatus according to the present invention;

FIG. 2 is a schematic view of a second embodiment of the embolic stent deployed according to the present invention;

FIG. 3 is a schematic view of a third embodiment of the present invention showing the deployed thrombectomy stent;

FIG. 4 is a three-view illustration of a second embodiment of the present invention of a embolic support machining blank;

FIG. 5 is a third perspective view of a second embodiment of the present invention;

FIG. 6 is a third view of the second embodiment of the present invention showing the operation of the thrombectomy stent;

FIG. 7 is a block diagram of the working principle of the thrombectomy stent in the second embodiment of the present invention;

FIG. 8 is a three-dimensional view of a first embodiment of the invention;

FIG. 9 is a schematic view of the first embodiment of the present invention showing the embolic stent deployed;

FIG. 10 is a schematic view of a first embodiment of the invention showing the construction of a thrombectomy stent;

FIG. 11 is a cross-sectional view of a first embodiment of the present invention, showing a key holder;

FIG. 12 is a three-dimensional view of the working principle of the thrombectomy carriage according to the first embodiment of the present invention;

fig. 13 is a block diagram illustrating the operation of the thrombectomy stent in the first embodiment of the present invention.

Reference numerals:

1. a proximal side; 2. a distal side; 3. the axis of the bracket; 4. thrombosis; 5. type A mesh; 51. a first arcuate branch; 6. b type mesh; 61. a second arcuate branch; 62. a third arcuate branch; 7. bending the first arc branch; 8. bending the second arc branch; 9. and a third arc branch after bending.

Detailed Description

The technical solutions of the present invention will be described clearly and completely with reference to the accompanying drawings, and it should be understood that the described embodiments are some, but not all embodiments of the present invention.

The components of embodiments of the present invention generally described and illustrated in the figures herein may be arranged and designed in a wide variety of different configurations. Thus, the following detailed description of the embodiments of the present invention, presented in the figures, is not intended to limit the scope of the invention, as claimed, but is merely representative of selected embodiments of the invention.

All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc. indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of description and simplification of description, but do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and thus, should not be construed as limiting the present invention. Furthermore, the terms "first," "second," and "third" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.

In the description of the present invention, it should be noted that, unless otherwise explicitly specified or limited, the terms "mounted," "connected," and "connected" are to be construed broadly, e.g., as meaning either a fixed connection, a removable connection, or an integral connection; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meanings of the above terms in the present invention can be understood in specific cases to those skilled in the art.

Example 1:

referring to fig. 8 to 13, the thrombus extraction stent capable of preventing thrombus from escaping according to an embodiment of the present invention includes a hollow tubular stent main body, wherein the axis is a stent axis 3, an inner cavity of the stent main body is used for capturing thrombus 4 in a blood vessel, the stent main body is formed by laser cutting a shape memory alloy tube, a type a mesh 5 and a type B mesh 6 are cut on the surface of the shape memory alloy tube in an array manner, a first arc branch 51 is arranged in the type a mesh 5, after the shape memory alloy tube is shaped into the tubular stent main body, the first arc branch 51 is bent and shaped towards the inner side of the stent axis 3 to form a bent first arc branch 7, and the thrombus 4 is clamped between the inner wall of the stent main body and the bent first arc branch 7. In the prior art, most of thrombus taking stents adopt a far-end opening type design, the aim is that when a middle-section stent is compressed by thrombus 4, the far end can keep the tension on the vascular wall, but the thrombus 4 in the stent can be embedded, and is possibly dragged along with the thrombus taking, the compressed diameter of the stent rebounds along with the continuous amplification of the diameter of the blood vessel in the withdrawing process, the shrinkage force of the stent is insufficient, and the thrombus 4 in situ in the stent often has the risk of falling off towards the far-end opening part; meanwhile, the arc-shaped clamping bolt structure on the inner side is more beneficial to fixing the embolism, prevents the embolism from escaping from the hollow part and the far end, greatly reduces the risk of dropping the thrombus 4, avoids causing secondary embolism of a patient and reduces the death risk of the patient; the arc-shaped bolt clamping structure has a folding function, does not influence the overall outer diameter of the bolt taking bracket, and can be normally folded and reduced in diameter; and the contractible internal structure and the anti-disengagement structure can also reduce the damage to the vessel wall.

Specifically, after the stent main body is shaped, the width W 'of the bent first arc-shaped branch 7 is more than the width D' of the A-shaped mesh 5. When the arc-shaped branches shrink to fix the thrombus 4, the thrombus 4 is not easy to escape from the inner wall of the stent main body to the outer wall of the stent main body.

The length H of the half B-shaped mesh 6 of the stent main body is 8.8mm, the width W of the bent first arc-shaped branch 7 after shaping is 13.3mm, the mesh width D of the stent main body after unfolding is 12.1mm, the width of the stent main body beam is 0.08mm, the overall length of the embolectomy stent is 61mm, the thickness of the shape memory alloy tube or the shape memory alloy sheet is about 0.1mm, and the shape memory alloy is mostly made of nickel-titanium alloy.

Example 2:

as shown in fig. 1-2 and 4-7, another arrangement manner of the arc-shaped branches in the B-shaped mesh 6 is provided in the embodiment, wherein a second arc-shaped branch 61 and a third arc-shaped branch 62 are provided in the B-shaped mesh 6, after the shape memory alloy tube is shaped into the tubular stent main body, both the second arc-shaped branch 61 and the third arc-shaped branch 62 are bent towards the inner side of the stent axle center 3 and shaped into a bent second arc-shaped branch 8 and a bent third arc-shaped branch 9, and the thrombus 4 is clamped between the stent main body inner wall and the bent second arc-shaped branch 8 and the bent third arc-shaped branch 9. In the structure, the arc-shaped bidirectional clamping bolt structure formed by the bent second arc-shaped branch 8 and the bent third arc-shaped branch 9 on the inner side of the structure is more favorable for fixing the plug and preventing the plug from escaping from the hollow part and the far end, the whole support keeps a normal folding function, the whole outer diameter of the plug taking support is not influenced, and the plug taking support can be folded and contracted normally.

Specifically, in the shaped stent main body, the bent third arc-shaped branch 9 of the B-shaped mesh 6 is positioned on the paraxial side of the bent second arc-shaped branch 8. When the stent main body is recycled and compressed, the third arc-shaped branch 9 is not easy to be separated from the inner wall to the outer wall of the Z-shaped stent after being bent, so that the blood vessel is damaged.

Specifically, the bracket main body is subjected to high-temperature heat treatment by adopting a heat setting die to be set into a barreled bracket structure, then the first arc-shaped branch 51 of the A-shaped mesh 5 or the second arc-shaped branch 61 and the third arc-shaped branch 62 of the B-shaped mesh 6 are sequentially subjected to axial center inner side setting by using a tool, and secondary heat treatment is performed to form the structure of the bracket main body.

Specifically, the stent main body can be directly cut from the shape memory alloy sheet and curled and shaped into a straight-tube hollow structure.

Wherein the arc length of the second arc-shaped branch 61 is 8.8mm, the arc length of the third arc-shaped branch 62 is 11.98mm, the length from the end point 1 at the proximal side to the end point 2 at the distal side of the B-shaped mesh 6 is 12.6mm, the thickness of the shape memory alloy tube or the shape memory alloy sheet is about 0.1mm, and the shape memory alloy is nickel titanium alloy mostly.

Example 3:

based on example 2, as shown in fig. 3, the shape memory alloy sheet of parallelogram in this example can be formed by laser cutting.

Finally, it should be noted that: the above embodiments are only used to illustrate the technical solution of the present invention, and not to limit the same; while the invention has been described in detail and with reference to the foregoing embodiments, it will be understood by those skilled in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some or all of the technical features may be equivalently replaced; and the modifications or the substitutions do not make the essence of the corresponding technical solutions depart from the scope of the technical solutions of the embodiments of the present invention.

Claims

1. The utility model provides a can prevent thrombi support of getting of escape, includes the tubulose support main part of fretwork, and wherein the axis department is support axle center (3), support main part inner chamber is arranged in catching thrombus (4) in the blood vessel, its characterized in that: the support main part adopts shape memory alloy pipe to form through laser cutting processing, shape memory alloy pipe surface array cuts out A type mesh (5) and B type mesh (6), be provided with first arc branch (51) in A type mesh (5), shape memory alloy pipe is stereotyped and is pipy support main part after, first arc branch (51) are bent to support axle center (3) inboard and are stereotyped for the first arc branch (7) after bending, thrombus (4) are blocked in support main part inner wall and are bent between first arc branch (7).

2. The thrombus-extraction stent capable of preventing thrombus from escaping according to claim 1, wherein: after the stent main body is shaped, the width W 'of the bent first arc-shaped branch (7) is more than the width D' of the A-shaped mesh (5).

3. The thrombus-extraction stent capable of preventing thrombus from escaping according to claim 1, wherein: the shape memory alloy stent is characterized in that a second arc-shaped branch (61) and a third arc-shaped branch (62) are arranged in the B-shaped mesh (6), after the shape memory alloy tube is shaped into a tubular stent main body, the second arc-shaped branch (61) and the third arc-shaped branch (62) are bent towards the inner side of the stent axis (3) and shaped into a bent second arc-shaped branch (8) and a bent third arc-shaped branch (9), and the thrombus (4) is clamped between the inner wall of the stent main body and the bent second arc-shaped branch (8) and the bent third arc-shaped branch (9).

4. The thrombus-extraction stent capable of preventing thrombus from escaping according to claim 3, wherein: in the shaped bracket main body, a bent third arc-shaped branch (9) of the B-shaped mesh hole (6) is positioned on the side close to the axis of a bent second arc-shaped branch (8).

5. The thrombus removal stent capable of preventing thrombus from escaping according to claim 1 or 3, wherein: the support main part adopts the heat setting mould to carry out high temperature heat treatment, finalizes the design and becomes barreled supporting structure, uses frock to carry out in proper order to the inboard design of axle center in first arc branch (51) of A type mesh (5), or second arc branch (61) and third arc branch (62) of B type mesh (6) again to carry out secondary heat treatment, forms the structure of support main part.

6. The thrombectomy stent capable of preventing thrombus escape according to claim 5, wherein: the main body of the bracket can be directly cut by a shape memory alloy sheet and curled and shaped into a straight hollow structure.