CN115553830B - Tumor safety sampling device - Google Patents
Tumor safety sampling device Download PDFInfo
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- CN115553830B CN115553830B CN202211393837.8A CN202211393837A CN115553830B CN 115553830 B CN115553830 B CN 115553830B CN 202211393837 A CN202211393837 A CN 202211393837A CN 115553830 B CN115553830 B CN 115553830B
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- 238000005070 sampling Methods 0.000 title claims abstract description 136
- 206010028980 Neoplasm Diseases 0.000 title claims abstract description 32
- 230000007246 mechanism Effects 0.000 claims abstract description 84
- 238000003825 pressing Methods 0.000 claims abstract description 56
- 230000008602 contraction Effects 0.000 claims abstract description 17
- 230000005540 biological transmission Effects 0.000 claims description 22
- 238000003780 insertion Methods 0.000 claims description 7
- 230000037431 insertion Effects 0.000 claims description 7
- 238000002955 isolation Methods 0.000 claims description 6
- 230000000712 assembly Effects 0.000 claims description 3
- 238000000429 assembly Methods 0.000 claims description 3
- 230000002093 peripheral effect Effects 0.000 claims description 3
- 230000000694 effects Effects 0.000 abstract description 5
- 238000009434 installation Methods 0.000 abstract description 4
- 238000001356 surgical procedure Methods 0.000 description 6
- 238000010586 diagram Methods 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 238000001959 radiotherapy Methods 0.000 description 3
- 210000004881 tumor cell Anatomy 0.000 description 3
- 238000013461 design Methods 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 238000012084 abdominal surgery Methods 0.000 description 1
- 238000001574 biopsy Methods 0.000 description 1
- 210000000481 breast Anatomy 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 210000000038 chest Anatomy 0.000 description 1
- 238000002648 combination therapy Methods 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 210000002615 epidermis Anatomy 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000009545 invasion Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 230000001575 pathological effect Effects 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
- A61B10/02—Instruments for taking cell samples or for biopsy
- A61B10/0233—Pointed or sharp biopsy instruments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
- A61B10/02—Instruments for taking cell samples or for biopsy
- A61B10/0233—Pointed or sharp biopsy instruments
- A61B10/0266—Pointed or sharp biopsy instruments means for severing sample
Abstract
The invention discloses a tumor safe sampling device, which comprises a pressing driving device and a safe sampling device; the sampling device comprises a sampling driving mechanism, a safety protection mechanism and a sampling buffer mechanism; the pressing driving device is arranged at the top of the sampling driving mechanism; the sampling driving mechanism is inserted into the safety protection mechanism; the sampling buffer mechanism is arranged in the safety protection mechanism and is connected with the sampling driving mechanism; the needle at the bottom of the sampling buffer mechanism extends out of the inner cavity of the safety protection mechanism. The sampling driving mechanism is flexibly controlled by the pressing driving assembly; the sampling driving mechanism is buckled and installed with the top of the sampling buffer mechanism in a buckling installation mode, so that the connection is stable; the sampling buffer mechanism is arranged in the safety protection mechanism and is used for extracting a tumor sample; the sampling buffer mechanism is also internally provided with a contraction component for secondary protection, so that the tumor sample taken out by the needle head is prevented from polluting the outside; the whole device is convenient to operate and good in protection effect.
Description
Technical Field
The invention relates to the technical field of tumor sampling, in particular to a tumor safe sampling device.
Background
Oncology is a secondary discipline of clinical medicine, and is classified into oncology, oncology radiotherapy, oncology surgery and the like, and oncology mainly performs internal medicine treatment of various benign and malignant tumors; the oncology radiotherapy department mainly engages in the radiotherapy of tumors; oncology surgery provides a surgical-based comprehensive treatment. The relevant departments of the special oncology hospitals can be subdivided according to different parts, such as gastroenterology and lymphomataceae in oncology; the tumor surgery includes breast surgery, head and neck surgery, chest surgery, tumor gynecology, abdominal surgery, etc. The treatment of tumors has entered the era of comprehensive treatment, and clinical practice proves that the best effect is very difficult to obtain by adopting any single treatment method at the present stage. Thus, the treatment principle for most tumors is combination therapy, except for some early tumors and individual specific types of tumors. The concept of comprehensive treatment is to apply the existing treatment means in a planned and reasonable way according to the organism condition of the patient, the pathological type of the tumor, the invasion range (disease period) and the development trend, so as to greatly improve the cure rate of the tumor, prolong the life time and improve the life quality of the patient.
In the existing oncology treatment process, the living tumor tissue must be sampled; the existing tumor sampling device is inconvenient to operate, difficult to cut, troublesome to operate and time-consuming and labor-consuming when performing tumor biopsy cutting on a patient when sampling, the working difficulty of medical staff is increased, the taken sample not only comprises tumor cells, but also comprises partial epidermis and muscle tissues, the pureness of the sample is influenced to a certain extent, and the existing sampling device is used repeatedly, so that the risk of mutual infection among users exists.
Therefore, there is a need to design a tumor safe sampling device with good protection effect.
Disclosure of Invention
The invention aims to provide a tumor safe sampling device which solves the problems existing in the prior art.
In order to achieve the above object, the present invention provides the following solutions: the invention provides a tumor safe sampling device, which comprises: a pressing driving device and a safety sampling device; the sampling device comprises a sampling driving mechanism, a safety protection mechanism and a sampling buffer mechanism; the pressing driving device is arranged at the top of the sampling driving mechanism; the sampling driving mechanism is inserted into the safety protection mechanism; the sampling buffer mechanism is arranged in the safety protection mechanism and is connected with the sampling driving mechanism; and a needle at the bottom of the sampling buffer mechanism extends out of the inner cavity of the safety protection mechanism.
The pressing driving device comprises a pressing handle, wherein the pressing handle comprises an operation part and a pressing grabbing part; the operation part comprises a balancing weight and a pressing key; one end of a first operation rod is fixedly connected to the pressing key; the other end of the first operating rod extends into the operating part and is in transmission connection with a second operating rod of the pressing grabbing part through a transmission rod;
a first limiting ring and a second limiting ring are respectively formed on the middle part of the side wall of the first operating rod and the middle part of the side wall of the second operating rod; a first elastic piece is arranged between the first limiting ring and the pressing key; the first elastic piece is sleeved on the first operating rod; the end part of the first operating rod is rotationally connected with one end of the transmission rod through a rotating shaft; the pressing handle is also provided with a movable groove; a sliding rod is fixedly arranged in the middle of the transmission rod; the sliding rod is arranged in the movable groove in a sliding way and is used for adjusting the transmission center of the transmission rod; the other end of the transmission rod is rotationally connected with one end of the second operation rod through the rotating shaft; the other end of the second operating rod is inserted into the sampling driving mechanism and is fixedly connected with the sampling driving mechanism.
A side wall of the pressing grabbing part also extends outwards to form an inserting wall; the plug-in wall is of a hollow cylindrical structure; the movable side of the insertion wall is inserted into the sampling driving mechanism; the side wall of the pressing grabbing part extends inwards to form a grabbing groove; the diameter of the notch of the grabbing groove is smaller than that of the second limiting ring; the second operating rod extends out of the grabbing groove, and a plurality of inserting rods are fixedly arranged at the extending end of the second operating rod; the movable end of the insertion connection rod is provided with a spherical hinge.
The sampling driving mechanism comprises a first shell; an annular inserting groove matched with the inserting wall is formed at the top of the first shell; the first shell is hollow; an adjusting groove is formed on the bottom surface of the first shell in an inward concave manner; the center of the bottom surface of the adjusting tank is provided with a mounting hole, and the mounting hole extends upwards to penetrate through the center of the top surface of the first shell; a first driving piece is arranged at the top of the first shell; the top surface of the first driving piece is provided with a fixing groove downwards; the bottom surface of the fixed groove extends downwards to form a spherical hinge groove matched with the plug rod;
a thread groove is formed in the center of the bottom surface of the first driving piece; a second driving piece is arranged in the thread groove of the first driving piece.
The second driving piece comprises a first connecting rod; the top of the first connecting rod is in threaded connection with the first driving piece, and the bottom of the first connecting rod extends out of the mounting hole and is fixedly provided with a second connecting rod; the second connecting rod is gradually increased in wall from top to bottom, and the second connecting rod is hollow; one end of the bottom surface of the second connecting rod protrudes downwards to form a sharp bulge; a hollowed-out groove is formed in the other side of the bottom surface of the second connecting rod inwards, and the hollowed-out groove is communicated with the inner cavity of the second connecting rod; a first supporting plate is formed on the intersection surface of the sharp bulge and the hollowed-out groove; the movable end of the first supporting plate is fixedly connected with one end of a semicircular plate; a second supporting plate is fixedly arranged at the other end of the semicircular plate; the second supporting plate, the semicircular plate and the first supporting plate divide the inner cavity of the second connecting rod into a first inner cavity and a second inner cavity; an arc chute is formed in the middle of the peripheral wall of the semicircular plate; a semicircular block is arranged in the semicircular plate; a restoration block is fixedly arranged at one end of the outer wall of the semicircular block; the restoration block is arranged in the arc-shaped chute in a sliding manner, penetrates through the inner wall of the second connecting rod and is arranged in the adjusting groove; the outer wall of the second connecting rod is provided with a through groove corresponding to the arc chute in position; a concave area which is positioned at the position of the restoration block is formed in the adjusting groove; one end of the second elastic piece is arranged in the middle of the restoration block; the second elastic piece penetrates through the first inner cavity and the second inner cavity and is fixedly arranged in the middle of the inner wall of the second connecting rod.
The sampling buffer mechanism comprises a first driven piece which is spliced with the second driving piece; the first driven piece comprises the sharp protrusion with the same structure as the second driving piece, a first supporting plate, a second supporting plate, a semicircular plate and a semicircular block; the second driving piece and the first driven piece are symmetrical about the center of the intersection line of the two first supporting plates; a driven block is fixedly arranged at one end of the outer wall of the semicircular block of the first driven piece; the outer wall of the first driven piece is provided with a through groove corresponding to the arc chute in position, and the driven block is arranged in the through groove; one end of a third elastic piece is arranged in the middle of the driven block; the third elastic piece is fixedly arranged in the middle of the inner wall of the first driven piece;
the bottom of the first driven piece is fixedly provided with a second driven piece; an outer sampling tube is arranged at the joint of the first driven piece and the second driven piece; an annular plate is fixedly arranged at the top of the outer wall of the outer sampling tube; an annular groove is formed in the bottom of the annular plate upwards; a plurality of fourth elastic pieces are arranged on the bottom surface of the annular groove at equal intervals; the movable ends of the fourth elastic pieces are provided with movable blocks; the movable block is limited in the annular groove; the movable block corresponds to the supporting ring of the safety protection mechanism in position.
The bottom surface of the outer sampling tube is hollowed out, and a plurality of inner bulges are formed inwards on the bottom surface of the outer sampling tube; the second driven piece is arranged in the outer sampling tube, and a safety isolation assembly is arranged at the bottom of the second driven piece; and a buffer cavity is formed in the second driven piece.
The safety isolation assembly comprises a limiting block and an inner sampling tube; the top of the inner sampling tube is arranged at the bottom of the second driven piece through a limiting block; at least one group of contraction components are arranged on the outer wall of the inner sampling tube; each group of the contraction assemblies comprises two contraction pieces and two mounting seats; the two shrinkage parts are respectively rotatably installed on the installation seat through the rotating shaft; and the two contraction pieces are symmetrical about the center of the inner sampling tube;
the contraction piece comprises a hook body part and an inclined part; one end of the hook body part and one end of the inclined part are respectively rotatably arranged at two sides of the rotating shaft; the hook body part is arranged below the inclined part; the top end of the inclined part is elastically connected with the top of the inner sampling tube through a fifth elastic piece; when the bottom of the hook body is horizontally arranged, the bottom of the hook body is flush with the inner end point of the inner protrusion; a chassis is supported on the inner sides of the plurality of hook body parts; the chassis cover is arranged at the bottom of the connecting sleeve; the connecting sleeve comprises a plurality of sequentially stacked lantern rings; the top of the connecting sleeve is arranged on the bottom surface of the inner sampling tube; guide rings are also arranged at the two ends of the inner side of the connecting sleeve; a guide hole is formed in the center of the guide ring; the center of the bottom surface of the inner sampling tube and the center of the chassis are provided with perforations; the needle head, the guide ring and the perforation which are arranged on the bottom surface of the inner sampling tube are arranged on the same axis.
The safety protection mechanism further comprises a second shell; a supporting table is fixedly arranged on the inner wall of the second shell; the supporting ring is arranged at the top of the supporting table; the support ring has a cross-sectional area smaller than the movable block.
And the bottom of the second shell is provided with a rubber sleeve which is abutted with the outer sampling tube.
The invention discloses the following technical effects: the sampling driving mechanism is flexibly controlled by the pressing driving assembly; the sampling driving mechanism is buckled and installed with the top of the sampling buffer mechanism in a buckling installation mode, so that the connection is stable; the sampling buffer mechanism is arranged in the safety protection mechanism and is used for extracting a tumor sample; the sampling buffer mechanism is also internally provided with a contraction component for secondary protection, so that the tumor sample taken out by the needle head is prevented from polluting the outside; the whole device is convenient to operate and good in protection effect.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions of the prior art, the drawings that are needed in the embodiments will be briefly described below, it being obvious that the drawings in the following description are only some embodiments of the present invention, and that other drawings may be obtained according to these drawings without inventive effort for a person skilled in the art.
FIG. 1 is a schematic diagram of the overall structure;
FIG. 2 is a schematic diagram of a press driving device;
FIG. 3 is a schematic diagram of a safety sampling device;
FIG. 4 is an enlarged view of the structure at A of FIG. 3;
wherein, 1, pressing the driving device; 2. a sampling driving mechanism; 3. a safety protection mechanism; 4. A sampling buffer mechanism; 5. a needle; 6. an outer sampling tube; 7. a rubber sleeve; 11. pressing the handle; 12. balancing weight; 13. pressing a key; 14. a first lever; 15. a transmission rod; 16. a second lever; 17. a first stop collar; 18. a second limiting ring; 19. a first elastic member; 110. A movable groove; 111. a slide bar; 112. a plug wall; 113. inserting a connecting rod; 21. a first housing; 22. an annular insertion groove; 23. an adjustment groove; 24. a first driving member; 25. a fixing groove; 26. A spherical hinge groove; 27. a second driving member; 31. a second connecting rod; 32. a sharp protrusion; 33. a first support plate; 34. a semicircular plate; 35. a second support plate; 36. an arc chute; 37. a semicircle block; 38. restoring the block; 39. a through groove; 310. a second elastic member; 311. a first connecting rod; 41. a first follower; 42. a driven block; 43. a third elastic member; 44. a second follower; 45. an annular plate; 46. an annular groove; 47. a fourth elastic member; 48. a movable block; 61. an inner protrusion; 62. a limiting block; 63. an inner sampling tube; 64. a mounting base; 65. a fifth elastic member; 66. A chassis; 67. connecting the sleeves; 68. a guide ring; 71. a support ring; 72. a second housing; 73. and a support table.
Detailed Description
The following description of the embodiments of the present invention will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
In order that the above-recited objects, features and advantages of the present invention will become more readily apparent, a more particular description of the invention will be rendered by reference to the appended drawings and appended detailed description.
The invention provides a tumor safe sampling device, which comprises: a pressing drive device 1 and a safety sampling device; the sampling device comprises a sampling driving mechanism 2, a safety protection mechanism 3 and a sampling buffer mechanism 4; the pressing driving device 1 is arranged at the top of the sampling driving mechanism 2; the sampling driving mechanism 2 is inserted into the safety protection mechanism 3; the sampling buffer mechanism 4 is arranged in the safety protection mechanism 3, and the sampling buffer mechanism 4 is connected with the sampling driving mechanism 2; the needle 5 at the bottom of the sampling buffer mechanism 4 extends out of the inner cavity of the safety protection mechanism 3.
The pressing drive device 1 includes a pressing handle 11, the pressing handle 11 including an operation portion and a pressing grasping portion; the operation part comprises a balancing weight 12 and a pressing key 13; one end of a first operating rod 14 is fixedly connected to the pressing key 13; the other end of the first operating rod 14 extends into the operating part and is in transmission connection with a second operating rod 16 pressing the grabbing part through a transmission rod 15;
a first limiting ring 17 and a second limiting ring 18 are respectively formed on the middle part of the side wall of the first operating rod 14 and the middle part of the side wall of the second operating rod 16; a first elastic piece 19 is arranged between the first limiting ring 17 and the pressing key 13; the first elastic piece 19 is sleeved on the first operating rod 14; the end part of the first operating rod 14 is rotationally connected with one end of a transmission rod 15 through a rotating shaft; the pressing handle 11 is also provided with a movable groove 110; a slide bar 111 is fixedly arranged in the middle of the transmission rod 15; the sliding rod 111 is slidably arranged in the movable groove 110 and is used for adjusting the transmission center of the transmission rod 15; the other end of the transmission rod 15 is rotationally connected with one end of a second operation rod 16 through a rotating shaft; the other end of the second operating rod 16 is inserted into the sampling driving mechanism 2 and is fixedly connected with the sampling driving mechanism 2.
A side wall of the pressing grabbing part is also outwards extended to form a plugging wall 112; the plug wall 112 is of a hollow cylindrical structure; the movable side of the insertion wall 112 is inserted into the sampling driving mechanism 2; the side wall of the pressing grabbing part extends inwards to form a grabbing groove; the diameter of the notch of the grabbing groove is smaller than that of the second limiting ring 18; the second operating rod 16 extends out of the grabbing groove, and a plurality of inserting rods 113 are fixedly arranged at the extending end of the second operating rod 16; the movable end of the insertion rod 113 is provided with a spherical hinge.
In one embodiment of the invention, the pressing grabbing part of the pressing driving device 1 is matched with the first shell 221 of the sampling driving mechanism, the positioning between the two devices is realized by matching the plugging wall 112 with the annular plugging groove 22 on the top surface of the first shell 21, and meanwhile, the spherical hinge at the movable end of the plugging rod 113 stretches into the spherical hinge groove 26 to realize the matched installation of the two devices; further, the operator holds the pressing handle 11 with the palm and presses the pressing key 13 with the finger portion; the pressing key 13 is pressed to move upwards, and the first operating rod 14 is pushed to move upwards at the moment; the first movable lever 14 and the second operation lever 16 are height-adjusted with the slide lever 111 as a rotation center, and thus the second operation lever 16 lifts the sampling driving mechanism 2.
Further, the first elastic member 19 is used for resetting the first movable lever 14.
Further, the weight block is to balance the weight of the pressing driving part, so that the worker can ensure the balance of both ends when holding the pressing handle 11.
The sampling drive mechanism 2 includes a first housing 21; the top of the first shell 21 is provided with an annular inserting groove 22 matched with the inserting wall 112; the first housing 21 is hollow inside; the bottom surface of the first shell 21 is concavely formed with an adjusting groove 23; the center of the bottom surface of the adjusting groove 23 is provided with a mounting hole which extends upwards to penetrate through the center of the top surface of the first shell 21; the top of the first housing 21 is provided with a first driving member 24; the top surface of the first driving piece 24 is provided with a fixing groove 25 downwards; the bottom surface of the fixed groove 25 extends downwards to form a fixed groove 25 which is matched with the inserting connection rod 113; the bottom of the fixed groove 25 is provided with a spherical hinge groove 26 in a downward extending way;
a thread groove is formed in the center of the bottom surface of the first driving piece 24; a second driver 27 is mounted in the thread groove of the first driver 24.
The second driving member 27 includes a first connecting rod 311; the top of the first connecting rod 311 is in threaded connection with the first driving piece 24, and the bottom of the first connecting rod 311 extends out of the mounting hole and is fixedly provided with a second connecting rod 31; the second connecting rod 31 gradually increases from top to bottom, and the second connecting rod 31 is hollow; one end of the bottom surface of the second connecting rod 31 protrudes downwards to form a sharp protrusion 32; the other side of the bottom surface of the second connecting rod 31 is internally provided with a hollow groove which is communicated with the inner cavity of the second connecting rod 31; a first supporting plate 33 is formed on the intersection surface of the sharp protrusion 32 and the hollowed-out groove; the movable end of the first supporting plate 33 is fixedly connected with one end of a semicircular plate 34; the other end of the semicircular plate 34 is fixedly provided with a second supporting plate 35; a second support plate 35, a semicircular plate 34 and a first support plate 33 divide the inner cavity of the second connecting rod 31 into a first inner cavity and a second inner cavity; an arc chute 36 is formed in the middle of the peripheral wall of the semicircular plate 34; a semicircular block 37 is arranged in the semicircular plate 34; a restoration block 38 is fixedly arranged at one end of the outer wall of the semicircular block 37; the restoring block 38 is slidably arranged in the arc-shaped chute 36, and the restoring block 38 penetrates through the inner wall of the second connecting rod 31 and is arranged in the adjusting groove 23; the outer wall of the second connecting rod 31 is provided with a through groove 39 corresponding to the arc chute 36 in position; a concave area which is positioned at the position of the restoring block 38 is formed in the adjusting groove 23; one end of the second elastic member 310 is installed at the middle of the restoring block 38; the second elastic member 310 is fixedly installed in the middle of the inner wall of the second connecting rod 31 through the first and second inner cavities.
In one embodiment of the present invention, the first driving member 24 is screwed with the first connecting rod 311 of the second driving member 27; one end of the first connecting rod 311 extends into the adjusting groove 23 and is connected with a second connecting rod 31; the second connecting rod 31 is internally divided into two sides of the inner cavity by a second supporting plate 35, a semicircular plate 34 and a first supporting plate 33, and a semicircular block 37 in an arc chute 36 of the second connecting rod rotates along the arc chute 36;
further, when the second connecting rod 31 is assembled and buckled with the first driven member 41, the sharp protrusions 32 on the second connecting rod 31 and the first driven member 41 are mutually inserted into the second inner cavity of each other along the vertical direction; the sharp protrusion 32 will abut against the semicircular block 37 (or the driven block 42) during the insertion process, so as to push the semicircular block 37 to rotate in the arc chute 36; at this time, the restoring block 38 moves in an arc-shaped curve along with the semicircular block 37 (or the driven block 42); the end surfaces of the semicircular block 37 and the driven block 42 are parallel to the second supporting plate 35 before the second connecting rod 31 and the first driven member 41 are assembled and buckled; when the second connecting rod 31 and the first driven member 41 are assembled and fastened, the semicircular block 37 and the driven block 42 are restored to the front angle before being fastened, and the two restoring blocks 38 are restored to the initial positions.
Further, the third elastic member 43 and the second elastic member 310 are used for restoring the positions of the two restoring blocks 38, respectively.
The sampling buffer mechanism 4 comprises a first driven piece 41 which is spliced with the second driving piece 27; the first follower 41 includes a sharp projection 32 having the same structure as the second driver 27, a first support plate 33, a second support plate 35, a semicircular plate 34 and a semicircular block 37; the second driving member 27 and the first driven member 41 are symmetrical about the intersection line center of the two first supporting plates 33; a driven block 42 is fixedly arranged at one end of the outer wall of the semicircular block 37 of the first driven member 41; the outer wall of the first follower 41 is provided with a through groove 39 corresponding to the position of the arc chute 36, and the follower block 42 is arranged in the through groove 39; one end of a third elastic piece 43 is arranged in the middle of the driven block 42; the third elastic member 43 is fixedly installed in the middle of the inner wall of the first follower 41;
the bottom of the first follower 41 is fixedly provided with a second follower 44; the connection part of the first driven piece 41 and the second driven piece 44 is provided with an outer sampling tube 6; the top of the outer wall of the outer sampling tube 6 is fixedly provided with an annular plate 45; the bottom of the annular plate 45 is provided with an annular groove 46 upwards; a plurality of fourth elastic pieces 47 are arranged on the bottom surface of the annular groove 46 at equal intervals; the movable ends of the fourth elastic pieces 47 are provided with movable blocks 48; a movable block 48 is defined within the annular groove 46; the movable block 48 corresponds in position to the support ring 71 of the safety shield mechanism 3.
In one embodiment of the present invention, the middle portion of the outer wall of the first housing 21 is shrunk inwards to form a closing surface, and the radian of the outer wall of the first housing 21 is the same as that of the inner wall of the second housing 72.
The bottom surface of the outer sampling tube 6 is hollowed out, and a plurality of inner bulges 61 are formed inwards on the bottom surface of the outer sampling tube 6; the second follower 44 is arranged in the outer sampling tube 6, and a safety isolation assembly is arranged at the bottom of the second follower 44; the second follower 44 has a buffer cavity formed therein.
The safety isolation assembly comprises a limiting block 62 and an inner sampling tube 63; the top of the inner sampling tube 63 is arranged at the bottom of the second driven piece 44 through a limiting block 62; at least one group of contraction components are arranged on the outer wall of the inner sampling tube 63; each set of retraction assemblies includes two retraction members and two mounting seats 64; the two contraction pieces are respectively and rotatably arranged on the mounting seat 64 through the rotating shaft; and the two contraction pieces are symmetrical about the center of the inner sampling tube 63;
the contraction piece comprises a hook body part and an inclined part; one end of the hook body part and one end of the inclined part are respectively rotatably arranged at two sides of the rotating shaft; the hook body part is arranged below the inclined part; the top end of the inclined part is elastically connected with the top of the inner sampling tube 63 through a fifth elastic piece 65; when the bottom of the hook body is horizontally arranged, the bottom is flush with the inner end point of the inner bulge 61; the inner sides of the hook bodies are supported with a chassis 66; the chassis 66 is covered at the bottom of the connecting sleeve 67; the connecting sleeve 67 comprises a plurality of sequentially stacked lantern rings; the top of the connecting sleeve 67 is arranged on the bottom surface of the inner sampling tube 63; guide rings 68 are also arranged at both ends of the inner side of the connecting sleeve 67; a guide hole is formed in the center of the guide ring 68; the center of the bottom surface of the inner sampling tube 63 and the center of the chassis 66 are provided with perforations; the needle 5 mounted on the bottom surface of the inner barrel 63 is co-axially aligned with the guide ring 68 and the bore.
In one embodiment of the present invention, as shown in fig. 4, after the second connecting rod 31 is assembled with the first driven member 41, the second connecting rod 31 moves downward by continuing to press the pressing driving device 1, and the first driven member 41 moves synchronously with the second connecting rod 31; at this time, the first follower 41 presses the inner sampling tube 63 downward through the second follower 44, and at this time, the contracting member is driven to move outwards of the outer sampling tube 6; meanwhile, the contraction piece rotates around the mounting seat 64 as a center, and is flush with the inner end point of the inner bulge 61 when the bottom of the hook body part of the contraction piece is horizontally arranged; when the structure body extends out of the outer sampling tube 6, the inclined part contracts inwards; at this time, the chassis 66 is discharged, and the connecting sleeves 67 on the two sides of the guide ring 68 are discharged; when the needle 5 is sampled, the connecting sleeve 67 completely wraps the needle 5 to prevent the tumor cells from leaking; then, when retracted, the hub 67 and needle 5 are fully wrapped around the retraction inner barrel 63.
The safety shield mechanism 3 further includes a second housing 72; a supporting table 73 is fixedly arranged on the inner wall of the second shell 72; a support ring 71 is arranged on the top of the support table 73; the support ring 71 has a smaller cross-sectional area than the movable block 48.
In one embodiment of the present invention, the second housing 72 is used to isolate the outer sampling tube 6 from the inner sampling tube 63 for storage, preventing contamination of tumor cells; the annular plate 45 on the outer wall of the outer sampling tube 6 corresponds to the supporting table 73 formed in the second shell 72 in position, so that the limiting support of the movable block 48 and the supporting ring 71 at the bottommost end is realized.
The rubber sleeve 7 abutting against the outer sampling tube 6 is mounted at the bottom of the second shell 72.
In the description of the present invention, it should be understood that the terms "longitudinal," "transverse," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," and the like indicate or are based on the orientation or positional relationship shown in the drawings, merely to facilitate description of the present invention, and do not indicate or imply that the devices or elements referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus should not be construed as limiting the present invention.
The above embodiments are only illustrative of the preferred embodiments of the present invention and are not intended to limit the scope of the present invention, and various modifications and improvements made by those skilled in the art to the technical solutions of the present invention should fall within the protection scope defined by the claims of the present invention without departing from the design spirit of the present invention.
Claims (7)
1. A tumor safety sampling device, comprising: a pressing driving device (1) and a safety sampling device; the sampling device comprises a sampling driving mechanism (2), a safety protection mechanism (3) and a sampling buffer mechanism (4); the pressing driving device (1) is arranged at the top of the sampling driving mechanism (2); the sampling driving mechanism (2) is inserted into the safety protection mechanism (3); the sampling buffer mechanism (4) is arranged in the safety protection mechanism (3), and the sampling buffer mechanism (4) is connected with the sampling driving mechanism (2); a needle head (5) at the bottom of the sampling buffer mechanism (4) extends out of the inner cavity of the safety protection mechanism (3); the sampling driving mechanism (2) comprises a first shell (21); an annular inserting groove (22) matched with an inserting wall (112) in the pressing driving device (1) is formed at the top of the first shell (21); the first shell (21) is hollow inside; an adjusting groove (23) is formed on the bottom surface of the first shell (21) in an inward concave manner; a mounting hole is formed in the center of the bottom surface of the adjusting groove (23), and extends upwards to penetrate through the center of the top surface of the first shell (21); a first driving piece (24) is arranged at the top of the first shell (21); the top surface of the first driving piece (24) is provided with a fixing groove (25) downwards; a spherical hinge groove (26) matched with the inserting connection rod (113) of the pressing driving device (1) is formed in the downward extension of the bottom surface of the fixing groove (25);
a thread groove is formed in the center of the bottom surface of the first driving piece (24); a second driving piece (27) is arranged in the thread groove of the first driving piece (24); the second driving piece (27) comprises a first connecting rod (311); the top of the first connecting rod (311) is in threaded connection with the first driving piece (24), and the bottom of the first connecting rod (311) extends out of the mounting hole and is fixedly provided with a second connecting rod (31); the second connecting rod (31) gradually increases from top to bottom, and the second connecting rod (31) is hollow; one end of the bottom surface of the second connecting rod (31) protrudes downwards to form a sharp protrusion (32); a hollowed-out groove is formed in the other side of the bottom surface of the second connecting rod (31) inwards, and the hollowed-out groove is communicated with the inner cavity of the second connecting rod (31); a first supporting plate (33) is formed on the intersection surface of the sharp bulge (32) and the hollowed-out groove; one end of a semicircular plate (34) is fixedly connected with the movable end of the first supporting plate (33); a second supporting plate (35) is fixedly arranged at the other end of the semicircular plate (34); the second supporting plate (35), the semicircular plate (34) and the first supporting plate (33) divide the inner cavity of the second connecting rod (31) into a first inner cavity and a second inner cavity; an arc chute (36) is formed in the middle of the peripheral wall of the semicircular plate (34); a semicircular block (37) is arranged in the semicircular plate (34); a restoration block (38) is fixedly arranged at one end of the outer wall of the semicircular block (37); the restoration block (38) is arranged in a sliding way in the arc-shaped chute (36), and the restoration block (38) penetrates through the inner wall of the second connecting rod (31) and is arranged in the adjusting groove (23); a through groove (39) corresponding to the arc chute (36) in position is formed in the outer wall of the second connecting rod (31); a concave area which is positioned at the position of the restoring block (38) is formed in the adjusting groove (23); one end of a second elastic piece (310) is arranged in the middle of the restoring block (38); the second elastic piece (310) penetrates through the first inner cavity and the second inner cavity and is fixedly arranged in the middle of the inner wall of the second connecting rod (31); the sampling buffer mechanism (4) comprises a first driven piece (41) which is spliced with the second driving piece (27); the first driven member (41) comprises the sharp protrusion (32) which has the same structure as the second driving member (27), a first supporting plate (33), a second supporting plate (35), a semicircular plate (34) and a semicircular block (37); the second driving piece (27) and the first driven piece (41) are symmetrical about the intersection line center of the two first supporting plates (33); a driven block (42) is fixedly arranged at one end of the outer wall of the semicircular block (37) of the first driven piece (41); the outer wall of the first driven piece (41) is provided with a through groove (39) corresponding to the arc chute (36), and the driven block (42) is arranged in the through groove (39); one end of a third elastic piece (43) is arranged in the middle of the driven block (42); the third elastic piece (43) is fixedly arranged in the middle of the inner wall of the first driven piece (41);
the bottom of the first driven piece (41) is fixedly provided with a second driven piece (44); an outer sampling tube (6) is arranged at the joint of the first driven piece (41) and the second driven piece (44); an annular plate (45) is fixedly arranged at the top of the outer wall of the outer sampling tube (6); an annular groove (46) is formed in the bottom of the annular plate (45) upwards; a plurality of fourth elastic pieces (47) are arranged on the bottom surface of the annular groove (46) at equal intervals; the movable ends of the fourth elastic pieces (47) are provided with movable blocks (48); -said movable block (48) being defined within said annular groove (46); the movable block (48) corresponds to the position of the supporting ring (71) of the safety protection mechanism (3).
2. The tumor safe sampling apparatus according to claim 1, wherein: the pressing driving device (1) comprises a pressing handle (11), wherein the pressing handle (11) comprises an operation part and a pressing grabbing part; the operation part comprises a balancing weight (12) and a pressing key (13); one end of a first operating rod (14) is fixedly connected to the pressing key (13); the other end of the first operating rod (14) stretches into the operating part and is in transmission connection with a second operating rod (16) pressing the grabbing part through a transmission rod (15);
a first limiting ring (17) and a second limiting ring (18) are respectively formed on the middle part of the side wall of the first operating rod (14) and the middle part of the side wall of the second operating rod (16); a first elastic piece (19) is arranged between the first limiting ring (17) and the pressing key (13); the first elastic piece (19) is sleeved on the first operating rod (14); the end part of the first operating rod (14) is rotationally connected with one end of the transmission rod (15) through a rotating shaft; the pressing handle (11) is also provided with a movable groove (110); a sliding rod (111) is fixedly arranged in the middle of the transmission rod (15); the sliding rod (111) is arranged in the movable groove (110) in a sliding way and is used for adjusting the transmission center of the transmission rod (15); the other end of the transmission rod (15) is rotationally connected with one end of the second operation rod (16) through the rotating shaft; the other end of the second operating rod (16) is inserted into the sampling driving mechanism (2) and is fixedly connected with the sampling driving mechanism (2).
3. The tumor safe sampling apparatus according to claim 2, wherein: a side wall of the pressing grabbing part is also outwards extended to form an inserting wall (112); the plug-in wall (112) is of a hollow cylindrical structure; the movable side of the insertion wall (112) is inserted into the sampling driving mechanism (2); the side wall of the pressing grabbing part extends inwards to form a grabbing groove; the diameter of the notch of the grabbing groove is smaller than that of the second limiting ring (18); the second operation rod (16) extends out of the grabbing groove, and a plurality of inserting rods (113) are fixedly arranged at the extending end of the second operation rod (16); the movable end of the plug-in rod (113) is provided with a spherical hinge.
4. The tumor safe sampling apparatus according to claim 1, wherein: the bottom surface of the outer sampling tube (6) is hollowed out, and a plurality of inner bulges (61) are formed inwards on the bottom surface of the outer sampling tube (6); the second driven piece (44) is arranged in the outer sampling tube (6), and a safety isolation assembly is arranged at the bottom of the second driven piece (44); a buffer cavity is formed in the second driven piece (44).
5. The tumor safe sampling apparatus according to claim 4, wherein: the safety isolation assembly comprises a limiting block (62) and an inner sampling tube (63); the top of the inner sampling tube (63) is arranged at the bottom of the driven piece (44) through a limiting block (62); at least one group of contraction components are arranged on the outer wall of the inner sampling tube (63); each set of said retraction assemblies comprising two retraction members and two mounting blocks (64); the two contraction pieces are respectively and rotatably arranged on the mounting seat (64) through a rotating shaft; and the two contractions are symmetrical about the center of the inner sampling tube (63);
the contraction piece comprises a hook body part and an inclined part; one end of the hook body part and one end of the inclined part are respectively rotatably arranged at two sides of the rotating shaft; the hook body part is arranged below the inclined part; the top end of the inclined part is elastically connected with the top of the inner sampling tube (63) through a fifth elastic piece (65); when the bottom of the hook body is horizontally arranged, the bottom is flush with the inner end point of the inner protrusion (61); a chassis (66) is supported on the inner sides of the plurality of hook body parts; the chassis (66) is covered at the bottom of the connecting sleeve (67); the connecting sleeve (67) comprises a plurality of sequentially stacked lantern rings; the top of the connecting sleeve (67) is arranged on the bottom surface of the inner sampling tube (63); guide rings (68) are also arranged at the two ends of the inner side of the connecting sleeve (67); a guide hole is formed in the center of the guide ring (68); the center of the bottom surface of the inner sampling tube (63) and the center of the chassis (66) are provided with perforations; the needle (5) arranged on the bottom surface of the inner sampling tube (63) is arranged on the same axis with the guide ring (68) and the perforation.
6. The tumor safe sampling apparatus according to claim 5, wherein: the safety protection mechanism (3) also comprises a second shell (72); a supporting table (73) is fixedly arranged on the inner wall of the second shell (72); the top of the supporting table (73) is provided with the supporting ring (71); the support ring (71) has a cross-sectional area smaller than the movable block (48).
7. The tumor safe sampling apparatus according to claim 6, wherein: and a rubber sleeve (7) abutted with the outer sampling tube (6) is arranged at the bottom of the second shell (72).
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Citations (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5374250A (en) * | 1993-11-01 | 1994-12-20 | Dixon; Richard E. | Safety syringe |
US6540732B1 (en) * | 1998-12-15 | 2003-04-01 | Mdc Investment Holdings, Inc. | Fluid collection device with captured retractable needle |
GB201012844D0 (en) * | 2010-07-30 | 2010-09-15 | Ferrett Colin G | Body cavity sampling device |
CN206275706U (en) * | 2016-08-27 | 2017-06-27 | 薛传亭 | A kind of Novel urine collection device for checking clinic |
CN109805966A (en) * | 2019-01-31 | 2019-05-28 | 周彩凤 | A kind of oncology living body sampling feeding device for inspection |
CN209269751U (en) * | 2019-01-02 | 2019-08-20 | 王耿 | A kind of tumour living sampling device |
CN112617912A (en) * | 2021-01-08 | 2021-04-09 | 湖南省肿瘤医院 | Gynecological tumor sampling device |
CN112842407A (en) * | 2021-01-31 | 2021-05-28 | 义乌市中心医院 | Infectious department uses germ sampling device |
CN213787549U (en) * | 2020-11-25 | 2021-07-27 | 北京医院 | Collection device in bladder tumour art |
CN113288229A (en) * | 2021-05-19 | 2021-08-24 | 西安交通大学医学院第二附属医院 | A detect sampling device for breast tumour |
CN113384304A (en) * | 2021-07-13 | 2021-09-14 | 南通市肿瘤医院 | Safe type sampling device for medical oncology |
CN113520468A (en) * | 2021-06-09 | 2021-10-22 | 西安交通大学医学院第二附属医院 | Sampler for medical oncology |
WO2021243807A1 (en) * | 2020-06-02 | 2021-12-09 | 南京融康博临床医学研究院有限公司 | Tumor sampling device for lung cancer |
CN215178861U (en) * | 2021-07-23 | 2021-12-14 | 天津安恒环测科技有限公司 | Water quality monitoring sampling device |
CN215386982U (en) * | 2021-07-13 | 2022-01-04 | 成都中医药大学附属医院 | External medicine applying device |
CN216060592U (en) * | 2021-09-18 | 2022-03-18 | 李慧 | Clinical puncture sampler that uses of oncology |
CN216823528U (en) * | 2021-11-23 | 2022-06-28 | 阳信县中医医院 | Quantitative sampling device for medical oncology |
CN217219074U (en) * | 2022-05-11 | 2022-08-19 | 西安交通大学医学院第二附属医院 | Clinical sampling device of breast cancer |
CN114983489A (en) * | 2022-05-31 | 2022-09-02 | 华中科技大学同济医学院附属协和医院 | Sampling device before tumour inspection |
CN115040168A (en) * | 2022-02-08 | 2022-09-13 | 江苏省肿瘤医院 | Probe for pathological diagnosis of tumor and using method |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111493942A (en) * | 2020-05-28 | 2020-08-07 | 中国医科大学 | Medical totally-enclosed pathological sampling device |
-
2022
- 2022-11-08 CN CN202211393837.8A patent/CN115553830B/en active Active
Patent Citations (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5374250A (en) * | 1993-11-01 | 1994-12-20 | Dixon; Richard E. | Safety syringe |
US6540732B1 (en) * | 1998-12-15 | 2003-04-01 | Mdc Investment Holdings, Inc. | Fluid collection device with captured retractable needle |
GB201012844D0 (en) * | 2010-07-30 | 2010-09-15 | Ferrett Colin G | Body cavity sampling device |
CN206275706U (en) * | 2016-08-27 | 2017-06-27 | 薛传亭 | A kind of Novel urine collection device for checking clinic |
CN209269751U (en) * | 2019-01-02 | 2019-08-20 | 王耿 | A kind of tumour living sampling device |
CN109805966A (en) * | 2019-01-31 | 2019-05-28 | 周彩凤 | A kind of oncology living body sampling feeding device for inspection |
WO2021243807A1 (en) * | 2020-06-02 | 2021-12-09 | 南京融康博临床医学研究院有限公司 | Tumor sampling device for lung cancer |
CN213787549U (en) * | 2020-11-25 | 2021-07-27 | 北京医院 | Collection device in bladder tumour art |
CN112617912A (en) * | 2021-01-08 | 2021-04-09 | 湖南省肿瘤医院 | Gynecological tumor sampling device |
CN112842407A (en) * | 2021-01-31 | 2021-05-28 | 义乌市中心医院 | Infectious department uses germ sampling device |
CN113288229A (en) * | 2021-05-19 | 2021-08-24 | 西安交通大学医学院第二附属医院 | A detect sampling device for breast tumour |
CN113520468A (en) * | 2021-06-09 | 2021-10-22 | 西安交通大学医学院第二附属医院 | Sampler for medical oncology |
CN113384304A (en) * | 2021-07-13 | 2021-09-14 | 南通市肿瘤医院 | Safe type sampling device for medical oncology |
CN215386982U (en) * | 2021-07-13 | 2022-01-04 | 成都中医药大学附属医院 | External medicine applying device |
CN215178861U (en) * | 2021-07-23 | 2021-12-14 | 天津安恒环测科技有限公司 | Water quality monitoring sampling device |
CN216060592U (en) * | 2021-09-18 | 2022-03-18 | 李慧 | Clinical puncture sampler that uses of oncology |
CN216823528U (en) * | 2021-11-23 | 2022-06-28 | 阳信县中医医院 | Quantitative sampling device for medical oncology |
CN115040168A (en) * | 2022-02-08 | 2022-09-13 | 江苏省肿瘤医院 | Probe for pathological diagnosis of tumor and using method |
CN217219074U (en) * | 2022-05-11 | 2022-08-19 | 西安交通大学医学院第二附属医院 | Clinical sampling device of breast cancer |
CN114983489A (en) * | 2022-05-31 | 2022-09-02 | 华中科技大学同济医学院附属协和医院 | Sampling device before tumour inspection |
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