CN1155440A - Midiator for capsule in which powdered drug is filled - Google Patents

Abstract

A medicator for a capsule filled with a powdered drug, comprising: a first member adapted to receive a capsule therein; a second member, having an air supply valve structure, arranged to communicate with the first member; a third member removably attached to the first member; a drug trapping structure formed in the air stream passage to trap part of powdered drug contained in a capsule which falls down into the drug trapping structure; and a drug collecting structure formed in the air stream passage between the drug trapping structure and the air supply valve structure to collectively dam powdered drug from a capsule which falls in a direction opposite to the first member together with air when the air supply valve structure is in an intermediate state, thereby preventing powdered drug from entering the air supply valve structure.

Description

Be used to fill the capsular medicinal sprayer of powdered drug

The present invention relates to an a kind of medicinal sprayer (medicator) that is suitable for the built-in powdered drug of a capsule is sent into patient's endosome.

Usually the method for obeying powdered drug for the patient that bronchus allergic disease or asthma are arranged is by his or his nose or mouth carry out internal medicine to above-mentioned disease and handle.In addition, in this Therapeutic Method, utilize an injection of controlling oneself the built-in powdered drug of capsule to be sent into patient's nose and mouth (nostril and oral cavity).

Japanese patent application discloses No. 66382 illustration in 1991 for the first time and has used above-mentioned self-holding injection, for example by patient's nose (nostril) powdered drug is sent into the inside of patient's endosome.

In the injection that above-mentioned Japanese patent application disclosed, a pump chamber is housed in the inlet side of a draft chamber, be equipped with one in the downstream chamber of this draft chamber and hold a capsular powder shell chamber.Then, the front end in body of powder shell chamber forms a spray-hole.In addition, capsule sealing is releasably attached to the powder shell chamber.In the time of in capsule seals the front end that is installed to the powder shell chamber, in the capsule sealing, seal axially extended one long pinnacle and be used for penetrating at the intravital capsule of powder shell along capsule.And, a movable valve is installed, be used for pressure current is flowed to the powder shell chamber from pump chamber, and stop the pressure air stream opposite on the air channel in draft chamber with the pressure air flow direction.

When making a call to a hole on a capsule, the capsule of filling powdered drug is installed in the powder housing, and then, this pinnacle is threaded into a spray-hole of powder housing, from the front end of powder shell chamber the capsule sealing to be installed.This pinnacle is made in the air vent that the capsule axis direction penetrates.

Secondly, in order to take powder pharmaceutical, the capsule sealing is removed from the powder shell chamber, the front end of powder shell chamber is inserted patient's nostril, pump chamber is pressurizeed, thereby by the passage in draft chamber the air from pump chamber is led in the capsule, this air makes the medicine in capsule spray into patient's a nostril by a spray-hole.Patient alternately inserts the leading section of powder shell chamber, pressurization repeatedly on pump chamber, thus medicine is sent in the nostril, the left and right sides.On the other hand, in the dispenser operating process and when pump chamber returns to original state (pump chamber suction extraneous air), from the spray-hole outflow air of powder shell chamber, and with the medicine reverse flow.Yet movable valve stops medicine to enter pump chamber.

, require slightly time because movable valve moves to buttoned-up status from full open position, when movable valve moves to complete closed position when fixing this movable valve, medicine is to flow in the other direction.Spray repeatedly medicine be collected on the movable valve, thus movable valve can not open, and make medicine inflow pump chamber.And because the part medicine that is contained in the capsule flows into pump chamber, patient can not take needed drug dose, has reduced the effect of medicine at patient's endosome.

An object of the present invention is to provide a kind of capsular improvement medicinal sprayer that is used to fill powdered drug, it can guarantee to prevent that the part powdered drug from entering the pump chamber of a steam supply valve structure, and desired drug dose can be sent into the endosome that disease is gone into.

In order to finish above-mentioned purpose, the capsular medicinal sprayer that is used to fill powdered drug comprises: one is configured to accept described capsular first member within it; One has second member of a steam supply valve structure, and it is configured to and can be communicated with first member, and can receive capsular first member with being displaced into from the outside inhaled air of medicinal sprayer effectively; One airflow path that in described first member and described second member, forms, it can will be directed to the capsule that described first member is accepted from described steam supply valve structure air discharged; One movably is connected in the 3rd member of first member, and it can guide the outside direction of medicinal sprayer into by the injection of powdered drug that gas channel will be in capsule with the air of discharging from the steam supply valve structure; One medicine barrier structure in the interior formation of described airflow path, it can stop the part powdered drug in the described capsule that falls from capsule; An and medicine collection structure that forms in the described airflow path between medicine barrier structure and steam supply valve structure, it can work as steam supply valve be in stop effectively in the intermediateness between a full open position and the buttoned-up status with air flow along with to the mobile in the opposite direction powdered drug in described capsule in the first member side, thereby stop powdered drug to enter the steam supply valve structure.

Brief description of drawings

Fig. 1 is the drawing in side sectional elevation that is used to fill a capsular medicinal sprayer of powder medicine shape product according to the present invention's first preferred embodiment.

Fig. 2 is the outside drawing of one the 3rd member (injection channel forms member) of the medicinal sprayer represented of Fig. 1.

Fig. 3 is the amplification drawing in side sectional elevation of a capsule maintaining part of the medicinal sprayer represented among Fig. 1.

Fig. 4 is the drawing in side sectional elevation of an essential part shown in Figure 1, and expression is sprayed medicine state in the capsule with the pump portion of pressure.

The drawing in side sectional elevation of Fig. 5 on same position, seeing with Fig. 3, expression injected powder pharmaceutical mobile when the origin-location is got back to by a pump portion.

Fig. 6 is the drawing in side sectional elevation according to an essential part of air duct in second preferred embodiment of medicinal sprayer of the present invention.

Fig. 7 is the drawing in side sectional elevation of spray coyote hole one essential part in first modification of first preferred embodiment.

Fig. 8 is the drawing in side sectional elevation of medicinal sprayer one essential part in second modification of first preferred embodiment.

Fig. 9 is a drawing in side sectional elevation of medicinal sprayer one essential part in the 3rd modification of first preferred embodiment.

Implement best way of the present invention below in conjunction with the accompanying drawing introduction.So that understand the present invention better.

Fig. 1 to Fig. 5 has shown first preferred embodiment that is used to fill a capsular medicinal sprayer of a powdered drug according to the present invention.

Among Fig. 1 to Fig. 5, there is an acceptance to fill the capsular capsule holder 1 of powdered drug.

Capsule holder 1 comprises and is the columniform fixture 2 of a pair of and at a movable piece 9 of the axially movable arrangement of this fixture 2.

As shown in Figure 3, fixture 2 comprise have in Fig. 1 upward to an opening, a cylindrical shell 3.Shell 3 comprises: a major diameter housing parts 3A; The bottom 3B of this major diameter housing parts 3A; From bottom 3B continuously and a minor diameter housing parts 3C who extends downwards from bottom shell body 3B; Lower bottom part 3D in the end of minor diameter housing parts 3C; Be formed on the end one flange section 3E of the opening of diameter housing parts 3A, this flange section 3E is mainly used to stop the decline of a movable piece 9, this movable piece 9 moves at the axial inner rim along housing parts 3A of major diameter housing parts 3A, be used for locating a pump portion 15, pump portion 15 is configured to the excircle sealing fixture 2 from fixture 2, chats as the back.In addition, be formed with an air supply channel 4 of in pump portion 15, opening on the lower bottom part 3D.A link slot 5 the extending axially that is connected with pin 11 at movable piece 9.Pin 11 is used for stoping rotatablely moving of movable piece 9 relative fixed parts 2.One inner housing part 6 is placed in the shell body part 3.Inner housing part 6 comprises a housing parts 6A; The 6C of projection once that extends downwards from the bottom 6B of housing parts 6A, thus limited the program of opening of a steam supply valve 14, as described later; Its diameter is from a crocodile notch portion 6D of the open sides extension of housing parts 6A; An and 6E of hole portion who surrounds by the wall of the wall of housing 6A and bottom 6B.Inner housing part 6 links to each other by crocodile notch portion 6D with the inner periphery of the major diameter housing parts 3A of shell body 3.In addition, following projection 6C contacts with air feed valve body 14, with the degree of opening (lift variation of steam supply valve) of restriction steam supply valve 14.

One bending channel 7 is formed between shell body part 5 and the inner housing part 6, and is the part of gas channel.Bending channel 7 comprise one have a minor diameter, along the axially extended of inner housing part 6 and be formed in down first passage 7A on the excircle of projection 6C; One from the upper end of first passage 7A upward to the second channel 7B of bending, its diameter is to extend in the portion radially outward of second channel; And the excircle end from second channel 7B, upward to the third channel 7C that extends.The lower end of first passage 7A is communicated with air supply channel 4 by steam supply valve 14.

Inner housing part 6 is provided with each vent passages 8, and this each vent passages 8 is being provided on the diametric(al) on the housing parts 6, so that third channel 7C is communicated with the following medicine stop portions 29 that will narrate.

Movable piece 9 is the axial directions that movably are placed in fixture 2, and this movable piece 9 comprises housing parts 9A; Be provided with major diameter bottom 9B in the lower end of housing parts 9A, so that in the major diameter housing parts 3A of shell body 3, keep axially-moveable; An and projection 9C who in the housing 6A of inner housing part 6, extends from the center of bottom 9B.On a whole outer peripheral face of the inner circumferential surface of housing parts 9A, be processed with pin thread 9D.Along minor diameter projection 9C axially be provided with the one first pinnacle patchhole 10 that one first pinnacle 24 penetrates, and pass bottom 9B and feed housing 9A.Pin 11 excircle ends, protrude at the outward direction of housing parts 9A from housing parts 9.Pin 11 combines with the link slot 5 of fixture 2, thereby allows movable piece 9 relative fixed parts 2 to move axially, and limits the rotation of movable piece 9 relative fixed parts 2.

On the other hand, the inner circumferential side at the housing parts 9A of movable piece 9 forms a diameter side capsule hole 12 bigger slightly than capsule K (as shown in Figure 4).One side capsule hole 12 combines with other side capsule hole 21 and constitutes a capsule receiver hole 13.

In the capsule holding member 1 of first embodiment, movable piece 9 is being axially moveable along the shell body part 3 of fixture 2.In addition, when the pin thread 90 of movable piece 9 is screwed in the female thread 20A, stops the rotation of pin 11 restriction movable pieces 9 relative fixed parts 2 with rotation, thereby automatically be pulled upwardly to injection channel formation part 18.

Steam supply valve 14 with a valve body 14 is installed in the minor diameter housing parts 3C, to open or close the gas passage 4 that is formed on the fixture 2.When from pump portion 15 supply air, steam supply valve 14 is opened (pump housing arrives projection 7A down).When air suction pump portion 15, pump housing sealing, thus close air feed passage 4.

Pump portion 15 is cylindric, is to be made of elastomeric material.Pump portion 15 comprises: thick perforate part 15A, a bottom 15B and compressible (flexibility) part 15C who forms between thick perforate part 15A and bottom 15B.Thick perforate part 15A is connected on the major diameter housing parts 3A of shell body part 3 airtightly.In addition, almost all of capsule holding member 1 in addition part all be contained in the pump portion 15, thereby medicinal sprayer can be at axial miniaturization.

At the bottom of pump portion 15 15B one suction valve structure 16 is set.Suction valve structure 16 comprises: one is positioned at the suction passage 16A of the end in the core of 15B, with pump portion 15 in are communicated with; An and pump housing 16B, when an operator (patient) pressurization, compression compressible portion 15C, pump housing 16B closes, to deliver to the capsule that is held at the extraneous air of the medicinal sprayer in the pump portion 15, when compressible portion 15C when compressive state is returned to initial condition, pump housing 16B opens, with extraneous air suction pump portion 15.

The hole 10 that air supply channel 4, bending channel 7, each vent passages 8 and pinnacle are stretched into forms a gas channel 17.

Gas channel 17 is used for making from pump portion 15 air supplied and flows to the capsule K that keeps in capsule holder 1.

The movable piece 9 of capsule holding member 1 is provided with to spray and forms channel part 18.Capsule holding member 1 comprises a minor diameter 18A of the lower end that is positioned at capsule holding member 1 and is positioned at a large-diameter portion 18B of capsule holding member 1 upper end.On the upper end of large-diameter portion 18B, form and protrude a pair of left and right sides nozzle 19,19.

On small diameter portion 18A, form a screw 20 that is used for movable piece 9, and the female thread 20A that on the inner periphery of the open side of screw 20, forms the pin thread 9D that is screwed into movable piece 9.On the deep-section of screwed hole 20, form opposite side capsule hole 21, and form capsule receiving orifice 13 with a side capsule hole 12.

Spraying a pair of left and right sides of formation medicine passage 22,22 on the formation channel part 18.Each medicine passage 22 is formed on its cardinal extremity partly has a public passage, its top that roughly in the passage of U-shaped of branch passage arranged.The branch passage provides jet exit 23,23 respectively on its top.

First pinnacle, 24 usefulness, one pin is to the lower end punching of capsule K, and in fixture 2, extend, first pinnacle 24 have one be fixed on the following projection 6C of inner housing part 6 a cardinal extremity and from the hole 13 lower end protrude and form a top of prong 24A shape towards the opening in this hole.

There is prong on first pinnacle 24 on its top, when movement parts 9 was positioned at pump portion 15 places, this prong protruded from the bottom of capsule receiver hole 13.In this state, when capsule K when press being inserted capsule receiver hole 13, on capsule K, form an airflow hole H1 (as shown in Figure 4).

On the other hand, when movable piece 9 was placed on injection formation channel part 18 sides, in the top 24A retraction pin patchhole 10 on first pinnacle 24, thereby the top 24A on first pinnacle 24 pulled out from airflow hole H1.At this moment, first pinnacle 24 is positioned at pin patchhole 10, and the flow channel area that forms on pin patchhole 10 is by throttling.Therefore, pin patchhole 10 can make the air velocity of the air of self-pumping portion 15 to increase, and the increase of air velocity can make that then the medicine in the capsule K is effectively stirred.

In spraying formation channel part 18, one second pinnacle 25 is set, so that facing to first pinnacle 24.On the slide block 26 that one cardinal extremity on second pinnacle 25 is fixed on slidably and axially disposes.Stretch out so that can penetrate a caulking gum 27 on the top on second pinnacle 25, and form a prong 25A.Slide block 26 is connected to an operation panel 28 (as shown in Figure 2), and operation panel 28 is arranged on and sprays the outside that forms channel part 18, so that operate second pinnacle 25.When operation panel 28 moves with direction of arrow A shown in Figure 2, move with the direction of arrow A shown in scheming by slide plate 26 in second pinnacle 25.The top 25A on second pinnacle 25 is used for penetrating capsule K, forms the air-flow H2 that portals.

On the bottom of the bore portion 6E of inner housing part 6, be provided with one and fall medicine stop portions 29.Thin medicine stop portions 29 down is used for collecting the medicine that falls from the airflow hole H1 that is passed at capsule K by first pinnacle 24 by first pinnacle 24 when medicinal sprayer is in position from Fig. 1 to shown in Figure 5 and ground approximate vertical.Therefore, falling medicine stop portions 29 can prevent to enter steam supply valve structure 14 from the powdered drug that capsule K falls.In addition, the air of sending according to each vent passages 8 during medicine in spray offers patient with falling powdered drug that medicine stop portions 29 the collects powdered drug with capsule K.

Form a reverse flow stop portions 30 outside between housing parts 3 and the inner housing part 6.In first embodiment, reverse flow stop portions 30 comprises that an annular that is positioned on the interior diameter side of radially extending passage 7B of bending channel 7 protrudes wall part 31, it is protruding upward from the bottom 3B of shell 3, and usefulness protrusion wall part 31 stops the medicine collection space 32 that radially extends passage 7B formation.It should be noted that and between the bottom 6B that protrudes wall part 31 and inner housing part 6, form a throttling passage 33.

The reverse flow medicine is collected part 30 and is made the air circulation that comprises powdered drug with radially extending passage 7B, and with protrude wall part 31 when powdered drug with air with when injection channel spare 18 sides are mobile in the opposite direction, stop the air that comprises powdered drug, thereby collect airborne powdered drug at medicine collection space 32, so just prevented that powdered drug is bonded on the steam supply valve structure 14 and enters pump portion 15.In addition.The circulating air that 33 pairs of throttling passages flow to pump portion 15 produces a circulation resistance, thereby the reverse air flow self that flows to pump portion 15 can be suppressed, and can prevent the reverse flow of powdered drug.

On the other hand, spray during medicine with the air of discharging from pump portion 15, the medicine that will in medicine collection space 32, collect in capsule K powdered drug and the medicine that is falling in the medicine stop portions 29 supply with patient.

When with medicinal sprayer powdered drug being sent into patient's endosome, the operation of the medicinal sprayer among first embodiment is with as described below.

At first, the movable piece 9 with capsule holding member 1 is placed on the bottom protrusion of the top 24A on pump portion 15, the first pinnacles 24 towards capsule receiver hole 13.In this case, capsule K is inserted in the capsule receiver hole 13, and capsule K is pressed into capsule receiver hole 13 by patient's finger.Like this, the top 24A on first pinnacle 24 thrusts (penetrating) capsule K, thereby forms an airflow hole H1 on capsule.

Secondly, will spray formation channel part 18 and be assembled in the capsule holding member 1, screw thread 20A will be screwed into the pin thread 9D at capsule holding member 1 place.So just the movable piece 9 of capsule holding member 1 is formed channel part 18 and moves towards spraying, so that capsule receiver hole 13 in, capsule K is pressurizeed and keeps axially pressurizeing a little of keeper 1 by the screw thread that spray to form in the channel part 18.At this moment, extract from capsule K, capsule K is communicated with bending channel 7 by airflow hole H1, hole 10 and each venting channels 8 thrusting the top 24A of capsule K with first pinnacle 24 of formation airflow hole H1.

When with first pinnacle 24 when capsule K extracts, just make the medicine among the capsule K fall into inner housing 6 from airflow hole H1.Yet the medicine that falls all is collected in falling in the medicine stop portions 29 of forming in the inner housing part 6.

And, in order in capsule K, to form airflow hole H2, operation panel 28 is moved along direction A shown in arrow among Fig. 2, so just second pinnacle 25 is moved towards capsule K direction, and make the top 25A pressurized on second pinnacle 25 and thrust capsule K with formation airflow hole H2.Then, along with operation panel 28 is replied original position, the top 25A on second pinnacle 25 is extracted from capsule K.Then carry out the punch operation of capsule K, prepare powdered drug is sent into patient's endosome.

To then be described in below and go into intranarial operation after the capsule K punch operation of accepting the powdered drug in the capsule K being sent into disease.

At first, every nozzle 19 is inserted in the respective aperture in a sick nostril, and push compressible (flexibility) part 15C by the direction of arrow P as shown in Figure 4, thereby produce the air-flow of self-pumping portion 15, this air-flow acts on the air supply channel 4, thereby steam supply valve structure 14 is pressed onto down protuberance 6C, opens supply valve structure 14.Like this, compressed air flows into capsule K by air supply channel 4, bending channel 7, each gas channel 8 and hole 10 from airflow hole H1.Flow into the air agitation medicine of capsule K, form the medicine mixed with air.This medicine that is mixed with air passes through a pair of left and right sides nozzle 23 and 23, thereby pulverous medicine can be sent into simultaneously patient's nostril, the left and right sides by airflow hole H2 and a pair of left and right sides medicine passage 22,22.

On the other hand, if discharge the power on the compressible portion 15C that is applied to pump portion 15, compressible portion 15C returns to original form by the elastic force of self with the direction of arrow R, shown in the chain-dotted line of Fig. 4, thereby pump portion forms a negative pressure, open the pump housing 16B of inlet valve structure 16, air outside is sucked the pump housing 15 by air intake passage 16A.

Should note, though because the negative pressure that the pump housing 15 produces is enclosed on the air supply channel 4 valve body of supply valve structure 14, air supply channel is closed, carry out the transition in the time of buttoned-up status from full open position at steam supply valve 14, suck a spot of extraneous air from each jet expansion 23, thus the medicines of extraneous air being collected in falling medicine stop portions 29 by each vent passages 8 with flow to bending channel 7 in the opposite direction to jet expansion 23 sides.

Yet in first embodiment, the radially extension passage 7B of bending channel 7 is provided with and protrudes wall part 31.Like this, as shown in Figure 5, the powdered drug of reverse flow part can be protruded wall part 31 and be stopped, collects the medicine of reverse flow at medicine collection space 32.In addition, because throttling passage 33 is formed in the passage between the bottom 6B that protrudes wall part 31 and inner housing part 6, throttling passage 33 is acting on circulation resistance on pump part 15 circulation air.Therefore itself can suppress to flow to the reverse air flow of pump portion 15, and can prevent that powdered drug from passing through steam supply valve structure 14 reverse inflow pump portions 15.

On the other hand, when dusting the powder medicine, be collected in to fall medicine stop part 29 and be blocked in medicine collection space 32 interior powdered drug and can accompany or follow the endosome that the medicine of air in capsule K of pump portion 15 discharges supplied patient.

Because first preferred embodiment at the medicinal sprayer of the capsule K that is used for filling powdered drug, fall in the way that medicine stop part 29 is formed in the inner housing part 6 and reverse flow medicine collection unit 30 is arranged on by air flow passage 17, reverse flow medicine collection unit 30 is to be made of the protuberance 31 that has defined medicine collection space 32, the medicine that falls from capsule K can be blocked in and fall medicine stop part 29, when the compressible portion 15C of pump portion 15 gets back to original state, the medicine that flows to pump portion 15 stops with the protrusion wall portion 31 that reverse air flow is reversed stream medicine collection unit 30, thereby the reverse flow medicine is collected in medicine collection space 32.Thereby can prevent that powder is with medicine inflow pump portion 15 two stages.

Therefore, can prevent owing to from the effusive powdered drug of capsule K bonding be collected on the pump housing of steam supply valve structure 14 and cause the pump of transfer pump structure to open error, and stop powdered drug to enter pump portion 15.

In addition, owing to form throttling passage 32, it flows to the air effect air circuit resistance of pump portion 15 at reverse flow medicine collection unit 30 places, can suppress to flow to the reverse air flow of pump portion 15 itself.In this respect, can prevent that also medicine from entering pump portion.

And, because when dusting the powder medicine, the powdered drug that is collected in the powdered drug that falls medicine stop part 29 and is collected in medicine collection space 32 is accompanyed or follow the medicine of air in capsule K that pump portion 15 discharges and is supplied with the patient who contacts with jet expansion 23,23, can the dose a patient with medicine of required dosage has improved the effectiveness of medicine.

It should be noted,, can temporarily be collected in the powdered drug part of collecting in the medicine collection space 32 because medicine collection space 32 is to define by protruding wall portion 31.Even the vertical direction on the relative ground of medicinal sprayer tilts, can prevent that also collected medicine from falling into pump portion 15.Therefore operating medicinal sprayer becomes very convenient.

On the other hand, the instrument itself that capsule is punched is combined as a whole with medicinal sprayer, needn't dismantle this instrument and just can spray the medicine operation.Like this, just can save at Japanese patent application and disclose the operation that desired dress is inserted this type of instrument in 1991 No. 66382 for the first time.In addition, this instrument can not be lost, and has improved processing safety.

Fig. 6 has shown second preferred embodiment that is used to fill the capsular medicinal sprayer of powdered drug according to the present invention.

Here only narration and difference at Fig. 1 first shown embodiment in Fig. 5.

In second embodiment shown in Figure 6, protrude wall part and comprise two protrusion wall parts as described below.

That is to say that reverse flow medicine collection unit branch in a second embodiment comprises: a) an annular minor diameter protrudes wall part 42, and it protrudes towards last direction from the bottom 3B of shell 3, and be positioned at the smaller diameter side of radially extending passage 7B as shown in Figure 6; B) an annular major diameter is protruded wall part 43, it from the bottom 6B of inner housing part 6 towards under direction protrude, and be positioned at the overall diameter side of radially extending passage 7B; And c) medicine collection space 44, it stops that by protruding wall part 42 and 43 radially extending passage 7B forms.Like this, between the bottom 6B of minor diameter projection 42 and inner housing part 6, major diameter is protruded between the bottom 3B of wall part 43 and shell body part 3 and minor diameter protrudes the throttling passage 45 that formation cross section between wall part 42 and the major diameter protrusion wall part 43 is crank shape.

The total advantage with first embodiment of the advantage of second embodiment is identical.The special feature of second embodiment is: because minor diameter protrudes wall part 42 and major diameter protrusion wall part 43 is overlapping, the protrusion wall part 42 of this dual structure and 43 can be guaranteed to stop the edge and partly flow into steam supply valve structure 24 towards nozzle 23 and the mobile in the opposite direction powdered drug of 23 sides more energetically.In addition,, can increase the circulation resistance that throttling passage 44 produces, can guarantee that better containment flows to the reverse air flow of pump portion 15 owing to form the throttling passage 44 that cross section is crank shape.

Fig. 7 has shown first modified version of medicinal sprayer among first embodiment.

As shown in Figure 7, reverse flow medicine collection unit 51 can comprise that one is arranged on and radially extends in the passage 7B, protrudes wall portion 52 towards the inner circumferential side thorax that radially extends passage 7B taper protruding upward gradually, one is formed on taper protrudes taper medicine collection space 53 in the wall portion 52, and is formed on taper and protrudes throttling passage 54 between the bottom 3B of wall portion 52 and shell body 3.

Fig. 8 has shown second modified version of the medicinal sprayer of first embodiment.

As shown in Figure 8, reverse flow medicine collection unit 61 can comprise that one radially has the protrusion wall part 62 of big thickness at it, one by protruding that wall part 62 defines in case with the successive spill ring-type medicine collection space 63 of downside of the major diameter axial passage 7C of bending channel 7B, an and throttling passage 64 that between the bottom 3B that protrudes wall part 62 and shell body part 3, forms.

Fig. 9 has shown the 3rd modified version of the medicinal sprayer of first preferred embodiment.

As shown in Figure 9, the reverse flow medicine is collected part 71 can comprise a protrusion wall part 72 that upwards forms to the bottom 6B of housing parts 6 from the bottom 3B of shell body part 3, by protruding the medicine collecting region 73 that wall part 72 defines, and protruding a plurality of throttling passages 74,74 that radially form of wall part 72 ...

In each embodiment of medicinal sprayer, by a pair of left and right sides of branch medicine passage 22 and 22, and be imported into a pair of left and right sides jet expansion 23 and 23 that enters nostril, the patient left and right sides at reaction-injection moulding channel part 18, so that simultaneously powder medicine shape medicine is sent into the patient nostril.Yet the medicine passage can be single, thereby can alternately powdered drug be sent into two nostrils of patient by the single-nozzle outlet.

Though in first and second embodiment, the capsular medicinal sprayer that is used to fill powdered drug can be applicable to patient's nostril, the present invention also can be applicable to powdered drug is supplied the medicinal sprayer of disease entrance cavity.

Claims (12)

1. capsular medicinal sprayer that is used to fill powdered drug, it comprises: one can receive described capsular first member within it; One has second member of a steam supply valve structure, and it is configured to and can be communicated with first member, accepts capsular first member so that can drain into from the outside inhaled air of medicinal sprayer; One airflow path at described first member and the described second member internal shaping, it can will guide the capsule of being accepted by described first member into from described supply air valve structure air discharged; One movably is connected in the 3rd member of first member, and it just can be with the powdered drug in the described capsule being sprayed the outside direction of guiding medicinal sprayer into from supply valve structure air discharged by gas channel;

One is formed on the medicine barrier structure in the described gas channel, and it can collect part powdered drug that fall from capsule, in described capsule; And

The one medicine collection structure that between medicine barrier structure and steam supply valve structure, forms in the described gas channel, it can be when the steam supply valve structure be in a intermediateness between a full open position and the buttoned-up status, stop effectively with air flow together along with towards the mobile powdered drug in described capsule of the opposite direction of first member, thereby stop this powdered drug to enter the steam supply valve structure.

2. the capsular spray coyote hole that is used to fill powdered drug as claimed in claim 1, it is characterized in that, described medicine collection structure comprises a medicine collection space that is provided with on the described gas channel between medicine collection structure and the steam supply valve structure, and it is formed in axial bending in the bending channel that the medicine barrier structure radially forms, to second member, and radially is shaped to the steam supply valve structure.

3. the capsular medicinal sprayer that is used to fill powdered drug as claimed in claim 2 is characterized in that, extends one from described second member and protrudes wall part, shrinks medicine device collection space with the end place towards the steam supply valve structure at bending channel.

4. the capsular medicinal sprayer that is used to fill powdered drug as claimed in claim 3, it is characterized in that, described second member comprises first pinnacle at the tip passing described medicine barrier structure and extend, to poke a described capsular bottom of being accepted by described first member, and make powdered drug fall into the medicine barrier structure, with a described steam supply valve structure at the axially extended protuberance of described second member is arranged, described protuberance is as a valve seat of this supply valve structure, and one in first hole that defines buttoned-up status with form movable valve body between the valve seat of full open position.

5. the capsular medicinal sprayer that is used to fill powdered drug as claimed in claim 4, it is characterized in that, described second member comprises a pump chamber that is formed by a flexible piece, it can be to the bending of the inner space of pump chamber under a pressure effect, thereby makes the air in described pump chamber deliver to gas channel through open mode, bending channel and the medicine barrier structure of steam supply valve.

6. the capsular medicinal sprayer that is used to fill powdered drug as claimed in claim 5, it is characterized in that, described pump chamber comprises the air suction valve structure that when opening the extraneous air of medicinal sprayer is sucked pump chamber, when a power is applied to this flexible piece, this flexible piece is pressed towards the inner space of pump chamber, and under the pressure release conditions, this flexible piece is returned to its original state, and a power when being applied to this flexible piece, air suction valve structure pressurized is under pressure closed.

7. the capsular medicinal sprayer that is used to fill Powdered medicine device as claimed in claim 6, it is characterized in that, described the 3rd member comprises that at least one is from a medicine injection channel of going into interruption-forming, a described capsular top of being accepted by described first member in this porch is connected with a jet expansion, and one has the tip of extending to poke this capsular vertical second pinnacle in described the 3rd member.

8. the capsular medicinal sprayer that is used to fill powdered drug as claimed in claim 6, it is characterized in that, described the 3rd member comprises a pair of from a left and right sides injection channel of going into interruption-forming, a described capsular top of accepting by first member in this porch with can be connected with the contacted a pair of left and right sides, a patient nostril jet expansion, and one has a tip of extending to poke this capsular vertical second pinnacle in described the 3rd member.

9. the capsular medicinal sprayer that is used to fill powdered drug as claimed in claim 2, it is characterized in that, major diameter and minor diameter protrude wall portion and extend from described second member, to form the medicine collection space that cross section is an approximate crank shape at this bending channel towards an end of steam supply valve structure.

10. the capsular medicinal sprayer that is used to fill powdered drug as claimed in claim 2 is characterized in that, taper protrusion wall portion extends from second member, little by little to shrink the medicine collection space at this bending channel towards an end of steam supply valve structure.

11. the capsular medicinal sprayer that is used to fill powdered drug as claimed in claim 3 is characterized in that, major diameter protrusion wall portion extends from described second member, to form a throttling passage at this bending channel towards supply valve structure one end.

12. the capsular medicinal sprayer that is used to fill powdered drug as claimed in claim 11 is characterized in that, forms a plurality of throttling passages between bending channel and steam supply valve structure.

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