CN115487421A - Cardiac pacemaker system, cardiac pacing control method and electronic equipment - Google Patents
Cardiac pacemaker system, cardiac pacing control method and electronic equipment Download PDFInfo
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- CN115487421A CN115487421A CN202211123534.4A CN202211123534A CN115487421A CN 115487421 A CN115487421 A CN 115487421A CN 202211123534 A CN202211123534 A CN 202211123534A CN 115487421 A CN115487421 A CN 115487421A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/362—Heart stimulators
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/362—Heart stimulators
- A61N1/365—Heart stimulators controlled by a physiological parameter, e.g. heart potential
- A61N1/36507—Heart stimulators controlled by a physiological parameter, e.g. heart potential controlled by gradient or slope of the heart potential
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/372—Arrangements in connection with the implantation of stimulators
- A61N1/37211—Means for communicating with stimulators
- A61N1/37217—Means for communicating with stimulators characterised by the communication link, e.g. acoustic or tactile
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/372—Arrangements in connection with the implantation of stimulators
- A61N1/37211—Means for communicating with stimulators
- A61N1/37235—Aspects of the external programmer
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/372—Arrangements in connection with the implantation of stimulators
- A61N1/37211—Means for communicating with stimulators
- A61N1/37252—Details of algorithms or data aspects of communication system, e.g. handshaking, transmitting specific data or segmenting data
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/372—Arrangements in connection with the implantation of stimulators
- A61N1/375—Constructional arrangements, e.g. casings
- A61N1/37512—Pacemakers
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- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06F—ELECTRIC DIGITAL DATA PROCESSING
- G06F21/00—Security arrangements for protecting computers, components thereof, programs or data against unauthorised activity
- G06F21/30—Authentication, i.e. establishing the identity or authorisation of security principals
- G06F21/44—Program or device authentication
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06F—ELECTRIC DIGITAL DATA PROCESSING
- G06F21/00—Security arrangements for protecting computers, components thereof, programs or data against unauthorised activity
- G06F21/30—Authentication, i.e. establishing the identity or authorisation of security principals
- G06F21/45—Structures or tools for the administration of authentication
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H40/00—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices
- G16H40/60—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
- G16H40/67—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
Abstract
The invention discloses a cardiac pacemaker system, a method for controlling cardiac pacing and an electronic device, wherein the cardiac pacemaker system comprises an external controller and an internal pacemaker, wherein a first authentication unit is arranged in the internal pacemaker, a second authentication unit is arranged in the external controller, and the first authentication unit is in communication connection with the second authentication unit; the internal pacemaker is used for acquiring the electrocardio information of the heart; the external controller is in communication connection with the internal pacemaker, receives the electrocardio information sent by the internal pacemaker and sends the received control instruction to the internal pacemaker. In addition, the invention also provides a method for controlling cardiac pacing. The technical scheme provided by the invention has the capabilities of bidirectional authentication and real-time electrocardio monitoring, and simultaneously has the functions of cloud connection and remote monitoring and diagnosis and treatment.
Description
Technical Field
The invention relates to the technical field of medical electronic instruments, in particular to a cardiac pacemaker system, a method for controlling cardiac pacing and electronic equipment.
Background
Cardiac pacemakers are classified into temporary cardiac pacemakers and permanent cardiac pacemakers. For a permanent cardiac pacemaker, the permanent cardiac pacemaker can work only by depending on the power supply of an internal battery, the permanent cardiac pacemaker can generally work for 5-10 years according to the capacity of the internal battery, and after the energy of the battery is exhausted, the permanent cardiac pacemaker needs to be replaced by a secondary operation, so that a large infection risk exists. For a temporary cardiac pacemaker, after the use, a cardiac pacing lead is usually required to be removed, and epicardial tear or even myocardial perforation may be caused in the process of removing the cardiac pacing lead. For a micro cardiac pacemaker, the micro cardiac pacemaker can be implanted through arterial blood vessel minimally invasive, but only is a single-cavity pacemaker, and only can treat slow arrhythmia, and pacemaker syndrome is easy to cause, and heart failure is aggravated;
in addition, working parameters such as pulse interval time, pulse frequency and pulse intensity during the operation of the artificial cardiac pacemaker must be set before installation, but the parameter setting needs to be changed along with the change of the age, the illness state and the like of a patient, and the artificial cardiac pacemaker can be taken out only in an operation mode to be set again, so that not only can secondary physical injury be brought to the patient, but also the safety is not high.
Disclosure of Invention
The invention provides a cardiac pacemaker system, a method for controlling cardiac pacing and an electronic device, which aim to solve part or all of the technical problems in the prior art.
In order to achieve the above object, the present invention provides the following technical solutions:
in a first aspect, the present invention provides a cardiac pacemaker system, including an external controller and an internal pacemaker, wherein the internal pacemaker is provided with a first authentication unit, the external controller is provided with a second authentication unit, and the first authentication unit is in communication connection with the second authentication unit;
the internal pacemaker is used for acquiring the electrocardio information of the heart;
the external controller is in communication connection with the internal pacemaker, receives the electrocardio information sent by the internal pacemaker and sends the received control instruction to the internal pacemaker.
In one possible implementation manner, the system further includes a processor, where the processor includes an authentication unit, and the authentication unit is connected to the second authentication unit in a communication manner;
and the processor is in communication connection with the external controller, receives the electrocardio information sent by the external controller and sends a control command to the external controller.
In one possible implementation manner, the processor is a cloud server or an intelligent terminal.
In one possible implementation manner, the processor includes a cloud server and an intelligent terminal, the authentication unit includes a third authentication unit and a fourth authentication unit, the third authentication unit is built in the cloud server, the fourth authentication unit is built in the intelligent terminal, and the third authentication unit is in communication connection with the fourth authentication unit;
the cloud server is in communication connection with the external controller and the intelligent terminal, receives the electrocardio information sent by the external controller, and sends heart risk information to the intelligent terminal;
and the intelligent terminal is in communication connection with the external controller, receives the heart risk information and sends a control command to the external controller.
In one possible implementation, the in-vivo pacemaker includes a first antenna, and the ex-vivo controller includes a second antenna;
the external controller provides electric energy to the first antenna by means of electromagnetic induction coupling by using the second antenna, and the first antenna is used for supplying power to the internal pacemaker.
In one possible implementation, the first antenna is made of a magnesium-calcium alloy.
In one possible implementation, a replaceable first biological protection film is arranged outside the first antenna, and the first biological protection film is replaced according to the service life requirement of the cardiac pacemaker.
In one possible implementation, the first biological protective film is made of poly (lactic-co-glycolic acid), polyethylene terephthalate, polyester fiber, or polyetheretherketone.
In one possible implementation, the internal pacemaker further comprises an electrode, wherein the electrode is connected with the endocardium or the surface of the cardiac muscle, and the pacing is completed by stimulating the cardiac muscle through the current.
In one possible implementation, the in vivo pacemaker further comprises a pacing lead, a pacing lead connector and a control chip;
the pacing lead is connected with the electrode and used for receiving the electrocardio information;
the control chip is connected with the pacing lead connector through the pacing lead and used for receiving the electrocardio information.
In one possible implementation mode, a replaceable second biological protection film is arranged outside the pacing lead, and the second biological protection film is replaced according to the service life requirement of the cardiac pacemaker.
In one possible implementation, the second bio-protective film is made of poly (lactic-co-glycolic acid), ethylene terephthalate, polyester fiber, or polyetheretherketone.
In one possible implementation, the pacing lead connector is 4 in total.
In one possible implementation, the electrode is made of a magnesium-calcium alloy material or a titanium alloy material.
In a second aspect, the present invention provides a method of controlling cardiac pacing, the method comprising the steps of:
an internal pacemaker acquires electrocardiogram information of a heart;
authentication is carried out between the internal pacemaker and the external controller;
and after the authentication and the authentication are passed, the external controller receives the electrocardio information sent by the internal pacemaker and sends the received control instruction to the internal pacemaker so as to control the cardiac pacing.
In one possible implementation, the authentication process between the in-vivo pacemaker and the in-vitro controller includes:
the in-vivo controller creates a device and sends a key and a password of the device to the in-vivo pacemaker;
the internal pacemaker performs pre-configuration according to the received key and the password, and returns pre-configured login information to the external controller;
and the external controller performs authentication according to the returned login information.
In one possible implementation, the method further includes:
authentication and authentication are carried out between the processor and the external controller;
and after the authentication passes, the processor receives the electrocardio information sent by the external controller and sends a control instruction to the external controller.
In one possible implementation manner, the processor is a cloud server or an intelligent terminal.
In one possible implementation, TLS handshake is performed between the processor and the external controller through an X509 certificate to perform authentication. In one possible implementation, the method further includes: the processor comprises a cloud server and an intelligent terminal, authentication and certification are carried out between the processor and the external controller, after the authentication and certification are passed, the processor receives the electrocardio information sent by the external controller and sends a control command to the external controller, and the method comprises the following steps:
the cloud server respectively performs authentication with the external controller and the intelligent terminal;
after the authentication and the certification are passed, the cloud server receives the electrocardio information sent by the external controller and sends heart risk information to the intelligent terminal;
authentication and certification are carried out between the external controller and the intelligent terminal;
and after the authentication passes, the intelligent terminal receives the heart risk information and sends a control command to the in-vitro controller.
In one possible implementation manner, the authentication process performed between the intelligent terminal and the cloud server includes:
the intelligent terminal sends the account and the password to the cloud server;
if the account exists in a database of the cloud server, the cloud server compares an SHA256 value of the password with a password field value in the database to determine whether the value is consistent;
if the two session objects are consistent, the cloud server creates a session object, and transmits the session _ id to the browser by using the setCookie;
if the browser confirms that the setCookie field exists, the intelligent terminal sends an http request carrying Cookie s _ id to the cloud server;
and the cloud server receives and confirms the http request, and if the http request is confirmed to pass, the intelligent terminal information is obtained.
In a third aspect, the present invention provides an electronic device, which includes a processor, a communication interface, a memory and a communication bus, wherein the processor, the communication interface and the memory complete mutual communication through the communication bus;
a memory for storing a computer program;
a processor for implementing the method according to any of the embodiments of the second aspect when executing a program stored in the memory.
In a fourth aspect, the invention provides a computer-readable storage medium having stored thereon a computer program which, when executed by a processor, performs a method as in any one of the embodiments of the second aspect.
Compared with the prior art, the technical scheme provided by the embodiment of the invention has the following advantages:
the cardiac pacemaker system provided by the embodiment of the invention comprises an in-vitro controller and an in-vivo pacemaker, wherein a first authentication unit is arranged in the in-vivo pacemaker, a second authentication unit is arranged in the in-vitro controller, and the first authentication unit is in communication connection with the second authentication unit; the internal pacemaker is used for acquiring the electrocardio information of the heart; the external controller is in communication connection with the internal pacemaker, receives the electrocardio information sent by the internal pacemaker and sends a received control instruction to the internal pacemaker. The system provided by the invention has the capabilities of bidirectional authentication and real-time electrocardio monitoring, and simultaneously has the functions of cloud connection and remote monitoring and diagnosis and treatment.
Drawings
Fig. 1 is a schematic structural diagram of a cardiac pacemaker system according to an embodiment of the present invention;
fig. 2 is a second schematic structural diagram of a cardiac pacemaker system according to an embodiment of the present invention;
FIG. 3 is a third schematic structural diagram of a cardiac pacemaker system according to an embodiment of the present invention;
fig. 4 is a schematic diagram of a top view of an internal pacemaker according to an embodiment of the present invention;
FIG. 5 is a schematic diagram of a side view of an in vivo pacemaker according to an embodiment of the present invention;
FIG. 6 is a flowchart illustrating a method for controlling cardiac pacing according to an embodiment of the present invention;
FIG. 7 is a schematic diagram of an authentication process between an in vitro controller and an in vivo pacemaker;
FIG. 8 is a second flowchart of a method for controlling cardiac pacing according to an embodiment of the present invention;
FIG. 9 is a diagram illustrating an authentication process between an external controller and a processor;
fig. 10 is a third flowchart illustrating a method for controlling cardiac pacing according to an embodiment of the present invention;
fig. 11 is a schematic diagram illustrating an authentication process between the smart terminal and the cloud server;
fig. 12 is a schematic structural diagram of an electronic device according to an embodiment of the present invention.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are some, but not all embodiments of the present invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
For the convenience of understanding of the embodiments of the present invention, the following description will be further explained with reference to specific embodiments, which are not to be construed as limiting the embodiments of the present invention.
It is noted that, in this document, relational terms such as "first" and "second," and the like, may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus. Without further limitation, an element defined by the phrases "comprising a component of' 8230; \8230;" does not exclude the presence of additional identical elements in the process, method, article, or apparatus that comprises the element.
In the present invention, "in one example" is used to mean "serving as an example, instance, or illustration. Any embodiment described herein as "in one example" is not necessarily to be construed as preferred or advantageous over other embodiments. The following description is presented to enable any person skilled in the art to make and use the invention. In the following description, details are set forth for the purpose of explanation. It will be apparent to one of ordinary skill in the art that the present invention may be practiced without these specific details. In other instances, well-known structures and processes are not shown in detail to avoid obscuring the description of the invention with unnecessary detail. Thus, the present invention is not intended to be limited to the embodiments shown, but is to be accorded the widest scope consistent with the principles and features disclosed herein.
To solve the technical problems mentioned in the background art, an embodiment of the present invention provides a cardiac pacemaker system, specifically referring to fig. 1, where fig. 1 is one of schematic structural diagrams of a cardiac pacemaker system provided by the present invention, and as shown in fig. 1, the cardiac pacemaker system includes: the pacemaker comprises an internal pacemaker 11 and an external controller 12, wherein a first authentication unit 111 is arranged in the internal pacemaker, a second authentication unit 121 is arranged in the external controller, and the first authentication unit 111 is in communication connection with the second authentication unit 121;
the internal pacemaker 11 is used for acquiring the electrocardio information of the heart;
the external controller 12 is in communication connection with the internal pacemaker 11, receives the electrocardiographic information sent by the internal pacemaker 11, and sends a received control instruction to the internal pacemaker 11.
In an example, as shown in fig. 2, fig. 2 is a second schematic structural diagram of a cardiac pacemaker system according to the present invention, as shown in fig. 2, the system further includes a processor 13, where the processor 13 includes an authentication unit 131, and the authentication unit 131 is communicatively connected to the second authentication unit 121;
the processor 13 is in communication connection with the external controller 12, receives the electrocardiographic information sent by the external controller 12, and sends a control instruction to the external controller 12.
In one possible embodiment, the processor 13 is a cloud server or a smart terminal. It should be noted that, when the processor is an intelligent terminal, the processor may include one intelligent terminal, or may include a first intelligent terminal and a second intelligent terminal, and if the processor includes both the first intelligent terminal and the second intelligent terminal, one of them is used by the medical staff, and the other is used by the wearer of the cardiac pacemaker. No matter the intelligent terminals are provided with the authentication units, the authentication units are communicated with other structures.
In another example, as shown in fig. 3, fig. 3 is a third schematic structural diagram of a cardiac pacemaker system provided by the present invention, as shown in fig. 3, the processor 13 includes a cloud server 14 and an intelligent terminal 15, the authentication unit 131 includes a third authentication unit 141 and a fourth authentication unit 151, the third authentication unit 141 is embedded in the cloud server 14, the fourth authentication unit 151 is embedded in the intelligent terminal 15, and the third authentication unit 141 is in communication connection with the fourth authentication unit 151;
the cloud server 14 is in communication connection with the external controller 12 and the intelligent terminal 15, receives the electrocardiographic information sent by the external controller 12, and sends heart risk information to the intelligent terminal 15;
the intelligent terminal 15 is in communication connection with the external controller 12, receives the cardiac risk information, and sends a control instruction to the external controller 12.
As can be seen from the above description, the in-vitro controller 12 has a function of periodically sending cardiac electrical information of the heart to the cloud server 14 and the intelligent terminal 15, that is, a function of sending cardiac electrical monitoring information, and has a capability of receiving control commands, such as cardiac pacing commands and configuration parameters, from the cloud server 14 and the intelligent terminal 15.
In addition, the cloud server 14 may receive the electrocardiographic information sent by the external controller 12, perform online real-time risk early warning, and actively push the identified cardiac risk information to the external controller 12 and the intelligent terminal 15, including the information system of the hospital/doctor bound by the user.
The intelligent terminal 15 can actively/passively acquire real-time electrocardiograph monitoring and historical monitoring information of a target patient, and can actively implement cardiac pacing or set a cardiac pacing strategy according to the electrocardiograph monitoring information.
The cardiac pacemaker system provided by the invention has the capabilities of bidirectional authentication and real-time electrocardiogram monitoring, and simultaneously has the functions of cloud connection and remote monitoring and diagnosis and treatment.
In an example, the present invention further provides a structural schematic diagram of an internal pacemaker, which is specifically shown in fig. 4 and 5, where fig. 4 is a schematic diagram of a top-view structure of the internal pacemaker provided in the embodiment of the present invention, and fig. 5 is a schematic diagram of a side-view structure of the internal pacemaker provided in the embodiment of the present invention.
As shown in fig. 4, the internal pacemaker includes a first antenna 1 and the external controller includes a second antenna (not labeled). The external controller 12 utilizes the second antenna to provide electric energy for the first antenna 1 in an electromagnetic induction coupling mode, and the first antenna 1 is used for supplying power for the internal pacemaker 11.
Specifically, the external controller 12 has the capability of wirelessly powering and communicating with the internal cardiac pacemaker 11, and its radio frequency range should be 2MHz to 50MHz, taking into account the attenuation of electromagnetic fields. Considering electromagnetic compatibility and power consumption of the cardiac pacemaker 11 in vivo, the radio frequency power should range from 50mW to 1000mW.
In addition, considering conditions of radiation safety, interference resistance, patient comfort and the like, the shape of the first antenna 1 can adopt a circular, square or three-dimensional structure, and the equivalent sectional area is estimated by adopting the following engineering formula:
S≈H 2 /(25*P)
wherein S is the equivalent cross-sectional area (in mm) of the first antenna 1 2 ) H is the distance (in mm) of the first antenna 1 from the body surface, and P is the radio frequency power (in W) of the extracorporeal controller 13.
In order to enable the first antenna 1 to have controllable degradation capability in a human body, the first antenna 4 is made of a magnesium-calcium alloy material, and the complete degradation time is adjusted by controlling the proportion of magnesium and calcium elements in the alloy. The complete degradable time of the first antenna 1 is controlled to be about 3 months, and the impedance of the first antenna 1 is controlled to be within the range of 50 omega +/-0.1 omega.
In order to protect the structure and the circuit of the pacemaker 11 in the body from being corroded by biological environment, a first biological protective film 2 is arranged outside the first antenna 1, the first biological protective film 2 is made of polylactic acid-glycolic acid, ethylene terephthalate, polyester fiber or polyether ether ketone, and the pacemaker is nontoxic and harmless to organisms before and after degradation, good in flexibility and comfortable in human body feeling. Specifically, when the method is applied to a temporary cardiac pacemaker scene, a polylactic acid-glycolic acid material is generally selected, the degradation time is controlled by controlling parameters such as the thickness of a protective film, the general thickness range is 10 um-1 mm, and the complete degradation time is generally 1 week-3 months. When applied to permanent cardiac pacemakers, materials such as polyethylene terephthalate or polyester fibers or polyetheretherketone are typically used. The cardiac pacemaker provided by the invention is convenient to use because the first biological protection film arranged outside the first antenna is replaceable and is replaced according to the service life requirement of the cardiac pacemaker, for example, when the permanent cardiac pacemaker needs to be used, the first biological protection film made of the material of ethylene terephthalate, polyester fiber or polyether ether ketone can be selected, and when the temporary cardiac pacemaker needs to be used, the first biological protection film made of the material of ethylene terephthalate, polyester fiber or polyether ether ketone is directly replaced by the first biological protection film made of the material of poly (lactic-glycolic acid), in other words, the first biological protection film can be replaced at any time, and in the operation process, the first biological protection film made of the corresponding material is directly selected to be arranged outside the first antenna according to the service life requirement of the cardiac pacemaker needed by a user.
In one example, the internal pacemaker 11 includes a base 3 that supports the electrical circuit, and has strength and flexibility. Specifically, the substrate 3 is made of hydrophilic polyurethane, the thickness is 20 um-100 um, and a required integrated circuit is realized on the substrate through a semiconductor sputtering process.
In one example, the internal pacemaker 11 further includes an electrode 4, the electrode 4 is connected with the surface of the endocardium or the myocardium to form an electric circuit with the heart, and the current stimulates the myocardium to complete the pacing. In different cardiac pacemakers, the material selection of the electrode 4 is different, in a temporary cardiac pacemaker, the electrode 4 is made of degradable magnesium-calcium alloy material, and in a permanent cardiac pacemaker, non-degradable titanium alloy is selected.
In one example, the internal pacemaker further comprises a pacing lead 5, a pacing lead connector 6 and a control chip 7, wherein the pacing lead 5 is connected with the electrode 4 and used for receiving electrocardio information; the control chip 7 is connected with the pacing lead connector 6 through the pacing lead 4 and is used for receiving the electrocardio information.
The control chip 7 is generally manufactured on the substrate through a thin film integrated circuit process, has a thickness of less than 50um, and has the capabilities of rectification, authentication, communication control, pulse control and electrocardio monitoring. Only authenticated triggered cardiac pacing pulses are allowed.
In order to protect the pacing lead 5, a second biological protection film 8 is arranged outside the pacing lead 5, and the second biological protection film 8 is made of polylactic-glycolic acid, ethylene terephthalate, polyester fiber or polyether ether ketone. Note that the second bio-protective film 8 is made of the same material as the first bio-protective film 2. Meanwhile, in order to make the cardiac pacemaker convenient to use, like the first biological protective film, the second biological protective film is replaceable, and is replaced according to the service life requirement of the cardiac pacemaker, for example, when the permanent cardiac pacemaker needs to be used, the second biological protective film made of ethylene terephthalate or polyester fiber or polyether ether ketone material can be selected, and when the temporary cardiac pacemaker needs to be used, the second biological protective film made of ethylene terephthalate or polyester fiber or polyether ether ketone material is directly replaced by the second biological protective film made of poly (lactic-glycolic acid) material. In other words, the second biological protection film can be replaced at any time, and the second biological protection film made of the corresponding material is directly selected to be arranged outside the pacing lead according to the age requirement of the cardiac pacemaker required by the user in the operation process.
The pacing lead 5 is connected with the electrode 4 and the main body of the internal cardiac pacemaker 11 and transmits pacing current and electrocardio monitoring signals. The selection of the pacing lead 5 material needs to be matched with the selection of the electrode 4 material, in the application scene of the temporary cardiac pacemaker, the pacing lead material should be made of a magnesium-calcium alloy material, and in the application scene of the permanent cardiac pacemaker, the pacing lead material should be made of a titanium alloy material. Therefore, as a temporary cardiac pacemaker, a patient can be discharged after a surgery without waiting for the removal of a pacing lead, and can still be monitored healthily within a certain time after the discharge.
The alloy ratio of the pacing lead wire 4 is the same as that of the first antenna 1, but it should be composed of a plurality of finer alloy wires, the number of the wires is not less than 10, and the total diameter is not more than 1mm.
As can be seen from the above description, the degradable materials are used for the components of the internal pacemaker in the invention, so that the invention has the capability of switching the temporary pacemaker and the permanent pacemaker by replacing the biological protective film and the pacing leads and electrodes.
In the invention, preferably, 4 pacing lead connectors 6 are provided, so that the internal pacemaker has the dual-chamber pacing capability, the atrioventricular conduction block problem can be solved, and the left and right atrioventricular synchronous pacing is realized. In the practical application process, 2 or 4 pacing lead wire connectors 6 can be connected according to the autonomic selection of single chamber pacing or two-chamber pacing's demand to the doctor, when carrying out single chamber pacing, select to connect 2 pacing lead wire connectors 6, and remaining 2 can seal the processing.
The embodiment of the invention provides a cardiac pacemaker system, which comprises an in-vitro controller and an in-vivo pacemaker, wherein a first authentication unit is arranged in the in-vivo pacemaker, a second authentication unit is arranged in the in-vitro controller, and the first authentication unit is in communication connection with the second authentication unit; the internal pacemaker is used for acquiring the electrocardio information of the heart; the external controller is in communication connection with the internal pacemaker, receives the electrocardio information sent by the internal pacemaker and sends the received control instruction to the internal pacemaker. The system provided by the invention has the capability of monitoring and analyzing the health state of the patient in real time through the cloud server, so that the health management of the patient after healing is greatly improved, and the life and health level of the patient are improved.
In the above, for the embodiment of the cardiac pacemaker system provided by the present invention, an embodiment of the method for controlling cardiac pacing provided by the present invention is described below, and specifically refer to the following.
Fig. 6 is a schematic flow chart of a method for controlling cardiac pacing according to an embodiment of the present invention, where the method for controlling cardiac pacing is applied to the cardiac pacemaker system in the above embodiment, as shown in fig. 6, the method includes the following steps:
And step 120, authentication is carried out between the internal pacemaker and the external controller.
And step 130, after the authentication passes, the external controller receives the electrocardio information sent by the internal pacemaker and sends the received control instruction to the internal pacemaker so as to control the cardiac pacing.
The authentication and certification process between the external controller and the internal pacemaker is briefly described below, and specifically, as shown in fig. 7, the authentication and certification process between the external controller and the internal pacemaker is as follows: the external controller creates equipment and sends the key and the password to the internal pacemaker, the internal pacemaker performs pre-configuration according to the received key and the password and then returns login information of a triple to the external controller, the external controller performs verification according to the login information, if the verification is passed, the internal pacemaker sends related data to the external controller, and the external controller sends related instructions to the internal pacemaker to execute according to the received related data.
In an example, fig. 8 is a second flowchart illustrating a method for controlling cardiac pacing according to an embodiment of the present invention, and as shown in fig. 8, the method for controlling cardiac pacing further includes:
and step 210, performing authentication between the processor and the external controller.
And step 220, after the authentication passes, the processor receives the electrocardio information sent by the external controller and sends a control instruction to the external controller.
In one possible implementation, the processor is a cloud server or an intelligent terminal. The authentication process between the external controller and the processor is briefly described below, and as shown in fig. 9, the authentication process between the external controller and the processor is as follows: the processor and the external controller perform TLS handshake through an X509 certificate to perform mutual authentication, the processor verifies the IoT HuB, the external controller verifies the device, the processor transmits data to the external controller, and the external controller transmits a configuration signal or a control signal to the processor.
In one example, the processor includes a cloud server and a smart terminal. Fig. 10 is a third schematic flow chart of a method for controlling cardiac pacing according to an embodiment of the present invention, as shown in fig. 10, where authentication and verification are performed between the processor and an external controller, and after the authentication and verification are passed, the processor receives the electrocardiographic information sent by the external controller and sends a control instruction to the external controller, where the method includes:
step 310, the cloud server performs authentication with the external controller and the intelligent terminal respectively;
and step 340, after the authentication passes, the intelligent terminal receives the heart risk information and sends a control instruction to the in-vitro controller.
The authentication process between the smart terminal and the cloud server is briefly described below, and as shown in fig. 11, the authentication process between the smart terminal and the cloud server is as follows: when a user accesses an external controller for the first time through an intelligent terminal, the intelligent terminal transmits an account and a password of the user to a cloud server, the cloud server detects whether the account exists in a database, if so, the SHA256 value of the password of the account is compared with a password field value in the database, if so, verification is passed, then the cloud server creates a session object, and transmits the session _ id to a browser through a session Cookie, the browser confirms whether the session Cookie field exists, if so, the intelligent terminal logs in successfully, sends an http request to the cloud server and carries the Cookie s _ id, the cloud server receives and confirms the request, and if so, the intelligent terminal information of the user is obtained, and transmits an in-vivo pacemaker list corresponding to the user and related information of an in-vivo pacemaker to the intelligent terminal. The account and the password of the user in fig. 11 are merely examples, and are not limited herein.
According to the method for controlling cardiac pacing provided by the embodiment of the invention, an internal pacemaker acquires cardiac electrical information of a heart; authentication and authentication are carried out between the internal pacemaker and the external controller; and after the authentication passes, the external controller receives the electrocardio information sent by the internal pacemaker and sends the received control instruction to the internal pacemaker for controlling the cardiac pacing. By the method, bidirectional authentication and real-time electrocardio monitoring can be realized, and cloud connection and remote monitoring and diagnosis and treatment can be realized.
As shown in fig. 12, an embodiment of the present invention provides an electronic device, which includes a processor 111, a communication interface 112, a memory 113, and a communication bus 114, where the processor 111, the communication interface 112, and the memory 113 complete mutual communication through the communication bus 114.
A memory 113 for storing a computer program;
in one embodiment of the present invention, processor 111, when executing the program stored in memory 113, implements the method for controlling cardiac pacing as provided by the foregoing method embodiments.
Embodiments of the present invention also provide a computer-readable storage medium having stored thereon a computer program, which, when executed by a processor, implements a method of controlling cardiac pacing as provided in the aforementioned method embodiments.
Those of skill would further appreciate that the various illustrative components and algorithm steps described in connection with the embodiments disclosed herein may be implemented as electronic hardware, computer software, or combinations of both, and that the various illustrative components and steps have been described above generally in terms of their functionality in order to clearly illustrate this interchangeability of hardware and software. Whether such functionality is implemented as hardware or software depends upon the particular application and design constraints imposed on the implementation. Skilled artisans may implement the described functionality in varying ways for each particular application, but such implementation decisions should not be interpreted as causing a departure from the scope of the present invention.
The steps of a method or algorithm described in connection with the embodiments disclosed herein may be embodied in hardware, a software module executed by a processor, or a combination of the two. A software module may reside in Random Access Memory (RAM), memory, read Only Memory (ROM), electrically programmable ROM, electrically erasable programmable ROM, registers, hard disk, a removable disk, a CD-ROM, or any other form of storage medium known in the art.
The foregoing are merely exemplary embodiments of the present invention, which enable those skilled in the art to understand or practice the present invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the generic principles defined herein may be applied to other embodiments without departing from the spirit or scope of the invention. Thus, the present invention is not intended to be limited to the embodiments shown herein but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.
Claims (23)
1. A cardiac pacemaker system is characterized by comprising an in-vitro controller and an in-vivo pacemaker, wherein a first authentication unit is arranged in the in-vivo pacemaker, a second authentication unit is arranged in the in-vitro controller, and the first authentication unit is in communication connection with the second authentication unit;
the internal pacemaker is used for acquiring the electrocardio information of the heart;
the external controller is in communication connection with the internal pacemaker, receives the electrocardio information sent by the internal pacemaker and sends the received control instruction to the internal pacemaker.
2. The system of claim 1, further comprising a processor, wherein the processor comprises an authentication unit communicatively coupled to the second authentication unit;
and the processor is in communication connection with the external controller, receives the electrocardio information sent by the external controller and sends a control command to the external controller.
3. The system of claim 2, wherein the processor is a cloud server or a smart terminal.
4. The system according to claim 2, wherein the processor comprises a cloud server and an intelligent terminal, the authentication unit comprises a third authentication unit and a fourth authentication unit, the third authentication unit is arranged in the cloud server, the fourth authentication unit is arranged in the intelligent terminal, and the third authentication unit is in communication connection with the fourth authentication unit;
the cloud server is in communication connection with the external controller and the intelligent terminal, receives the electrocardio information sent by the external controller, and sends heart risk information to the intelligent terminal;
and the intelligent terminal is in communication connection with the external controller, receives the heart risk information and sends a control instruction to the external controller.
5. The system of claims 1-4, wherein the in-vivo pacemaker includes a first antenna and the ex-vivo controller includes a second antenna;
the external controller provides electric energy to the first antenna by means of electromagnetic induction coupling by using the second antenna, and the first antenna is used for supplying power to the internal pacemaker.
6. The system of claim 5, wherein the first antenna is made of magnesium calcium alloy.
7. The system of claim 5, wherein the first antenna is externally provided with a replaceable first bio-protective membrane, and the first bio-protective membrane is replaced according to the service life requirement of the cardiac pacemaker.
8. The system of claim 7, wherein the first bio-protective film is made of poly (lactic-co-glycolic acid), ethylene terephthalate, polyester fiber, or polyetheretherketone.
9. The system of claims 1-4, wherein the internal pacemaker further comprises electrodes connected to the endocardium or myocardium surface for stimulating the myocardium by electrical current to complete pacing.
10. The system of claim 9, wherein the in vivo pacemaker further comprises a pacing lead, a pacing lead connector and a control chip;
the pacing lead is connected with the electrode and used for receiving the electrocardio information;
the control chip is connected with the pacing lead connector through the pacing lead and used for receiving the electrocardio information.
11. The system of claim 10, wherein the pacing lead is externally provided with a replaceable second bio-protective membrane, the second bio-protective membrane being replaceable according to the lifetime requirements of the cardiac pacemaker.
12. The system of claim 11, wherein the second bio-protective membrane is made of poly (lactic-co-glycolic acid), ethylene terephthalate, polyester fiber, or polyetheretherketone.
13. The system of claim 10, wherein the pacing lead connector is 4 in number.
14. The system of claim 9, wherein the electrode is made of a magnesium calcium alloy material or a titanium alloy material.
15. A method of controlling cardiac pacing, the method comprising the steps of:
an internal pacemaker acquires electrocardiogram information of a heart;
authentication is carried out between the internal pacemaker and the external controller;
and after the authentication passes, the external controller receives the electrocardio information sent by the internal pacemaker and sends the received control instruction to the internal pacemaker for controlling the cardiac pacing.
16. The method of claim 15, wherein performing an authentication process between the internal pacemaker and the external controller comprises:
the in-vivo controller creates a device and sends a key and a password of the device to the in-vivo pacemaker;
the internal pacemaker performs pre-configuration according to the received key and the password, and returns pre-configured login information to the external controller;
and the external controller performs authentication according to the returned login information.
17. The method of claim 15, further comprising:
authentication and authentication are carried out between the processor and the external controller;
and after the authentication passes, the processor receives the electrocardio information sent by the external controller and sends a control instruction to the external controller.
18. The method of claim 17, wherein the processor is a cloud server or a smart terminal.
19. A method as claimed in claim 17 or 18, wherein a TLS handshake is performed between the processor and the external controller via an X509 certificate for authentication.
20. The method of claim 17, further comprising: the processor comprises a cloud server and an intelligent terminal, authentication and certification are carried out between the processor and the external controller, after the authentication and certification is passed, the processor receives the electrocardio information sent by the external controller and sends a control instruction to the external controller, and the method comprises the following steps:
the cloud server respectively performs authentication certification with the external controller and the intelligent terminal;
after the authentication and the certification are passed, the cloud server receives the electrocardio information sent by the external controller and sends heart risk information to the intelligent terminal;
authentication and authentication are carried out between the external controller and the intelligent terminal;
and after the authentication passes, the intelligent terminal receives the heart risk information and sends a control command to the in-vitro controller.
21. The method according to claim 20, wherein an authentication process is performed between the smart terminal and the cloud server, and the authentication process includes:
the intelligent terminal sends the account and the password to the cloud server;
if the account exists in a database of the cloud server, the cloud server compares an SHA256 value of the password with a password field value in the database to determine whether the value is consistent;
if the two session objects are consistent, the cloud server creates a session object, and transmits the session _ id to the browser by using the setCookie;
if the browser confirms that the setCookie field exists, the intelligent terminal sends an http request carrying Cookie s _ id to the cloud server;
and the cloud server receives and confirms the http request, and acquires the intelligent terminal information if the http request is confirmed to pass.
22. An electronic device is characterized by comprising a processor, a communication interface, a memory and a communication bus, wherein the processor and the communication interface are used for realizing mutual communication by the memory through the communication bus;
a memory for storing a computer program;
a processor for implementing the method of any one of claims 15 to 21 when executing a program stored in a memory.
23. A computer-readable storage medium, on which a computer program is stored, which, when being executed by a processor, carries out the method according to any one of claims 15-21.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211123534.4A CN115487421A (en) | 2022-09-15 | 2022-09-15 | Cardiac pacemaker system, cardiac pacing control method and electronic equipment |
| PCT/CN2023/077208 WO2024055511A1 (en) | 2022-09-15 | 2023-02-20 | Cardiac pacemaker system, method for controlling cardiac pacing, and electronic device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN202211123534.4A CN115487421A (en) | 2022-09-15 | 2022-09-15 | Cardiac pacemaker system, cardiac pacing control method and electronic equipment |
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| CN115487421A true CN115487421A (en) | 2022-12-20 |
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| CN202211123534.4A Pending CN115487421A (en) | 2022-09-15 | 2022-09-15 | Cardiac pacemaker system, cardiac pacing control method and electronic equipment |
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| CN (1) | CN115487421A (en) |
| WO (1) | WO2024055511A1 (en) |
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| WO2024055511A1 (en) * | 2022-09-15 | 2024-03-21 | 首都医科大学附属北京安贞医院 | Cardiac pacemaker system, method for controlling cardiac pacing, and electronic device |
Family Cites Families (13)
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| US8838244B2 (en) * | 2006-06-02 | 2014-09-16 | Semiconductor Energy Laboratory Co., Ltd. | Cardiac pacemaker device with circuits for monitoring residual capacity of battery |
| CN101352596B (en) * | 2008-09-19 | 2011-06-29 | 清华大学 | In vitro power supply type implantation medical instrument |
| CN102500057B (en) * | 2011-09-28 | 2014-02-26 | 上海交通大学 | Multifunctional implanted gastrointestinal electrical stimulation system |
| CA2850444A1 (en) * | 2011-09-30 | 2013-04-25 | Adi Mashiach | Apparatus and method to control an implant |
| CN104689475B (en) * | 2015-03-16 | 2017-09-22 | 北京品驰医疗设备有限公司 | A kind of patient terminal of the remote monitoring system of implantable medical devices |
| CN104645499A (en) * | 2015-03-16 | 2015-05-27 | 北京品驰医疗设备有限公司 | In vitro controller of implantable medical device for patients |
| CN104660717B (en) * | 2015-03-16 | 2018-01-23 | 北京品驰医疗设备有限公司 | A kind of method of work of the remote monitoring system of implantable medical devices |
| CN104683474B (en) * | 2015-03-16 | 2018-01-23 | 北京品驰医疗设备有限公司 | A kind of remote monitoring system of implantable medical devices |
| CN106777915B (en) * | 2016-11-29 | 2021-01-05 | 清华大学 | Data processing method and device based on implantable medical system |
| CN106510688A (en) * | 2016-12-21 | 2017-03-22 | 北京品驰医疗设备有限公司 | Implanted remote monitoring and positioning system |
| CN108257664B (en) * | 2018-01-16 | 2021-07-06 | 北京品驰医疗设备有限公司 | Communication method and device for implantable medical system |
| CN111814133A (en) * | 2020-05-27 | 2020-10-23 | 平安国际智慧城市科技股份有限公司 | Unified login method and device for mobile application |
| CN115487421A (en) * | 2022-09-15 | 2022-12-20 | 首都医科大学附属北京安贞医院 | Cardiac pacemaker system, cardiac pacing control method and electronic equipment |
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- 2022-09-15 CN CN202211123534.4A patent/CN115487421A/en active Pending
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| WO2024055511A1 (en) * | 2022-09-15 | 2024-03-21 | 首都医科大学附属北京安贞医院 | Cardiac pacemaker system, method for controlling cardiac pacing, and electronic device |
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