CN115465559B - Deafness gene screening and detecting kit for otolaryngological department - Google Patents
Deafness gene screening and detecting kit for otolaryngological department Download PDFInfo
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- CN115465559B CN115465559B CN202211409385.8A CN202211409385A CN115465559B CN 115465559 B CN115465559 B CN 115465559B CN 202211409385 A CN202211409385 A CN 202211409385A CN 115465559 B CN115465559 B CN 115465559B
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
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Abstract
The application discloses a deafness gene screening and detecting kit for otolaryngological department, which relates to the technical field of testing equipment and comprises a reagent box body, a storage tube component, an elastic tube and a medium quantity adjusting component; the storage tube assembly comprises a storage tube body provided with exchange holes and a tube body positioning plate densely provided with through holes; the elastic tube is a tube with a closed bottom; the diameter of the elastic tube in a contraction state is less than two thirds of the inner diameter of the storage tube body, and the length of the elastic tube is greater than, less than or equal to the length of the reagent tube to be transferred; the space formed by the elastic tube and the storage tube body is an inner tube space, the space formed by the storage tube body, the tube body positioning plate and the box body main body is an outer tube space, and the storage tube body, the tube body positioning plate and the box body main body are communicated through the exchange hole; the medium quantity adjusting component is used for adjusting the medium quantity in the space in the pipe so as to control the expansion and contraction of the elastic pipe; the deafness gene screening and detecting kit has the advantages of strong applicability to reagent tubes of different models and good damping and protection effects on the reagent tubes in the kit.
Description
Technical Field
The invention relates to the technical field of test equipment, in particular to a deafness gene screening and detecting kit for otolaryngology department.
Background
The hearing deficiency of the newborn brings serious economic and mental burden to the family and the society; in a large number of cities in China, newborn hearing screening is implemented, and if hearing screening fails, gene diagnosis is carried out by starting with deafness genes so as to directly detect whether the molecular structure level and the expression level are abnormal or not, and further judge diseases.
In the gene detection process, a blood sample needs to be extracted and put into a reagent tube, and the sample is transferred and transported to assist the gene detection, so that the deafness gene screening and detecting kit is required to have a certain shock absorption and protection function while having a storage function, but the shock absorption and protection effects of the deafness gene screening and detecting kit in the prior art on the reagent tube are not ideal; in addition, in view of the different sizes of the reagent tubes used in different detection projects, the reagent tubes of different sizes may need to be transported and transferred at the same time, and if the same reagent kit is used to store the reagent tubes of different sizes, confusion is easily caused and the reagent tubes are difficult to fix.
Therefore, a deafness gene screening and detecting kit which has strong applicability to reagent tubes of different models and has good shock absorption and protection effects on the reagent tubes in the kit is needed.
Disclosure of Invention
The embodiment of the application provides a deafness gene screening and detecting kit for the department of otorhinolaryngology, solves the technical problems that the deafness gene screening and detecting kit in the prior art cannot be suitable for reagent tubes of different models due to the fact that the deafness gene screening and detecting kit is limited by the structure of the deafness gene screening and detecting kit, and the protection effect of the deafness gene screening and detecting kit on the reagent tubes of different models is limited, and achieves the technical effects that the deafness gene screening and detecting kit is high in applicability to the reagent tubes of different models and good in shock absorption and protection effects of the reagent tubes in the deafness gene screening and detecting kit.
The embodiment of the application provides a deafness gene screening and detecting kit for otolaryngological department, which comprises a reagent kit body, a storage tube component, an elastic tube and a medium quantity adjusting component, wherein the storage tube component is arranged on the reagent kit body;
the reagent box body comprises a box body main body and an upper cover;
the storage tube assembly comprises a storage tube body provided with an exchange hole and a tube body positioning plate which is fixed on the inner wall of the reagent box body and is densely provided with through holes for fixing the storage tube body;
the elastic tube is a rubber tube with a closed bottom, and the top of the elastic tube is fixed on the top of the storage tube body;
the diameter of the elastic tube in a contraction state is less than two thirds of the inner diameter of the storage tube body, and the length of the elastic tube is greater than, less than or equal to the length of the reagent tube to be transferred;
the space formed by the elastic tube and the storage tube body is an inner space, the space formed by the storage tube body, the tube body positioning plate and the box body main body is an outer space, the storage tube body, the tube body positioning plate and the box body main body are communicated through the exchange hole, and a medium in the storage tube body and the box body main body is gas or liquid;
the medium quantity adjusting assembly is used for adjusting the medium quantity in the space in the pipe so as to control the expansion and contraction of the elastic pipe and comprises a pump body.
Further, the space outside the temporary liquid storage bin inside the space outside the pipe is a liquid storage space;
the liquid temporary storage bin is arranged in the space outside the tube and is a closed space, the liquid storage space and the liquid temporary storage bin are communicated by the pump body, and when the liquid is required to be stored in the reagent tube, the pump body operates to convey part of liquid in the liquid storage space into the liquid temporary storage bin.
Furthermore, a temperature adjusting assembly is positioned in the box body main body and controlled by the control unit, and the temperature adjusting assembly is used for controlling the temperature of the space in the tube and the temperature of the medium in the space outside the tube according to actual requirements and comprises a semiconductor refrigerating sheet.
Preferably, the elastic tube has an upper section and a lower section, the middle part of the elastic tube is positioned with a heat conduction tube body made of metal, and the top and the bottom of the heat conduction tube body are respectively positioned on the upper section and the lower section of the elastic tube.
Preferably, the space in the pipe is provided with a plurality of rubber buffer paraffin capsules, paraffin is filled in the buffer paraffin capsules, and the diameter of the buffer paraffin capsules is 5-8 mm; the buffering paraffin bag floats in the liquid medium and plays a role in buffering and damping.
Preferably, the device also comprises a connecting rope;
the connecting ropes are rope bodies, the number of the connecting ropes is multiple, the connecting ropes have elasticity, one ends of the connecting ropes are fixed at the bottoms of the elastic pipes, and the other ends of the connecting ropes are directly or indirectly fixed on the box body main body;
when taking the reagent pipe, the operation of the medium quality adjusting assembly is controlled, the medium amount in the space in the pipe is increased, and then the reagent pipe is promoted to be lifted, so that the reagent pipe is convenient to take.
Further, the connecting rope is indirectly fixed on the box body main body;
one end of the connecting rope is fixed at the bottom of the elastic tube, and the other end of the connecting rope is fixed at the bottom of the storage tube body.
Further, the connecting rope is directly fixed on the box body main body;
the exchange hole is positioned at the bottom of the storage tube body, and plays a role in conveying media and allowing the connecting rope to penetrate out of the storage tube body;
one end of the connecting rope is fixed at the bottom of the elastic tube, penetrates out of the exchange hole, and the other end of the connecting rope is fixed at the bottom of the box body main body.
Preferably, a balanced floating plate is further arranged in the space outside the pipe, the balanced floating plate is integrally plate-shaped and is fixed on the connecting ropes, all the connecting ropes are fixed on the balanced floating plate, the part of the connecting rope above the balanced floating plate is a non-elastic part without elasticity, and the part of the connecting rope below the balanced floating plate is an elastic part with elasticity.
Preferably, the device also comprises an independent output component;
the independent output assembly comprises a connecting annular plate, an extending column, a positioning pipe body and a pressure spring;
the connecting annular plate is fixed on the pipe orifice of the storage pipe body and is an annular plate, a penetrating hole for inserting the extending column is positioned on the connecting annular plate, and the pipe orifice of the elastic pipe is fixed on the inner ring of the connecting annular plate;
the exchange hole is positioned on the side wall of the storage tube body;
the extending column is inserted into the penetrating hole;
the top of the positioning pipe body is fixed on the connecting annular plate and is arranged close to the side wall of the storage pipe body, the bottom of the positioning pipe body is closed, and the interior of the positioning pipe body is hollow;
the extending column extends into the positioning pipe body through the penetrating hole;
the positioning pipe body is provided with a pipe body opening and a pipe body hole, the pipe body opening is used for communicating the inner space of the positioning pipe body with the inner space of the pipe, and the pipe body hole is used for communicating the inner space of the positioning pipe body with the outer space of the pipe;
the pressure spring is positioned in the positioning pipe body, one end of the pressure spring is abutted against the bottom of the extending column, and the other end of the pressure spring is abutted against the bottom of the positioning pipe body;
during the use, medical personnel push down and stretch into the post and lead to stretching into the post and move down, stretch into the post and can at first shutoff body hole and then seal intraductal space, then along with stretching into moving down of post, the reagent pipe in this elastic tube can be extruded.
One or more technical solutions provided in the embodiments of the present application have at least the following technical effects or advantages:
through improving the deafness gene screening and detecting kit in the prior art, the deafness gene screening and detecting kit comprises a reagent box body, a storage tube component, an elastic tube and a medium quantity adjusting component, wherein the storage tube component comprises a storage tube body fixed on the inner wall of the reagent box body; the elastic tube is a rubber tube with elasticity, is fixed on the storage tube body and is positioned in the storage tube body; when the reagent tube needs to be placed, the medium quantity adjusting assembly is controlled to operate, the elastic tube is attached to the storage tube body by utilizing the atmospheric pressure, and after storage is finished, the medium quantity adjusting assembly is controlled to operate to contract the elastic tube so as to fix the reagent tube; the technical problems that the deafness gene screening detection kit in the prior art cannot be suitable for reagent tubes of different models due to the fact that the deafness gene screening detection kit is limited by the structure of the kit and has a limited protection effect on the reagent tubes in the transportation process are effectively solved, and the technical effects that the deafness gene screening detection kit is high in applicability to the reagent tubes of different models and good in shock absorption and protection effects on the reagent tubes in the deafness gene screening detection kit are achieved.
Drawings
FIG. 1 is an exploded view of the deafness gene screening test kit for otolaryngology department of the present invention;
FIG. 2 is a schematic diagram of the internal structure of the deafness gene screening test kit for the department of otorhinolaryngology of the present invention;
FIG. 3 is a schematic diagram of the appearance structure of the deafness gene screening test kit for the department of otorhinolaryngology of the present invention;
FIG. 4 is a schematic diagram showing the positional relationship between a storage tube body and an elastic tube of the deafness gene screening test kit for otolaryngology department of the present invention;
FIG. 5 is a schematic view of the internal structure of the connecting cord and the storage tube of the deafness gene screening test kit for otolaryngology department of the present invention;
FIG. 6 is a schematic diagram showing the deformation state of the elastic tube of the deafness gene screening test kit for the otolaryngology department of the present invention;
FIG. 7 is a schematic diagram showing the internal structure of the deafness gene screening test kit for otolaryngology department of the present invention;
FIG. 8 is a schematic diagram showing the positional relationship between the buffering paraffin capsule and the elastic tube of the deafness gene screening test kit for otolaryngology department of the present invention;
FIG. 9 is a schematic view showing the communication relationship between the space inside the tube, the space outside the tube and the temporary liquid storage bin of the deafness gene screening test kit for otolaryngology department of the present invention;
FIG. 10 is a schematic diagram of the structure of the flexible tube of the deafness gene screening test kit for otolaryngology department of the present invention;
FIG. 11 is a schematic diagram showing the structure of an independent output component of the deafness gene screening test kit for the otolaryngology department according to the present invention;
FIG. 12 is a schematic diagram of the internal structure of the independent output component of the deafness gene screening test kit for the otolaryngology department of the present invention.
In the figure:
a reagent cartridge 100, a cartridge body 110, and an upper cover 120; a storage tube assembly 200, a storage tube body 210, an exchange hole 211, a tube body positioning plate 220, an in-tube space 230, and an out-tube space 240; an elastic tube 300, a fixing member 310, a heat conductive tube body 320; a temperature adjusting assembly 400, a cooling fin 410; the medium quantity adjusting component 500, the pump body 510 and the liquid temporary storage bin 520; a connecting rope 600, an elastic part 610 and a non-elastic part 620; equalizing the floating plate 700; a buffer paraffin balloon 800; the independent output assembly 900, the connecting annular plate 910, the penetrating hole 911, the extending column 920, the positioning pipe body 930, the pipe body opening 931, the pipe body hole 932 and the pressure spring 940.
Detailed Description
To facilitate an understanding of the invention, the present application will now be described more fully hereinafter with reference to the accompanying drawings; the preferred embodiments of the present invention are illustrated in the accompanying drawings, but the invention may be embodied in many different forms and should not be construed as limited to the embodiments set forth herein; rather, these embodiments are provided so that this disclosure will be thorough and complete.
It is noted that the terms "vertical," "horizontal," "upper," "lower," "left," "right," and the like as used herein are for illustrative purposes only and do not represent the only embodiments.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs; the terminology used herein in the description of the invention is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention; as used herein, the term "and/or" includes any and all combinations of one or more of the associated listed items.
Please refer to fig. 1, which is an exploded view of the deafness gene screening test kit for otolaryngology department of the present invention; the deafness gene screening test kit for the otolaryngological department comprises a reagent kit body 100, a storage tube component 200, an elastic tube 300 and a medium amount adjusting component 500, wherein the storage tube component 200 comprises a storage tube body 210 fixed on the inner wall of the reagent kit body 100; the elastic tube 300 is a rubber tube having elasticity, is fixed to the storage tube body 210, and is located inside the storage tube body 210; when a reagent tube needs to be placed in, the medium quantity adjusting assembly 500 is controlled to operate, the elastic tube 300 is attached to the storage tube body 210 by using atmospheric pressure, and after storage is finished, the medium quantity adjusting assembly 500 is controlled to operate, so that the elastic tube 300 is contracted to fix the reagent tube; the deafness gene screening and detecting kit has the advantages of strong applicability to reagent tubes of different models and good damping and protection effects on the reagent tubes in the kit.
Example one
As shown in FIG. 1, the deafness gene screening test kit for the otolaryngological department of the present application comprises a reagent cartridge 100, a storage tube assembly 200, an elastic tube 300, a medium amount adjusting assembly 500, a power assembly and a control unit.
As shown in fig. 1 to 3, the reagent cartridge 100 is a box structure, has a hollow interior, and includes a cartridge body 110 and an upper cover 120; the cartridge body 110 is a hollow block body with an open top, and the upper cover 120 is positioned above the cartridge body 110.
The storage tube assembly 200 comprises a storage tube body 210 and a tube body positioning plate 220; the storage tube body 210 is tubular, and an exchange hole 211 is formed in the storage tube body, wherein the exchange hole 211 is a through hole; the storage tube body 210 is arranged longitudinally, and the axial direction of the storage tube body is the same as the height direction of the reagent cartridge 100; the storage tube body 210 is provided in plural number, and serves to accommodate the elastic tube 300; the tube positioning plate 220 is fixed on the inner wall of the reagent cartridge 100, and through holes for installing the storage tubes 210 are densely distributed on the tube positioning plate, and the storage tubes 210 are fixed on the through holes.
As shown in fig. 4, the elastic tube 300 is a rubber tube with elasticity and a closed bottom, the top of the elastic tube 300 is fixed on the top of the storage tube body 210 by a fixing member 310, and the fixing member 310 is preferably a metal ring (the metal ring is fixed on the elastic tube 300 and fixed on the storage tube body 210) or a plate with through holes densely distributed (the plate is fixed on the elastic tube 300 and fixed on the storage tube body 210); the diameter of the elastic tube 300 in a contracted state is less than two thirds of the inner diameter of the storage tube body 210; the length of the elastic tube 300 is greater than, less than or equal to the length of the reagent tube to be transferred; for convenience of description, a space formed by the elastic tube 300 and the storage tube body 210 is defined as an inner space 230, and a space formed by the storage tube body 210, the tube positioning plate 220 and the cartridge body 110 is defined as an outer space 240. The tube inner space 230 and the tube outer space 240 communicate through the exchange holes 211.
The medium in the tube inner space 230 and the tube outer space 240 is gas or liquid.
The medium amount adjusting assembly 500 is used for adjusting the amount of the medium in the tube inner space 230 by pumping to control the expansion and contraction of the elastic tube 300, and comprises a pump body 510; if the media in the tube inner space 230 and the tube outer space 240 are air, the pump body 510 is an air pump; if the media in the tube inner space 230 and the tube outer space 240 are liquids, the pump body 510 is a liquid pump.
For convenience of description, the space outside the tube outer space 240 and outside the liquid temporary storage 520 is defined herein as a liquid storage space; further, as shown in fig. 9, a liquid temporary storage bin 520 is disposed in the tube external space 240, the liquid temporary storage bin 520 is a closed space, the liquid pump communicates the liquid storage space with the liquid temporary storage bin 520, and when the liquid needs to be stored in the reagent tube, the liquid pump operates to convey a part of the liquid in the liquid storage space into the liquid temporary storage bin 520.
The power assembly is used for providing power for the operation of each component of the kit, and is preferably a battery; the control unit plays a role in controlling all parts of the kit to run coordinately, and is preferably a programmable logic controller.
Further, in order to improve the sample storage effect, a temperature adjustment assembly 400 is further positioned inside the cartridge body 110, the temperature adjustment assembly 400 is controlled by the control unit, and is used for controlling the temperature of the medium in the in-tube space 230 and the out-of-tube space 240 according to actual requirements, and includes a refrigeration piece 410, and the refrigeration piece 410 is a semiconductor refrigeration piece.
Preferably, as shown in fig. 10, in order to improve the sample preservation effect, the elastic tube 300 has two sections, wherein the middle portion of the elastic tube is located with the heat conducting tube body 320 made of a metal material, and the top and the bottom of the heat conducting tube body 320 are respectively located on the upper section and the lower section of the elastic tube 300.
Preferably, in order to further improve the protective effect of the reagent tube and further reduce the possibility of damage to the reagent tube during transportation, as shown in fig. 8, the tube inner space 230 is provided with a plurality of rubber buffer paraffin capsules 800, the buffer paraffin capsules 800 are filled with paraffin, and the diameter of the buffer paraffin capsules 800 is preferably 5 to 8 mm; (the buffering paraffin pocket 800 is used when the medium in the pipe inner space 230 is liquid) the buffering paraffin pocket 800 floats in the liquid medium, and plays a role of buffering and shock absorption.
When the embodiment of the application is actually used, the steps are as follows in sequence: adjusting the temperature of the medium according to the requirement; opening the upper cover 120, and operating the medium amount adjusting assembly 500 to expand the elastic tube 300 to be closely attached to the inner wall of the storage tube body 210; placing the reagent tube into the elastic tube 300, and then controlling the medium quantity adjusting assembly 500 to operate, so that the elastic tube 300 contracts to wrap the lower half part or the whole part of the reagent tube; the upper cover 120 is covered for transportation; when the storage tube is taken out, the medium quantity adjusting assembly 500 is controlled to operate to expand the elastic tube 300 so as to make the elastic tube 300 tightly attached to the inner wall of the storage tube body 210.
The technical scheme in the embodiment of the application at least has the following technical effects or advantages:
the technical problems that in the prior art, the deafness gene screening and detecting kit is limited by the structure of the kit, so that the kit cannot be suitable for reagent tubes of different models, and the protection effect on the reagent tube in the transportation process is limited are solved, and the technical effects that the deafness gene screening and detecting kit has strong applicability to the reagent tubes of different models and has good shock absorption and protection effects on the reagent tubes in the kit are achieved.
Example two
In view of the above problems, in the deafness gene screening test kit of the embodiment, when the reagent tube is taken, if the length of the elastic tube 300 is longer than that of the reagent tube (the elastic tube 300 is longer than the reagent tube, the reagent tube is completely wrapped by the elastic tube 300 during transportation, which is more beneficial to heat exchange between the reagent tube and the medium in the space 240 outside the reagent tube, and the preservation effect is better), the reagent tube needs to be pinched out by hand when the reagent tube is taken out, which is inconvenient, and in view of the above problems, the connection rope 600 is additionally provided on the basis of the embodiment, and the taking steps of the reagent tube are changed, specifically:
as shown in fig. 4 to 6, the connection string 600 is a plurality of string bodies, has elasticity, one end thereof is fixed to the bottom of the elastic tube 300, the other end thereof is directly or indirectly fixed to the cassette body 110, and the axial direction of the connection string 600 is the same as or approximately the same as that of the reagent cassette 100 (the angle difference is not more than 30 degrees); when taking out the reagent tube, the medium quantity adjusting assembly 500 is controlled to operate, so as to increase the medium quantity in the tube inner space 230, thereby promoting the reagent tube to be lifted (as shown in fig. 6) and facilitating the taking out of the reagent tube.
Preferably, as shown in fig. 4, the connection string 600 is indirectly fixed to the case body 110; one end of the connection string 600 is fixed to the bottom of the elastic tube 300, and the other end is fixed to the bottom of the storage tube body 210 (since the connection string 600 is fixed to the bottom of the storage tube body 210, and the storage tube body 210 is fixed to the case body 110 through the tube body positioning plate 200, the connection string 600 is indirectly fixed to the case body 110).
Preferably, as shown in fig. 5, the connection string 600 is directly fixed on the cartridge body 110; the exchange hole 211 is located at the bottom of the storage tube body 210; one end of the connection string 600 is fixed to the bottom of the elastic tube 300, penetrates through the exchange hole 211, and the other end is fixed to the bottom of the box body 110.
Considering that in actual use, if a reagent tube is not placed (not filled) in a part of the elastic tube 300 in the reagent cartridge 100, when the reagent tube is taken out, the operation of the medium quantity adjusting assembly 500 further increases the medium quantity in the tube inner space 230, which may cause the elastic tube 300 without the reagent tube to expand, and affect the normal taking of the reagent tube; as shown in fig. 7, preferably, a balance floating plate 700 is further disposed in the outer space 240 of the pipe (the balance floating plate 700 is used in cooperation with the scheme that "the connection rope 600 is directly fixed on the box body 110"), and the balance floating plate 700 is integrally plate-shaped, is fixed on the connection rope 600, is preferably located in the middle of the connection rope 600, and is preferably made of rubber; all the connection ropes 600 are fixed on the uniform floating plate 700, the connection rope 600 portion above the uniform floating plate 700 is a non-elastic portion 620 having no elastic force, and the connection rope 600 portion below the uniform floating plate 700 is an elastic portion 610 having elastic force, so that the uniform floating plate 700 plays a role of equalizing the amount of upward movement of each elastic tube 300 (facilitating taking of reagent tubes) in actual use.
EXAMPLE III
In the actual medical working process, the situation that the individual reagent tube needs to be taken out separately is sometimes encountered, and the detection kit in the scheme is difficult to take out the individual reagent tube separately when the reagent tube is taken out (the medium quantity adjusting component 500 needs to be controlled to take out the individual reagent tube, and the medium quantity in all the tube inner spaces 230 is changed); in order to improve the practicability of the test kit, an independent output assembly 900 is added on the basis of the embodiment of the present application, specifically, the embodiment of the present application is as follows;
as shown in fig. 11 and 12, the independent output assembly 900 includes a connecting annular plate 910, an extending post 920, a positioning tubular body 930, and a compression spring 940;
the connecting annular plate 910 is fixed on the nozzle of the storage tube body 210 and is an annular plate; a penetrating hole 911 for inserting the extending column 920 is positioned on the connecting annular plate 910, and a sealing ring is positioned on the inner wall of the penetrating hole 911; the orifice of the elastic tube 300 is fixed on the inner ring of the connecting annular plate 910;
the exchange holes 211 are located on the side wall of the storage tube body 210, and the liquid level in the tube outer space 240 is higher than the exchange holes 211;
the extending column 920 is inserted into the penetrating hole 911, and the length of the extending column 920 is two thirds or more of the length of the elastic tube 300 before expansion;
the top of the positioning tube 930 is fixed on the connecting ring plate 910 and is disposed closely to the sidewall of the storage tube 210, and the bottom is closed and has a hollow interior; the extension column 920 extends into the positioning tube 930 through the penetration hole 911; the positioning tube 930 is provided with a tube opening 931 and a tube hole 932, the tube opening 931 connects the inner space of the positioning tube 930 with the tube space 230; the tube holes 932 communicate the inner space of the positioning tube 930 with the tube outer space 240;
the pressure spring 940 is positioned inside the positioning tube 930, one end of the pressure spring abuts against the bottom of the extending column 920, and the other end of the pressure spring abuts against the bottom of the positioning tube 930;
during the in-service use, medical personnel push down and stretch into post 920 and lead to stretching into post 920 and move down, stretch into post 920 and can at first block up body hole 932 and then seal intraductal space 230, and then along with stretching into the moving down of post 920, the reagent pipe in this elastic tube 300 can be extruded.
The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention, and various modifications and changes may be made by those skilled in the art. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.
Claims (10)
1. A deafness gene screening and detecting kit for department of otolaryngology comprises a reagent kit body (100), and is characterized in that: further comprises a storage tube assembly (200), an elastic tube (300) and a medium amount adjusting assembly (500);
the reagent cartridge (100) comprises a cartridge body (110) and an upper cover (120);
the storage tube assembly (200) comprises a storage tube body (210) provided with an exchange hole (211) and a tube body positioning plate (220) which is fixed on the inner wall of the reagent box body (100) and is densely provided with through holes for fixing the storage tube body (210);
the elastic tube (300) is a rubber tube with a closed bottom, and the top of the elastic tube (300) is fixed on the top of the storage tube body (210);
the diameter of the elastic tube (300) in a contraction state is less than two thirds of the inner diameter of the storage tube body (210), and the length of the elastic tube is greater than, less than or equal to the length of a reagent tube to be transferred;
the space formed by the elastic tube (300) and the storage tube body (210) is an inner tube space (230), the space formed by the storage tube body (210), the tube body positioning plate (220) and the box body main body (110) is an outer tube space (240), the inner tube space and the outer tube space are communicated through the exchange hole (211), and media in the inner tube space and the outer tube space are gas or liquid;
the medium quantity adjusting assembly (500) is used for adjusting the medium quantity in the tube inner space (230) so as to control the expansion and contraction of the elastic tube (300) and comprises a pump body (510).
2. The gene screening test kit for deafness of the otolaryngological department of claim 1, wherein: the space outside the tube outer space (240) and outside the internal liquid temporary storage bin (520) is used as a liquid storage space;
the liquid temporary storage bin (520) is arranged in the pipe outer space (240), the liquid temporary storage bin (520) is a closed space, the liquid storage space and the liquid temporary storage bin (520) are communicated through the pump body (510), and when the liquid is required to be stored in the reagent pipe, the pump body (510) operates to convey part of liquid in the liquid storage space into the liquid temporary storage bin (520).
3. The gene screening test kit for deafness of the otolaryngological department of claim 1, wherein: the temperature adjusting assembly (400) is further positioned inside the box body main body (110), and the temperature adjusting assembly (400) is controlled by the control unit and is used for controlling the temperature of media in the space (230) in the pipe and the space (240) outside the pipe according to actual requirements and comprises a semiconductor refrigerating sheet.
4. The gene screening test kit for deafness of the otolaryngological department of claim 1, wherein: the elastic tube (300) is divided into an upper section and a lower section, a heat conduction tube body (320) made of metal is positioned in the middle of the elastic tube, and the top and the bottom of the heat conduction tube body (320) are respectively positioned on the upper section and the lower section of the elastic tube (300).
5. The gene screening test kit for deafness of the otolaryngological department of claim 1, wherein: the inner space (230) of the tube is provided with a plurality of rubber buffer paraffin capsules (800), and paraffin is filled in the buffer paraffin capsules (800) and the diameter of the buffer paraffin capsules is 5-8 mm; the buffering paraffin bag (800) floats in a liquid medium and plays a role in buffering and damping.
6. The gene screening test kit for deafness of the otolaryngological department according to any one of claims 1 to 5, wherein: also comprises a connecting rope (600);
the connecting ropes (600) are rope bodies, are multiple in number, have elasticity, and are fixed at the bottoms of the elastic tubes (300) at one ends and directly or indirectly fixed on the box body main body (110) at the other ends;
when taking the reagent tube, the medium quantity adjusting assembly (500) is controlled to operate, the medium quantity in the tube inner space (230) is increased, and then the reagent tube is promoted to be lifted, so that the reagent tube is convenient to take.
7. The gene screening test kit for deafness of the otolaryngological department of claim 6, wherein:
the connecting rope (600) is indirectly fixed on the box body main body (110);
one end of the connecting rope (600) is fixed at the bottom of the elastic tube (300), and the other end of the connecting rope is fixed at the bottom of the storage tube body (210).
8. The gene screening test kit for deafness of the otolaryngological department of claim 6, wherein: the connecting rope (600) is directly fixed on the box body main body (110);
the exchange hole (211) is positioned at the bottom of the storage tube body (210) and plays a role of conveying media and simultaneously allowing the connecting rope (600) to penetrate out of the storage tube body (210);
one end of the connecting rope (600) is fixed at the bottom of the elastic tube (300), penetrates out of the exchange hole (211), and the other end of the connecting rope is fixed at the bottom of the box body main body (110).
9. The gene screening test kit for deafness of the otolaryngological department of claim 8, wherein: the pipe outer space (240) is also internally provided with a balanced floating plate (700), the balanced floating plate (700) is integrally plate-shaped and is fixed on the connecting ropes (600), all the connecting ropes (600) are fixed on the balanced floating plate (700), the part of the connecting ropes (600) above the balanced floating plate (700) is a non-elastic part (620) without elasticity, and the part of the connecting ropes (600) below the balanced floating plate (700) is an elastic part (610) with elasticity.
10. The gene screening test kit for deafness of the otolaryngological department of claim 6, wherein: further comprising an independent output assembly (900);
the independent output assembly (900) comprises a connecting ring-shaped plate (910), an extending column (920), a positioning pipe body (930) and a pressure spring (940);
the connection annular plate (910) is fixed on the nozzle of the storage tube body (210) and is an annular plate, a penetrating hole (911) for inserting and extending into a column (920) is positioned on the annular plate, and the nozzle of the elastic tube (300) is fixed on the inner ring of the connection annular plate (910);
the exchange hole (211) is positioned on the side wall of the storage tube body (210);
the extending column (920) is inserted into the penetrating hole (911);
the top of the positioning tube body (930) is fixed on the connecting ring-shaped plate (910) and is arranged close to the side wall of the storage tube body (210), and the bottom of the positioning tube body is closed and is hollow;
the extending column (920) extends into the positioning pipe body (930) through a penetrating hole (911);
the positioning pipe body (930) is provided with a pipe body opening (931) and a pipe body hole (932), the pipe body opening (931) is used for communicating the inner space of the positioning pipe body (930) with the pipe inner space (230), and the pipe body hole (932) is used for communicating the inner space of the positioning pipe body (930) with the pipe outer space (240);
the pressure spring (940) is positioned inside the positioning pipe body (930), one end of the pressure spring is abutted against the bottom of the extending column (920), and the other end of the pressure spring is abutted against the bottom of the positioning pipe body (930);
during the use, medical personnel push down and stretch into post (920) and lead to stretching into post (920) and move down, stretch into post (920) and can at first shutoff body hole (932) and then seal intraductal space (230), then along with stretching into moving down of post (920), the reagent pipe in this elastic tube (300) can be extruded.
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| CN202211409385.8A CN115465559B (en) | 2022-11-11 | 2022-11-11 | Deafness gene screening and detecting kit for otolaryngological department |
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| CN115465559B true CN115465559B (en) | 2023-02-24 |
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