CN115445056A - Stent delivery guide wire and preparation method thereof - Google Patents
Stent delivery guide wire and preparation method thereof Download PDFInfo
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- CN115445056A CN115445056A CN202211059201.XA CN202211059201A CN115445056A CN 115445056 A CN115445056 A CN 115445056A CN 202211059201 A CN202211059201 A CN 202211059201A CN 115445056 A CN115445056 A CN 115445056A
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- distal
- developing
- stent delivery
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- 238000002360 preparation method Methods 0.000 title description 4
- HZEWFHLRYVTOIW-UHFFFAOYSA-N [Ti].[Ni] Chemical group [Ti].[Ni] HZEWFHLRYVTOIW-UHFFFAOYSA-N 0.000 claims abstract description 17
- 238000000034 method Methods 0.000 claims abstract description 11
- 229910052751 metal Inorganic materials 0.000 claims description 23
- 239000002184 metal Substances 0.000 claims description 23
- RVTZCBVAJQQJTK-UHFFFAOYSA-N oxygen(2-);zirconium(4+) Chemical compound [O-2].[O-2].[Zr+4] RVTZCBVAJQQJTK-UHFFFAOYSA-N 0.000 claims description 18
- 238000011161 development Methods 0.000 claims description 14
- 238000005476 soldering Methods 0.000 claims description 10
- 238000012800 visualization Methods 0.000 claims description 7
- 229910001080 W alloy Inorganic materials 0.000 claims description 5
- 238000004026 adhesive bonding Methods 0.000 claims description 5
- 238000004519 manufacturing process Methods 0.000 claims description 5
- 229910000566 Platinum-iridium alloy Inorganic materials 0.000 claims description 4
- 238000002788 crimping Methods 0.000 claims description 4
- ZONODCCBXBRQEZ-UHFFFAOYSA-N platinum tungsten Chemical compound [W].[Pt] ZONODCCBXBRQEZ-UHFFFAOYSA-N 0.000 claims description 4
- HWLDNSXPUQTBOD-UHFFFAOYSA-N platinum-iridium alloy Chemical class [Ir].[Pt] HWLDNSXPUQTBOD-UHFFFAOYSA-N 0.000 claims description 4
- 238000003466 welding Methods 0.000 claims description 4
- 229910000990 Ni alloy Inorganic materials 0.000 claims description 3
- PCLURTMBFDTLSK-UHFFFAOYSA-N nickel platinum Chemical compound [Ni].[Pt] PCLURTMBFDTLSK-UHFFFAOYSA-N 0.000 claims description 3
- 230000018109 developmental process Effects 0.000 description 10
- 230000008569 process Effects 0.000 description 4
- 206010002329 Aneurysm Diseases 0.000 description 3
- 210000004204 blood vessel Anatomy 0.000 description 3
- 238000010586 diagram Methods 0.000 description 3
- 208000024172 Cardiovascular disease Diseases 0.000 description 2
- 208000031481 Pathologic Constriction Diseases 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- 238000003825 pressing Methods 0.000 description 2
- 208000037804 stenosis Diseases 0.000 description 2
- 230000036262 stenosis Effects 0.000 description 2
- 208000007536 Thrombosis Diseases 0.000 description 1
- ATJFFYVFTNAWJD-UHFFFAOYSA-N Tin Chemical compound [Sn] ATJFFYVFTNAWJD-UHFFFAOYSA-N 0.000 description 1
- 206010057469 Vascular stenosis Diseases 0.000 description 1
- 230000001133 acceleration Effects 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 229910045601 alloy Inorganic materials 0.000 description 1
- 239000000956 alloy Substances 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 208000026106 cerebrovascular disease Diseases 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000002059 diagnostic imaging Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 239000003292 glue Substances 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 230000002008 hemorrhagic effect Effects 0.000 description 1
- 238000002513 implantation Methods 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 230000000302 ischemic effect Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- HLXZNVUGXRDIFK-UHFFFAOYSA-N nickel titanium Chemical group [Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni] HLXZNVUGXRDIFK-UHFFFAOYSA-N 0.000 description 1
- 230000002980 postoperative effect Effects 0.000 description 1
- 238000012797 qualification Methods 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 230000033764 rhythmic process Effects 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 230000008733 trauma Effects 0.000 description 1
- 208000019553 vascular disease Diseases 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/09—Guide wires
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
- A61F2002/9505—Instruments specially adapted for placement or removal of stents or stent-grafts having retaining means other than an outer sleeve, e.g. male-female connector between stent and instrument
- A61F2002/9511—Instruments specially adapted for placement or removal of stents or stent-grafts having retaining means other than an outer sleeve, e.g. male-female connector between stent and instrument the retaining means being filaments or wires
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
- A61F2250/0096—Markers and sensors for detecting a position or changes of a position of an implant, e.g. RF sensors, ultrasound markers
- A61F2250/0098—Markers and sensors for detecting a position or changes of a position of an implant, e.g. RF sensors, ultrasound markers radio-opaque, e.g. radio-opaque markers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/09—Guide wires
- A61M2025/09108—Methods for making a guide wire
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2210/00—Anatomical parts of the body
- A61M2210/12—Blood circulatory system
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Biophysics (AREA)
- Pulmonology (AREA)
- Anesthesiology (AREA)
- Hematology (AREA)
- Media Introduction/Drainage Providing Device (AREA)
Abstract
The present disclosure provides a stent delivery guidewire and a method for preparing the same, the stent delivery guidewire comprising: the device comprises a hypotube and a nickel-titanium core wire, wherein one end of the hypotube is connected with one end of the nickel-titanium core wire; the nickel-titanium core wire is provided with a far-end first developing area and a far-end second developing area, and the distance between the far-end first developing area and the far-end second developing area is set. Adopt the circular spring structure of constant diameter or develop the becket in this disclosure for developing the district, at the in-process of equipment, the circular spring of constant diameter and develop the becket all be difficult for damaging, have reduced the equipment degree of difficulty of spring.
Description
Technical Field
The disclosure relates to the technical field of medical instruments, in particular to a stent delivery guide wire and a preparation method thereof.
Background
Along with the aging of population, the improvement of substance level, the change of national life style, the acceleration of social rhythm, the diversification of psychological pressure, the increase of the incidence of cardiovascular diseases year by year, and the fatality rate represented by cerebrovascular diseases, which exceeds malignant tumors, become the first killer harmful to national health. The youth and diversification of cardiovascular diseases are also attracting increasing attention.
Common vascular diseases include ischemic stenosis and hemorrhagic aneurysm. With the popularization of minimally invasive intervention medicine, the technical progress of medical instruments, the improvement of national consciousness, small trauma, short operation time, quick postoperative recovery, low operation risk and cost and other advantages, the minimally invasive intervention gradually replaces the traditional surgical operation and is rapidly developed. The products of catheters, guide wires, balloons, stents and the like in the process of minimally invasive interventional operation cover most of the instruments for interventional or implantation in the operation. With the aid of medical imaging equipment, a blood vessel access is established through arterial or venous puncture, and the device is delivered to a target blood vessel position, so that the expansion of clinical common blood vessel stenosis, the removal of thrombus, the treatment of aneurysm occlusion and other diseases are finally realized. The stent product is particularly important in clinic as a common stent product for treating aneurysm and vascular stenosis.
Patent No. CN112717259a discloses a pushwire and a method of manufacturing the pushwire, the pushwire comprising: the core wire is sequentially provided with a first section, a second section and a third section along the direction from the far end to the near end of the conveying guide wire, and the diameters of the first section, the second section and the third section are sequentially increased. A metal ring is at least partially disposed at the proximal end of the first segment. The spring is at least partially sleeved outside the second section, the far end of the spring is connected with the near end of the metal ring, and the diameter of the far end area of the spring is smaller than that of the near end area of the spring. The patent states that the far end of the spring ring is fixed by nesting the metal ring, the fixing mode of the spring and the metal ring is changed only from the side, but the assembling difficulty of the spring and the metal ring is increased, so that the spring is easy to damage or destroy in the assembling process, and the qualification rate is influenced; meanwhile, the spring adopts a reducing design, so that the manufacturing difficulty of the spring is increased.
Disclosure of Invention
The invention provides a stent conveying guide wire and a preparation method thereof, which can solve the problem that the manufacturing difficulty of a spring is increased by a reducing spring. In order to solve the technical problem, the present disclosure provides the following technical solutions: a stent delivery guidewire comprising: a hypotube and nitinol core wire; one end of the hypotube is connected with one end of the nickel-titanium core wire; the nickel-titanium core wire is provided with a far-end first developing area and a far-end second developing area, and the distance between the far-end first developing area and the far-end second developing area is set.
Optionally, the distal first developing zone and the distal second developing zone each employ one of a developing coil or a developing metal ring.
Optionally, the developing spring ring and the developing metal ring are made of one of platinum-tungsten alloy, platinum-nickel alloy or platinum-iridium alloy.
Optionally, the distal first developing zone and the distal second developing zone each employ one of a circular shape or a prismatic shape.
Optionally, the distal first and second developing zones each have a length of 0.5mm to 3.0mm.
Optionally, the developer spring ring is fixed to the nitinol wire by soldering.
Optionally, the visualization metal ring is fixed on the nitinol wire by crimping.
According to another aspect of the embodiments of the present disclosure, there is provided a method for preparing a stent delivery guidewire based on the above, including the following steps:
connecting one end of the hypotube to one end of the nitinol wire;
sleeving the distal second developing area and the distal first developing area into the nitinol wire in sequence;
and fixing the first distal developed area and the second distal developed area on the nitinol wire at intervals.
Optionally, the connection of one end of the hypotube to one end of the nitinol wire includes laser welding, thread fastening, flip-chip fastening, glue bonding, or soldering.
Optionally, the means by which the distal first developed area and the distal second developed area are affixed to the nitinol wire includes soldering, glue or crimping.
The beneficial effects of this disclosure are: adopt the circular spring structure of constant diameter or develop the becket in this disclosure for developing the district, at the in-process of equipment, the circular spring of constant diameter and develop the becket all be difficult for damaging, have reduced the equipment degree of difficulty of spring.
Drawings
FIG. 1 is a schematic diagram of a developing spring ring structure in both a first developing zone and a second developing zone; (ii) a
FIG. 2 is a schematic diagram showing a structure in which a first developing area is a developing coil and a second developing area is a developing metal ring;
FIG. 3 schematically illustrates a first development zone as a prismatic structured image;
FIG. 4 is a system diagram of a stent delivery guidewire and method of making the same;
1. the device comprises a first developing area, a second developing area, a nickel-titanium core wire 3, an intersection area 4 and a hypotube 5.
Detailed Description
The technical solutions in the embodiments of the present disclosure will be clearly and completely described below with reference to the drawings in the embodiments of the present disclosure, and it is obvious that the described embodiments are only a part of the embodiments of the present disclosure, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments disclosed herein without making any creative effort, shall fall within the protection scope of the present disclosure.
Example 1
The present embodiment provides a stent delivery guidewire, referring to fig. 1-3, comprising: a hypotube 5 and a nitinol wire 3; one end of the hypotube 5 is connected with one end of the nickel-titanium core wire 3, the connection position of the hypotube and the nickel-titanium core wire is a cross connection area 4, and the connection mode comprises one of laser welding, thread fixing, back-off fixing, glue bonding or tin soldering; the nickel-titanium core wire 3 is provided with a far-end first developing area 1 and a far-end second developing area 2, and the distance between the far-end first developing area 1 and the far-end second developing area 2 is set.
In some embodiments, the distal first development zone 1 and the distal second development zone 2 are each one of a development coil or a development metal ring, and if a development coil is used, are fixed to the nitinol wire 3 by soldering; if the developing metal ring is adopted, the developing metal ring is fixed on the nickel-titanium core wire 3 through pressing and holding, and the developing spring ring or the developing metal ring is of an equal-diameter structure, so that the developing spring ring or the developing metal ring is not easy to damage in the assembling process, and the assembling difficulty of the spring is reduced.
In some embodiments, the developing spring ring and the developing metal ring are made of an alloy, such as platinum-iridium alloy, platinum-tungsten alloy, huang Jinsi, platinum-nickel alloy or tungsten alloy, and the developing metal ring is preferably made of platinum-iridium alloy or platinum-tungsten alloy.
In some embodiments, the distal first development zone 1 is circular or prismatic and the distal second development zone 2 is circular.
In some embodiments, the distal first development zone 1 and the distal second development zone 2 are each 0.5mm to 3.0mm in length, preferably 1.0mm to 2.0mm in this embodiment.
Example 2
This embodiment provides a method for preparing a stent delivery guidewire based on example 1, as shown in fig. 4, including the following steps:
s1, connecting one end of the hypotube 5 with one end of the nickel-titanium core wire 3;
s2, sequentially sleeving the far-end second developing area 2 and the far-end first developing area 1 into the nickel-titanium core wire 3;
s3, fixing the far-end first developing area 1 and the far-end second developing area 2 on the nickel-titanium core wire 3 at intervals.
In some embodiments, the connecting of the one end of the hypotube 5 to the one end of the nitinol wire 3 in step S1 includes one of laser welding, thread fastening, flip-chip fastening, glue bonding, or soldering.
In some embodiments, in step S3, the distal first developing area 1 and the distal second developing area 2 are both fixed to the nitinol wire 3 by soldering using one of a developing coil or a developing metal ring, if a developing coil is used; if the developing metal ring is adopted, the developing metal ring is fixed on the nickel-titanium core wire 3 through pressing and holding, and the developing spring ring or the developing metal ring is of an equal-diameter structure, so that the developing spring ring or the developing metal ring is not easy to damage in the assembling process, and the assembling difficulty of the spring is reduced.
Although embodiments of the present disclosure have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations may be made in these embodiments without departing from the principles and spirit of the disclosure, the scope of which is defined in the appended claims and their equivalents.
Claims (10)
1. A stent delivery guidewire, comprising: the device comprises a hypotube and a nickel-titanium core wire, wherein one end of the hypotube is connected with one end of the nickel-titanium core wire; the nickel-titanium core wire is provided with a far-end first developing area and a far-end second developing area, and the distance between the far-end first developing area and the far-end second developing area is set.
2. The stent delivery guidewire of claim 1, wherein the distal first development zone and the distal second development zone each employ one of a developing coil or a developing ring.
3. The stent delivery guidewire of claim 2, wherein the visualization spring ring and the visualization metal ring each comprise one of a platinum-tungsten alloy, a platinum-nickel alloy, or a platinum-iridium alloy.
4. The stent delivery guidewire of claim 2 or 3, wherein the distal first development zone and the distal second development zone each have one of a rounded shape or a prismatic shape.
5. The stent delivery guidewire of claim 2 or 3, wherein the distal first visualization region and the distal second visualization region each have a length of 0.5mm to 3.0mm.
6. The stent delivery guidewire of claim 2 or 3, wherein the visualization coil is secured to the nitinol wire by soldering.
7. The stent delivery guidewire of claim 2 or 3, wherein the visualization metal loop is secured to the nitinol wire by crimping.
8. The method of making a stent delivery guidewire as in any one of claims 1-7, comprising the steps of:
connecting one end of the hypotube to one end of the nitinol wire;
sleeving the distal second developing area and the distal first developing area into the nitinol wire in sequence;
and fixing the first distal developed area and the second distal developed area on the nitinol wire at intervals.
9. The method of claim 8, wherein the connecting the one end of the hypotube to the one end of the nitinol wire comprises laser welding, thread fastening, flip-chip fastening, glue bonding, or soldering.
10. The method of claim 8, wherein the securing the distal first developed area and the distal second developed area to the nitinol wire comprises soldering, gluing, or crimping.
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CN202211059201.XA CN115445056B (en) | 2022-08-31 | 2022-08-31 | Stent delivery guide wire and preparation method thereof |
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CN202211059201.XA CN115445056B (en) | 2022-08-31 | 2022-08-31 | Stent delivery guide wire and preparation method thereof |
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CN115445056B CN115445056B (en) | 2024-04-26 |
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Citations (7)
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---|---|---|---|---|
US20080033423A1 (en) * | 2005-02-02 | 2008-02-07 | Peacock James C Iii | Total vascular occlusion treatment system and method |
US20130023853A1 (en) * | 2010-02-05 | 2013-01-24 | Microport Medical (Shanghai) Co., Ltd | Medical guide wire |
CN105078615A (en) * | 2012-09-21 | 2015-11-25 | 上海微创医疗器械(集团)有限公司 | Inner tube assembly for implant delivery system |
CN206045152U (en) * | 2016-04-07 | 2017-03-29 | 叶芳余 | A kind of multifunctional medical seal wire |
CN211243922U (en) * | 2019-08-29 | 2020-08-14 | 北京泰杰伟业科技有限公司 | Conveying device for conveying peripheral blood vessel self-expanding type stent |
CN112717259A (en) * | 2021-01-13 | 2021-04-30 | 微创神通医疗科技(上海)有限公司 | Delivery guidewire and method of making same |
CN213642756U (en) * | 2020-09-29 | 2021-07-09 | 上海康德莱医疗器械股份有限公司 | Gauge length seal wire |
-
2022
- 2022-08-31 CN CN202211059201.XA patent/CN115445056B/en active Active
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20080033423A1 (en) * | 2005-02-02 | 2008-02-07 | Peacock James C Iii | Total vascular occlusion treatment system and method |
US20130023853A1 (en) * | 2010-02-05 | 2013-01-24 | Microport Medical (Shanghai) Co., Ltd | Medical guide wire |
CN105078615A (en) * | 2012-09-21 | 2015-11-25 | 上海微创医疗器械(集团)有限公司 | Inner tube assembly for implant delivery system |
CN206045152U (en) * | 2016-04-07 | 2017-03-29 | 叶芳余 | A kind of multifunctional medical seal wire |
CN211243922U (en) * | 2019-08-29 | 2020-08-14 | 北京泰杰伟业科技有限公司 | Conveying device for conveying peripheral blood vessel self-expanding type stent |
CN213642756U (en) * | 2020-09-29 | 2021-07-09 | 上海康德莱医疗器械股份有限公司 | Gauge length seal wire |
CN112717259A (en) * | 2021-01-13 | 2021-04-30 | 微创神通医疗科技(上海)有限公司 | Delivery guidewire and method of making same |
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