CN115444623B - Composite venous valve - Google Patents
Composite venous valve Download PDFInfo
- Publication number
- CN115444623B CN115444623B CN202211222423.9A CN202211222423A CN115444623B CN 115444623 B CN115444623 B CN 115444623B CN 202211222423 A CN202211222423 A CN 202211222423A CN 115444623 B CN115444623 B CN 115444623B
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- China
- Prior art keywords
- valve
- composite
- leaflet
- free edge
- substrate
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2475—Venous valves
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Abstract
The invention discloses a composite venous valve, which comprises a substrate and a composite valve leaflet, wherein one part of the edge of the composite valve leaflet is a fixed edge, the other part of the edge of the composite valve leaflet is a free edge, the fixed edge is fixedly connected to the substrate, a choke cavity is formed between the composite valve leaflet and the substrate, a choke cavity inlet is formed between the free edge and the substrate, the free edge can be switched between a first state and a second state under the pressure of a blood vessel, the first state is a state when the free edge moves close to the substrate to close the inlet, and the second state is a state when the free edge moves away from the substrate to open the inlet; the composite leaflet includes first and second leaflets that are interconnected, with the seam ends of the first and second leaflets extending to two points of engagement of the fixed edge and the free edge, respectively, the free edge being on the first leaflet, the fixed edge being on the second leaflet, and the first leaflet She Xiaoyu being the thickness of the second leaflet. The invention can improve the functionality of the valve and more flexibly exert the unidirectional circulation function of the valve.
Description
Technical Field
The invention relates to the technical field of implantable medical devices, in particular to a composite venous valve.
Background
Venous valves exist within the venous blood vessels of mammals, which prevent blood back flow during circulation. When the venous valve is damaged and cannot exert its backflow preventing function, blood flows back in the veins and stagnates in the legs, and the blood stagnates and causes vein dilation, thereby causing further failure of the venous valve and causing chronic venous insufficiency of the human body.
In the prior art, an implantable venous valve is used for replacing an original damaged valve of a patient, the existing implantable venous valve is generally formed by fixedly connecting a prosthetic valve in a vascular stent, and then implanting the whole structure into a venous vessel to simulate the function of a human valve. However, the existing implantable venous valve is generally made of bovine pericardium materials, when the bovine pericardium is used for making the valve, the making thickness of the valve is difficult to be less than 0.3mm, after the thicker valve is implanted into a blood vessel, the valve is not easy to open when blood flows through the valve due to weak venous flow, the flexibility is poor, the blood flow is not easy to pass, and the valve is not easy to be opened to close when the blood flows back, so that the backflow preventing effect is poor, and the functionality of the valve needs to be improved.
Disclosure of Invention
The invention aims to provide a composite venous valve, which solves the problems in the prior art, can improve the functionality of the valve and can more flexibly exert the unidirectional circulation function of the valve.
In order to achieve the above object, the present invention provides the following solutions:
the invention provides a composite venous valve, which comprises a substrate and a composite valve leaflet, wherein one part of the edge of the composite valve leaflet is a fixed edge, the other part of the edge of the composite valve leaflet is a free edge, the fixed edge is fixedly connected to the substrate, a choke cavity is formed between the composite valve leaflet and the substrate, an inlet of the choke cavity is formed between the free edge and the substrate, the free edge can be freely switched between a first state and a second state under the action of intravascular pressure, the first state is a state when the free edge moves close to the substrate to close the inlet, and the second state is a state when the free edge moves away from the substrate to open the inlet; the composite leaflet comprises a first leaflet and a second leaflet which are connected with each other, wherein two ends of a seam formed by connecting the first leaflet and the second leaflet respectively extend to two connection points of the fixed edge and the free edge, the free edge is positioned on the first leaflet, the fixed edge is positioned on the second leaflet, and the thickness of the first leaflet is smaller than that of the second leaflet.
Preferably, the device further comprises a bracket, wherein the substrate is fixedly attached to the inner wall of the bracket in a fitting way, and the bracket is used for being supported on the inner wall of the blood vessel in a fitting way.
Preferably, the inner wall of the bracket is provided with one substrate, the substrate is provided with one composite valve blade, when the free edge is in a first state, an overcurrent gap exists between the composite valve blade and the inner wall of the bracket, and when the free edge is in a second state, the free edge is attached to the inner wall of the bracket.
Preferably, the inner wall of the bracket is symmetrically provided with two substrates, each substrate is provided with one composite valve leaf, when the free edge of each composite valve leaf is in a first state, an overcurrent gap exists between the two composite valve leaves, and when the free edge of each composite valve leaf is in a second state, the first valve leaves of the two composite valve leaves are mutually attached.
Preferably, the first valve leaflet is made of a polymer material, and the second valve leaflet is made of a biological material or a polymer material.
Preferably, the polymer material is TPU material, and the biological material is bovine pericardium.
Preferably, the thickness of the first leaflet is less than 0.3mm.
Preferably, the thickness of the first leaflet is 0.02-0.2 mm.
Preferably, the first leaflet is fixedly connected with the second leaflet by stitching, and the first leaflet is fixedly connected with the base by stitching.
Compared with the prior art, the invention has the following technical effects:
the invention provides a composite venous valve, wherein when blood flows through the valve, a first valve leaf can move to the base side more flexibly under the action of the blood flow, so that the valve is easier to open, blood flow can pass through the valve more easily, and when blood flows back, the first valve leaf can move away from the base more flexibly under the action of the blood flow, so that the inlet of a choke cavity can be opened more easily, blood flows into the choke cavity to stop bleeding back, the functionality of the valve is improved, and the unidirectional circulation function of the valve is exerted more flexibly.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings that are needed in the embodiments will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and other drawings may be obtained according to these drawings without inventive effort for a person skilled in the art.
FIG. 1 is a schematic view of a composite venous valve according to the present invention;
in the figure: 100-composite venous valve, 1-base, 2-composite leaflet, 3-fixed edge, 4-free edge, 5-flow-blocking lumen, 6-inlet, 7-first leaflet, 8-second leaflet, 9-seam, 10-commissure.
Detailed Description
The following description of the embodiments of the present invention will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
The invention aims to provide a composite venous valve, which solves the problems in the prior art, can improve the functionality of the valve and can more flexibly exert the unidirectional circulation function of the valve.
In order that the above-recited objects, features and advantages of the present invention will become more readily apparent, a more particular description of the invention will be rendered by reference to the appended drawings and appended detailed description.
As shown in fig. 1, the present embodiment provides a composite venous valve 100, which includes a base 1 and a composite leaflet 2, wherein a part of the edge of the composite leaflet 2 is a fixed edge 3, and the other part is a free edge 4, the fixed edge 3 is fixedly connected to the base 1, so that a choke cavity 5 is formed between the composite leaflet 2 and the base 1, an inlet 6 of the choke cavity 5 is formed between the free edge 4 and the base 1, the free edge 4 can be freely switched between a first state and a second state under the action of intravascular pressure, the first state is a state when the free edge 4 moves close to the base 1 to close the inlet 6, and the second state is a state when the free edge 4 moves away from the base 1 to open the inlet 6; the composite leaflet 2 comprises a first leaflet 7 and a second leaflet 8 which are connected with each other, wherein two ends of a seam 9 formed by connecting the first leaflet 7 and the second leaflet 8 respectively extend to two connection points 10 of the fixed edge 3 and the free edge 4, the free edge 4 is positioned on the first leaflet 7, the fixed edge 3 is positioned on the second leaflet 8, and the thickness of the first leaflet 7 is smaller than that of the second leaflet 8.
The thickness of the first valve leaf 7 in the composite valve leaf 2 is set to be smaller than that of the second valve leaf 8, the first valve leaf 7 moves more flexibly, the valve can be opened or closed more easily, when blood flows through, the first valve leaf 7 can move more flexibly to the side of the base 1 under the action of blood flow, the valve can be opened more easily, so that blood flow can pass more easily, after the blood flows through the valve, when blood flows back, the first valve leaf 7 can move more flexibly away from the base 1 under the action of blood flow, so that the inlet 6 of the choke cavity 5 can be opened more easily, the blood flow flows into the choke cavity 5 to stop the blood flow, the functionality of the valve is improved, and the unidirectional circulation function of the valve is exerted more flexibly.
In some embodiments, the device further comprises a bracket, wherein the substrate 1 is fixedly attached to the inner wall of the bracket, and the bracket is used for being fixedly supported on the inner wall of the blood vessel. By the arrangement of the bracket, the implantation in the blood vessel is facilitated to position the valve.
In some embodiments, a base 1 is disposed on the inner wall of the stent, a composite leaflet 2 is disposed on the base 1, and when the free edge 4 is in the first state, there is an overflow gap between the composite leaflet 2 and the inner wall of the stent, and when the free edge 4 is in the second state, the free edge 4 is attached to the inner wall of the stent. Blood flows through the valve through the flow gap, and after flowing through the valve, the free edge 4 rapidly moves away from the base 1 and approaches the inner wall of the bracket on the other side, so that the inlet 6 of the choke cavity 5 is rapidly opened, and the blood is prevented from flowing back through the choke cavity 5.
In some embodiments, two substrates 1 are symmetrically arranged on the inner wall of the bracket, each substrate 1 is provided with a composite valve leaf 2, when the free edge 4 of each composite valve leaf 2 is in a first state, an overcurrent gap exists between the two composite valve leaves 2, when the free edge 4 of each composite valve leaf 2 is in a second state, the first valve leaves 7 of the two composite valve leaves 2 are mutually attached, and in the process of mutually attaching the first valve leaves 7 of the two composite valve leaves 2, most of blood flow can flow into the two choke cavities 5, so that the backflow prevention function of the composite valve leaves is exerted.
In some embodiments, the first leaflet 7 is made of a polymeric material and the second leaflet 8 is made of a biological material or a polymeric material. The first leaflet 7 having a thinner thickness can be manufactured using a polymer material, thereby improving the sensitivity of the response thereof.
In some embodiments, the polymeric material is a TPU material, but is not limited to a TPU material, and the biological material is bovine pericardium, but is not limited to bovine pericardium.
In some embodiments, the thickness of the first leaflet 7 is less than 0.3mm, and since the thickness of the valve made of bovine pericardium is difficult to be less than 0.3mm, the reaction sensitivity of the first leaflet 7 can be improved by setting the thickness of the first leaflet 7 to be less than 0.3mm, so that the unidirectional circulation function of the valve can be exerted more flexibly.
In some embodiments, the thickness of the first leaflet 7 is 0.02-0.2 mm, preferably 0.2mm.
In some embodiments, the first leaflet 7 is fixedly connected with the second leaflet 8 by stitching, and the first leaflet 7 is fixedly connected with the base 1 by stitching to facilitate the connection fixation.
The principles and embodiments of the present invention have been described in detail with reference to specific examples, which are provided to facilitate understanding of the method and core ideas of the present invention; also, it is within the scope of the present invention to be modified by those of ordinary skill in the art in light of the present teachings. In view of the foregoing, this description should not be construed as limiting the invention.
Claims (9)
1. A composite venous valve, characterized by: the device comprises a substrate and a composite valve blade, wherein one part of the edge of the composite valve blade is a fixed edge, the other part of the edge of the composite valve blade is a free edge, the fixed edge is fixedly connected to the substrate, a choke cavity is formed between the composite valve blade and the substrate, an inlet of the choke cavity is formed between the free edge and the substrate, the free edge can be freely switched between a first state and a second state under the action of intravascular pressure, the first state is a state when the free edge moves close to the substrate to close the inlet, and the second state is a state when the free edge moves away from the substrate to open the inlet; the composite leaflet comprises a first leaflet and a second leaflet which are connected with each other, wherein two ends of a seam formed by connecting the first leaflet and the second leaflet respectively extend to two connection points of the fixed edge and the free edge, the free edge is positioned on the first leaflet, the fixed edge is positioned on the second leaflet, and the thickness of the first leaflet is smaller than that of the second leaflet.
2. The composite venous valve of claim 1, wherein: the blood vessel support comprises a blood vessel inner wall, and is characterized by further comprising a support, wherein the substrate is fixedly attached to the support inner wall, and the support is used for being attached to and supported on the blood vessel inner wall.
3. The composite venous valve of claim 2, wherein: the novel composite valve is characterized in that one substrate is arranged on the inner wall of the support, one composite valve leaf is arranged on the substrate, when the free edge is in a first state, an overcurrent gap exists between the composite valve leaf and the inner wall of the support, and when the free edge is in a second state, the free edge is attached to the inner wall of the support.
4. The composite venous valve of claim 2, wherein: the inner wall of the support is symmetrically provided with two substrates, each substrate is provided with one composite valve leaf, when the free edge of each composite valve leaf is in a first state, an overcurrent gap exists between the two composite valve leaves, and when the free edge of each composite valve leaf is in a second state, the first valve leaves of the two composite valve leaves are mutually attached.
5. The composite venous valve of claim 1, wherein: the first valve leaflet is made of a high polymer material, and the second valve leaflet is made of a biological material or a high polymer material.
6. The composite venous valve of claim 5, wherein: the high polymer material is TPU material, and the biological material is bovine pericardium.
7. The composite venous valve of claim 1, wherein: the first leaflet has a thickness of less than 0.3mm.
8. The composite venous valve of claim 7, wherein: the thickness of the first valve leaflet is 0.02-0.2 mm.
9. The composite venous valve of claim 1, wherein: the first valve leaflet is fixedly connected with the second valve leaflet in a sewing mode, and the first valve leaflet is fixedly connected with the substrate in a sewing mode.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211222423.9A CN115444623B (en) | 2022-10-08 | 2022-10-08 | Composite venous valve |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211222423.9A CN115444623B (en) | 2022-10-08 | 2022-10-08 | Composite venous valve |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN115444623A CN115444623A (en) | 2022-12-09 |
| CN115444623B true CN115444623B (en) | 2023-08-04 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202211222423.9A Active CN115444623B (en) | 2022-10-08 | 2022-10-08 | Composite venous valve |
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| Country | Link |
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| CN (1) | CN115444623B (en) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105451688A (en) * | 2013-06-14 | 2016-03-30 | 哈祖有限公司 | Method and device for treatment of valve regurgitation |
| CN113878955A (en) * | 2021-09-27 | 2022-01-04 | 宁波健世科技股份有限公司 | Multilayer composite bionic polymer valve leaflet and manufacturing method thereof |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090105813A1 (en) * | 2007-10-17 | 2009-04-23 | Sean Chambers | Implantable valve device |
| WO2010011878A2 (en) * | 2008-07-24 | 2010-01-28 | Cook Incorporated | Valve device with biased leaflets |
| US8556960B2 (en) * | 2008-11-06 | 2013-10-15 | Cook Medical Technologies Llc | Frameless vascular valve |
| CN110353858A (en) * | 2018-04-09 | 2019-10-22 | 倍芮医疗器械（上海）有限公司 | For loading the bracket and venous valve displacement apparatus of valve |
| EP3905990A4 (en) * | 2019-01-03 | 2022-08-31 | Renovo Medsolutions, LLC | Venous valve prosthesis |
-
2022
- 2022-10-08 CN CN202211222423.9A patent/CN115444623B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105451688A (en) * | 2013-06-14 | 2016-03-30 | 哈祖有限公司 | Method and device for treatment of valve regurgitation |
| CN113878955A (en) * | 2021-09-27 | 2022-01-04 | 宁波健世科技股份有限公司 | Multilayer composite bionic polymer valve leaflet and manufacturing method thereof |
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| Publication number | Publication date |
|---|---|
| CN115444623A (en) | 2022-12-09 |
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