CN115444615A - Detachable intestinal tract stent - Google Patents
Detachable intestinal tract stent Download PDFInfo
- Publication number
- CN115444615A CN115444615A CN202211076655.8A CN202211076655A CN115444615A CN 115444615 A CN115444615 A CN 115444615A CN 202211076655 A CN202211076655 A CN 202211076655A CN 115444615 A CN115444615 A CN 115444615A
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- Prior art keywords
- degradable
- stent
- layer
- intestinal
- detachable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
- 210000001035 gastrointestinal tract Anatomy 0.000 title claims abstract description 10
- 239000003814 drug Substances 0.000 claims abstract description 24
- 239000011248 coating agent Substances 0.000 claims abstract description 7
- 238000000576 coating method Methods 0.000 claims abstract description 7
- 230000000968 intestinal effect Effects 0.000 claims description 34
- 229940079593 drug Drugs 0.000 claims description 7
- 102000008186 Collagen Human genes 0.000 claims description 5
- 108010035532 Collagen Proteins 0.000 claims description 5
- 229920001436 collagen Polymers 0.000 claims description 5
- 239000004809 Teflon Substances 0.000 claims description 3
- 229920006362 Teflon® Polymers 0.000 claims description 3
- 230000003115 biocidal effect Effects 0.000 claims description 3
- 235000010410 calcium alginate Nutrition 0.000 claims description 3
- 229960002681 calcium alginate Drugs 0.000 claims description 3
- 239000000648 calcium alginate Substances 0.000 claims description 3
- OKHHGHGGPDJQHR-YMOPUZKJSA-L calcium;(2s,3s,4s,5s,6r)-6-[(2r,3s,4r,5s,6r)-2-carboxy-6-[(2r,3s,4r,5s,6r)-2-carboxylato-4,5,6-trihydroxyoxan-3-yl]oxy-4,5-dihydroxyoxan-3-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylate Chemical compound [Ca+2].O[C@@H]1[C@H](O)[C@H](O)O[C@@H](C([O-])=O)[C@H]1O[C@H]1[C@@H](O)[C@@H](O)[C@H](O[C@H]2[C@H]([C@@H](O)[C@H](O)[C@H](O2)C([O-])=O)O)[C@H](C(O)=O)O1 OKHHGHGGPDJQHR-YMOPUZKJSA-L 0.000 claims description 3
- 229910001000 nickel titanium Inorganic materials 0.000 claims description 3
- 230000003110 anti-inflammatory effect Effects 0.000 claims description 2
- 230000001760 anti-analgesic effect Effects 0.000 claims 1
- HLXZNVUGXRDIFK-UHFFFAOYSA-N nickel titanium Chemical compound [Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni] HLXZNVUGXRDIFK-UHFFFAOYSA-N 0.000 claims 1
- 239000010410 layer Substances 0.000 description 38
- 206010061876 Obstruction Diseases 0.000 description 4
- 230000003211 malignant effect Effects 0.000 description 4
- 238000004804 winding Methods 0.000 description 4
- 239000011247 coating layer Substances 0.000 description 3
- HZEWFHLRYVTOIW-UHFFFAOYSA-N [Ti].[Ni] Chemical compound [Ti].[Ni] HZEWFHLRYVTOIW-UHFFFAOYSA-N 0.000 description 2
- 239000000956 alloy Substances 0.000 description 2
- 238000000338 in vitro Methods 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 229910001285 shape-memory alloy Inorganic materials 0.000 description 2
- 206010051268 Anastomotic stenosis Diseases 0.000 description 1
- 206010009944 Colon cancer Diseases 0.000 description 1
- 208000001333 Colorectal Neoplasms Diseases 0.000 description 1
- 208000005189 Embolism Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 206010022699 Intestinal stenosis Diseases 0.000 description 1
- 208000031481 Pathologic Constriction Diseases 0.000 description 1
- 210000001015 abdomen Anatomy 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 210000001072 colon Anatomy 0.000 description 1
- 230000006835 compression Effects 0.000 description 1
- 238000007906 compression Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000003467 diminishing effect Effects 0.000 description 1
- 230000002183 duodenal effect Effects 0.000 description 1
- 238000002513 implantation Methods 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 208000003243 intestinal obstruction Diseases 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 230000009545 invasion Effects 0.000 description 1
- 238000002357 laparoscopic surgery Methods 0.000 description 1
- 238000002350 laparotomy Methods 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000002638 palliative care Methods 0.000 description 1
- 210000000664 rectum Anatomy 0.000 description 1
- 210000000813 small intestine Anatomy 0.000 description 1
- 230000036262 stenosis Effects 0.000 description 1
- 208000037804 stenosis Diseases 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/0077—Special surfaces of prostheses, e.g. for improving ingrowth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2210/0004—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof bioabsorbable
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
- A61F2250/0067—Means for introducing or releasing pharmaceutical products into the body
Landscapes
- Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Pulmonology (AREA)
- Materials For Medical Uses (AREA)
Abstract
The invention discloses a detachable intestinal tract stent which comprises a stent body, wherein bosses are arranged on annular edges at two ends of the stent body, the stent body comprises a plurality of stent meshes, each stent mesh is arranged in an arc sheet shape, a plurality of stent meshes are wound and bolted together at two opposite sides in the transverse direction through a first degradable line, a plurality of stent meshes are wound and bolted together at two opposite sides in the longitudinal direction through a second degradable line, and a medicine coating device is arranged on the outer side wall of the stent body. The stent body is quickly decomposed into a plurality of stent meshes through the first degradable line and the second degradable line which are meltable, and then the single stent mesh is easier to be discharged out of the body, so that the stent is prevented from being taken out by using special instruments or performing operations, the convenience is improved, and the practicability is high.
Description
Technical Field
The invention relates to the technical field of intestinal stents, in particular to a detachable intestinal stent.
Background
In recent years, reports of treating colorectal malignant obstruction by using various metal stents as intestinal lumen internal supports at home and abroad are gradually increased, namely, a reticular stent is placed at a narrow part of an intestinal tract to open the intestinal tract, so that the narrow or blocked part is recovered to be unobstructed again, the colorectal malignant obstruction can be used for permanent or temporary treatment of colorectal cancer malignant obstruction, and conditions are created for phase-selective operations. The intestinal stent is suitable for patients with duodenal, small intestine, colon and rectum stenosis obstruction and anastomotic stenosis caused by invasion, compression or other malignant lesions of advanced malignant tumors of the abdomen.
Intestinal stent implantation has been increasingly used as a non-operative palliative treatment for intestinal stenosis patients or intestinal obstruction patients, in the prior art, after being implanted for a period of time, a special instrument is needed to be used for taking out the intestinal stent, even a surgical laparotomy or laparoscopic surgery is needed to be carried out, the section of intestine containing the stent is cut off to achieve the purpose of taking out the stent, and then the stent is complex in detachment process and inconvenient.
Disclosure of Invention
The present invention provides a detachable intestinal stent to solve the problems of the background art as set forth above.
In order to achieve the purpose, the invention adopts the following technical scheme:
the detachable intestinal tract stent comprises a stent body, wherein bosses are arranged on annular edges at two ends of the stent body, the stent body comprises a plurality of stent meshes, each stent mesh is in an arc-shaped sheet shape and is in a plurality of winding and bolting together through a first degradable line on one side of each transverse pair of opposite sides of each stent mesh, the stent meshes are in a plurality of winding and bolting together through a second degradable line on one side of each longitudinal pair of opposite sides of each stent mesh, and a medicine coating device is arranged on the outer side wall of the stent body.
As a further improvement scheme of the technical scheme: the medicine coating device comprises a second degradable layer, a medicine coating layer and a first degradable layer, wherein the second degradable layer is positioned on the surface of the bracket body, the medicine coating layer is positioned on the surface of the second degradable layer, and the first degradable layer is positioned on the surface of the medicine coating layer.
As a further improvement scheme of the technical scheme: the inner side of the bracket body is provided with a smooth layer.
As a further improvement scheme of the technical scheme: the first degradable line and the second degradable line are both degradable collagen lines.
As a further improvement scheme of the technical scheme: and each stent mesh is made of a nickel-titanium shape memory alloy material.
As a further improvement scheme of the technical scheme: the smooth layer adopts the Teflon coating, and the thickness of the smooth layer is 0.3-0.8 mm.
As a further improvement scheme of the technical scheme: first degradable layer and second degradable layer all adopt easily to be made by the calcium alginate material that the intestinal dissolves, the thickness on first degradable layer and second degradable layer is 0.5-1 millimeter.
As a further improvement scheme of the technical scheme: the medicine applying layer adopts antibiotic medicines for diminishing inflammation and relieving pain of intestinal tracts.
As a further improvement scheme of the technical scheme: the thickness of the support net sheet is 0.5-1 mm.
Compared with the prior art, the invention has the beneficial effects that:
the support body is fixed together through the winding of horizontal first degradable line and fore-and-aft second degradable line by a plurality of support net pieces, and then form tubulose support form, after putting into patient's intestinal with tubulose support body, the support body will laminate on intestinal lateral wall, the first degradable layer in the support body outside will be dissolved by the intestinal fast, and then make the lateral wall contact of applying medicine layer and intestinal, when the support body is located about one month in the intestinal, adopt collagen line's first degradable line and second degradable line will dissolve, and then the support body will form a plurality of tiny support net pieces, the support net piece can be discharged along with the intestinal excrement again in vitro, and then reach the mesh of automatic demolising the support body, the device reasonable in design, the design is ingenious, decompose the support body into a plurality of support net pieces through the first degradable line of fusibility and second degradable line, later the independent support is discharged outside more easily again, avoided using special apparatus or taking out the support in operation, the convenience has been increased, and the practicality is high.
The foregoing description is only an overview of the technical solutions of the present invention, and in order to make the technical solutions of the present invention more clearly understood and to implement them in accordance with the contents of the description, the following detailed description is given with reference to the preferred embodiments of the present invention and the accompanying drawings. The detailed description of the present invention is given in detail by the following examples and the accompanying drawings.
Drawings
The accompanying drawings, which are included to provide a further understanding of the invention and are incorporated in and constitute a part of this application, illustrate embodiment(s) of the invention and together with the description serve to explain the invention without limiting the invention. In the drawings:
fig. 1 is a schematic structural view of a detachable intestinal stent proposed by the present invention;
fig. 2 is a side sectional view schematically illustrating a detachable intestinal stent according to the present invention;
fig. 3 is a schematic perspective view of a stent mesh in a detachable intestinal stent according to the present invention;
fig. 4 is a partially enlarged structural diagram of a in fig. 2.
In the drawings, the components represented by the respective reference numerals are listed below:
1 first degradable layer, 2 apply medicine layer, 3 second degradable layers, 4 smooth layers, 5 first degradable lines, 6 support net pieces, 7 bosss, 8 second degradable lines, 9 support bodies.
Detailed Description
The principles and features of this invention are described below in conjunction with the following drawings, which are set forth by way of illustration only and are not intended to limit the scope of the invention. The invention is described in more detail in the following paragraphs by way of example with reference to the accompanying drawings. Advantages and features of the present invention will become apparent from the following description and from the claims. It is to be noted that the drawings are in a very simplified form and are not to precise scale, which is merely for the purpose of facilitating and distinctly claiming the embodiments of the present invention.
It will be understood that when an element is referred to as being "secured to" another element, it can be directly on the other element or intervening elements may also be present. When a component is referred to as being "connected" to another component, it can be directly connected to the other component or intervening components may also be present. When a component is referred to as being "disposed on" another component, it can be directly on the other component or intervening components may also be present. The terms "vertical," "horizontal," "left," "right," and the like as used herein are for illustrative purposes only.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. The terminology used in the description of the invention herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. As used herein, the term "and/or" includes any and all combinations of one or more of the associated listed items.
Referring to fig. 1 to 4, in the embodiment of the present invention, the detachable intestinal stent includes a stent body 9, bosses 7 are disposed on annular edges of two ends of the stent body 9, the stent body 9 includes a plurality of stent meshes 6, each stent mesh 6 is disposed in an arc sheet shape, two opposite sides of the plurality of stent meshes 6 in a transverse direction are wound and bolted together through a first degradable line 5, two opposite sides of the plurality of stent meshes 6 in a longitudinal direction are wound and bolted together through a second degradable line 8, and a drug coating device is disposed on an outer side wall of the stent body 9.
Specifically, scribble the medicine device and include second degradable layer 3, apply medicine layer 2 and first degradable layer 1, second degradable layer 3 is located support body 9 on the surface, apply medicine layer 2 and be located second degradable layer 3 on the surface, first degradable layer 1 is located and applies medicine layer 2 on the surface, first degradable layer 1 and second degradable layer 3 all adopt easily to be made by the calcium alginate material that the intestinal dissolved, the thickness of first degradable layer 1 and second degradable layer 3 is 0.5-1 millimeter, apply medicine layer 2 and adopt the analgesic antibiotic medicine of intestinal anti-inflammatory.
Specifically, the inner side of the stent body 9 is provided with a smooth layer 4, the smooth layer 4 is a Teflon coating, the thickness of the smooth layer 4 is 0.3-0.8 mm, and the smooth layer 4 can further smooth the inner cavity of the stent body 9, thereby facilitating the smooth passing of contents and avoiding the generation of embolus.
Specifically, the first degradable thread 5 and the second degradable thread 8 are both degradable collagen threads.
Specifically, each stent mesh 6 is made of a nickel titanium shape memory alloy material.
Specifically, the thickness of the stent mesh 6 is 0.5 to 1 mm.
The working principle of the invention is as follows:
the support body 9 is fixed together through the winding of horizontal first degradable line 5 and fore-and-aft second degradable line 8 by a plurality of support net pieces 6, and then form the tubulose support form, after putting into patient's intestinal with tubulose support body 9, support body 9 will laminate on the lateral wall of intestinal, the first degradable layer 1 in the support body 9 outside will be dissolved by the intestinal fast, and then make and apply medicine layer 2 and the lateral wall contact of intestinal, when support body 9 is located about one month in the intestinal, the first degradable line 5 and the second degradable line 8 that adopt the collagen line will dissolve, and then support body 9 will form a plurality of tiny support net pieces 6, support net piece 6 can be discharged along with the intestinal excrement again in vitro, and then reach the automatic mesh of demolising support body 9.
The foregoing is merely a preferred embodiment of the invention and is not intended to limit the invention in any manner; one of ordinary skill in the art will readily appreciate from the disclosure that the present invention can be practiced as illustrated in the accompanying drawings and described above; however, those skilled in the art should appreciate that they can readily use the disclosed conception and specific embodiments as a basis for designing or modifying other structures for carrying out the same purposes of the present invention without departing from the scope of the invention as defined by the appended claims; meanwhile, any changes, modifications, and evolutions of the equivalent changes of the above embodiments according to the actual techniques of the present invention are still within the protection scope of the technical solution of the present invention.
Claims (9)
1. The detachable intestinal tract bracket comprises a bracket body (9) and is characterized in that bosses (7) are arranged on annular edges at two ends of the bracket body (9), the bracket body (9) comprises a plurality of bracket net pieces (6), each bracket net piece (6) is in an arc-shaped sheet shape, a plurality of bracket net pieces (6) are transversely wound and bolted together on two opposite sides through a first degradable line (5), a plurality of bracket net pieces (6) are longitudinally wound and bolted together on two opposite sides through a second degradable line (8), and a medicine coating device is arranged on the outer side wall of the bracket body (9).
2. Removable intestinal stent according to claim 1, wherein the drug application means comprises a second degradable layer (3), a drug application layer (2) and a first degradable layer (1), the second degradable layer (3) being located on the surface of the stent body (9), the drug application layer (2) being located on the surface of the second degradable layer (3), the first degradable layer (1) being located on the surface of the drug application layer (2).
3. Removable intestinal stent according to claim 1, wherein the inside of the stent body (9) is provided with a lubricious layer (4).
4. The detachable intestinal stent according to claim 1, wherein the first degradable thread (5) and the second degradable thread (8) are both degradable collagen threads.
5. Detachable intestinal stent according to claim 1, wherein each of said stent meshes (6) is made of nitinol.
6. Removable intestinal stent according to claim 3, wherein the lubricious layer (4) is Teflon coated and the thickness of the lubricious layer (4) is 0.3-0.8 mm.
7. The detachable intestinal stent according to claim 2, wherein the first degradable layer (1) and the second degradable layer (3) are made of calcium alginate which is easily dissolved by intestinal tract, and the thickness of the first degradable layer (1) and the second degradable layer (3) is 0.5-1 mm.
8. Removable intestinal stand according to claim 2, characterized in that said medicated layer (2) uses antibiotic drugs for anti-inflammatory and analgesic intestinal tract.
9. Removable intestinal stent according to claim 1, wherein the thickness of the stent mesh (6) is 0.5-1 mm.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211076655.8A CN115444615A (en) | 2022-09-05 | 2022-09-05 | Detachable intestinal tract stent |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211076655.8A CN115444615A (en) | 2022-09-05 | 2022-09-05 | Detachable intestinal tract stent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN115444615A true CN115444615A (en) | 2022-12-09 |
Family
ID=84300214
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202211076655.8A Pending CN115444615A (en) | 2022-09-05 | 2022-09-05 | Detachable intestinal tract stent |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN115444615A (en) |
-
2022
- 2022-09-05 CN CN202211076655.8A patent/CN115444615A/en active Pending
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