CN115429215A - Intraocular OCT optical fiber probe - Google Patents

Intraocular OCT optical fiber probe Download PDF

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Publication number
CN115429215A
CN115429215A CN202211395260.4A CN202211395260A CN115429215A CN 115429215 A CN115429215 A CN 115429215A CN 202211395260 A CN202211395260 A CN 202211395260A CN 115429215 A CN115429215 A CN 115429215A
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fiber
oct
optical fiber
intraocular
metal sleeve
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CN202211395260.4A
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CN115429215B (en
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张弛
陈雀敏
张冰莹
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Beijing Xiran Technology Co ltd
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Beijing Xiran Technology Co ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/102—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for optical coherence tomography [OCT]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/0008—Apparatus for testing the eyes; Instruments for examining the eyes provided with illuminating means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/12—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for looking at the eye fundus, e.g. ophthalmoscopes
    • A61B3/1225—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for looking at the eye fundus, e.g. ophthalmoscopes using coherent radiation

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Physics & Mathematics (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Eye Examination Apparatus (AREA)

Abstract

The invention relates to an intraocular OCT fiber probe, the intraocular OCT fiber probe includes OCT optic fibre, optic fibre metal sleeve, photoconductive fiber, rotating motor and hand grip outer casing, the head ends of OCT optic fibre and photoconductive fiber are fixedly encapsulated in the inside of the metal sleeve of optic fibre; the optical fiber metal sleeve is also connected with a rotating motor, the rotating motor drives the optical fiber metal sleeve to rotate, and the optical fiber metal sleeve drives the head ends of the OCT optical fiber and the photoconductive optical fiber to rotate; the rotary motor is electrically connected with a power line, and the power line provides power for the rotary motor; at least one part of the optical fiber metal sleeve and the rotating motor are arranged in the handle shell; the tail end of the light guide optical fiber penetrates out of the end part of the handle shell and is connected with the illumination light source, and the light guide optical fiber is used for providing illumination; the tail end of the OCT optical fiber penetrates out of the end part of the handle shell and is connected with OCT inspection equipment, and the OCT optical fiber is used for carrying out intraocular invasive OCT inspection.

Description

Intraocular OCT optical fiber probe
Technical Field
The invention relates to the technical field of medical instruments, in particular to an intraocular OCT fiber probe.
Background
OCT (optical coherence tomography) is a medical imaging approach based on low coherence interference. The OCT imaging system is widely used in ophthalmology and cardiology, where ophthalmology is currently an outpatient examination device used for imaging structures of the eye such as the retina before and after surgery.
The OCT has the working principle that different tissues in the eye have different reflectivities to light (using 830nm near infrared light), the structures and the distances of the different tissues are analyzed by comparing the delay time and the reflection intensity of the reflected light wave and the reference light wave through a low-coherence light interferometer, and the structures and the distances of the different tissues are processed and imaged by a computer, and the section structures of the tissues are displayed in a pseudo-color mode. Therefore, OCT requires a swinging mirror, so that the OCT in the prior art is mostly in a table structure.
That is, the conventional ophthalmic OCT is a table-type examination device, which is generally equipped in an examination room for use in quantifying the pathological condition in the eye before surgery and in post-operative review. The current application in surgery is to integrate OCT into a microscope to facilitate scanning of the retina during surgery and to assess the treatment of intraocular pathologies during surgery. The non-invasive examination is affected by refractive interstitial substance in measurement, and the imaging quality is affected.
At present, invasive OCT is mainly applied to cardiology department and adherence examination of coronary stents. The ophthalmological invasive examination has not been a good solution in the field due to the small operating space, the difficulty of illumination and the poor control of the scanning direction.
Disclosure of Invention
The invention aims to provide an intraocular OCT fiber probe, and the technical problems to be solved at least include how to apply invasive OCT examination to ophthalmology, so that OCT in operation is not influenced by refraction light interstitials during scanning, illumination is convenient, the scanning direction is artificially controllable, and positioning is more accurate and convenient.
In order to achieve the purpose, the invention provides an intraocular OCT fiber probe, which comprises an OCT fiber, a fiber metal sleeve, a light guide fiber, a rotary motor and a handle shell, wherein the head ends of the OCT fiber and the light guide fiber are fixedly packaged in the fiber metal sleeve; the optical fiber metal sleeve is also connected with a rotating motor, the rotating motor drives the optical fiber metal sleeve to rotate, and the optical fiber metal sleeve drives the head ends of the OCT optical fiber and the photoconductive optical fiber to rotate; the rotary motor is electrically connected with a power line, and the power line supplies power to the rotary motor; at least one part of the optical fiber metal sleeve and the rotating motor are arranged in the handle shell; the tail end of the light guide optical fiber penetrates out of the end part of the handle shell and is connected with an illumination light source, and the light guide optical fiber is used for providing illumination; the tail end of the OCT optical fiber penetrates out of the end part of the handle shell and is connected with OCT inspection equipment, and the OCT optical fiber is used for carrying out intraocular invasive OCT inspection.
Preferably, the gap between the head ends of the OCT optical fiber and the inner wall of the optical fiber metal sleeve is filled with AB glue.
Preferably, the rotating motor drives the fiber metal sleeve to rotate, rather than rotating the optical fiber.
In a preferred embodiment, the light guide fiber is a multimode fiber.
In another preferred embodiment, the light guide fiber is a single mode fiber.
Preferably, the rotation of the fiber metal sleeve is such that the scan rotation angle of the intraocular OCT optical fiber is 1 ° to 360 °.
Preferably, the OCT optical fiber comprises a single-mode optical fiber, a spring tube, a glass rod, a self-focusing lens and a reflector, wherein the single-mode optical fiber is sleeved in the spring tube; one end of the glass rod is glued with the zero-degree angle surface of the self-focusing lens, the other end of the glass rod is obliquely glued with the single-mode optical fiber, the working distance of the OCT probe can be changed by changing the gluing distance between the glass rod and the single-mode optical fiber so as to achieve the working distance required by expectation, and further the numerical aperture and the transverse resolution of the OCT probe are improved; the single-mode optical fiber, the spring tube, the glass rod, the self-focusing lens and the reflector are packaged in the optical fiber metal sleeve, and the reflector is used for reducing the influence of astigmatism of a light source passing through the cylindrical inner tube of the optical fiber metal sleeve on imaging.
Preferably, the fiber metal sleeve is a slotted stainless steel tube, a slot is arranged on a side wall of the fiber metal sleeve, and a reflecting surface of the reflector faces the slotted opening of the slot, so as to reduce the influence of astigmatism of a light source passing through the cylindrical inner tube of the fiber metal sleeve on imaging.
Preferably, the reflector is a cylindrical reflector.
Preferably, the end of the fiber metal sleeve is sealed with UV glue.
Advantageous effects
Compared with the prior art, the invention has the beneficial effects that:
the OCT optical fiber probe provided by the invention is used for intraocular examination, can be integrated with the light guide optical fiber, can be used for OCT examination while adopting conventional illumination, and is not influenced by refraction light interstitials during OCT scanning in an operation.
The intraocular OCT optical fiber changes the working distance of the OCT probe by changing the gluing distance between the glass rod 3 and the single-mode optical fiber 1 so as to achieve the expected required working distance, thereby improving the numerical aperture and the transverse resolution of the OCT probe; by orienting the reflecting surface of the reflector 5 towards the slotted opening of the slotted stainless steel tube 6, the influence of the astigmatism of the light source through the cylindrical inner tube on the imaging can be reduced.
Drawings
The accompanying drawings are included to provide a further understanding of the invention and are incorporated in and constitute a part of this specification, illustrate embodiments of the invention and together with the description serve to explain the principles of the invention and not to limit the invention.
Fig. 1 is a schematic view of the internal structure of an intraocular OCT optical fiber according to the present invention.
Fig. 2 is a schematic view of the overall structure of the intraocular OCT optical fiber according to the present invention.
Figure 3 is a schematic structural view of one embodiment of the intraocular OCT optical fiber.
Figure 4 is a schematic structural view of another embodiment of the intraocular OCT optical fiber.
Detailed Description
The present invention is described in more detail below to facilitate an understanding of the present invention.
As shown in fig. 1 and fig. 2, the intraocular OCT optical fiber of the present invention includes an OCT optical fiber 30, an optical fiber metal sleeve 6, a light guide optical fiber 8, a rotation motor 9, and a handle housing 10, wherein the head ends of the OCT optical fiber 30 and the light guide optical fiber 8 are fixedly packaged inside the optical fiber metal sleeve 6; the optical fiber metal sleeve 6 is further connected with a rotating motor 9, the rotating motor 9 drives the optical fiber metal sleeve 6 to rotate, and the optical fiber metal sleeve 6 drives the head ends of the OCT optical fiber 30 and the optical guide fiber 8 to rotate; the rotary motor 9 is electrically connected with a power line 11, and the power line 11 supplies power to the rotary motor 9; at least one part of the optical fiber metal sleeve 6 and the rotating motor 9 are arranged in the handle shell 10; the tail end of the light guide optical fiber 8 penetrates out of the end of the handle shell 10 and is connected with an illumination light source, and the light guide optical fiber 8 is used for providing illumination; the tail end of the OCT optical fiber 30 penetrates out of the end part of the handle shell 10 and is connected with an OCT inspection device, and the OCT optical fiber 30 is used for carrying out intraocular invasive OCT inspection.
Preferably, the gap between the head ends of the OCT optical fiber 30 and the optical fiber 8 and the inner wall of the optical fiber metal sleeve 6 is filled with AB glue.
In this application, the fiber metal ferrule 6 is driven to rotate by the rotation motor 9, instead of rotating the optical fiber. The advantage of this arrangement is that rotating the fiber optic ferrule makes the entire intraocular OCT fiber more stable, thereby ensuring that OCT inspection is more accurate. And the direct rotation of the optical fiber can cause the optical fiber to shake violently, which affects the accuracy of the OCT test.
In a preferred embodiment, the light guide fiber 8 is a multimode fiber.
In another preferred embodiment, the light guide fiber 8 is a single mode fiber.
Preferably, the rotation of the fiber metal sleeve 6 is such that the scan rotation angle of the intraocular OCT optical fiber is 1 ° to 360 °.
The schematic diagram shown in fig. 2 is for illustrative purposes only, and those skilled in the art can fully understand that the head end and the tail end of the OCT optical fiber 30 are connected to each other by a single optical fiber, and the head end and the tail end of the optical fiber 8 are also connected to each other by a single optical fiber.
Preferably, the OCT optical fiber 30 includes a single-mode optical fiber 1, a spring tube 2, a glass rod 3, a self-focusing lens 4 and a mirror 5, wherein the single-mode optical fiber 1 is sleeved in the spring tube 2; one end of the glass rod 3 is glued with the zero-degree angle surface of the self-focusing lens 4, the other end of the glass rod 3 is obliquely glued with the single-mode optical fiber 1, the working distance of the OCT probe can be changed by changing the gluing distance between the glass rod 3 and the single-mode optical fiber 1 so as to reach the expected required working distance, and further the numerical aperture and the transverse resolution of the OCT probe are improved; the single-mode optical fiber 1, the spring tube 2, the glass rod 3, the self-focusing lens 4 and the reflector 5 are packaged in the optical fiber metal sleeve 6, and the reflector 5 is used for reducing the influence of light source astigmatism of the cylindrical inner tube of the optical fiber metal sleeve 6 on imaging.
Preferably, the fiber metal sleeve 6 is a slotted stainless steel tube, a slot 40 is disposed on a side wall of the fiber metal sleeve 6, and a reflecting surface of the reflector 5 faces a slotted opening of the slot 40, so as to reduce an influence of astigmatism of a light source passing through a cylindrical inner tube of the fiber metal sleeve 6 on imaging.
Preferably, the reflector 5 is a cylindrical reflector, and at least one reflecting surface of the reflector forms an included angle different from 90 degrees with the optical fiber.
Preferably, the end of the fiber metal ferrule 6 is closed with UV glue 20.
The bourdon tube 2 is used to protect the single mode optical fiber 1.
The intraocular OCT optical fiber can be applied to ophthalmology, is not influenced by bent light interstitium during OCT scanning in operation, has manually controllable scanning direction and more accurate and convenient positioning, and can confirm whether an operation target is realized or not in the operation without postoperative confirmation.
The rotating motor in the invention drives the optical fiber metal sleeve 6 to rotate, but not the optical fiber, and the scanning rotation angle is 1-360 degrees.
In the prior art, the OCT is integrated in a microscope, and when the ophthalmic OCT is performed, the OCT optical fiber does not directly contact the eye (the eye includes structures such as a cornea, a crystal, aqueous humor and the like), the cornea needs to be scanned first, then the aqueous humor needs to be scanned, and the OCT probe in the application directly penetrates into the eye to scan the retina, so that the OCT probe is not affected by refractive light interstitials.
In the embodiment shown in fig. 3, the intraocular OCT optical fiber according to the present invention further includes a sliding rod 12 and a connecting rod 16, one end of the sliding rod 12 is fixedly disposed on the outer circumferential wall of the handpiece housing 10; the other end of the slide bar 12 extends obliquely upward in a direction away from the handle housing 10; one end of the connecting rod 16 is connected with the sliding rod 12, the other end of the connecting rod 16 is connected with the optical fiber fixing shaft, and the optical fiber fixing shaft is driven to move back and forth through the connecting rod 16 by pressing the sliding rod 12, so that the length of the optical fiber 14 is adjusted.
In a preferred embodiment, the fiber securing shaft is the rotation motor 9.
The end part of the rotary motor 9 close to the optical fiber metal sleeve 6 is also provided with a spring 13.
The part of the optical fiber 14 at one side of the optical fiber fixing shaft is also provided with a spiral structure.
The number of the spiral structures is zero or more.
The optical fiber 14 includes an OCT optical fiber 30 and a light guide optical fiber 8.
By pressing the sliding rod 12, the rotating motor 9 can be driven to move back and forth through the connecting rod 16, the rotating motor 9 can drive the optical fiber 14 and the optical fiber metal sleeve 6 to move back and forth, and further the OCT optical fiber is telescopic, so that a doctor can conveniently adjust the working distance of the OCT optical fiber in eyes.
In the embodiment shown in fig. 4, the intraocular OCT optical fiber of the present invention further includes a push rod 15, the outer peripheral wall of the handle housing 10 is provided with a sliding groove for the push rod 15 to move forward and backward, the push rod 15 is inserted into the sliding groove, and one end of the push rod 15 located inside the handle housing 10 is connected to the rotation motor 9.
By moving the push rod 15 back and forth along the direction of the bidirectional arrow in fig. 4, the rotary motor 9 can be driven to move back and forth, and the rotary motor 9 can drive the optical fiber 14 and the optical fiber metal sleeve 6 to move back and forth, so that the optical fiber can be stretched and retracted, and a doctor can conveniently adjust the working distance of the optical fiber in the eye.
The part of the optical fiber 14 at one side of the optical fiber fixing shaft is also provided with a spiral structure.
The number of the spiral structures is zero or more.
The optical fiber 14 includes an OCT optical fiber 30 and a light guide optical fiber 8.
The technical key points of the application at least comprise:
1. the application applies OCT fiber to ophthalmology.
2. In this application, the rotating motor drives the fiber metal ferrule to rotate, rather than the optical fiber.
3. The scanning rotation angle of the present application is 1 ° to 360 °.
4. The OCT optical fiber and the light guide optical fiber are combined together, and the problem of illumination is solved.
5. The application realizes that the OCT optical fiber probe is telescopic.
The above description is of the preferred embodiment of the present invention, but it is not intended to limit the present invention. Modifications and variations of the embodiments disclosed herein may be made by those skilled in the art without departing from the scope and spirit of the invention.

Claims (10)

1. An intraocular OCT fiber optic probe is characterized by comprising an OCT fiber, a fiber metal sleeve, a light guide fiber, a rotary motor and a handle shell, wherein the head ends of the OCT fiber and the light guide fiber are fixedly packaged in the fiber metal sleeve; the optical fiber metal sleeve is also connected with a rotating motor, the rotating motor drives the optical fiber metal sleeve to rotate, and the optical fiber metal sleeve drives the head ends of the OCT optical fiber and the photoconductive optical fiber to rotate; the rotary motor is electrically connected with a power line, and the power line supplies power to the rotary motor; at least one part of the optical fiber metal sleeve and the rotating motor are arranged in the handle shell; the tail end of the light guide optical fiber penetrates out of the end part of the handle shell and is connected with an illumination light source, and the light guide optical fiber is used for providing illumination; the tail end of the OCT optical fiber penetrates out of the end part of the handle shell and is connected with OCT inspection equipment, and the OCT optical fiber is used for carrying out intraocular invasive OCT inspection.
2. The intraocular OCT fiber optic probe of claim 1, wherein a gap between the leading ends of said OCT fiber and light guide fiber and the inner wall of said fiber optic metal sleeve is filled with an adhesive.
3. The intraocular OCT fiber optic probe of claim 1, wherein said rotation motor drives said fiber optic metal ferrule to rotate without directly rotating the fiber.
4. The intraocular OCT optical fiber probe of claim 1, wherein said light guide fiber is a multimode fiber.
5. The intraocular OCT optical fiber probe of claim 1, wherein said light guide fiber is a single mode fiber.
6. The intraocular OCT fiber optic probe of claim 1, wherein rotation of the fiber optic metal cannula causes a scan rotation angle of the intraocular OCT fiber to be 1 ° to 360 °.
7. The intraocular OCT fiber optic probe of claim 1, wherein said OCT fiber comprises a single mode fiber, a pogo-tube, a glass rod, a self-focusing lens, and a mirror, said single mode fiber being nested in the pogo-tube; one end of the glass rod is glued with the zero-degree angle surface of the self-focusing lens, and the other end of the glass rod is obliquely glued with the single-mode optical fiber; the single-mode optical fiber, the spring tube, the glass rod, the self-focusing lens and the reflector are packaged in the optical fiber metal sleeve, and at least one reflecting surface of the reflector and the optical fiber form an included angle which is not 90 degrees.
8. The intraocular OCT optical fiber probe of claim 7, wherein the fiber metal sleeve is a slotted stainless steel tube, and a slot is disposed on a sidewall of the fiber metal sleeve, and a reflective surface of the mirror faces the slotted opening of the slot for reducing an influence of light scattered from the light source through the cylindrical inner tube of the fiber metal sleeve.
9. The intraocular OCT fiber optic probe of claim 7, wherein said mirror is a cylindrical mirror.
10. The intraocular OCT fiber optic probe of claim 1, wherein an end of the fiber metal cannula is sealed with UV glue.
CN202211395260.4A 2022-11-09 2022-11-09 Intraocular OCT optical fiber probe Active CN115429215B (en)

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Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012166116A1 (en) * 2011-05-31 2012-12-06 Vanderbilt University Optical coherence tomography probe
US20120310042A1 (en) * 2011-05-31 2012-12-06 Karen Joos Apparatus and method for real-time imaging and monitoring of an electrosurgical procedure
JP2013141499A (en) * 2012-01-10 2013-07-22 Sun Tec Kk Imaging probe
CN104825121A (en) * 2015-05-08 2015-08-12 南京微创医学科技有限公司 Endoscopic OCT (Optical Coherence Tomography) miniature probe, OCT imaging system and use method
CN105286800A (en) * 2015-11-25 2016-02-03 深圳大学 Mechanically rotating intravascular OCT (optical coherence tomography) imaging probe
CN109124588A (en) * 2018-09-25 2019-01-04 南开大学 A kind of OCT probe for mouth disease inspection
CN110881942A (en) * 2019-12-11 2020-03-17 上海交通大学 OCT-based bimodal optical fiber endoscope device
CN114847866A (en) * 2022-03-30 2022-08-05 图湃(北京)医疗科技有限公司 Side OCT imaging miniature optical fiber endoscope probe and manufacturing method thereof

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012166116A1 (en) * 2011-05-31 2012-12-06 Vanderbilt University Optical coherence tomography probe
US20120310042A1 (en) * 2011-05-31 2012-12-06 Karen Joos Apparatus and method for real-time imaging and monitoring of an electrosurgical procedure
JP2013141499A (en) * 2012-01-10 2013-07-22 Sun Tec Kk Imaging probe
CN104825121A (en) * 2015-05-08 2015-08-12 南京微创医学科技有限公司 Endoscopic OCT (Optical Coherence Tomography) miniature probe, OCT imaging system and use method
CN105286800A (en) * 2015-11-25 2016-02-03 深圳大学 Mechanically rotating intravascular OCT (optical coherence tomography) imaging probe
CN109124588A (en) * 2018-09-25 2019-01-04 南开大学 A kind of OCT probe for mouth disease inspection
CN110881942A (en) * 2019-12-11 2020-03-17 上海交通大学 OCT-based bimodal optical fiber endoscope device
CN114847866A (en) * 2022-03-30 2022-08-05 图湃(北京)医疗科技有限公司 Side OCT imaging miniature optical fiber endoscope probe and manufacturing method thereof

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