CN115414576B - Balloon Catheter Structure - Google Patents
Balloon Catheter Structure Download PDFInfo
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- CN115414576B CN115414576B CN202210994551.9A CN202210994551A CN115414576B CN 115414576 B CN115414576 B CN 115414576B CN 202210994551 A CN202210994551 A CN 202210994551A CN 115414576 B CN115414576 B CN 115414576B
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- sleeve
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- balloon catheter
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- open hole
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- 239000003814 drug Substances 0.000 claims abstract description 61
- 229940079593 drug Drugs 0.000 claims abstract description 53
- 238000000576 coating method Methods 0.000 claims description 26
- 239000011248 coating agent Substances 0.000 claims description 25
- 238000004891 communication Methods 0.000 claims description 9
- 239000003504 photosensitizing agent Substances 0.000 claims description 8
- 238000004804 winding Methods 0.000 claims description 6
- -1 polytetrafluoroethylene Polymers 0.000 claims description 4
- 229920001343 polytetrafluoroethylene Polymers 0.000 claims description 4
- 239000004810 polytetrafluoroethylene Substances 0.000 claims description 4
- 238000000034 method Methods 0.000 abstract description 12
- 230000008569 process Effects 0.000 abstract description 10
- 230000003902 lesion Effects 0.000 description 27
- 210000004204 blood vessel Anatomy 0.000 description 15
- 230000017531 blood circulation Effects 0.000 description 5
- 230000002792 vascular Effects 0.000 description 5
- 239000008280 blood Substances 0.000 description 4
- 210000004369 blood Anatomy 0.000 description 4
- 230000003014 reinforcing effect Effects 0.000 description 3
- 238000009991 scouring Methods 0.000 description 3
- 230000007704 transition Effects 0.000 description 3
- 230000000903 blocking effect Effects 0.000 description 2
- 238000011010 flushing procedure Methods 0.000 description 2
- 238000005286 illumination Methods 0.000 description 2
- 230000002503 metabolic effect Effects 0.000 description 2
- 230000001681 protective effect Effects 0.000 description 2
- 208000037803 restenosis Diseases 0.000 description 2
- 229910001220 stainless steel Inorganic materials 0.000 description 2
- 239000010935 stainless steel Substances 0.000 description 2
- 208000007536 Thrombosis Diseases 0.000 description 1
- HZEWFHLRYVTOIW-UHFFFAOYSA-N [Ti].[Ni] Chemical compound [Ti].[Ni] HZEWFHLRYVTOIW-UHFFFAOYSA-N 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 229940000425 combination drug Drugs 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000001647 drug administration Methods 0.000 description 1
- 230000000857 drug effect Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000003628 erosive effect Effects 0.000 description 1
- 238000002513 implantation Methods 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 229910001000 nickel titanium Inorganic materials 0.000 description 1
- 230000036285 pathological change Effects 0.000 description 1
- 231100000915 pathological change Toxicity 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
- 210000000329 smooth muscle myocyte Anatomy 0.000 description 1
- 238000007711 solidification Methods 0.000 description 1
- 230000008023 solidification Effects 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 231100000216 vascular lesion Toxicity 0.000 description 1
- 238000009941 weaving Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/10—Balloon catheters
- A61M25/104—Balloon catheters used for angioplasty
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0021—Catheters; Hollow probes characterised by the form of the tubing
- A61M25/0023—Catheters; Hollow probes characterised by the form of the tubing by the form of the lumen, e.g. cross-section, variable diameter
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0043—Catheters; Hollow probes characterised by structural features
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M2025/0004—Catheters; Hollow probes having two or more concentrically arranged tubes for forming a concentric catheter system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0043—Catheters; Hollow probes characterised by structural features
- A61M2025/0057—Catheters delivering medicament other than through a conventional lumen, e.g. porous walls or hydrogel coatings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/10—Balloon catheters
- A61M2025/1043—Balloon catheters with special features or adapted for special applications
- A61M2025/105—Balloon catheters with special features or adapted for special applications having a balloon suitable for drug delivery, e.g. by using holes for delivery, drug coating or membranes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Anesthesiology (AREA)
- Biophysics (AREA)
- Pulmonology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Vascular Medicine (AREA)
- Media Introduction/Drainage Providing Device (AREA)
Abstract
The application belongs to the technical field of medical instruments, and provides a balloon catheter structure, which comprises a balloon catheter, a first sleeve, a second sleeve and a third sleeve; the balloon catheter extends in a tubular shape and is provided with a catheter part and a balloon part connected with the catheter part; the third sleeve is inserted into the balloon catheter; the first sleeve is at least sleeved outside the balloon part; a first open hole is formed in the position, opposite to the balloon part, of the first sleeve; the second sleeve is sleeved outside the first sleeve and rotates around the central axis of the first sleeve; a second open hole is formed in a position, opposite to the balloon part, of the second sleeve; the second sleeve is switched between a first position and a second position by rotation; wherein when the second sleeve is at the first position, the first open hole is communicated with the second open hole; in the second position, the first open hole and the second open hole are staggered. The application aims to solve the technical problem that the drug-carrying balloon part in the prior art has serious drug loss in the process of conveying.
Description
Technical Field
The application belongs to the technical field of medical instruments, and particularly relates to a balloon catheter structure.
Background
The balloon catheter with the drug coating (for short, balloon catheter) is a balloon catheter with the drug coating loaded on the surface of a common bare balloon, after the balloon loaded with the drug is conveyed to a lesion site, the balloon expands to restore the vascular wall of the lesion site to be smooth, and the drug coating is eluted from the surface of the balloon and released to the vascular wall, so that proliferation of smooth muscle cells can be further inhibited, and vascular restenosis can be prevented. Therefore, the drug-coated balloon catheter not only can be expanded into blood circulation to establish a channel through the balloon, but also can avoid the defects of restenosis, thrombus and the like in the stent after the stent implantation operation.
Prior art drug coated balloon catheters generally use a balloon catheter having a balloon portion to which a drug coating is applied on the outer surface thereof, and then the drug-carrying balloon is delivered to the lesion and then expanded according to the characteristics of the lesion. However, in the process of conveying the drug coated balloon catheter in a blood vessel, the drug loss rate is up to more than 50% due to the scouring of high-speed flowing blood, so that the drug dosage of the drug coated balloon at a lesion site is reduced, and the effectiveness of the instrument is influenced; meanwhile, after the medicine washed by blood falls off, the remote blood vessel can be blocked, the metabolic burden of the organism is increased, and the safety of the instrument is reduced.
Disclosure of Invention
The application aims to provide a balloon catheter structure, which aims to solve the technical problems that in the prior art, the drug loss of a drug-loaded balloon part is serious in the process of delivery, and the drug release amount of the balloon part at a lesion part is reduced.
The application aims to provide a balloon catheter structure, which comprises the following components:
a balloon catheter extending in a tubular shape, the balloon catheter having a catheter portion and a balloon portion connected to the catheter portion;
the first sleeve is at least sleeved outside the balloon part; a first opening hole is formed in the position, opposite to the balloon part, of the first sleeve;
the second sleeve is sleeved outside the first sleeve and can rotate around the central axis of the first sleeve relative to the first sleeve; a second open hole is formed in a position, opposite to the balloon part, of the second sleeve; the second sleeve is capable of being rotationally switched between a first position and a second position by rotation; and
The third sleeve is inserted into the accommodating cavity of the balloon catheter;
wherein the first open bore is in opposing communication with the second open bore when the second sleeve is in the first position; the first open aperture is offset from the second open aperture when the second sleeve is in the second position.
Further, a plurality of first open holes are formed, and the first open holes are arranged around the central axis of the first sleeve at intervals; the second open holes are provided with one, and the second open holes can be communicated with each first open hole oppositely 。
Further, the number of the second open holes is the same as that of the first open holes, and the second open holes are arranged in one-to-one correspondence with the first open holes, so that when in the first position, each second open hole is communicated with the corresponding first open hole relatively, and when in the second position, each second open hole is dislocated and avoided from the corresponding first open hole.
Further, the device further comprises a light-emitting structure connected to the third sleeve, wherein the light-emitting structure is arranged close to the balloon part and can be arranged opposite to the first open hole, so that light emitted by the light-emitting structure can irradiate on the balloon wall of the balloon part corresponding to the first open hole; the outer side of the balloon wall of the balloon part is used for being coated with a drug coating containing a photosensitizer.
Further, the light-emitting device further comprises a control structure, wherein the control structure is in communication connection with the light-emitting structure and is used for controlling the light-emitting intensity and the light-emitting time of the light-emitting structure.
Further, the balloon wall of the balloon portion is provided with protruding structures extending towards the direction away from the center of the balloon portion, the number of the protruding structures is the same as that of the first open holes, and when the balloon portion expands, the protruding structures can be correspondingly inserted into the first open holes.
Further, the third sleeve comprises a first layer structure and a second layer structure sleeved outside the first layer structure, and the first layer structure is an annular plate-shaped piece made of polytetrafluoroethylene; the second layer structure comprises a first connecting section and a second connecting section connected with one end of the first connecting section, the first connecting section is positioned at the proximal end, the first connecting section is of a braided wire structure or a braided wire and spring winding structure, and the second connecting section is of a spring winding structure.
Further, the catheter also comprises a fixed handle and a rotating handle rotationally connected with the fixed handle, wherein the fixed handle is fixedly connected with the balloon catheter and the proximal end of the third sleeve, and the rotating handle is fixedly connected with the second sleeve.
Further, the first sleeve extends from the balloon portion to a proximal end of the balloon catheter and is fixedly connected with the fixed handle.
Further, the proximal end of the balloon catheter is connected with a pressurizing interface communicated with the accommodating cavity, and the pressurizing interface is used for flushing gas into the accommodating cavity; the proximal end of the balloon catheter is also connected with an electric connection port communicated with the accommodating cavity, and the electric connection port is used for inserting a conductive component; the proximal end of the balloon catheter is also connected with a guide wire interface communicated with the accommodating cavity, and the guide wire interface is used for inserting a guide wire into the accommodating cavity.
Compared with the prior art, the balloon catheter structure provided by the application has the beneficial effects that: compared with the prior art, in the balloon catheter structure, the first open hole and the second open hole are dislocated and avoided, and the second sleeve has a protective effect on the drug coating on the surface of the balloon part, so that the scouring of blood flow to the drug coating in the conveying process can be reduced or avoided, the drug loss rate in the conveying process is effectively reduced, the effectiveness of the balloon catheter structure is improved, and meanwhile, the falling drug can be reduced or avoided from being scoured to a far-end blood vessel and blocking the blood vessel by blood; after reaching the lesion site, rotating the rotatable second sleeve to a first position around the central axis, and exposing the balloon part extending out of the first opening hole and the second opening hole to the vascular environment so as to perform drug loading treatment on the lesion site on the inner wall of the blood vessel; when the balloon catheter structure is pulled out, the second sleeve rotates to the second position, so that friction between the balloon part and the blood vessel wall is reduced, and the blood vessel wall is protected.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present application, the following description will briefly explain the embodiments of the present application or the drawings used in the description of the prior art, and it is obvious that the drawings described below are only some embodiments of the present application, and other drawings can be obtained according to these drawings without inventive effort for a person skilled in the art.
Fig. 1 is a schematic perspective view of a balloon catheter structure according to an embodiment of the present application;
FIG. 2 is a schematic view of the first sleeve of FIG. 1;
FIG. 3 is a cross-sectional view of FIG. 1;
FIG. 4 is a view A-A of FIG. 3;
fig. 5 is a schematic structural view of a balloon portion in a balloon catheter structure according to an embodiment of the present application;
FIG. 6 is a schematic cross-sectional outer profile configuration of the balloon portion of FIG. 5;
FIG. 7 is a cross-sectional view of another balloon catheter structure provided in accordance with an embodiment of the present application in a balloon site position;
FIG. 8 is a schematic structural view of a balloon catheter according to another embodiment of the present application;
fig. 9 is a schematic cross-sectional view of fig. 8.
Reference numerals illustrate: 1. a second sleeve; 11. a second open hole; 2. a first sleeve; 21. a first open hole; 3. a balloon catheter; 31. a receiving chamber; 32. a balloon portion; 321. a bump structure; 322. a groove structure; 33. a conduit portion; 34. an electrical connection port; 35. a pressurizing interface; 36. a guidewire interface; 4. a third sleeve; 41. weaving filaments; 5. a light emitting structure; 6. rotating the handle; 7. a fixed handle; 8. a guide wire.
Detailed Description
Embodiments of the present application are described in detail below, examples of which are illustrated in the accompanying drawings, wherein like or similar reference numerals refer to like or similar elements or elements having like or similar functions throughout. The embodiments described below by referring to the drawings are illustrative and intended to explain the present application and should not be construed as limiting the application.
In the description of the present application, it should be understood that the terms "length," "width," "upper," "lower," "upward," "vertical," "horizontal," "bottom," "inner," "outer," and the like indicate orientations or positional relationships based on the orientation or positional relationships shown in the drawings, merely to facilitate describing the present application and simplify the description, and do not indicate or imply that the devices or elements referred to must have a specific orientation, be configured and operated in a specific orientation, and thus should not be construed as limiting the present application.
Furthermore, the terms "first," "second," and the like, are used for descriptive purposes only and are not to be construed as indicating or implying a relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defining "a first" or "a second" may explicitly or implicitly include one or more such feature. In the description of the present application, the meaning of "a plurality" is two or more, unless explicitly defined otherwise.
In the present application, unless explicitly specified and limited otherwise, the terms "mounted," "connected," "secured," and the like are to be construed broadly, and may be, for example, fixedly connected, detachably connected, or integrally formed; can be mechanically or electrically connected; can be directly connected or indirectly connected through an intermediate medium, and can be communicated with the inside of two elements or the interaction relationship of the two elements. The specific meaning of the above terms in the present application can be understood by those of ordinary skill in the art according to the specific circumstances.
The present application will be described in further detail with reference to the drawings and examples, in order to make the objects, technical solutions and advantages of the present application more apparent.
Referring to fig. 1-3, an embodiment of the present application provides a balloon catheter structure, which includes a balloon catheter 3, a first sleeve 2, a second sleeve 1, and a third sleeve 4; the balloon catheter 3 extends in a tubular shape and has a housing chamber 31 formed therein, the balloon catheter 3 having a catheter portion 33 and a balloon portion 32 connected to the catheter portion 33, the balloon portion 32 being capable of performing expansion deformation with an increase in volume; the third sleeve 4 is inserted into the accommodating cavity 31 of the balloon catheter 3.
The first sleeve 2 is at least sleeved outside the balloon portion 32, so that the balloon portion 32 can be accommodated in the first sleeve 2 before being expanded; a first open hole 21 is formed in a position of the first sleeve 2 opposite to the balloon portion 32, and the first open hole 21 can be opposite to the balloon portion 32; the second sleeve 1 is sleeved outside the first sleeve 2 and can rotate around the central axis of the first sleeve 2 relative to the first sleeve 2; a second open hole 11 is formed in a position, opposite to the balloon part 32, of the second sleeve 1, and the second open hole 11 is opposite to the balloon part 32; the second sleeve 1 can be switched rotationally between a first position and a second position by rotation relative to the first sleeve 2; wherein, when the second sleeve 1 is in the first position, the first open hole 21 and the second open hole 11 are arranged in opposite communication, so that the balloon part 32 is inflated outwards when being expanded and can protrude out of the first sleeve 2 through the first open hole 21 and the second open hole 11; when the second sleeve 1 is in the second position, the first opening 21 and the second opening 11 are arranged in a dislocation and avoiding way.
Specifically, the balloon catheter 3 includes a catheter portion 33 and a balloon portion 32 connected to a distal end of the catheter portion 33, the balloon portion 32 includes a working section at a middle portion and two transition sections connected to both ends of the working section, the working section is substantially cylindrical, the transition sections are tapered from one end connected to the working section to a direction away from the working section, and the transition sections of one end are connected to the catheter portion 33.
The outer surface of the balloon wall of the balloon portion 32 (or the outer surface of the balloon portion 32) is coated with a drug coating, wherein the drug coating contains an active drug for treating a focus, and the coating process of the active drug is an existing process and will not be described herein. The cylindrical working section of the balloon portion 32 can ensure that the filled balloon portion 32 has good adherence, and can effectively transfer active drugs to the inner wall of a blood vessel of a lesion site.
The interior of the balloon catheter 3 is provided with a containing cavity 31, the containing cavity 31 is also called a guide wire cavity, the containing cavity 31 is mainly used for penetrating the guide wire 8, and when in use, the guide wire 8 can be penetrated in the guide wire cavity and pushed to a vascular lesion along with the balloon catheter structure.
The third sleeve 4 extends in the same direction as the balloon catheter 3, the distal end of the third sleeve 4 can be fixedly connected with the distal end of the balloon catheter 3, and the distal end part of the accommodating cavity at the position of the balloon part 32 is closed, so that the balloon part 32 can be filled; the proximal end of the third cannula 4 is capable of communicating with a guidewire interface 36 (described below); the third cavity is offered to the inside of third sleeve pipe 4, and the both ends and the external intercommunication of third cavity, and the third cavity is used for holding seal wire 8 (or seal wire apparatus), and seal wire 8 can peg graft in the third cavity of third sleeve pipe 4 for play the effect of supporting whole sacculus pipe structure, during the use, seal wire 8 follows the sacculus pipe structure and advances to the vasculopathy position together.
The first sleeve 2 can be tubular or cylindrical, a first cavity is formed in the middle of the first sleeve 2, the pipe body of the first sleeve 2 can be sleeved at least on the outer part of the balloon part 32 so as to shield the outer part of the balloon part 32, the balloon part 32 can be accommodated in the first sleeve 2 before being expanded, and the central axis of the first sleeve 2 is approximately parallel or approximately overlapped with the central axis of the balloon catheter 3; at least one first open hole 21 is formed in the wall of the first sleeve 2, and the first open hole 21 can be arranged opposite to the outer wall of the balloon portion 32, so that the balloon portion 32 can protrude outwards through the first open hole 21 when being expanded.
The structure of the first sleeve 2 may be configured to be a tubular structure extending along the entire length of the balloon catheter 3, the first sleeve 2 may be sleeved not only on the balloon portion 32 but also on the catheter portion 33, and the distal end of the first sleeve 2 may extend to the proximal end and be integrally sleeved outside the balloon catheter 3.
The second sleeve 1 is tubular or cylindrical, a second cavity is formed in the middle of the second sleeve 1, so that the balloon catheter 3 can be inserted into the first cavity, the second sleeve 1 is sleeved outside the first sleeve 2, and the central axis of the second sleeve 1 is approximately parallel to or approximately coincident with the central axis of the first sleeve 2 or the balloon catheter 3. At least one second open hole 11 is arranged on the pipe wall of the second sleeve 1, the second open hole 11 is opposite to the balloon portion 32, the second open hole 11 can also be opposite to the first open hole 21, and when the second open hole 11 is opposite to the first open hole 21, the balloon portion 32 can be outwards protruded through the first open hole 21 and the second open hole 11 when being expanded.
The second sleeve 1 can rotate around the central axis of the first sleeve 2 relative to the first sleeve 2, so that the second sleeve 1 can be switched between a first position and a second position by rotation, wherein in the second position, the first open hole 21 and the second open hole 11 are dislocated and are not communicated relatively, so that the pipe wall of the second sleeve 1 can also cover the balloon part 32 at the position of the first open hole 21; in the first position, the first open aperture 21 is communicably opposed to the second open aperture 11 such that the balloon portion 32, when inflated, is able to project outwardly through the first and second open apertures 21, 11 in sequence.
The second sleeve 1 adopts the structure that the reinforcing ribs are additionally arranged in the second sleeve, the reinforcing ribs are arranged in a plurality of ways, the length dimension of each reinforcing rib is 0.02mm-10mm, and the pushing performance and the operability of the second sleeve 1 are improved.
The use method of the balloon catheter structure comprises the steps that before the balloon catheter structure is conveyed, the balloon portion 32 is coated with a drug coating, the balloon portion 32 is in a folded state, the second sleeve 1 is in a second position by rotating the second sleeve 1, the first open hole 21 can be blocked by the wall of the second sleeve 1, the balloon portion 32 is blocked, and the balloon portion 32 is not exposed; the balloon catheter structure is conveyed to a lesion part in a state of being kept, after the balloon catheter structure reaches the lesion part, the second sleeve 1 is rotated to enable the second sleeve 1 to be in a first position, the balloon part 32 is expanded, the balloon part 32 and the first sleeve 2 and the second sleeve 1 are spread together, and then the position, opposite to the first opening hole 21, of the balloon part 32 protrudes outwards through the first opening hole 21 and the second opening hole 11, so that a medicine coating on the outer wall surface of the balloon part 32 can be coated on the lesion part on the wall of the blood vessel, and the purposes of medicine coating and treatment on the lesion part are achieved; after the coating is finished, the second sleeve 1 is rotated to be in the first position, the wall of the second sleeve 1 shields the first open hole 21, the balloon portion 32 is further shielded, and the balloon portion 32 is contracted, so that the whole balloon catheter structure is pulled out of the blood vessel.
In the present embodiment, in the conveying process of the balloon catheter structure, the first open hole 21 and the second open hole 11 are dislocated and avoided, and the second sleeve 1 has a protective effect on the drug coating on the surface of the balloon portion 32, so that the erosion of blood flow to the drug coating in the conveying process can be reduced or avoided, the drug loss rate in the conveying process is effectively reduced, the utilization rate of the drug is increased, the loss of the drug in the blood circulation is reduced, the release efficiency of the drug is improved, the effectiveness of the balloon catheter structure is improved, and meanwhile, the falling drug can be reduced or avoided from being eroded to a distal blood vessel by blood, blocking the blood vessel and increasing the trafficability of the balloon catheter structure; after reaching the lesion site, the rotatable second sleeve 1 is rotated to a first position around the central axis, and the balloon part 32 extends out of the first open hole 21 and the second open hole 11 and is exposed to the vascular environment so as to perform drug administration treatment on the lesion site of the inner wall of the blood vessel; when the balloon catheter structure is withdrawn, the second sleeve 1 rotates to the second position, so that friction between the balloon portion 32 and the vessel wall is reduced, and the vessel wall is protected.
In addition, the balloon catheter structure can reduce the drug loss rate, reduce the initial drug loading rate on the surface of the balloon portion 32, lighten the metabolic burden of the body and improve the safety of the balloon catheter structure.
Referring to fig. 1 and 2, in one embodiment, the first open holes 21 are provided in plurality, and the plurality of first open holes 21 are circumferentially arranged at intervals around the central axis of the first sleeve 2; the second open holes 11 are provided one, and the second open holes 11 can be in opposite communication with each of the first open holes 21.
In this embodiment, after the balloon portion 32 reaches the lesion site, the second open hole 11 can be sequentially and respectively communicated with the first open hole 21 in a relative manner by rotating the second sleeve 1 multiple times, so that different portions of the balloon portion 32 coated with the drug can be sequentially attached to different portions of the lesion, and the drug can be sequentially applied to the portions of the lesion or the lesions of each portion of the blood vessel, thereby having stronger pertinence; or, also can be in the in-process of rotating second sleeve pipe 1, through whole rotation sacculus pipe 3 for first uncovered hole 21 and the uncovered hole 11 of second aim at a pathological change position all the time, carry out repeated medicine application, in order to reach the volume of using medicine of predetermineeing, it is more convenient to use, and is strong to the pertinence.
Referring to fig. 1 and 2, in one embodiment, the number of second open holes 11 is the same as the number of first open holes 21, and the second open holes 11 are disposed in one-to-one correspondence with the first open holes 21, so that in the first position, each second open hole 11 is in opposite communication with the corresponding first open hole 21, and in the second position, each second open hole 11 is capable of dislocating avoidance with the corresponding first open hole 21.
In this embodiment, the first open holes 21 and the second open holes 11 are set in groups, one first open hole 21 corresponds to one second open hole 11, and when the second sleeve 1 is in the second position, each second open hole 11 is not communicated with each first open hole 21, so that the pipe wall of the second sleeve 1 can cover the first open hole 21 to protect the balloon portion 32; when the second sleeve 1 rotates to the first position, the second open holes 11 are communicated with the corresponding first open holes 21 in a one-to-one correspondence manner, so that the balloon portions 32 positioned at the positions of the second open holes 11 and the first open holes 21 can apply medicines to the lesion positions, the medicine application area is increased, and the medicine application amount is ensured.
Referring to fig. 5 to 7, in one embodiment, the balloon wall of the balloon portion 32 has a protrusion structure 321 extending toward a direction away from the center of the balloon portion 32, the drug coating is mainly protruded on the outer surface of the protrusion structure 321, the number of the protrusion structures 321 is the same as that of the first open holes 21, and when the balloon portion 32 expands, the protrusion structure 321 can be correspondingly inserted into the first open holes 21 and protruded outside the first open holes 21 to contact with the lesion position.
Specifically, referring to fig. 5, the protrusion structure 321 is mainly located at a working section of the balloon portion 32, the protrusion structure 321 extends along an outer balloon wall of the working section, and an extending length of the protrusion structure 321 is smaller than or equal to a length of the first open hole 21, so that the protrusion structure 321 can penetrate out of the first open hole 21, when the number of the first open holes 21 is multiple, the protrusion structures 321 encircle and are arranged at intervals around a central axis of the balloon portion, the protrusion structures 321 are in one-to-one correspondence with the first open holes 21, and after the balloon portion 32 expands and expands, a groove structure 322 is formed between adjacent protrusion structures 321.
In the present embodiment, referring to fig. 7, by forming the outer wall of the balloon portion 32 with the protrusion structure 321 corresponding to the first open hole 21, the protrusion structure 321 coated with the drug coating can protrude outside the balloon portion 32 through the first open hole 21 and the second open hole 11 more rapidly when the balloon portion 32 is expanded, and the contact between the protrusion structure 321 and the lesion can be better achieved.
Referring to fig. 3 and 8, in one embodiment, the balloon catheter structure further includes a light emitting structure 5 connected to the third sleeve 4, the light emitting structure 5 is disposed in the accommodating cavity 31 of the balloon catheter 3 and is disposed near the balloon portion 32, and the light emitting structure 5 can be disposed opposite to the first open hole 21, so that the light emitted by the light emitting structure 5 can irradiate the balloon wall of the balloon portion 32 corresponding to the first open hole 21; the outside of the balloon wall of balloon portion 32 is coated with a drug coating containing a photosensitizer.
Specifically, the light emitting structure 5 may be independently located in the accommodating cavity 31, or connected and fixed to the inner side surface of the balloon wall of the balloon portion 32, and the light emitted by the light emitting structure 5 can irradiate on the balloon wall of the balloon portion 32 opposite to the first opening hole 21, or the light emitting structure 5 is connected to the distal end of the third sleeve 4, and the light emitting structure 5 may be sleeved on the outer wall surface of the wall of the third sleeve 4; the light emitting structure 5 may include 1 to 10 light emitting lamps.
In this embodiment, the drug coating coated on the outer surface of the balloon wall of the balloon portion 32 is a drug coating containing a photosensitizer, the drug coating wraps the drug by a photosensitizer compound, and after reaching a lesion position, the drug coating emits light by a light emitting structure 5 to perform illumination, and the photosensitizer phospholipid compound or the combination drug with a photosensitizer carrier is cured by illumination, so that the drug can be adhered to the lesion position after curing, the scouring loss of the drug in the blood flow process of blood vessels can be reduced, and the release efficiency of the drug is improved.
In one embodiment, the balloon catheter structure further comprises a control structure communicatively connected to the light emitting structure 5 for controlling the light emitting intensity and light emitting time of the light emitting structure 5; the control structure can control the light-emitting structure 5 to emit light and irradiate when the balloon reaches the lesion, and when the medicine is coated on the lesion, the control structure controls the light-emitting structure 5 to be closed.
Specifically, the control structure may be disposed outside the balloon catheter 3, and the control structure may be connected to the light emitting structure 5 by a wired or wireless manner, and when a wired connection manner is adopted, the wires may be disposed in the accommodating cavity 31 of the balloon catheter 3.
In this embodiment, the control structure is provided to control the light emitting intensity and the light emitting time of the light emitting structure 5, so that the light emitting structure 5 can fully irradiate the drug coating containing the photosensitizer, thereby ensuring the full solidification of the drug coating at the lesion site and further ensuring the drug effect.
Referring to fig. 3 and 8, in one embodiment, the third sleeve 4 includes a first layer structure and a second layer structure sleeved outside the first layer structure, wherein the first layer structure is an annular plate-shaped member made of Polytetrafluoroethylene (PTFE); the second layer structure comprises a first connecting section and a second connecting section connected with one end of the first connecting section, the first connecting section is located at the proximal end, the first connecting section is of a braided wire structure or a braided wire 41 and spring winding structure, the braided wire 41 is made of stainless steel, the second connecting section is of a spring winding structure, and the spring material is made of stainless steel or nickel titanium.
In the present embodiment, the first connection section of the second layer structure adopts a braided wire structure or a braided wire 41 and spring wound structure, so that the pushability and the operability of the balloon catheter 3 can be enhanced, and the second connection section adopts a spring wound structure, so that the flexibility of the balloon catheter 3 can be enhanced.
In one embodiment, referring to fig. 8 and 9, the balloon catheter structure further includes a fixed handle 7 and a rotating handle 6 rotatably connected to the fixed handle 7, the fixed handle 7 is fixedly connected to the proximal end of the balloon catheter 3, and the rotating handle 6 is fixedly connected to the second sleeve 1.
Specifically, the fixed handle 7 is located at the proximal end of the balloon catheter 3 and is fixedly connected with the proximal end of the balloon catheter 3, and when the first sleeve 2 is integrally sleeved on the balloon catheter 3, the first sleeve 2 extends from the balloon portion 32 to the proximal end of the catheter portion 33 and is fixedly connected with the fixed handle 7, and the distal end of the third sleeve 4 can also be fixedly connected with the fixed handle 7, so that the fixed handle 7 and the balloon catheter 3, the first sleeve 2 and the third sleeve 4 form an integral body and can rotate relative to the rotating handle 6 and the second sleeve 1 fixedly connected with the rotating handle 6.
In the present embodiment, the fixed handle 7 and the rotary handle 6 are disposed at the distal end of the balloon catheter 3, so that the second sleeve 1 rotates more conveniently and is easy to operate relative to the first sleeve 2.
Referring to fig. 8 and 9, in one embodiment, a pressurizing port 35 is connected to the proximal end of the balloon catheter 3 and is disposed in communication with the accommodating cavity 31 of the balloon catheter 3, and the pressurizing port 35 is used for flushing medium (gas) into the accommodating cavity 31 to inflate the balloon portion 32, so that the balloon portion 32 expands or depressurizes outwards; the proximal end of the balloon catheter 3 is also connected with an electrical connection port 34 which is communicated with the accommodating cavity 31, the electrical connection port 34 is used for inserting a conductive component so as to enable the conductive component to be electrically connected with the light-emitting structure 5, and in the structure with the third sleeve 4, the electrical connection port 34 is connected with the proximal end of the third sleeve 4; the proximal end of the balloon catheter 3 is further connected with a guide wire interface 36 which is communicated with the accommodating cavity 31, the guide wire interface 36 is used for inserting the guide wire 8 into the accommodating cavity 31, in the structure with the third sleeve 4, the guide wire interface 36 is communicated with the proximal end of the third sleeve 4, so that the guide wire 8 is inserted into the third sleeve 4 through the guide wire interface 36 and can penetrate out from the distal end of the third sleeve 4, and the guide wire interface 36 can also be connected to the fixed handle 7.
The foregoing description of the preferred embodiments of the present application has been provided for the purpose of illustrating the general principles of the present application and is not to be construed as limiting the scope of the application in any way. Any modifications, equivalent substitutions and improvements made within the spirit and principles of the present application, and other embodiments of the present application as will occur to those skilled in the art without the exercise of inventive faculty, are intended to be included within the scope of the present application.
Claims (9)
1. Balloon catheter structure, its characterized in that includes:
a balloon catheter extending in a tubular shape, the balloon catheter having a catheter portion and a balloon portion connected to the catheter portion;
the first sleeve is at least sleeved outside the balloon part; a first opening hole is formed in the position, opposite to the balloon part, of the first sleeve;
the second sleeve is sleeved outside the first sleeve and can rotate around the central axis of the first sleeve relative to the first sleeve; a second open hole is formed in a position, opposite to the balloon part, of the second sleeve; the second sleeve is capable of being rotationally switched between a first position and a second position by rotation; and
The third sleeve is inserted into the accommodating cavity of the balloon catheter;
the balloon wall of the balloon part is provided with protruding structures extending towards the direction far away from the center of the balloon part, the number of the protruding structures is the same as that of the first open holes, and when the balloon part expands, the protruding structures can be correspondingly inserted into the first open holes;
wherein when the second sleeve is in the first position, the first open hole and the second open hole are arranged in opposite communication, so that the balloon part is inflated outwards when being expanded, and can protrude out of the first sleeve through the first open hole and the second open hole; when the second sleeve is positioned at the second position, the first open hole and the second open hole are staggered to avoid, and the wall of the second sleeve can shield the first open hole and the balloon part, so that the balloon part is not exposed.
2. The balloon catheter structure of claim 1 wherein said first open bore is provided in a plurality, a plurality of said first open bores being circumferentially spaced about a central axis of said first sleeve; the second open holes are provided with one, and the second open holes can be communicated with each of the first open holes in an opposite way.
3. The balloon catheter structure of claim 1 wherein the number of second open cells is the same as the number of first open cells and the second open cells are disposed in a one-to-one correspondence with the first open cells such that in the first position, each of the second open cells is in opposing communication with a corresponding one of the first open cells and is capable of dislocating avoidance of each of the second open cells from a corresponding one of the first open cells in the second position.
4. The balloon catheter structure of any of claims 1-3, further comprising a light emitting structure coupled to the third sleeve, the light emitting structure disposed proximate the balloon portion and capable of being disposed opposite the first open aperture such that light emitted by the light emitting structure is capable of illuminating a balloon wall of the balloon portion corresponding to the first open aperture; the outer side of the balloon wall of the balloon part is used for being coated with a drug coating containing a photosensitizer.
5. The balloon catheter structure of claim 4 further comprising a control structure communicatively coupled to said light emitting structure for controlling the intensity and time of light emitted by said light emitting structure.
6. The balloon catheter structure of any one of claims 1-3, wherein the third sleeve comprises a first layer structure and a second layer structure sleeved outside the first layer structure, and the first layer structure is an annular plate-shaped piece made of polytetrafluoroethylene; the second layer structure comprises a first connecting section and a second connecting section connected with one end of the first connecting section, the first connecting section is positioned at the proximal end, the first connecting section is of a braided wire structure or a braided wire and spring winding structure, and the second connecting section is of a spring winding structure.
7. The balloon catheter structure of any of claims 1-3, further comprising a fixed handle and a rotating handle rotatably coupled to the fixed handle, the fixed handle fixedly coupled to proximal ends of the balloon catheter and the third cannula, the rotating handle fixedly coupled to the second cannula.
8. The balloon catheter structure of claim 7, wherein said first sleeve extends from said balloon portion to a proximal end of said balloon catheter and is fixedly connected to said fixed handle.
9. The balloon catheter structure of claim 8, wherein a proximal end of the balloon catheter is connected to a pressurizing port disposed in communication with the lumen of the balloon catheter, the pressurizing port being configured to flush gas into the lumen; the proximal end of the balloon catheter is also connected with an electric connection port communicated with the accommodating cavity, and the electric connection port is used for inserting a conductive component; the proximal end of the balloon catheter is also connected with a guide wire interface communicated with the accommodating cavity, and the guide wire interface is used for inserting a guide wire into the accommodating cavity.
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| CN202210994551.9A CN115414576B (en) | 2022-08-18 | 2022-08-18 | Balloon Catheter Structure |
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| CN202210994551.9A CN115414576B (en) | 2022-08-18 | 2022-08-18 | Balloon Catheter Structure |
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Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0920882A2 (en) * | 1997-12-04 | 1999-06-09 | Schneider Inc. | Balloon dilatation-drug delivery catheter and stent deployment-drug delivery catheter in rapid exchange configuration |
| CN1977993A (en) * | 2005-09-29 | 2007-06-13 | 西门子公司 | Combined oct catheter device and method for combined optical coherence tomography (OCT) diagnosis and photodynamic therapy (PDT) |
| DE102013112650A1 (en) * | 2013-11-15 | 2015-05-21 | Acandis Gmbh & Co. Kg | Balloon for a catheter and balloon catheter and system with such a balloon |
| CN113057718A (en) * | 2021-05-06 | 2021-07-02 | 哈尔滨医科大学 | Intravascular plaque cutting device |
| CN114225186A (en) * | 2021-12-15 | 2022-03-25 | 深圳市远为医疗技术有限公司 | Adjustable balloon catheter |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6540719B2 (en) * | 2000-12-08 | 2003-04-01 | Advanced Cardiovascular Systems, Inc. | Catheter with rotatable balloon |
| US6972030B2 (en) * | 2002-09-17 | 2005-12-06 | Lee Don W | Stent with combined distal protection device |
| US8702773B2 (en) * | 2008-12-17 | 2014-04-22 | The Spectranetics Corporation | Eccentric balloon laser catheter |
| US20170266421A1 (en) * | 2013-01-15 | 2017-09-21 | Krishna Rocha-Singh | Apparatus and method for delivering intraluminal therapy |
-
2022
- 2022-08-18 CN CN202210994551.9A patent/CN115414576B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0920882A2 (en) * | 1997-12-04 | 1999-06-09 | Schneider Inc. | Balloon dilatation-drug delivery catheter and stent deployment-drug delivery catheter in rapid exchange configuration |
| CN1977993A (en) * | 2005-09-29 | 2007-06-13 | 西门子公司 | Combined oct catheter device and method for combined optical coherence tomography (OCT) diagnosis and photodynamic therapy (PDT) |
| DE102013112650A1 (en) * | 2013-11-15 | 2015-05-21 | Acandis Gmbh & Co. Kg | Balloon for a catheter and balloon catheter and system with such a balloon |
| CN113057718A (en) * | 2021-05-06 | 2021-07-02 | 哈尔滨医科大学 | Intravascular plaque cutting device |
| CN114225186A (en) * | 2021-12-15 | 2022-03-25 | 深圳市远为医疗技术有限公司 | Adjustable balloon catheter |
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| Publication number | Publication date |
|---|---|
| CN115414576A (en) | 2022-12-02 |
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