CN115414558A

CN115414558A - Inhalation device

Info

Publication number: CN115414558A
Application number: CN202110608689.6A
Authority: CN
Inventors: 博江盟; 王祎哲
Original assignee: CF PHARMTECH Inc
Current assignee: CF PHARMTECH Inc
Priority date: 2021-06-01
Filing date: 2021-06-01
Publication date: 2022-12-02

Abstract

The application discloses suction device, including lid, suction nozzle, filter piece, apron, capsule storehouse, impale subassembly and base, wherein, equally divide at the front side and the rear side of apron and do not be equipped with air inlet to when producing the negative pressure in the suction channel of suction nozzle, form two side inlet channel. The inhalation device in this application makes inhalation device produce ideal air current trend under the user state through two side designs of admitting air, and the capsule in the help capsule storehouse produces motion such as vibration and/or rotation in order to release medicine powder, guarantees inhalation efficiency.

Description

Inhalation device

Technical Field

The application relates to the technical field of medical instruments, in particular to an inhalation device.

Background

In current methods of administration, drugs are taken by direct inhalation for some respiratory diseases. For example, a capsule with a medicament powder is pierced by a special administration device at the time of administration, and the medicament powder is inhaled into the respiratory tract. However, in the prior art, the conventional drug delivery device cannot effectively ensure the air intake efficiency due to structural design defects, and cannot realize an ideal air flow direction.

Disclosure of Invention

In view of the above-mentioned shortcomings of the related art, it is an object of the present application to provide an inhalation device to overcome the above-mentioned problems of the related art that the drug delivery device has low air intake efficiency and cannot achieve a desired air flow direction.

To achieve the above and other related objects, there is provided an inhalation device comprising a mouthpiece including a mouthpiece body and an inhalation passage formed in the mouthpiece body; the filter element is arranged at the bottom end of the suction channel and used for blocking capsule scraps generated after the capsule is punctured; the cover plate is arranged below the suction nozzle and is provided with a capsule placing port correspondingly combined with the filter element, and the near side and the far side of the cover plate are respectively provided with a first airflow inlet and a second airflow inlet; the capsule bin is positioned below the cover plate and is provided with a cavity used for containing the capsule in a use state, and the cavity is communicated with the capsule inlet of the cover plate; the piercing assembly comprises a button part and a piercing needle which are movably arranged on one side of the capsule bin, and the button part moves towards the capsule bin under a pressing state to drive the piercing needle to pierce the capsule in the capsule bin; a base including a seat body for accommodating the capsule magazine and a part of the piercing member, forming a first air inlet passage from the first air flow inlet to the chamber and a second air inlet passage from the second air flow inlet to the chamber in a state where the cover plate is covered on the base; the cover body covers the suction nozzle in a clamping state with the base; when negative pressure is generated in the cavity, the air flows of the first air inlet channel and the second air inlet channel form confluence at the bottom end of the cavity and enter the cavity, and the medicine powder in the punctured capsule in the cavity enters the suction channel through the capsule placing port and the filter element.

In some embodiments of the present application, the base, the cover plate and the distal end of the mouthpiece are coaxially connected by a first hinge, the cover and the distal end of the base are coaxially connected by a second hinge, and the first hinge and the second hinge are not coaxial.

In some embodiments of the present application, the cover has first engaging portions disposed on two sides thereof, and the first engaging portions penetrate through the first air inlet to engage with two side edges of the base.

In some embodiments of the present application, the tip of the lancet is formed by three inclined planes intersecting at the same point, and the tip is not coincident with an extension of the axial center line of the lancet.

In certain embodiments of the present application, the lancet needle has a diameter of 1mm to 2mm.

In some embodiments of the present application, the number of the needles is two and the needles are arranged in an up-down manner, and the distance between the two needles arranged in the up-down manner is smaller than the height of the capsule and is larger than half of the height of the capsule.

In some embodiments of the present application, the mouthpiece body comprises an operating portion located at a proximal side of the mouthpiece body for operating to approach or separate the mouthpiece body to or from the cover plate when in use; and the suction port part is integrally formed with the operation part, and is provided with the suction channel and the outline which is suitable for the mouth part of the human body.

In some embodiments of the present application, the proximal end of the operation portion has a concave structure.

In certain embodiments of the present application, the recessed feature has an operational indicia located thereon.

In certain embodiments of the present application, the ratio of the cross-sectional area of the suction channel to the sum of the areas of the first and second airflow inlets is from 1.

In certain embodiments of the present application, the filter member includes a mounting portion to be mounted to the suction passage, and a screen portion to filter.

In some embodiments of the present application, the bottom of the suction passage is a tubular structure, and the outer surface of the bottom end of the tubular structure and the inner surface of the mounting portion of the filter member have corresponding mounting structures, so as to set the filter member at the bottom end of the tubular structure.

In certain embodiments of the present application, the screen section comprises a convex surface in the shape of a circular arc in the center and ribs at the periphery of the convex surface.

In certain embodiments of the present application, the mesh diameter of the screen section is 0.6mm to 1mm or less.

In certain embodiments of the present application, the wire diameter of the screen section is between 0.1mm and 0.5mm.

In certain embodiments of the present application, the ratio of the total amount of mesh area of the screen section to the total amount of area of the first and second gas flow inlets is 1:3-1:2.

In certain embodiments of the present application, the screen section is stainless steel.

In certain embodiments of the present application, the screen section and the mounting section are integrated by ultrasonic welding and thereby forming a ring of protrusions on the surface of the mounting section.

In certain embodiments of the present application, the opposite faces of the filter element and the cover plate have end faces that are cooperatively shaped to provide a snug fit between the filter element and the cover plate.

In some embodiments of the present application, the cover plate has a plurality of air holes uniformly distributed on the surface opposite to the filter element, so as to help generate turbulence in the chamber when negative pressure is generated in the chamber, so as to generate vibration and/or rotation of the capsule.

In some embodiments of the present application, the mounting portion includes two second engaging portions located at the proximal end and extending downward, and the cover plate has two engaging holes corresponding to the two second engaging portions, respectively, for engaging the suction nozzle with the cover plate.

In some embodiments of the present application, the front and rear lower surfaces of the cover plate have protrusions; and a supporting part correspondingly combined with the bulge part is formed at the top of the inner side wall of the base and used for realizing the sealing and mutual supporting of the front side and the rear side of the base under the state that the cover plate covers the base.

In some embodiments of the present application, a third engaging portion is disposed on the protruding portion, and a fourth engaging portion corresponding to the third engaging portion is disposed on an upper side edge of the base.

In some embodiments of the present application, the cover plate has fifth engaging portions at both sides thereof, and the base has a sixth engaging portion at an upper edge thereof corresponding to the fifth engaging portion.

In some embodiments of the present application, the number of the first air inflow ports is two, and the first air inflow ports are respectively located on front and rear sides of the proximal end of the cover plate.

In certain embodiments of the present application, the first gas flow inlet has an area of 3.5 to 15mm each ² 。

In some embodiments of the present application, the number of the second airflow inlets is two, and the second airflow inlets are opened at two sides of the distal end of the cover plate.

In some embodiments of the present application, a third airflow inlet is further opened at a far side of the base, and the third airflow inlet is communicated with the second airflow inlet in a state where the cover is attached to the base.

In certain embodiments of the present application, the second airflow inlet is one in number and opens at a distal end of the cover plate.

In certain embodiments of the present application, the cover plate and capsule magazine are integrally formed.

In certain embodiments of the present application, the chamber of the capsule cartridge comprises a main chamber having a transverse diameter greater than the transverse cross-sectional diameter of the capsule and less than the longitudinal cross-sectional diameter of the capsule.

In certain embodiments of the present application, the ratio of the cross-sectional area of the primary chamber to the sum of the areas of the first and second gas flow inlets is 1:2-1.5.

In some embodiments of the present application, the capsule chamber is provided with a sub-chamber at the bottom of the chamber, the sub-chamber being in communication with the main chamber, the sub-chamber having a chamber inlet at the bottom end thereof, and a gap between the chamber inlet and the bottom surface of the base, the sub-chamber having a diameter smaller than the transverse cross-sectional diameter of the capsule.

In certain embodiments of the present application, the ratio of the cross-sectional area of the chamber inlet to the sum of the areas of the first and second gas flow inlets is 1:8-1:7.

In certain embodiments of the present application, the chamber of the capsule cartridge comprises mounting structure for cooperating with the piercing assembly such that the piercing assembly punctures a capsule within the capsule cartridge with its piercing needle during movement relative to the capsule cartridge.

In some embodiments of the present application, the mounting structure includes a mounting plate provided with symmetrical slots; the abutting part is formed on the mounting plate and is positioned between the symmetrical clamping grooves; and the two pipe parts are formed on the mounting plate, are respectively positioned at the upper side and the lower side of the abutting part, are communicated with the cavity and are used for limiting the puncturing direction of the puncture needle.

In certain embodiments of the present application, the piercing assembly further comprises a reset mechanism located between the button member and the abutment for being depressed upon movement of the button member in a direction towards the capsule compartment to provide a reset force to restore the piercing needle and the button member to an initial position.

In some embodiments of the present application, the button member is provided with a mounting block for mounting the return mechanism.

In some embodiments of the present application, the lancet is disposed through the tube portion, and the proximal end of the lancet is cooperatively coupled with the button member.

In some embodiments of the present application, the button member includes a pressing portion and a movable connecting portion integrally formed with the pressing portion, and a distal end of the movable connecting portion has a limiting portion engaged with the slot.

In some embodiments of the present application, the distal end of the lancet is on the same vertical line as the distal end of the articulating portion.

In some embodiments of the present application, the proximal end of the base is provided with an opening to provide a space for movement of the piercing assembly.

In some embodiments of the present application, the base further comprises a transparent window installed on the base body, and the cavity of the capsule chamber has a transparent wall surface for observing the state of the capsule in the capsule chamber through the base in the use state.

In some embodiments of the present application, the transparent window is located at the distal end of the base and extends to both the front and rear sides of the base.

In some embodiments of the present application, the base has a flow restriction plate with an air flow guide hole therein, so as to restrict the magnitude of the air flow and control the air intake direction of the air flow.

In certain embodiments of the present application, the restrictor plate is located distally within the base.

In some embodiments of the present application, the number of the air flow guiding holes is two, the two air flow guiding holes are symmetrically arranged on the flow restriction plate, and the area of each air flow guiding hole is 20-35 mm ² 。

In certain embodiments of the present application, the sum of the areas of the first and second gas flow inlets is 50 to 100mm ² 。

To sum up, inhalation in this application is through two side designs of admitting air to put many places designs such as gas pocket, restrictor plate of entrance through sieve portion structure, capsule, make inhalation produce ideal air current trend under the user state, the capsule in the help capsule storehouse produces vibration and/or rotation in order to release medicine powder, guarantees inhalation efficiency. In addition, the suction device can open the cover of the button through the matching of the button part, the cover body and the base, and is convenient to use. In addition, the double-shaft connection of the suction device, the supporting structure matched between the cover plate and the base and other parts are designed to ensure the service life of the product; the concave structure of the operating part of the suction nozzle can ensure the sanitary cleanliness in the using process, the position relation between the puncture needle and the movable connecting part is convenient for sensing the puncture position, the operation is convenient, and the design accords with the ergonomics.

Other aspects and advantages of the present application will be readily apparent to those skilled in the art from the following detailed description. Only exemplary embodiments of the present application have been shown and described in the following detailed description. As those skilled in the art will recognize, the disclosure of the present application enables those skilled in the art to make changes to the specific embodiments disclosed without departing from the spirit and scope of the invention as it is directed to the present application. Accordingly, the descriptions in the drawings and the specification of the present application are illustrative only and not limiting.

Drawings

The specific features of the invention to which this application relates are set forth in the appended claims. The features and advantages of the invention to which the present application relates will be better understood by reference to the exemplary embodiments and drawings described in detail below. The brief description of the drawings is as follows:

FIGS. 1 a-1 c are schematic exploded views of an inhalation device of the present application in one embodiment;

FIG. 2a is an exploded view of the filter of the present application in one embodiment;

FIG. 2b is a schematic view of the screen section and the mounting section before welding in one embodiment;

FIG. 2c is a schematic view of the screen section and the mounting section after welding in one embodiment;

FIG. 3 is a schematic view of a nozzle of the present application in one embodiment;

FIG. 4 is a schematic view of a cover plate according to an embodiment of the present application;

FIG. 5 is a schematic view of the air flow in the inhalation device of the present application in one embodiment;

FIG. 6 is a schematic view of the cover, lid and base of the present application in one embodiment;

FIG. 7 is a schematic view of the button member, cover plate, capsule chamber and cover of the present application in one embodiment;

FIGS. 8 a-8 c are schematic views of the button member, cover plate, capsule chamber and cover of the present application in another embodiment;

FIG. 9 is a schematic view of the cover and base of the present application in one embodiment;

FIG. 10 is a schematic view of the filter and cover of the present application in one embodiment;

FIG. 11 is a schematic view of the cover plate, capsule bin and capsule of the present application in one embodiment;

FIG. 12 shows a schematic view of a capsule according to the present application in one embodiment;

FIG. 13 shows a schematic view of a mouthpiece, filter and cover plate of the present application in one embodiment;

FIG. 14 is a schematic structural view of a cover plate according to another embodiment of the present application;

FIG. 15 shows a schematic view of the lancet needle of the present application in one embodiment;

FIG. 16 is a schematic view of a button member according to an embodiment of the present application;

FIG. 17 is a schematic view of a mounting structure of the present application in one embodiment;

FIGS. 18a and 18b are schematic views of a button member according to the present application in another embodiment;

FIG. 19 is a schematic view of a piercing assembly of the present application in one embodiment;

FIG. 20 is a schematic view of a button member according to the present application in a further embodiment;

FIG. 21 shows a schematic view of the lancet and button member of the present application in one embodiment;

FIG. 22 is a schematic view of a base according to an embodiment of the present application;

FIG. 23 is a schematic view of a cover plate according to yet another embodiment of the present application;

FIG. 24 is a schematic view of a cover and a base according to another embodiment of the present application;

FIG. 25 is a schematic view of a base according to the present application in a further embodiment;

figure 26 shows a schematic view of the air flow pattern of the inhalation device of the present application in one embodiment.

Detailed Description

The following embodiments are provided to illustrate the present disclosure, and other advantages and effects will be apparent to those skilled in the art from the disclosure.

In the following description, reference is made to the accompanying drawings that describe several embodiments of the application. It is to be understood that other embodiments may be utilized and that changes in the module or unit composition, electrical, and operation may be made without departing from the spirit and scope of the present disclosure. The following detailed description is not to be taken in a limiting sense, and the scope of embodiments of the present application is defined only by the claims of the issued patent. The terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the application.

Although the terms first, second, etc. may be used herein in some instances to describe various elements, information, or parameters, these elements or parameters should not be limited by these terms. These terms are only used to distinguish one element or parameter from another element or parameter. For example, the first intake passage may be referred to as the second intake passage, and similarly, the second intake passage may be referred to as the first intake passage, without departing from the scope of the various described embodiments. The first intake passage and the second intake passage are both described as one intake passage, but they are not the same intake passage unless the context clearly dictates otherwise. Depending on the context, for example, the word "if" as used herein may be interpreted as "at … …" or "at … …".

Also, as used herein, the singular forms "a", "an" and "the" are intended to include the plural forms as well, unless the context indicates otherwise. It will be further understood that the terms "comprises," "comprising," "includes" and/or "including," when used in this specification, specify the presence of stated features, steps, operations, elements, components, items, species, and/or groups, but do not preclude the presence, or addition of one or more other features, steps, operations, elements, components, species, and/or groups thereof. The terms "or" and/or "as used herein are to be construed as inclusive or meaning any one or any combination. Thus, "A, B or C" or "A, B and/or C" means "any of the following: a; b; c; a and B; a and C; b and C; A. b and C ". An exception to this definition will occur only when a combination of elements, functions, steps or operations are inherently mutually exclusive in some way.

As discussed in the background, in some embodiments, drug delivery devices for treating respiratory diseases typically have an air intake passage to provide air flow, but in some embodiments, such drug delivery devices typically have only one air intake passage with limited air intake. In addition, the design of these air inlet channels cannot realize an ideal air flow direction, thereby affecting the inhalation efficiency of the medicine powder in the capsule. Furthermore, in some related arts, some detailed designs of the medication administering device are not user-friendly, for example, a suction nozzle portion for interfacing with the mouth of a human body is easily contaminated in operation, inconvenient in operation when opening the medication administering device, etc., and the user experience is poor.

In view of the significant impact of inhalation efficiency on drug delivery efficiency and drug delivery effect of inhalation devices for drug delivery devices, and the requirement of such devices for hygiene, the present application provides an inhalation device which, in embodiments, facilitates inhalation of a drug powder from a capsule containing a powdered drug by a patient via the respiratory tract, and in some applications is also referred to as an inhaler, a powder inhaler, or a dry powder inhaler. In use, the capsule may be loaded into a capsule chamber located within the inhaler by the patient prior to use, and the patient may then press a button which actuates a spike to switch the spike from a rest condition to a moving condition to puncture the capsule located within the capsule chamber to cause the capsule to release powdered medicament therein under the influence of negative pressure. Examples of powdered medicaments include, but are not limited to: tiotropium Bromide (Tiotropium Bromide), indacaterol (Indacaterol), and the like can be administered by inhalation through the respiratory tract.

In an exemplary embodiment, referring to fig. 1 a-1 c, which are schematic exploded views of an embodiment of the inhalation device of the present application, the inhalation device comprises a cover 1, a mouthpiece 2, a filter 3, a cover 9, a capsule chamber 4, a piercing assembly 5, and a base 6.

The cover is a member for covering the suction nozzle 2 in a state of being engaged with the base 6, so as to prevent the suction nozzle from being contaminated by the outside.

In the present application, the engagement means a physical engagement manner that the two components can be quickly or conveniently fixed or separated from each other by using mechanical deformation (such as interference fit) or mechanical interference, in embodiments, for example, an engagement manner of a hook and a slot, an engagement manner of a hook and a hook, or an engagement manner of a protrusion and a groove, an engagement manner of a protrusion and a protrusion, etc., in the present application, the engagement structure between the two components will be described according to the mechanical structure of the different components in their respective specific implementation states and by using a diagram.

The suction nozzle is a component for sucking the medicine powder in the capsule chamber into the body in cooperation with the mouth of the human body, in this embodiment, please refer to fig. 3, which shows a schematic structural diagram of the suction nozzle in one embodiment of the present application, and the suction channel 22 is integrally formed in the suction nozzle body 21.

In the present application, the integrally molded structure means a structure in which a plurality of components having respective functions are integrated into one body and are not physically separated by a non-destructive means, and is generally integrated at a manufacturing stage, for example, by injection molding with a mold, or integrally molded by means of additive manufacturing (3D printing), or the like.

The filter element is used to indicate a component that has a filtering effect on the objects in the capsule chamber and is beneficial to generate an efficient inhalation airflow, and in the embodiment, please refer to fig. 1a to 1c continuously, the filter element 3 is sleeved at the bottom of the inhalation passage 22.

The cover plate 9 is positioned below the suction nozzle, the cover plate 9 is provided with a capsule inlet 91, the capsule inlet 91 is communicated with the capsule bin 4, and in a use state, a patient places capsules in the capsule bin 4 through the capsule inlet 91. The capsule inlet 91 is correspondingly combined with the filter member 3 so as to be tightly combined with the filter member to ensure the suction efficiency.

The capsule magazine is a component for containing capsules and holding the components connected to the piercing assembly, the cover plate, and the base, and with continued reference to fig. 1c, the capsule magazine is located below the cover plate 9, the capsule magazine includes a chamber 42, the chamber 42 is for containing capsules; in an embodiment, the capsule is placed in the chamber 42 in a substantially upright position, i.e. with one end of the capsule at the bottom of the chamber 42 and one end of the capsule adjacent the top of the chamber 42. In some embodiments, the cover plate 9 and the capsule chamber 4 can be integrally formed, so that the two are connected seamlessly, the manufacturing cost and difficulty are reduced, and the material and production cost is reduced.

Please refer to fig. 4, which is a schematic structural diagram of a cover plate according to an embodiment of the present application. As shown in the figure, a first air inlet 92 and a second air inlet 93 are respectively opened on the near side and the far side of the cover plate 9, and a first air inlet passage from the first air inlet 92 to the chamber 42 and a second air inlet passage from the second air inlet 93 to the chamber 42 are formed in a state where the cover plate 9 is covered on the base 6.

In this application, the communication means spatial communication such that an air stream or an air stream entrained medicament powder can pass through, and in some expressions, the communication is also used as communication, both meaning spatial connection of two physical spaces.

It should be noted that the capsule is not necessarily a part of the inhalation device, and in some cases, in order to prevent the powder in the capsule from being wetted, the capsule is taken out and put into the capsule chamber to suck the powder in the capsule only in the use state.

The piercing assembly is a component for piercing a capsule in the capsule compartment. The piercing assembly 5 is located at one side of the capsule chamber 4, the piercing assembly 5 comprises a button member 51 and a piercing needle 52, the button member 51 is movable relative to the capsule chamber, a channel for passing the piercing needle is arranged on a cavity of the capsule chamber 4, and in a use state, when a pressing force is applied to the button member, the button member moves relative to the capsule chamber and simultaneously drives the piercing needle 52 to pierce the capsule in the cavity 42. In this application, relative motion refers to movement of multiple components toward or away from each other. Hence, here, the button member is movable relative to the capsule magazine means that the button member can be moved closer or further away relative to the capsule magazine.

The base is used for accommodating the capsule chamber and is used as a part of the air flow channel, and the base 6 comprises a seat body 61, the seat body 61 is hollow inside and is used for accommodating the cavity 42 of the capsule chamber and part of the piercing component 5.

In the use mode of the embodiment, firstly, the cover body 1 and the suction nozzle 2 are opened, the capsule is placed on the capsule placing opening 91 on the cover plate 9, the capsule enters the cavity 42 from the capsule placing opening 91, then the suction nozzle 2 is covered on the cover plate 9 to enable the suction channel 22 to be communicated with the capsule placing opening 91, the puncture needle 52 is driven by the button piece 51 to puncture the capsule in the cavity 42 to form a medicine powder outlet on the capsule, and at the moment, a user holds the upper part of the suction nozzle by using the mouth and inhales, and negative pressure is generated in the suction channel. Referring to fig. 5, which is a schematic view of the flow direction in the inhalation device of the present application in one embodiment, as shown, the flow enters the base (not shown) from the first air inlet passage and the second air inlet passage, respectively, and forms a confluent flow into the chamber 42 at the bottom end thereof. Due to the fine diameter of the medicament powder, it leaves the capsule through its medicament powder outlet under negative pressure and is sucked into the user's body with the air flow through the filter element into the suction channel, while possible capsule debris is blocked by the filter element 3 from entering the suction channel.

It will be appreciated that the terms "proximal" and "distal" are used herein with respect to the piercing assembly, and thus in the various embodiments of the present application, for ease of description, the side of the inhalation device proximal to the piercing assembly will be defined as proximal and the side distal from the piercing assembly, i.e. the side where the

reference numerals

19, 29, 69b, 99 shown in fig. 1b of the present application are located, will be distal and the opposite will be proximal. In addition, the terms "front" and "rear" used in the present application are for convenience of explanation with respect to the viewing direction of the drawing, and specifically, the term "front" in the present application is defined as being directed to the left side of the direction of

reference numerals

19, 29, 69b, 99 with reference to the direction of the piercing member, i.e., the side closer to the viewing direction of the drawing in fig. 1 a; the "rear" in this application is defined as the side to the right of the direction of the

reference numerals

19, 29, 69b, 99, i.e. the side farther from the viewing direction of the diagram in fig. 1a, with reference to the direction of the piercing assembly. It will also be appreciated that for ease of description, spatial terms such as "top surface", "bottom surface", etc. are used herein in the context of the inhalation device placement presented in the figures. However, these spatial terms are not intended to be limiting and absolute in that the surgical medical instrument can be used in a variety of orientations and positions in a variety of use scenarios.

In an exemplary embodiment, with continued reference to fig. 4, the number of the first airflow inlets 92 is two, and the two inlets are respectively located at the front and rear sides of the proximal end of the cover plate. In a possible embodiment, the area of the first air inlet is 3.5-15 mm each to achieve a desired air intake amount ² E.g. 3.5mm ² 、4mm ² 、5mm ² 、6mm ² 、7mm ² 、8mm ² 、9mm ² 、10mm ² 、11mm ² 、12mm ² 、13mm ² 、14mm ² 、15mm ² And the like. In this embodiment, the first air inlet ports each have an area of 9mm ² 。

In some embodiments, the number of the first air inlets may also be one or more than two, as long as air intake from the near side of the cover plate can be achieved, for example, the first air inlets are opened only on one side of the cover plate near end, or a plurality of first air inlets are opened on both sides of the cover plate near end, respectively. Here, in order to secure the suction efficiency, the total area of the areas of the first air inflow openings added up may be 10 to 30mm ² E.g. 10mm ² 、11mm ² 、12mm ² 、13mm ² 、14mm ² 、15mm ² 、16mm ² 、17mm ² 、18mm ² 、19mm ² 、20mm ² 、21mm ² 、22mm ² 、23mm ² 、24mm ² 、25mm ² 、26mm ² 、27mm ² 、28mm ² 、29mm ² 、30mm ² And the like.

The number of the second airflow inlets can be one or more. For example, please refer to fig. 23, which is a schematic structural diagram of a cover plate according to another embodiment of the present application. As shown, the distal end of the cover plate is provided with a second air inlet 93, through which air can enter the base when a negative pressure is generated in the suction channel, on the one hand, through the first air inlet 92 located on the proximal side of the cover plate, and on the other hand, through the second air inlet 93 located on the distal side of the cover plate. For another example, as shown in fig. 4, the distal side of the cover plate is provided with a second air inlet 93 on each side of the first hinge portion, and when negative pressure is generated in the suction channel, the air flow can enter the base through the first air inlet 92 located on the proximal side of the cover plate on one hand, and can enter the base through the two second air inlets 93 located on the distal side of the cover plate on the other hand.

In some embodiments, please refer to fig. 24, which is a schematic structural view of the cover and the base in another embodiment of the present application, as shown in the figure, a third airflow inlet 65 may be further formed at a far side of the base, and after the cover is fastened to the base, the third airflow inlet 65 may communicate with the second airflow inlet 93, that is, cooperate together to form a gap, so that when a negative pressure is generated in the suction channel, a second air intake channel from the third airflow inlet 65 and the second airflow inlet 93 to the chamber may be formed.

In an exemplary embodiment, the sum of the areas of the first and second gas flow inlets may be 50 to 100mm ² E.g. 50mm ² 、51mm ² 、52mm ² 、53mm ² 、54mm ² 、55mm ² 、56mm ² 、57mm ² 、58mm ² 、59mm ² 、60mm ² 、61mm ² 、62mm ² 、63mm ² 、64mm ² 、65mm ² 、66mm ² 、67mm ² 、68mm ² 、69mm ² 、70mm ² 、71mm ² 、72mm ² 、73mm ² 、74mm ² 、75mm ² 、76mm ² 、77mm ² 、78mm ² 、79mm ² 、80mm ² 、81mm ² 、82mm ² 、83mm ² 、84mm ² 、85mm ² 、86mm ² 、87mm ² 、88mm ² 、89mm ² 、90mm ² 、91mm ² 、92mm ² 、93mm ² 、94mm ² 、95mm ² 、96mm ² 、97mm ² 、98mm ² 、99mm ² 、100mm ² And the like.

In an exemplary embodiment, the suction device may be coupled to the base by two shafts, i.e., the cover, the suction nozzle, the cover plate, and the base are coupled to each other by two shafts, respectively, for convenience of use. For example, the base, the cover plate and the distal end of the mouthpiece are coaxially connected by a first hinge, the cover body and the distal end of the base are coaxially connected by a second hinge, and the first hinge and the second hinge are not coaxial.

With continued reference to fig. 1b, the base 6, the cover plate 9, the suction nozzle 2 and the distal end of the cover 1 each have a hinge, wherein the cover and the base are coaxially connected by a second hinge (19, 69 b), and the suction nozzle 2, the cover plate 9 and the base 6 are coaxially connected by a first hinge (29, 99, 69 a), thereby simultaneously including a first hinge 69a and a second hinge 69b at the distal end of the base. The first hinge part and the second hinge part can be shaft holes, and the hinge connection between the parts is realized through a connecting shaft. Alternatively, the first hinge portion and the second hinge portion may be hinged by means of a protrusion and a shaft hole, as shown in fig. 1b, the first hinge portion 69a on the base and the first hinge portion 99 on the cover plate are both shaft holes, the first hinge portion 29 on the suction nozzle 2 is a protrusion with an approximately circular shape to be matched with the first hinge portion 69a and the first hinge portion 99 for realizing the hinge, and similarly, the second hinge portion 19 on the cover body is a shaft hole, and the second hinge portion 69b on the base 6 is a protrusion with an approximately circular shape to be matched with the second hinge portion 19 for realizing the hinge. It should be noted that the positions of the shaft hole and the protrusion in the embodiment are only examples and not limitations, and the specific application is not limited to these, the positions of the shaft hole and the protrusion may be interchanged, and the form of the first hinge portion and the second hinge portion may be other structures, as long as the hinge can be implemented.

In an exemplary embodiment, in order to better support and seal the base, the lower surfaces of the front side and the rear side of the cover plate are provided with protruding parts, the top of the inner side wall of the base is provided with a supporting part correspondingly combined with the protruding parts, and when the cover plate covers the base, the front side and the rear side of the base can be sealed and supported with each other.

Referring to fig. 9, which is a schematic structural view of an embodiment of the cover and the base in the present application, as shown in the figure, the lower surfaces of the front and rear sides of the cover respectively have a protrusion 94, and the top of the front and rear inner side walls of the base have a support portion 62, where the support portion 62 includes a step surface that is matched with the protrusion 94, and when the cover is covered on the base, the protrusion 94 is matched with the support portion 62, so as to enhance the stress on the front and rear sides of the base, thereby preventing the base from being deformed or damaged when being squeezed, and on the other hand, the base can perform a sealing function, thereby ensuring the suction efficiency.

In an exemplary embodiment, the cover and the base have corresponding snap-fit portions so that the cover can be snapped onto the base. The corresponding clamping parts may include one or more parts, that is, the cover plate and the base may have one or more pairs of corresponding clamping parts.

In an embodiment, referring to fig. 9, a third engaging portion 941 is disposed on the protruding portion 94, and a fourth engaging portion 621 corresponding to the third engaging portion 941 is disposed on an upper edge of the base. Here, the third engaging portion 941 is a protrusion, and the fourth engaging portion 621 is a groove, so as to engage the cover with the base. It should be understood that the fourth engaging portion on the front side cannot be directly observed due to the angle relationship in fig. 9, and is shown by a dotted line in fig. 9 to indicate the position and engaging relationship with the third engaging portion 941; correspondingly, the third engaging portion on the rear side is not shown because it is blocked at the view angle, but those skilled in the art should be able to obtain the positional relationship between the third engaging portion and the fourth engaging portion on the rear side through the positional relationship between the third engaging portion and the fourth engaging portion on the front side, and details thereof are not described herein.

In another embodiment, with reference to fig. 9, the cover plate has a fifth engaging portion 95 at each of two sides of the proximal end thereof, and the base has a sixth engaging portion 64 at the upper edge of the proximal end thereof corresponding to the fifth engaging portion 95. Here, the fifth engaging portion 95 is a protrusion, and the sixth engaging portion 64 is a groove, so as to achieve the engagement between the cover and the base. It should be understood that the sixth engaging portion on the front side cannot be directly observed due to the angular relationship in fig. 9, and is shown by a broken line in fig. 9 to indicate the position and engaging relationship with the fifth engaging portion 95.

In some embodiments, only the cover plate may be provided with the third engaging portion, and the base may be provided with the corresponding fourth engaging portion; the cover plate can be provided with a fifth clamping part and the base can be provided with a corresponding sixth clamping part; or a third clamping part and a fifth clamping part are arranged on the cover plate at the same time, and a corresponding fourth clamping part and a corresponding sixth clamping part are arranged on the base. Moreover, the bump and groove structure in this embodiment is merely an example of the engaging structure and is not limited thereto, and in practical applications, the bump and the groove may be replaced by other engaging structures, which is not described herein again.

In an exemplary embodiment, in order to avoid that the cover body loosens and cannot protect the suction nozzle in a non-use state, a matched clamping structure is arranged between the cover body and the base, so that the cover body is opened through the clamping structure to expose the suction nozzle in use, and the cover body is closed to cover the suction nozzle in non-use.

In an embodiment, the cover has first engaging portions at two sides thereof, and the base has seventh engaging portions at two side edges thereof, wherein the first engaging portions pass through the first air inlet and engage with the seventh engaging portions at two side edges of the base. The specific structure of the first engaging portion can be designed according to the engaging manner of the cover and the base. For example, the first engaging portion may be a protruding structure, and correspondingly, the cover plate has a seventh engaging portion, such as a slope or a groove, on the proximal side thereof for cooperating with the protruding structure. Alternatively, the first engaging portion may include a hook structure, and correspondingly, the seventh engaging portion includes a protrusion structure or the like engaged with the hook structure.

Please refer to fig. 6, which is a schematic structural diagram of a cover, a cover plate and a base in an embodiment of the present application. As shown in the figure, the two sides of the cover body 1 are provided with first clamping parts 11, the first clamping parts 11 are located at the front and rear sides of the inner wall of the cover body, and the first clamping parts 11 are provided with clamping hooks protruding towards the outer side of the cover body. Moreover, the front and rear side edges of the seat body 61 of the base 6 are respectively provided with a seventh engaging portion 67 corresponding to the first engaging portion 11, where the seventh engaging portion 67 is a groove structure, so that the hook structure of the first engaging portion 11 is engaged with the groove. Here, the first engaging portions 11 on both sides of the cover respectively pass through the first air inlet 92 to engage with both side edges of the base body 61 of the base.

In some embodiments, when the position of the first air inlet formed in the cover plate does not correspond to the position of the first engaging portion, so that the first engaging portion cannot pass through the first air inlet, the cover plate may also be provided with an opening corresponding to the first engaging portion, so that the first engaging portion can pass through the opening.

It should be noted that, the engaging structure of the cover and the base in this embodiment is only an example and is not limited, and in other embodiments, the cover may be engaged with other components, such as a cover plate, to implement the shielding of the suction nozzle, as long as the cover and the other components are provided with corresponding engaging structures, which is not described herein again.

In an exemplary embodiment, the cover may be opened by engagement of the button member in a state where the cover is engaged with the base. In one embodiment, the button member has a slope at the upper distal end, and the button member moves toward the capsule chamber in a pressed state to contact the slope with the first engaging portion and lift the first engaging portion upward to release the engagement between the cover and the base.

In one embodiment, please refer to fig. 7, which is a schematic structural diagram of the button member, the cover plate, the capsule chamber and the cover in one embodiment of the present application. Here, the structure of the base is not shown in order to clearly show the fitting relationship between the button member and the first engaging portion. As shown, the button 51 has a bevel 514 on its upper far side for cooperating with the first engaging portion 11 on the cover to open the cover. Specifically, in a state where the cover is fitted to the base, the first engaging portion of the cover is engaged with the seventh engaging portion of the base, and when the button 51 is pushed, the inclined surface 514 moves in the distal direction, and while the inclined surface 514 is in contact with the first engaging portion 11 and the button continues to move in the distal direction, the first engaging portion 11 is lifted upward and finally the engagement with the seventh engaging portion is released to open the cover.

In another embodiment, please refer to fig. 8a to 8c, which are schematic diagrams illustrating a matching structure of the button, the cover plate and the cover body in another embodiment, wherein fig. 8b is a schematic diagram of fig. 8a at another angle, and fig. 8c is an enlarged view of a portion a in fig. 8 b. Here, the structure and position of the button member is shown for clarity, so the capsule magazine structure is retained in the figures to show the positional relationship between the button member and the capsule magazine. As shown in fig. 8a, when the cover plate is further provided with a fifth engaging portion 95 for engaging with the base, the first engaging portion 11 can be disposed in the traveling direction of the inclined surface, and the fifth engaging portion 95 can be disposed outside the traveling direction of the inclined surface to avoid the influence. As shown in fig. 8b, since the fifth engaging portion 95 is not aligned with the button member slope, the slope only touches the first engaging portion 11 aligned with the slope during the distal movement of the button member to disengage the cover from the base.

In an exemplary embodiment, with continued reference to fig. 3, as shown, the nozzle body 21 includes a nozzle portion 211 and an operating portion 212. The operation portion 212 is used for operating when in use so as to enable the nozzle body to approach or separate from the cover plate. When the nozzle body is close to the cover plate, the nozzle body covers part of the cover plate, for example, at least the part covering the cover plate inlet, and exposes the first air inlet and the second air inlet on the cover plate, so that the suction channel 22 is communicated with the capsule inlet on the cover plate, and simultaneously, air flow can enter the base from the first air inlet and the second air inlet on the cover plate. As shown in fig. 3, the mouthpiece portion has an approximately flat elliptical structure adapted to the mouth (mouth) of a human body, so that a user can hold the upper portion of the mouthpiece with the mouth, thereby forming a negative pressure in the inhalation passage of the mouthpiece by inhaling in a state where the user's mouth wraps the upper portion of the mouthpiece.

The operation part 212 and the suction part 211 are integrally formed, and the operation part is matched with the cover plate and the suction part is matched with the mouth of a user during use, so that the operation part and the suction part have different shapes to better accord with the ergonomics. For this purpose, a transition surface is provided between the actuating part 212 and the suction part 211 in order to transition from the approximately flat oval configuration of the suction part 211 to an actuating part configuration which is matched to the shape of the cover plate.

In a possible embodiment, continuing to refer to fig. 3, the proximal end of the operating portion has a recessed structure 2121, thereby forming a surface height difference at the proximal end of the operating portion, which surface height difference facilitates a user to apply a force to open or close the nozzle during use, thereby facilitating the operation of the nozzle and ensuring the hygiene of the nozzle portion. In some embodiments, to prompt the user to operate the nozzle 2 through the recessed structure 2121, an operation mark including, but not limited to, text, patterns, colors, etc. may be further disposed at the recessed structure to prompt the user.

As shown in fig. 1c, the filter member 3 is sleeved on the bottom of the suction passage 22. In the present application, the sleeve is arranged to allow a larger diameter component to be sleeved on a smaller diameter component due to the difference in diameter between the two components. On the one hand, therefore, the filter element 3 needs to perform a filtering function to pass only the medicament powder through the inhalation passage; on the other hand, the filter member needs to be fixed to the bottom of the suction passage 22.

In one embodiment, please refer to fig. 2a, which is an exploded view of the filter member of the present application in one embodiment, as shown in the figure, the filter member 3 includes a mounting portion 31 and a screen portion 32, the screen portion 32 is used for blocking the fragments of capsule skin generated after the capsule is punctured so as to prevent them from entering the suction channel as much as possible, and the mounting portion is used for sleeving the bottom end of the suction channel 22.

It is noted here that in some cases, the blocking of the capsule debris is related to the diameter of the capsule debris and the filtration diameter of the filter element. For example, when the mesh diameter of the mesh portion is 0.8mm, then capsule debris having a diameter greater than 0.8mm may be blocked.

In an exemplary embodiment, in order to facilitate the combination of the inhalation channel and the capsule chamber to form an unobstructed airflow channel, the bottom of the inhalation channel is tubular, and the filter element is sleeved on the tubular structure at the bottom of the inhalation channel. The tubular structure may be a circular tube, a square tube, or a tube of other shape, as long as the powder medicine can pass through the tubular structure, but in consideration of inhalation efficiency, a circular tube, that is, a tubular structure having a circular cross section is used in the present embodiment. In a possible embodiment, the ratio of the cross-sectional area of the suction channel to the sum of the areas of the first and second airflow inlets is 1.

In an embodiment, the bottom surface of tubular structure with the installation department internal surface of filtering the piece has corresponding mounting structure, in order to incite somebody to action filter the piece set up in the tubular structure bottom to can make and firmly combine between filtering the piece and the tubular structure, guarantee availability factor and security.

In a possible embodiment, continuing to refer to fig. 3, a ring of ribs 221 is provided on the outer surface of the bottom end of the tubular structure 22 of the suction nozzle 2, and correspondingly, as shown in fig. 2a, the inner surface of the mounting portion 31 of the filter element has an annular groove 311 which is matched with the ribs, so that when the filter element is mounted on the tubular structure of the suction nozzle, the ribs 221 can be clamped in the annular groove 311.

It should be noted that, although the matching structure of the protruding rib and the annular groove is taken as an example in the present embodiment, the practical application is not limited thereto as long as the clamping effect of the filter element and the tubular structure can be achieved, for example, in other embodiments, one circle of the protruding rib in the above embodiments may be replaced by a plurality of protruding blocks formed on the outer surface of the tubular structure, and the annular groove may be replaced by a plurality of concave holes formed on the inner surface of the filter element mounting portion and corresponding to the plurality of protruding blocks. Moreover, the positions of the protruding rib and the annular groove, or the positions of the protruding block and the concave hole may also be interchanged, for example, the inner surface of the mounting portion of the filter element may be the annular groove and the outer surface of the bottom end of the tubular structure may be a circle of protruding ribs, or the outer surface of the bottom end of the tubular structure may be a plurality of concave holes and the inner surface of the mounting portion of the filter element may be a plurality of corresponding protruding blocks, etc., which are not described herein again.

In another embodiment, the screen part and the mounting part may also be an integrally formed structure, so as to facilitate manufacturing, production and assembly while taking filtering and fixing effects into consideration.

In an exemplary embodiment, continuing to refer to fig. 2a, to form the desired gas flow direction, the screen section includes a convex circular arc-shaped surface at the center and ribs at the periphery of the convex circular arc-shaped surface, and in possible embodiments, the convex circular arc-shaped surface and the ribs may be formed by stamping. In one embodiment, the screen section is made of stainless steel to facilitate stamping. In other embodiments, the screen part may be made of polymer material by a mold or 3d printing.

In some embodiments, in order to ensure the inhalation amount while blocking the capsule debris, the mesh diameter of the screen part is 0.6mm or less to 1mm, for example, 0.6mm or less, 0.7mm or less, 0.8mm or less, 0.9mm or less, 1mm or less, or the like; the wire diameter of the screen part is 0.1 mm-0.5 mm, such as 0.1mm, 0.2mm, 0.3mm, 0.4mm and 0.5mm; the ratio of the total area of the meshes of the screen part to the total area of the first airflow inlet and the second airflow inlet is 1:3-1:2.

It should be understood that the screen section includes a plurality of criss-cross wire structures to form a mesh shape, wherein the mesh of the mesh structure is a mesh, the wire diameter is the diameter of the wire structure, and the total mesh area of the screen section is the sum of the mesh areas. The mesh may be circular or square, for example, in an embodiment, the mesh may be a square with a side length of about 0.8mm, or the mesh may be a circular structure with a diameter of about 0.7mm, and so on, which are not described herein again.

The filter piece in this application can borrow characteristics such as circular arc convex surface, screen cloth line footpath and mesh area by means of and control the trend of flowing air current, also can avoid the patient to inhale the cracked capsule shell of large fragment when vigorously absorbing medicine powder simultaneously.

In an exemplary embodiment, the screen section and the mounting section may be integrated by ultrasonic welding.

Referring to fig. 2b and 2c, fig. 2b is a schematic structural view of a screen portion and a mounting portion before being welded in an embodiment, and fig. 2c is a schematic structural view of a screen portion and a mounting portion after being welded in an embodiment. As shown in fig. 2b and 2c, a circle of protrusions 312 is formed on the surface of the mounting portion during the ultrasonic welding process. Of course, in other embodiments, the screen section and the mounting section may be formed by injection moulding and forming the protrusions.

In an exemplary embodiment, the contact surface of the filter element and the capsule chamber has a matching end surface, so that in the attached state of the suction nozzle and the cover plate, the filter element can be pressed in the capsule inlet and tightly attached to each other to avoid air leakage during use. In some embodiments, the capsule inlet 91 is correspondingly combined with the screen part 32 so as to be tightly combined with the screen part to ensure the suction efficiency. Also, when the mounting portion of the filter element has the projection 312, the projection may help to enhance the sealing between the filter element and the cover plate.

In one possible embodiment, please refer to fig. 10, which is a schematic structural view of the filter and the cover plate of the present application in one embodiment. As shown in the figure, the outer surface of the lower part of the filter element is provided with a step-shaped structure formed by the transition of the shapes of the installation part and the screen part, correspondingly, the upper part of the inner surface of the capsule inlet 91 of the cover plate is provided with a shape matched with the step-shaped structure correspondingly, so that the filter element is tightly attached to the capsule inlet, and when the suction nozzle is attached to the cover plate, the whole screen part is positioned in the capsule inlet 91, therefore, when medicine powder is inhaled, the airflow can better form an ideal flow direction through the screen part under the negative pressure effect, and the inhalation efficiency of the medicine powder is improved.

In an exemplary embodiment, to further ensure the tight fit between the filter element and the cover plate, the filter element and the cover plate have corresponding engaging portions therebetween, so that the filter element can be engaged with the cover plate, and thus the mouthpiece and the cover plate can be relatively fixed by the filter element when the filter element is assembled at the bottom of the inhalation passage.

In a possible embodiment, the mounting portion of the filter member includes two second engaging portions located at the proximal end and extending downward, and the cover plate has two engaging holes corresponding to the two second engaging portions, respectively, so as to engage the suction nozzle with the cover plate. In one embodiment, the second engaging portion has a step-like structure to engage with the engaging hole.

Referring to fig. 1c, the proximal end of the filter element 3 is provided with two second engaging portions 313, and the second engaging portions 313 are engaged with the two engaging holes at the proximal end of the cover plate. Referring to fig. 13, which is a schematic view of the suction nozzle, the filter element and the cover plate of the present application in one embodiment, as shown in the figure, when the filter element is fastened to the bottom of the suction channel of the suction nozzle, the suction nozzle can be fastened to the cover plate 9 through the second fastening portion on the filter element, so that the filter element is more attached to the capsule inlet of the cover plate, and the suction efficiency of the air flow is ensured.

It should be noted that the step-shaped structure and the clamping hole in this embodiment are only examples of the clamping manner between the filter element and the cover plate, and are not limited thereto, and in practical applications, the second clamping portion may also be other structures capable of being clamped in the clamping hole, which is not described herein again.

In an exemplary embodiment, the cover plate is provided with a plurality of air holes at the opposite side of the cover plate to the filter element, so as to form air flow when negative pressure is generated in the chamber, wherein the number of the air holes can be one or more. In some embodiments, the opposite surface of the cover plate to the filter member is a capsule inlet, and the air holes may be uniformly distributed at the capsule inlet, or may be irregularly distributed at the capsule inlet.

Referring to fig. 14 in combination with fig. 13, fig. 14 is a schematic structural diagram of another embodiment of the cover plate of the present application, as shown in fig. 14, 3 air holes 96 are uniformly distributed at the capsule arrangement inlet of the cover plate, and in a possible embodiment, the diameter of the air holes is not greater than 1mm. In one embodiment, the filter element is disposed at the bottom of the suction channel of the suction nozzle, the suction nozzle is located above the cover plate so that the filter element is attached to the capsule inlet of the cover plate, and the cover plate covers the base. When a negative pressure is created in the inhalation passage, air flows into the base from the first and second air flow inlets, respectively, wherein a portion of the air flow will enter the capsule chamber and a small portion will pass through the air holes 96, as shown in fig. 13. In some embodiments, the air flow through the air holes 96 and the incoming air within the capsule chamber may help create turbulence to cause the capsule to vibrate and/or rotate within the capsule chamber, thereby facilitating the release of the powdered medicament within the capsule. In some embodiments, when the cover plate is provided with the air holes 96, the difference between the air inflow and the air inflow of the cover plate without the air holes is about ten percent, so that the air flow is ensured and the ideal air flow direction is generated.

The cover plate and the capsule bin can be manufactured in a split mode and then are connected into a whole in a matched mode, and the cover plate and the capsule bin can also be of an integrated forming structure.

In an exemplary embodiment, the chamber of the capsule magazine comprises a main chamber having a diameter greater than the transverse cross-sectional diameter of the capsule and smaller than the longitudinal cross-sectional diameter of the capsule in order to maintain the capsule in an upright condition in the main chamber for piercing by the piercing assembly. Please refer to fig. 11, which is a schematic structural diagram of a cover plate, a capsule bin and a capsule according to an embodiment of the present application. As shown, the lateral diameter D of the primary chamber 421 ₁ Larger than the transverse cross-sectional diameter D of the capsule 8 ₃ So as to enable the capsule 8 to enter the main chamber and the transversal diameter D of the main chamber 421 ₁ Smaller than the longitudinal cross-sectional diameter D of the capsule 8 ₂ So as to keep the capsule 8 in an upright condition in the main chamber 421. In a possible embodiment, the ratio of the transverse diameter to the longitudinal diameter of the primary chamber is 1:2 to 1:3. In some embodiments, to ensure gas flow through the main chamber, the ratio of the cross-sectional area of the main chamber to the sum of the areas of the first and second gas flow inlets is 1:2-1.5.

It should be noted that, in the present embodiment, there is no limitation on the size of the capsule, the capsule may be any size of capsule, and the diameter of the main chamber may be configured to match the size of the capsule in order to adapt to the size of the capsule. The size of the capsule is usually related to the amount of the drug to be administered, i.e. when the amount of powder is large, the capsule size is designed to be large, and when the amount of powder is small, the capsule size is designed to be small.

In one embodiment, the capsule 8 is generally designed to have a transverse cross-sectional diameter D3 of 5 to 6mm and a height, i.e., a longitudinal cross-sectional diameter D2 of 15 to 16mm, in consideration of the amount of powdered medicament currently used, such as tiotropium bromide, indacaterol, etc., as mentioned above. Also, in some embodiments, since the capsule is assembled by two shells, i.e. an upper shell and a lower shell, please refer to fig. 12, which shows a structural schematic diagram of the capsule in one embodiment of the present application, the outer shell of the capsule is assembled by an upper shell 8a and a lower shell 8b, and the sum of the longitudinal section diameters of the upper shell 8a and the lower shell 8b is generally designed to be 16-17 mm.

In an exemplary embodiment, with continued reference to fig. 11, the bottom of the chamber 42 of the capsule chamber is provided with a sub-chamber 422 communicated with the main chamber 421, and the sub-chamber 422 is used for providing an air inlet passage for the main chamber 421. The bottom end of the sub-chamber 422 is provided with an air inlet, so that the capsule bin can be communicated with the inner space of the base body of the base after being clamped on the base body of the base to form an air inlet channel, and a gap is formed between the air inlet at the bottom end of the sub-chamber and the bottom surface of the base. And, in order not to drop the capsule from the main chamber to the sub-chamber, the diameter D of the sub-chamber ₄ Smaller than the transverse cross-sectional diameter D of the capsule ₃ . In some embodiments, in order to ensure the gas inlet amount in the cavity, the ratio of the cross-sectional area of the cavity inlet to the total area of the first gas flow inlet and the second gas flow inlet is 1:8-1:7.

In an exemplary embodiment, the chamber of the capsule cartridge comprises a mounting structure cooperating with the piercing assembly such that the piercing assembly remains connected to the capsule cartridge in the non-use state and is movable relative to the capsule cartridge to pierce a capsule in the capsule cartridge in the use state. The mounting structure comprises a mounting plate, the mounting plate and the cavity can be of an integrated structure, and a clamping groove and a tube part, wherein the clamping groove is used for enabling the button part of the piercing assembly to move relative to the capsule bin and not to be separated from the capsule bin, and the tube part is used for limiting the piercing direction of the piercing needle of the piercing assembly. In some embodiments, in order to force the piercing assembly to automatically return to the initial position after piercing the capsule during use, the piercing assembly further comprises a return mechanism, for example, but not limited to, a spring or other elastic element; and, the position department that corresponds canceling release mechanical system on the mounting panel is equipped with the portion of leaning on to play the effect that the position of restriction canceling release mechanical system guaranteed its normal work. In some embodiments, the button member may also be provided with a mounting block for mounting the reset mechanism, so as to achieve a more secure connection. Wherein, the arrangement positions of the clamping groove, the abutting part and the pipe part can be determined according to the structure of the piercing assembly. For example, when the piercing assembly is movably connected with the mounting plate through the left side and the right side of the button member, the piercing assembly is matched with the capsule in the capsule bin through the two piercing needles arranged up and down, and the reset mechanism is arranged between the two piercing needles, the clamping grooves can be correspondingly arranged on the symmetrical left side and the symmetrical right side of the mounting plate, the abutting portion can be arranged between the symmetrical clamping grooves, and the two pipe portions corresponding to the two piercing needles can be respectively arranged on the upper side and the lower side of the abutting portion.

In one embodiment, the number of lancets in the lancing assembly can be one or more, and the proximal end of each lancet is cooperatively connected with the button member, such as by an interference fit connection or the like. The position and the number of the tube parts on the mounting plate correspond to the position and the number of the felting needles. After mounting the piercing assembly to the capsule magazine, the piercing needles may be arranged in corresponding tube portions on the mounting plate, i.e. distal to each piercing needle in each corresponding tube portion, and when a force is applied to the button member, the piercing needles may be moved along the tube portions to pierce a capsule located in the chamber after reaching the chamber.

The puncture needle is a component for puncturing the capsule, and the puncture needle is not necessarily an elongated structure, but may also be a thin sheet-like structure. For example, the lancet can also be designed flat like a blade structure, and correspondingly, the tube portion of the mounting plate can be adapted to a flat tube structure to allow the blade-like lancet to move within its tube, in which case the lancet cuts the capsule in a transverse manner, either as a large opening or directly in half or more, when it pierces the capsule.

In a possible embodiment, to ensure that each needle is functional and to increase the efficiency of the escape of the medicament, the spacing between the two needles that are furthest from each other of the needles should be less than the height of the capsule and greater than half the height of the capsule. For example, when the number of the puncture needles is two, the distance between the two puncture needles should be less than the height of the capsule and more than half of the height of the capsule, for example, when the puncture needles puncture the capsule, the wall breaking position of the capsule is just at the transition position between the main part and the top part at the two ends of the capsule. In this embodiment, the distance between the holes formed in the capsule after the piercing of the capsule by the piercing needles is 3/5 to 4/5 of the height of the assembled capsule.

The arrangement of the needles can be configured according to the placement direction of the capsule and the number of the needles. For example, when the needles are one, they can be arranged at a position corresponding to the centre of the capsule; when the number of the pricking pins is two and the capsule is vertically placed, the two pricking pins can be arranged up and down; when the two pricking pins are arranged and the capsule is transversely placed, the two pricking pins can be arranged left and right; when the number of the pricker is three or more, the prickers can be on the same straight line or not. It should be understood that the arrangement of the needles is merely exemplary and not restrictive, and can be adjusted according to specific requirements in practical applications, and will not be described herein.

It should be noted that, in the above embodiment, the capsule chamber is designed to be a vertical structure, so that the capsule is placed in the capsule chamber in a vertical state. In other possible embodiments, the capsule magazine may also be designed in a transverse configuration so that the capsules are placed in the capsule magazine in a transverse position, and accordingly the piercing needles in the piercing assembly and the tube sections on the mounting plate are arranged side to side so as to match the direction of placement of the capsules in order to pierce them.

In an exemplary embodiment, please refer to fig. 15, which shows a schematic structural diagram of the lancet needle in an embodiment of the present application, as shown in the figure, in order to facilitate the lancet needle to puncture the capsule and avoid the generation of capsule debris as much as possible, the tip portion of the lancet needle 52 has a bevel, the position of the tip of the lancet needle is an eccentric design, the tip of the lancet needle is formed by three inclined planes intersecting at the same point, and the tip of the lancet needle is not coincident with the extension line of the axial lead of the lancet needle, i.e., the tip point of the lancet needle is not on the same line with the axial lead of the lancet needle. When the capsule shell is pierced, fragments at the broken part of the capsule are not easy to fall off from the capsule, thereby fundamentally avoiding the generation of the fragments of the capsule and ensuring the safety and the comfort of the inhalation process. At the same time, the structure can also make the medicine powder be effectively released in the process of inhalation. In some embodiments, the diameter of the lancet needle can be designed to be 1mm to 2mm.

In one embodiment, in order to facilitate the movable connection of the piercing assembly to the mounting plate, the button member of the piercing assembly includes a pressing portion and a movable connecting portion, the pressing portion and the movable connecting portion are of an integral structure, and a distal end of the movable connecting portion has a limiting portion cooperating with the clamping groove, so that the piercing assembly can move relative to the capsule chamber without departing from the mounting plate.

In a possible implementation manner, please refer to fig. 16, which is a schematic structural diagram of the button in the present application in an embodiment, as shown in fig. 16, the button 51 includes an integrally formed pressing portion 510 and a movable connecting portion, in this embodiment, the movable connecting portion includes extending arms 511 extending distally from two sides of the button 51, a protruding hook portion 512 is provided at a distal end of the extending arms 511 as a limiting portion, and the hook portion and the extending arms are of an integral structure.

Correspondingly, please refer to fig. 17, which is a schematic structural diagram of the mounting structure in the present application in an embodiment, as shown in the figure, two slots 441 are formed on the mounting plate 44, the positions of the two slots 441 correspond to the position of the extension arm 511, and the width of the slot 441 is slightly greater than the width of the extension arm 511, so that the extension arm 511 can slide in the slot. Meanwhile, the width of the clamping hook part 512 added with the extension arm 511 is larger than that of the clamping groove 441, so that the extension arm cannot be separated from the mounting plate when sliding in the clamping groove 441.

In some cases, please refer to fig. 18a and 18b, which are schematic structural views of the button member in another embodiment of the present application, wherein,fig. 18b is an enlarged view of the portion G of fig. 18a from another viewing angle. To further facilitate assembly of the piercing assembly to the mounting plate 44, as shown in fig. 18b, the hooking portion 512 of the button member 51 has a slope s, the distance between the slope s and the extension arm 511 increases from the far side to the near side, please refer to fig. 17 in combination with fig. 18b, the notch has a shape corresponding to the hooking portion at the side to provide a deformation space for the extension arm, and the minimum width h at the slope is _e1 Is less than the width h of the clamping groove 441 _g Maximum width h at slope _e2 Approximately equal to the width h of the card slot 441 _g . Here, as shown in fig. 18b, the minimum width h at the slope _e1 Including the combined width of the distal side of the hook and the distal side of the extension arm, the maximum width h at the bevel _e2 Including the combined width of the proximal side of the hook and the proximal side of the extension arm. Based on this structural design, when installed, the distal side of the extension arm 511 is aligned with the slot 441 on the mounting plate 44 due to the minimum width h at the bevel _e1 Is less than the width h of the clamping groove 441 _g The extension arm 511 can pass through the clamping groove, and along with the width increase of inclined plane department, the inclined plane pastes tight clamping groove 441 border gradually, the clamping groove 441 will exert pressure to the inclined plane after continuing the application of force, the extension arm borrows and produces slight elastic deformation so that continue to move to the distal side by self material characteristic, at last when whole trip portion 512 passes behind the clamping groove 441, the extension arm returns to initial state and will pierce through the trip portion 512 the subassembly spacing, so that pierce through the subassembly can be for the motion of capsule storehouse but not break away from the mounting panel.

It should be noted that, the structure of the limiting portion in this embodiment is only an example and not a limitation, and in practical applications, the limiting portion may also be another structure as long as the button can pass through the mounting plate and limit it, for example, the hook portion in fig. 18a and 18b may also be replaced by a plurality of small hooks distributed at the far side of the extension arm as the limiting portion.

In some cases, since the spike is located in use within the tube portion of the mounting plate, the position of the spike relative to the capsule within the capsule magazine cannot be clearly seen in use and it is not possible to directly determine whether the capsule has been adequately punctured. Referring to FIG. 21, a schematic view of the lancet and button of the present application is shown in one embodiment. As shown, in some embodiments, the distal end of the spike 52 may be substantially perpendicular to the distal end of the movable connection 511, such that when the button member is assembled to the capsule cartridge, the user may sense the distal position of the spike by the position of the distal end of the movable connection of the button member when the piercing assembly is pressed.

In one embodiment, please refer to fig. 19 in combination with fig. 17, wherein fig. 19 is a schematic structural diagram of a piercing assembly in accordance with the present application in yet another embodiment. Referring to fig. 19, the number of the lancet needles 52 is two, and the two lancet needles 52 are arranged in an up-down manner, and are located between the front and rear extension arms 511, and are connected with the button member 51 in an interference fit manner through the near side. Referring to fig. 17, two tube portions 443 are provided on the mounting plate 44 of the capsule magazine corresponding to the two piercing needles, so that the two tube portions 443 are also arranged up and down on the mounting plate 44, the tube portions 443 communicating with the chamber 42 of the capsule magazine 4. After mounting the piercing assembly 5 to the capsule magazine, the lancet needles are arranged through the tube portions 443, i.e. the lancet needles 52 are located distally in both tube portions 443, and when a force is applied to the button member 51, the lancet needles 52 can be moved along the tube portions 443 to pierce the capsules located in the chamber 42 after extending into the chamber. By penetrating is meant that the lancet has a diameter that is smaller than the diameter of the tube portion so as to pass through the hollow portion of the tube portion, and that a portion of the lancet, such as the distal end of the lancet, can be located within the tube portion in an initial state (i.e., in a state in which no force is applied to operate the button member) in order to facilitate movement of the lancet along the tube portion.

In order to force the piercing assembly to automatically return to its initial position after piercing the capsule during use, the piercing assembly further comprises a return mechanism 53, the return mechanism 53 including, by way of example and not limitation, a spring or the like. And, the mounting plate 44 is provided with an abutting portion 442 at a position corresponding to the reset mechanism 53, so as to limit the position of the reset mechanism and ensure the normal operation thereof. Here, the abutting portion 422 may be a mounting seat for fixing the return mechanism 53, for example, when the return mechanism is a spring, the abutting portion 422 may be a spring mounting seat protruding toward the proximal side so as to sleeve the distal side of the spring on the mounting seat. Here, the abutting portion 442 is provided at the center of the mounting plate, that is, between the left and right card slots 441 and between the upper and lower tube portions 443, in consideration of space utilization efficiency of the mounting plate. Referring to fig. 20, which shows a schematic structural diagram of a button member in the present application in a further embodiment, as shown in the figure, a mounting block 513 is disposed on a position of the button member 51 corresponding to the reset mechanism, where the mounting block 513 is a protrusion with an approximately "cross" shape structure so as to mount the reset mechanism thereon, and of course, in other embodiments, the reset mechanism may be disposed at other positions as long as the button member can be reset after being stressed. The structure of the abutting portion and/or the mounting block can also be designed according to actual requirements, and is not limited to the outwardly protruding structure, for example, the abutting portion and/or the mounting block can also be a recessed structure, such as a groove, etc., so as to mount the reset mechanism therein.

In an exemplary embodiment, continuing to refer to fig. 9, an opening 613 is provided at the proximal end of the base to provide space for installation and movement of the piercing assembly through the opening 613 after the capsule cartridge is assembled into the base, so that the piercing assembly can be moved along the capsule cartridge under force.

In an exemplary embodiment, in order to observe the capsule state in the capsule chamber during operation, the base further comprises a transparent window, the transparent window is installed on the base body, and meanwhile, the chamber of the capsule chamber is also made of transparent materials, so that the capsule state in the chamber can be observed through the transparent window and the transparent chamber during use, and the wall breaking state of the capsule can be observed during puncturing.

Wherein, the position of transparent window setting on the base can be designed according to actual demand, for example transparent window can set up both sides around the base, perhaps transparent window also can be located the base distal end and extend to both sides around the base, as long as can see the capsule state in the capsule storehouse clearly through the window can.

In one embodiment, please refer to fig. 22, which is a schematic structural diagram of the base according to an embodiment of the present application, as shown in the figure, the transparent window 63 is located on one side above the distal end of the base 61, and both sides of the transparent window respectively extend to the front and rear sides of the base seat body, i.e., the upper portion of the distal side, the upper portion of the distal end of the front side, and the upper portion of the distal end of the rear side of the base seat body are transparent, so as to facilitate observation of the state of the capsule in the capsule chamber. The transparent window can be integrally formed on the base body, and can also be split and mounted on the base body. In other embodiments, the base may be made of a transparent material as a whole.

In an exemplary embodiment, a flow restriction plate is further disposed in the base, and an air flow guide hole is disposed on the flow restriction plate to restrict the magnitude of the air flow and control the air intake direction of the air flow. In a possible embodiment, the flow restriction plate is arranged at the far side in the base so as to simplify the structural design due to the requirement of providing a movement space of the button member at the near side of the base. The number of the airflow guide holes can be configured into one or more according to actual requirements, and similarly, the shapes and the opening positions of the airflow guide holes can also be designed according to parameters such as expected airflow direction and flow rate.

In an embodiment, please refer to fig. 25, which is a schematic structural diagram of the base of the present application in another embodiment, as shown in the figure, a flow restriction plate 66 is disposed in the seat body of the base 6, and two air flow guide holes are symmetrically disposed on the flow restriction plate. When negative pressure is generated in the suction channel, the air flow entering from the second air inlet channel enters the capsule bin after being controlled by the air flow of the air flow guide hole. Here, the air flow guide hole is an elongated opening, so that the air flow in the second air intake passage is merged at the two air flow guide holes. In a possible embodiment, the area of each airflow guide hole may be determined according to parameters such as the areas of the first airflow inlet and the second airflow inlet or the total intake air amount. In one embodiment, the area of each air flow guide hole can be 20-35 mm ² E.g. 20mm ² 、21mm ² 、22mm ² 、23mm ² 、24mm ² 、25mm ² 、26mm ² 、27mm ² 、28mm ² 、29mm ² 、30mm ² 、31mm ² 、32mm ² 、33mm ² 、34mm ² 、35mm ² And the like.

In an exemplary embodiment, continuing to refer to fig. 1b, there is shown a schematic view of the inhalation device of the present application in a further embodiment, which comprises a cover 1, a mouthpiece 2, a filter 3, a cover 9, a capsule chamber 4, a piercing assembly 5, and a base 6. Wherein the cover 1 is coaxially hinged distally to the base 6 by a second hinge (19, 69b), and the mouthpiece 2, the cover 9, and the base 6 are coaxially hinged distally by a first hinge (29, 99, 69 a).

The suction nozzle 2 is characterized in that a suction opening portion matched with the mouth of a human body and an operation portion convenient to operate are arranged above a suction nozzle body of the suction nozzle, the suction opening portion is used for being matched with the mouth of the human body so that a user can suck powder medicine into a respiratory tract through the suction nozzle, a concave structure is arranged at the near end of the operation portion for operation in use, and the suction nozzle body is convenient to approach or separate from a cover plate and keep the cleanliness of the suction opening portion. Suction channel bottom of suction nozzle 2 is the tubular structure, and filter 3 and establish promptly on this tubular structure, filter 3 including be used for installing in suction channel's installation department and for filterable screen cloth portion, filter the installation department of 3 and cooperate through the recess of internal surface and the round rib that inhales channel lower part surface to will filter 3 cards in suction channel bottom. The sieve net portion of filtering piece adopts stainless steel and through stamping forming with the convex surface that forms to be located the center and be located the flange on convex surface border, the mesh size diameter less than or equal to 0.6mm to 1mm of sieve net portion, just the line footpath diameter of sieve net portion is 0.1mm ~ 0.5mm. The screen part and the mounting part are welded into a whole through ultrasonic wave, and a circle of bulges are formed on the surface of the mounting part.

The cover plate 9 is positioned below the suction nozzle and is provided with a capsule inlet correspondingly combined with the filter element, two first air inlets 92 are arranged on the near side of the cover plate 9, two second air inlets 93 are arranged on the far side of the cover plate, when the cover plate is clamped on the base, a first air inlet channel from the first air inlets to the cavity and a second air inlet channel from the second air inlets to the cavity are formed, and the total area of the first air inlets and the second air inlets is 74mm ² . The mounting part of the filter member comprises two second parts which are positioned at the near end and extend downwardsThe cover plate is also provided with clamping holes respectively corresponding to the two second clamping parts, so that when the filter piece is arranged on the suction channel of the suction nozzle, the suction nozzle is clamped with the cover plate. The opposite surface of the filter piece and the cover plate capsule inlet is provided with end surfaces with matched shapes, so that the filter piece can be pressed in the capsule inlet and tightly attached to the capsule inlet in a clamping state of the suction nozzle and the cover plate, and airflow leakage is avoided. The cover plate is uniformly provided with 3 air holes on the opposite surface of the cover plate and the filter piece, and the air holes are used for forming air flow when negative pressure is generated in the cavity. Here, although the mounting portion has a circle of protrusions, a small amount of air flow can penetrate through the gap between the protrusions and the cover plate in use.

The capsule magazine 4 is located below the cover plate 9 and comprises a chamber 42, wherein the chamber 42 is in turn divided into a main chamber and a sub-chamber. The capsule can be placed into the main chamber through the capsule placement port on the cover plate, and because the diameter of the main chamber is larger than the transverse section diameter of the capsule and smaller than the longitudinal section diameter of the capsule, and the diameter of the auxiliary chamber is smaller than the transverse section diameter of the capsule, the capsule is kept in a vertical state in the main chamber so as to be pierced by the piercing component. The upper part of the sub-chamber is communicated with the main chamber, the lower part of the sub-chamber is also provided with an opening, and a gap is arranged between the sub-chamber and the inner bottom of the base, so that external air flow can enter the capsule bin.

The piercing assembly 5 is held in positional relationship with the capsule magazine 4 by a mounting plate. The puncturing component 5 comprises a button component, two puncturing needles and a resetting mechanism. The button piece comprises a pressing portion and movable connecting portions located on two sides of the far end of the pressing portion, clamping grooves are correspondingly formed in positions, corresponding to the movable connecting portions, of the mounting plate, and limiting portions on the movable connecting portions can limit the button piece in the clamping grooves so that the button piece can move along the clamping grooves but cannot be separated from the clamping grooves. The reset mechanism is positioned between the movable connecting parts on the two sides, a leaning part is arranged on the mounting plate corresponding to the reset mechanism, one side of the reset mechanism is connected with the button piece in a matched mode, and the other side of the reset mechanism is installed on the leaning part to help the button piece to return to the initial position after the button piece is pressed. The near ends of the two puncture needles are respectively fixed on the button member and are arranged up and down, and the positions corresponding to the two puncture needles on the mounting plate are respectively provided with a pipe part correspondingly, so that after the puncture assembly is mounted on the mounting plate of the capsule bin, the two puncture needles are respectively positioned in the corresponding pipe parts, and as the pipe parts are communicated with the main chamber, when the button member is pressed, the button member can drive the puncture needles to lead to the main chamber through the pipe parts to puncture the capsule.

The sharp end of the pricking pin is formed by intersecting three inclined planes at the same point, the sharp end is not coincident with the extension line of the axial lead of the pricking pin, and the diameter of the pricking pin is 1-2 mm, so that the pricking pin can puncture the capsule and can avoid generating capsule scraps as far as possible. The distal end of the puncture needle and the distal end of the movable connecting part are positioned on the same vertical line, so that when the puncture assembly is pressed, a user can sense the distal end position of the puncture needle through the distal end position of the movable connecting part of the button member under the state that the button member is assembled in the capsule cabin.

The base 6 comprises a seat body 61, the interior of the seat body 61 is a hollow structure for accommodating the chamber 42 of the capsule chamber, and an opening is provided at the near side of the seat body 61, so that after the capsule chamber is assembled in the base, a moving space is provided for the piercing assembly through the opening 613, and the piercing assembly can move along the capsule chamber under a force application state. The lower surfaces of the front side and the rear side of the cover plate are provided with convex parts; and a supporting part correspondingly combined with the bulge part is formed at the top of the inner side wall of the base and used for realizing sealing and mutual supporting with the front side and the rear side of the base under the state that the cover plate covers the base. The convex part is provided with a third clamping part, and the upper side edge of the base is provided with a fourth clamping part corresponding to the third clamping part so as to clamp the base with the cover plate; and the two sides of the cover plate are respectively provided with a fifth clamping part, and the upper side edge of the base is provided with a sixth clamping part corresponding to the fifth clamping part, so that the clamping between the base and the cover plate is enhanced. The far side of the base is further provided with a third airflow inlet, the third airflow inlet is communicated with the second airflow inlet in the state that the cover plate is combined with the base, and when negative pressure is generated in the suction channel, a second air inlet channel from the third airflow inlet and the second airflow inlet to the cavity can be formed, so that the air inflow is expanded. The above-mentionedOne side of the base close to the far end is provided with a current limiting plate provided with two air flow guide holes, the two air flow guide holes are symmetrically arranged on the current limiting plate, and the area of each air flow guide hole is 28mm ² The air flow control device is used for limiting the size of the air flow and controlling the air inlet direction of the air flow.

The base is still including installing in transparent window on the pedestal, the cavity in capsule storehouse has transparent wall, transparent window is located the base distal end and extends to both sides around the base for see through under the user state the capsule state in the capsule storehouse is observed to the base.

When the cover body is closed, the two first clamping parts respectively penetrate through the two first air inlets on the front side of the cover plate and are clamped with the edges of the two sides of the base body of the base. The button piece moves towards the capsule bin under the pressing state so that the inclined surface is in contact with the first clamping part and the first clamping part is lifted upwards to release the clamping of the cover body and the base.

Here, in order to secure the suction efficiency, the areas of the first air inflow ports are each 9mm ² The area of the pipe orifice of the tubular structure is 18.9mm ² The total mesh area of the screen part is 30mm ² The cross-sectional area of the main chamber is 47.2mm ² The cross-sectional area of the chamber inlet is 10.4mm ² 。

When the puncture needle is used, firstly, the cover body 1 and the suction nozzle 2 are opened, the capsule is placed into the main cavity through the capsule placing opening 91 on the cover plate 9, then the suction nozzle 2 and the cover body 1 are closed, the button piece is pressed, the button piece drives the puncture needle to enter the main cavity along the tube part to puncture the capsule, and an operator can sense the far end position of the puncture needle through the far end position of the movable connecting part of the button piece. When the operator cancels the force application to the button member, the reset mechanism resets the button member to the initial position.

Then, the user opens the cover body and sucks air with the mouth portion over the suction nozzle. Referring to fig. 26, which is a schematic view of the air flow direction of the inhalation device in one embodiment of the present application, as shown in the figure, under the action of the negative pressure generated in the mouthpiece 2, the external air flows through the first air inlet channel and the second air inlet channel into the main chamber 421 through the bottom of the sub-chamber 422, and the air holes provided at the capsule inlet of the cover plate generate air flow to help the capsule to vibrate and rotate so as to release the medicine powder in the capsule. Due to the structural design of the screen part, airflow which is favorable for powder to escape is generated in the main cavity, the powder enters the suction channel of the suction nozzle 2 through the screen part, the capsule scraps are blocked outside the screen part, and the powder in the suction channel is sucked into the body of a user.

And finally, opening the suction nozzle to clean the capsule shell, the scraps and the like in the capsule bin, and/or cleaning and airing the capsule shell, the scraps and the like, and then covering the suction nozzle and the cover body for subsequent use.

The suction device in this application is through two side designs of admitting air to put many places designs such as gas pocket, restrictor plate of entrance through sieve portion structure, capsule, make suction device produce ideal air current trend under the user state, the capsule in the help capsule storehouse produces vibration and/or rotation in order to release medicine powder, guarantees suction efficiency. In addition, the suction device can open the cover through the cooperation of the button piece, the cover body and the base, and is convenient to use. In addition, the double-shaft connection of the suction device, the supporting structure matched between the cover plate and the base and other parts are designed to ensure the service life of the product; the concave structure of the operating part of the suction nozzle can ensure the sanitary cleanliness in the using process, the position relation between the puncture needle and the movable connecting part is convenient for sensing the puncture position, the operation is convenient, and the design accords with the ergonomics.

The above embodiments are merely illustrative of the principles and utilities of the present application and are not intended to limit the present application. Any person skilled in the art can modify or change the above-described embodiments without departing from the spirit and scope of the present application. Accordingly, it is intended that all equivalent modifications or changes which can be made by those skilled in the art without departing from the spirit and technical concepts disclosed in the present application shall be covered by the claims of the present application.

Claims

1. An inhalation device, comprising:

the suction nozzle comprises a suction nozzle body and a suction channel formed in the suction nozzle body;

the filter element is arranged at the bottom end of the suction channel and used for blocking capsule scraps generated after the capsule is punctured;

the cover plate is arranged below the suction nozzle and is provided with a capsule placing port correspondingly combined with the filter element, and the near side and the far side of the cover plate are respectively provided with a first airflow inlet and a second airflow inlet;

the capsule bin is positioned below the cover plate and is provided with a cavity used for containing the capsule in a use state, and the cavity is communicated with the capsule inlet of the cover plate;

the piercing assembly comprises a button part and a piercing needle which are movably arranged on one side of the capsule bin, and the button part moves towards the capsule bin under a pressing state to drive the piercing needle to pierce the capsule in the capsule bin;

a base including a seat body for accommodating the capsule cartridge and a part of the piercing member, and forming a first air inlet passage from the first air inlet to the chamber and a second air inlet passage from the second air inlet to the chamber in a state where the cover plate is covered on the base;

the cover body covers the suction nozzle in a clamping state with the base;

when negative pressure is generated in the cavity, the air flows of the first air inlet channel and the second air inlet channel form confluence at the bottom end of the cavity and enter the cavity, and the medicine powder in the punctured capsule in the cavity enters the suction channel through the capsule placing port and the filter element.

2. The inhalation device according to claim 1, wherein the base, the cover plate and the distal end of the mouthpiece are coaxially connected by a first hinge, the cover is coaxially connected to the distal end of the base by a second hinge, and the first hinge and the second hinge are not coaxial.

3. The inhalation device according to claim 1, wherein the cover has first engaging portions at two sides thereof, and the first engaging portions pass through the first air inlet to engage with two side edges of the base.

4. The inhalation device according to claim 1, wherein the tip of the lancet is formed by three inclined planes intersecting at the same point, and the tip is not coincident with an extension of the axial line of the lancet.

5. An inhalation device according to claim 1 or 4, wherein the needles have a diameter of 1mm to 2mm.

6. The inhalation device according to claim 1, wherein the number of the needles is two and the needles are arranged in an upper and lower manner, and the distance between the two needles arranged in the upper and lower manner is smaller than the height of the capsule and larger than half of the height of the capsule.

7. The inhalation device according to claim 1, wherein said mouthpiece body comprises:

the operation part is positioned at the near side of the suction nozzle body and is used for operating when in use so as to enable the suction nozzle body to be close to or separated from the cover plate;

and the suction port part is integrally formed with the operation part, and is provided with the suction channel and the outline which is suitable for the mouth part of the human body.

8. The inhalation device according to claim 7, wherein said proximal end of said operating portion has a recessed configuration.

9. The inhalation device according to claim 8 wherein said recessed structure has an operating indicia thereon.

10. An inhaler according to claim 1, wherein the ratio of the cross-sectional area of the suction passage to the sum of the areas of the first and second airflow inlets is from 1.

11. The inhalation device according to claim 1, wherein said filter member comprises a mounting portion for mounting to said inhalation passage, and a screen portion for filtering.

12. The inhalation device according to claim 11, wherein the bottom of the inhalation passage is tubular in configuration, and the outer surface of the bottom end of the tubular configuration and the inner surface of the mounting portion of the filter element have corresponding mounting structures for mounting the filter element to the bottom end of the tubular configuration.

13. The inhalation device according to claim 11, wherein the screen section comprises a convex surface in the shape of a circular arc at the center and ribs at the peripheral edge of the convex surface in the shape of a circular arc.

14. The inhalation device according to claim 11 wherein the mesh diameter of the screen section is 0.6mm to 1mm or less.

15. An inhalation device according to claim 11 characterised in that the wire diameter of the screen section is 0.1mm to 0.5mm.

16. The inhalation device according to claim 11 wherein the ratio of the total amount of mesh area of the screen section to the total amount of area of the first and second gas stream inlets is 1:3 to 1:2.

17. An inhalation device according to claim 11 characterised in that the screen section is of stainless steel.

18. An inhalation device according to claim 11 characterised in that the screen section and the mounting section are ultrasonically welded together and thereby form a ring of protrusions on the surface of the mounting section.

19. An inhalation device according to claim 1 or 11, characterised in that the opposite faces of the filter element and the cover plate have end faces which are shaped to fit closely together.

20. The inhalation device according to claim 19, wherein the cover plate has a plurality of air holes formed therein at a position opposite to the filter member to assist turbulence in the chamber when a negative pressure is generated in the chamber to cause the capsule to vibrate and/or rotate.

21. The inhalation device according to claim 11, wherein the mounting portion comprises two second engaging portions extending downward and located at the proximal end, and the cover plate has two engaging holes corresponding to the two second engaging portions respectively, for engaging the suction nozzle with the cover plate.

22. The inhalation device according to claim 1, wherein the lower surfaces of both sides of the front and rear of said cover plate have projections; and a supporting part correspondingly combined with the bulge part is formed at the top of the inner side wall of the base and used for realizing the sealing and mutual supporting of the front side and the rear side of the base under the state that the cover plate covers the base.

23. The inhaler according to claim 22, wherein the protrusion has a third engaging portion, and the upper edge of the base has a fourth engaging portion corresponding to the third engaging portion.

24. The inhalation device according to claim 1, 22 or 23, wherein the cover plate has fifth engaging portions on both sides thereof, and the base has sixth engaging portions on an upper side edge thereof corresponding to the fifth engaging portions.

25. The inhalation device according to claim 1, wherein the number of said first airflow inlets is two, and said first airflow inlets are respectively located on the front and rear sides of the proximal end of said cover plate.

26. Inhalation device according to claim 25, wherein the area of the first air flow inlet is 3.5 to 15mm each ² 。

27. The inhalation device according to claim 1, wherein said second airflow inlets are two in number and open on either side of the distal end of said cover plate.

28. The inhalation device according to claim 1 or 27, wherein a third air inlet is further opened at a distal side of the base, and the third air inlet communicates with the second air inlet in a state where the cover is fitted to the base.

29. The inhalation device according to claim 1, wherein the second airflow inlet is one in number and opens at the distal end of the cover plate.

30. The inhalation device according to claim 1, wherein the cover plate and capsule magazine are integrally formed.

31. The inhalation device according to claim 1, wherein the chamber of the capsule cartridge comprises a main chamber having a transverse diameter greater than the transverse cross-sectional diameter of the capsule and less than the longitudinal cross-sectional diameter of the capsule.

32. The inhalation device according to claim 31, wherein the ratio of the cross-sectional area of the primary chamber to the sum of the areas of the first and second gas flow inlets is 1:2-1.5.

33. The inhalation device according to claim 31, wherein the chamber bottom of the capsule chamber is provided with a sub-chamber communicating with the main chamber, the bottom end of the sub-chamber is provided with a chamber inlet, and a gap is provided between the chamber inlet and the bottom surface of the base, and the diameter of the sub-chamber is smaller than the transverse cross-sectional diameter of the capsule.

34. The inhalation device according to claim 33 wherein the ratio of the cross-sectional area of the chamber inlet to the sum of the areas of the first and second gas flow inlets is 1:8-1:7.

35. The inhalation device according to claim 1, wherein the chamber of the capsule cartridge comprises a mounting structure for cooperating with the piercing assembly such that the piercing assembly pierces the capsule in the capsule cartridge with its piercing needle during movement relative to the capsule cartridge.

36. The inhalation device according to claim 35, wherein said mounting structure comprises:

the mounting plate is provided with symmetrical clamping grooves;

the abutting part is formed on the mounting plate and is positioned between the symmetrical clamping grooves;

and the two pipe parts are formed on the mounting plate, are respectively positioned on the upper side and the lower side of the abutting part, are communicated with the cavity and are used for limiting the puncturing direction of the puncture needle.

37. The inhalation device according to claim 36, wherein the piercing assembly further comprises a reset mechanism located between the button member and the abutment for being pressed upon movement of the button member in a direction toward the capsule chamber to provide a reset force to return the lancet and the button member to the initial position.

38. The inhalation device according to claim 37, wherein said button member is provided with a mounting block for mounting said reset mechanism.

39. The inhalation device according to claim 36, wherein said lancet is disposed through said tube portion, and a proximal end of said lancet is cooperatively coupled to said button member.

40. The inhalation device according to claim 36, wherein said button member comprises a pressing portion and a movable connecting portion integrally formed with said pressing portion, and a distal end of said movable connecting portion has a stopper portion engaging with said engaging groove.

41. The inhalation device according to claim 40, wherein the distal end of the lancet and the distal end of the movable connecting portion are located on the same vertical line.

42. The inhalation device according to claim 1, wherein the proximal end of the base is provided with an opening to provide a space for the piercing member to move.

43. The inhalation device according to claim 1, wherein the base further comprises a transparent window mounted on the holder body, and the chamber of the capsule chamber has a transparent wall for viewing the state of the capsule in the capsule chamber through the base in the use state.

44. The inhalation device according to claim 43, wherein the transparent windows are located at the distal end of the base and extend to the front and rear sides of the base.

45. The inhalation device according to claim 1, wherein the base has a restrictor plate with air flow guide holes therein for restricting the air flow and controlling the air intake direction.

46. The inhalation device according to claim 45 wherein the restrictor plate is located distally within the base.

47. The inhalation device according to claim 45 or 46 wherein the number of air flow directing apertures is two,symmetrically arranged on the flow limiting plate, and the area of each air flow guide hole is 20-35 mm ² 。

48. An inhalation device according to claim 1 characterised in that the sum of the areas of the first and second air stream inlets is from 50 to 100mm ² 。