CN115414154A - Artificial prosthesis delivery system - Google Patents

Abstract

The invention discloses an artificial prosthesis delivery system, comprising: a housing having a mounting channel; the catheter mechanism comprises a stent catheter component, a positioning catheter component and a bending catheter which are sleeved with each other, the stent is arranged at the far end of the stent catheter component, and the positioning frame is arranged at the far end of the positioning catheter component; the control mechanism comprises a bracket control assembly, a positioning control assembly and a bending adjusting control assembly which are arranged on the shell, and the near end of the bending adjusting catheter is arranged on the installation channel and is connected with the bending adjusting control assembly; the proximal end of the stent catheter assembly and the proximal end of the positioning catheter assembly extend into the mounting channel respectively, the proximal end of the stent catheter assembly is connected to the stent control assembly, and the proximal end of the positioning catheter assembly is connected to the positioning control assembly. The proximal end and the control mechanism of the catheter mechanism are both arranged on the shell, the whole structure is more compact, the shell can provide better protection for the proximal end and the control mechanism of the catheter mechanism, and the convenience in operation can be improved.

Description

Prosthetic delivery system

Technical Field

The present invention relates to the field of valves, and further relates to prosthetic delivery systems.

Background

The heart is divided into left and right parts, each part including a ventricle and an atrium, the ventricle and the atrium and atrium being separated by a ventricular septum and an atrial septum, with valves preventing regurgitation of blood between the atrium, the chamber and the arteries. Wherein, the valve between the left atrium and the left ventricle is a mitral valve, the valve between the right atrium and the right ventricle is a tricuspid valve, the valve between the left ventricle and the aorta is an aortic valve, and the valve between the right ventricle and the pulmonary artery is a pulmonary valve.

The aforementioned valves open and close in response to the contraction and relaxation of the heart, and therefore the valves of the heart must withstand prolonged flushing with blood and squeezing of the blood and surrounding annulus. When the valve fails to close completely and open insufficiently, which results in insufficient blood supply and regurgitation, physicians sometimes recommend placement of a heart valve stent by minimally invasive intervention in order to improve the blood supply and regurgitation.

The valve stent is implanted into a preset position in a patient body through a catheter by a conveying appliance in the prior art, and the valve stent is usually matched with a movable stent to be used together in the implantation process, so that the valve stent not only can occupy larger space, but also has a complex structure and is complex to operate. On the other hand, in the process of implanting the valve stent by using the existing transporter, the angle adjustment of the valve stent is difficult, so that the implantation precision of the valve stent is low.

Disclosure of Invention

In view of the above technical problems, an object of the present invention is to provide a transcatheter conveying device, in which the proximal end of the catheter mechanism and the control mechanism are both mounted on the housing, so that the overall structure is more compact, the housing can provide better protection for the proximal end of the catheter mechanism and the control mechanism, and the convenience of operation can be improved.

In order to achieve the above object, the present invention provides a delivery system for an artificial prosthesis including a stent and a positioning frame, the delivery system comprising:

a housing having a mounting channel;

the catheter mechanism comprises a stent catheter component, a positioning catheter component and a bending catheter which are sleeved with each other, the stent is arranged at the distal end of the stent catheter component, and the positioning frame is arranged at the distal end of the positioning catheter component;

the control mechanism comprises a bracket control assembly, a positioning control assembly and a bending adjusting control assembly which are arranged on the shell, the near end of the bending adjusting catheter is arranged on the installation channel and is connected with the bending adjusting control assembly, and the bending adjusting control assembly is used for controlling bending adjustment of the bending adjusting catheter and release of the positioning frame; the proximal end of the stent catheter assembly and the proximal end of the positioning catheter assembly respectively extend into the mounting channel, the proximal end of the stent catheter assembly is connected to the stent control assembly, the proximal end of the positioning catheter assembly is connected to the positioning control assembly, the stent control assembly is used for controlling the distal action of the stent catheter assembly to control the positioning and releasing of the stent, and the positioning control assembly is used for controlling the distal action of the positioning catheter assembly to control the positioning and releasing of the positioning frame.

In the above artificial prosthesis delivery system, the housing includes a bending adjustment housing and an implantation housing, a distal end of the implantation housing is rotatably mounted to a proximal end of the bending adjustment housing, a proximal end of the bending adjustment catheter extends to the bending adjustment housing, proximal ends of the stent catheter assembly and the positioning catheter assembly extend to the implantation housing, and rotating the implantation housing relative to the bending adjustment housing can drive the distal ends of the stent catheter assembly and the positioning catheter assembly to rotate so as to adjust an angle of the stent and the positioning frame.

The artificial prosthesis delivery system further comprises a rotation limiting member installed at a joint of the bending adjustment housing and the implantation housing, wherein the rotation limiting member has a rotation state and a limiting state, and in the rotation state, the implantation housing can rotate relative to the bending adjustment housing; in the limiting state, the rotation limiting part can limit the implant shell and the bending adjusting shell.

In the above artificial prosthesis delivery system, the rotation limiting member includes a first limiting member, a second limiting member and an operating member, the first limiting member is fixed to the proximal end of the bending adjustment housing, and the second limiting member is movably mounted to the implantation housing; in the limiting state, the second limiting part abuts against the first limiting part; in the rotating state, the first limiting piece and the second limiting piece are separated; the operating part is connected in the second locating part, the operating part can drive the second locating part to move, so that the rotating locating part is controlled to be switched between the rotating state and the limiting state.

In the above artificial prosthesis delivery system, the first limiting member is a latch fixed to the bending adjustment housing, the second limiting member is a latch fixed to the operating member, the implantation housing has a movable opening, and one end of the operating member, which is away from the second limiting member, extends out of the movable opening; the rotation limiting part further comprises an elastic part, and the elastic part abuts against the operating part; in the limiting state, the clamping block is clamped in the clamping tooth, and the elastic piece is in an initial state; pressing the operating piece to compress the elastic piece, separating the clamping block from the clamping tooth, and switching the rotation limiting piece to the rotation state; and when the operating piece is loosened, the elastic piece can push the clamping block to return.

In the above artificial prosthesis delivery system, the number of the operation members, the number of the second limit members, and the number of the elastic members of the rotation limit members are two, the two operation members and the two second limit members are symmetrically installed on the implantation housing, two ends of the two elastic members are respectively abutted against the two operation members, and an avoidance space through which the stent catheter assembly and the positioning catheter assembly pass is formed between the two elastic members arranged at intervals.

In the above artificial prosthesis delivery system, the rotation limiting member includes a first self-locking thread fixed to the bend-adjusting housing and a second self-locking thread fixed to the implant housing, and the first self-locking thread is in thread fit with the second self-locking thread.

In the above prosthesis delivery system, the bending shell comprises a first shell and a second shell, the mounting channel corresponding to the first shell is a first channel, the mounting channel corresponding to the second shell is a second channel, and the proximal end of the first shell is telescopically mounted in the second channel;

the first housing has a first rotating portion having a first slide hole communicating with the first passage, the second housing has a second rotating portion having a second slide hole communicating with the second passage;

the bending adjusting control assembly comprises a first knob, a second knob and a first traction piece, the first traction piece is movably arranged in the first channel, and a second traction piece is fixed at the near end of the first shell;

the end parts of the first traction piece and the second traction piece respectively extend out of the first sliding hole and the second sliding hole, the first knob is rotatably sleeved on the first rotating part and connected to the end part of the first traction piece, the second knob is rotatably sleeved on the second rotating part and connected to the end part of the second traction piece, the first knob can be rotated to drive the first traction piece to axially move, and the second knob can be rotated to drive the first shell to axially move; the proximal end of the bending adjusting catheter is fixed to the first shell, and the proximal end of the bending adjusting pull wire of the bending adjusting catheter is fixed to the first traction piece.

In the prosthesis delivery system, the first traction element includes a traction body having a traction channel, and a traction tooth mounted on the traction body, and the bending catheter is slidably mounted on the traction channel.

In the above prosthesis delivery system, the sidewall of the traction channel further has an axially extending limiting groove communicating with the traction channel, and the proximal end of the bending catheter has an outwardly protruding and axially extending limiting projection slidably mounted in the limiting groove.

In the above artificial prosthesis delivery system, the implantation housing includes a third housing, the installation channel corresponding to the third housing is a third channel, the third housing includes a rotation connection section, a second catheter fixing section, a third rotation portion and a third catheter fixing section in sequence from a distal end to a proximal end, and the rotation connection section is rotatably connected to the bending adjustment housing;

the positioning catheter component comprises a second catheter and a third catheter which are sleeved with each other;

the positioning control assembly comprises a second fixing piece, a third traction piece, a third knob and a third fixing piece, the second fixing piece is fixed in the third channel corresponding to the second catheter fixing section, and the near end of the second catheter is fixed on the second fixing piece; the third traction piece and the third fixing piece are arranged in the third channel corresponding to the third rotating part, the proximal end of the third catheter is fixedly connected to the third fixing piece, and the third traction piece is fixed to the third fixing piece;

the third rotating portion is provided with a third sliding hole which is communicated with the third channel and axially extends, the end of the third traction piece extends out of the third sliding hole, the third knob is rotatably sleeved on the third rotating portion, the third knob is connected to the end of the third traction piece, and the third traction piece can be driven to drive the third guide pipe to axially move by rotating the third knob.

In the above prosthesis delivery system, the proximal end of the third housing further comprises a fourth rotating part, and the installation channel corresponding to the fourth rotating part is a fourth channel;

the implantation shell further comprises a fourth shell, the fourth shell sequentially comprises a telescopic connecting part and a fifth rotating part from a far end to a near end, the telescopic connecting part is telescopically installed in the fourth channel, the installation channel corresponding to the telescopic connecting part is a fifth channel, and the installation channel corresponding to the fifth rotating part is a sixth channel;

the bracket control assembly comprises a fourth traction piece, a fifth traction piece, a fourth fixing piece, a fifth fixing piece, a fourth knob and a fifth knob, the fourth knob is rotatably sleeved on the fourth rotating part, the fifth knob is rotatably sleeved on the fifth rotating part, the fourth traction piece is fixed at the far end of the telescopic connecting part, the fourth fixing piece is fixed on the fifth channel, the fifth traction piece and the fifth fixing piece are movably arranged on the sixth channel, and the fifth traction piece is connected to the fifth fixing piece;

the stent catheter assembly comprises a fourth catheter and a fifth catheter which are sleeved with each other, the proximal end of the fourth catheter is fixed on the fourth fixing piece, and the proximal end of the fifth catheter is fixed on the fifth fixing piece;

the fourth rotating part is provided with a fourth sliding hole communicated with the fourth channel, the end of the fourth traction piece extends out of the fourth sliding hole, the fourth knob is rotatably sleeved on the fourth rotating part and is connected to the end of the fourth traction piece, and the fourth knob can be rotated to drive the fourth traction piece, the fourth fixing piece, the fourth shell and the stent catheter assembly to synchronously and axially move;

the fifth rotating part is provided with a fifth sliding hole communicated with the sixth channel, the end part of the fifth traction piece extends out of the fifth sliding hole, the fifth knob is rotatably sleeved on the fifth rotating part and connected to the end part of the fifth traction piece, and the fifth knob can be rotated to drive the fifth traction piece, the fifth fixing piece and the fifth guide pipe to move axially.

In the above artificial prosthesis delivery system, the artificial prosthesis delivery system further comprises a positioning release assembly mounted at the distal end of the positioning catheter assembly, the positioning release assembly comprises a clamping arm and a control arm, the proximal end of the clamping arm is fixed at the distal end of the second catheter, the distal end of the clamping arm is provided with a clamping jaw, and the clamping jaw is suitable for clamping the proximal end of the positioning frame;

the proximal end of the control arm is fixed at the distal end of the third catheter, and the distal end of the control arm is provided with a control sleeve;

the clamping arm is slidably mounted on the control sleeve, and the control sleeve can be moved relative to the clamping arm to control the clamping jaws to be switched between a first clamping state and a first releasing state, wherein the clamping jaws loosen the positioning frame in the first releasing state, and the clamping jaws clamp the positioning frame in the first clamping state.

In the above artificial prosthesis delivery system, the artificial prosthesis delivery system further comprises a stent release assembly mounted at the distal end of the stent catheter assembly, the stent release assembly comprises a distal sleeve and a bayonet joint, the bayonet joint is fixed at the distal end of the fourth catheter, and the distal end of the fifth catheter extends into the distal sleeve and is fixedly connected to the distal end of the distal sleeve;

the clamping groove is formed in the periphery of the clamping joint and used for accommodating the buckle at the far end of the bracket, and the clamping joint is telescopically arranged on the far-end sleeve;

the support release assembly is provided with a second clamping state and a second release state, in the second clamping state, the clamping joint is located in the far-end sleeve, the buckle at the far end of the support is located in the clamping groove, and the far-end sleeve covers the opening of the clamping groove to limit the buckle;

in the second release state, the clamping groove of the clamping connector moves to the outer side of the far-end sleeve, and the support expands to enable the buckle to be separated from the clamping groove.

Compared with the prior art, the artificial prosthesis delivery system provided by the application has at least one of the following beneficial effects:

1. according to the artificial prosthesis conveying system, the near end of the catheter mechanism and the control mechanism are both arranged on the shell, the overall structure is more compact, the shell can provide better protection for the near end of the catheter mechanism and the control mechanism, and the operation convenience can be improved;

2. according to the artificial prosthesis delivery system, the implanting shell can rotate relative to the bending shell, the angle between the positioning frame and the support can be adjusted according to needs under the condition that the bending catheter is kept not to rotate in the implanting process, so that the positioning frame and the support can be implanted into a preset position at a better angle, and the implanting precision of the positioning frame and the support can be improved;

3. the application provides an artificial prosthesis conveying system, before the joint groove motion of joint head to the telescopic outside of distal end, the support with the recoverable release again of locating rack increases the repeated location ability, improves security in the art, convenient to popularize and apply.

Drawings

The above features, technical features, advantages and modes of realisation of the present invention will be further described in the following detailed description of preferred embodiments thereof, which is to be read in connection with the accompanying drawings.

FIGS. 1 and 2 are schematic perspective views of a prosthetic delivery system according to a preferred embodiment of the present invention;

FIGS. 3 and 4 are schematic exploded views of a prosthetic delivery system according to a preferred embodiment of the present invention;

FIG. 5 is a schematic top view of a prosthetic delivery system according to a preferred embodiment of the present invention;

FIG. 6 isbase:Sub>A cross-sectional view taken along line A-A of FIG. 5;

FIG. 7 is an exploded view of the bend adjustment housing of the prosthetic delivery system of the preferred embodiment of the present invention;

FIG. 8 is a schematic perspective view of a first housing of the prosthetic delivery system of the preferred embodiment of the present invention;

FIG. 9 is a perspective view of a second housing of the prosthetic delivery system of the preferred embodiment of the present invention;

FIG. 10 is an enlarged schematic view of a portion a of FIG. 4;

FIG. 11 is a cross-sectional view taken along line B-B of FIG. 10;

FIG. 12 is an enlarged schematic view of the structure of FIG. 6 at d;

FIG. 13 is an exploded view of a third housing of the prosthetic delivery system of the preferred embodiment of the present invention;

FIG. 14 is a perspective view of a third housing of the prosthetic delivery system of the preferred embodiment of the present invention;

FIG. 15 is an enlarged schematic view of the structure at b in FIG. 4;

FIG. 16 is an enlarged schematic view of FIG. 6 at e;

FIG. 17 is an exploded view of a fourth housing of the prosthetic delivery system of the preferred embodiment of the present invention;

FIG. 18 is a schematic perspective view of a fourth housing of the prosthetic delivery system of the preferred embodiment of the present invention;

FIG. 19 is an enlarged schematic view of the structure of FIG. 4 at c;

FIG. 20 is an enlarged schematic view of the structure of FIG. 6 at f;

FIGS. 21 and 22 are schematic distal end configurations of the catheter mechanism of the prosthetic delivery system of the preferred embodiment of the present invention;

FIG. 23 is an enlarged schematic view of FIG. 22 at g;

FIG. 24 is an enlarged schematic view of the structure at h in FIG. 22;

FIG. 25 is a schematic illustration of the construction of a prosthesis of the prosthesis delivery system of the preferred embodiment of the present invention;

FIG. 26 is a schematic illustration of a prosthesis implantation procedure for the prosthesis delivery system of the preferred embodiment of the present invention.

The reference numbers illustrate:

a housing 10, an installation channel 11, a bending adjusting housing 12, a first housing 121, a first conduit fixing section 1211, a second housing 122, a rotation connecting groove 1220, an implant housing 13, a third housing 131, a rotation connecting section 1311, a second conduit fixing section 1312, a third rotation part 1313, a third rotation groove 1310, a third conduit fixing section 1314, a fourth rotation part 1315, a movable opening 1316, a fourth housing 132, a telescopic connecting part 1321, a fifth rotation part 1322, a fourth conduit fixing section 1323, a rotation limiting member 14, a first limiting member 141, a second limiting member 142, an operation member 143, an elastic member 144, a first rotation part 151, a first rotation groove 1510, a second rotation part 152, a second rotation groove 1520, a conduit mechanism 20, a stent conduit assembly 21, a fourth conduit 211, a fifth conduit 212, a positioning conduit assembly 22, a second conduit 221, a third conduit 222, a bending adjusting conduit 23, a limiting protrusion 231, and a control mechanism 30, a bracket control assembly 31, a fourth pulling member 311, a fifth pulling member 312, a fourth fixing member 313, a fifth fixing member 314, a fourth knob 315, a fifth knob 316, a fourth evacuation tube 3171, a fourth sealing ring 3172, a fourth fixing bolt 3173, a rear end cap 3181, a fifth evacuation tube 3182, a positioning control assembly 32, a second fixing member 321, a third pulling member 322, a third knob 323, a third fixing member 324, a second evacuation tube 3241, a second sealing ring 3242, a second fixing bolt 3243, a third evacuation tube 3251, a third sealing ring 3252, a third fixing bolt 3253, a bending control assembly 33, a first knob 331, a second knob 332, a first pulling member 333, a pulling body 3331, a pulling tooth 3332, a pulling channel 3330, a limiting groove 3333, a limiting convex plate 3334, a fixing hole 3335, a fixing member 3336, a second pulling member 334, a first fixing member 335, a first evacuation tube 336, a first sealing ring 337, and a first sealing ring 338, positioning release assembly 40, clamping arm 41, clamping jaw 411, control arm 42, control sleeve 421, stent release assembly 50, distal sleeve 51, clamping head 52, clamping groove 521, first section groove 5211, second section groove 5212, artificial prosthesis 200, positioning frame 201, stent 202 and connecting rod 203.

Detailed Description

In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the following description will be made with reference to the accompanying drawings. It is obvious that the drawings in the following description are only some examples of the invention, and that for a person skilled in the art, other drawings and embodiments can be derived from them without inventive effort.

For the sake of simplicity, only the parts relevant to the invention are schematically shown in the drawings, and they do not represent the actual structure as a product. Moreover, in the interest of brevity and understanding, only one of the components having the same structure or function is illustrated schematically or designated in some of the drawings. In this document, "one" means not only "only one" but also a case of "more than one".

It should be further understood that the term "and/or" as used in this specification and the appended claims refers to and includes any and all possible combinations of one or more of the associated listed items.

In this context, it is to be understood that, unless otherwise explicitly stated or limited, the terms "mounted," "connected," and "connected" are to be construed broadly, e.g., as meaning either a fixed connection, a removable connection, or an integral connection; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meanings of the above terms in the present invention can be understood in specific cases to those skilled in the art.

In addition, in the description of the present application, the terms "first", "second", and the like are used only for distinguishing the description, and are not intended to indicate or imply relative importance.

In this application, "proximal" and "distal" are relative orientations, relative positions, directions of elements or actions with respect to each other from the perspective of a clinician using the medical device, although "proximal" and "distal" are not intended to be limiting, with "proximal" generally referring to the end of the medical device that is closer to the clinician during normal operation and "distal" generally referring to the end that is first introduced into a patient.

Referring to fig. 1-26, the present invention provides a prosthesis delivery system adapted to implant a prosthesis 200 at a predetermined location in a patient, the prosthesis 200 including a spacer 201 and a stent 202. The artificial prosthesis delivery system comprises a shell 10, a catheter mechanism 20 and a control mechanism 30, wherein the shell 10 is provided with a mounting channel 11; the catheter mechanism 20 comprises a stent catheter component 21, a positioning catheter component 22 and a bending catheter 23 which are sleeved with each other, the stent 202 is installed at the distal end of the stent catheter component 21, and the positioning frame 201 is installed at the distal end of the positioning catheter component 22; the control mechanism 30 comprises a bracket control assembly 31, a positioning control assembly 32 and a bending control assembly 33 which are mounted on the housing 10, the proximal end of the bending adjusting catheter 23 is mounted on the mounting channel 11 and connected to the bending adjusting control assembly 33, and the bending adjusting control assembly 33 is used for controlling bending adjustment of the bending adjusting catheter 23 and release of the positioning frame 201; the proximal end of the stent catheter assembly 21 and the proximal end of the positioning catheter assembly 22 extend into the installation channel 11 respectively, the proximal end of the stent catheter assembly 21 is connected to the stent control assembly 31, the proximal end of the positioning catheter assembly 22 is connected to the positioning control assembly 32, the stent control assembly 31 is used for controlling the distal action of the stent catheter assembly 21 to control the positioning and releasing of the stent 202, and the positioning control assembly 32 is used for controlling the distal action of the positioning catheter assembly 22 to control the positioning and releasing of the positioning frame 201.

In the artificial prosthesis delivery system provided by the invention, the proximal end of the catheter mechanism 20 and the control mechanism 30 are both mounted on the housing 10, so that the overall structure is more compact, the housing can provide better protection for the proximal end of the catheter mechanism 20 and the control mechanism 30, and the convenience in operation can be improved.

Specifically, the housing 10 includes a bending housing 12 and an implantation housing 13. The distal end of the implantation shell 13 is rotatably mounted on the proximal end of the bending shell 12, the proximal end of the bending catheter 23 extends to the bending shell 12, the proximal ends of the stent catheter assembly 21 and the positioning catheter assembly 22 extend to the implantation shell 13, and rotating the implantation shell 13 relative to the bending shell 12 can drive the distal ends of the stent catheter assembly 21 and the positioning catheter assembly 22 to rotate so as to adjust the angles of the stent 202 and the positioning frame 201.

The implantation housing 13 is rotatable relative to the bending adjustment housing 12, and the angles of the positioning frame 201 and the stent 202 can be adjusted as required under the condition that the bending adjustment catheter 23 is not rotated in the implantation process, so that the positioning frame 201 and the stent 202 can be implanted into a preset position at a better angle, and the implantation accuracy of the positioning frame 201 and the stent 202 can be improved.

Specifically, the prosthesis delivery system further comprises a rotation limiting member 14 installed at the connection between the bending adjustment housing 12 and the implantation housing 13. The rotation limiting member 14 has a rotation state in which the implant housing 13 can rotate relative to the bending adjustment housing 12 and a limiting state; in the limiting state, the rotation limiting member 14 can limit the implant shell 13 and the bending adjustment shell 12, so as to limit the implant shell 13 from rotating relative to the bending adjustment shell 12.

Referring to fig. 13 and 15, in some embodiments, the rotation limiting member 14 includes a first limiting member 141, a second limiting member 142, and an operating member 143. The first limiting member 141 is fixed to the proximal end of the bending adjustment housing 12, and the second limiting member 142 is movably mounted to the implantation housing 13; in the limiting state, the second limiting member 142 abuts against the first limiting member 141 to limit the rotation of the implanted shell 13 relative to the bending adjustment shell 12; in the rotation state, the first limiting member 141 and the second limiting member 142 are separated, and the implant housing 13 can rotate relative to the bending adjustment housing 12; the operating element 143 is connected to the second limiting element 142, and the operating element 143 can drive the second limiting element 142 to move relative to the first limiting element 141, so as to control the rotation limiting element 14 to switch between the rotation state and the limiting state.

Specifically, the first limiting member 141 is a latch fixed to the bending adjustment housing 12, the second limiting member 142 is a latch fixed to the operating member 143, the implant housing 13 has a movable opening 1316, and an end of the operating member 143 away from the second limiting member 142 extends out of the movable opening 1316; the rotation limiting member 14 further includes an elastic member 144, the elastic member 144 abuts against the operating member 143, a side wall of the movable opening 1316 further has a limiting hole, and the latching block extends out of the limiting hole; in the limit state, the fixture block is clamped to the latch, and the elastic member 144 is in an initial state; pressing the operating element 143 compresses the elastic element 144, the latch is separated from the latch, and the rotation limiting element 14 is switched to the rotating state; when the operating element 143 is released, the elastic element 144 can push the latch to return to and abut against the latch. That is, pressing the operation element 143 or driving the second limiting element 142 by the elastic element 144 to move along the radial direction of the housing 10 controls the rotation limiting element 14 to switch between the rotation state and the limiting state. In a modified embodiment, the operating element 143 can slide along the axial direction of the housing 10, and pushing the operating element 143 to slide axially relative to the housing 10 can drive the second limiting element 142 to move axially, so that the second limiting element 142 is separated from the first limiting element 141, and the rotation limiting element 14 is switched to the rotation state; after the operating element 143 is released, the elastic element 144 can push the operating element 143 to move axially, so that the rotation limiting element 14 is switched to the limiting state.

Referring to fig. 13 and 15, preferably, the number of the operation members 143, the second limiting members 142, and the elastic members 144 of the rotation limiting member 14 is two, the two operation members 143 and the two second limiting members 142 are symmetrically mounted on the implantation housing 13, two ends of the two elastic members 144 abut against the two operation members 143, and an avoidance space for the stent catheter assembly 21 and the positioning catheter assembly 22 to pass through is formed between the two elastic members 144 arranged at intervals. The operating member 143 has a groove at an end connected to the elastic member 144 for receiving an end of the elastic member 144 to prevent the end of the elastic member 144 from sliding with respect to the operating member 143. Preferably, the elastic member is a spring.

In a modified embodiment, the rotation limiting member 14 includes a first self-locking thread fixed at the proximal end of the bending adjustment housing 12 and a second self-locking thread fixed at the distal end of the implantation housing 13, and the first self-locking thread and the second self-locking thread are in threaded engagement. The first self-locking thread and the second self-locking thread can realize a self-locking function, and when the implantation shell 13 is rotated by using external force, the first self-locking thread can rotate relative to the second self-locking thread; after the external force acting on the implanted shell 13 disappears, the first self-locking thread and the second self-locking thread can realize self-locking matching, so that the resistance of the implanted shell 13 relative to the rotation of the bending adjusting shell 12 is improved, and the implanted shell 13 is limited to rotate relative to the bending adjusting shell 12.

Referring to fig. 3, 4, 7, 8, 9 and 12, the bend adjusting housing 12 includes a first housing 121 and a second housing 122. The portion of the mounting channel 11 corresponding to the first housing 121 is a first channel, the portion of the mounting channel 11 corresponding to the second housing 122 is a second channel, and the proximal end of the first housing 121 is telescopically mounted in the second channel.

The first housing 121 has a first rotating portion 151, and the second housing 122 has a second rotating portion 152. The first rotating portion 151 has a first sliding hole communicating with the first passage, and the second rotating portion 152 has a second sliding hole communicating with the second passage, the first sliding hole and the second sliding hole extending in the axial direction of the bend adjusting housing 12, respectively.

The bend adjustment control assembly 33 includes a first knob 331, a second knob 332, a first pulling member 333, and a second pulling member 334. The first pulling member 333 is movably mounted to the first channel, and the second pulling member 334 is fixed to the proximal end of the first housing 121.

The end portions of the first pulling member 333 and the second pulling member 334 respectively extend out of the first sliding hole and the second sliding hole, the first knob 331 is rotatably sleeved on the first rotating portion 151 and connected to the end portion of the first pulling member 333, the second knob 332 is rotatably sleeved on the second rotating portion 152 and connected to the end portion of the second pulling member 334, the first knob 331 can be rotated to drive the first pulling member 333 to move axially, and the second knob 332 can be rotated to drive the first housing 121 to move axially; the proximal end of the bending catheter 23 is fixed to the first housing 121, and the proximal end of the bending pull wire of the bending catheter 23 is fixed to the first traction member 333.

In use, rotating the first knob 331 relative to the first housing 121 can drive the first pulling element 333 to axially move in the first channel of the first housing 121, so as to drive the proximal end of the bending adjustment pulling wire of the bending adjustment catheter 23 to axially move, and the distal end of the bending adjustment pulling wire is connected to the distal end of the bending adjustment catheter 23, so as to control the distal bending of the bending adjustment catheter 23. The second knob 332 is rotated to drive the first housing 121 to integrally move axially, and the proximal end of the bending adjustment catheter 23 is fixed to the first housing 121, so that the bending adjustment catheter 23 can be driven to move axially.

Further, the first rotating portion 151 of the first housing 121 has a first rotating groove 1510, and the first knob 331 is rotatably mounted to the first rotating groove 1510. Both ends of the first knob 331 abut on both end inner walls of the first rotation groove 1510, and when the first knob 331 is rotated with respect to the first housing 121, the first knob 331 can rotate with respect to the first housing 121 but does not axially move with respect to the first housing 121. The inner wall of the first knob 331 is provided with an internal thread, the end of the first pulling member 333 is provided with a meshing tooth, the meshing tooth is in threaded fit with the internal thread, and the first pulling member 333 can be pushed to move axially when the first knob 331 is rotated. In a modified embodiment, an inner wall of the first knob 331 is screwed to an outer wall of the first rotating portion 151, the inner wall of the first knob 331 has a pushing groove circumferentially provided, an end of the first pulling member 333 is rotatably mounted to the pushing groove, and when the first knob 331 is rotated with respect to the first housing 121, the first knob 331 is rotated while being axially moved, and the first pulling member 333 is pushed while being axially moved.

The second rotating portion 152 of the second housing 122 has a second rotating groove 1520, and the second knob 332 is rotatably mounted to the second rotating groove 1520. The connection manner of the second knob 332 and the second pulling member 334 is similar to that of the first knob 331 and the first pulling member 333, and is not described herein again.

Referring to fig. 10 and 11, the first pulling member 333 includes a pulling body 3331 and pulling teeth 3332 mounted to the pulling body. The distraction body 3331 has a distraction channel 3330 and the bend tuning catheter 23 is slidably mounted to the distraction channel 3330. Preferably, the traction teeth 3332 are integrally coupled with the traction body 3331. Preferably, the number of the drawing teeth 3332 of the first drawing member 333 is two or more, and the number of the first sliding holes on the first rotating part 151 is the same as the number of the drawing teeth 332, so that the first drawing member 333 can be contacted with the first knob 331 at multiple positions, and the force applied to the first drawing member 333 is more uniform, and the operation is more stable.

The sidewall of the drawing channel 3330 further has a limiting groove 3333 communicating with the drawing channel 3330 and extending axially, the proximal end of the bend adjustment guiding tube 23 has a limiting protrusion 231 protruding outwards and extending axially, and the limiting protrusion 231 is slidably mounted in the limiting groove 3333. The first drawing member 333 can be loaded in a predetermined direction by the mutual engagement between the limiting groove 3333 and the limiting protrusion 231. On the other hand, the first pulling member 333 can be limited in the circumferential direction by the mutual engagement between the limiting groove 3333 and the limiting protrusion 231, and the first pulling member 333 is further prevented from rotating relative to the bending adjustment guide tube 23.

Further, the first traction member 333 further includes a limit protruding plate 3334 disposed on the traction body 3331, a limit groove is disposed in the first housing 121, the limit protruding plate 3334 is slidably mounted in the limit groove, and the first traction member 333 is limited by the cooperation between the limit protruding plate 3334 and the limit groove, so as to prevent the first traction member 333 from radially displacing.

The traction main body 3331 is further provided with a fixing hole 3335, the first traction member 333 further includes a fixing member 3336 fixed to the traction main body 3331, and the proximal end of the bending adjustment pull wire of the bending adjustment catheter 23 passes through the fixing hole 3335 and then is fixedly connected to the fixing member 3336.

Referring to fig. 8 and 10, the first housing 121 further has a first catheter fixing section 1211. The curve-adjusting control assembly 33 further comprises a first fastener 335, the first fastener 335 is fixed in the first catheter tube fixing section 1211, and the proximal end of the curve-adjusting catheter 23 is fixed in the first fastener 335. Preferably, the limiting protrusion 231 is disposed on the first fixing element 335, and a portion of the distal end of the first fixing element 335 connected to the bend adjustment guiding tube 23 is slidably mounted on the drawing channel 3330.

The bend adjustment control assembly 33 further includes a first drain pipe 336, a first sealing ring 337, and a first securing pin 338. The first exhaust pipe 336 is installed to the first pipe fixing section 1211 for exhausting gas in the gap between the turning pipe 23 and the second pipe 221 in the positioning pipe assembly 22. The first sealing ring 337 and the first fixing bolt 338 are respectively sleeved on the positioning guide assembly 22, and the first fixing bolt 338 is threadedly connected to the first fixing member 335 and compresses the first sealing ring 337 to prevent liquid leakage.

Referring to fig. 3, 4, 12, 13 and 14, the implant housing 13 includes a third housing 131, a portion of the third housing 131 corresponding to the installation channel 11 is a third channel, the third housing 131 includes a rotation connection section 1311, a second catheter fixing section 1312, a third rotation portion 1313 and a third catheter fixing section 1314 sequentially from a distal end to a proximal end, and the rotation connection section 1311 is rotatably connected to the bending adjustment housing 12. The proximal end of the second casing 122 has a rotation coupling groove 1220, and the rotation coupling section 1311 of the third casing 131 is rotatably mounted to the rotation coupling groove 1220 and can restrain the third casing 131 in an axial direction.

The positioning catheter assembly 22 includes a second catheter 221 and a third catheter 222 nested with each other. The positioning control assembly 32 includes a second fixing member 321, a third pulling member 322, a third knob 323, and a third fixing member 324. The second fixing element 321 is fixed in the third channel corresponding to the second catheter fixing segment 1312, and the proximal end of the second catheter 221 is fixed to the second fixing element 321; the third pulling member 322 and the third fixing member 324 are installed in the third channel corresponding to the third rotating part 1313, and the proximal end of the third catheter 222 is fixedly connected to the third fixing member 324, and the third pulling member 322 is fixed to the third fixing member 324.

The third rotating portion 1313 has a third sliding hole communicated with the third channel and extending axially, an end of the third pulling member 322 extends out of the third sliding hole, the third knob 323 is rotatably sleeved on the third rotating portion 1313, the third knob 323 is connected to the end of the third pulling member 322, and the third knob 323 can be rotated to drive the third pulling member 322 to drive the third guiding pipe 222 to move axially.

The positioning control assembly 32 further includes a second evacuated tube 3241, a second sealing ring 3242, and a second securing pin 3243. The second exhaust pipe 3241 is installed at the second guide pipe fixing section 1312 to exhaust gas between the second guide pipe 221 and the third guide pipe 222. The second sealing ring 3242 and the second fixing bolt 3243 are sleeved outside the third guide tube 222, and the second fixing bolt 3243 is screwed to the proximal end of the second fixing element 321 and presses the second sealing ring 3242.

The positioning control assembly 32 further includes a third evacuated tube 3251, a third sealing ring 3252, and a third securing pin 3253. The third exhaust pipe 3251 is installed at the third catheter fixing section 1314, and is used for discharging the liquid between the third catheter 222 and the stent catheter assembly 21. The third sealing ring 3252 and the third fixing bolt 3253 are sleeved outside the stent catheter assembly 21, and the third fixing bolt 3253 is screwed to the proximal end of the third fixing member 324 and presses the third sealing ring 3252.

Accordingly, the third rotating portion 1313 of the third housing 131 has a third rotating groove 1310, the third knob 323 is rotatably mounted to the third rotating groove 1310, and both ends of the third knob 323 abut against the inner wall of the third rotating groove 1310. The specific connection manner of the third knob 323 and the third pulling member 322 is the same as that of the first knob 331 and the first pulling member 333, and is not described herein again.

Referring to fig. 14, further, the proximal end of the third casing 131 further includes a fourth rotating portion 1315, and a portion of the mounting channel 11 corresponding to the fourth rotating portion 1315 is a fourth channel.

Referring to fig. 3, 4 and 18, the implant housing 13 further includes a fourth housing 132. The fourth housing 132 includes a telescopic connection portion 1321 and a fifth rotation portion 1322 from the distal end to the proximal end. The telescopic connection portion 1321 is telescopically installed in the fourth channel, a portion of the installation channel 11 corresponding to the telescopic connection portion 1321 is a fifth channel, and a portion of the installation channel 11 corresponding to the fifth rotation portion 1322 is a sixth channel.

Referring to fig. 17 and 19, the stand control assembly 31 includes a fourth pulling member 311, a fifth pulling member 312, a fourth fixing member 313, a fifth fixing member 314, a fourth knob 315, and a fifth knob 316. The fourth knob 315 is rotatably sleeved on the fourth rotating portion 1315, the fifth knob 316 is rotatably sleeved on the fifth rotating portion 1322, the fourth pulling element 311 is fixed to the distal end of the telescopic connecting portion 1321, the fourth fixing element 313 is fixed to the fifth channel, the fifth pulling element 312 and the fifth fixing element 314 are movably installed on the sixth channel, and the fifth pulling element 312 is connected to the fifth fixing element 314.

Referring to fig. 20, the stent catheter assembly 21 includes a fourth catheter 211 and a fifth catheter 212 nested with each other. The proximal end of the fourth catheter tube 211 is fixed to the fourth fixing member 313, and the proximal end of the fifth catheter tube 212 is fixed to the fifth fixing member 314.

Referring to fig. 14 and 18, the fourth rotating portion 1315 has a fourth sliding hole communicated with the fourth channel, an end of the fourth pulling member 311 extends out of the fourth sliding hole, the fourth knob 315 is rotatably sleeved on the fourth rotating portion 1315 and connected to an end of the fourth pulling member 311, and rotating the fourth knob 315 can drive the fourth pulling member 311, the fourth fixing member 313, the fourth housing 132 and the stent catheter assembly 21 to synchronously move axially.

The fifth rotating portion 1322 has a fifth sliding hole communicated with the sixth channel, an end of the fifth pulling member 312 extends out of the fifth sliding hole, the fifth knob 316 is rotatably sleeved on the fifth rotating portion 1322 and is connected to the end of the fifth pulling member 312, and rotating the fifth knob 316 can drive the fifth pulling member 312, the fifth fixing member 314 and the fifth conduit 212 to move axially.

The fourth rotating part 1315 has a fourth rotating groove, the fifth rotating part 1322 has a fifth rotating groove, and the fourth knob 315 is rotatably mounted to the fourth rotating groove and abuts against an inner wall of the fourth rotating groove; the fifth knob 316 is rotatably mounted to the fifth rotation groove and abuts against an inner wall of the fifth rotation groove. The connection manner of the fourth knob 315 and the fourth pulling member 311, the connection manner of the fifth knob 316 and the fifth pulling member 312, and the connection manner of the first knob 331 and the first pulling member 333 are not described herein again.

Further, referring to fig. 18, 19 and 20, the fourth shell 132 further includes a fourth conduit fixing segment 1323. The fourth fixing member 313 is fixed to the fourth catheter fixing segment 1323. The rack control assembly 31 further includes a fourth evacuation tube 3171, a fourth sealing ring 3172, and a fourth securing latch 3173. The fourth evacuation pipe 3171 is installed at the fourth guide pipe fixing section 1323 and connected to the fourth fixing member 313, for exhausting gas between the fourth guide pipe 211 and the fifth guide pipe 212. The fourth fixing bolt 3173 and the fourth sealing ring 3172 are respectively sleeved on the fifth guide tube 212, and the fourth fixing bolt 3173 is screwed on the proximal end of the fourth fixing member 313 and presses the fourth sealing ring 3172.

The rack control assembly 31 further includes a rear end cap 3181 and a fifth evacuation tube 3182. The rear end cap 3181 is mounted to the proximal end of the fourth housing 132, and the fifth evacuation pipe 3182 is mounted to the proximal end of the fifth conduit fixing member 314 and connected to the proximal end of the fifth conduit 212 for evacuating the gas in the fifth conduit 212.

Referring to fig. 21, 22 and 24, the prosthesis delivery system further includes a positioning release assembly 40 mounted to the distal end of the positioning catheter assembly 22. The positioning and releasing assembly 40 includes a clamp arm 41 and a control arm 42. The proximal end of the holding arm 41 is fixed to the distal end of the second conduit 221, and the distal end of the holding arm 41 has a holding jaw 411, and the holding jaw 411 is adapted to hold the proximal end of the positioning frame 201.

The proximal end of the control arm 42 is fixed to the distal end of the third catheter 222, and the distal end of the control arm 42 has a control sheath 421. The holding arm 41 is slidably mounted on the control sleeve 421, and moving the control sleeve 421 relative to the holding arm 41 can control the holding jaw 411 to switch between a first holding state and a first releasing state, in the first releasing state, the holding jaw 411 releases the positioning frame 201, and in the first holding state, the holding jaw 411 clamps the positioning frame 201.

Preferably, the number of the clamping arms 41 and the number of the control arms 42 are respectively more than two, and the clamping arms and the control arms are symmetrically arranged to clamp the positioning frame 201 at different positions, so that the stress stability of the positioning frame 201 is improved, and the implantation accuracy is improved. By way of example and not limitation, the number of the gripping arms 41 and the control arms 42 is three, respectively.

In a modified embodiment, the proximal ends of two or more of the gripping arms 41 are integrally connected to each other, and the proximal ends of two or more of the control arms 42 are also integrally connected to each other, so that the two or more of the gripping arms 41 and the two or more of the control arms 42 can be easily connected to the stent catheter assembly 21.

Referring to fig. 21 and 22, the prosthesis delivery system further includes a stent release assembly 50 mounted to the distal end of the stent catheter assembly 21. The stent release assembly 50 includes a distal sleeve 51 and a bayonet joint 52. The bayonet 52 is fixed to the distal end of the fourth catheter tube 211, and the distal end of the fifth catheter tube 212 extends into the distal sleeve 51 and is fixedly connected to the distal end of the distal sleeve 51. The peripheral side of the snap joint 52 has a snap groove 521 for accommodating the snap of the distal end of the bracket 202, and the snap joint 52 is telescopically mounted on the distal end sleeve 51.

The bracket release assembly 50 has a second clamping state and a second release state, in the second clamping state, the snap head 52 is located in the distal end sleeve 51, the snap at the distal end of the bracket 202 is located in the snap groove 521, and the distal end sleeve 51 covers the opening of the snap groove 521 to radially limit the snap; in the second release state, the distal sleeve 51 is moved distally to expose the latch 52, the bracket 202 is expanded, and the latch is disengaged from the latch groove 521.

Referring to fig. 23, the catching groove 521 includes a first section groove 5211 and a second section groove 5212. The first-section groove 5211 is disposed along the circumferential direction of the bayonet 52, the second-section groove 5212 is disposed along the axial direction of the bayonet 52, and the width of the second-section groove 5212 is smaller than the width of the catch at the distal end of the holder 202. The bracket 202 can be axially limited by the first and second grooves 5211 and 5212, and the thickness of the stack of the clip and the bayonet 52 can be reduced by adequately accommodating different positions of the clip.

Referring to fig. 25, the prosthesis 200 further includes a connection rod 203. The proximal end of the connecting rod 203 is connected to the proximal end of the positioning frame 201, and the distal end of the connecting rod 203 is connected to the proximal end of the bracket 202. In the implantation process, the positioning frame 201 is implanted to a preset position and released, and then the proximal end of the bracket 202 is controlled to move into the positioning space of the positioning frame 201 and move to the preset position in the proximal direction. The connecting rod 203 can be bent continuously during the movement of the bracket 202.

Before the distal end of the catheter mechanism 20 moves to the preset position, the distal end sleeve 51 is sleeved outside the stent 202 in the constrained state, the distal end of the bending adjusting catheter 23 is sleeved outside the positioning frame 201 in the constrained state, and the proximal end of the distal end sleeve 51 abuts against the distal end of the bending adjusting catheter, so that the volume of the artificial prosthesis in the implantation process can be reduced, and the artificial prosthesis is prevented from contacting with the outside.

After the distal end of the catheter mechanism 20 is moved to the preset position, the second knob 332 is rotated to control the bending catheter 23 to move towards the proximal end to expose the positioning frame 201, and the positioning frame 201 is radially expanded; rotating the implant housing 13 relative to the bending housing 12 to adjust the positioning frame 201 to a proper angle for accurate positioning to the sinus floor; the fourth knob 315 is turned to control the fourth guide tube 211 and the fifth guide tube 212 to move proximally to drive the proximal end of the bracket 202 to move to a preset position in the positioning space of the positioning frame 201; rotating the fifth knob 316 to control the fifth guide tube 212 to drive the distal sleeve 51 to move distally, so that the snap-fit groove 521 of the snap-fit connector 52 is exposed outside the distal sleeve 51, the stent 202 expands radially, the distal snap of the stent 202 is released from the snap-fit groove 521, and the native valve is located between the stent 202 and the positioning frame 201; the third knob 323 is rotated to control the third catheter 222 to move proximally, so as to drive the control sleeve 421 to move proximally relative to the clamping arm 41, the positioning release assembly 40 is switched to the first release state, and the clamping jaw 411 releases the proximal end of the positioning element 201, thereby achieving complete separation of the artificial prosthesis 200 from the artificial prosthesis delivery system.

It should be noted that before the snap groove 521 of the snap joint 52 is exposed out of the distal sleeve 51, the stent 202 and the positioning frame 201 can be recovered to the distal sleeve 51 and the distal end of the bending catheter 23 and then released, so as to increase the repeated positioning capability, improve the safety during the operation, and facilitate the popularization and application. Illustratively, when the stent 202 and the positioning frame 201 need to be recovered, turning the fifth knob 316 causes the fifth catheter 212 and the distal sleeve 51 to move proximally, so that the stent 202 and the positioning frame 201 are constrained into the distal sleeve 51; rotating the third knob 323 to drive the third catheter 222 and the control sleeve 421 to move distally, so as to push the clamping jaw 411 to clamp the proximal end of the positioning member 201; the second knob 332 is rotated to drive the bending adjusting catheter 23 to move to the distal end and to be sleeved on the outer side of the positioning member 201.

It should be noted that the above embodiments can be freely combined as necessary. The foregoing is only a preferred embodiment of the present invention, and it should be noted that it is obvious to those skilled in the art that various modifications and improvements can be made without departing from the principle of the present invention, and these modifications and improvements should also be considered as the protection scope of the present invention.

Claims (14)

1. An artificial prosthesis delivery system, the artificial prosthesis comprising a spacer and a stent, the delivery system comprising:

a housing having a mounting channel;

the catheter mechanism comprises a stent catheter component, a positioning catheter component and a bending catheter which are sleeved with each other, the stent is arranged at the distal end of the stent catheter component, and the positioning frame is arranged at the distal end of the positioning catheter component;

the control mechanism comprises a bracket control assembly, a positioning control assembly and a bending adjusting control assembly which are arranged on the shell, the near end of the bending adjusting catheter is arranged on the installation channel and is connected with the bending adjusting control assembly, and the bending adjusting control assembly is used for controlling bending adjustment of the bending adjusting catheter and release of the positioning frame; the proximal end of the stent catheter component and the proximal end of the positioning catheter component extend into the mounting channel respectively, the proximal end of the stent catheter component is connected to the stent control component, the proximal end of the positioning catheter component is connected to the positioning control component, the stent control component is used for controlling the distal action of the stent catheter component to control the positioning and releasing of the stent, and the positioning control component is used for controlling the distal action of the positioning catheter component to control the positioning and releasing of the positioning frame.

2. The prosthesis delivery system of claim 1, wherein the housing comprises a bend adjustment housing and an implant housing, a distal end of the implant housing rotatably mounted to a proximal end of the bend adjustment housing, a proximal end of the bend adjustment catheter extending to the bend adjustment housing, and proximal ends of the stent catheter assembly and the positioning catheter assembly extending to the implant housing, wherein rotating the implant housing relative to the bend adjustment housing rotates the distal ends of the stent catheter assembly and the positioning catheter assembly to adjust the angle of the stent and the positioning frame.

3. The prosthesis delivery system of claim 2, further comprising a rotation limiter mounted at a junction of the bend adjustment housing and the implant housing, the rotation limiter having a rotational state in which the implant housing is rotatable relative to the bend adjustment housing and a limiting state; in the limiting state, the rotation limiting part can limit the implant shell and the bending adjusting shell.

4. The prosthesis delivery system according to claim 3, wherein the rotation limiting member comprises a first limiting member fixed to the proximal end of the bend adjusting housing, a second limiting member movably mounted to the implant housing, and an operating member; in the limiting state, the second limiting piece abuts against the first limiting piece; in the rotating state, the first limiting piece and the second limiting piece are separated; the operating part is connected to the second locating part, and the operating part can drive the second locating part to move so as to control the rotating locating part to be switched between the rotating state and the limiting state.

5. The prosthesis delivery system according to claim 4, wherein the first retaining member is a latch fixed to the bending adjustment housing, the second retaining member is a latch fixed to the operating member, the implant housing has a movable opening, and an end of the operating member remote from the second retaining member extends out of the movable opening; the rotation limiting part further comprises an elastic part, and the elastic part abuts against the operating part; in the limiting state, the clamping block is clamped on the clamping tooth, and the elastic piece is in an initial state; pressing the operating piece to compress the elastic piece, separating the clamping block from the clamping tooth, and switching the rotation limiting piece to the rotation state; and when the operating piece is loosened, the elastic piece can push the fixture block to return.

6. The prosthesis delivery system according to claim 5, wherein the number of the operation members of the rotation limiting members, the number of the second limiting members, and the number of the elastic members are two, two of the operation members and two of the second limiting members are symmetrically mounted on the implantation housing, two ends of the two elastic members abut against the two operation members, and an avoidance space for the stent catheter assembly and the positioning catheter assembly to pass through is formed between the two elastic members arranged at intervals.

7. The prosthesis delivery system of claim 3, wherein the rotational stop comprises a first self-locking thread secured to the bend adjustment housing and a second self-locking thread secured to the implant housing, the first self-locking thread being in threaded engagement with the second self-locking thread.

8. The prosthesis delivery system of any one of claims 2-7, wherein the bend tuning housing comprises a first housing and a second housing, the mounting channel corresponding to the first housing is a first channel, the mounting channel corresponding to the second housing is a second channel, and the proximal end of the first housing is telescopically mounted to the second channel;

the first housing has a first rotating portion having a first slide hole communicating with the first passage, the second housing has a second rotating portion having a second slide hole communicating with the second passage;

the bending adjusting control assembly comprises a first knob, a second knob and a first traction piece, the first traction piece is movably arranged in the first channel, and a second traction piece is fixed at the near end of the first shell;

the end parts of the first traction piece and the second traction piece respectively extend out of the first sliding hole and the second sliding hole, the first knob is rotatably sleeved on the first rotating part and connected to the end part of the first traction piece, the second knob is rotatably sleeved on the second rotating part and connected to the end part of the second traction piece, the first knob can be rotated to drive the first traction piece to axially move, and the second knob can be rotated to drive the first shell to axially move; the proximal end of the bending adjusting catheter is fixed to the first shell, and the proximal end of the bending adjusting pull wire of the bending adjusting catheter is fixed to the first traction piece.

9. The prosthesis delivery system of claim 8, wherein the first distraction member includes a distraction body, a distraction tooth mounted to the distraction body, the distraction body having a distraction channel, the bend tuning catheter slidably mounted to the distraction channel.

10. The prosthesis delivery system of claim 9, wherein the sidewall of the pull channel further has an axially extending retention groove in communication with the pull channel, and the proximal end of the bend tuning catheter has an outwardly projecting and axially extending retention projection slidably mounted in the retention groove.

11. The prosthesis delivery system according to any one of claims 2-7, wherein the implant housing comprises a third housing, the mounting channel corresponding to the third housing is a third channel, the third housing comprises a rotational connection section, a second catheter fixing section, a third rotation portion and a third catheter fixing section in sequence from a distal end to a proximal end, and the rotational connection section is rotatably connected to the bend adjusting housing;

the positioning catheter component comprises a second catheter and a third catheter which are sleeved with each other;

the positioning control assembly comprises a second fixing piece, a third traction piece, a third knob and a third fixing piece, the second fixing piece is fixed in the third channel corresponding to the second catheter fixing section, and the proximal end of the second catheter is fixed to the second fixing piece; the third traction piece and the third fixing piece are arranged in the third channel corresponding to the third rotating part, the proximal end of the third catheter is fixedly connected to the third fixing piece, and the third traction piece is fixed to the third fixing piece;

the third rotating portion is provided with a third sliding hole which is communicated with the third channel and axially extends, the end of the third traction piece extends out of the third sliding hole, the third knob is rotatably sleeved on the third rotating portion, the third knob is connected to the end of the third traction piece, and the third traction piece can be driven to drive the third guide pipe to axially move by rotating the third knob.

12. The prosthesis delivery system of claim 11, wherein the proximal end of the third housing further comprises a fourth turning feature, the mounting channel corresponding to the fourth turning feature being a fourth channel;

the implantation shell further comprises a fourth shell, the fourth shell sequentially comprises a telescopic connecting part and a fifth rotating part from a far end to a near end, the telescopic connecting part is telescopically installed in the fourth channel, the installation channel corresponding to the telescopic connecting part is a fifth channel, and the installation channel corresponding to the fifth rotating part is a sixth channel;

the bracket control assembly comprises a fourth traction piece, a fifth traction piece, a fourth fixing piece, a fifth fixing piece, a fourth knob and a fifth knob, the fourth knob is rotatably sleeved on the fourth rotating part, the fifth knob is rotatably sleeved on the fifth rotating part, the fourth traction piece is fixed at the far end of the telescopic connecting part, the fourth fixing piece is fixed on the fifth channel, the fifth traction piece and the fifth fixing piece are movably arranged on the sixth channel, and the fifth traction piece is connected to the fifth fixing piece;

the stent catheter assembly comprises a fourth catheter and a fifth catheter which are sleeved with each other, the proximal end of the fourth catheter is fixed on the fourth fixing piece, and the proximal end of the fifth catheter is fixed on the fifth fixing piece;

the fourth rotating part is provided with a fourth sliding hole communicated with the fourth channel, the end part of the fourth traction piece extends out of the fourth sliding hole, the fourth knob is rotatably sleeved on the fourth rotating part and is connected to the end part of the fourth traction piece, and the fourth knob can be rotated to drive the fourth traction piece, the fourth fixing piece, the fourth shell and the stent catheter assembly to synchronously and axially move;

the fifth rotating part is provided with a fifth sliding hole communicated with the sixth channel, the end part of the fifth traction piece extends out of the fifth sliding hole, the fifth knob is rotatably sleeved on the fifth rotating part and connected to the end part of the fifth traction piece, and the fifth knob can be rotated to drive the fifth traction piece, the fifth fixing piece and the fifth guide pipe to move axially.

13. The prosthesis delivery system of claim 12, further comprising a positioning release assembly mounted to a distal end of the positioning catheter assembly, the positioning release assembly including a clamp arm and a control arm, a proximal end of the clamp arm being secured to a distal end of the second catheter, a distal end of the clamp arm having a clamping jaw adapted to clamp a proximal end of the positioning frame;

the proximal end of the control arm is fixed at the distal end of the third catheter, and the distal end of the control arm is provided with a control sleeve;

the clamping arm is slidably mounted on the control sleeve, the control sleeve can be moved relative to the clamping arm to control the clamping jaws to be switched between a first clamping state and a first releasing state, the clamping jaws loosen the positioning frame in the first releasing state, and the clamping jaws clamp the positioning frame in the first clamping state.

14. The prosthesis delivery system of claim 13, further comprising a stent release assembly mounted to a distal end of the stent catheter assembly, the stent release assembly including a distal sleeve and a bayonet joint, the bayonet joint being secured to a distal end of the fourth catheter, a distal end of the fifth catheter extending into the distal sleeve and being fixedly attached to a distal end of the distal sleeve;

the clamping groove is formed in the periphery of the clamping joint and used for accommodating the buckle at the far end of the bracket, and the clamping joint is telescopically arranged on the far-end sleeve;

the support release assembly is provided with a second clamping state and a second release state, in the second clamping state, the clamping joint is located in the far-end sleeve, the buckle at the far end of the support is located in the clamping groove, and the far-end sleeve covers the opening of the clamping groove to limit the buckle;

in the second release state, the clamping groove of the clamping connector moves to the outer side of the far-end sleeve, and the support expands to enable the buckle to be separated from the clamping groove.

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