CN115414023A - Intracranial pressure monitoring system and time drift correction method of intracranial pressure sensor - Google Patents
Intracranial pressure monitoring system and time drift correction method of intracranial pressure sensor Download PDFInfo
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Abstract
The invention provides an intracranial pressure monitoring system and a time drift correction method of an intracranial pressure sensor, wherein the system comprises: intracranial pressure sensors, intracranial pressure monitors; the intracranial pressure sensor is used for collecting data; the intracranial pressure monitor is connected with the intracranial pressure sensor, a time drift correction module is loaded on the intracranial pressure monitor, and the time drift correction module corrects intracranial pressure data generated according to the collected data according to a prestored time drift correction function; wherein the time drift correction function is previously acquired by simulating an intracranial environment. The invention accurately obtains the time drift correction function in advance by simulating the intracranial environment, is used for correcting the measured intracranial pressure data in actual measurement, improves the accuracy of the intracranial pressure data, and does not need to replace and implant the intracranial pressure sensor under the condition of long-time monitoring.
Description
Technical Field
The invention relates to the field of physiological parameter detection, in particular to an intracranial pressure monitoring system and a time drift correction method of an intracranial pressure sensor.
Background
Current intracranial pressure monitoring product is implanting encephalically after, because of unable direct contact pressure sensor calibrates it, along with the increase of implantation time, pressure sensor's error can increase, and in order to control intracranial pressure detection's precision, partial producer can restrict the time that pressure sensor implanted and not exceed 6 days, to the patient that needs long-term detection, then need implant pressure sensor again, has increased the risk of patient operation infection.
The invention provides an intracranial pressure monitoring system and a time drift correction method of an intracranial pressure sensor, aiming at the defects that the measurement precision of intracranial pressure is reduced along with the increase of time measurement, the process of re-implanting a pressure sensor is complicated and the cost is high in the prior art.
Disclosure of Invention
The invention provides an intracranial pressure monitoring system and a time drift correction method of an intracranial pressure sensor, which are used for solving the defects that the measurement precision of the intracranial pressure sensor is reduced along with the increase of monitoring time length and the intracranial pressure sensor needs to be replaced under the condition of long-time monitoring in the prior art.
The invention provides an intracranial pressure monitoring system, comprising:
intracranial pressure sensors, intracranial pressure monitors;
the intracranial pressure sensor is used for collecting data;
the intracranial pressure monitor is connected with the intracranial pressure sensor, a time drift correction module is loaded on the intracranial pressure monitor, and the time drift correction module corrects intracranial pressure data generated according to the collected data according to a pre-stored time drift correction function; wherein the time drift correction function is previously acquired by simulating an intracranial environment.
According to the intracranial pressure monitoring system provided by the invention, the time drift correction function is obtained by the following steps:
placing an intracranial pressure sensor in a simulated intracranial environment, and acquiring actually measured intracranial pressure data according to a preset time interval under a set pressure condition;
generating an offset error according to the set pressure condition and the measured intracranial pressure data;
and generating the time drift correction function according to the offset error and the acquisition time of the measured intracranial pressure data.
The invention also provides a time drift correction method of the intracranial pressure sensor, which comprises the following steps:
acquiring preliminary intracranial pressure data and generating time of the preliminary intracranial pressure data;
determining a corresponding drift amount according to the generation time of the preliminary intracranial pressure data and combining a time drift correction function; wherein the time drift correction function is previously acquired by simulating an intracranial environment;
and correcting the preliminary intracranial pressure data according to the drift amount.
According to the time drift correction method of the intracranial pressure sensor, provided by the invention, the time drift correction function is obtained by the following method:
placing an intracranial pressure sensor in a simulated intracranial environment, and acquiring actually measured intracranial pressure data according to a preset time interval under a set pressure condition;
generating an offset error according to the set pressure condition and the measured intracranial pressure data;
and generating the time drift correction function according to the offset error and the acquisition time of the measured intracranial pressure data.
According to the method for correcting the time drift of the intracranial pressure sensor, the method for generating the time drift correction function according to the offset error and the acquisition time of the measured intracranial pressure data comprises the following steps:
generating a series of discrete points by taking the offset error as a vertical coordinate and the acquisition time of the corresponding actually measured intracranial pressure data as a horizontal coordinate;
and obtaining the time drift correction function by utilizing least square fitting according to the series of discrete points.
According to the time drift correction method of the intracranial pressure sensor, provided by the invention, the simulated intracranial environment is artificial cerebrospinal fluid with preset PH value, preset osmotic pressure and preset temperature.
According to the time drift correction method of the intracranial pressure sensor, the range of the preset PH value is 7.31-7.35, the range of the preset osmotic pressure is 280-320mmol/L, and the range of the preset temperature is 36.5-37.2 ℃.
According to the time drift correction method of the intracranial pressure sensor, the set pressure condition is taken from 5-15mmHg.
According to the time drift correction method of the intracranial pressure sensor, the simulated intracranial environment is measured in parallel by using a plurality of intracranial pressure sensors, and the actually measured intracranial pressure data is obtained by eliminating abnormal values and calculating an average value.
The invention also provides an electronic device comprising a memory, a processor and a computer program stored on the memory and operable on the processor, wherein the processor executes the program to implement all or part of the steps of the method for correcting the time drift of the intracranial pressure sensor.
According to the intracranial pressure monitoring system and the time drift correction method of the intracranial pressure sensor, the time drift correction function is accurately obtained in advance through simulating an intracranial environment and is used for correcting measured intracranial pressure data in actual measurement, the accuracy of the intracranial pressure data is improved, the intracranial pressure sensor does not need to be replaced and re-implanted under the condition of long-time monitoring, the infection risk of a patient is reduced, and the monitoring accuracy of the intracranial pressure sensor is improved.
Drawings
In order to more clearly illustrate the technical solutions of the present invention or the prior art, the drawings needed for the description of the embodiments or the prior art will be briefly described below, and it is obvious that the drawings in the following description are some embodiments of the present invention, and those skilled in the art can also obtain other drawings according to the drawings without creative efforts.
FIG. 1 is a schematic structural diagram of an intracranial pressure monitoring system provided by the present invention;
FIG. 2 is a schematic flow chart of a method for correcting time drift of an intracranial pressure sensor, provided by the present invention;
FIG. 3 is a schematic diagram of an intracranial pressure sensor offset error measurement apparatus provided by the present invention;
FIG. 4 is a schematic structural diagram of an electronic device provided by the present invention;
reference numerals:
31: a pressure pipe;
32: a transverse tube;
33: a temperature control water tank;
34: an intracranial pressure sensor;
35: a three-way valve;
36: a liquid pumping pipe;
37: a pressure regulating valve;
38: a container.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the technical solutions of the present invention will be clearly and completely described below with reference to the accompanying drawings, and it is obvious that the described embodiments are some, but not all embodiments of the present invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
The environment that the sensor is located has lasting influence to the electrical property of sensor, especially intracranial complicated biochemical environment for the zero point of intracranial sensor or sensitivity change slowly with time, intracranial pressure sensor's error can increase along with the time lapse, often can appear in clinic continuously monitoring intracranial pressure and reach the condition for 2 weeks, for this reason, usually need change, implants intracranial pressure sensor again, and the change process has increased the risk of patient's operation infection. Therefore, the invention provides a time drift correction method of an intracranial pressure sensor and an intracranial pressure monitoring system.
An intracranial pressure monitoring system and a method for correcting time drift of an intracranial pressure sensor according to the present invention will be described with reference to fig. 1 to 4.
Fig. 1 is a schematic structural diagram of an intracranial pressure monitoring system provided by the present invention, as shown in fig. 1, the system includes: an intracranial pressure sensor 11, an intracranial pressure monitor 12;
the intracranial pressure sensor 11 is used for collecting data;
the intracranial pressure monitor 12 is connected to the intracranial pressure sensor 11, the intracranial pressure monitor 12 is loaded with a time drift correction module 121, and the time drift correction module 121 corrects intracranial pressure data generated according to the acquired data according to a pre-stored time drift correction function; wherein the time drift correction function is previously acquired by simulating an intracranial environment.
Specifically, the intracranial pressure sensor 11 is configured to acquire data of a target environment, and transmit the data to the intracranial pressure monitor 12 in a wired or wireless manner, and the intracranial pressure monitor 12 receives and acquires the data transmitted by the intracranial pressure sensor 11, and then performs processing (for example, signal amplification, sampling, and the like) to obtain preliminary intracranial pressure data. The intracranial monitor 12 is loaded with a time drift correction module, which can call a pre-stored time drift correction function to correct the intracranial pressure data, and the time drift correction function is obtained by simulating the intracranial environment in advance.
In the embodiment, the time drift correction function is accurately obtained in advance by simulating the intracranial environment, so that the measured intracranial pressure data is corrected in actual measurement, the accuracy of the intracranial pressure data is improved, the intracranial pressure sensor does not need to be replaced and re-implanted under the condition of long-time monitoring, the infection risk of a patient is reduced, and the monitoring precision of the intracranial pressure sensor is improved.
Based on the above embodiments, in one embodiment, the time drift correction function is obtained by:
placing an intracranial pressure sensor in a simulated intracranial environment, and acquiring actually measured intracranial pressure data according to a preset time interval under a set pressure condition;
generating an offset error according to the set pressure condition and the measured intracranial pressure data;
and generating the time drift correction function according to the offset error and the acquisition time of the measured intracranial pressure data.
The time drift correction function is obtained in advance through simulating an intracranial environment, the simulated intracranial environment is a test environment established by referring to a liquid environment in human cranium, pressure conditions (namely accurate intracranial pressure data) can be set in the simulated intracranial environment, actual intracranial pressure of the intracranial pressure sensor in the simulated intracranial environment under different duration is observed, offset errors (namely corresponding drift amounts) of the intracranial pressure sensor under corresponding duration are determined by comparing the set pressure conditions with the actual intracranial pressure data, and then the corresponding time drift correction function of the intracranial pressure sensor is fitted according to the offset errors of the intracranial pressure sensor under each duration.
It should be noted that, the time for acquiring the measured intracranial pressure data is equivalent to the duration of the intracranial pressure sensor in the target environment, and can be obtained by subtracting the time for completing the implantation of the intracranial pressure sensor from the time for acquiring the intracranial pressure sensor data.
In the embodiment, the time drift correction function is accurately obtained in advance by simulating the intracranial environment and is stored in the intracranial pressure monitor, and the intracranial pressure monitor corrects the measured intracranial pressure data by using the stored time drift correction function through the loading time drift correction module in actual measurement, so that the accuracy of the intracranial pressure data is improved, and the intracranial pressure sensor does not need to be replaced and re-implanted under the condition of long-time monitoring.
The invention also provides a time drift correction method of the intracranial pressure sensor, and the time drift correction method of the intracranial pressure sensor described below and the intracranial pressure monitoring system described above can be referred to correspondingly.
Fig. 2 is a schematic flow chart of a method for correcting time drift of an intracranial pressure sensor, as shown in fig. 2, the method includes:
s21, acquiring primary intracranial pressure data and generating time of the primary intracranial pressure data;
specifically, the execution subject of the method is equipment, and more specifically, the execution subject is an intracranial pressure monitor. After the intracranial pressure sensor collects data, the data to which the data are transmitted to the intracranial pressure monitor, and the data can be transmitted in a wired mode or in a wireless mode (for example, bluetooth, wiFi, zigBee, NFC and the like). After receiving and acquiring data transmitted by the intracranial pressure sensor, the intracranial pressure monitor performs processing (such as signal amplification, sampling and the like) to obtain preliminary intracranial pressure data. The preliminary intracranial pressure is the intracranial pressure data to be corrected, which may have a deviation, and the magnitude of the deviation is related to the duration of time that the intracranial pressure sensor is in the target environment, and for this reason, the generation time of the preliminary intracranial pressure data is also needed to be acquired.
It should be noted that, the generation time of the preliminary intracranial pressure data herein is equivalent to the duration of the intracranial pressure sensor in the target environment, and can be obtained by subtracting the implantation completion time of the intracranial pressure sensor from the acquisition time of the corresponding intracranial pressure sensor data.
S22, determining a corresponding drift amount according to the generation time of the preliminary intracranial pressure data and by combining a time drift correction function; wherein the time drift correction function is previously acquired by simulating an intracranial environment;
specifically, since each intracranial pressure data has a corresponding generation time, the time that the intracranial pressure sensor continues to measure in the target environment can be determined accordingly. The time-drift function is a plot of the amount of intracranial pressure drift (i.e., the deviation of the intracranial pressure measurement) as a function of time. By simulating an intracranial environment, the intracranial pressure sensor is used for simulating and measuring the intracranial pressure under a set condition, and the drift amount of the measurement value of the intracranial pressure sensor under the set condition can be determined, so that a time drift function corresponding to the intracranial pressure sensor can be fitted. It can be understood that after the time drift correction function is obtained, the corresponding drift amount can be directly determined according to the continuous measurement time of the intracranial pressure sensor in the target environment in the actual measurement process of the intracranial pressure.
And S23, correcting the preliminary intracranial pressure data according to the drift amount.
Specifically, on the basis of the preliminary intracranial pressure data, the corrected intracranial pressure data can be obtained by compensating the preliminary intracranial pressure data by using the corresponding drift amount.
In the embodiment, the time drift correction function is accurately obtained in advance by simulating the intracranial environment, so that the measured intracranial pressure data is corrected in actual measurement, the accuracy of the intracranial pressure data is improved, the intracranial pressure sensor does not need to be replaced and re-implanted under the condition of long-time monitoring, the infection risk of a patient is reduced, and the monitoring precision of the intracranial pressure sensor is improved.
Based on any one of the above embodiments, in an embodiment, the time drift correction function is obtained by:
placing an intracranial pressure sensor in a simulated intracranial environment, and acquiring actually measured intracranial pressure data according to a preset time interval under a set pressure condition;
generating an offset error according to the set pressure condition and the measured intracranial pressure data;
and generating the time drift correction function according to the offset error and the acquisition time of the measured intracranial pressure data.
In particular, the simulated intracranial environment is a test environment established with reference to the fluid environment within the human cranium. When acquiring the time drift correction function, firstly setting pressure conditions (namely accurate intracranial pressure data) for the simulated intracranial environment, observing actually-measured intracranial pressure of the intracranial pressure sensor under different duration in the simulated intracranial environment, determining offset error (namely corresponding drift amount) of the intracranial pressure sensor under corresponding duration by comparing the set pressure conditions with the actually-measured intracranial pressure data, and then fitting the corresponding time drift correction function of the intracranial pressure sensor according to the corresponding offset error of the intracranial pressure sensor under each duration.
In addition, the preset time interval can be set according to requirements, for example, data is collected once after the intracranial pressure sensor is implanted, then data is collected once every minute, and data is collected once every 5 minutes for example. The total collection time can be set according to requirements, for example, 30 days of data are collected.
In the embodiment, the time drift correction function is more suitable for the requirement of intracranial pressure measurement by simulating the intracranial environment, the offset error of the intracranial pressure sensor under each continuous measurement time is accurately determined by setting the pressure condition and acquiring actually-measured intracranial pressure data according to the preset time interval, and the time drift correction function is conveniently and accurately acquired.
In one embodiment, based on any of the above embodiments, the generating the time drift correction function according to the offset error and the acquisition time of the measured intracranial pressure data includes:
generating a series of discrete points by taking the offset error as a vertical coordinate and the corresponding acquisition time of the actually measured intracranial pressure data as a horizontal coordinate;
and obtaining the time drift correction function by utilizing least square fitting according to the series of discrete points.
Specifically, a series of discrete points can be obtained in a coordinate system by taking an offset error (i.e., an offset amount) as a vertical coordinate and taking a corresponding measured intracranial pressure data generation time (i.e., a duration time of the sensor in a target environment) as a vertical coordinate; then, a time drift function (curve) of the intracranial pressure sensor is fitted by using a least square method according to the series of discrete points, wherein the specific fitting function type is a polynomial function, a logarithmic function and the like.
In the embodiment, a time drift correction curve is accurately fitted by using a least square method by acquiring a series of offset errors and corresponding acquisition time of actually measured intracranial pressure data as discrete points, so that the intracranial pressure data can be corrected conveniently, and the accuracy of intracranial pressure detection is improved.
Based on any one of the above embodiments, in one embodiment, the simulated intracranial environment is artificial cerebrospinal fluid with a preset PH, a preset osmotic pressure and a preset temperature.
Specifically, cerebrospinal fluid is a colorless and transparent liquid that fills the ventricles of the brain, the subarachnoid space, and the central canal of the spinal cord. The artificial cerebrospinal fluid contains similar components as cerebrospinal fluid, such as chloride, sodium, magnesium, ethanol, protein, urea nitrogen, creatinine, uric acid, amino acids, glucose, calcium, lactic acid, acetone, enzyme, etc. The influence of the intracranial environment on the sensor can be more accurately simulated by adjusting the pH value, the osmotic pressure and the temperature of the artificial cerebrospinal fluid to a preset range, and a more accurate time drift correction function is obtained.
In the embodiment, the artificial cerebrospinal fluid with the preset pH value, the preset osmotic pressure and the preset temperature simulates an intracranial environment, so that chemical and physical conditions similar to those of a real intracranial environment are achieved, the influence of the intracranial environment on the sensor can be simulated more accurately, and a more accurate time drift correction function is obtained.
Based on any one of the embodiments, in one embodiment, the preset pH value ranges from 7.31 to 7.35, the preset osmotic pressure ranges from 280 mmol/L to 320mmol/L, and the preset temperature ranges from 36.5 ℃ to 37.2 ℃.
Specifically, the pH value of the artificial cerebrospinal fluid is adjusted to be in the range of 7.31 to 7.34 (for example, 7.31, 7.32, 7.33, 7.34 and the like, preferably 7.32), the osmotic pressure is adjusted to be in the range of 280 to 320mmol/L (for example, 285mmol/L, 295mmol/L, 310mmol/L,/315 mmol/L and the like, preferably 295 mmol/L), the temperature of the artificial cerebrospinal fluid is adjusted to be in the range of 36.5 to 37.2 ℃ (for example, 36.5 ℃, 36.7 ℃, 36.9 ℃, 37.1 ℃, 37.2 ℃ and the like, preferably 37 ℃), and by adjusting the physical/chemical parameters of the artificial cerebrospinal fluid to be in the parameter range, a stable simulated environment which is more consistent with the real intracranial condition can be obtained, and the accuracy of the time drift correction function is further improved.
In one embodiment, the set pressure condition is 5 to 15mmHg based on any one of the embodiments.
Specifically, the set pressure condition is the "real intracranial pressure" in the simulated intracranial environment that is accurately controlled, and is also a comparison object of the intracranial pressure actually measured by the intracranial pressure sensor, and is a reference for determining the offset error of the intracranial pressure sensor. The set pressure condition is set to be 5-15mmHg, for example, 5mmHg, 7mmHg, 10mmHg, 13mmHg, 15mmHg and the like are taken, so that the simulated intracranial environment is more consistent with the intracranial pressure environment of the human body, and a more accurate time drift correction function is convenient to obtain.
Based on any one of the embodiments, in one embodiment, the simulated intracranial environment is measured in parallel by using a plurality of intracranial pressure sensors, and the measured intracranial pressure data is obtained by eliminating abnormal values and calculating an average value.
Specifically, a single intracranial pressure sensor may cause inaccurate measurement due to accidental factors, pressure data are measured in parallel by a plurality of intracranial pressure sensors under the same set pressure condition in a simulated intracranial environment, abnormal values in the pressure data are eliminated, and actual measurement intracranial pressure data which are more accurate, stable and higher in reliability are obtained by means of averaging.
Fig. 3 shows a schematic diagram of an intracranial pressure sensor offset error measuring device, as shown in fig. 3, with a vertical pressure tube 31 connected to a first end of a transverse tube 32, and a second end of the transverse tube 32 in a temperature-controlled water tank 33. A temperature-controlled water tank 33 holds a liquid (e.g., water) to maintain the second end of cross tube 32 at a set temperature. The pipeline of manometer pipe 31 and violently pipe 32 is the connected state, the second end of violently pipe 32 is the enclosed state, namely, the inside liquid environment that does not communicate in with accuse temperature water tank 33 of the pipeline of violently pipe 32 second end, the second end of violently pipe 32 still is provided with intracranial pressure sensor 34, artificial cerebrospinal fluid has in manometer pipe 31 and the pipeline of violently pipe 32, intracranial pressure sensor 34 can be used for measuring the pressure data of the artificial cerebrospinal fluid in violently pipe 32 second end pipeline, the centre of violently pipe 32 still is equipped with three-way valve 35, pump liquid pipe 36 is connected to the third end of three-way valve 35, be equipped with air-vent valve 37 (for example, the peristaltic pump) on the pump liquid pipe 36, can be through controlling air-vent valve 37 decision and be in the pipeline with the artifical cerebrospinal fluid pump in the container 38, set pressure condition with the environment in the regulation simulation cranium.
Fig. 4 illustrates a physical structure diagram of an electronic device, which may include, as shown in fig. 4: a processor (processor) 410, a communication Interface 420, a memory (memory) 430 and a communication bus 440, wherein the processor 410, the communication Interface 420 and the memory 430 are communicated with each other via the communication bus 440. Processor 410 may invoke logic instructions in memory 430 to perform all or a portion of the steps of each of the provided intracranial pressure sensor time drift correction methods described above.
Finally, it should be noted that: the above examples are only intended to illustrate the technical solution of the present invention, and not to limit it; although the present invention has been described in detail with reference to the foregoing embodiments, it will be understood by those of ordinary skill in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some technical features may be equivalently replaced; and such modifications or substitutions do not depart from the spirit and scope of the corresponding technical solutions of the embodiments of the present invention.
Claims (10)
1. An intracranial pressure monitoring system, comprising: intracranial pressure sensors, intracranial pressure monitors;
the intracranial pressure sensor is used for collecting data;
the intracranial pressure monitor is connected with the intracranial pressure sensor, a time drift correction module is loaded on the intracranial pressure monitor, and the time drift correction module corrects intracranial pressure data generated according to the collected data according to a pre-stored time drift correction function; wherein the time drift correction function is previously acquired by simulating an intracranial environment.
2. An intracranial pressure monitoring system as claimed in claim 1, wherein the time-drift correction function is obtained by:
placing an intracranial pressure sensor in a simulated intracranial environment, and acquiring actually measured intracranial pressure data according to a preset time interval under a set pressure condition;
generating an offset error according to the set pressure condition and the measured intracranial pressure data;
and generating the time drift correction function according to the offset error and the acquisition time of the measured intracranial pressure data.
3. A method for correcting time drift of an intracranial pressure sensor, comprising:
acquiring preliminary intracranial pressure data and generating time of the preliminary intracranial pressure data;
determining a corresponding drift amount according to the generation time of the preliminary intracranial pressure data and combining a time drift correction function; wherein the time drift correction function is previously acquired by simulating an intracranial environment;
and correcting the preliminary intracranial pressure data according to the drift amount.
4. The method according to claim 3, wherein said time drift correction function is obtained by:
placing an intracranial pressure sensor in a simulated intracranial environment, and acquiring actually measured intracranial pressure data according to a preset time interval under a set pressure condition;
generating an offset error according to the set pressure condition and the measured intracranial pressure data;
and generating the time drift correction function according to the offset error and the acquisition time of the measured intracranial pressure data.
5. The method according to claim 4, wherein said generating said time drift correction function based on said offset error and said measured intracranial pressure data acquisition time comprises:
generating a series of discrete points by taking the offset error as a vertical coordinate and the acquisition time of the corresponding actually-measured intracranial pressure data as a horizontal coordinate;
and obtaining the time drift correction function by utilizing least square fitting according to the series of discrete points.
6. The method for correcting time drift of an intracranial pressure sensor as recited in claim 4, wherein the simulated intracranial environment is artificial cerebrospinal fluid with a preset pH value, a preset osmotic pressure, and a preset temperature.
7. The method for correcting time drift of an intracranial pressure sensor as claimed in claim 6, wherein the preset pH is in the range of 7.31 to 7.35, the preset osmotic pressure is in the range of 280 to 320mmol/L, and the preset temperature is in the range of 36.5 to 37.2 ℃.
8. The method for correcting time drift of an intracranial pressure sensor as recited in claim 6, wherein the set pressure is selected from the range of 5 to 15mmHg.
9. The method of correcting time drift of intracranial pressure sensors, according to claim 4, wherein the simulated intracranial environment is measured in parallel using a plurality of intracranial pressure sensors, and the measured intracranial pressure data is obtained by eliminating abnormal values and averaging.
10. An electronic device comprising a memory, a processor and a computer program stored on the memory and executable on the processor, wherein the processor when executing the computer program implements all or part of the steps of the method for time drift correction of an intracranial pressure sensor as recited in any one of claims 3 to 9.
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