CN115381381B - Endoscope device - Google Patents

Endoscope device Download PDF

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Publication number
CN115381381B
CN115381381B CN202211314821.3A CN202211314821A CN115381381B CN 115381381 B CN115381381 B CN 115381381B CN 202211314821 A CN202211314821 A CN 202211314821A CN 115381381 B CN115381381 B CN 115381381B
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light
dispersion
lens
beam splitter
different
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CN115381381A (en
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王璞
杨雪芳
马丁昽
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Beihang University
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Beihang University
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00163Optical arrangements
    • A61B1/00194Optical arrangements adapted for three-dimensional imaging
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/04Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances
    • A61B1/05Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances characterised by the image sensor, e.g. camera, being in the distal end portion
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/06Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
    • A61B1/0638Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements providing two or more wavelengths

Abstract

The application provides an endoscope device, which comprises a light source, a dispersion stretching device, a dispersion micro-lens and a detector, wherein the light source is used for emitting broad-spectrum pulse light, the dispersion stretching device is used for carrying out dispersion stretching treatment on the broad-spectrum pulse light so as to output dispersion stretching light with different wavelengths at different positions of a time domain, and then the dispersion micro-lens emits the dispersion stretching light to an interested object, wherein the axial focusing positions of the dispersion micro-lens on the light with different wavelengths are different; finally, the detector receives the light signal reflected by the object of interest for constructing a three-dimensional image. By adopting the method, the multi-depth simultaneous imaging of the interested object can be realized, the single photon detection can be realized, the mechanical axial scanning is not needed, the line scanning speed of the traditional CCD is not limited, and the imaging speed is higher.

Description

Endoscope device
Technical Field
The application relates to the technical field of medical photonics, in particular to an endoscope device.
Background
With the development of medical technology, endoscopic microscopes are widely used in the medical field. The traditional reflection confocal microscope is excited by single-wavelength light, and only a specific tissue depth can be imaged under the excitation of the single-wavelength light. Thus, conventional reflective confocal microscopes can only image one depth plane at a time.
In this way, if 3D imaging needs to be completed, axial scanning needs to be performed by a mechanical scanning device, and the imaging speed is slow.
Disclosure of Invention
In view of the above, it is necessary to provide an endoscope apparatus having a high imaging speed in order to solve the above-described problems.
The application provides an endoscope device, which comprises a light source, a dispersion stretching device, a dispersion micro-lens and a detector; a light source for emitting broad-spectrum pulsed light; the dispersion stretching device is used for carrying out dispersion stretching treatment on the broad-spectrum pulse light so as to output dispersion stretched light, and the wavelengths of the dispersion stretched light at different positions of a time domain are different; the dispersion micro-lens is used for emitting dispersion stretching light to the interested object, wherein the axial focusing positions of the dispersion micro-lens to the light with different wavelengths are different; a detector for receiving the light signals reflected by the object of interest, the light signals reflected by the object of interest being used for constructing a three-dimensional image of the object of interest.
In one embodiment, the dispersion stretching device comprises two opposing silver mirrors, with a first predetermined angle between the two silver mirrors.
In one embodiment, the endoscope apparatus further comprises a first beam splitter, a grating, and a first lens group, the first lens group comprising at least one lens, the first beam splitter being disposed on an emission light path of the broad-spectrum pulsed light; the grating, the first lens group and the dispersion stretching device are all arranged on a transmission light path of the first beam splitter, the grating is located between the first beam splitter and the first lens group, and the first lens group is located between the grating and the dispersion stretching device.
In one embodiment, the endoscope apparatus further comprises a second beam splitter disposed on a reflected light path of the first beam splitter; the dispersion micro-lens is arranged on a transmission light path of the second beam splitter, and the detector is arranged on a reflection light path of the second beam splitter.
In one embodiment, the endoscopic device further comprises a first objective lens disposed in an optical path between the second beam splitter and the detector.
In one embodiment, the endoscopic device further comprises an aperture disposed in the optical path between the first objective lens and the detector.
In one embodiment, the endoscope apparatus further comprises a two-dimensional scanning device disposed on the optical path between the second beam splitter and the dispersive micro-lens; and the two-dimensional scanning device is used for adjusting the emergent direction of the dispersed and stretched light from the dispersed micro-lens.
In one embodiment, the two-dimensional scanning device includes two opposite scanning mirrors and a driving device, and the driving device is configured to drive the scanning mirrors to turn according to a second preset angle.
In one embodiment, the endoscopic device further comprises a second lens group comprising two lenses, and a mirror; the second lens group and the reflecting mirror are arranged on a light path between the second beam splitter and the dispersive micro-lens.
In one embodiment, the endoscopic device further comprises a second objective lens and a fiber bundle; the second objective lens is positioned between the two-dimensional scanning device and the optical fiber bundle; and the optical fiber bundle is positioned between the second objective lens and the dispersive micro-lens.
In one embodiment, the endoscopic device further comprises a high speed acquisition system; and the high-speed acquisition system is used for acquiring the output of the detector and reconstructing a three-dimensional image of the interested object in real time.
The application provides an endoscope device, which comprises a light source, a dispersion stretching device, a dispersion micro-lens and a detector, wherein the light source is used for emitting broad-spectrum pulse light, the dispersion stretching device is used for carrying out dispersion stretching treatment on the broad-spectrum pulse light so as to output dispersion stretching light with different wavelengths at different positions of a time domain, and then the dispersion micro-lens emits the dispersion stretching light to an interested object, wherein the axial focusing positions of the dispersion micro-lens on the light with different wavelengths are different; finally, the detector receives the light signal reflected by the object of interest for constructing a three-dimensional image. In this way, the broad-spectrum pulsed light is stretched in time by the dispersion stretching device, so that light with different wavelengths is distributed in different time, then the dispersion micro-lens focuses light with different wavelengths to different positions in the axial direction of the interested object, then the detector receives light signals reflected by the interested object, and as the light with different wavelengths corresponds to different time, the light with different wavelengths focuses to different positions in the axial direction of the interested object, the light with different time corresponds to different positions in the axial direction of the interested object, namely, the signals with different time carry information of different depths of the interested object, therefore, three-dimensional information of the interested image can be directly obtained, axial mechanical scanning is not needed, meanwhile, single photon detection is carried out by the detector, imaging speed is not limited due to the limitation of traditional CCD line scanning speed, and therefore, the imaging speed is faster.
Drawings
FIG. 1 is a schematic view of an embodiment endoscopic device;
FIG. 2 is a schematic view of an endoscopic device in another embodiment;
FIG. 3 is a schematic view of an endoscopic device in another embodiment;
FIG. 4 is a schematic view of an endoscopic device in another embodiment;
FIG. 5 is a schematic view of an endoscopic device in another embodiment;
FIG. 6 is a schematic view of an endoscopic device in another embodiment;
fig. 7 is a schematic view of an endoscopic apparatus in another embodiment.
Description of reference numerals:
11. a light source; 12. A dispersion stretching device; 13. A dispersive micro-lens;
14. a detector; 21. A first beam splitter; 22. A grating;
23. a first lens group; 31. A second beam splitter; 32. A cylindrical lens;
41. a first objective lens; 42. A pinhole 51, a two-dimensional scanning device;
61. a second lens group; 62. A mirror 63, a second objective lens;
64. an optical fiber bundle.
Detailed Description
In order to make the objects, technical solutions and advantages of the present application more apparent, the present application is described in further detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the present application and are not intended to limit the present application.
In the present application, the terms "first", "second" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include at least one such feature. It will be understood that when an element is referred to as being "disposed on" another element, it can be directly on the other element or intervening elements may also be present.
The application provides an endoscope device, which comprises a light source, a dispersion stretching device, a dispersion micro-lens and a detector, wherein the light source is used for emitting broad-spectrum pulse light, the dispersion stretching device is used for carrying out dispersion stretching treatment on the broad-spectrum pulse light so as to output dispersion stretching light with different wavelengths at different positions of a time domain, and then the dispersion micro-lens emits the dispersion stretching light to an interested object, wherein the axial focusing positions of the dispersion micro-lens on the light with different wavelengths are different; finally, the detector receives the light signal reflected by the object of interest for constructing a three-dimensional image. Because the light with different wavelengths corresponds to different time, and the light with different wavelengths is focused to different positions of the interested object in the axial direction, the light with different time corresponds to different positions of the interested object in the axial direction, namely, signals with different time carry information of different depths of the interested object, thereby directly obtaining three-dimensional information of an interested image without axial mechanical scanning, simultaneously carrying out single photon detection by a detector, and having no imaging speed limitation caused by the limited line scanning speed of the traditional CCD, therefore, the imaging speed is faster.
Fig. 1 is a block diagram showing a configuration of an endoscope apparatus according to an embodiment of the present invention. As shown in fig. 1, the endoscope apparatus includes a light source 11, a dispersive stretching device 12, a dispersive microlens 13, and a detector 14; a light source 11 for emitting broad-spectrum pulsed light; a dispersion stretching device 12, configured to perform dispersion stretching processing on the broad-spectrum pulse light to output dispersion stretched light, where wavelengths of the dispersion stretched light at different positions in a time domain are different; a dispersive micro-lens 13 for emitting dispersive stretching light to the object of interest, wherein the axial focusing positions of the dispersive micro-lens 13 for light of different wavelengths are different; a detector 14 for receiving the light signals reflected by the object of interest, the light signals reflected by the object of interest being used for constructing a three-dimensional image of the object of interest.
The light source 11 is configured to emit broad-spectrum pulsed light, where the broad-spectrum pulsed light includes light with multiple wavelengths. The broad spectrum pulsed light is stretched by a dispersion stretching device 12, the dispersion stretching device 12 may be a Free-space angular chirp-enhanced delay (FACED) device, and the pulse width may be ps (10) -12 Second) broad spectrum pulse light is subjected to time stretching to reach ns (10) -9 Seconds) to meet the response frequency detected by the detector. The dispersion stretched light is light processed by the dispersion stretching device 12, and the wavelengths of the broad-spectrum pulsed light at different positions of the time domain are different after the broad-spectrum pulsed light is stretched by the dispersion stretching device 12, that is, the light with different wavelengths corresponds to different times, so that the time stretching is realized. The chromatic dispersion micro lens 13 emits the processed chromatic dispersion stretching light to the interested object, and the chromatic dispersion micro lens 13 has large axial chromatic aberration, so that the light with different wavelengths can be focused at different positions in the axial direction, namely the light with different wavelengths is focused at different depths of the interested object, and the light signal reflected from the interested object returns along the original path and is received by the detector 14.
The detector 14 may be a single photon detector, and may convert an optical signal into an electrical signal for output, and may receive the optical signal of a single photon and then convert the optical signal into an electrical signal for output, where the intensity of the output electrical signal is proportional to the intensity of the optical signal. Since different wavelengths of light correspond to different depths and different wavelengths of light correspond to different times, the different times of light received by the detector 14 correspond to different depths in the axial direction of the object of interest and may be used to construct a three-dimensional image of the image of interest.
In this embodiment, the endoscope apparatus includes a light source, a dispersion stretching device, a dispersion micro-lens, and a detector, where the light source is configured to emit broad-spectrum pulsed light, the dispersion stretching device is configured to perform dispersion stretching processing on the broad-spectrum pulsed light to output dispersion stretched light with different wavelengths at different positions of a time domain, and then the dispersion micro-lens emits the dispersion stretched light to an object of interest, where axial focusing positions of the dispersion micro-lens on the light with different wavelengths are different; finally, the detector receives the light signal reflected by the object of interest for constructing a three-dimensional image. In this way, the broad-spectrum pulsed light is stretched in time by the dispersion stretching device, so that light with different wavelengths is distributed in different time, then the dispersion micro-lens focuses light with different wavelengths to different positions in the axial direction of the interested object, then the detector receives light signals reflected by the interested object, and as the light with different wavelengths corresponds to different time, the light with different wavelengths focuses to different positions in the axial direction of the interested object, the light with different time corresponds to different positions in the axial direction of the interested object, namely, the signals with different time carry information of different depths of the interested object, therefore, three-dimensional information of the interested image can be directly obtained, axial mechanical scanning is not needed, meanwhile, single photon detection is carried out by the detector, imaging speed is not limited due to the limitation of traditional CCD line scanning speed, and therefore, the imaging speed is faster.
In an alternative embodiment, as shown in fig. 2, the endoscope apparatus further includes a first beam splitter 21, a grating 22, and a first lens group 23, the first lens group 23 includes at least one lens, the first beam splitter 21 is disposed on an emission optical path of the broad-spectrum pulsed light; the grating 22, the first lens group 23 and the dispersion stretching device 12 are all disposed on the transmission light path of the first beam splitter 21, and the grating 22 is located between the first beam splitter 21 and the first lens group 23, and the first lens group 23 is located between the grating 22 and the dispersion stretching device 12.
The first beam splitter 21 is located on an emission light path of the broad spectrum pulse light source, and is capable of splitting the broad spectrum pulse light into a plurality of beams of light, the first beam splitter 21 has transmission and reflection characteristics, and the grating 22, the first lens group 23, and the dispersion stretching device 12 are all disposed on the transmission light path of the first beam splitter 21. Meanwhile, the grating 22 is located between the first beam splitter 21 and the first lens group 23, as shown in fig. 2, may include 2 lenses, both of which are located between the grating 22 and the dispersion stretching device 12. The broad spectrum pulse light is transmitted through the first beam splitter 21 to reach the grating 22, the grating 22 disperses light with different wavelengths in the broad spectrum pulse light, and then the light passes through two lenses of the first lens group 23, and the first lens group 23 focuses the light and enters the dispersion stretching device 12.
The dispersive stretching device 12 comprises two opposing silver mirrors with a first predetermined angle between them.
Optionally, the dispersion stretching device 12 is composed of two opposite silver reflectors, a first preset angle is formed between the two silver reflectors, the first preset angle is a tiny angle, and adjustment can be performed, by adjusting parameters and angles of the two silver reflectors, so that angles at which light with different wavelengths in the broad-spectrum pulsed light dispersed by the grating 22 enters the dispersion stretching device 12 are different, and therefore paths of light with different wavelengths reflected back and forth between the two silver reflectors of the dispersion stretching device 12 are different. The light can be reflected back to the original path by adjusting the slight angle formed between the two silver mirrors of the dispersion drawing device 12. At this time, the light with different wavelengths forms a time delay difference due to the difference of the reflection paths, and the light with different wavelengths corresponds to different times, thereby realizing time stretching.
In the above embodiment, the dispersion stretching device is used to stretch the broad-spectrum pulse light in time, and the light with different wavelengths is corresponding to different times, so as to satisfy the response frequency of the detector.
In one embodiment, as shown in fig. 3, the endoscope apparatus further includes a second beam splitter 31, the second beam splitter 31 being disposed on the reflection optical path of the first beam splitter 21; the dispersive microlens 13 is disposed on the transmission light path of the second beam splitter 31, and the detector 14 is disposed on the reflection light path of the second beam splitter 31.
The second beam splitter 31 has transmission and reflection characteristics, the second beam splitter 31 is located on the reflection optical path of the first beam splitter 21, the light reflected by the dispersion stretching device 12 returns along the original path, is reflected by the first beam splitter 21 to reach the second beam splitter 31, and reaches the dispersion microlens 13 through the transmission optical path of the second beam splitter 31. The dispersive micro-lens 13 focuses light with different wavelengths at different depths of the object of interest, and then the signal reflected by the object of interest returns to the original path, passes through the second beam splitter 31 again, and then passes through the reflection optical path of the second beam splitter 31, and the detector 14 is located on the reflection optical path of the second beam splitter 31, so as to perform signal detection on the signal reflected by the object of interest.
Optionally, with continued reference to fig. 3, a cylindrical lens 32 may be further included between the first beam splitter 21 and the second beam splitter 31, and the cylindrical lens 32 may correct the light.
In one embodiment, as shown in fig. 4, the endoscopic device further includes a first objective lens 41, the first objective lens 41 being disposed on the optical path between the second beam splitter 31 and the detector 14.
Wherein the signal reflected back by the object of interest reaches the first objective lens 41 through the reflected optical path of the second beam splitter 31, and the first objective lens 41 focuses the reflected signal light.
Optionally, with continued reference to fig. 4, the endoscopic device further comprises an aperture 42, the aperture 42 being disposed in the optical path between the first objective lens 41 and the detector 14.
Optionally, an aperture 42 is added in front of the detector 14, the aperture 42 is a confocal aperture, the first objective 41 focuses the reflected signal light, and then the reflected signal light passes through the aperture 42, and the aperture 42 can block stray light, thereby avoiding interference of the stray light to the reflected signal.
In one embodiment, as shown in fig. 5, the endoscopic device further includes a two-dimensional scanning device 51, the two-dimensional scanning device 51 being disposed on the optical path between the second beam splitter 31 and the dispersive microlens 13; and a two-dimensional scanning device 51 for adjusting the emission direction of the dispersed and stretched light from the dispersive microlens 13.
The two-dimensional scanning device 51 includes two opposite scanning mirrors and a driving device, and the driving device is configured to drive the scanning mirrors to turn over according to a second preset angle.
Optionally, the driving device may be a driving motor, the two scanning mirrors of the two-dimensional scanning device 51 are driven by the motor to turn over according to a second preset angle, and the exit angle of the light passing through the two-dimensional scanning device 51 can be changed by changing the angle of the scanning mirrors, so that the exit direction of the light of the dispersive micro-lens 13 can be adjusted, the light can be focused on different horizontal positions of the interested object through the dispersive micro-lens 13, and the scanning of the whole two-dimensional plane of the interested image can be realized.
In one embodiment, as shown in fig. 6, the endoscopic device further includes a second lens group 61 and a reflecting mirror 62, the second lens group 61 including two lenses; the second lens group 61 and the mirror 62 are both disposed on the optical path between the second beam splitter 31 and the dispersive micro-lens 13.
Among them, the second lens group 61 includes 2 lenses, as shown in fig. 6, and can perform beam collimation and relay on incoming light. The second lens group 61 is disposed between the two-dimensional scanning device 51 and the second objective lens 63. The distance between the first lens of the second lens group 61 and the two-dimensional scanning device 51 is the focal length of the first lens, the distance between the first lens and the second lens of the second lens group 61 is the sum of the focal lengths of the first lens and the second lens, and the distance between the second lens of the second lens group 61 and the second objective lens 63 is the focal length of the second lens group 61.
The mirror 62 is used to change the direction of the light in the optical path, and as shown in fig. 6, may include 2 mirrors, one located on the optical path between the second beam splitter 31 and the second lens group 61, and the other located on the optical path between the second lens group 61 and the dispersive micro-lens 13.
In an alternative embodiment, continuing to refer to FIG. 6, the endoscopic device further includes a second objective 63 and a fiber optic bundle 64; a second objective lens 63 located between the two-dimensional scanning device 51 and the optical fiber bundle 64; and the optical fiber bundle 64 is positioned between the second objective lens 63 and the dispersive micro-lens 13.
Wherein the second objective lens 63 is located on the optical path between the two-dimensional scanning device 51 and the optical fiber bundle 64, the second objective lens 63 focuses and couples the stretched broad spectrum pulse light into the optical fiber bundle 64 of the endoscope device, and the broad spectrum pulse light is transmitted in the optical fiber bundle 64 and then focused onto the object of interest by the dispersive micro-lens 13.
In one embodiment, the endoscopic device further comprises a high speed acquisition system; and the high-speed acquisition system is used for acquiring the output of the detector and reconstructing a three-dimensional image of the interested object in real time.
Optionally, the high-speed acquisition system may be a digitizer or a real-time oscilloscope with a high sampling rate and a high bandwidth, and the acquisition of the output of the detector is performed, so that the signals at different times carry information of the object of interest at different axial depths, and therefore, the reconstruction of a three-dimensional image of the object of interest in real time can be realized without mechanically performing axial scanning.
Further, the entire structure of the endoscope apparatus is shown in fig. 7. The broad spectrum pulse light emitted by the light source 11 is transmitted to the grating 22 through the first beam splitter 21, the grating 22 disperses light with different wavelengths, then the light is transmitted to the dispersion stretching device 12 through the first lens group 23, the dispersion stretching device 12 stretches the broad spectrum pulse light in time, the light with different wavelengths is stretched by the dispersion stretching device 12 and then is distributed in different times, then the light returns to the first beam splitter 21 in the original path and is reflected to the second beam splitter 31, the light is transmitted through the second beam splitter 31, the direction of the light is changed by the reflector 62, the light is focused and coupled into the optical fiber bundle 64 by the second objective 63, the light with different wavelengths is focused by the dispersion micro-lens 13 at different depths of an interested object, the interested object can be transversely scanned in two dimensions through the two-dimensional scanning device 51, finally, the signal reflected from the interested object is detected through the detector 14, and then the signal acquisition and real-time 3D image reconstruction are performed through the high-speed acquisition system. In this process, the pulse emission of the broad-spectrum pulsed light, the frame scanning of the two-dimensional scanning device, and the signal acquisition need to be synchronized.
The technical features of the above embodiments can be arbitrarily combined, and for the sake of brevity, all possible combinations of the technical features in the above embodiments are not described, but should be considered as the scope of the present specification as long as there is no contradiction between the combinations of the technical features.
The above-mentioned embodiments only express several embodiments of the present application, and the description thereof is more specific and detailed, but not construed as limiting the scope of the present application. It should be noted that, for a person skilled in the art, several variations and modifications can be made without departing from the concept of the present application, which falls within the scope of protection of the present application. Therefore, the protection scope of the present application should be subject to the appended claims.

Claims (11)

1. An endoscope device is characterized by comprising a light source, a dispersion stretching device, a dispersion micro lens and a single photon detector;
the light source is used for emitting broad-spectrum pulsed light;
the dispersion stretching device is used for performing dispersion stretching treatment on the broad-spectrum pulse light to output dispersion stretched light, and the wavelengths of the dispersion stretched light at different positions of a time domain are different;
the dispersive micro-lens is used for emitting the dispersive stretching light to an interested object, wherein the axial focusing positions of the dispersive micro-lens on the light with different wavelengths are different so that the light with different wavelengths corresponds to different axial depths;
the single photon detector is used for receiving the single photon optical signals reflected by the interested object, wherein the single photon optical signals at different times carry different axial depths of the interested object based on the light with different wavelengths distributed at different positions of a time domain and corresponding to the different axial depths, and the single photon optical signals reflected by the interested object are used for constructing a three-dimensional image of the interested object.
2. An endoscopic device as defined in claim 1, wherein the dispersive stretching device comprises two opposing silver mirrors with a first predetermined angle therebetween.
3. The endoscopic device of claim 2, further comprising a first beam splitter, a grating, and a first lens group comprising at least one lens, the first beam splitter disposed on an emission light path of the broad-spectrum pulsed light;
the grating, the first lens group and the dispersion stretching device are all arranged on a transmission light path of the first beam splitter, the grating is located between the first beam splitter and the first lens group, and the first lens group is located between the grating and the dispersion stretching device.
4. The endoscopic device of claim 3 further comprising a second beam splitter disposed in a reflected light path of the first beam splitter;
the dispersion micro lens is arranged on a transmission light path of the second beam splitter, and the single photon detector is arranged on a reflection light path of the second beam splitter.
5. The endoscopic device of claim 4 further comprising a first objective lens disposed in the optical path between said second beam splitter and said single photon detector.
6. The endoscopic device of claim 5 further comprising an aperture disposed in the optical path between said first objective lens and said single photon detector.
7. The endoscopic device of claim 4 further comprising a two-dimensional scanning device disposed in the optical path between the second beam splitter and the dispersive microlens;
and the two-dimensional scanning device is used for adjusting the emergent direction of the dispersion stretching light from the dispersion micro-lens.
8. The endoscopic device as defined in claim 7, wherein the two-dimensional scanning device comprises two oppositely disposed scanning mirrors and a driving device for driving the scanning mirrors to turn according to a second preset angle.
9. The endoscopic device of claim 7 further comprising a second lens group comprising two lenses and a mirror;
the second lens group and the reflector are both arranged on a light path between the second beam splitter and the dispersive micro-lens.
10. The endoscopic device of claim 7 further comprising a second objective lens and a fiber optic bundle;
the second objective lens is positioned between the two-dimensional scanning device and the optical fiber bundle;
the optical fiber bundle is positioned between the second objective lens and the dispersive micro-lens.
11. The endoscopic device of claim 1 further comprising a high speed acquisition system;
the high-speed acquisition system is used for acquiring the output of the single photon detector and reconstructing a three-dimensional image of the interested object in real time.
CN202211314821.3A 2022-10-26 2022-10-26 Endoscope device Active CN115381381B (en)

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107534261A (en) * 2015-03-31 2018-01-02 港大科桥有限公司 Space chirp chamber for stretching/compressing optical pulse in time
CN111981973A (en) * 2020-09-23 2020-11-24 渭南师范学院 Quick frequency sweep OCT system of frequency sweep light source
CN112666698A (en) * 2021-01-27 2021-04-16 之江实验室 Dispersive super-surface-based fiber bundle multi-azimuth three-dimensional confocal imaging device and method
CN114812427A (en) * 2022-04-22 2022-07-29 重庆大学 Ultrafast imaging system with nanometer resolution

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2628456T3 (en) * 2011-09-26 2017-08-02 Wavelight Gmbh Optical Coherence Tomography Technique
US10222607B2 (en) * 2016-12-14 2019-03-05 Canon U.S.A., Inc. Three-dimensional endoscope
CN108303421B (en) * 2018-01-02 2020-02-11 清华大学 Three-dimensional high-speed wide-field tomography method and device
CN108593605B (en) * 2018-04-23 2020-02-28 清华大学 Three-dimensional high-speed wide-field tomography method and device
TWI718805B (en) * 2019-12-11 2021-02-11 財團法人工業技術研究院 Endoscope stereo imaging device
CN113008851B (en) * 2021-02-20 2024-04-12 大连海事大学 Device for improving weak signal detection signal-to-noise ratio of confocal structure based on oblique-in excitation

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107534261A (en) * 2015-03-31 2018-01-02 港大科桥有限公司 Space chirp chamber for stretching/compressing optical pulse in time
CN111981973A (en) * 2020-09-23 2020-11-24 渭南师范学院 Quick frequency sweep OCT system of frequency sweep light source
CN112666698A (en) * 2021-01-27 2021-04-16 之江实验室 Dispersive super-surface-based fiber bundle multi-azimuth three-dimensional confocal imaging device and method
CN114812427A (en) * 2022-04-22 2022-07-29 重庆大学 Ultrafast imaging system with nanometer resolution

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