CN115364358A - Face-beautifying small needle positive healing technology - Google Patents
Face-beautifying small needle positive healing technology Download PDFInfo
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- CN115364358A CN115364358A CN202110555272.8A CN202110555272A CN115364358A CN 115364358 A CN115364358 A CN 115364358A CN 202110555272 A CN202110555272 A CN 202110555272A CN 115364358 A CN115364358 A CN 115364358A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/728—Hyaluronic acid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1808—Epidermal growth factor [EGF] urogastrone
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00743—Type of operation; Specification of treatment sites
- A61B2017/00747—Dermatology
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0061—Methods for using microneedles
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Abstract
The invention provides a face-beautifying small needle forward healing technology, and relates to the technical field of medical treatment. The face beautifying small needle positive healing technology comprises the following processes: s1, firstly carrying out allergy test on a therapist according to a collagen filler required by the therapist, and ensuring no adverse reaction. The invention provides a face-beautifying small needle positive healing technology, which is characterized in that injection stock solution prepared from autologous collagen of a patient is injected into subcutaneous tissue to be widely spread on a periosteum layer and a subcutaneous fat layer to form a large-area wound surface, collagen meshes are respectively formed on the two separated layers of tissue wound surfaces by utilizing the self blood coagulation property of the collagen, and then a cavity is closed by depending on the adhesiveness of the collagen to achieve the effects of tissue thickening and positive healing.
Description
Disclosure of Invention
Technical problem to be solved
Aiming at the defects of the prior art, the invention provides a face beautifying small needle positive healing technology, and solves the problem of self-healing of skin.
(II) technical scheme
In order to achieve the purpose, the invention is realized by the following technical scheme: the face beautifying microneedle positive healing technology comprises the following steps:
s1, allergy detection
Firstly, carrying out allergy test on a therapist according to a collagen filler required by the therapist, and ensuring that adverse reactions do not exist;
s2, cleaning injection part
Cleaning the skin surface of a part needing injection by using a cleaning agent;
s3, preparing raw materials
(1) Disinfecting the skin of the patient;
(2) Collecting blood for a patient using venous draw;
(3) The collected blood of a patient enters a whole blood separator after being centrifuged for the first time, and is centrifuged for the second time in the whole blood separator, the whole blood is divided into three layers, namely a plasma layer, a leucocyte layer and a red blood cell layer from top to bottom;
(4) Introducing the liquid of the plasma layer, the white blood membrane layer and the red blood cell layer into different storage units through catheters for separate storage, taking out a proper amount of the liquid of the plasma layer and the liquid of the white blood membrane layer from the storage units, mixing the liquid of the plasma layer and the liquid of the white blood membrane layer in proportion, and carrying out primary purification through a chromatography unit and further purification through a diafiltration unit to obtain the required autologous collagen;
(5) Fully mixing the autologous collagen with the stem cell suspension, the hyaluronic acid solution, the epidermal growth factor solution, the antioxidant molecules, the normal saline and the like according to a proportion to prepare an injection stock solution;
s4, disinfection
Cleaning the skin part to be injected of the patient by using a disinfectant;
s5, anesthetic injection
The anesthetic needle is used for injecting the skin part of the patient needing collagen injection, so that the local skin tissue of the patient is anesthetized, and pain of the patient is reduced;
s6, protein injection
A doctor injects autologous collagen to a patient by using a medical cosmetic needle, particularly the doctor holds the cosmetic needle by hand, the needle point of the cosmetic needle sequentially penetrates through the stratum corneum, the epidermis and the dermis of the skin of the patient and penetrates into the skin tissue of the patient all the time, then the autologous collagen is injected into the skin tissue of the patient by using external force or the cosmetic needle by means of a medical instrument, the cosmetic needle is pulled out after the injection is finished, and the needle hole on the skin is cleaned, disinfected and subjected to hemostasis treatment;
s7. Ice compress
The ice bag and other objects are used for icing the skin injection part of a patient, so that slight and temporary discomfort at the skin injection part can be effectively relieved.
Preferably, the detergent in step S2 may be made of normal saline.
Preferably, the disinfectant in step S4 may be iodophor or 75% alcohol, and if iodophor is used for disinfection, the subsequent deiodination with alcohol is also required.
Preferably, the beauty maintaining needle in the step S6 is composed of a needle head and a needle handle, and is an integral structure.
Preferably, the small face-beautifying needle is made of medical stainless steel materials with the diameter of 40-50 micrometers.
Preferably, the autologous collagen prepared in step S3 needs to be homogenized by a homogenizer so that the collagen can pass through a needle of 40 μm or less in size.
Preferably, the needle opening position of the small facial appearance needle during injection is positioned between the periosteum layer and the subcutaneous fat layer.
Preferably, the method is short in the whole operation process, and does not need complicated operations such as incision.
(III) advantageous effects
The invention provides a face beautifying small needle positive healing technology. The method has the following beneficial effects:
1. the invention provides a face-beautifying small needle forward healing technology, which comprises the steps of utilizing autologous collagen of a patient to be fully mixed with stem cell suspension, hyaluronic acid solution, epidermal growth factor solution, antioxidant molecules, normal saline and the like according to a proportion to prepare injection stock solution, injecting the injection stock solution into subcutaneous tissues to widely pad bone membranous layers and subcutaneous fat layers to form large-area wound surfaces, utilizing the blood coagulation property of the collagen to respectively form collagen nets on two separated tissue wound surfaces, closing cavities by the adhesion of the collagen to achieve the effects of tissue thickening and forward healing, having good effect on the autologous growth of large-range tissues, and having natural connection and transition with surrounding tissues.
2. The invention provides a face-beautifying small needle forward healing technology which is simple to operate, simplifies the complicated steps of the traditional tissue healing and repairing operation, does not need operation and micro-wound, saves time, has good repairing effect and no side effect, and is worthy of vigorous popularization.
3. The invention provides a face-beautifying small needle positive healing technology, which adopts micro needles as thin as hair to perform operation, has small wound area, and simultaneously has good healing property and natural effect because of adopting self-repairing growing skin, so that a patient hardly feels pain, and the comfort degree of the patient is improved.
4. The invention provides a face-beautifying small needle forward healing technology which is simple to operate, simple and efficient in process, better in patient experience, capable of effectively avoiding possible risks and wounds caused by traditional operations and safer.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example (b):
the embodiment of the invention provides a face beautifying small needle positive healing technology, which comprises the following steps:
s1, allergy detection
Firstly, carrying out allergy test on a therapist according to a collagen filler required by the therapist, and ensuring that adverse reactions do not exist;
s2, cleaning injection part
Cleaning the skin surface of a part needing injection by using a cleaning agent;
s3, preparing raw materials
(1) Disinfecting the skin of a patient;
(2) Performing a blood collection for a patient using a venous draw;
(3) The collected blood of a patient enters a whole blood separator after being centrifuged for the first time, and is centrifuged for the second time in the whole blood separator, the whole blood is centrifuged and divided into three layers, namely a plasma layer, a leucocyte layer and a red blood cell layer from top to bottom;
(4) Introducing the liquid of the plasma layer, the white blood membrane layer and the red blood cell layer into different storage units through catheters for separate storage, taking out a proper amount of the liquid of the plasma layer and the liquid of the white blood membrane layer from the storage units, mixing the liquid of the plasma layer and the liquid of the white blood membrane layer in proportion, and carrying out primary purification through a chromatography unit and further purification through a diafiltration unit to obtain the required autologous collagen;
(5) Fully mixing the autologous collagen with the stem cell suspension, the hyaluronic acid solution, the epidermal growth factor solution, the antioxidant molecules, the normal saline and the like according to a proportion to prepare an injection stock solution;
s4, disinfection
Cleaning the skin part to be injected of the patient by using a disinfectant;
s5, anesthetic injection
The anesthetic needle is used for injecting the skin part of the patient needing collagen injection, so that the local skin tissue of the patient is anesthetized, and pain of the patient is reduced;
s6. Protein injection
The method comprises the steps that a doctor injects autologous collagen to a patient by using a medical cosmetic needle, specifically, the doctor holds the cosmetic needle by hand, the needle point of the cosmetic needle sequentially penetrates through the horny layer, the epidermal layer and the dermis layer of the skin of the patient, penetrates into the skin tissue of the patient all the time, then injects the autologous collagen into the skin tissue of the patient by using an external force or by using the cosmetic needle with the help of a medical instrument, extracts the cosmetic needle after injection is completed, and performs cleaning, disinfection and hemostasis treatment on a needle hole on the skin, wherein the autologous collagen is widely spread on the periosteum layer and the subcutaneous fat layer respectively to form a large-area wound surface, collagen nets are formed on two separated layers of tissue wound surfaces respectively by using the self-blood coagulation property of the collagen, and then the cavity is closed by depending on the adhesion property of the collagen to achieve the effect of tissue healing in a forward direction, the autologous growth effect of the thickened large-area tissue is good, and the engagement and transition with the surrounding tissue are very natural;
s7. Ice compress
The ice bag and other objects are used for icing the skin injection part of a patient, so that slight and temporary discomfort at the skin injection part can be effectively relieved.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Claims (8)
1. The face beautifying microneedle positive healing technology is characterized in that: the method comprises the following steps:
s1, allergy detection
Firstly, carrying out allergy test on a therapist according to a collagen filler required by the therapist, and ensuring that adverse reactions do not exist;
s2, cleaning injection part
Cleaning the skin surface of a part needing injection by using a cleaning agent;
s3, preparing raw materials
(1) Disinfecting the skin of the patient;
(2) Performing a blood collection for a patient using a venous draw;
(3) The collected blood of a patient enters a whole blood separator after being centrifuged for the first time, and is centrifuged for the second time in the whole blood separator, the whole blood is divided into three layers, namely a plasma layer, a leucocyte layer and a red blood cell layer from top to bottom;
(4) Introducing the liquid of the plasma layer, the white blood membrane layer and the red blood cell layer into different storage units through catheters for separate storage, taking out a proper amount of the liquid of the plasma layer and the liquid of the white blood membrane layer from the storage units, mixing the liquid of the plasma layer and the liquid of the white blood membrane layer in proportion, and carrying out primary purification through a chromatography unit and further purification through a diafiltration unit to obtain the required autologous collagen;
(5) Fully mixing the autologous collagen with the stem cell suspension, the hyaluronic acid solution, the epidermal growth factor solution, the antioxidant molecules, the normal saline and the like according to a proportion to prepare an injection stock solution;
s4, disinfection
Cleaning the skin part to be injected of the patient by using a disinfectant;
s5, anesthetic injection
Injecting the skin part of the patient needing collagen injection by using an anesthetic needle, so that local skin tissues of the patient are anesthetized, and pain of the patient is reduced;
s6. Protein injection
A doctor injects autologous collagen to a patient by using a medical cosmetic needle, particularly the doctor holds the cosmetic needle by hand, the needle point of the cosmetic needle sequentially penetrates through the stratum corneum, the epidermis and the dermis of the skin of the patient and penetrates into the skin tissue of the patient all the time, then the autologous collagen is injected into the skin tissue of the patient by using external force or the cosmetic needle by means of a medical instrument, the cosmetic needle is pulled out after the injection is finished, and the needle hole on the skin is cleaned, disinfected and subjected to hemostasis treatment;
s7. Ice compress
The ice bag and other objects are used for icing the skin injection part of a patient, so that slight and temporary discomfort at the skin injection part can be effectively relieved.
2. The face-beautifying microneedle positive healing technique according to claim 1, wherein: the detergent in step S2 may be made of normal saline.
3. The face-beautifying microneedle positive healing technique according to claim 1, wherein: the disinfectant in the step S4 may be iodophor or 75% alcohol.
4. The face-beautifying microneedle positive healing technique according to claim 1, wherein: the small face beautifying needle in the step S6 is composed of a needle head and a needle handle and is of an integral structure.
5. The face-beautifying microneedle positive healing technique according to claim 1, wherein: the small face-beautifying needle is made of medical stainless steel materials with the diameter of 40-50 micrometers.
6. The face-beautifying microneedle positive healing technique according to claim 1, wherein: the autologous collagen prepared in step S3 needs to be homogenized by a homogenizer so that the collagen can pass through a needle of 40 μm or less in size.
7. The face-beautifying microneedle positive healing technique according to claim 1, wherein: the needle opening position of the small face-beautifying needle during injection is positioned between the periosteum layer and the subcutaneous fat layer.
8. The face microneedle positive healing technique of claims 1-7, wherein: the method is short in time for the whole operation process, and does not need complicated operations such as surgery.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110555272.8A CN115364358A (en) | 2021-05-21 | 2021-05-21 | Face-beautifying small needle positive healing technology |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110555272.8A CN115364358A (en) | 2021-05-21 | 2021-05-21 | Face-beautifying small needle positive healing technology |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN115364358A true CN115364358A (en) | 2022-11-22 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202110555272.8A Pending CN115364358A (en) | 2021-05-21 | 2021-05-21 | Face-beautifying small needle positive healing technology |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN115364358A (en) |
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2021
- 2021-05-21 CN CN202110555272.8A patent/CN115364358A/en active Pending
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