CN115350667A - Medicine midbody reation kettle for pharmaceutical production - Google Patents
Medicine midbody reation kettle for pharmaceutical production Download PDFInfo
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- CN115350667A CN115350667A CN202210867488.2A CN202210867488A CN115350667A CN 115350667 A CN115350667 A CN 115350667A CN 202210867488 A CN202210867488 A CN 202210867488A CN 115350667 A CN115350667 A CN 115350667A
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- 239000003814 drug Substances 0.000 title claims abstract description 24
- 238000004519 manufacturing process Methods 0.000 title claims abstract description 24
- 229940079593 drug Drugs 0.000 title abstract description 10
- 230000007246 mechanism Effects 0.000 claims abstract description 33
- 239000002994 raw material Substances 0.000 claims abstract description 29
- 238000003756 stirring Methods 0.000 claims description 37
- 238000003780 insertion Methods 0.000 claims description 32
- 230000037431 insertion Effects 0.000 claims description 32
- 230000005540 biological transmission Effects 0.000 claims description 26
- 244000309464 bull Species 0.000 claims description 12
- 239000012450 pharmaceutical intermediate Substances 0.000 claims description 10
- 230000001360 synchronised effect Effects 0.000 claims description 10
- 238000001514 detection method Methods 0.000 claims description 7
- 230000003044 adaptive effect Effects 0.000 claims description 5
- 244000208734 Pisonia aculeata Species 0.000 claims description 4
- 230000002093 peripheral effect Effects 0.000 claims description 4
- 230000006978 adaptation Effects 0.000 claims description 3
- 238000007905 drug manufacturing Methods 0.000 claims description 3
- 230000001105 regulatory effect Effects 0.000 claims description 2
- 230000009471 action Effects 0.000 abstract description 7
- 238000009434 installation Methods 0.000 abstract description 5
- 230000008901 benefit Effects 0.000 description 10
- 230000033001 locomotion Effects 0.000 description 10
- 230000000694 effects Effects 0.000 description 9
- 239000000543 intermediate Substances 0.000 description 7
- 238000000034 method Methods 0.000 description 6
- 230000008859 change Effects 0.000 description 4
- 230000008569 process Effects 0.000 description 2
- 238000012545 processing Methods 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 235000017166 Bambusa arundinacea Nutrition 0.000 description 1
- 235000017491 Bambusa tulda Nutrition 0.000 description 1
- 241001330002 Bambuseae Species 0.000 description 1
- 235000015334 Phyllostachys viridis Nutrition 0.000 description 1
- 239000011425 bamboo Substances 0.000 description 1
- 239000013064 chemical raw material Substances 0.000 description 1
- 230000001276 controlling effect Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 230000002194 synthesizing effect Effects 0.000 description 1
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/18—Stationary reactors having moving elements inside
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0053—Details of the reactor
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J4/00—Feed or outlet devices; Feed or outlet control devices
- B01J4/02—Feed or outlet devices; Feed or outlet control devices for feeding measured, i.e. prescribed quantities of reagents
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01K—MEASURING TEMPERATURE; MEASURING QUANTITY OF HEAT; THERMALLY-SENSITIVE ELEMENTS NOT OTHERWISE PROVIDED FOR
- G01K13/00—Thermometers specially adapted for specific purposes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2204/00—Aspects relating to feed or outlet devices; Regulating devices for feed or outlet devices
- B01J2204/002—Aspects relating to feed or outlet devices; Regulating devices for feed or outlet devices the feeding side being of particular interest
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
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- General Physics & Mathematics (AREA)
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Abstract
The invention discloses a drug intermediate reaction kettle for drug production, which relates to the technical field of drug production and comprises a reaction kettle main body, a plurality of feeding pipes and a uniform filling mechanism, wherein the uniform filling mechanism consists of a plurality of quantitative filling components, two vertical support rods are installed at the top of the reaction kettle main body, a support cross rod is installed at the top ends of the two vertical support rods, and a plurality of installation rotating holes are formed in the side part of the support cross rod. According to the invention, when the control knob is rotated, the plurality of filling pistons are driven to simultaneously slide up and down in the plurality of filling cylinders at different distances, and at the moment, under the combined action of the feeding pipe, the feeding pipe and the one-way valve, raw materials can be filled into the reaction kettle main body in an equivalent amount, so that the purpose of measuring and adding various raw materials can be completed at one time, time and labor are saved, the production efficiency is improved, the situation that the quality of a medicine intermediate is influenced due to careless measuring and error can be effectively reduced, and the practicability is good.
Description
Technical Field
The invention relates to the technical field of medicine production, in particular to a medicine intermediate reaction kettle for medicine production.
Background
The medical intermediate is actually a chemical raw material or a chemical product which is high in technical density, high in added value and special in application and is used in the process of synthesizing the medicine; with the continuous improvement of the living standard of people and the continuous updating and upgrading of medicines, the demand on intermediates is more and more increased; in the production of pharmaceutical intermediates, a reaction vessel is generally used.
When using reation kettle to produce medicine midbody, all add various raw materialss according to specific proportion usually, and traditional addition mode is generally got the interpolation to multiple raw materials in proper order, and the operation is wasted time and energy, leads to production efficiency to be lower, and getting the in-process, the condition of mistake is got to careless volume very easily appearing, influences the quality of medicine midbody, for this reason, this application discloses a medicine midbody reation kettle for drug manufacturing satisfies people's demand.
Disclosure of Invention
The utility model aims to provide a medicine midbody reation kettle for drug manufacturing to propose traditional mode of addition among the above-mentioned background art and generally get the interpolation to getting to multiple raw materials in proper order, the operation wastes time and energy, leads to production efficiency to be lower, and gets the in-process at the volume, appears carelessly very easily and gets the problem of mistake and influence medicine midbody quality by volume.
In order to achieve the above purpose, the present application provides the following technical solutions: a drug intermediate reaction kettle for drug production comprises a reaction kettle main body, a plurality of feeding pipes and a uniform filling mechanism, wherein the uniform filling mechanism consists of a plurality of quantitative filling components, two vertical supporting rods are installed at the top of the reaction kettle main body, supporting cross rods are installed at the top ends of the two vertical supporting rods together, a plurality of installation rotating holes are formed in the side portion of each supporting cross rod, driving rotating shafts are installed in the installation rotating holes in a rotating mode, synchronous rotating units are installed at one ends of the driving rotating shafts together, and a fastening unit is installed on one of the driving rotating shafts; the quantitative filling assembly comprises a feeding pipe arranged on the top of the reaction kettle main body, a filling cylinder is arranged at the top end of the feeding pipe, one end of the feeding pipe is arranged on the lateral part of the filling cylinder, one-way valves are fixedly arranged on the feeding pipe and the feeding pipe, a filling piston matched with the feeding pipe is sleeved in the filling cylinder in a sliding mode, a connecting moving rod is arranged at the top of the filling piston, the top end of the connecting moving rod extends out of the filling cylinder and is provided with a reciprocating frame, a driving disc is arranged at one end of the driving rotating shaft, an eccentric rotating rod is eccentrically arranged on the lateral part of the driving disc through an adaptive adjusting unit, and the end part of the eccentric rotating rod penetrates through the reciprocating frame; install in the reation kettle main part and be used for carrying out the rapid mixing mechanism of homogeneous mixing and carry out the temperature-detecting mechanism that removes the detection to reaction temperature to the raw materials, rapid mixing mechanism with temperature-detecting mechanism is connected.
Preferably, the synchronous rotation unit is including installing respectively in a plurality of drive shaft end portion's a plurality of transmission worm wheels, two the dead lever is all installed to the lateral part of vertical stay bar, two the tip of dead lever is all installed and is injectd the bearing, two it installs the control bull stick to inject to cup joint jointly in the bearing, cup joint on the control bull stick and install a plurality of transmission worms, and is a plurality of transmission worm respectively with a plurality of the meshing of drive worm wheel mutually, control knob is installed to the one end of control bull stick.
Preferably, the fastening unit comprises a fastening bolt arranged on the supporting cross rod, a fastening screw hole communicated with one of the mounting rotating holes is formed in the top of the supporting cross rod, the fastening bolt is installed in the fastening screw hole in a threaded manner, and the bottom end of the fastening bolt is attached to one of the driving rotating shafts.
Preferably, the adaptation regulating unit is including seting up bar spout on the drive disc lateral part, rotate on the bottom inner wall of bar spout and install accommodate the lead screw, the adjustment has been cup jointed to the screw thread on the accommodate the lead screw and has been moved the piece, eccentric bull stick is installed on the lateral part that the piece was moved in the adjustment, accommodate the lead screw's top extends to install adjust knob outside the drive disc, install the locking subunit on the adjust knob.
Preferably, the locking sub-unit includes a fixing protrusion installed on an outer peripheral side of the driving disc, an insertion rod sliding hole is formed in a side portion of the fixing protrusion, a locking insertion rod is slidably installed in the insertion rod sliding hole, a plurality of locking insertion holes are uniformly formed in an outer peripheral side of the adjusting knob, one end of the locking insertion rod extends into one of the locking insertion holes, a handle pull block is installed at the other end of the locking insertion rod, and an elastic pull-back element is installed on the handle pull block.
Preferably, the elastic pull-back element comprises a reset tension spring sleeved on the locking insertion rod, and two ends of the reset tension spring are respectively installed on the fixed lug and the side part of the handle pull block.
Preferably, quick stirring mechanism is including installing center sleeve on the inner wall of reation kettle main part top, the rotation fluted disc has been cup jointed in the rotation on the center sleeve, a plurality of rotation holes have evenly been seted up at the top of rotation fluted disc, and are a plurality of all rotate in the rotation hole and install the stirring pivot, and is a plurality of puddlers are evenly installed in the stirring pivot, L shape fixed plate is installed at the top of reation kettle main part, servo motor is installed to the bottom of L shape fixed plate, the motor shaft is installed to servo motor's output, the bottom of motor shaft extends to in the reation kettle main part and install with rotation fluted disc engaged with drive gear, it is a plurality of install removal rotation unit jointly in the stirring pivot, the motor shaft with temperature-detecting mechanism is connected.
Preferably, the mobile rotation unit comprises a plurality of planetary gears which are respectively arranged on the top ends of the plurality of stirring rotating shafts, a plurality of straight rods are uniformly arranged on the inner wall of the top of the reaction kettle main body, a fixed gear ring is jointly arranged at the bottom ends of the plurality of straight rods, and the plurality of planetary gears are all meshed with the fixed gear ring.
Preferably, the temperature detection mechanism is including setting up thermodetector in the reation kettle main part, it changes the hole to have seted up the screw rod on the top inner wall of reation kettle main part, the screw rod changes the downthehole rotation and installs vertical screw rod, the screw thread has cup jointed vertical shifting block on the vertical screw rod, install vertical guide arm on the top inner wall of reation kettle main part, the slip has cup jointed the guide block on the vertical guide arm, vertical shifting block with the guide block symmetry is installed on thermodetector's the periphery side, the motor shaft pass through the pulley drive unit with vertical screw rod is connected.
Preferably, the belt wheel transmission unit comprises two transmission belt wheels which are respectively installed on the motor rotating shaft and the vertical screw in a sleeved mode, and a transmission belt is jointly tensioned and sleeved on the two transmission belt wheels.
In conclusion, the technical effects and advantages of the invention are as follows:
1. according to the invention, when the control knob is rotated, the control rotating rod, the transmission worm and the transmission worm wheel drive the plurality of driving rotating shafts to synchronously rotate, the driving rotating shafts can drive the reciprocating moving frame to reciprocate up and down through the driving disc, the adjusting moving block and the eccentric rotating rod, and further the connecting moving rod can drive the filling piston to slide up and down in the filling cylinder, at the moment, under the combined action of the feeding pipe, the feeding pipe and the one-way valve, raw materials can be filled into the reaction kettle body in an equivalent manner, so that the purpose of measuring and adding various raw materials can be finished at one time, time and labor are saved, the production efficiency is improved, the situation that the quality of a medicine intermediate is influenced due to careless measuring and error can be effectively reduced, and the practicability is good;
2. according to the invention, when the adjusting knob is rotated, the adjusting moving block is driven to move through the adjusting screw rod, the rotating diameter of the eccentric rotating rod can be changed by the movement of the adjusting moving block, and the vertical sliding distance of the filling piston can be further changed, so that the quantity of the added raw materials can be adjusted, the equipment can be used for adding various raw materials in different proportions, and the application range is improved;
3. according to the invention, when the handle pull block is pulled, the locking insertion rod is driven to move out of the locking insertion hole, the adjusting knob is loosened, the adjusting knob can be rotated to perform adjusting operation, when the handle pull block is loosened, the locking insertion rod is driven to be automatically inserted into the locking insertion hole under the action of the elastic force of the reset tension spring, the adjusting knob is fixed all the time, the condition that the raw material adding proportion is changed due to the rotation of the adjusting knob is effectively reduced, and the use is more stable;
4. when the servo motor is started, the rotating fluted disc is driven to rotate by the motor rotating shaft and the driving gear, so that the stirring rotating shaft and the stirring rod can be driven to rotate circumferentially, the purpose of stirring and mixing the raw materials is achieved, meanwhile, the planetary gear can be driven to rotate circumferentially together by the circumferential rotation of the stirring rotating shaft, at the moment, the planetary gear can rotate under the action of the fixed gear ring, so that the stirring rotating shaft can rotate simultaneously in the circumferential rotation process, the stirring effect is further improved, and the raw materials are mixed more uniformly;
5. according to the invention, when the motor rotating shaft rotates, the vertical screw rod can be driven to synchronously rotate through the transmission belt wheel and the transmission belt, and under the common cooperation of the vertical guide rod and the guide block, the vertical screw rod rotates and can drive the temperature detector to vertically move through the vertical moving block, so that the aim of movably detecting the reaction temperature in the reaction kettle main body is fulfilled, the accuracy of a detection result is improved, a worker can better adjust and control the reaction temperature, and the practicability is better.
Drawings
In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments of the present application, and other drawings can be obtained by those skilled in the art without creative efforts.
Fig. 1 is a schematic perspective view of an embodiment of the present application;
FIG. 2 is an enlarged perspective view of a unified filling mechanism in an embodiment of the present application;
fig. 3 is an enlarged schematic perspective view of another view of the unified filling mechanism in the embodiment of the present application;
FIG. 4 is an enlarged partial structural view of a filling barrel in the embodiment of the application;
FIG. 5 is a schematic diagram of a partially enlarged structure of an adaptive adjusting unit in an embodiment of the present application;
FIG. 6 is a schematic view of a partially cut-away structure of a main body of a reaction kettle in an embodiment of the present application;
FIG. 7 is an enlarged view of a portion of the rapid stirring mechanism in the embodiment of the present application;
fig. 8 is a partially enlarged schematic structural view of a temperature detection mechanism in an embodiment of the present application.
In the figure: 1. a reaction kettle main body; 2. a feed pipe; 3. filling a cylinder; 4. a feed tube; 5. a one-way valve; 6. filling a piston; 7. connecting the moving rod; 8. moving the frame to and fro; 9. a vertical stay bar; 10. a support rail; 11. driving the rotating shaft; 12. a drive disk; 13. adjusting the moving block; 14. an eccentric rotating rod; 15. a drive worm gear; 16. defining a bearing; 17. controlling the rotating rod; 18. a drive worm; 19. a control knob; 20. fastening a bolt; 21. adjusting the screw rod; 22. adjusting a knob; 23. fixing the bump; 24. locking the inserted rod; 25. locking the jack; 26. a handle pull block; 27. a return tension spring; 28. a central sleeve; 29. rotating the fluted disc; 30. a stirring rotating shaft; 31. a stirring rod; 32. a servo motor; 33. a motor shaft; 34. a drive gear; 35. a planetary gear; 36. a fixed gear ring; 37. a vertical screw; 38. vertically moving the block; 39. a temperature detector; 40. a guide block; 41. a vertical guide rod; 42. a drive pulley; 43. a drive belt.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
The embodiment is as follows: referring to fig. 1-8, a drug intermediate reaction kettle for drug production comprises a reaction kettle main body 1, a plurality of feed pipes 2 and a uniform filling mechanism, wherein the uniform filling mechanism is composed of a plurality of quantitative filling components, two vertical support rods 9 are installed at the top of the reaction kettle main body 1, a support cross rod 10 is installed at the top ends of the two vertical support rods 9, a plurality of installation rotating holes are formed in the side part of the support cross rod 10, a driving rotating shaft 11 is installed in each installation rotating hole in a rotating manner, and it needs to be noted that the driving rotating shaft 11 can only rotate but cannot move; one end of each of the plurality of driving rotating shafts 11 is commonly provided with a synchronous rotating unit, and one driving rotating shaft 11 is provided with a fastening unit; the quantitative filling assembly comprises a feeding pipe 4 arranged on the top of the reaction kettle main body 1, a filling cylinder 3 is arranged at the top end of the feeding pipe 4, one end of the feeding pipe 2 is arranged on the side part of the filling cylinder 3, a one-way valve 5 is fixedly arranged on the feeding pipe 2 and the feeding pipe 4, a filling piston 6 matched with the feeding cylinder 3 is sleeved in the filling cylinder 3 in a sliding mode, a connecting moving rod 7 is arranged at the top of the filling piston 6, the top end of the connecting moving rod 7 extends out of the filling cylinder 3 and is provided with a reciprocating moving frame 8, and it needs to be noted that the connecting moving rod 7 can only vertically move up and down and cannot rotate; a driving disc 12 is installed at one end of the driving rotating shaft 11, an eccentric rotating rod 14 is eccentrically installed on the side part of the driving disc 12 through an adaptive adjusting unit, and the end part of the eccentric rotating rod 14 penetrates through the reciprocating frame 8; the reaction kettle main body 1 is provided with a rapid stirring mechanism for uniformly mixing the raw materials and a temperature detection mechanism for movably detecting the reaction temperature, and the rapid stirring mechanism is connected with the temperature detection mechanism.
Borrow by above-mentioned structure, when making a plurality of drive pivot 11 synchronous rotations through synchronous rotation unit, drive pivot 11 rotates and can pass through drive disc 12, adaptation adjusting unit drives eccentric bull stick 14 circumference and rotates, eccentric bull stick 14 circumference rotates and can drive reciprocal frame 8 up-and-down reciprocating motion that moves, and then the accessible is connected and is moved pole 7 and drive filling piston 6 and slide from top to bottom in filling section of thick bamboo 3, at this moment, under the combined action of inlet pipe 2, filling tube 4 and check valve 5, can add the raw materials to the equivalent in reation kettle main part 1, thereby realized once only accomplishing the purpose of getting the interpolation to multiple raw materials, time saving and labor saving has improved production efficiency, and can effectively reduce the condition that influences the medicine midbody quality because of careless mistake of getting, the practicality is good.
As a preferred embodiment of the present embodiment, the synchronous rotating unit includes a plurality of driving worm gears 15 respectively installed on the end portions of the plurality of driving rotating shafts 11, fixed rods are installed on the side portions of the two vertical supporting rods 9, limited bearings 16 are installed on the end portions of the two fixed rods, a control rotating rod 17 is installed in the two limited bearings 16 in a sleeved manner, a plurality of driving worms 18 are installed on the control rotating rod 17 in a sleeved manner, the plurality of driving worms 18 are respectively engaged with the plurality of driving worm gears 15, and a control knob 19 is installed at one end of the control rotating rod 17. The advantage of setting up like this is, when rotating control knob 19, can drive transmission worm 18 through control bull stick 17, and transmission worm 18 rotates can drive pivot 11 through transmission worm wheel 15 and rotate to realized can making the synchronous pivoted purpose of a plurality of drive pivots 11.
As a preferred embodiment of this embodiment, the fastening unit includes a fastening bolt 20 disposed on the support rail 10, a fastening screw hole communicated with one of the mounting rotating holes is formed at the top of the support rail 10, the fastening bolt 20 is threadedly mounted in the fastening screw hole, and the bottom end of the fastening bolt 20 is attached to one of the driving rotating shafts 11. The benefit that sets up like this is, when rotating fastening bolt 20, under the effect of fastening screw, fastening bolt 20 can take place to remove, and then can fix or loosen drive pivot 11, effectively reduces to appear adding the circumstances of accomplishing the back and taking place to continue to add the raw materials to reation kettle main part 1 because of touch control knob 19 carelessly, and stability is good during the use.
As a preferred implementation manner of the present embodiment, the adaptive adjusting unit includes a strip-shaped chute formed on the side portion of the driving disc 12, an adjusting screw 21 is rotatably mounted on the inner wall of the bottom of the strip-shaped chute, and an adjusting moving block 13 is screwed onto the adjusting screw 21, where it should be noted that the side portion of the adjusting moving block 13 is attached to the inner wall of the strip-shaped chute and can only move without rotating; the eccentric rotating rod 14 is installed on the side of the adjusting moving block 13, the top end of the adjusting screw 21 extends out of the driving disc 12 and is installed with an adjusting knob 22, and the locking subunit is installed on the adjusting knob 22. The benefit that sets up like this is, when rotating adjust knob 22, can move the piece 13 through the drive of accommodate the lead screw 21 regulation and remove, adjusts and moves the piece 13 and remove the rotation diameter that can change eccentric bull stick 14, and then can change the upper and lower sliding distance of filling piston 6 to can adjust the quantity of interpolation raw materials, make equipment can add the various raw materials of different proportions, improved application scope.
In this embodiment, the locking sub-unit includes a fixing protrusion 23 installed on the outer periphery of the driving disc 12, an insertion rod sliding hole is opened on the side of the fixing protrusion 23, a locking insertion rod 24 is slidably installed in the insertion rod sliding hole, a plurality of locking insertion holes 25 are uniformly opened on the outer periphery of the adjusting knob 22, one end of the locking insertion rod 24 extends into one of the locking insertion holes 25, a handle pulling block 26 is installed on the other end of the locking insertion rod 24, and an elastic pulling element is installed on the handle pulling block 26. The advantage of setting up like this is, when removing handle pull block 26, can change the position relation between locking inserted bar 24 and the locking jack 25, and then can fix or loosen adjust knob 22, effectively reduces because of adjust knob 22 the rotation appears and leads to the condition that the raw materials proportion of adding changes, and is more stable during the use.
In this embodiment, the elastic pull-back element comprises a return tension spring 27 sleeved on the locking plunger 24, and both ends of the return tension spring 27 are respectively mounted on the side portions of the fixing protrusion 23 and the handle pull block 26. The advantage of this setting is that when loosening the handle pull block 26, under the elasticity of the extension spring 27 that resets, make the handle pull block 26 reset automatically, and then can drive the automatic insertion of locking inserted bar 24 in locking jack 25, will adjust knob 22 and fix all the time, it is firm to stabilize.
As a preferred embodiment of this embodiment, the rapid stirring mechanism includes a central sleeve 28 mounted on the inner wall of the top of the reaction kettle main body 1, a rotating fluted disc 29 is rotatably sleeved on the central sleeve 28, a plurality of rotating holes are uniformly formed on the top of the rotating fluted disc 29, a stirring rotating shaft 30 is rotatably mounted in each of the plurality of rotating holes, and both the rotating fluted disc 29 and the stirring rotating shaft 30 can only rotate without moving; evenly install a plurality of puddlers 31 on a plurality of stirring pivot 30, L shape fixed plate is installed at the top of reation kettle main part 1, servo motor 32 is installed to the bottom of L shape fixed plate, motor shaft 33 is installed to servo motor 32's output, motor shaft 33's bottom extends to in reation kettle main part 1 and installs drive gear 34 with rotating fluted disc 29 looks meshing, install removal rotation unit jointly on a plurality of stirring pivot 30, motor shaft 33 is connected with temperature-detecting mechanism. The advantage of this setting is that when servo motor 32 is started, drive gear 34 will be driven to rotate through motor shaft 33, and drive gear 34 rotates and drives rotation fluted disc 29 to rotate, and then can drive stirring pivot 30 and puddler 31 to carry out the circumferential motion to the mesh that can stir the hybrid processing to the raw materials has been realized.
In this embodiment, the mobile rotation unit includes a plurality of planetary gears 35 respectively installed on the top ends of the plurality of stirring rotating shafts 30, a plurality of straight rods are uniformly installed on the inner wall of the top of the reaction kettle main body 1, a fixed gear ring 36 is installed at the bottom ends of the plurality of straight rods, and the plurality of planetary gears 35 are all engaged with the fixed gear ring 36. The benefit that sets up like this is, when stirring pivot 30 circumferential motion, also can drive planetary gear 35 circumferential motion together, and at this moment, under the effect of fixed ring gear 36, planetary gear 35 can take place the rotation, and then can make stirring pivot 30 carry out the rotation simultaneously at circumferential motion's in-process, has further improved stirring effect, and is more even during the mixed raw materials.
In this embodiment, temperature-detecting mechanism is including setting up thermodetector 39 in reation kettle main part 1, it changes the hole to have seted up the screw rod on the top inner wall of reation kettle main part 1, the screw rod changes the downthehole rotation and installs vertical screw rod 37, vertical shifting block 38 has been cup jointed to the screw thread on the vertical screw rod 37, install vertical guide arm 41 on the top inner wall of reation kettle main part 1, sliding cup joint has guide block 40 on vertical guide arm 41, vertical shifting block 38 and guide block 40 symmetry are installed on thermodetector 39's periphery side, motor shaft 33 is connected with vertical screw rod 37 through the band pulley drive unit. The benefit that sets up like this is, when vertical screw 37 takes place to rotate, under vertical guide arm 41 and guide block 40's common cooperation, vertical screw 37 rotates and can drive thermodetector 39 through vertical piece 38 that moves and reciprocate, has realized that the reaction temperature that can be to in the reation kettle main part 1 moves the purpose that detects, has improved the precision of testing result to the staff can be better carry out adjustment control to reaction temperature.
In this embodiment, the pulley transmission unit includes two driving pulleys 42 respectively sleeved on the motor shaft 33 and the vertical screw 37, and a driving belt 43 is jointly tensioned and sleeved on the two driving pulleys 42. The advantage of this setting is that when motor shaft 33 rotated, can drive one of them driving pulley 42 and rotate, under the effect of driving belt 43, can drive another driving pulley 42 and vertical screw 37 synchronous rotation, played the transmission effect.
The working principle of the invention is as follows:
when the control knob 19 is rotated, the plurality of driving rotating shafts 11 are driven to synchronously rotate through the control rotating rod 17, the transmission worm 18 and the transmission worm wheel 15, the driving rotating shafts 11 can drive the eccentric rotating rod 14 to circularly rotate through the driving disc 12 and the adjusting moving block 13, the eccentric rotating rod 14 can drive the reciprocating moving frame 8 to vertically reciprocate through circular rotation, and further, the filling piston 6 can be driven to vertically slide in the filling cylinder 3 through the connecting moving rod 7, at the moment, under the combined action of the feeding pipe 2, the feeding pipe 4 and the one-way valve 5, raw materials can be filled into the reaction kettle main body 1 in an equivalent manner, so that the purpose of measuring and adding various raw materials can be fulfilled at one time, time and labor are saved, the production efficiency is improved, the situation that the quality of a medicine intermediate is influenced due to careless measuring and wrong measuring can be effectively reduced, and the practicability is good.
When the handle pulling block 26 is pulled, the locking insertion rod 24 can be driven to move out of the locking insertion hole 25, the adjusting knob 22 is loosened, the adjusting knob 22 can be rotated to drive the adjusting moving block 13 to move through the adjusting screw rod 21, the adjusting moving block 13 can be moved to change the rotating diameter of the eccentric rotating rod 14, the vertical sliding distance of the filling piston 6 can be changed, the quantity of the added raw materials can be adjusted, the equipment can be added with various raw materials in different proportions, the application range is improved, after the adjustment is completed, when the handle pulling block 26 is loosened, the handle pulling block 26 can be automatically reset under the elastic action of the reset tension spring 27, the locking insertion rod 24 can be driven to be automatically inserted into the locking insertion hole 25, the adjusting knob 22 is always fixed, the condition that the raw material adding proportion is changed due to the rotation of the adjusting knob 22 is effectively reduced, and the use is more stable.
When starting servo motor 32, can drive gear 34 through motor shaft 33 and rotate, drive gear 34 rotates and drives rotation fluted disc 29 and rotate, and then can drive stirring pivot 30 and puddler 31 and carry out the circumferential motion, the purpose that can stir the hybrid processing to the raw materials has been realized, and simultaneously, stirring pivot 30 circumferential motion also can drive planetary gear 35 and circumferential motion together, at this moment, under the effect of fixed ring gear 36, planetary gear 35 can take place the rotation, and then can make stirring pivot 30 carry out the rotation simultaneously at the circumferential motion in-process, the stirring effect has further been improved, it is more even when mixing the raw materials.
When motor shaft 33 rotates, can drive vertical screw rod 37 through driving pulley 42 and driving belt 43 and rotate in step, under vertical guide arm 41 and guide block 40's common cooperation, vertical screw rod 37 rotates and can drive thermodetector 39 through vertical piece 38 that moves and reciprocate, realized can moving the purpose that detects to the reaction temperature in reation kettle main part 1, improved the precision of testing result, so that the staff can be better carry out adjustment control to reaction temperature, the practicality is better.
Finally, it should be noted that: although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that modifications may be made to the embodiments or portions thereof without departing from the spirit and scope of the invention.
Claims (10)
1. The utility model provides a medicine midbody reation kettle for drug manufacturing, includes reation kettle main part (1), a plurality of inlet pipe (2) and unified filling mechanism, its characterized in that: the uniform filling mechanism is composed of a plurality of quantitative filling components, two vertical support rods (9) are mounted at the top of the reaction kettle main body (1), a support cross rod (10) is mounted at the top ends of the two vertical support rods (9) together, a plurality of mounting rotating holes are formed in the side portion of the support cross rod (10), driving rotating shafts (11) are rotatably mounted in the mounting rotating holes, a synchronous rotating unit is mounted at one end of each of the driving rotating shafts (11) together, and a fastening unit is mounted on one of the driving rotating shafts (11);
the quantitative filling assembly comprises a filling pipe (4) installed on the top of the reaction kettle main body (1), a filling cylinder (3) is installed on the top end of the filling pipe (4), one end of an inlet pipe (2) is installed on the side portion of the filling cylinder (3), one-way valves (5) are fixedly arranged on the inlet pipe (2) and the filling pipe (4), a filling piston (6) matched with the filling cylinder (3) in a sliding and sleeving mode is arranged in the filling cylinder (3), a connecting moving rod (7) is installed at the top of the filling piston (6), the top end of the connecting moving rod (7) extends to the outside of the filling cylinder (3) and is provided with a reciprocating moving frame (8), a driving disc (12) is installed at one end of a driving rotating shaft (11), an eccentric rotating rod (14) is eccentrically installed on the side portion of the driving disc (12) through an adaptive adjusting unit, and the end portion of the eccentric rotating rod (14) penetrates through the reciprocating moving frame (8);
install on reation kettle main part (1) and be used for carrying out the rapid mixing mechanism of homogeneous mixing and carry out the temperature-detecting mechanism that removes the detection to reaction temperature to the raw materials, rapid mixing mechanism with temperature-detecting mechanism is connected.
2. The pharmaceutical intermediate reaction kettle for pharmaceutical production according to claim 1, wherein: synchronous rotation unit is including installing respectively a plurality of transmission worm wheel (15), two on drive pivot (11) tip the dead lever is all installed to the lateral part of vertical vaulting pole (9), two inject bearing (16), two to all install the tip of dead lever the common cup joint in inject bearing (16) and install control bull stick (17), it installs a plurality of transmission worm (18), a plurality of to cup joint on control bull stick (17) transmission worm (18) respectively with a plurality of transmission worm wheel (15) mesh mutually, control knob (19) are installed to the one end of control bull stick (17).
3. The pharmaceutical intermediate reaction kettle for pharmaceutical production according to claim 1, wherein: the fastening unit comprises fastening bolts (20) arranged on the supporting cross rod (10), fastening screw holes communicated with the mounting rotating holes are formed in the top of the supporting cross rod (10), the fastening bolts (20) are installed in the fastening screw holes in a threaded mode, and the bottom ends of the fastening bolts (20) are attached to the driving rotating shafts (11).
4. The pharmaceutical intermediate reaction kettle for pharmaceutical production according to claim 1, wherein: adaptation regulating unit is including seting up bar spout on drive disc (12) lateral part, rotate on the bottom inner wall of bar spout and install accommodate the lead screw (21), accommodate the lead screw (21) are gone up the screw and have been cup jointed the regulation and move piece (13), install eccentric bull stick (14) adjust on the lateral part that moves piece (13), the top of accommodate the lead screw (21) extends to drive disc (12) is outer and install adjust knob (22), install the locking subunit on adjust knob (22).
5. The pharmaceutical intermediate reaction kettle for pharmaceutical production according to claim 4, wherein: the locking subunit comprises a fixing lug (23) installed on the outer peripheral side of the driving disc (12), an insertion rod sliding hole is formed in the side portion of the fixing lug (23), a locking insertion rod (24) is installed in the insertion rod sliding hole in a sliding mode, a plurality of locking insertion holes (25) are evenly formed in the outer peripheral side of the adjusting knob (22), one end of the locking insertion rod (24) extends into one of the locking insertion holes (25), a handle pulling block (26) is installed at the other end of the locking insertion rod (24), and an elastic pulling element is installed on the handle pulling block (26).
6. The pharmaceutical intermediate reaction kettle for pharmaceutical production according to claim 5, wherein: the elastic pull-back element comprises a reset tension spring (27) sleeved on the locking insertion rod (24), and two ends of the reset tension spring (27) are respectively installed on the fixed lug (23) and the side portion of the handle pull block (26).
7. The pharmaceutical intermediate reaction kettle for pharmaceutical production according to claim 1, wherein: quick stirring mechanism is including installing central sleeve (28) on reation kettle main part (1) top inner wall, it has cup jointed rotation fluted disc (29) to rotate on central sleeve (28), a plurality of rotation holes have evenly been seted up at the top of rotation fluted disc (29), and are a plurality of rotate downthehole all rotation and install stirring pivot (30), and are a plurality of evenly install a plurality of puddlers (31) in stirring pivot (30), L shape fixed plate is installed at the top of reation kettle main part (1), servo motor (32) are installed to the bottom of L shape fixed plate, motor shaft (33) are installed to the output of servo motor (32), the bottom of motor shaft (33) extends to in reation kettle main part (1) and install with rotate drive gear (34) that fluted disc (29) meshed mutually, it is a plurality of install removal rotation unit jointly in stirring pivot (30), motor shaft (33) with temperature-detecting mechanism is connected.
8. The pharmaceutical intermediate reaction kettle for pharmaceutical production according to claim 7, wherein: the movable rotation unit comprises a plurality of planetary gears (35) which are respectively installed on the top ends of the stirring rotating shafts (30), a plurality of straight rods are evenly installed on the inner wall of the top of the reaction kettle main body (1), a fixed gear ring (36) is installed at the bottom ends of the straight rods, and the planetary gears (35) are all meshed with the fixed gear ring (36).
9. The pharmaceutical intermediate reaction kettle for pharmaceutical production according to claim 7, wherein: temperature-detecting mechanism is including setting up thermodetector (39) in reation kettle main part (1), it changes the hole to have seted up the screw rod on the top inner wall of reation kettle main part (1), vertical screw rod (37) are installed to the screw rod commentaries on classics downthehole internal rotation, vertical screw rod (37) are gone up the screw thread and have been cup jointed vertical shifting block (38), install vertical guide arm (41) on the top inner wall of reation kettle main part (1), sliding cup jointed guide block (40) on vertical guide arm (41), vertical shifting block (38) with guide block (40) symmetry is installed on the periphery side of thermodetector (39), motor shaft (33) through the pulley drive unit with vertical screw rod (37) are connected.
10. The pharmaceutical intermediate reaction kettle for pharmaceutical production according to claim 9, wherein: the belt wheel transmission unit comprises two transmission belt wheels (42) which are respectively installed on the motor rotating shaft (33) and the vertical screw rod (37) in a sleeved mode, and a transmission belt (43) is jointly tensioned and sleeved on the two transmission belt wheels (42).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210867488.2A CN115350667A (en) | 2022-07-21 | 2022-07-21 | Medicine midbody reation kettle for pharmaceutical production |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210867488.2A CN115350667A (en) | 2022-07-21 | 2022-07-21 | Medicine midbody reation kettle for pharmaceutical production |
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| CN115350667A true CN115350667A (en) | 2022-11-18 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN202210867488.2A Pending CN115350667A (en) | 2022-07-21 | 2022-07-21 | Medicine midbody reation kettle for pharmaceutical production |
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Cited By (1)
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| CN116078334A (en) * | 2023-04-10 | 2023-05-09 | 山东冠森高分子材料科技股份有限公司 | Paranitrophenol sodium apparatus for producing with automatic temperature control function |
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