CN115317739A - Expectoration starts opportunity and judges device and expectoration machine - Google Patents
Expectoration starts opportunity and judges device and expectoration machine Download PDFInfo
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- 206010036790 Productive cough Diseases 0.000 title claims abstract description 186
- 208000024794 sputum Diseases 0.000 claims abstract description 62
- 210000003802 sputum Anatomy 0.000 claims abstract description 60
- 230000002776 aggregation Effects 0.000 claims abstract description 27
- 238000004220 aggregation Methods 0.000 claims abstract description 27
- 238000001914 filtration Methods 0.000 claims abstract description 10
- 238000009825 accumulation Methods 0.000 claims abstract description 7
- 238000011282 treatment Methods 0.000 claims description 17
- 238000000605 extraction Methods 0.000 claims description 6
- 230000004913 activation Effects 0.000 claims 3
- 239000003172 expectorant agent Substances 0.000 claims 1
- 230000003419 expectorant effect Effects 0.000 claims 1
- 230000029058 respiratory gaseous exchange Effects 0.000 description 21
- 238000009423 ventilation Methods 0.000 description 11
- 230000028327 secretion Effects 0.000 description 9
- 238000010586 diagram Methods 0.000 description 6
- 230000000694 effects Effects 0.000 description 6
- 206010011224 Cough Diseases 0.000 description 4
- 230000000875 corresponding effect Effects 0.000 description 4
- 230000010355 oscillation Effects 0.000 description 4
- 230000007423 decrease Effects 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- 230000003434 inspiratory effect Effects 0.000 description 3
- 230000001360 synchronised effect Effects 0.000 description 3
- 230000002596 correlated effect Effects 0.000 description 2
- 230000000977 initiatory effect Effects 0.000 description 2
- 210000004072 lung Anatomy 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
- 230000007246 mechanism Effects 0.000 description 2
- 210000005077 saccule Anatomy 0.000 description 2
- 210000003437 trachea Anatomy 0.000 description 2
- 208000014181 Bronchial disease Diseases 0.000 description 1
- 208000032376 Lung infection Diseases 0.000 description 1
- 206010044565 Tremor Diseases 0.000 description 1
- 230000001133 acceleration Effects 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 238000004364 calculation method Methods 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 230000007012 clinical effect Effects 0.000 description 1
- 230000001276 controlling effect Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000012279 drainage procedure Methods 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 230000000420 mucociliary effect Effects 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
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- 238000011084 recovery Methods 0.000 description 1
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- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B7/00—Instruments for auscultation
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/71—Suction drainage systems
- A61M1/74—Suction control
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2230/00—Measuring parameters of the user
- A61M2230/40—Respiratory characteristics
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Abstract
The invention provides a device for judging the starting time of expectoration, which comprises: the expiratory flow collecting unit is used for collecting negative expiratory flow information in the air passage; a first filter for filtering the negative expiratory flow information to obtain an average flow in the expiration; the second filter is used for filtering the negative expiratory flow information and obtaining high-frequency jitter information in the expiration; the sputum aggregation characteristic variable extracting unit calculates a sputum aggregation characteristic variable according to the average flow and the high-frequency shaking information, wherein the sputum aggregation characteristic variable is in negative correlation with the average flow and in positive correlation with the high-frequency shaking information; and the expectoration starting time judging unit is used for informing the starting of expectoration operation when judging that the sputum aggregation characteristic variable is larger than a set threshold value. The invention also provides a expectoration machine. The device can automatically judge the accumulation of sputum in the airway and automatically start a expectoration drainage program according to the accumulation degree of the sputum in the airway.
Description
Technical Field
The invention relates to the technical field of airway treatment, in particular to a expectoration starting time judgment device and an expectoration machine.
Background
The normal people mainly remove secretions in airways by two mechanisms of airway mucociliary movement and cough, but for intubated patients (namely invasive ventilation patients) depending on breathing machine support, the two airway secretion mechanisms of the patients are weakened to different degrees, and the patients are generally accompanied by primary airway diseases (such as lung infection and chronic bronchial diseases) causing the increase of airway secretions (compared with the normal people), so that airway secretion management is particularly important for the patients with invasive ventilation. The conventional airway secretion management technology is mainly endotracheal sputum aspiration, and the conventional technology is very easy to cause many complications such as patient discomfort, blood oxygen decline and the like.
Patent CN105343944 proposes an online airway drainage device capable of working with a breathing machine for simulating cough, which is also called a synchronous expectoration machine. The device utilizes a tee bend constitutional component to connect breathing machine, negative pressure suction device (synchronous expectoration machine promptly), patient, and under normal condition, the passageway between patient and the negative pressure suction device is in the off-state, does not influence the breathing machine and implements normal ventilation to the patient. Once the airway sputum drainage program is started, the negative pressure suction device judges the opportunity (the rapid decline of the inspiration peak value) of the ventilator switched from the inspiration phase to the expiration phase by using the sensor on the three-way structure, and then cuts off the normal ventilation channel of the ventilator and a patient by using the saccule valve on the three-way structure at the moment when the moment of judging the opportunity of switching arrives, and simultaneously, rapidly opens the negative pressure suction channel to carry out negative pressure suction on the patient; after the negative pressure suction lasts for a short time, the system automatically restores the normal ventilation connection between the respirator and the airway of the patient, and the respirator inflates the patient. So, breathing machine and negative pressure suction device cooperate repeatedly, and the breathing machine is implemented to the patient and is aerifyd, and negative pressure suction device implements to bleed to the patient to reach the drainage effect that a simulation nature people coughed. The on-line drainage technology can avoid a plurality of complications caused by the traditional endotracheal sputum suction, and realize the effect of non-invasively removing the sputum of the trachea of the intubated patient.
Present and the system that online air flue sputum drainage was realized to the cooperation of breathing machine, synchronous expectoration machine system promptly to a set of expectoration drainage procedure of mode start-up of timing, the patient normally has a rest if expectoration drainage is too frequent, and the therapeutic value of this system can not be embodied to expectoration drainage untimely. That is, the user (airway manager or respiratory therapist) is required to set a fixed expectoration start interval, which may be set to 15 minutes to 120 minutes in general. After the expectoration machine system waits for a set time interval to arrive, a group of expectoration drainage treatment can be started no matter whether sputum is accumulated in the airway of a patient or not. Such a method and system for starting online expectoration drainage at regular time has obvious defects:
(1) If the expectoration interval is set to be too short, the expectoration drainage can be frequently executed, so that the expectoration drainage is not only redundant, but also disturbs the recovery and normal rest of the patient, frequently interrupts the ventilation treatment program of the breathing machine, and has more or less negative influence on the ventilation effect of the breathing machine (such as possibly frequently triggering the alarm of the breathing machine).
(2) Conversely, if the expectoration interval is set too long, it will cause the drainage of airway sputum to be untimely and will not function as the automatic airway secretion expected by the system.
(3) When the system is applied, the operating user needs to know the airway secretion condition of the patient very carefully, and the expectoration interval is frequently and individually adjusted according to the illness condition and the progress of the illness condition of different patients, so that the operation difficulty of the user is increased, in other words, the value of the system reflects that the dependency on the operation experience of the user is too high.
Disclosure of Invention
In order to overcome the contradiction problem of the existing timing online expectoration drainage system, the invention provides a device for judging the starting time of expectoration, which comprises: the expiratory flow collecting unit is used for collecting negative expiratory flow information in the air passage; a first filter for filtering the negative expiratory flow information to obtain an average flow in the expiration; the second filter is used for filtering the negative expiratory flow information and obtaining high-frequency jitter information in the expiration; the sputum aggregation characteristic variable extraction unit calculates a sputum aggregation characteristic variable according to the average flow and the high-frequency shaking information, wherein the sputum aggregation characteristic variable is in negative correlation with the average flow and in positive correlation with the high-frequency shaking information; and the expectoration starting time judging unit is used for informing the start of expectoration operation when judging that the sputum aggregation characteristic variable is larger than a set threshold value.
According to another aspect of the present invention, there is also provided a expectoration machine having an expectoration start timing determination device, including:
expectoration starts opportunity and judges device includes: the expiratory flow collecting unit is used for collecting negative expiratory flow information in the air passage; a first filter for filtering the negative expiratory flow information to obtain an average flow in the expiration; the second filter is used for filtering the negative expiratory flow information and obtaining high-frequency jitter information in the expiration; the sputum aggregation characteristic variable extraction unit calculates a sputum aggregation characteristic variable according to the average flow and the high-frequency shaking information, wherein the sputum aggregation characteristic variable is in negative correlation with the average flow and in positive correlation with the high-frequency shaking information; a expectoration starting time judging unit which informs starting of expectoration operation when judging that the sputum aggregation characteristic variable is larger than a set threshold;
and the expectoration control device starts a group of expectoration treatment after receiving the notice of the expectoration starting time judging device to start the expectoration operation.
The device of the invention has the advantages that: (1) The device can automatically judge the accumulation of airway sputum and automatically start a expectoration drainage program according to the accumulation degree of the airway sputum, so that the device is more intelligent. (2) The problem that the timing interval is too long or too short in the existing system is solved. (3) The dependence on the use experience of the user is reduced, the use experience of the user can be improved, and the medical value of the online expectoration equipment is maximized.
Drawings
In order that the invention may be more readily understood, it will be described in more detail with reference to specific embodiments thereof that are illustrated in the accompanying drawings. These drawings depict only typical embodiments of the invention and are not therefore to be considered to limit the scope of the invention.
Fig. 1 is a diagram showing an application of the expectoration start timing determination device of the present invention.
Fig. 2 is a schematic operation diagram of expectoration and ventilation.
FIG. 3 is a schematic diagram of one embodiment of the apparatus of the present invention.
Fig. 4 is a flow chart of the operation of the apparatus of the present invention.
Fig. 5 is a flow chart of the device of the present invention applied to a expectoration machine.
Reference numerals
The sputum-expectoration device comprises a 1-three-way saccule valve, a 2-flow sensor, a 3-expectoration pipeline, a 4-measurement and control pipeline, a 5-sputum-collecting cup, a 6-measurement and control joint, a 7-filter, an 8-patient port, a 9-expectoration machine port, a 10-respirator port and an 11-saccule.
Detailed Description
Embodiments of the present invention will be described below with reference to the accompanying drawings so that those skilled in the art can better understand the present invention and can carry out the present invention, but the illustrated embodiments do not limit the present invention, and technical features in the following embodiments and embodiments can be combined with each other without conflict, wherein the same components are denoted by the same reference numerals.
Fig. 1 shows a schematic application diagram of the automatic expectoration timing determination device of the present invention. The integrated expectoration machine can be integrated in the expectoration machine, and can also be used as a separate external module to be combined with the expectoration machine. The expectoration machine is also provided with an expectoration control device which carries out information interaction with the expectoration starting time judging device.
In figure 1 is shown a expectoration machine, a ventilator, connected to a patient by a three-way balloon valve 1. Wherein the patient port of the three-way balloon valve 1 is connected to a patient, the port 9 of the expectoration machine is connected to the expectoration machine through an expectoration pipeline 3, and the port 10 of the breathing machine is connected to the breathing machine through a pipeline. The balloon 11 in the three-way balloon valve 1 has an opening to the atmosphere for deflation and inflation. A flow sensor 2 is provided on the ventilator port 10.
Under the condition of no airway secretion accumulation, the expectoration machine is not started, the three-way balloon valve 1 is in an open state (the balloon 11 is in a deflation state), and the respirator controls the inspiratory airflow and the expiratory airflow of the patient. Once the expectoration treatment is started, in the exhalation phase of the respirator, the three-way balloon valve 1 is in the closed state (the balloon 11 is in the inflated state, and the air path between the patient and the respirator is blocked), and the expectoration machine guides the expiratory airflow of the patient into the expectoration machine by means of negative pressure suction and discharges the expiratory airflow. Because expectoration machine negative pressure suction's effect, patient's expiratory airflow velocity of flow can sharply increase, and the secretion in the air flue can be taken out to expectoration pipeline 3 to the air current of acceleration.
As shown in the operational schematic diagram of expectoration ventilation of fig. 2, when expectoration treatment is not activated, the ventilator is normally ventilated and controls the pressure and flow in the ventilation line. When the pressure is increased during inspiration, the airflow moves towards the airway of the patient (the flow is positive); the pressure decreases (to PEEP) on exhalation and the flow moves towards the ventilator (flow is negative).
After starting a expectoration treatment, the flow of air to the patient is still provided by the ventilator during the inspiratory phase; at the moment when the breathing machine turns from inspiration to expiration, the expectoration machine blocks the breathing machine channel (the balloon 11 is inflated) by controlling the three-way balloon valve 1, a suction valve (not marked in figure 1) in the expectoration machine is opened, the pressure in the air channel is changed into negative pressure, and under the action of the negative pressure (the pressure in the lung of a patient is positive), the air flow moves to the expectoration machine. The negative air flow of expectoration reduces to a certain degree, and expectoration machine closes off inside suction valve earlier, opens three-way sacculus valve 1 on the pipeline again (sacculus valve 11 gassing), and the breathing machine communicates with the patient again, and the breathing machine triggers to breathe in again and is full of patient's lung tolerance, and after breathing machine inhales, expectoration machine restarts the suction (blocks the breathing machine passageway, opens suction channel). The breathing machine controls inspiration, the expectoration machine controls expiration (suction), and the expectoration treatment is regarded as a group of expectoration treatment after repeated times.
After a group of expectoration treatment (the expectoration times are set by a user), the expectoration machine is in a waiting state, and the breathing machine takes over all inhalation and exhalation control.
Currently, an online expectoration machine device on the market, such as CoughSync 100, allows a user to set a start interval of expectoration treatment, and starts the online expectoration treatment in a timed manner.
Fig. 3 shows a schematic structural diagram of the expectoration start timing determination device of the present invention. Fig. 4 shows a flow chart of the operation of the device. The apparatus of the present invention comprises: the sputum collection device comprises an expiratory flow acquisition unit, a first filter, a second filter, a sputum aggregation characteristic variable extraction unit and a starting expectoration judgment unit.
The flow of breathing gas within the airway includes positive flow and negative flow. The positive air flow is inspiratory air flow, and the negative air flow is expiratory air flow. The expiratory flow acquisition unit (via the flow sensor 2) only acquires negative expiratory flow information in the airway.
The collected expiratory flow is passed through two filters, the first filter is used to obtain the average flow in the expiration, and the filtered information is denoted by LP _ Qe (t). The second filter is used to obtain high frequency jitter information, and the filtered information is represented by HP _ Qe (t), where t represents time. The first filter may be a low pass filter and the second filter may be a high pass filter.
The low pass filtered LP _ Qe (t) is used to calculate the Average flow in exhalation Average _ LP _ Qe, which is calculated as follows:
the high-pass filtered HP _ Qe (t) is used to calculate the jitter Power _ HP _ Qe of the high-frequency signal, and the calculation formula is as follows:
te in the formula represents the expiration time, i.e., the time during which the flow rate per breath is negative.
And calculating the sputum aggregation characteristics through the sputum aggregation characteristic variable extraction unit, and judging whether sputum is aggregated. The sputum aggregation characteristic variable is negatively correlated with the Average flow Average _ LP _ Qe and positively correlated with the jitter Power _ HP _ Qe. When sputum is gathered in the large airway to a certain degree, the expiratory airway resistance of a patient is inevitably increased, so that the Average expiratory flow is reduced, the Average flow Average _ LP _ Qe is reduced, and the characteristic variable corresponding to the increase of the air resistance is increased. After the sputum gathers to a certain degree, will arouse the oscillation of expiratory airflow (as shown in fig. 2), the more the sputum, the oscillation intensity is big more, and it is also can increase to tremble Power _ HP _ Qe, and the corresponding characteristic variable of sputum gathering also can increase.
In one embodiment, the characteristic variable Sputum _ Index (Sputum indicator variable) characterizing whether the airway has Sputum accumulated after each breath is calculated according to the following equation (3):
Sputum_Index(T)＝Power_HP_Qe(T)/Average_LP_Qe(T) (3)
t in the formula represents a breath.
When sputum is gathered in the large airway to a certain degree, the expiratory airway resistance of a patient is inevitably increased, so that the Average expiratory flow is reduced, and the characteristic variable corresponding to the increase of the air resistance is increased because the Average _ LP _ Qe is in the denominator term of the formula (3); moreover, after the sputum is gathered to a certain degree, the oscillation of expiratory airflow (as shown in fig. 2) is triggered, the more the sputum is, the greater the oscillation intensity is, that is, power _ HP _ Qe is increased, and as the airflow jitter Power is in the molecular term of formula (3), the corresponding characteristic variable of sputum gathering is also increased.
The expectoration start timing judgment unit judges that when the characteristic variable indicating the degree of Sputum aggregation is greater than a certain set Threshold (represented by Cough _ Initiation _ Threshold), namely, sputum _ Index (T) > Cough _ Initiation _ Threshold, the expectoration start timing judgment module notifies the expectoration control device to start a set of expectoration treatments.
As shown in fig. 5, the expectoration control device is in a waiting stage during ventilation of the normal ventilator, the set of expectoration control is not started until receiving the expectoration starting instruction sent by the expectoration starting judgment device, and after the set of expectoration treatment is finished, the expectoration control device can wait for the expectoration starting judgment device to detect the effect of the set of expectoration treatment again. Expectoration starts judgement device if judges this expectoration treatment has reduced air flue sputum gathering characteristic variable, then thinks expectoration is effective, if judges that air flue sputum gathering characteristic variable does not reduce or rise on the contrary, then can think expectoration is invalid. Under the invalid condition of expectoration, expectoration machine sends the warning to the suggestion user pays close attention to patient's air flue sputum gathering serious incident, and the user can respond this warning and implement operations such as manual trachea sputum aspiration for the patient.
After the automatic expectoration starting and judging device is applied, the timing starting expectoration function of the system of the original expectoration machine can still exist as a backup, and a longer backup timing interval can be set, so that the clinical effect that the treatment effect is not reduced and the patient is not disturbed too much can be achieved, and the use and setting difficulty of an operator of the expectoration machine is also reduced.
The embodiments described above are merely preferred specific embodiments of the present invention, and the present specification uses the phrases "in one embodiment," "in another embodiment," "in yet another embodiment," or "in other embodiments," which may each refer to one or more of the same or different embodiments in accordance with the present disclosure. General changes and substitutions by those skilled in the art within the technical scope of the present invention should be included in the protection scope of the present invention.
Claims (10)
1. A expectoration start timing judgment device characterized by comprising:
the expiratory flow collecting unit is used for collecting negative expiratory flow information in the air passage;
a first filter for filtering the negative expiratory flow information to obtain an average flow in the expiration;
the second filter is used for filtering the negative expiratory flow information and obtaining high-frequency jitter information in the expiration;
the sputum aggregation characteristic variable extraction unit calculates a sputum aggregation characteristic variable according to the average flow and the high-frequency shaking information, wherein the sputum aggregation characteristic variable is in negative correlation with the average flow and in positive correlation with the high-frequency shaking information;
and the expectoration starting time judging unit is used for informing the start of expectoration operation when judging that the sputum aggregation characteristic variable is larger than a set threshold value.
2. The expectoration activation timing determination device according to claim 1,
the first filter is a low-pass filter and the second filter is a high-pass filter.
3. The expectoration activation timing determination device according to claim 1, wherein the average flow rate in the exhalation is obtained by the following equation:
average _ LP _ Qe represents the Average flow in exhalation, and LP _ Qe (t) represents the variable filtered by the first filter.
4. The expectoration activation timing determination apparatus according to claim 3, wherein the jitter information of the high frequency signal is obtained by the following equation:
power _ HP _ Qe represents the jitter Power of the high frequency signal, and HP _ Qe (t) represents the variable filtered by the second filter.
5. The expectoration start timing judgment device according to claim 4, wherein the sputum accumulation characteristic variable after each breath is calculated according to the following formula:
Sputum_Index(T)＝Power_HP_Qe(T)/Average_LP_Qe(T)
sputum _ Index represents a Sputum aggregation characteristic variable, and T represents a breath.
6. A expectoration machine, characterized by comprising:
expectoration starts opportunity and judges device includes: the expiratory flow collecting unit is used for collecting negative expiratory flow information in the air passage; a first filter for filtering the negative expiratory flow information to obtain an average flow in the expiration; the second filter is used for filtering the negative expiratory flow information and obtaining high-frequency jitter information in the expiration; the sputum aggregation characteristic variable extraction unit calculates a sputum aggregation characteristic variable according to the average flow and the high-frequency shaking information, wherein the sputum aggregation characteristic variable is in negative correlation with the average flow and in positive correlation with the high-frequency shaking information; a expectoration starting time judging unit which informs starting of expectoration operation when judging that the sputum aggregation characteristic variable is larger than a set threshold;
and the expectoration control device starts a group of expectoration treatment after receiving the notice of the expectoration starting time judging device to start the expectoration operation.
7. The expectoration machine of claim 6,
the first filter is a low-pass filter and the second filter is a high-pass filter.
8. A expectoration machine according to claim 7, wherein the average flow in exhalation is obtained by the following equation:
average _ LP _ Qe represents the Average flow in exhalation, and LP _ Qe (t) represents the variable filtered by the first filter.
9. The expectorant machine of claim 8, wherein the dithering information of the high frequency signal is obtained by the following formula:
power _ HP _ Qe represents the jitter Power of the high frequency signal, and HP _ Qe (t) represents the variable filtered by the second filter.
10. The expectoration machine of claim 9, wherein the sputum accumulation characteristic variable after each breath is calculated according to the following formula:
Sputum_Index(T)＝Power_HP_Qe(T)/Average_LP_Qe(T)
sputum _ Index represents a Sputum aggregation characteristic variable, and T represents a breath.
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| US20080110461A1 (en) * | 2004-10-20 | 2008-05-15 | Resmed Limited | Method and Apparatus For Detecting Ineffective Inspiratory Efforts and Improving Patient-Ventilator Interaction |
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| CN215504938U (en) * | 2021-04-15 | 2022-01-14 | 深圳市安保科技有限公司 | Novel breathing machine with sputum excretion function |
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2022
- 2022-08-15 CN CN202210973880.5A patent/CN115317739A/en active Pending
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20080110461A1 (en) * | 2004-10-20 | 2008-05-15 | Resmed Limited | Method and Apparatus For Detecting Ineffective Inspiratory Efforts and Improving Patient-Ventilator Interaction |
| CN105031784A (en) * | 2014-04-30 | 2015-11-11 | 张焕祯 | Alarm method of respirator and alarm system of respirator |
| US20200261674A1 (en) * | 2017-11-09 | 2020-08-20 | Autonomous Healthcare, Inc. | Clinical Decision Support System for Patient-Ventilator Asynchrony Detection and Management |
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