CN115305178B - Integrated form nucleic acid pharynx swab sampling tube that singly adopts - Google Patents
Integrated form nucleic acid pharynx swab sampling tube that singly adopts Download PDFInfo
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- CN115305178B CN115305178B CN202210979166.7A CN202210979166A CN115305178B CN 115305178 B CN115305178 B CN 115305178B CN 202210979166 A CN202210979166 A CN 202210979166A CN 115305178 B CN115305178 B CN 115305178B
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
- A61B10/0045—Devices for taking samples of body liquids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
- A61B10/0045—Devices for taking samples of body liquids
- A61B10/0051—Devices for taking samples of body liquids for taking saliva or sputum samples
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
- B01L3/5082—Test tubes per se
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- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Sampling And Sample Adjustment (AREA)
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Abstract
The invention provides an integrated nucleic acid throat swab single-sampling tube, which consists of a cylindrical nucleic acid sampling tube and a throat swab. The sampling tube bottom is equipped with the tube bottom hole, and the upper shed is equipped with the lid, is equipped with the liquid bag in the lid, and the mouth of pipe is equipped with the infusion thorn awl, has the U-shaped supporting disk in the pipe, and U-shaped supporting disk bottom has big-end-up's round platform shape hole. The pharynx swab stick passes the sampling pipe, has the neck of round platform shape on the pharynx swab stick, and the pharynx swab stick divide into two sections from top to bottom, is equipped with connecting portion between two sections, and the fixed cylinder stopper that has the semicircular handle that has of lower extreme of pharynx swab stick. The sampling tube has extremely smooth sampling action and high sampling speed.
Description
Technical Field
The invention belongs to a medical article, and relates to a disposable single-detection nucleic acid sampling tool.
Background
The current technical background is as follows: the cotton swabs are various in types, including dust-free wiping sticks, clean cotton swabs and medical cotton swabs, and the cotton swabs are coated immediately. The dust-free wiping rod is essentially different from a cotton swab, the cotton swab head is made of cotton, dust-free washing treatment cannot be carried out, and scraps are likely to be scraped and fall off in the wiping process. The material of the head of the dust-free wiping rod is divided into a sponge head and a cloth head, the sponge head and the cloth head are subjected to dust-free treatment and are purified and packaged in a dust-free room, so that the used wiping material is bound to reach more than one hundred grades in a high-grade dust-free environment, only the wiping cloth and the wiping rod can meet the requirements, and the wiping paper and the cotton swab can be only used for wiping products in a common environment. The clean swab is the only choice for accurate clean wiping applications, eliminates contaminants and remains clean in the particular environment of the manufacturing process, and has low chemical residue content after wiping. The throat swab material mainly comprises a nylon short fiber fluff head and a medical ABS plastic rod. The nylon staple acts like a soft brush, effectively improves the collection of cell material, and is easy to elute. The structure of a common nucleic acid sampling tube comprises a test tube with one closed end, the other end of the test tube is provided with a cover capable of sealing the test tube, and preservation solution is filled in the test tube. The method for sampling the virus comprises the following steps: open the test tube lid earlier, keep the test tube mouth of pipe perpendicularly upwards to pour out in case the preservative solution, get a pharynx swab, after cleaning by the pharyngeal portion of sampling personnel, insert the test tube with the pharynx swab, break off the pharynx swab stick off with the fingers and thumb, make pharynx swab nylon short-staple fine hair head fall into the test tube, cover the test tube lid, sealed test tube, this lid has the internal thread, applys positive pressure through the screw thread to the mouth of pipe and realizes static seal. The sampling mode has the disadvantages that the sampling action is too much, the liquid in the test tube needs to be carefully kept not to overflow during sampling, the sample is easily polluted, the action force always needs to be kept right during sampling, and a sampler reflects the operation action of screwing the thread and is very troublesome and time-consuming in the sampling process, so the sampling speed is low, and the efficiency is low.
Disclosure of Invention
In order to solve the problems of too many sampling actions and low sampling speed of the existing virus sampling mode at one time, the invention provides an integrated nucleic acid throat swab single-sampling tube, which integrates a throat swab, a preservation solution and a sampling tube together, simplifies the actions during virus sampling and greatly improves the virus sampling speed.
The invention discloses an integrated nucleic acid throat swab single-sampling tube, which adopts the technical scheme that: the lower end of the cylindrical nucleic acid sampling tube is provided with a tube bottom, the center of the tube bottom is provided with a tube bottom hole, the nucleic acid sampling tube is internally provided with a U-shaped supporting plate, the sampling tube is divided into an upper section and a lower section by the U-shaped supporting plate, the distance between the U-shaped supporting plate and the lower bottom of the nucleic acid sampling tube is one third of the height of the nucleic acid sampling tube, and the bottom of the U-shaped supporting plate is provided with a circular truncated cone-shaped hole with a large upper part and a small lower part. The pharynx swab is divided into an upper section and a lower section, a connecting part is arranged between the upper section and the lower section, and the diameter of the connecting part is slightly smaller than that of the pharynx swab rod, so that the pharynx swab is only broken at the connecting part when the pharynx swab is intentionally broken; the upper end of pharynx swab is nylon short-staple fine hair head, nylon short-staple fine hair head's below tightly links a neck that big-end-up has certain elastic round platform shape, round platform shape neck top is thickest end, the below is thinnest end, nylon short-staple fine hair head is pressed close to round platform shape neck thickest end, the diameter of thinnest end equals the diameter of pharynx swab stick, the neck of this round platform shape just in time can fill in the round platform shape hole of U-shaped supporting disk bottom, require to fill in tightly and realize the friction auto-lock of mechanism, sealed upper segment sampling tube, separate into upper and lower two spaces to the sampling tube. The bottom of the pharynx swab stick is provided with a cylindrical plug, the cylindrical plug can be just plugged into a tube bottom hole at the bottom of the sampling tube, so that the sampling tube and the pharynx swab can be temporarily fixed together, the lower end of the cylindrical plug is provided with a semi-annular handle, and the sampling tube can be held or the semi-annular handle can be held for sampling. The sampling pipe mouth of pipe is equipped with the sampling pipe lid, this lid adopts integral plastics hinge and sampling pipe to be connected, the position that corresponds the oral area of sampling pipe in the lid is equipped with the sealing washer, adopt conventional technique to apply the static seal mode of positive pressure and seal and the auto-lock, be equipped with the safety lock on the lid of sampling pipe, the safety lock can turn over down and buckle on the buckle of sampling pipe, the sampling pipe lid is hollow cylinder, be equipped with the liquid bag in the lid, the lid is close to the orificial one side of sampling pipe and is equipped with the taper hole, the liquid bag can be pricked through this awl hole to the thorn awl. The upper opening of the sampling tube and the corresponding position of the through-cone hole are provided with the pricker, the pricker can prick the liquid sac while the cover is covered, the preservation liquid is discharged, the height of the pricker tip is flush with the upper opening of the sampling tube and does not need to be higher than the upper opening of the sampling tube so as to prevent the pricker from hurting people, the bottom in the sealing ring of the cover of the sampling tube protrudes out of the sealing ring, so that the liquid sac in the cover of the sampling tube is higher than the sealing ring, and after the cover is covered, the opening part of the sampling tube is tightly attached to the sealing ring, so that the pricker can prick the liquid sac; the height of the bottom protrusion in the sealing ring of the sampling tube cover is 3-5 mm, the height can not only puncture the liquid bag, but also does not influence the closing of the cover, and a transfusion hole is arranged in the puncture cone and can guide liquid out of the liquid bag.
Insert the sampling pipe with the pharynx swab from the last mouth of sampling pipe, after the round platform shape hole of the bottom of U-shaped supporting disk is passed, wear out from the pipe bottom hole, the cylinder stopper that has the semi-annular handle on the lower extreme of pharynx swab is fixed, the cylinder stopper is filled into the pipe bottom hole, the position such as the oronasal of the person of being sampled can not contact the lid of sampling pipe when the length of pharynx swab stick will satisfy the sampling, after the sampling is accomplished, take out the pharynx swab downwards, draw into the round platform shape hole of the bottom of U-shaped supporting disk to the neck of the round platform shape of pharynx swab stick, seal, at this moment, the connecting portion of pharynx swab upper and lower two sections are just in time stayed the pipe bottom hole of sampling pipe, break off the pharynx swab stick with the fingers and thumb after, will make remaining pharynx swab stick can not spill the pipe bottom, consequently, the intensity of connecting portion will satisfy under the above-mentioned condition just in time can break off with the fingers and thumb at connecting portion, the intensity of this connecting portion still can not break from here when satisfying normal nucleic acid sampling still simultaneously. The cap can be covered after the throat swab rod is broken off, the safety buckle is buckled after the cap is covered, double safety is achieved, the puncture cone can puncture the liquid sac when the cap is sealed, the preservation liquid flows into the sampling tube, and the throat swab nylon short fiber fluff head is soaked in the preservation liquid.
The invention has the beneficial effects that: the integrated nucleic acid throat swab single sampling tube has a simple structure, simplifies nucleic acid sampling actions to the maximum extent, and ensures that the sampling actions are extremely smooth after sampling, namely, one sampling action, one breaking action and one covering action without considering the action accuracy and excessive attention to action force, thereby improving the sampling speed to the maximum extent.
Drawings
The invention is further described below with reference to the accompanying drawings.
FIG. 1 is a schematic of the present invention.
In fig. 1, nylon short fiber fluff heads, 2, truncated cone-shaped necks, 3, connecting parts, 4, safety fasteners, 5, covers, 6, liquid bags, 7, sealing rings, 8, cone passing holes, 9, stabbing cones, 10, buckles, 11, U-shaped supporting plates, 12, truncated cone-shaped holes, 13, tube bottoms, 14, tube bottom holes, 15, throat swabs, 16, cylindrical plugs, 17 and a semi-annular handle.
Detailed Description
The upper opening of the cylindrical nucleic acid sampling tube is provided with a cover 5, the lower end of the cylindrical nucleic acid sampling tube is provided with a tube bottom 13, the middle of the tube bottom is provided with a tube bottom hole 14, the nucleic acid sampling tube is internally provided with a U-shaped supporting plate 11 which divides the sampling tube into an upper section and a lower section, the distance between the U-shaped supporting plate and the lower bottom of the nucleic acid sampling tube is one third of the height of the nucleic acid sampling tube, and the bottom of the U-shaped supporting plate is provided with a circular truncated cone shaped hole 12 with a larger upper part and a smaller lower part. The pharynx swab 15 is divided into an upper section and a lower section, the connecting part 3 is arranged between the upper section and the lower section, and the diameter of the connecting part is slightly smaller than that of the pharynx swab, so that the pharynx swab is conveniently broken only at the position when the pharynx swab is broken intentionally; the upper end of pharynx swab is nylon short-staple fine hair head 1, nylon short-staple fine hair head's the following closely link one and go up big-end-down and have the neck 2 of certain elastic round platform shape, round platform shape neck top is thickest end, the below is thinnest end, nylon short-staple fine hair head 1 is pressed close to round platform shape neck thickest end, the diameter of thinnest end equals the diameter of pharynx swab stick, the neck of this round platform shape just in time can fill in the round platform shape of U-shaped supporting disk bottom downthehole, require to fill in tightly and realize the friction auto-lock of mechanism, and sealed upper segment sampling tube, separate into upper and lower two spaces with the sampling tube. The lower end of the pharynx swab is provided with a cylindrical plug 16 which can be plugged into a tube bottom hole 14 at the tube bottom of the sampling tube, so that the sampling tube and the pharynx swab can be temporarily fixed together, and the lower end of the cylindrical plug is provided with a semi-annular handle 17 which can be used for holding the sampling tube or pinching the semi-annular handle for sampling. The sampling pipe mouth of pipe is equipped with the sampling pipe lid, this lid adopts integral plastics hinge and sampling pipe to be connected, the position that corresponds the oral area of sampling pipe in the lid is equipped with sealing washer 7, adopt conventional technique to apply the quiet sealed mode of normal pressure and seal and the auto-lock, be equipped with safety catch 4 on the lid of sampling pipe, safety catch can turn over down buckle on buckle 10 on the sampling pipe, the sampling pipe lid is hollow cylinder, be equipped with liquid bag 6 in the lid, the lid is close to the orificial one side of sampling pipe and is equipped with taper hole 8, the thorn awl can prick the liquid bag through this awl hole of crossing. The upper opening of the sampling tube is provided with a pricker 9 corresponding to the through-cone hole, the pricker can prick the liquid sac to discharge preservation liquid while the cover is covered, the height of the pricker is flush with the upper opening of the sampling tube and does not exceed the upper opening of the sampling tube to prevent the pricker from hurting people, the bottom in the sealing ring of the cover of the sampling tube protrudes out of the sealing ring, so that the liquid sac in the cover of the sampling tube is higher than the sealing ring, when the cover is covered, the opening of the sampling tube is tightly attached to the sealing ring, and the pricker can prick the liquid sac; the height of the bottom protrusion in the sealing ring of the sampling tube cover is 3-5 mm, the height can not only puncture the liquid bag, but also does not influence the closing of the cover, and a transfusion hole is arranged in the puncture cone and can guide liquid out of the liquid bag.
Inserting a throat swab 15 into a sampling tube from the upper opening of the sampling tube, penetrating the throat swab through a circular truncated cone-shaped hole 12 at the bottom of a U-shaped supporting plate, penetrating the throat swab out of a tube bottom hole 14, fixing a cylindrical plug 17 with a semi-annular handle 16 at the lower end of the throat swab, plugging the cylindrical plug 17 into the tube bottom hole 14, wherein the length of the throat swab rod is required to meet the requirement that parts such as the mouth and the nose of a person to be sampled cannot contact with the sampling tube during sampling, after sampling is completed, drawing the throat swab downwards, drawing a circular truncated cone-shaped neck 2 of the throat swab into the circular truncated cone-shaped hole 12 at the bottom of the U-shaped supporting plate, sealing is carried out, at the moment, a connecting part 3 of the upper section and the lower section of the throat swab is just left at the tube bottom hole 14 of the sampling tube, and after the throat swab rod is broken, the remaining throat swab rod cannot leak out of the tube bottom, so that the connecting part can be just broken under the above condition, and meanwhile, the strength of the connecting part is required to meet the requirement that normal nucleic acid sampling cannot be broken. The cap 5 can be covered after the throat swab stick is broken off, the safety buckle 4 is buckled after the cap is covered, double safety is achieved, the puncture cone 9 can puncture the liquid sac 6 when the cap is sealed, preservation liquid flows into the sampling tube, and the throat swab nylon short fiber fluff head 1 is soaked in the preservation liquid.
Claims (1)
1. The utility model provides an integrated form nucleic acid pharynx swab sampling tube of singly adopting, characterized by: a tube bottom hole is formed in the middle of the tube bottom of a cylindrical nucleic acid sampling tube, a U-shaped supporting plate is arranged inside the sampling tube and divides the sampling tube into an upper section and a lower section, the distance between the U-shaped supporting plate and the lower bottom of the nucleic acid sampling tube is one third of the height of the nucleic acid sampling tube, and a circular truncated cone-shaped hole with a large upper part and a small lower part is formed in the bottom of the U-shaped supporting plate; the mouth of the sampling tube is provided with a sampling tube cover, the cover is connected with the sampling tube by adopting an integral plastic hinge, a sealing ring is arranged in the cover corresponding to the mouth of the sampling tube, the cover of the sampling tube is provided with a safety buckle which can be turned down and buckled on a buckle on the sampling tube, the sampling tube cover is a hollow cylinder, a liquid bag is arranged in the cover, and one side of the cover, which is close to the mouth of the sampling tube, is provided with a through-cone hole; a puncture cone is arranged at the position where the upper opening of the sampling pipe corresponds to the through cone hole, a transfusion hole is arranged in the puncture cone, the height of the puncture cone tip is flush with the upper opening of the sampling pipe, a sealing ring is protruded from the bottom in the sealing ring of the cover of the sampling pipe, and the protruded height is 3-5 mm, so that a liquid bag in the cover of the sampling pipe is higher than the sealing ring; insert the sampling pipe to the pharynx swab stick from the last mouthful of sampling pipe, pass behind the round platform shape hole of the bottom of U-shaped supporting disk, wear out from the socle hole, the cylinder stopper that has the semi-annular handle on the lower extreme of pharynx swab stick is fixed, advance the socle hole to the cylinder stopper, the length of pharynx swab stick will satisfy when sampling by the lid of person's mouth nose of being sampled can not contact the sampling pipe, this pharynx swab divide into two sections from top to bottom, be equipped with connecting portion between two sections from top to bottom, the diameter of connecting portion will be less than the diameter of pharynx swab stick, the upper end of pharynx swab is nylon short fiber fine hair head, tightly connect the neck that a big end down has certain elastic round platform shape below the nylon short fiber fine hair head, round platform shape neck top is thickest, the below is thinnest, nylon short fiber fine hair head is pressed close to round platform shape neck thickest, the diameter of thinnest equals the diameter of pharynx swab, the neck of this round platform shape just in time can advance in the round platform shape of U-shaped supporting disk bottom downthehole, sealed upper segment sampling pipe, separate into two upper and lower sampling space.
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CN202210979166.7A CN115305178B (en) | 2022-08-16 | 2022-08-16 | Integrated form nucleic acid pharynx swab sampling tube that singly adopts |
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CN202210979166.7A CN115305178B (en) | 2022-08-16 | 2022-08-16 | Integrated form nucleic acid pharynx swab sampling tube that singly adopts |
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CN115305178B true CN115305178B (en) | 2023-02-03 |
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Citations (7)
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CA2082355A1 (en) * | 1991-11-08 | 1993-05-09 | Koichiro Saito | Urine sampler |
JP2009148291A (en) * | 1997-05-13 | 2009-07-09 | Erasmus Univ Rotterdam | Molecular detection of chromosome aberrations |
CN204325348U (en) * | 2014-12-16 | 2015-05-13 | 嘉兴凯实生物科技有限公司 | A kind of instrument for extracting nucleic acid nucleic acid-extracting apparatus |
CN112300907A (en) * | 2020-12-16 | 2021-02-02 | 中国医科大学附属盛京医院 | Virus collection tube adopting novel coronavirus nucleic acid mixed collection detection technology |
CN216614638U (en) * | 2021-09-26 | 2022-05-27 | 广州健福医疗科技有限公司 | Virus sampling tube |
CN114668427A (en) * | 2022-03-31 | 2022-06-28 | 河南省人民医院 | Pharynx swab sampling tube for preventing new coronavirus from diffusing through aerosol route and use method thereof |
CN216933285U (en) * | 2021-12-31 | 2022-07-12 | 深圳市远景医疗器械模具有限公司 | Nucleic acid sampling tube convenient to deposit |
-
2022
- 2022-08-16 CN CN202210979166.7A patent/CN115305178B/en active Active
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2082355A1 (en) * | 1991-11-08 | 1993-05-09 | Koichiro Saito | Urine sampler |
JP2009148291A (en) * | 1997-05-13 | 2009-07-09 | Erasmus Univ Rotterdam | Molecular detection of chromosome aberrations |
CN204325348U (en) * | 2014-12-16 | 2015-05-13 | 嘉兴凯实生物科技有限公司 | A kind of instrument for extracting nucleic acid nucleic acid-extracting apparatus |
CN112300907A (en) * | 2020-12-16 | 2021-02-02 | 中国医科大学附属盛京医院 | Virus collection tube adopting novel coronavirus nucleic acid mixed collection detection technology |
CN216614638U (en) * | 2021-09-26 | 2022-05-27 | 广州健福医疗科技有限公司 | Virus sampling tube |
CN216933285U (en) * | 2021-12-31 | 2022-07-12 | 深圳市远景医疗器械模具有限公司 | Nucleic acid sampling tube convenient to deposit |
CN114668427A (en) * | 2022-03-31 | 2022-06-28 | 河南省人民医院 | Pharynx swab sampling tube for preventing new coronavirus from diffusing through aerosol route and use method thereof |
Non-Patent Citations (1)
Title |
---|
提高新型冠状病毒肺炎咽拭子采样和送检质量的对策探讨;李焕梅等;《临床医学工程》;20200910(第09期);88-89 * |
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