CN115252480A - 姜油作为驱蚊剂的用途 - Google Patents
姜油作为驱蚊剂的用途 Download PDFInfo
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/31—Hydrocarbons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/02—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings containing insect repellants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/805—Corresponding aspects not provided for by any of codes A61K2800/81 - A61K2800/95
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Life Sciences & Earth Sciences (AREA)
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Abstract
本发明涉及一种姜油组合物作为驱蚊剂的用途，所述姜油组合物含有姜油和角鲨烷，该驱蚊剂具有无毒、无害、纯天然、驱蚊效果显著、持续时间长等特点。
Description
技术领域
本发明属于日用化学品领域，涉及皮肤外用驱蚊剂组合物，具体涉及一种姜油作为驱蚊剂的用途。
技术背景
蚊子因吸血而成为重要的医学昆虫，是登革热、疟疾、黄热病、丝虫病、脑炎以及很多病毒的中间寄主，通过吸食血液进而传播疾病。蚊子叮咬还引起人体瘙痒，严重影响人类的休息和睡眠质量。夏秋季更是蚊虫肆虐的季节，蚊虫防治是生活中重要的一环。
目前蚊虫防治方法主要有蚊香法和驱蚊剂法，蚊香虽然驱蚊效果比较好，但有一定毒性，损害人体健康；现有的驱蚊剂虽然效果较好，但持续时间短，而且有些化学驱蚊剂对人体有损害。
姜是姜科属开花植物，它的根被广泛用作食物香料，有助消化作用。姜油，又名生姜油，英文名称为Ginger Oil，生姜油以姜的根茎为原料，经干燥、磨碎，水蒸气蒸馏制备，得油率约为1.5％～3.0％。也可用冷磨或冷榨法提取，得油率为0.27％～0.33％，其可用于调配食品香精，在某些化妆品、香皂香精中也可少量使用。姜油为淡黄色液体，带生姜的辣味，相对密度0.877～0.888(15℃)，折光率1.488～1.494，不溶于水、甘油和乙二醇，溶于7倍的95％乙醇，主要成分是姜醇、姜油酮、柠檬醛、甲基庚烯酮、壬醛、辛醛、芳樟醇、香叶醇、龙脑。
角鲨烷(Squalane)分子式C30H62最早是从深海鲨鱼肝脏中提取的角鲨烯经氢化制得一种性能优异的烃类油脂，又名深海鲨鱼肝油。1906年首先由东京工业实验室在鲨鱼肝油中发现。1926年确定了角鲨烷的结构，现已开发出橄榄油来源的角鲨烷。来源于橄榄油的角鲨烷是天然的、可再生的且没有鱼腥味，称为植物角鲨烷。橄榄油来源的角鲨烷是一种天然的润肤油，可作为基础油脂用于膏霜，乳液，彩妆，洗发香波及护发素中，对粉体有优良的分散作用，在防晒产品中可增加产品的SPF值，因其良好润肤性能所以价格昂贵，常用于高档护肤品中。
目前没有姜油和角鲨烷用于驱蚊剂的报道。
发明内容
本发明意外的发现，姜油具有驱蚊作用，姜油和角鲨烷按照特定比例组合后，作为外用驱蚊剂涂抹在皮肤上，具有更优良的驱蚊效果，为此，本发明提供一种姜油组合物。
本发明所述姜油组合物，含有姜油和角鲨烷。
本发明所述的组合物，其中姜油和和角鲨烷的比例为1-10:1-10。
本发明所述的组合物，优选的，其中姜油和和角鲨烷的比例为1-5:1-5。
本发明所述的组合物，最优选的，其中姜油和和角鲨烷的比例为1:1，1：3，1：5，1：7。
本发明所述姜油组合物，制备方法包括将姜油和角鲨烷混合的步骤。
本发明所述的组合物，其中所述的组合物中，还可含有橄榄油等植物油，加入比例为姜油的0.5倍。
本发明所述的组合物，其中所述姜油由生姜根茎作为原料经过水蒸气蒸馏或超临界二氧化碳萃取制备而成。
本发明所述的组合物，其中所述角鲨烷为植物角鲨烷，从橄榄或甘蔗中提取得到。
本发明所述的组合物，其中所述姜油中有效成分6-姜醇含量≥15％、姜辣素含量≥25％；角鲨烷中的有效成分异三十烷C30H62含量≥94％。可以采用GB 8318-87，食品添加剂，生姜油的方法对姜油进行检测，可以采用气相色谱串联质谱法检测角鲨烷的含量,能够有效的控制角鲨烷的质量。
本发明进一步包括，本发明所述的组合物作为驱蚊剂的应用。
本发明进一步包括本发明组合物的使用方法，步骤如下：将姜油组合物均匀涂抹在裸露皮肤表面即可。
本发明组合物作为驱蚊剂具有无毒、无害、纯天然、驱蚊效果显著、持续时间长等优点。
本发明所述姜油和角鲨烷，市面上有售，其制备方法是已知的，有关制备方法以及它们的应用可以见有关的报刊，杂志，网站，专利文献等。其中姜油含姜烯酮、姜烯酚、姜烯、水芹烯、金合欢烯、桉叶油素、龙脑、乙酸龙脑酯、香叶醇、芳樟醇、壬醛、癸醛等天然化合物，挥发性从低到高，特别是低挥发性成分含量高，使得其能强效持久的迷惑蚊虫。
其中角鲨烷作为姜油的辅助成分具有增强驱蚊效果的作用，降低姜油对皮肤的刺激性和灼热感，中和和减少姜油的气味，让人的皮肤感觉舒适，安逸，不影响睡眠。
以下通过实验数据对本发明作进一步的解释和说明。
本发明人于夏天蚊虫肆虐季节在内蒙古某大学的学生宿舍进行驱蚊效果实验，选定一个男生宿舍，一个女生宿舍做实验，每个宿舍6名同学，其中3名同学睡觉前在身体表面涂抹本发明实施例1制备的姜油驱蚊剂，另外3名同学不涂抹作为对照，每个宿舍控制蚊子数量6个，每天晚上22点熄灯到次日6点进行实验，共三天，考查驱蚊效果。
实验1
第一天，男生宿舍，实验结果如下：
| 学生编号 | 是否涂抹本姜油驱蚊剂 | 驱蚊效果 |
| 1 | 是 | 没被叮咬，睡眠质量好 |
| 2 | 否 | 被叮咬，睡眠质量不好 |
| 3 | 是 | 没被叮咬，睡眠质量好 |
| 4 | 否 | 被叮咬，睡眠质量不好 |
| 5 | 是 | 没被叮咬，睡眠好 |
| 6 | 否 | 被叮咬，睡眠不好 |
实验2
第一天，女生宿舍，实验结果如下：
实验3
第二天，男生宿舍，实验结果如下：
| 学生编号 | 是否涂抹本姜油驱蚊剂 | 驱蚊效果 |
| 1 | 是 | 没被叮咬，睡眠质量好 |
| 2 | 否 | 被叮咬，睡眠质量不好 |
| 3 | 是 | 没被叮咬，睡眠质量好 |
| 4 | 否 | 被叮咬，睡眠质量不好 |
| 5 | 是 | 没被叮咬，睡眠质量好 |
| 6 | 否 | 被叮咬，睡眠质量不好 |
实验4
第二天，女生宿舍，实验结果如下：
实验5
第三天，男生宿舍，实验结果如下：
| 学生编号 | 是否涂抹本姜油驱蚊剂 | 驱蚊效果 |
| 1 | 是 | 没被叮咬，睡眠质量好 |
| 2 | 否 | 被叮咬，睡眠质量不好 |
| 3 | 是 | 没被叮咬，睡眠质量好 |
| 4 | 否 | 被叮咬，睡眠质量不好 |
| 5 | 是 | 没被叮咬，睡眠质量好 |
| 6 | 否 | 被叮咬，睡眠质量不好 |
实验6
第三天，女生宿舍，实验结果如下：
| 学生编号 | 是否涂抹本姜油驱蚊剂 | 驱蚊效果 |
| 1 | 是 | 没被叮咬，睡眠质量好 |
| 2 | 否 | 被叮咬，睡眠质量不好 |
| 3 | 是 | 没被叮咬，睡眠质量好 |
| 4 | 否 | 被叮咬，睡眠质量不好 |
| 5 | 是 | 没被叮咬，睡眠质量好 |
| 6 | 否 | 被叮咬，睡眠质量不好 |
协同增效实验：
实验药物：本发明实施例1制备的姜油驱蚊剂，本发明对比例1制备的姜油驱蚊剂
实验方法
于夏天蚊虫肆虐季节在内蒙古某大学的学生宿舍进行实施例1与对比例1驱蚊效果对比实验，选定一个男生宿舍，一个女生宿舍做实验，每个宿舍6名同学，其中3名同学睡觉前在身体表面涂抹本发明实施例1制备的姜油驱蚊剂，另外3名同学涂抹对比例1制备的姜油驱蚊剂，每个宿舍控制蚊子数量6个，每天晚上22点熄灯到次日6点进行实验，共三天，考查驱蚊效果。
实验效果：
第一天，男生宿舍，实验结果如下：
第一天，女生宿舍，实验结果如下：
第二天，男生宿舍，实验结果如下：
第二天，女生宿舍，实验结果如下：
第三天，男生宿舍，实验结果如下：
第三天，女生宿舍，实验结果如下：
结果显示，使用本发明实施例1产品与对比例1产品驱蚊效果相当，但实施例1产品的肤感优于对比例1产品。
具体实施方式
实施例1
配方
姜油：1份
角鲨烷：1份
配制方法
将姜油与角鲨烷混合均匀，加入0.5份橄榄油搅拌至澄清透明即可。
对比例1
配方
姜油
配制方法
以纯姜油为驱蚊剂。
实施例2
配方
姜油：1份
角鲨烷：3份
配制方法
将姜油与角鲨烷混合均匀，加入0.5份橄榄油搅拌至澄清透明即可。
实施例3
配方
姜油：1份
角鲨烷：5份
配制方法
将姜油与角鲨烷混合均匀，加入0.5份橄榄油搅拌至澄清透明即可。
实施例4
配方
姜油：1份
角鲨烷：7份
配制方法
将姜油与角鲨烷混合均匀，加入0.5份橄榄油搅拌至澄清透明即可。
Claims (10)
1.一种姜油组合物，含有姜油和角鲨烷。
2.根据权利要求1所述的组合物，姜油和角鲨烷的比例为1-10:1-10。
3.根据权利要求1所述的组合物，姜油和角鲨烷的比例为1-5:1-5。
4.根据权利要求1所述的组合物，姜油和角鲨烷的比例为1:1，1：3，1：5，1：7。
5.根据权利要求4所述的组合物，其中，还可含有橄榄油，加入比例为姜油的0.5倍。
6.根据权利要求1所述的组合物，其中所述姜油由生姜根茎作为原料经过水蒸气蒸馏或超临界二氧化碳萃取制备而成。
7.根据权利要求1所述的组合物，其中所述角鲨烷为植物角鲨烷，从橄榄或甘蔗中提取得到。
8.根据权利要求1所述的组合物，其中所述姜油中有效成分6-姜醇含量为15％、姜辣素含量为25％；角鲨烷中的有效成分异三十烷C30H62含量为94％。
9.权利要求1所述的组合物作为驱蚊剂的应用。
10.权利要求1所述的组合物的使用方法，步骤如下：将姜油组合物均匀涂抹在裸露皮肤表面即可。
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20200323221A1 (en) * | 2019-04-10 | 2020-10-15 | Dien Truc Essential Oil Company Limited | Multipurpose mosquito repellant composition and method of manufacturing the same |
| CN113662893A (zh) * | 2021-08-20 | 2021-11-19 | 中山中研化妆品有限公司 | 温感面膜及其制备方法 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20200323221A1 (en) * | 2019-04-10 | 2020-10-15 | Dien Truc Essential Oil Company Limited | Multipurpose mosquito repellant composition and method of manufacturing the same |
| CN113662893A (zh) * | 2021-08-20 | 2021-11-19 | 中山中研化妆品有限公司 | 温感面膜及其制备方法 |
Non-Patent Citations (1)
| Title |
|---|
| 美丽修行: "《吸血昆虫的化学防护》", vol. 1, 军事医学科学出版社, pages: 180 * |
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