Disclosure of Invention
The embodiment of the application provides a human brain light stimulation device and a system thereof, which are used for solving the problems that in the existing treatment of the degenerative disease of the central nervous system, the operation of craniotomy on the brain is needed, the operation is more complicated and the cost is high.
The embodiment of the application provides a human brain light stimulation device, includes:
the conveying mechanism comprises a piston rod, a push rod and a guide piece, the output end of the piston rod is connected with the input end of the push rod, a through hole is formed in the middle of the guide piece, and the output end of the push rod penetrates out of the through hole of the guide piece;
the implantation mechanism comprises a shell, a light source, a power supply and a control module, wherein a cavity is arranged in the shell, the control module and the power supply are both connected to the inner wall of the cavity, the input end of the light source is electrically connected with the output end of the control module, and the output end of the power supply is respectively electrically connected with the input end of the light source and the input end of the control module;
one end of the shell is detachably connected with the output end of the push rod, and the other end of the shell is used for being connected to the inner cavity wall of the sphenoid sinus; the maximum cross section size of the implantation mechanism is larger than the cross section size of the through hole at the output end of the push rod; the light source is used for emitting near infrared light to the deep part of the brain.
Optionally, the shell includes printing opacity casing, clamping jaw and shell fragment, the appearance chamber is established the inside of printing opacity casing, the clamping jaw passes through the shell fragment is connected on the outer wall of printing opacity casing, the bottom of clamping jaw is pegged graft the output of push rod, the clamping jaw part penetrates in the through-hole of guide.
Optionally, a light source cover is connected to an outer wall of the light source, and the light source cover is used for converging light rays or diverging light rays.
Optionally, the guide piece includes an empty section of thick bamboo and flexible hose, the output of an empty section of thick bamboo is connected the input of flexible hose, an empty section of thick bamboo with the centre of flexible hose all is equipped with the through-hole, the output of push rod is followed the input of an empty section of thick bamboo penetrates, the output of push rod is followed in proper order in the through-hole of an empty section of thick bamboo and wear out in the through-hole of flexible hose.
Optionally, an opening is provided at the output end of the flexible hose, and the clamping jaw partially penetrates into the opening.
Optionally, a protrusion is arranged on the outer wall of the clamping jaw and abuts against the inner wall of the opening.
Optionally, a clamping groove is formed in the outer wall of the output end of the piston rod, a clamping block is arranged on the outer wall of the input end of the push rod, and the clamping block is clamped in the clamping groove.
Optionally, the shell includes printing opacity casing, clamping jaw and telescopic link, the appearance chamber is established the inside of printing opacity casing, the inner wall of clamping jaw passes through the telescopic link is connected on the outer wall of printing opacity casing, the bottom of clamping jaw is pegged graft the output of push rod, the telescopic link electricity is connected control module, the clamping jaw part penetrates in the through-hole of guide.
The embodiment of the present application further provides a human brain light stimulation system, including:
a human brain light stimulation apparatus as described in any one of the above;
the camera is connected to the outer wall of the bottom end of the shell and used for collecting image information of the inner cavity of the sphenoidal sinus;
the communication module is connected to the inner wall of the shell, is electrically connected with the control module and the camera and is used for transmitting the image information of the inner cavity of the sphenoidal sinus to the outside;
the upper computer is arranged outside the human brain and is in wireless connection with the communication module and used for receiving the image information of the sphenoid sinus inner cavity and feeding back a control instruction according to the image information of the sphenoid sinus inner cavity.
Optionally, the upper computer includes a processing module and a display module, the processing module is wirelessly connected to the communication module, and the communication module is electrically connected to the display module.
According to the human brain light stimulation device provided by the embodiment of the application, the light source in the implantation mechanism is conveyed into the cavity of the sphenoid sinus of a patient through the piston rod, the guide piece and the push rod in the conveying mechanism, then the push rod and the implantation mechanism are disassembled, so that the shell of the implantation mechanism is abutted against the cavity of the sphenoid sinus, and then the control module controls the light source to continuously emit near infrared light to the deep part of the brain, so that the near infrared light stimulates and treats the central nerve of the brain; the whole process does not need craniotomy, and only needs to extend the implantation mechanism into the sphenoid sinus cavity from the nose, the device is easy to operate, and the treatment cost of a patient can be reduced.
Detailed Description
The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application. It is to be understood that the embodiments described are only a few embodiments of the present application and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present application.
The embodiment of the application provides a human brain light stimulation device and a system thereof, which are used for solving the problems that in the existing treatment of the degenerative disease of the central nervous system, the operation of craniotomy on the brain is needed, the operation is more complicated and the cost is high. The following description will be made with reference to the accompanying drawings.
As shown in fig. 1, an embodiment of the present invention provides a human brain light stimulation device, and fig. 1 is a schematic structural diagram of the human brain light stimulation device, wherein the human brain light stimulation device can be applied to various central nervous system degenerative diseases, for example, a parkinson patient, the human brain light stimulation device can emit near infrared light deep into the brain of the patient, the near infrared light is an electromagnetic wave between visible light and intermediate infrared light, and for example, the near infrared light with a wavelength of 670nm can activate photoreceptors such as cytochrome c oxidase, thereby regulating human metabolism. Therefore, near infrared light can be transmitted between tissues of the human body, can pass through intracranial tissues and reach deep parts of the brain; the near infrared light reaching the deep part of the brain can stimulate the central nervous system, regulate the metabolism of the patient and protect the central nervous system of the patient, so that the patient is prevented from appearing Parkinson's disease, and the quick and stable treatment effect is achieved.
In some embodiments, as shown in fig. 1-3, fig. 2 is an exploded view of a human brain light stimulation device, and fig. 3 is a schematic structural view of an implant mechanism 2 of the human brain light stimulation device; the human brain light stimulation device comprises a conveying mechanism 1 and an implantation mechanism 2; the conveying mechanism 1 comprises a piston rod 11, a push rod 12 and a guide piece 13, wherein the output end of the piston rod 11 is connected with the input end of the push rod 12, a through hole is formed in the middle of the guide piece 13, and the output end of the push rod 12 penetrates out of the through hole of the guide piece 13; the implanting mechanism 2 comprises a shell 21, a light source 22, a power supply 23 and a control module 24, wherein a containing cavity 211 is arranged in the shell 21, the control module 24 and the power supply 23 are both connected to the inner wall of the containing cavity 211, the light source 22 is electrically connected with the control module 24, and the output end of the power supply 23 is respectively electrically connected with the light source 22 and the control module 24; one end of the shell 21 is detachably connected with the output end of the push rod 12, and the other end of the shell 21 is connected to the inner cavity wall of the sphenoidal sinus; the maximum section size of the implantation mechanism 2 is larger than the section size of the through hole at the output end of the push rod 12; near-infrared light can be emitted by the light source 22 in the direction of the brain, which can pass through the intracranial tissue to reach deep in the brain.
When a patient is treated, the matched implantation mechanism 2 can be formulated according to the symptoms of the patient, the implantation mechanism 2 is assembled on the conveying mechanism 1, then the implantation mechanism 2 is placed in the nose of the patient, the implantation mechanism 2 is conveyed into the sphenoid sinus cavity of the patient through the piston rod 11 and the push rod 12 under the guiding of the guide piece 13, then the position of the guide piece 13 is kept, the piston rod 11 is pulled back, the piston rod 11 drives the implantation mechanism 2 to move outwards through the push rod 12, and as the size of the implantation mechanism 2 is larger than that of the through hole, a reaction force is applied to the implantation mechanism 2 by the output end of the guide piece 13, so that the push rod 12 is separated from the implantation mechanism 2, finally the implantation mechanism 2 falls into the sphenoid sinus cavity of the patient, and the push rod 12 and the guide piece 13 are taken out. In operation, control module 24 within implant mechanism 2 can control light source 22 to emit near infrared light that can pass through intracranial tissue to deep within the brain and stimulate the central nervous system deep within the brain of the patient, thereby treating the patient.
In this embodiment, the accommodating cavity 211 is used for accommodating components of the device, and can protect the components; the material of the housing 21 may be non-biodegradable polymer or alloy, such as polyurethane, stainless steel, titanium, etc. The shell 21 can also adopt an integrated into one piece structure, the head of the shell 21 is designed into a cylinder with the diameter of 3mm, the tail of the shell 21 is provided with a cylinder handle, the bottom end of the cylinder handle is provided with a groove, and the output end of the push rod 12 is inserted into the groove. The power supply 23 is a micro battery, and the micro battery supplies power to the control module 24 and the light source 22 through a micro power interface. The light source 22 adopts a near-infrared light source with the diameter of 1mm, and the light source 22 can continuously emit near-infrared light with the wave band of 650-2500 nm to the deep part of the brain.
As shown in fig. 1 to 6, based on the above embodiments, the present application provides the following embodiments, fig. 4 is a first structural schematic diagram of an implantation mechanism 2 in a human brain light stimulation apparatus, fig. 5 is a second structural schematic diagram of the implantation mechanism 2 in the human brain light stimulation apparatus, and fig. 6 is a third structural schematic diagram of the implantation mechanism 2 in the human brain light stimulation apparatus.
In one embodiment, the housing 21 includes a light-transmitting casing 212, a clamping jaw 213 and a spring plate 214, the cavity 211 is disposed inside the light-transmitting casing 212, the clamping jaw 213 is connected to an outer wall of the light-transmitting casing 212 through the spring plate 214, a bottom end of the clamping jaw 213 is inserted into an output end of the push rod 12, and the clamping jaw 213 partially penetrates into a through hole of the guide 13; the outer wall of the light source 22 is connected with a light source cover 221, and the light source cover 221 is used for converging or diverging light. When the delivery mechanism 1 and the implantation mechanism 2 are assembled, the clamping jaw 213 is partially placed in the through hole of the guide member 13, the clamping jaw 213 is squeezed by the inner wall of the through hole, at this time, the elastic sheet 214 is in a compressed state, and the clamping jaw 213 on the light-transmitting shell 212 is in a contracted state; after the implantation mechanism 2 falls into the sphenoid sinus cavity, the elastic sheet 214 is deformed again, the clamping jaw 213 is unfolded in the sphenoid sinus cavity and is attached to the wall of the inner cavity of the sphenoid sinus, the control module 24 controls the light source 22 to emit near-infrared light, and the near-infrared light can be transmitted into the sphenoid sinus cavity from the light-transmitting shell 212 and can penetrate through intracranial tissues to reach the deep part of the brain.
In this embodiment, the clamping jaws 213 may be several and are uniformly distributed on the sidewall of the bottom end of the transparent casing 212. In specific implementation, the number of the clamping jaws 213 is set to be eight, the eight clamping jaws 213 are uniformly installed on the side wall of the bottom end of the light-transmitting housing 212, the diameter of the antral sphenoid cavity of the patient is about 8mm, the diameter of the antral sphenoid ostium of the patient is about 5mm, and the cross-sectional size of the through hole at the output end of the push rod 12 is set to be 4.4mm; the cross-sectional dimension of the housing 21 enclosed by the eight jaws 213 is set to 4.5mm when the jaws 213 are compressed, and 8.2mm to 8.4mm when the jaws 213 are naturally spread. The light source cover 221 can fix the light source 22, gather light emitted from the light source 22, and emit the gathered light from the light-transmitting housing 212; the light source cover 221 can fix the light source 22, the light source cover 221 can be made of metal or alloy with light reflecting performance, the light transmitting surface of the light source cover 221 can be processed into a mirror surface, and the light source cover 221 can converge light or diverge light to near infrared light according to specific use scenes, so that the transmission effect and the use performance of the light source cover are guaranteed. The housing 212 may be made of polymethyl methacrylate, which can ensure the transmission effect of the light source 22.
Wherein, a camera and a signal transmitting and receiving device can be embedded into the outer wall of the clamping jaw 213, an angle regulator is arranged in the through hole at the output end of the guide piece 13, the camera is connected with the signal transmitting and receiving device, the signal transmitting and receiving device is connected with the control module 24 and an external terminal, and the angle regulator is connected with the control module; before the implantation mechanism 2 drops, the angle regulator can regulate the rotation angle of the implantation mechanism 2, so that the light source 22 is just aligned to the deep part of the brain, after the implantation mechanism 2 drops, the camera can collect the light information transmitted to the inner cavity wall of the sphenoid sinus by the light source 22 and transmit the collected light information to an external terminal through the signal transmitting receiver, the external terminal can analyze the collected light information, judge that the light source 22 is aligned to the deep part of the brain and send a control instruction to the signal transmitting receiver, the signal transmitting receiver transmits the control instruction to the control module 24, and the control module 24 controls the angle regulator to regulate the abutting position of the clamping jaw 213, so that the light source 22 is aligned to the deep part of the brain, and the treatment effect can be improved; meanwhile, the light source cover 221 can further condense the light emitted from the light source 22, so that the light can be more intensively emitted to the deep part of the brain, and the treatment effect of the patient is improved.
In addition, the clamping jaws 213 can also adopt four C-shaped structures and uniformly surround the side wall of the bottom end of the light-transmitting shell 212. After the implantation mechanism 2 is delivered to the sphenoid sinus cavity, the doctor can push out the implantation mechanism 2 through the piston rod 11, so that each clamping jaw 213 is unfolded and abuts against the wall of the sphenoid sinus cavity; the outer surfaces of the clamping jaws 213 may also be frosted to increase the friction between the clamping jaws 213 and the walls of the sphenoid sinus cavity, thereby preventing positional shifting of the implantation mechanism 2.
As shown in fig. 4 to 6, in the present embodiment, the spreading direction of the clamping jaw 213 may be a direction toward the light source 22, a direction toward the push rod 12, or another installation direction, and the present application is not limited herein.
As shown in fig. 1-3, in one embodiment, the guiding element 13 comprises an empty cylinder 131 and a flexible hose 132, an output end of the empty cylinder 131 is connected to an input end of the flexible hose 132, through holes are formed in the middle of the empty cylinder 131 and the flexible hose 132, an output end of the push rod 12 penetrates through the input end of the empty cylinder 131, and an output end of the push rod 12 sequentially penetrates through the through hole of the empty cylinder 131 and the through hole of the flexible hose 132; the output end of the flexible hose 132 is provided with an opening in which the clamping jaw 213 is partially placed; the outer wall of the clamping jaw 213 is provided with a bulge which is abutted against the inner wall of the opening; the outer wall of the output end of the piston rod 11 is provided with a clamping groove 111, the outer wall of the input end of the push rod 12 is provided with a clamping block 121, and the clamping block 121 is clamped in the clamping groove 111.
When the implantation mechanism 2 is used, the fixture block 121 at the input end of the push rod 12 is clamped in the fixture groove 111 on the outer wall of the output end of the piston rod 11, the output end of the push rod 12 sequentially penetrates out of the through hole of the hollow cylinder 131 and the through hole of the flexible hose 132, the implantation mechanism 2 is inserted into the output end of the push rod 12, the clamping jaw 213 part of the implantation mechanism 2 is placed in the through hole of the flexible hose 132, and the protrusion on the clamping jaw 213 abuts against the inner wall of the opening; then under the guidance of the hollow cylinder 131 and the flexible hose 132, the output end of the push rod 12 and the implantation mechanism 2 extend into the cavity of the sphenoid sinus of the patient; then, the piston rod 11 is pulled back, and the implantation mechanism 2 is separated from the push rod 12 at the opening because the maximum cross-sectional dimension of the implantation mechanism 2 is smaller than the dimension of the opening; finally, the control module 24 controls the light source 22 to emit near-infrared light, the near-infrared light can penetrate through the inner cavity wall of the sphenoidea and intracranial tissues and reach the deep part of the brain, and the near-infrared light can stimulate the central nerve at the deep part of the brain of the patient, so that the treatment effect on the patient is realized.
As shown in fig. 1 to 3, in one embodiment, the housing 21 includes a light-transmitting casing 212, a clamping jaw 213 and a telescopic rod, the accommodating cavity 211 is disposed inside the light-transmitting casing 212, an inner wall of the clamping jaw 213 is connected to an outer wall of the light-transmitting casing 212 through the telescopic rod, a bottom end of the clamping jaw 213 is inserted into an output end of the push rod 12, the telescopic rod is electrically connected to the control module 24, and the clamping jaw 213 is partially inserted into the through hole of the guide 13.
In this embodiment, the telescopic rod can be an electric telescopic rod; the implanting mechanism 2 drops in front of the sphenoid sinus cavity, the electric telescopic rod and the clamping jaw 213 are in a contraction state and are installed at the output end of the push rod 12, when the implanting mechanism 2 drops in the sphenoid sinus cavity, the control module 24 controls the electric telescopic rod to extend according to the size of the sphenoid sinus cavity of the patient, and the electric telescopic rod can enable the clamping jaw 213 to be unfolded to enable the clamping jaw 213 to abut against the inner cavity wall of the sphenoid sinus of the patient, so that the implanting mechanism 2 is prevented from sliding in the position in the sphenoid sinus cavity of the patient.
As shown in fig. 1, 2, 3 and 7, fig. 7 is a block diagram of the signal transmission structure of the components in the human brain light stimulation system; the embodiment of the application also provides a human brain light stimulation system, which comprises the human brain light stimulation device, the camera 3, the communication module 4 and the upper computer 5 in the embodiment; the camera 3 can be connected to the outer wall of the clamping jaw 213, and the camera 3 can acquire image information of the inner cavity of the sphenoidal sinus; the communication module 4 is connected to the inner wall of the shell 21, the communication module 4 is electrically connected with the control module 24 and the camera 3, and the communication module 4 can transmit the image information of the cavity of the sphenoidal sinus to the outside; the upper computer 5 is arranged outside the human brain, the upper computer 5 is wirelessly connected with the communication module 4, the upper computer 5 can receive image information of the sphenoidal sinus cavity and feed back a control instruction according to the image information of the sphenoidal sinus cavity, after the communication module 4 receives the control instruction sent by the upper computer 5, the communication module 4 can transmit the control instruction to the control module 24, the control module 24 can adjust the wavelength of the light source 22 in the human brain light stimulation device according to the instruction, and infrared light energy with different wavelengths can perform appropriate treatment according to different symptoms of a patient, so that the patient can achieve the optimal treatment effect; the power supply 23 can supply power to the camera 3 and the communication module 4.
In this embodiment, the upper computer 5 includes a processing module 51 and a display module 52, the processing module 51 is wirelessly connected to the communication module 4, and the communication module 4 is electrically connected to the display module 52.
When the implantation mechanism 2 is used, the clamping block 121 at the input end of the push rod 12 is clamped in the clamping groove 111 on the outer wall of the output end of the piston rod 11, the output end of the push rod 12 sequentially penetrates out of the through hole of the hollow cylinder 131 and the through hole of the flexible hose 132, the implantation mechanism 2 is inserted into the output end of the push rod 12, and the clamping jaw 213 part of the implantation mechanism 2 penetrates into the through hole of the flexible hose 132, so that the protrusion on the clamping jaw 213 is abutted against the inner wall of the opening; then under the guidance of the hollow cylinder 131 and the flexible hose 132, the output end of the push rod 12 and the implantation mechanism 2 extend into the cavity of the sphenoid sinus of the patient; then, the piston rod 11 is pulled back, and the implantation mechanism 2 is separated from the push rod 12 at the opening because the maximum cross-sectional size of the implantation mechanism 2 is smaller than the size of the opening; finally, the control module 24 controls the light source 22 to emit near-infrared light, which can penetrate through intracranial tissues to reach the deep part of the brain and stimulate the central nerve of the deep part of the brain of the patient, thereby treating the patient. In work, the camera 3 can collect image information of the inner cavity of the sphenoid sinus of a patient in real time, the image information of the inner cavity of the sphenoid sinus can be transmitted to an external upper computer 5 through the communication module 4, the processing module 51 in the upper computer 5 can analyze the received image information, after analysis, the processing module 51 can wirelessly transmit a control instruction to the communication module 4 in the implantation mechanism 2, the communication module 4 transmits the control instruction to the control module 24, and the control module 24 performs suitability adjustment on the human brain light stimulation device, so that the treatment effect of the patient is improved; meanwhile, the image information collected by the camera 3 can also be wirelessly transmitted to the display module 52 in the upper computer 5 through the communication module 4, thereby facilitating the diagnosis of doctors.
In the foregoing embodiments, the descriptions of the respective embodiments have respective emphasis, and for parts that are not described in detail in a certain embodiment, reference may be made to related descriptions of other embodiments.
In the description of the present application, the terms "first", "second" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or as implying a number of the indicated technical features. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more features.
The human brain light stimulation device provided by the embodiment of the present application is described in detail above, and the principle and the embodiment of the present application are explained in the present application by applying specific examples, and the description of the above embodiment is only used to help understanding the method and the core concept of the present application; meanwhile, for those skilled in the art, according to the idea of the present application, there may be variations in the specific embodiments and the application scope, and in summary, the content of the present specification should not be construed as a limitation to the present application.