CN115176156A - 预制微粒及其前体的文库 - Google Patents

预制微粒及其前体的文库 Download PDF

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Publication number
CN115176156A
CN115176156A CN202080096605.9A CN202080096605A CN115176156A CN 115176156 A CN115176156 A CN 115176156A CN 202080096605 A CN202080096605 A CN 202080096605A CN 115176156 A CN115176156 A CN 115176156A
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CN
China
Prior art keywords
analyte
microparticles
library
detection
specific
Prior art date
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Pending
Application number
CN202080096605.9A
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English (en)
Chinese (zh)
Inventor
云根·恩尔曼川特
伊万·伦卡维克
凯瑟琳·斯蒂尔莫茨
斯蒂芬·胡博得
托马斯·艾林戈
苏珊·科林格
奥利沃·莱姆茨
莉亚·坎茨
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Brink Co
Original Assignee
Brink Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Brink Co filed Critical Brink Co
Publication of CN115176156A publication Critical patent/CN115176156A/zh
Pending legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1093—General methods of preparing gene libraries, not provided for in other subgroups
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Plant Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
CN202080096605.9A 2019-12-16 2020-12-15 预制微粒及其前体的文库 Pending CN115176156A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP19216596.7 2019-12-16
EP19216596.7A EP3839509A1 (en) 2019-12-16 2019-12-16 A library of prefabricated microparticles and precursors thereof
PCT/EP2020/086171 WO2021122563A1 (en) 2019-12-16 2020-12-15 A library of prefabricated microparticles and precursors thereof

Publications (1)

Publication Number Publication Date
CN115176156A true CN115176156A (zh) 2022-10-11

Family

ID=68917651

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202080096605.9A Pending CN115176156A (zh) 2019-12-16 2020-12-15 预制微粒及其前体的文库

Country Status (10)

Country Link
US (1) US20230126528A1 (https=)
EP (2) EP3839509A1 (https=)
JP (1) JP7843040B2 (https=)
KR (1) KR20220114623A (https=)
CN (1) CN115176156A (https=)
AU (1) AU2020403850A1 (https=)
BR (1) BR112022011674A2 (https=)
CA (1) CA3161636A1 (https=)
IL (1) IL293744B2 (https=)
WO (1) WO2021122563A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN119080402A (zh) * 2024-08-27 2024-12-06 成都赋仁生物科技有限公司 复合树脂基底的单分子阵列芯片及其制备方法

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4177352A1 (en) 2021-11-05 2023-05-10 Blink AG A microsphere comprising a first material and a second material
EP4252907A1 (en) 2022-03-30 2023-10-04 Blink AG A method for arranging microspheres in a non-aqueous liquid phase
KR20250132854A (ko) * 2024-02-29 2025-09-05 고려대학교 산학협력단 타겟과 결합된 아이디-마이크로파티클를 이용한 병렬 약물스크리닝 방법

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001044812A1 (en) * 1999-12-15 2001-06-21 Icogen Corporation Method for the simultaneous analysis and detection of multiple analytes by micro identification
US20190331677A1 (en) * 2016-12-30 2019-10-31 Blink Ag Prefabricated microparticle for performing a detection of an analyte

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2513899C (en) 2003-01-29 2013-03-26 454 Corporation Methods of amplifying and sequencing nucleic acids
US20050239108A1 (en) 2004-02-23 2005-10-27 University Of Maryland, Baltimore Immuno-PCR method for the detection of a biomolecule in a test sample
US9822393B2 (en) 2013-03-08 2017-11-21 Bio-Rad Laboratories, Inc. Compositions, methods and systems for polymerase chain reaction assays
WO2011056185A2 (en) 2009-11-04 2011-05-12 President And Fellows Of Harvard College Reactivity-dependent and interaction-dependent pcr
KR101932628B1 (ko) 2010-06-07 2018-12-27 파이어플라이 바이오웍스, 인코포레이티드 후­혼성 표지화 및 범용 코드화에 의한 핵산 검출 및 정량화
WO2015200541A1 (en) 2014-06-24 2015-12-30 Bio-Rad Laboratories, Inc. Digital pcr barcoding
AU2015323168B2 (en) 2014-09-22 2020-07-02 Japan Science And Technology Agency Method for detecting target molecule, and kit for use in said method

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001044812A1 (en) * 1999-12-15 2001-06-21 Icogen Corporation Method for the simultaneous analysis and detection of multiple analytes by micro identification
US20190331677A1 (en) * 2016-12-30 2019-10-31 Blink Ag Prefabricated microparticle for performing a detection of an analyte

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
GAELLE C. LE GOFF等: "Hydrogel microparticles for biosensing", EUROPEAN POLYMER JOURNAL, vol. 72, no. 1, 1 November 2015 (2015-11-01), pages 386 - 412, XP055538456, DOI: 10.1016/j.eurpolymj.2015.02.022 *
NAK WON CHOI等: "Multiplexed Detection of mRNA Using Porosity-Tuned Hydrogel Microparticles", ANALYTICAL CHEMISTRY, vol. 84, no. 21, 28 September 2012 (2012-09-28), pages 9370 - 9378, XP055373601, DOI: 10.1021/ac302128u *
YOON HO ROH等: "Microfluidic Fabrication of Encoded Hydrogel Microparticles for Application in Multiplex Immunoassay", BIOCHIP JOURNAL, vol. 13, no. 1, 12 March 2019 (2019-03-12), pages 64 - 81, XP036740168, DOI: 10.1007/s13206-019-3104-z *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN119080402A (zh) * 2024-08-27 2024-12-06 成都赋仁生物科技有限公司 复合树脂基底的单分子阵列芯片及其制备方法

Also Published As

Publication number Publication date
KR20220114623A (ko) 2022-08-17
BR112022011674A2 (pt) 2022-10-11
IL293744A (en) 2022-08-01
JP7843040B2 (ja) 2026-04-09
US20230126528A1 (en) 2023-04-27
WO2021122563A1 (en) 2021-06-24
JP2023506260A (ja) 2023-02-15
CA3161636A1 (en) 2021-06-24
IL293744B2 (en) 2026-02-01
IL293744B1 (en) 2025-10-01
EP3839509A1 (en) 2021-06-23
EP4078180A1 (en) 2022-10-26
AU2020403850A1 (en) 2022-07-07

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