CN115155473A - 长形固相体 - Google Patents

长形固相体 Download PDF

Info

Publication number
CN115155473A
CN115155473A CN202210266446.3A CN202210266446A CN115155473A CN 115155473 A CN115155473 A CN 115155473A CN 202210266446 A CN202210266446 A CN 202210266446A CN 115155473 A CN115155473 A CN 115155473A
Authority
CN
China
Prior art keywords
solid phase
elongate
beads
strips
enclosure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202210266446.3A
Other languages
English (en)
Chinese (zh)
Inventor
A·普利维
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nova Junior Manufacturing Co.,Ltd.
NOVA LABORATORY Co.,Ltd.
Original Assignee
Swedish Biomimetics 3000 Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Swedish Biomimetics 3000 Ltd filed Critical Swedish Biomimetics 3000 Ltd
Publication of CN115155473A publication Critical patent/CN115155473A/zh
Pending legal-status Critical Current

Links

Images

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J8/00Chemical or physical processes in general, conducted in the presence of fluids and solid particles; Apparatus for such processes
    • B01J8/02Chemical or physical processes in general, conducted in the presence of fluids and solid particles; Apparatus for such processes with stationary particles, e.g. in fixed beds
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J8/00Chemical or physical processes in general, conducted in the presence of fluids and solid particles; Apparatus for such processes
    • B01J8/02Chemical or physical processes in general, conducted in the presence of fluids and solid particles; Apparatus for such processes with stationary particles, e.g. in fixed beds
    • B01J8/06Chemical or physical processes in general, conducted in the presence of fluids and solid particles; Apparatus for such processes with stationary particles, e.g. in fixed beds in tube reactors; the solid particles being arranged in tubes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J8/00Chemical or physical processes in general, conducted in the presence of fluids and solid particles; Apparatus for such processes
    • B01J8/16Chemical or physical processes in general, conducted in the presence of fluids and solid particles; Apparatus for such processes with particles being subjected to vibrations or pulsations
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/045General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers using devices to improve synthesis, e.g. reactors, special vessels
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/047Simultaneous synthesis of different peptide species; Peptide libraries
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/00279Features relating to reactor vessels
    • B01J2219/00281Individual reactor vessels
    • B01J2219/00295Individual reactor vessels the reactor vessels having pervious side walls
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/00457Dispensing or evacuation of the solid phase support
    • B01J2219/00459Beads
    • B01J2219/00461Beads and reaction vessel together
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/00497Features relating to the solid phase supports
    • B01J2219/00513Essentially linear supports
    • B01J2219/00518Essentially linear supports in the shape of tapes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718Type of compounds synthesised
    • B01J2219/0072Organic compounds
    • B01J2219/00722Nucleotides
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718Type of compounds synthesised
    • B01J2219/0072Organic compounds
    • B01J2219/00725Peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Materials For Medical Uses (AREA)
  • Manufacture Of Porous Articles, And Recovery And Treatment Of Waste Products (AREA)
  • Devices And Processes Conducted In The Presence Of Fluids And Solid Particles (AREA)
  • Peptides Or Proteins (AREA)
CN202210266446.3A 2016-11-22 2017-11-20 长形固相体 Pending CN115155473A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB1619713.9 2016-11-22
GBGB1619713.9A GB201619713D0 (en) 2016-11-22 2016-11-22 Elongate solid phase body
PCT/GB2017/053480 WO2018096321A1 (en) 2016-11-22 2017-11-20 Elongate solid phase body
CN201780072143.5A CN110234427A (zh) 2016-11-22 2017-11-20 长形固相体

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN201780072143.5A Division CN110234427A (zh) 2016-11-22 2017-11-20 长形固相体

Publications (1)

Publication Number Publication Date
CN115155473A true CN115155473A (zh) 2022-10-11

Family

ID=57993916

Family Applications (2)

Application Number Title Priority Date Filing Date
CN202210266446.3A Pending CN115155473A (zh) 2016-11-22 2017-11-20 长形固相体
CN201780072143.5A Pending CN110234427A (zh) 2016-11-22 2017-11-20 长形固相体

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN201780072143.5A Pending CN110234427A (zh) 2016-11-22 2017-11-20 长形固相体

Country Status (8)

Country Link
US (1) US11529603B2 (enExample)
EP (1) EP3544725A1 (enExample)
JP (1) JP2020508203A (enExample)
CN (2) CN115155473A (enExample)
AU (2) AU2017365927A1 (enExample)
CA (1) CA3043545A1 (enExample)
GB (1) GB201619713D0 (enExample)
WO (1) WO2018096321A1 (enExample)

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4631211A (en) * 1985-03-25 1986-12-23 Scripps Clinic & Research Foundation Means for sequential solid phase organic synthesis and methods using the same
WO1999004895A1 (en) * 1997-07-24 1999-02-04 Argonaut Technologies, Inc. Compositions for the storage and delivery of solid phase reactive particles and methods of using the same
WO2000015653A2 (en) * 1998-09-16 2000-03-23 Central Research Laboratories Limited Apparatus for, and method of, storing a plurality of chemical compounds
US20050048667A1 (en) * 2003-08-29 2005-03-03 Brett Ellman Method of forming and using solid-phase support
US7338768B1 (en) * 1997-11-12 2008-03-04 Nanomics Biosystems Pty. Ltd. Carrier-reporter bead assemblies
CN101730582A (zh) * 2007-07-03 2010-06-09 瑞典仿生3000有限公司 固相反应方法及装置
CN102271801A (zh) * 2009-01-07 2011-12-07 瑞典仿生3000有限公司 双移动相设备和方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5235028A (en) 1990-08-31 1993-08-10 University Of Minnesota Polyethylene glycol derivatives for solid-phase applications
NL1006813C1 (nl) * 1997-08-20 1998-01-21 Sipke Wadman Verpakkingen voor een vast reactie-draagmedium.
GB9726983D0 (en) * 1997-12-22 1998-02-18 Cambridge Combinatorial Ltd Novel substrate for solid phase combinatorial library generation, apparatus for preparing addressable portions thereof, and a method of preparing a library
US6872535B2 (en) 1998-05-20 2005-03-29 Aventis Pharmaceuticals Inc. Three-dimensional array of supports for solid-phase parallel synthesis and method of use
US20030068621A1 (en) * 2001-10-04 2003-04-10 Jonathan Briggs Method and device for producing oligonucleotide arrays
GB0614727D0 (en) * 2006-07-25 2006-09-06 Chromatide Ltd Solid support
EP2478369A4 (en) * 2009-03-25 2012-11-14 Lyzer Diagnostics Inc APPARATUS AND METHODS FOR ANALYZING VARIABLES RELATED TO FLUIDS
DK2418072T3 (en) * 2010-08-13 2018-11-19 Lm Wind Power Int Tech Ii Aps A method of making an elongate composite body

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4631211A (en) * 1985-03-25 1986-12-23 Scripps Clinic & Research Foundation Means for sequential solid phase organic synthesis and methods using the same
WO1999004895A1 (en) * 1997-07-24 1999-02-04 Argonaut Technologies, Inc. Compositions for the storage and delivery of solid phase reactive particles and methods of using the same
US7338768B1 (en) * 1997-11-12 2008-03-04 Nanomics Biosystems Pty. Ltd. Carrier-reporter bead assemblies
WO2000015653A2 (en) * 1998-09-16 2000-03-23 Central Research Laboratories Limited Apparatus for, and method of, storing a plurality of chemical compounds
US20050048667A1 (en) * 2003-08-29 2005-03-03 Brett Ellman Method of forming and using solid-phase support
CN101730582A (zh) * 2007-07-03 2010-06-09 瑞典仿生3000有限公司 固相反应方法及装置
CN102271801A (zh) * 2009-01-07 2011-12-07 瑞典仿生3000有限公司 双移动相设备和方法

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
杨晓清等: "《包装机械与设备》", 31 March 2009, 国防工业出版社, pages: 158 *

Also Published As

Publication number Publication date
JP2020508203A (ja) 2020-03-19
AU2022206800A1 (en) 2022-08-18
GB201619713D0 (en) 2017-01-04
AU2022206800B2 (en) 2024-03-07
AU2017365927A1 (en) 2019-06-20
CN110234427A (zh) 2019-09-13
EP3544725A1 (en) 2019-10-02
US20190351385A1 (en) 2019-11-21
WO2018096321A1 (en) 2018-05-31
CA3043545A1 (en) 2018-05-31
US11529603B2 (en) 2022-12-20

Similar Documents

Publication Publication Date Title
US5885837A (en) Very large scale immobilized polymer synthesis using mechanically directed flow paths
WO1996016078A1 (en) Method of making a library of compounds
US20040082058A1 (en) Array hybridization apparatus and method for making uniform sample volumes
JPH11180995A (ja) 逐次固相有機合成用装置およびその使用法
WO2008051454A1 (en) Solid-phase mediated synthesis of molecular microarrays
JP2009292839A (ja) 試薬再循環を用いてオリゴマー、特に、ペプトイドを合成するための装置
EP2162208B1 (en) Solid phase reaction method and apparatus
KR101689903B1 (ko) 이중 이동상 장치 및 방법
AU2022206800B2 (en) Elongate Solid Phase Body
JP2019509167A (ja) 移動固相反応システムおよび方法
US6031074A (en) Automated Peptide design and synthesis
EP1044297A2 (en) Solid support materials
Nokihara et al. High Throughput Preparation of Peptide Arrays Containing Two Fluorescent Dyes Focusing on Practical Protein Detection Systems
US20050027100A1 (en) Solid phase immobilized trifunctional linker
US20070141724A1 (en) Solid phase immobilized trifunctional linker
US20050214930A1 (en) Apparatus and method for preventing cross contamination when dissassembling an array
Goren et al. Dendritic molecules on solid support: solid-phase synthesis and applications
US20050202445A1 (en) Thermoplastic array hybridization apparatus and method
US20050196761A1 (en) Array hybridization apparatus and method
MXPA00006077A (en) Solid support materials

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
TA01 Transfer of patent application right
TA01 Transfer of patent application right

Effective date of registration: 20231107

Address after: Leicester

Applicant after: Nova Junior Manufacturing Co.,Ltd.

Address before: Leicester

Applicant before: NOVA LABORATORY Co.,Ltd.

Effective date of registration: 20231107

Address after: Leicester

Applicant after: NOVA LABORATORY Co.,Ltd.

Address before: Norfolk, England

Applicant before: SWEDISH BIOMIMETICS 3000 Ltd.