CN115137991A - Verification die body and radiotherapy equipment - Google Patents

Abstract

The application provides a verify die body and radiotherapy equipment relates to medical instrument technical field, can carry out the verification and the registration of multiple different modes and demand to radiotherapy equipment through same verify die body, need not change the die body repeatedly, improves the accuracy of verifying and registering. The verification die body comprises a hexahedral die body, and a first marker is arranged at the geometric center of the die body; a first insertion groove and a second insertion groove are vertically formed in the die body from the first surface of the die body, the first insertion groove and the second insertion groove are perpendicularly intersected, and an intersection line of the first insertion groove and the second insertion groove is deviated from the geometric center of the die body.

Description

Verification die body and radiotherapy equipment

Technical Field

The application relates to the technical field of medical instruments, in particular to a verification die body and radiotherapy equipment.

Background

Gamma Knife (Gamma Knife) is one of the main treatment means of Stereotactic Radiosurgery, and the Gamma Knife adopts Gamma rays emitted by a cobalt-60 radioactive source, and makes the Gamma rays pass through normal tissues from all directions and focus on the target point position of focus to irradiate in a mode of rotating around an isocenter, the focused rays at the target point position have high intensity, the high-intensity Gamma rays can accurately destroy the focus at the target point position in vivo like a scalpel, and the ray intensity at the non-target point position is lower, so that the operation performed by the Gamma Knife is almost a penetrating noninvasive operation, no wound can be caused on the penetrating skin position, and the operation process is rapid, reliable and greatly reduces the operation pain of a patient.

Because the radiation intensity of the radiation used for treatment in the radiotherapy equipment at the focused treatment isocenter is high and the damage is huge, in order to effectively ensure the accuracy of the radiotherapy equipment, as an important means for treatment general evaluation, the tumor radiotherapy needs to reach four accuracies, namely: accurate positioning, accurate planning, accurate positioning and accurate treatment. Image Guided Radiation Therapy (IGRT) is an important means for improving the precision of radiation therapy and ensuring and controlling the quality of radiation therapy, and the coincidence of a mechanical rotation isocenter and a treatment isocenter is an important embodiment for ensuring the quality of radiation therapy. Meanwhile, on the premise of quality assurance, the radiotherapy equipment needs to be calibrated and calibrated; in order to verify the positioning precision before treatment, a corresponding die body is also needed to verify the positioning precision.

In the related art, the verification die body of the radiotherapy equipment has a single function, and can only be verified against one or more of the verification die bodies, so that the cost of the verification die body is high, when a plurality of verifications are needed, different verification die bodies need to be repeatedly replaced, the time consumption of the whole verification process is long, the process of the verification die body is repeatedly replaced, more secondary errors can be introduced, and the use safety and the treatment accuracy of the radiotherapy equipment are influenced.

Disclosure of Invention

An object of the embodiment of the application is to provide a verification die body and radiotherapy equipment, can carry out multiple verification to radiotherapy equipment through same verification die body, needn't change the die body repeatedly, improve the accuracy of verifying.

In one aspect of the embodiment of the application, a verification die body is provided, and includes a die body, where a first marker is arranged at a geometric center of the die body; a first insertion groove and a second insertion groove are vertically formed in the die body from the first surface of the die body, the first insertion groove and the second insertion groove are perpendicularly intersected, and an intersection line of the first insertion groove and the second insertion groove is deviated from the geometric center of the die body.

Optionally, the die body is a regular hexahedron.

Optionally, the first insertion groove is parallel to the second surface and the fourth surface of the die body, and the distance between the first insertion groove and the second surface is smaller than or equal to the distance between the first insertion groove and the fourth surface; the second insertion groove is parallel to the third surface and the fifth surface of the die body, and the distance between the second insertion groove and the third surface is smaller than or equal to the distance between the second insertion groove and the fifth surface; wherein, the distance between the first insertion groove and the second surface is equal to the distance between the second insertion groove and the third surface.

Optionally, an extraction groove is formed in the first surface of the die body, and the extraction groove is at least located at a boundary position of an opening formed in the first surface by the first insertion groove and the second insertion groove.

Optionally, the mold further comprises a first pinhole and a second pinhole which respectively penetrate through the second surface and the third surface of the mold body and vertically intersect; the first pin hole is communicated with the first insertion groove, and the second pin hole is communicated with the second insertion groove; the intersection point of the perpendicular intersection of the first pinhole and the second pinhole deviates from the geometric center of the die body.

Optionally, the verification phantom of the embodiment of the present application further includes: the first surface at the die body is provided with the connector, and the connector can be dismantled with first spliced pole and be connected, is provided with the ionization chamber probe at first spliced pole tip, and/or, the connector can be dismantled with the second spliced pole and be connected, is provided with the tungsten pearl at second spliced pole tip.

Optionally, the inner peripheral wall of the connector is formed with an internal thread, the first connecting column and the second connecting column are respectively provided with an external thread, and the first connecting column and the second connecting column are respectively in threaded connection with the connector.

Optionally, a through channel communicated with the connecting port is further provided on the die body, and the inner diameter of the through channel is smaller than or equal to that of the connecting port.

Optionally, a cross-hatch is formed in a surface of the die body.

Optionally, the cross-hatching is red cross-hatching, or the cross-hatching is white cross-hatching, or the cross-hatching is black cross-hatching.

Optionally, the validation die body of embodiments of the present application further includes a second marker disposed within the die body, the second marker being offset from a geometric center of the die body.

Optionally, the number of the second markers is at least three, the at least three second markers are distributed in the die body with the first marker as a circle center and the same preset radius, and the first markers are not coplanar with planes formed by any two second markers.

Optionally, the distance between any two second markers is equal.

Optionally, the die body is a regular hexahedron, the edge length of the die body is a, and the distance between any two second markers is equal to

Each second marker is spaced from the first marker by a distance of

Optionally, a hollow marker is further disposed in the mold body, and the hollow marker and the first marker are not coplanar with any two planes formed by the second marker.

Optionally, a strip-shaped marker is fixedly arranged on the edge of the body of the die body, which is connected with the two adjacent surfaces.

Optionally, a marking slot is also formed in at least one surface of the phantom body.

Optionally, the first surface, the second surface, the third surface and the fourth surface of the die body are respectively provided with a mark groove, and the diameters of the mark grooves formed in the first surface, the second surface, the third surface and the fourth surface are different.

Optionally, the body of the mould body is of plexiglas material.

Optionally, the die body is made of black organic glass material, or the die body is made of transparent organic glass material.

Optionally, a connecting frame for connecting with a treatment couch is connected and arranged on the die body.

Optionally, the die body is rotatably connected with the connecting frame.

Optionally, a rotation angle between the die body and the connecting frame is less than or equal to 45 °.

In another aspect of an embodiment of the present application, there is provided a radiotherapy apparatus comprising a verification phantom according to any one of the preceding claims.

According to the verification die body and the radiotherapy equipment provided by the embodiment of the application, the geometric center of the verification die body is provided with the first marker; a first insertion groove and a second insertion groove are vertically formed in the die body from the first surface of the die body, the first insertion groove and the second insertion groove are perpendicularly intersected, and an intersection line of the first insertion groove and the second insertion groove is deviated from the geometric center of the die body. Adopt the verification die body of this application embodiment to carry out calibration verification to radiotherapy equipment, owing to be provided with the first marker as the center on the die body, can carry out mechanical calibration and isocenter and geometric parameters to radiotherapy equipment and mark, verify the precision of image guide and verify nuclear physics isocenter, consequently this verification die body can a plurality of verification functions of realization, for only can realize the verification die body of single function in the correlation technique, the function of the verification die body that this application embodiment provided is more abundant.

Drawings

To more clearly illustrate the technical solutions of the embodiments of the present application, the drawings that are required to be used in the embodiments of the present application will be briefly described below, it should be understood that the following drawings only illustrate some embodiments of the present application and therefore should not be considered as limiting the scope, and that those skilled in the art can also obtain other related drawings based on the drawings without inventive efforts.

Fig. 1 is a schematic structural diagram of a verification mold according to an embodiment of the present disclosure;

FIG. 2 is a second schematic view illustrating a structure of a verification mold according to an embodiment of the present disclosure;

fig. 3 is a third schematic structural diagram of a verification phantom according to an embodiment of the present disclosure;

FIG. 4 is a fourth schematic view illustrating a structure of a verification mold according to an embodiment of the present disclosure;

fig. 5 is a fifth schematic view illustrating a structure of a verification mold according to an embodiment of the present application;

FIG. 6 is a sixth schematic view of a structure of a verification mold body according to an embodiment of the present application;

fig. 7 is a seventh schematic structural diagram of a verification mold according to an embodiment of the present disclosure.

Icon: 10-a die body; 101-a first surface; 1011-connecting port; 102-a second surface; 103-a third surface; 104-a fourth surface; 105-a fifth surface; 11-a first label; 12-a second label; 13-a hollow marker; 21-a first insertion slot; 22-second insertion slot; 31-a first pinhole; 32-second pinhole; 40-a first connecting column; 41-ionization chamber probe; 50-a second connecting column; 51-tungsten beads; 60-a connecting frame; 70-extracting the groove; 80-a through channel; 90-cross-hatching.

Detailed Description

The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application.

In the description of the present application, it should be noted that the terms "inside", "outside", and the like indicate orientations or positional relationships based on orientations or positional relationships shown in the drawings or orientations or positional relationships that the product of the application is usually placed in when used, and are used only for convenience of description and simplification of the description, but do not indicate or imply that the device or element referred to must have a specific orientation, be constructed in a specific orientation, and operate, and thus, should not be construed as limiting the present application. Furthermore, the terms "first," "second," and the like are used solely to distinguish one from another, and are not to be construed as indicating or implying relative importance.

It should also be noted that, unless expressly stated or limited otherwise, the terms "disposed" and "connected" are to be construed broadly, e.g., as meaning fixedly connected, detachably connected, or integrally connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meaning of the above terms in the present application can be understood in a specific case by those of ordinary skill in the art.

With the progress of the times, the living standard of people is higher and higher, but the probability of cancer is higher and higher due to poor living habits and pollution of living environment. In the current medical treatment means, the treatment modes for cancer and tumor include three treatment directions of surgery, chemotherapy and radiotherapy.

Radiotherapy, also called radiotherapy, refers to a method of local treatment of tumors by using radiation, and compared with surgery which requires that patients have severe physical conditions capable of performing surgery and physical damage caused by indiscriminate attack of chemotherapy on all cells in the body of the patients, about 70% of cancer patients need to adopt and actively select radiotherapy in the process of treating cancer, and treatment data shows that about 40% of cancers can be radically treated by using radiotherapy. The role and position of radiotherapy in tumor treatment are increasingly prominent, and the radiotherapy has become one of the main means for treating malignant tumors. Especially with the progress of development of medical devices in recent years, the radiotherapy technology has now progressed from two-dimensional radiotherapy to three-dimensional radiotherapy, four-dimensional radiotherapy, radiotherapy dose distribution has also progressed from point dose to volume dose distribution, and dose intensification in volume dose distribution. Taking a common gamma knife of radiotherapy equipment as an example, the gamma knife belongs to stereotactic radiotherapy equipment, which requires accurate space stereotactic positioning precision, and requires that the dose of radioactive rays outside a target region is attenuated quickly, and the like, and the requirements are to ensure the tumor treatment effect in the target region and reduce the adverse effects on other good parts of a body while the tumor treatment effect is ensured by adopting the gamma knife.

The following description will be made in detail with reference to a gamma knife as an example, and a radiotherapy device and a treatment process using the radiotherapy device.

The gamma knife comprises a working host and a three-dimensional treatment bed at least partially extending into the working host. Taking the gamma knife device for head treatment as an example, the front end (the part for bearing and fixing the head of a patient) of the treatment couch extends into a main machine, the main machine is of a hemispherical structure, a radioactive source is arranged in the hemispherical structure of the main machine under multiple shielding protection, and the radioactive source emits beams towards the direction of a target area and focuses on the target point under the shielding-cancelled state (namely, the open source state). In the actual operation process of the gamma knife, in order to avoid the situation that the skin at a certain fixed position of the skin of a human body is burnt due to the fact that the radiation source is driven by the main machine to rotate at a constant speed, the radiation source can rotate at the mechanical isocenter of radiotherapy equipment, the situation that the radiation beam always penetrates through a fixed position or a small fixed area on the skin to focus on a target point is avoided, and therefore other healthy parts of a patient are protected from being damaged by the radiation beam with high intensity to the maximum extent.

However, due to the reasons of installation and debugging of the device, repeated operation in the using process, and the like, it is often difficult to ensure that the mechanical rotation isocenter of the main machine coincides with the treatment isocenter, and if the mechanical rotation isocenter and the treatment isocenter cannot coincide, it is impossible to ensure that high-intensity rays are focused on the target point for treatment, and the center of the beam is usually provided with ultrahigh ray intensity for treating or cutting an affected part, and body tissues exposed to the ultrahigh ray intensity are seriously damaged, so for the accuracy of treatment and the safety of a patient, it is necessary to perform geometric calibration on the radiotherapy device and the verification of the deviation of the mechanical rotation isocenter and the treatment isocenter in various ways before treatment, guide the positioning accuracy by verifying an image, and calibrate the geometric parameters of the radiotherapy device.

The embodiment of the application provides a verification die body, fig. 1 is one of schematic structural diagrams of the verification die body in the embodiment of the application, and as shown in fig. 1, the verification die body includes a hexahedral die body 10, the die body 10 is a solid die body, and a first marker 11 is arranged at a geometric center of the die body 10; a first insertion groove 21 and a second insertion groove 22 are vertically formed in the first surface 101 of the die body 10 toward the die body 10, the first insertion groove 21 and the second insertion groove 22 vertically intersect in the die body 10, and an intersection line where the first insertion groove 21 and the second insertion groove 22 vertically intersect deviates from a geometric center of the die body 10.

According to the verification die body provided by the embodiment of the application, the geometric center of the die body 10 is provided with the first marker 11 serving as the center, the mechanical isocenter of radiotherapy equipment can be calibrated through the first marker 11, and after the mechanical isocenter is calibrated, the IGRT system can be geometrically calibrated, for example, the offset of a flat plate and a bulb tube is calibrated, the distance from the bulb tube to the flat plate is calibrated, and the distance from the bulb tube to a rotating shaft is calibrated. In addition, the vertical first insertion groove 21 and the vertical second insertion groove 22 which are arranged on the die body 10, the focal spot is formed in the center of the film after the film is printed by the beam of the radioactive source through the film which is respectively inserted into the first insertion groove 21 and the second insertion groove 22, and the deviation of the coordinate of the nuclear physics isocenter (namely the beam focus of the radioactive source) can be determined through analyzing the center of the focal spot, so that whether the nuclear physics isocenter is coincided with the mechanical isocenter of the radiotherapy equipment or not is verified.

To sum up, the verification die body of this application embodiment can be integrative carry out the calibration of mechanical isocenter, carry out the deviation of geometric calibration, physics isocenter to the IGRT system and verify etc. consequently, this verification die body can be integrative realizes multiple verification function, for only can realize the verification die body of single function among the correlation technique, the function of the verification die body that this application embodiment provided is more abundant.

Optionally, as shown in fig. 1, the mold body 10 may be a regular hexahedron, that is, a cubic structure, that is, each surface of the mold body 10 is a square, so that it is convenient to verify the overall structure design of the mold body, and the first marker 11 is disposed in the regular hexahedron, so that the distances between each surface of the regular hexahedron and the first marker 11 are equal, and thus, the geometric parameters of the radiotherapy apparatus can be more accurately detected in the three-dimensional space, and the accuracy of image-guided positioning is improved. Hereinafter, all the description and the drawings are explained with the mold body 10 being a regular hexahedron.

Alternatively, as shown in fig. 1, the first insertion groove 21 is parallel to the second surface 102 and the fourth surface 104 of the die body 10, and the distance between the first insertion groove 21 and the second surface 102 is smaller than or equal to the distance between the first insertion groove 21 and the fourth surface 104; the second insertion groove 22 is parallel to the third surface 103 and the fifth surface 105 of the die body 10, and the distance between the second insertion groove 22 and the third surface 103 is smaller than or equal to the distance between the second insertion groove 22 and the fifth surface 105; wherein, the distance between the first insertion groove 21 and the second surface 102 is equal to the distance between the second insertion groove 22 and the third surface 103.

In order to avoid interference between the first and second insert pockets 21 and 22 and the first marker 11, an intersection line at which the first and second insert pockets 21 and 22 perpendicularly intersect is offset from a geometric center of the mold body 10, the second and fourth surfaces 102 and 104 of the mold body 10 are opposite surfaces of the mold body 10, the first insert pocket 21 is disposed parallel to the second surface 102, the first insert pocket 21 is disposed relatively close to the second surface 102, and similarly, the third and fifth surfaces 103 and 105 of the mold body 10 are opposite surfaces of the mold body 10, the second insert pocket 22 is disposed parallel to the third surface 103, the second insert pocket 22 is disposed relatively close to the third surface 103, and the distance between the first insert pocket 21 and the second surface 102 is equal to the distance between the second insert pocket 22 and the third surface 103. When the film inserted into the first insertion groove 21 is irradiated by the radiation source, irradiation can be performed in the direction from the second surface 102 or the fourth surface 104, or irradiation can be performed in a manner of rotating to pass through the second surface 102, the third surface 103, the fourth surface 104 and the fifth surface 105 in sequence, so that other external influences are avoided as much as possible during the comparison analysis of the subsequent scanned image and the image, and the accuracy of the comparison analysis is improved.

Alternatively, as shown in fig. 1, an extraction groove 70 is formed on the first surface 101 of the mold body 10, and the extraction groove 70 is located at least at a boundary position of the openings formed on the first surface 101 by the first insertion groove 21 and the second insertion groove 22.

In the embodiment of the present application, as shown in fig. 1, the film inserted into the first insertion slot 21 or the second insertion slot 22 is generally subjected to a pre-dimensional cutting matching, so that the film is inserted into the first insertion slot 21 or the second insertion slot 22 in a shape matching and position stabilization manner, so as to verify the reliability of the treatment isocenter and the mechanical rotation isocenter. When the film needs to be taken out after physical filming is checked, it is often difficult to form an accurate hand grip on the verification mold body, therefore, the first surface 101 of the mold body 10 is provided with the extraction groove 70, the extraction groove 70 is formed by being recessed toward the inside of the mold body 10, and the extraction groove 70 is at least located at the boundary position of the openings formed on the first surface 101 by the first insertion groove 21 and the second insertion groove 22, so that the film inserted into the first insertion groove 21 and the film inserted into the second insertion groove 22 can be exposed only by one extraction groove 70.

In the embodiment of the present application, the shape, depth, and the like of the extraction groove 70 are not particularly limited as long as a structure for facilitating positioning and extraction after inserting the film is formed on the first surface 101 at the extraction positions corresponding to the first insertion groove 21 and the second insertion groove 22, for example, the extraction groove 70 may be a rectangular groove, an arc groove, and the like. In addition, the inserted film is not particularly limited in the embodiment of the present application, for example, the inserted film may be a self-developing disposable film, and the size of the film may be matched with the size of the first insertion slot 21 or the second insertion slot 22, or the shape of the film may be matched with the overall shape of the first insertion slot 21 and the second insertion slot 22, and the film may be a single film composed of two sub-films perpendicular to each other and intersecting each other.

Optionally, as shown in fig. 1, further comprises a first pinhole 31 and a second pinhole 32 which respectively penetrate through the second surface 102 and the third surface 103 of the die body 10 and perpendicularly intersect; the first needle hole 31 communicates with the first insertion groove 21, and the second needle hole 32 communicates with the second insertion groove 22. Optionally, the intersection of the perpendicular intersection of the first and second bores 31, 32 is offset from the geometric centre of the phantom body 10.

In the verification of the deviation of the physical isocenter of the film inserted into the first insertion slot 21 or the second insertion slot 22, after the film is printed by the radiation source, it is necessary to prick the film inserted into the first insertion slot 21 or the second insertion slot 22 according to a point calculated in advance to form a reference position mark, which is a theoretical focal center of the mark, for example, a first pin hole 31 is provided on the second surface 102 penetrating the die body 10, a second pin hole 32 is provided on the third surface 103 penetrating the die body 10, aperture passages of the first pin hole 31 and the second pin hole 32 are perpendicularly intersected, and the first pin hole 31 is communicated with the first insertion slot 21, a prick or a marker inserted through the first pin hole 31 can directly form the reference position mark on the film inserted into the first insertion slot 21, and similarly, the second pin hole 32 is communicated with the second insertion slot 22, and a prick or a marker inserted through the second pin hole 32 can directly form the reference position mark on the film inserted into the second insertion slot 22. And then the actual central point of the focal spot in the two films, namely the actual nuclear physics isocenter, is obtained through the analysis of the scanner, and because the central point of the verification die body (namely the center of the first marker 11) is superposed with the mechanical rotation isocenter, the reference position mark on the film can be used as the theoretical nuclear physics isocenter, so that the deviation between the actual nuclear physics isocenter and the theoretical nuclear physics isocenter can be verified through the reference position mark, and the precision and the efficiency of determining the deviation are improved.

It should be noted that, in the embodiment of the present application, it is not limited that the first needle hole 31 and the second needle hole 32 must be penetrated by the second surface 102 and the third surface 103 of the die body 10, and it is to be ensured that the bore passages of the first needle hole 31 and the second needle hole 32 intersect perpendicularly as long as the penetrating surfaces of the first needle hole 31 and the second needle hole 32 are adjacent surfaces on the die body 10. Taking the first needle hole 31 as an example, the first needle hole 31 may also be a through hole penetrating through the second surface 102 of the die body 10 and penetrating through the opposite fourth surface 104, so that an operator can flexibly select to mark the film by the second surface 102 or the fourth surface 104 when performing the needle punching marking. When the first insertion groove 21 is parallel to the second surface 102 and the fourth surface 104 of the die body 10, the distance between the first insertion groove 21 and the second surface 102 is less than or equal to the distance between the first insertion groove 21 and the fourth surface 104; the second insertion groove 22 is parallel to the third surface 103 and the fifth surface 105 of the die body 10, and the distance between the second insertion groove 22 and the third surface 103 is smaller than or equal to the distance between the second insertion groove 22 and the fifth surface 105; moreover, when the distance between the first insertion groove 21 and the second surface 102 is equal to the distance between the second insertion groove 22 and the third surface 103, the first pinhole 31 penetrates through the second surface 102 of the die body 10, and the second pinhole 32 penetrates through the third surface 103 of the die body 10, on one hand, when the film is respectively pricked and marked through the first pinhole 31 and the second pinhole 32, the penetration depth is as small as possible, and the penetration depths of the first pinhole 31 and the second pinhole 32 are equal, thereby facilitating the operation and reducing the operation error in the marking operation as much as possible.

Optionally, the verification phantom of the embodiment of the present application further includes: first connecting post 40 and/or second connecting post 50; as shown in fig. 3, a connection port 1011 is provided on the first surface 101 of the mold body 10, and as shown in fig. 2, the connection port 1011 is detachably connected to the first connection column 40, and an ionization chamber probe 41 is provided at an end of the first connection column 40; alternatively, as shown in fig. 4, the connection port 1011 can be detachably connected to the second connection post 50, and the end of the second connection post 50 is provided with a tungsten bead 51.

For example, as shown in fig. 2, the connection port 1011 disposed on the first surface 101 of the phantom body 10 may be used to detachably connect and dispose the first connection column 40, and the ionization chamber probe 41 is disposed at the end of the first connection column 40, and the ionization chamber probe 41 may be used to detect and verify the radiation dose at a preset position, for example, a treatment focus position (treatment isocenter), so as to determine whether the radiation dose at the preset position is within a range required by a theoretical dose value.

Optionally, as shown in fig. 4, the connection ports 1011 formed on the first surface 101 of the die body 10 may also be used to detachably connect the second connection post 50, and the tungsten beads 51 are formed at the end of the second connection post 50. When the verification phantom of the embodiment of the application is used, the tungsten bead 51 may be set at a mechanical isocenter, the tungsten bead 51 is irradiated by a radiation source at different angles, projection data is acquired from a detector, such as an EPID flat plate or an EPID detector, which is disposed opposite to the radiation source, and an image is generated, and deviation verification is performed on the mechanical isocenter and a treatment isocenter by analyzing a light spot center and a shadow center in the image acquired by the EPID flat plate or the EPID detector.

In addition, in order to avoid the thickness difference of the entity structure that the ray irradiation of all directions passed through to tungsten pearl 51, the inconsistent problem of the attenuation degree of the ray of all directions when leading to formation of image, also can set up second spliced pole 50 and be inside cavity to avoid because the ray attenuation degree is inconsistent when irradiating tungsten pearl 51 department to the ray of all directions when forming of image, the image brightness that leads to is inhomogeneous, the comparatively difficult problem during later stage analysis image.

Optionally, an internal thread is formed on the inner peripheral wall of the connection port 1011, external threads are respectively provided on the first connection column 40 and the second connection column 50, and the first connection column 40 and the second connection column 50 are respectively in threaded connection with the connection port 1011. Adopt this kind of mode detachable replacement to set up first spliced pole 40 or second spliced pole 50, it is all comparatively convenient to dismantle with the installation, and can guarantee the fastness and the accuracy of connecting after connecting.

Optionally, as shown in fig. 3, a through channel 80 communicating with the connection port 1011 is further provided on the die body 10, and an inner diameter of the through channel 80 is equal to or smaller than an inner diameter of the connection port 1011. When the inner diameter of the through channel 80 is equal to the inner diameter of the connection port 1011, and the first connection column 40 or the second connection column 50 is detachably mounted on the connection port 1011, the position relationship between the first connection column 40 or the second connection column 50 and the die body 10 can be adjusted through the through channel 80. When the inner diameter of the through channel 80 is smaller than the inner diameter of the connection port 1011, the convenience of mounting and dismounting can be ensured, and the connection structure can be mounted in the through channel 80 in time.

It should be noted that the ionization chamber is a detector for measuring ionizing radiation by using ionization effect of ionizing radiation, which is also called as an ionization chamber, the ionization chamber probe 41 needs to be connected with a measurement result display device through a wire, so as to make the detection of radiation dose easier to implement and set on the verification die body, and if the wire is exposed to a large dose of radiation environment, the wire is also easily damaged, therefore, a through channel 80 can be provided in the die body 10, and meanwhile, the first connection column 40 is also provided with a hollow interior, so as shown in fig. 3, when the ionization chamber probe 41 is provided, the ionization chamber probe 41 can be directly sent to the end of the first connection column 40 connected to the connector 1011 through the through channel 80 from the rear portion of the die body, thereby avoiding the wire from being wound in the radiotherapy device, and also avoiding the wire from being damaged due to being exposed to the large dose of radiation environment.

Optionally, as shown in fig. 1, a cross-hatch 90 is formed on the surface of the mold body 10.

The cross-shaped scribe lines 90 are formed on at least three surfaces (for example, the second surface 102, the third surface 103, and the fifth surface 105) of the die body 10, and the cross center of the cross-shaped scribe line 90 on each surface is set as the target point position of the side surface, so that the position of the die body 10 can be adjusted to make the cross-shaped scribe line 90 on each side surface coincide with the cross-shaped laser line emitted by the laser lamp, thereby realizing the positioning of the verification die body.

Optionally, cross score 90 is a red cross score, alternatively, cross score 90 is a white cross score, alternatively, cross score 90 is a black cross score.

The cross-shaped scribe lines 90 arranged on the surface of the die body 10 can be red cross-shaped scribe lines, white cross-shaped scribe lines or black cross-shaped scribe lines, the red cross-shaped scribe lines, the white cross-shaped scribe lines or the black cross-shaped scribe lines are displayed on the surface of the die body 10 clearly, and alignment operation of cross-shaped rays emitted by a laser lamp and the red cross-shaped scribe lines, the white cross-shaped scribe lines or the black cross-shaped scribe lines is facilitated.

Optionally, as shown in fig. 5, the verification phantom of the embodiment of the present application further includes a second marker 12 disposed within the phantom body 10, the second marker 12 being offset from the geometric center of the phantom body 10.

Optionally, as shown in fig. 5, the number of the second markers 12 is at least three, and four in fig. 5, the at least three second markers 12 are distributed in the mold body 10 with the first marker 11 as a center of a circle and with the same preset radius, and the first markers 11 are not coplanar with planes formed by any two second markers 12. The distance between any two second markers 12 is equal.

The die body 10 is of a regular hexahedral structure, the first markers 11 are arranged at the geometric center of the die body 10, the distance between each second marker 12 and the first marker 11 is equal, the second markers 12 are arranged in different directions of the first marker 11 by the same preset radius, the first marker 11 and any two second markers 12 can form a plane, planes formed by different second markers 12 are not coplanar, and for example, at least three second markers 12 can be respectively arranged in the directions of X, Y and Z in a three-dimensional coordinate system taking the die body 10 as the center.

Optionally, the die body 10 is a regular hexahedron, the length of the die body 10 is a, and the distance between any two second markers 12 is equal to the length of the die body 10

Each second marker 12 is spaced from the first marker 11 by a distance of

The gamma knife is divided into a head gamma knife and a body gamma knife according to different treatment areas of the body of a patient, in general, the target area of the head gamma knife is a spherical area of 50mm, the target area of the body gamma knife is a spherical area of 100mm, the die body 10 is arranged to be a cube with the edge length a equal to 60mm, and the linear distance between any two second markers 12 is equal to the edge length a of the die body 10 and is also equal to the edge length a of the die body 10

Furthermore, each second marker 12 is linearly distanced from the first marker 11 by

Also is that

In this way, on one hand, a fixed mutual relationship is formed between each second marker 12 and the first marker 11, so that the processing and preparation of the first marker 11 and the second marker 12 in the die body 10 can be carried out according to the mutual relationship, and the setting precision is easy to control, on the other hand, the verification die body of the die body 10 with a cubic structure and the edge length of 60mm can meet the image guide positioning of the body gamma knife in a spherical area with the target area of 100mm, and can also be used for the image guide positioning of the head gamma knife in a spherical area with the target area of 50mm, the space in the gamma knife main machine can be fully utilized, and the method is applicable to the verification of the head gamma knife and the body gamma knife.

In order to avoid adverse effects of the first marker 11 and the second marker 12 on radiotherapy, materials having a density similar to the density of human bones are generally selected for the first marker 11 and the second marker 12. Illustratively, at least one of aluminum, teflon, glass, or ceramic may be employed. Moreover, the first marker 11 and the second marker 12 are each a small spherical structure for easy arrangement and identification of imaging.

Optionally, as shown in fig. 5, hollow markers 13 are further disposed in the phantom body 10, and the hollow markers 13 are not coplanar with the first markers 11 and the planes formed by any two second markers 12.

The hollow sphere is filled with air, other special gases do not need to be separately filled, the beam irradiates the verification mold body of the embodiment of the present application, the hollow marker 13 appears as a light spot in an image received by the detector, and particularly when the mold body 10 is a cube, in the verification process of placing the verification mold body on a treatment couch, because each surface of the verification mold body is not clearly distinguished from the appearance, the orientation of each surface of the verification mold body is often easily confused, and the setting position of the hollow marker 13 is determined in advance (the hollow marker 13 is not located at the geometric center of the cube, for example, the hollow marker 13 may be located at a side close to the first surface 101 of the mold body 10), so that the head and foot directions of the verification mold body placed on the treatment couch can be accurately and quickly determined by determining the position of the light spot in the image received by the detector.

Moreover, the planes formed by the hollow markers 13 and the first markers 11 and any two second markers 12 are not coplanar, that is, the arrangement of the hollow markers 13 in the phantom body 10 meets the requirement of the arrangement condition of the second markers 12, so that when geometric calibration is performed by verifying the phantom, the hollow markers 13 can also be used as the second markers 12 to represent deviations in the formed image, and the larger the number of the second markers 12, the more dimensionality is provided for representing the deviations in the formed image, and the more abundant identification data and registration information are provided for the deviations.

Optionally, a strip-shaped marker is fixedly arranged on an edge of the die body 10 where two adjacent surfaces are connected. For another example, a mark groove having a cross-sectional shape of an axisymmetric pattern or a centrosymmetric pattern is further formed on the first surface 101 of the mold body 10.

The strip-shaped markers are fixedly arranged on the lateral edges of the die body 10, for example, aluminum strips fixed on the lateral edges by means of adhesion, and the first surface 101 of the die body 10 may further be provided with marking grooves, the cross-sectional shapes of which are axisymmetric or centrosymmetric, for example, the marking grooves are rectangular grooves, triangular grooves, or the like. When various marking structures are arranged on the die body 10, after being received by a detector, the ray irradiates the verification die body and is transmitted to a plurality of multi-angle image analysis in an image server, the various marking structures can be correspondingly displayed in the image, so that the verification die body of the embodiment of the application can enrich verification information of a treatment center point and a mechanical rotation isocenter of radiotherapy equipment through various marking characteristics, and the verification accuracy is further improved.

As shown in fig. 6, the mark groove may be configured as an annular groove, and the annular grooves disposed on four different surfaces (the second surface 102, the third surface 103, the fourth surface 104, and the fifth surface 105) of the mold body 10 may be configured as different sizes, wherein the upper surface (the second surface 102) corresponds to the lower surface (the fourth surface 104), and the diameter of the annular groove on the upper surface of the mold body 10 is smaller than that of the annular groove on the lower surface, wherein when the annular groove is a circular ring as shown in fig. 6, the width and the depth of the circular ring are preset, and the disposed annular groove and the first marker 11, the second marker 12, the hollow marker 13, and the tungsten bead 51 in the mold body 10 are mutually positionally deviated, so that, when the verification mold body of the embodiment of the present application is used for geometric calibration, on one hand, the registration information of the deviation can be increased and more abundant in the formed image, on the other hand, by setting the annular grooves with different sizes, the direction and the placement state of the verification phantom can be intuitively judged when the image is formed, and similarly, the diameter of the annular groove on the left surface (the third surface 103) of the phantom body 10 is smaller than that of the annular groove on the right surface (the fifth surface 105), wherein when the annular groove is in a circular ring shape as shown in fig. 6, the width and the depth of the circular ring are preset, and the arranged annular groove and the first marker 11, the second marker 12, the hollow marker 13 and the tungsten bead 51 in the phantom body 10 are mutually arranged and avoided, so that two pairs of annular grooves with different sizes are oppositely arranged in six outer side surfaces of the phantom body 10 in pairs, and the two opposite surfaces (the first surface 101 and the back surface opposite to the first surface 101) are not provided with the annular grooves, so that an operator can visually and accurately recognize the setting position and the setting state of the verification die body in the radiotherapy equipment through images conveniently according to the setting structures.

Optionally, the mould body 10 is of plexiglas material. Illustratively, the mold body 10 is made of black organic glass material, or the mold body 10 is made of transparent organic glass material.

The die body 10 is made of organic glass material, and the organic glass material has better permeability for laser rays and beams emitted by the radioactive source, so that the transmission and imaging of the laser rays or the beams of the radioactive source cannot be influenced. In an example, the die body 10 may be made of black organic glass material, or the die body 10 may be made of transparent organic glass material, the die body 10 made of transparent organic glass material is transparent, and the structures such as the first marker 11, the second marker 12, the first insertion groove 21, the second insertion groove 22 and the like in the die body 10 can be clearly and visually seen, so that the setting of the die body during use is convenient to verify.

Optionally, as shown in fig. 7, a connecting frame 60 for connecting with a treatment couch is connected to the mold body 10.

On this basis, the connecting frame 60 can be provided as a rotatable mounting structure, so that through adjustment of the connecting frame 60, the phantom body 10 can be rotationally adjusted with respect to a treatment bed or other mounting positions, and the adjustment angle can be set within 45 °.

For different radiotherapy equipment, the equipment structure of the radiotherapy equipment and the placement requirements of the verification die body are different, in order to fix the verification die body on the radiotherapy equipment and enable the verification die body to be installed on different radiotherapy equipment in a matching mode as adaptive as possible, the connecting frame 60 is connected and arranged on the surface of one side, away from the first surface 101, of the die body 10, and the connecting frame 60 is connected with a treatment bed of the radiotherapy equipment.

Still taking the gamma knife as an example, when the verification die body of the embodiment of the present application is applied to the head gamma knife, the U-shaped frame at the treatment bed fixing position of the head gamma knife is connected to the connecting frame 60, so that the verification die body of the embodiment of the present application is fixed to the treatment bed of the head gamma knife. When the verification phantom body of the embodiment of the present application is applied to a body gamma knife, a bottom plate is connected to the connecting frame 60, and the verification phantom body of the embodiment of the present application is placed on a treatment couch through the bottom plate. In this way, by the arrangement of the connecting frame 60, on the basis of not damaging and influencing the verification phantom of the embodiment of the present application, the verification phantom of the embodiment of the present application can be applied to verification, registration and positioning of various radiotherapy devices, and the universality of the verification phantom of the embodiment of the present application in radiotherapy devices of various types, models and treatment positions is improved.

In another aspect of an embodiment of the present application, there is provided a radiotherapy apparatus comprising a verification phantom according to any one of the preceding claims.

Radiotherapy equipment for performing radiotherapy on a target area at an affected part determined by a patient generally includes a main machine provided with a radiation source, and a treatment couch for lying and fixing the patient. Before the radiotherapy is carried out on a patient, the verification die body is required to carry out verification work such as deviation verification between a mechanical rotation isocenter and a target point of ray focusing, geometric parameter calibration, image guide positioning precision verification and the like on the radiotherapy equipment so as to ensure the radiotherapy precision during treatment. According to the requirement of precision verification, the radiotherapy device can also comprise a detector for acquiring images, wherein the detector is used for acquiring images irradiated by a radioactive source and images irradiated by a bulb tube, and on the basis, the radiotherapy device can also comprise components for assisting control, analysis and calculation, such as a host, a server and the like.

When the radiotherapy equipment further comprises a controller and a server, images obtained in the verification processes and the geometric calibration can be sent to the server for analysis and processing, and the positioning data obtained by analysis can be stored in the controller and used for analyzing the long-term accuracy and error conditions of the equipment and the like. And after the work of deviation verification, geometric parameter calibration, guiding positioning and the like is finished, the formulated treatment program can be stored in the controller, and the control and monitoring of the treatment process can be carried out through the controller.

The radiotherapy device provided by the embodiment of the application comprises the verification phantom in any one of the above. The utility model discloses a film core physical filming method, including the steps of adopting a verification die body to carry out registration verification on radiotherapy equipment, wherein the die body 10 is of a hexahedral solid structure, as a first marker 11 is arranged at the geometric center of the die body 10, geometric calibration can be carried out on the radiotherapy equipment, the deviation between a mechanical rotation isocenter and a treatment isocenter of ray focusing in the radiotherapy equipment is verified, a first insertion groove 21 and a second insertion groove 22 which are perpendicular to each other are arranged on the die body 10 and are respectively used for inserting films, the films core physical filming inserted into the first insertion groove 21 and the second insertion groove 22 forms a focal spot at the center of the films, and the deviation of the coordinates of the core physical isocenter can be calculated by verifying the coincidence condition or the space difference of the focal spot center and a preset focal spot in the films. The radiotherapy equipment of this application embodiment can send the ray through radiation and bulb to receive through the detector and see through the image of verifying the die body, thereby carry out the deviation between mechanical rotation isocenter and treatment isocenter to radiotherapy equipment and verify, mark geometric parameters and verify the precision that the image guide was put in position, this verifies the die body and can integratively realize more verification function to radiotherapy equipment, and the function is abundanter.

In the foregoing description of the verification phantom, the structure and operation of various verifications performed on the radiotherapy device by using the verification phantom have been described in detail, and are not described herein again.

The above description is only an example of the present application and is not intended to limit the scope of the present application, and various modifications and changes may be made by those skilled in the art. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present application shall be included in the protection scope of the present application.

Claims (20)

1. A verification die body is characterized by comprising a die body, wherein a first marker is arranged at the geometric center of the die body; a first insertion groove and a second insertion groove are vertically formed in the die body from the first surface of the die body to the inside of the die body, the first insertion groove and the second insertion groove are perpendicularly intersected, and an intersection line of the first insertion groove and the second insertion groove which are perpendicularly intersected deviates from the geometric center of the die body.

2. A verification phantom according to claim 1, wherein said phantom body is a regular hexahedron.

3. The validation die body of claim 1, wherein the first insertion slot is parallel to the second and fourth surfaces of the die body, the first insertion slot being spaced from the second surface by a distance less than or equal to a distance between the first insertion slot and the fourth surface; the second insertion groove is parallel to a third surface and a fifth surface of the die body, and the distance between the second insertion groove and the third surface is smaller than or equal to the distance between the second insertion groove and the fifth surface; wherein a distance between the first insertion groove and the second surface is equal to a distance between the second insertion groove and the third surface.

4. The verification die body according to any one of claims 1 to 3, wherein an extraction groove is formed on the first surface of the die body, and the extraction groove is at least located at a junction position of openings formed in the first surface of the first insertion groove and the second insertion groove.

5. The validation die body of any of claims 1-3, further comprising first and second pin holes passing through and perpendicularly intersecting the second and third surfaces, respectively, of the die body; the first pin hole is communicated with the first insertion groove, and the second pin hole is communicated with the second insertion groove; and the intersection point of the vertical intersection of the first pinhole and the second pinhole deviates from the geometric center of the die body.

6. The verification phantom according to any one of claims 1 to 3, wherein a connection port is provided on the first surface of the phantom body, said connection port being detachably connectable to a first connection post, an ionization chamber probe being provided at the end of said first connection post; and/or the presence of a gas in the atmosphere,

the connector can be detachably connected with the second connecting column, and the end part of the second connecting column is provided with tungsten beads.

7. A verification phantom according to any of claims 1 to 3, wherein cross-hatching is formed in the surface of the phantom body.

8. The authentication phantom according to any of claims 1 to 3, further comprising a second marker disposed within the phantom body, the second marker being offset from the geometric center of the phantom body.

9. The verification phantom according to claim 8, wherein the second markers include at least three second markers, at least three second markers are distributed in the phantom body with the same predetermined radius around the first marker, and the first markers are not coplanar with planes formed by any two second markers.

10. A verification phantom according to claim 9, wherein the distance between any two of said second markers is equal.

11. A verification mould body according to claim 9, wherein said mould body is a regular hexahedron, the edge length of said mould body is a, and the distance between any two of said second markers is equal to

Each of the second markers is spaced from the first marker by a distance of

12. A verification phantom according to claim 9, further provided with hollow markers within the phantom body, said hollow markers being non-coplanar with the plane respectively defined by said first marker and any two second markers.

13. A verification mould body as claimed in any one of claims 1 to 3, wherein a strip-shaped marker is fixedly arranged on the edge of the body of the mould body where two adjacent surfaces are connected.

14. A verification phantom according to any of claims 1 to 3, wherein a marking slot is also formed in at least one surface of the phantom body.

15. A verification phantom according to claim 14, wherein said first, second, third and fourth surfaces of said phantom body are provided with respective marking grooves, and the diameters of said marking grooves provided on said first, second, third and fourth surfaces are different.

16. A verification phantom according to any of claims 1 to 3, wherein said phantom body is of plexiglas material.

17. The verification phantom according to any one of claims 1 to 3, wherein a connection frame for connecting with a treatment bed is connected to the phantom body.

18. A verification phantom according to claim 17, wherein said phantom body is pivotally connected to said attachment frame.

19. A verification phantom according to claim 18, wherein the angle of rotation between said phantom body and said attachment frame is less than or equal to 45 °.

20. A radiotherapy apparatus comprising a verification phantom according to any of claims 1 to 19.

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