CN115137912A - Automatic infusion device for PET-CT radioactive drugs - Google Patents
Automatic infusion device for PET-CT radioactive drugs Download PDFInfo
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- CN115137912A CN115137912A CN202211065887.3A CN202211065887A CN115137912A CN 115137912 A CN115137912 A CN 115137912A CN 202211065887 A CN202211065887 A CN 202211065887A CN 115137912 A CN115137912 A CN 115137912A
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- liquid mixing
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2048—Connecting means
- A61J1/2051—Connecting means having tap means, e.g. tap means activated by sliding
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/007—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests for contrast media
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14212—Pumping with an aspiration and an expulsion action
- A61M5/14228—Pumping with an aspiration and an expulsion action with linear peristaltic action, i.e. comprising at least three pressurising members or a helical member
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
Abstract
The invention belongs to the technical field of medical instruments, and particularly relates to a PET-CT radioactive drug automatic infusion device which comprises a radiation-proof box body, wherein a partition plate for dividing an inner cavity of the radiation-proof box body into a storage cavity and a liquid mixing cavity is integrally formed in the radiation-proof box body, a normal saline storage tank and a radioactive drug storage tank are placed in the storage cavity, a liquid mixing barrel and a siphon module are fixedly installed in the liquid mixing cavity, the siphon module is arranged between the storage cavity and the liquid mixing cavity, and a pumping module is arranged in the liquid mixing barrel. The invention can reduce the use of various sensors, reduce the equipment failure caused by the damage of electrical elements, avoid setting a complicated control system, and has better stability compared with the conventional manual control or control system control design. Meanwhile, the required medicine amount can be determined according to the physical condition of the patient, and more accurate injection amount is realized.
Description
Technical Field
The invention belongs to the technical field of medical instruments, and particularly relates to a PET-CT radiopharmaceutical automatic infusion device.
Background
PET-CT is a technology combining PET and CT together, provide the detailed function of focus and metabolism etc. molecular information by PET, and CT offers the accurate dissection location of the focus, the tomography image of every position of the whole body can be obtained in once visualization, have high degree of sensitiveness, position characteristics such as accurate, set up the venous access through intravenous injection physiological saline first, inject the radiopharmaceutical into the patient's vein fast and carry on the radiography in the course of examining, it is noninvasive to examine the process, can be intuitive and see the disease in the whole body affected part and situation, still there is very big development space in the future.
When a patient is subjected to PET-CT detection at present, physiological saline and radiopharmaceuticals need to be respectively extracted, for example, a radiopharmaceuticals automatic subpackaging injection instrument disclosed in the publication No. CN202671189U needs to be respectively extracted, since the physiological saline needs to be used for establishing a venous access before detection, the physiological saline needs to be immediately used for cleaning an injection propeller subsequently, the injection propeller needs to be pushed to and fro in the process and cannot be used for injecting the radiopharmaceuticals in time, the amount of the physiological saline needed during cleaning is about 3-4 times of that of the access, the injection propeller needs to be firstly vacuumized and can be pumped with the physiological saline, and the requirement on the stroke of the injection propeller is higher; for example, in the PET-CT radiopharmaceutical automatic infusion apparatus disclosed in CN104958831A, the opening and closing of a plurality of valves need to be controlled, which has a high requirement on the operation experience of the working personnel, and because the ratio of the radiopharmaceutical to the physiological saline is too large, if the operation is not very easy, the phenomenon of disordered injection of the liquid medicine is very easy to occur, and the operation of the whole apparatus is controlled by using conventional electrical components, which can be realized by matching with a certain control program, but the control method cannot achieve the loss or start delay of each component, for example, the rotation time of the peristaltic pump is set by the control program, which is basically determined according to the pumping efficiency of the peristaltic pump itself, but the peristaltic pump needs to idle for a period of time during the use in the infusion process, which results in that the heating condition is aggravated, which is not beneficial for continuous use, and the idle process can be counted in the set time to affect the actual pumping amount.
Disclosure of Invention
The invention aims to provide a PET-CT radioactive drug automatic infusion device which can reduce the use of various sensors, reduce the equipment failure caused by the damage of electrical elements, does not need to be provided with a complicated control system, and has better stability compared with the conventional manual control or control by designing the control system.
The technical scheme adopted by the invention is as follows:
an automatic infusion device for PET-CT radiopharmaceuticals, comprising:
the radiation protection box body is internally provided with a control module;
the baffle is integrally formed inside the radiation-proof box body, the inner cavity of the radiation-proof box body is divided into a storage cavity and a liquid mixing cavity, a normal saline storage tank and a radiopharmaceutical storage tank are placed inside the storage cavity, and a liquid mixing barrel is fixedly installed inside the liquid mixing cavity;
the siphon module is arranged between the storage cavity and the liquid mixing cavity, comprises two siphons and is used for communicating the normal saline storage tank, the radiopharmaceutical storage tank and the liquid mixing barrel;
the pressure pumping module is arranged inside the liquid mixing barrel and is used for pumping gas inside the siphon tube and reducing air pressure inside the siphon tube, and when the siphon tube is inserted into the physiological saline storage tank and the radioactive drug storage tank, liquid medicine inside the siphon tube flows into the liquid mixing barrel through the siphon tube;
the infusion module, the infusion module install in the inside of the box of protecting against radiation, with the inside of mixing the liquid bucket is linked together, including peristaltic pump and connecting pipe, peristaltic pump fixed mounting in the inside of the box of protecting against radiation, the output fixedly connected with transfer line of peristaltic pump, the connecting pipe will the peristaltic pump with mix the liquid bucket and link together, the action of pump module can with mix the inside liquid medicine of liquid bucket and extrude extremely the inside of peristaltic pump.
Preferably, wherein: the control module comprises a control panel and an integrated circuit board, the control panel is assembled on the upper surface of the radiation-proof box body, the integrated circuit board is assembled inside the radiation-proof box body, a communication module is integrated on the integrated circuit board, and the communication module is at least externally connected with an interaction device through a wire.
Preferably, wherein: the siphon includes fixed pipe, liquid feeding pipe and registration arm, fixed pipe with it is linked together to mix the liquid bucket, the liquid feeding pipe run through the upper surface of radiation protection box and with normal saline storage jar and radiopharmaceutical storage jar rotate to be connected, one side of liquid feeding pipe with fixed pipe fixed connection, the registration arm slip cap is located the inside of normal saline storage jar and radiopharmaceutical storage jar.
Preferably, wherein: the equal fixed mounting in top of normal saline storage jar and radiopharmaceutical storage jar has driving motor, driving motor's output fixed mounting has drive gear, drive gear's below meshing has the linkage gear, the fixed cover of linkage gear connect in the surface of liquid feeding pipe.
Preferably, wherein: the upper port of the liquid feeding pipe is provided with a sealing plug, and the top of the liquid feeding pipe is fixedly sleeved with an adjusting knob.
Preferably, wherein: the top of the positioning tube is fixedly sleeved with an external thread ring, the inner edge of the liquid feeding tube is provided with an internal thread matched with the external thread ring, and the top of the positioning tube is also provided with a liquid guide hole communicated with the inside of the liquid feeding tube.
Preferably, wherein: work as the external screw thread ring is located the liquid feeding pipe with during the top of fixed pipe intercommunication department, the inside liquid medicine of normal saline storage jar and radiopharmaceutical holding vessel via the liquid feeding pipe with space between the registration arm flows extremely the inside of fixed pipe, works as the external screw thread ring is located the liquid feeding pipe with during the below of fixed pipe intercommunication department, normal saline storage jar with the inside liquid medicine of radiopharmaceutical holding vessel flows extremely through the last port by the registration arm the inside of fixed pipe.
Preferably, wherein: the pumping module comprises an electric telescopic rod, a connecting rod and a piston block, the electric telescopic rod is fixedly installed in the radiation-proof box body, the connecting rod is fixedly connected to the output end of the electric telescopic rod, the piston block is fixedly connected to one end of the connecting rod, and the piston block is slidably sleeved in the liquid mixing barrel.
Preferably, wherein: the inside integrated into one piece of liquid mixing barrel has the fixed plate, the fixed plate cover is located the inside of connecting rod and piston piece, one side of fixed plate bottom has been seted up and has been passed through the groove, the inside that passes through the groove be provided with liquid mixing barrel inner wall fixed connection's radiation volume detector.
Preferably, wherein: the fixed plate will the internal partitioning of mixing the liquid bucket is normal saline chamber and radiopharmaceutical chamber, the inside integrated into one piece in intercommunication department in connecting pipe and radiopharmaceutical chamber has the sealing ring, one side of sealing ring is provided with the closing plate, the axle center department of closing plate one side is provided with the stripper bar that runs through the sealing ring, the stripper bar with be located the piston piece fixed connection in radiopharmaceutical intracavity portion, the axle center department fixedly connected with elastic component of closing plate opposite side, the elastic component is kept away from the one end fixedly connected with base of closing plate, the inside of connecting pipe is located to the base fixed the inlaying.
The invention has the technical effects that:
the siphon module is designed, the siphon effect is utilized, on the premise of extracting quantitative normal saline or radioactive drugs, manual control of opening and closing of the electromagnetic valve is not needed, step-by-step operation is not needed for extraction of the normal saline and the radioactive drugs, the operation can be completed at one time, opening and closing of the pipeline are not needed to be controlled through the electromagnetic valve and the like, the phenomenon of disordered injection of liquid medicine due to poor operation is avoided, the use of various sensors is reduced, the faults of equipment caused by damage of electrical elements are reduced, a complex control system is not needed, and compared with the conventional manual control or control system design control, the stability is better;
the infusion module is designed, and partial normal saline or radiopharmaceutical can be injected into the infusion module before the infusion module operates, so that liquid exists before the peristaltic pump operates, the peristaltic pump is prevented from idling, the injection time of the liquid medicine is correspondingly reduced, and the requirement that the radiopharmaceutical needs to be injected immediately after the venous access is established is met;
the invention adopts the design of the pumping module, and the pumping module can pump the gas in the siphon tube, so that the air pressure in the siphon tube is reduced, and further the liquid medicine in the normal saline storage tank and the radiopharmaceutical storage tank can flow into the liquid mixing barrel through the inside of the siphon tube, and once the siphon is achieved, the liquid medicine can automatically and quantitatively flow into the liquid mixing barrel under the inertia of the self-flow without human intervention;
the invention adopts the design of the siphon, the adjustable siphon can determine the depth of the siphon entering the physiological saline storage tank and the radiopharmaceutical storage tank, thereby ensuring the amount of the siphon liquid medicine, and under the condition that the interaction equipment can not be supported by electric power, the radiation quantity received by the staff can be reduced by manual adjustment in cooperation with the action of the radiation-proof box body, so that the operation mode of the device is more flexible.
Drawings
FIG. 1 is a schematic view of an overall apparatus in an embodiment of the present invention;
FIG. 2 is a sectional front view of the interior of a radiation shielding case in an embodiment of the present invention;
FIG. 3 is a schematic rear sectional view of the interior of a radiation shielding case in an embodiment of the present invention;
FIG. 4 is an enlarged schematic view of the invention at A in FIG. 3;
FIG. 5 is a schematic cross-sectional view of the interior of a mixing barrel in an embodiment of the present invention;
FIG. 6 is a schematic view of a siphon tube in an embodiment of the present invention;
FIG. 7 is an exploded view of the interior of a liquid mixing tank in accordance with an embodiment of the present invention;
fig. 8 is an enlarged view of the invention at B in fig. 7.
In the drawings, the components represented by the respective reference numerals are listed below:
1. a radiation-proof box body; 101. a storage chamber; 102. a liquid mixing cavity; 2. a partition plate; 3. a normal saline storage tank; 4. a radiopharmaceutical storage tank; 5. a liquid mixing barrel; 501. a fixing plate; 5011. a through groove; 6. a siphon module; 601. a siphon tube; 6011. fixing the tube; 6012. a liquid feeding pipe; 6013. a positioning tube; 7. a pressure pumping module; 701. an electric telescopic rod; 702. a connecting rod; 703. a piston block; 7031. an extrusion stem; 8. a traction block; 9. an infusion module; 901. a peristaltic pump; 9011. a transfusion tube; 902. a connecting pipe; 9021. a seal ring; 9022. a sealing plate; 9023. an elastic member; 9024. a base; 10. a drive motor; 11. a transmission gear; 12. a linkage gear; 13. an externally threaded ring.
Detailed Description
In order that the objects and advantages of the invention will be more clearly understood, the following description is given in conjunction with the accompanying examples. It is to be understood that the following text is merely illustrative of one or more specific embodiments of the invention and does not strictly limit the scope of the invention as specifically claimed.
As shown in fig. 1-3, the present invention provides an automatic infusion device for PET-CT radiopharmaceuticals, comprising a radiation-proof box body 1, wherein a control module is assembled in the radiation-proof box body 1, and a power supply, preferably a rechargeable battery pack, electrically connected with the control module is also assembled, although optionally electrically connected with the mains supply, the control module comprises a control panel and an integrated circuit board, the control panel is assembled on the upper surface of the radiation-proof box body 1, the integrated circuit board is assembled inside the radiation-proof box body 1, the integrated circuit board is integrated with a communication module, the communication module is at least externally connected with an interactive device through a lead, a worker can remotely control the device through the interactive device so as to prevent the worker from being irradiated by the PET-CT radiopharmaceutical, the control module is assembled on the radiation-proof box body 1, the radiation-proof box body 1 is internally and integrally formed with a partition plate 2, the inner cavity of the radiation-proof box body 1 is divided into a storage cavity 101 and a liquid mixing cavity 102, a normal saline storage tank 3 and a radioactive drug storage tank 4 are placed in the storage cavity 101, normal saline and PET-CT radioactive drugs are respectively stored in the normal saline storage tank 3 and the radioactive drug storage tank 4, a liquid mixing barrel 5 is fixedly installed in the liquid mixing cavity 102, the upper surface of the liquid mixing barrel 5 is lower than the lower surfaces of the normal saline storage tank 3 and the radioactive drug storage tank 4, a siphon module 6 is arranged between the storage cavity 101 and the liquid mixing cavity 102 and used for sucking the normal saline and the PET-CT radioactive drugs, the siphon module 6 comprises siphon tubes 601, two siphon tubes 601 are arranged and used for communicating the normal saline storage tank 3, the radioactive drug storage tank 4 and the liquid mixing barrel 5, and a pumping module 7 is arranged in the liquid mixing barrel 5, the radiation-proof box body 1 is internally provided with an infusion module 9 for pumping the liquid medicine inside the liquid mixing barrel 5, the infusion module 9 is communicated with the inside of the liquid mixing barrel 5 and comprises a peristaltic pump 901 and a connecting pipe 902, the peristaltic pump 901 is fixedly arranged inside the radiation-proof box body 1, the peristaltic pump 901 is electrically connected with a power supply through a control panel, the output end of the peristaltic pump 901 is fixedly connected with an infusion pipe 9011, the infusion pipe 9011 is used for communicating with a syringe for injecting the liquid medicine, the peristaltic pump 901 is connected with the liquid mixing barrel 902 through the connecting pipe 902, and the inner diameters of the connecting pipe 901 and the infusion pipe 902 are smaller than 1 mm.
When the PET-CT radioactive drug injection device is used, when a patient needs to be injected with a PET-CT radioactive drug, a worker firstly operates the siphon module 6 and inserts the siphon tube 601 into the normal saline storage tank 3 and the radioactive drug storage tank 4, then an operator operates the pressure pumping module 7 to pump gas in the siphon tube 601, the air pressure in the siphon tube 601 is reduced, liquid drugs in the normal saline storage tank 3 and the radioactive drug storage tank 4 ascend along the interior of the siphon tube 601 and descend gradually, and the gas in the siphon tube 601 is emptied, at the moment, the liquid drugs in the normal saline storage tank 3 and the radioactive drug storage tank 4 automatically flow into the liquid mixing barrel 5 under the siphon action, until a liquid inlet of the siphon tube 601 is not contacted with the liquid drugs in the normal saline storage tank 3 and the radioactive drug storage tank 4 any more, at the moment, the siphon state stops, and under the inertia of the flowing liquid drugs, the liquid drugs in the siphon tube 601 do not return, manual control is not needed, and the use of various sensors and electromagnetic valves can be reduced, so that the phenomenon that equipment cannot normally operate due to faults of various electrical components can be reduced;
after the liquid medicine enters the liquid mixing barrel 5, the worker operates the pumping module 7 to move in the opposite direction, at this time, the liquid medicine inside the liquid mixing barrel 5 will gradually enter the inside of the connecting pipe 902, then flow into the inside of the peristaltic pump 901 through the connecting pipe 902, when a follow-up worker operates the peristaltic pump 901 to pump liquid medicine, the peristaltic pump 901 does not idle, so that the loss of the peristaltic pump 901 can be effectively reduced, and finally the peristaltic pump 901 can pump the liquid medicine into a syringe through the infusion tube 9011.
As shown in fig. 2, 3 and 4, the siphon 601 includes a fixed pipe 6011, a liquid feeding pipe 6012 and a positioning pipe 6013, the fixed pipe 6011 is communicated with the liquid mixing barrel 5, the fixed pipe 6011 is an inclined pipe, a lower end of the fixed pipe 6011 is fixedly connected with the liquid mixing barrel 5, a higher end of the fixed pipe 6012 is connected with the liquid feeding pipe 6012 through a rotary joint, the rotary joint is rotatably connected to an outer surface of the liquid feeding pipe 6012, the liquid feeding pipe 6012 penetrates through an upper surface of the radiation-proof box 1 and is rotatably connected with the saline storage tank 3 and the radiopharmaceutical storage tank 4, the liquid feeding pipe 6012 can respectively feed liquid into the saline storage tank 3 and the radiopharmaceutical storage tank 4, one side of the liquid feeding pipe 6012 is fixedly connected with the fixed pipe 6011 (the higher end), the positioning pipe 6013 is slidably sleeved inside the saline storage tank 3 and the radiopharmaceutical storage tank 4, and the amount of the liquid pumped by the siphon 601 can be determined by adjusting the position of the positioning pipe 6013.
On the basis, as shown in fig. 6, an external thread ring 13 is fixedly sleeved on the top of the positioning tube 6013, an internal thread matched with the external thread ring 13 is arranged on the inner edge of the liquid adding tube 6012, and then when the liquid adding tube 6012 rotates, the external thread ring 13 drives the positioning tube 6013 to move downwards under the action of thread transmission, the positioning tube 6013 moves towards the inside of the saline solution storage tank 3 and the radiopharmaceutical storage tank 4 and gradually sinks into the liquid medicine inside the positioning tube 6013, a liquid guide hole communicated with the inside of the liquid adding tube 6012 is further formed in the top of the positioning tube 6013, the outer diameter of the positioning tube 6013 is two thirds of the inner diameter of the liquid adding tube 6012, so that a certain gap exists between the positioning tube 6013 and the liquid adding tube 6012, the gap plays a role of excessive liquid medicine, can increase the moving stroke of the positioning tube 6013 in a certain space, and cannot affect the liquid feeding of the positioning tube 6011.
Specifically, when the external thread ring 13 is located above the connection between the liquid adding pipe 6012 and the fixed pipe 6011, the liquid medicine inside the saline storage tank 3 and the radiopharmaceutical storage tank 4 flows out to the inside of the fixed pipe 6011 through the gap between the liquid adding pipe 6012 and the positioning pipe 6013, and when the external thread ring 13 is located below the connection between the liquid adding pipe 6012 and the fixed pipe 6011, the liquid medicine inside the saline storage tank 3 and the radiopharmaceutical storage tank 4 flows out to the inside of the fixed pipe 6011 through the upper port of the positioning pipe 6013.
As shown in fig. 4, a driving motor 10 is fixedly installed above the saline storage tank 3 and the radiopharmaceutical storage tank 4, a transmission gear 11 is fixedly installed at an output end of the driving motor 10, a linkage gear 12 is engaged below the transmission gear 11, the linkage gear 12 and the transmission gear 11 are bevel gears with the same specification, and the linkage gear 12 is fixedly sleeved on an outer surface of the liquid filling pipe 6012, which is an application of conventional mechanical transmission and is used for driving the liquid filling pipe 6012 to rotate, and no excessive explanation is provided herein.
It should be noted that the internal thread and the external thread ring 13 of the liquid feeding tube 6012 are both configured as a single thread, and the bottom end of the positioning tube 6013 is initially attached to the liquid level of the liquid medicine inside the saline storage tank 3 and the radiopharmaceutical storage tank 4;
setting the thread pitch of the internal thread of the liquid adding pipe 6012 and the external thread ring 13 as P, setting the single displacement distance of the positioning pipe 6013 as L, and setting the relation between the two as L = (theta/2 pi) × S1, wherein theta is the rotation angle of the liquid adding pipe 6012, pi is the circumferential rate, S1 is the lead, in the single thread, the lead is equal to the thread pitch, namely S1= P, the inner cavities of the physiological saline storage tank 3 and the radiopharmaceutical storage tank 4 are both set as regular cylindrical chambers, the bottom area of the inner cavity is S2, and then after the positioning pipe 6013 displaces, the subsequent volume of the liquid medicine capable of siphoning is V = S2 × L;
the thread pitch P of the internal thread of the liquid adding pipe 6012 and the bottom areas S2 of the inner cavities of the normal saline storage tank 3 and the radiopharmaceutical storage tank 4 are fixed values, during actual operation, a worker can determine the required normal saline amount and the PET-CT radiopharmaceutical amount in advance according to the physical condition of a patient, namely the value of the volume V of the liquid medicine to be siphoned is determined, and the single displacement distance of the corresponding positioning pipe 6013 can be correspondingly determined;
finally, obtaining the rotation number theta = (V x 2 pi)/S1 x S2 (DEG) of the liquid adding pipe 6012;
because the sensitivity of the CT scanner is different, the amount of the PET-CT radiopharmaceutical to be injected is also different, and the specification of the components is not particularly limited, and the PET-CT radiopharmaceutical can be specifically set according to the actual matched CT scanner.
As shown in fig. 3 and 4, the upper port of the liquid adding tube 6012 is equipped with a plug, the plug is in threaded connection with the liquid adding tube 6012, when the liquid medicine in the saline solution storage tank 3 and the radiopharmaceutical storage tank 4 rises along the inside of the liquid adding tube 6012 under the siphon action, the liquid medicine can pass through the upper port of the positioning tube 6013 under the inertia action, but the plug can effectively block the liquid medicine, so that the liquid medicine cannot flow out from the inside of the liquid adding tube 6012, and an adjusting knob is fixedly sleeved at the top of the liquid adding tube 6012, under the condition that the mains supply or the power supply cannot supply power, a worker can drive the liquid adding tube 6012 to rotate by rotating the adjusting knob, the adjusting knob is provided with an indicating arrow, and under the condition of artificial adjustment, the indicating arrow can assist the worker to judge the number of rotation turns of the adjusting knob, so as to realize the operation of adjusting the position of the positioning tube 6013.
As shown in fig. 5, the pumping and pressing module 7 includes an electric telescopic rod 701, a connecting rod 702 and a piston block 703, the electric telescopic rod 701 is fixedly installed inside the radiation-proof box body 1, and is electrically connected with a power supply through a control panel, the end portion of the electric telescopic rod 701 is fixedly connected with a traction block 8, the connecting rod 702 is fixedly connected with the output end of the electric telescopic rod 701 through the traction block 8, the piston block 703 is fixedly connected with one end of the connecting rod 702, and the piston block 703 is slidably sleeved inside the liquid mixing barrel 5.
Specifically, when a liquid medicine needs to be pumped, a worker firstly adjusts the position of the positioning tube 6013, then controls the electric telescopic rod 701 through the control panel to enable the piston block 703 to move along the inside of the liquid mixing barrel 5, and further can extract gas inside the fixed tube 6011, so that the air pressure inside the fixed tube 6011 is reduced, the liquid medicines inside the saline storage tank 3 and the radiopharmaceutical storage tank 4 rise along the inside of the positioning tube 6013, and enter the inside of the fixed tube 6011 under the flowing potential energy thereof, and then form siphon and continuously flow to the inside of the liquid mixing barrel 5, when the liquid medicine needs to be injected to a patient, the worker controls the electric telescopic rod 701 to reversely run through the control panel, and then starts the peristaltic pump 901.
As shown in fig. 5, a fixing plate 501 is integrally formed inside the liquid mixing barrel 5 to divide the inside of the liquid mixing barrel 5 into a physiological saline chamber and a radiopharmaceutical chamber, the fixing plate 501 is sleeved inside the connecting rod 702 and the piston block 703, a through groove 5011 is formed in one side of the bottom of the fixing plate 501, and a dosimetry detector fixedly connected to the inner wall of the liquid mixing barrel 5 is disposed inside the through groove 5011.
Further, the piston block 703 is divided into two by the fixing plate 501, the connecting rod 702 is divided into a connecting section a and a connecting section b by the fixing plate 501, the connecting section a is fixedly connected with the piston block 703 located in the saline chamber, and the connecting section b is slidably connected with the piston block 703 located in the radiopharmaceutical chamber.
In addition, on the basis, two arc-shaped baffles are fixedly connected to the connecting section b, the two arc-shaped baffles are located on two sides of the piston block 703, in an initial state, the arc-shaped baffle close to the connecting pipe 902 is far away from the piston block 703, at this time, when the electric telescopic rod 701 pulls the connecting rod 702 to move, the connecting rod 702 can drive the piston block 703 and the arc-shaped baffles located inside the saline cavity to move, the piston block 703 located inside the radiopharmaceutical cavity cannot move, when the arc-shaped baffle close to the connecting pipe 902 is attached to the piston block 703, the piston block can move, correspondingly, when the connecting rod 702 moves reversely, saline inside the saline cavity can enter the peristaltic pump 901 through the connecting pipe 902 in advance, at this time, the peristaltic pump 901 can inject saline into the vein of the patient in advance, so as to establish a venous access, after the saline injection is completed, the electric telescopic rod 701 continues to operate, and at this time, the electric telescopic rod extrudes 701 the PET-CT radiopharmaceutical to enter the vein of the patient through the connecting pipe 902, the peristaltic pump 901, the infusion tube 9011 and the syringe.
As shown in fig. 7 and 8, a sealing ring 9021 is integrally formed inside a communication portion between the connection pipe 902 and the radiopharmaceutical cavity, a sealing plate 9022 is disposed on one side of the sealing ring 9021, an extrusion rod 7031 penetrating the sealing ring 9021 is disposed on an axial center of one side of the sealing plate 9022, the extrusion rod 7031 is fixedly connected to the piston block 703 located inside the radiopharmaceutical cavity, an elastic member 9023 is fixedly connected to an axial center of the other side of the sealing plate 9022, a base 9024 is fixedly connected to one end of the elastic member 9023, which is far away from the sealing plate 9022, and the base 9024 is fixedly embedded inside the connection pipe 902.
Based on the structure, when the piston block 703 in the saline cavity extrudes the saline, the extrusion rod 7031 is far away from the sealing plate 9022, so that the peristaltic pump 901 can only extract the saline during operation, the PET-CT radiopharmaceutical does not enter the vein during the process of establishing the vein access, and subsequently, after the vein access is established, the electric telescopic rod 701 is continuously operated to drive the piston block 703 in the radiopharmaceutical cavity to displace, at the moment, the piston block 703 drives the extrusion rod 7031 to extrude the sealing plate 9022, the sealing plate 9022 releases the sealing of the sealing ring 9021, and the PET-CT radiopharmaceutical can be extracted by the peristaltic pump 901 and finally enters the vein of the human body through the infusion tube 9011 and the injector.
The working principle of the invention is as follows: when a patient needs to be injected with a PET-CT radiopharmaceutical, a worker firstly operates the siphon module 6 and inserts the siphon tube 601 into the physiological saline storage tank 3 and the radiopharmaceutical storage tank 4, then an operator operates the pumping module 7 to pump gas in the siphon tube 601, the gas pressure in the siphon tube 601 is reduced, liquid medicines in the physiological saline storage tank 3 and the radiopharmaceutical storage tank 4 rise and fall along the inside of the siphon tube 601, and the gas in the siphon tube 601 is gradually emptied, at this time, the liquid medicines in the physiological saline storage tank 3 and the radiopharmaceutical storage tank 4 flow into the mixing barrel 5 under the siphon action, until a liquid inlet of the siphon tube 601 no longer contacts the liquid medicines in the physiological saline storage tank 3 and the radiopharmaceutical storage tank 4, at this time, the siphon state stops, and the liquid medicines in the siphon tube 601 do not flow back under the inertia of the flowing of the liquid medicines, artificial control is not needed, and the use of various sensors and electromagnetic valves can be reduced, so that the phenomenon that equipment cannot normally operate due to faults of various electrical components is reduced;
after the liquid medicine enters into mixing barrel 5, the staff operation is taken out and is pressed module 7 reverse motion, the liquid medicine of the inside of mixing barrel 5 this moment will enter into the inside of connecting pipe 902 gradually, then flow into the inside of peristaltic pump 901 via connecting pipe 902, follow-up staff when operation peristaltic pump 901 draws the liquid medicine, the phenomenon of idle running can not appear in peristaltic pump 901, and then can effectual reduction peristaltic pump 901's loss, peristaltic pump 901 alright finally with the liquid medicine via transfer line 9011 pump into the syringe.
The foregoing is only a preferred embodiment of the present invention, and it should be noted that, for those skilled in the art, various modifications and amendments can be made without departing from the principle of the present invention, and these modifications and amendments should also be considered as the protection scope of the present invention. Structures, devices, and methods of operation not specifically described or illustrated herein are generally practiced in the art without specific recitation or limitation.
Claims (10)
1. An automatic infusion device of PET-CT radioactive medicines is characterized in that: the method comprises the following steps:
the radiation-proof box body (1), wherein a control module is assembled in the radiation-proof box body (1);
the inner cavity of the radiation-proof box body (1) is divided into a storage cavity (101) and a liquid mixing cavity (102) by a partition plate (2), a normal saline storage tank (3) and a radiopharmaceutical storage tank (4) are respectively arranged in the storage cavity (101), and a liquid mixing barrel (5) is fixedly arranged in the liquid mixing cavity (102);
the siphon module (6) is arranged between the storage cavity (101) and the liquid mixing cavity (102), the siphon module (6) comprises siphon pipes (601), and the siphon pipes (601) are arranged in two and used for sequentially connecting the normal saline storage tank (3), the radiopharmaceutical storage tank (4) and the liquid mixing barrel (5) to form a communicating structure;
the pressure pumping module (7) is arranged inside the liquid mixing barrel (5), and is used for pumping gas inside the siphon tube (601) and reducing the air pressure inside the siphon tube (601), and after the siphon tube (601) is inserted into the physiological saline storage tank (3) and the radioactive drug storage tank (4), the liquid medicine inside the siphon tube (601) flows to the inside of the liquid mixing barrel (5) through the siphon tube (601);
the infusion module (9) is installed inside the radiation-proof box body (1) and communicated with the inside of the liquid mixing barrel (5), and comprises a peristaltic pump (901) and a connecting pipe (902), the peristaltic pump (901) is fixedly installed inside the radiation-proof box body (1), an infusion pipe (9011) is fixedly connected to the output end of the peristaltic pump (901), the peristaltic pump (901) and the liquid mixing barrel (5) are connected together through the connecting pipe (902), and the liquid medicine inside the liquid mixing barrel (5) can be squeezed into the peristaltic pump (901) through the action of the pumping and pressing module (7).
2. An automatic PET-CT radiopharmaceutical infusion device as set forth in claim 1, wherein: the control module comprises a control panel and an integrated circuit board, the control panel is assembled on the upper surface of the radiation-proof box body (1), the integrated circuit board is assembled inside the radiation-proof box body (1), a communication module is integrated on the integrated circuit board, and the communication module is at least externally connected with an interaction device through a wire.
3. An automatic PET-CT radiopharmaceutical infusion device as set forth in claim 1, wherein: siphon (601) are including fixed pipe (6011), liquid feeding pipe (6012) and registration arm (6013), fixed pipe (6011) with it is linked together to mix liquid bucket (5), liquid feeding pipe (6012) run through the upper surface of protecting against radiation box (1) and with normal saline storage jar (3) and radiopharmaceutical storage jar (4) rotate the connection, one side of liquid feeding pipe (6012) with fixed pipe (6011) fixed connection, registration arm (6013) slip cap is located the inside of normal saline storage jar (3) and radiopharmaceutical storage jar (4).
4. An automatic infusion device of PET-CT radiopharmaceuticals according to claim 3, characterized by: the equal fixed mounting in top of normal saline storage jar (3) and radiopharmaceutical storage jar (4) has driving motor (10), the output fixed mounting of driving motor (10) has drive gear (11), the below meshing of drive gear (11) has linkage gear (12), linkage gear (12) fixed cup joint in the surface of liquid feeding pipe (6012).
5. An automatic infusion device of PET-CT radiopharmaceuticals according to claim 3, characterized by: the upper end opening of the liquid adding pipe (6012) is provided with a sealing plug, and the top of the liquid adding pipe (6012) is fixedly sleeved with an adjusting knob.
6. An automatic PET-CT radiopharmaceutical infusion device as set forth in claim 3, wherein: an external thread ring (13) is fixedly sleeved on the top of the positioning pipe (6013), an internal thread matched with the external thread ring (13) is arranged on the inner edge of the liquid adding pipe (6012), and a liquid guide hole communicated with the inside of the liquid adding pipe (6012) is further formed in the top of the positioning pipe (6013).
7. An automatic infusion device of PET-CT radiopharmaceuticals according to claim 6, characterized by: when external screw thread ring (13) is located add liquid pipe (6012) with when fixed pipe (6011) top of intercommunication department, the inside liquid medicine of normal saline storage jar (3) and radiopharmaceutical storage jar (4) via add liquid pipe (6012) with space between registration arm (6013) flows to the inside of fixed pipe (6011), when external screw thread ring (13) is located add liquid pipe (6012) with when fixed pipe (6011) below of intercommunication department, normal saline storage jar (3) with the inside liquid medicine of radiopharmaceutical storage jar (4) via the upper end mouth of registration arm (6013) flows to the inside of fixed pipe (6011).
8. An automatic infusion device of PET-CT radiopharmaceuticals according to claim 1, characterized by: the pumping and pressing module (7) comprises an electric telescopic rod (701), a connecting rod (702) and a piston block (703), the electric telescopic rod (701) is fixedly installed in the radiation-proof box body (1), the connecting rod (702) is fixedly connected with the output end of the electric telescopic rod (701), the piston block (703) is fixedly connected with one end of the connecting rod (702), and the piston block (703) is slidably sleeved in the liquid mixing barrel (5).
9. An automatic infusion device of PET-CT radiopharmaceuticals according to claim 8, characterized by: mix the inside integrated into one piece of liquid bucket (5) and have fixed plate (501), fixed plate (501) cover is located the inside of connecting rod (702) and piston piece (703), one side of fixed plate (501) bottom has been seted up and has been run through groove (5011), the inside that runs through groove (5011) is provided with the dosimetry detector with mixing liquid bucket (5) inner wall fixed connection.
10. An automatic infusion device of PET-CT radiopharmaceuticals, according to claim 9, characterized by: the inner part of the liquid mixing barrel (5) is divided into a physiological saline cavity and a radioactive drug cavity by the fixing plate (501), a sealing ring (9021) is integrally formed inside a communication part of the connecting pipe (902) and the radioactive drug cavity, a sealing plate (9022) is arranged on one side of the sealing ring (9021), an extrusion rod (7031) penetrating through the sealing ring (9021) is arranged at the axis of one side of the sealing plate (9022), the extrusion rod (7031) is fixedly connected with a piston block (703) located inside the radioactive drug cavity, an elastic piece (9023) is fixedly connected to the axis of the other side of the sealing plate (9022), a base (9024) is fixedly connected to one end, far away from the sealing plate, of the elastic piece (9023), and the base (9024) is fixedly embedded inside the connecting pipe (902).
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| CN202211065887.3A CN115137912B (en) | 2022-09-01 | 2022-09-01 | Automatic PET-CT radioactive drug infusion device |
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| CN202211065887.3A CN115137912B (en) | 2022-09-01 | 2022-09-01 | Automatic PET-CT radioactive drug infusion device |
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