CN115109692A

CN115109692A - Convenient type nucleic acid detector

Info

Publication number: CN115109692A
Application number: CN202210849672.4A
Authority: CN
Inventors: 陈芳
Original assignee: Ningbo Huamei Hospital University of CAS
Current assignee: Ningbo Huamei Hospital University of CAS
Priority date: 2022-07-19
Filing date: 2022-07-19
Publication date: 2022-09-27

Abstract

The invention discloses a convenient nucleic acid detector which comprises an equipment shell and a nucleic acid detection assembly, wherein the nucleic acid detection assembly comprises a central processing unit and a connecting pipe communicated with the central processing unit, an air blowing pipe is arranged at the end part of the connecting pipe in an inserting mode, a storage pipe assembly is arranged in the inner cavity of the equipment shell and comprises a storage pipe box, a rotatable feeding roller is attached to the bottom end opening of the storage pipe box, a material receiving groove matched with the air blowing pipe is formed in the outer wall of the feeding roller, and a material guide track is obliquely arranged at the position below one side of the feeding roller. The invention can blow air to the central processing unit in the equipment shell through the air blowing pipe, so that the central processing unit extracts the throat swab specimen from the air and directly introduces the throat swab specimen into the assay system for detection, thereby being convenient for rapidly screening the negativity or the positivity of nucleic acid of a detector, saving the high-intensity operation and the high-cost operation of manual sampling and improving the work quality of resisting the new coronavirus epidemic.

Description

Convenient type nucleic acid detector

Technical Field

The invention relates to the field of nucleic acid detection, in particular to a convenient nucleic acid detector.

Background

At present, due to the high infectivity and the hiding property of the new coronavirus, large-area nucleic acid sampling operation is often required, and virus-carrying patients and infected patients are screened through nucleic acid sampling and detection, so that the wide spread of the virus is avoided.

However, most of the existing nucleic acid sampling is manual sampling, which has the disadvantages that the labor cost and the material cost required to be sent are high when large-area nucleic acid sampling is carried out, meanwhile, the manual sampling needs to be carried out in a centralized way, the intermediate time is long, the virus propagation and diffusion area is easily increased, and the work quality of epidemic prevention operation is reduced.

Disclosure of Invention

The present invention has been made to solve the above-mentioned problems occurring in the prior art, and an object of the present invention is to provide a convenient nucleic acid detector.

In order to achieve the purpose, the invention provides the following technical scheme: a portable nucleic acid detector comprising:

the equipment shell is used for integrated installation and protection of components;

the nucleic acid detection assembly is used for detecting the breath-type nucleic acid detection of a person;

the nucleic acid detection assembly comprises a central processing unit arranged in the inner cavity of the equipment shell and a connecting pipe arranged on the outer wall of the equipment shell and communicated with the central processing unit, and an air blowing pipe is arranged at the end part of the connecting pipe in an inserting manner;

the equipment shell inner chamber is provided with the pipe storage subassembly that is used for the gas blow pipe to store and the ejection of compact, the pipe storage subassembly is including depositing the pipe box, it is provided with rotatable feed roll to deposit the laminating of pipe box bottom port department, the outer wall of feed roll is seted up and is connect the silo that suits with the gas blow pipe, the below position department slope of feed roll one side is provided with the fixed guide track that sets up with equipment shell inner wall bottom discharge gate.

Preferably, the equipment shell comprises box and back of the body lid, the avris at the box back passes through the hinge with the positive avris of back of the body lid and articulates, the fixed mounting that is used for equipment shell installation fixed that is provided with of outer wall of back of the body lid, one side between back of the body lid and the box is provided with and is used for both to lock fixed lock.

Preferably, a sealing plate is hinged to a discharge port at the bottom of the front face of the box body, a material receiving plate with an L-shaped cross section is fixedly arranged at a position below the discharge port on the front face of the box body, and an inclined slope is arranged at the top end of the inner side of the material receiving plate.

Preferably, the two ends of the feed roller are rotatably provided with connecting plates, the outer walls of the two connecting plates are respectively fixedly arranged on the inner wall of the box body, and the bottom of the inner cavity of the equipment shell is provided with a driving motor for driving the feed roller to rotate.

Preferably, be provided with ejection of compact subassembly between feed roll and the sealing plate, ejection of compact subassembly is including fixed the first gear that sets up in the feed roll tip, the outer wall meshing of first gear is provided with the second gear, the avris of second gear terminal surface is articulated to be provided with the connecting rod, the one end of connecting rod is rotated and is provided with the actuating lever, the outer wall of actuating lever slides to alternate and is provided with the uide bushing fixed mutually with the connecting rod.

Preferably, the diameter of the first gear is twice the diameter of the second gear, the end of the driving rod is provided with a roller through the rotation of the arranged groove, the outer wall of the roller is attached to the top of the inner side of the sealing plate, and the second gear is arranged through the rotation of the connecting plate at the corresponding position of the rotating shaft.

Preferably, the central processing unit comprises a central processing unit, a detection unit, an assay unit, a prompt unit, an alarm unit and a disinfection unit, wherein the detection unit is used for collecting a pharyngeal swab sample for detecting gas exhaled by a person and transmitting the collected pharyngeal swab sample to the central processing unit, the central processing unit transmits the collected pharyngeal swab sample data to the assay unit for assay and transmits an assay result back to the central processing unit, and the central processing unit controls the alarm unit to give an alarm if the assay result is positive according to whether the assay result is positive or not;

after the detection of a single individual is finished, the central processing unit controls the disinfection unit to disinfect the detection unit, and after the detection unit finishes the sampling of the gas throat swab, the central processing unit controls the prompt unit to send out a voice prompt to inform the completion of the detection.

The invention has the technical effects and advantages that:

(1) the invention can blow air to the central processing unit in the equipment shell through the air blowing pipe, so that the central processing unit extracts the throat swab specimen from the air and directly introduces the throat swab specimen into the assay system for detection, thereby being convenient for rapidly screening the negativity or the positivity of nucleic acid of a detector, saving the high-intensity operation and the high-cost operation of manual sampling and improving the work quality of resisting the new coronavirus epidemic;

(2) according to the invention, through the pipe storage box, the feeding roller and the material guide rail of the material receiving groove box arranged in the equipment shell, the automatic discharging operation of the air blowing pipe can be realized, the storage and the single discharging of the air blowing pipe are convenient, so that a tester can sequentially extract the air blowing pipe for air blowing detection, and the pollution caused by directly placing the air blowing pipe outside and taking the air blowing pipe is avoided, thereby improving the protection performance of the nucleic acid detection operation;

(3) according to the invention, through the arrangement of the first gear, the second gear, the connecting rod, the driving rod and the guide sleeve which are arranged between the feeding roller and the sealing plate at the discharge port of the equipment shell, the feeding roller can rotate to discharge materials, and meanwhile, the first gear drives the second gear to rotate, so that the second gear drives the driving rod to move in parallel along the guide sleeve through the connecting rod, the sealing plate at the discharge port of the equipment shell is pushed open, the discharging of the gas blow pipe falls onto the material receiving plate conveniently, and meanwhile, a protection effect on the discharge port on the equipment shell can be achieved, thereby further enhancing the safety protection performance of the equipment.

Drawings

Fig. 1 is a schematic view of the overall structure of the present invention.

FIG. 2 is a schematic sectional view of the back side of the present invention.

Fig. 3 is a schematic perspective view of the feed roller of the present invention.

FIG. 4 is a schematic view of the top view of the present invention in partial cross section.

Fig. 5 is a schematic view of the enlarged structure at a point a in fig. 3 according to the present invention.

FIG. 6 is a side view partially in section.

FIG. 7 is a flow chart of the CPU of the present invention.

In the figure: 1. an equipment housing; 11. a back cover; 12. a box body; 13. a fixing member; 2. a nucleic acid detection component; 21. a connecting pipe; 22. an air blowing pipe; 23. a central processing unit; 3. a storage tube assembly; 31. a storage box; 32. a feed roller; 321. a material receiving groove; 33. a connecting plate; 34. a material guiding rail; 35. a drive motor; 4. a discharge assembly; 41. a sealing plate; 42. a material receiving plate; 43. a first gear; 44. a second gear; 45. a connecting rod; 46. a drive rod; 47. a guide sleeve; 48. and a roller.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

The present invention provides a convenient nucleic acid detector as shown in FIGS. 1 to 7, comprising:

the equipment shell 1 is used for integrated installation and protection of components, the equipment shell 1 consists of a box body 12 and a back cover 11, the side of the back of the box body 12 is hinged with the side of the front of the back cover 11 through a hinge, a sealing gasket is arranged at the joint between the box body 12 and the back cover 11 to increase the sealing property of the joint between the box body 12 and the back cover 11, a fixing piece 13 for installing and fixing the equipment shell 1 is fixedly arranged on the outer wall of the back cover 11, the whole equipment shell 1 is conveniently and fixedly installed on a wall or an installation support, the use convenience is increased, a door lock for locking and fixing the back cover 11 and the box body 12 is arranged on one side between the back cover 11 and the box body 12, the door lock can be purchased in the market at present and can meet the use requirements, the locking between the back cover 11 and the box body 12 is mainly realized, the protection property is increased, and the opening is convenient for overhauling of an internal structure;

nucleic acid detecting element 2 for measurement personnel's expiration formula nucleic acid detects, nucleic acid detecting element 2 is including setting up in the central processing unit 23 of 1 inner chamber of equipment shell and setting up in the connecting pipe 21 that 1 outer wall of equipment shell and central processing unit 23 are linked together, the tip interlude of connecting pipe 21 is provided with gas blow pipe 22, gas blow pipe 22 is disposable, adopt the mode installation of interference pressure equipment between gas blow pipe 22 and the connecting pipe 21, increase leakproofness and the stability of gas blow pipe 22 installation, convenient direct extraction simultaneously.

The central processing unit 23 comprises a central processing unit, a detection unit, an assay unit, a prompt unit, an alarm unit and a disinfection unit, wherein the detection unit is used for detecting the pharyngeal swab sample collection of the exhaled air of a person and transmitting the collected pharyngeal swab sample to the central processing unit, the central processing unit transmits the collected pharyngeal swab sample data to the assay unit for assay and transmits the assay result back to the central processing unit, the central processing unit judges whether the assay result is positive or not according to the assay result, if the assay structure is positive, the central processing unit controls the alarm unit to send out an alarm, the exhaled air is subjected to pharyngeal swab collection through the detection unit and then transmits the collected information to the central processing unit, so that the central processing unit transmits signals to the assay unit to assay and detect the collected data and transmits the assay structure to the central processing unit, and the central processing unit can judge whether the exhaled air is an infected person or a carrier according to the assay result, the rapid detection operation of nucleic acid is realized;

after the detection of a single individual is finished, the central processing unit controls the disinfection unit to disinfect the detection unit, after the detection unit finishes the sampling of the gas throat swab, the central processing unit controls the prompt unit to send a voice prompt to inform that the detection is finished, the disinfection unit can disinfect the detection unit to avoid the cross infection of outgoing lines, the prompt unit can prompt the detection to be finished, and the detection personnel can be prevented from continuously blowing or transiently blowing to influence the detection;

the inner cavity of the equipment shell 1 is provided with a storage tube component 3 used for storing and discharging the blowing tubes 22, the storage tube component 3 comprises a storage tube box 31, the storage tube box 31 is internally provided with a containing cavity for storing the blowing tubes 22, single-row or double-row storage is convenient, a rotatable feed roller 32 is attached to the bottom end port of the storage tube box 31, the outer wall of the feed roller 32 is provided with a receiving groove 321 matched with the blowing tubes 22, the feed roller 32 is matched with the receiving groove 321 on the feed roller, the outer wall of the feed roller 32 is attached to the bottom end port of the storage tube box 31, so that the blowing tubes 22 in the storage tube box 31 fall into the receiving groove 321, and the guide rails 34 fixedly arranged with a discharge port at the bottom of the inner wall of the equipment shell 1 are obliquely arranged at the lower position on one side of the feed roller 32 along with the rotation of the feed roller 32 after the receiving groove 321 rotates to the bottom position, the blowing tubes 22 automatically slide down to facilitate single discharge, the blowing pipe 22 which can conveniently slide from the receiving groove 321 directly rolls out from a discharge hole of the equipment shell 1, so that discharging is convenient, connecting plates 33 are rotatably arranged at two ends of the feeding roller 32, the outer walls of the two connecting plates 33 are respectively fixedly arranged with the inner wall of the box body 12, a driving motor 35 for driving the feeding roller 32 to rotate is arranged at the bottom of the inner cavity of the equipment shell 1, a camera for detecting the identity of a person can be arranged on the front surface of the equipment shell 1 to be used as a control switch of the driving motor 35 and the central processor 23, and the control can also be directly carried out by adopting a manual control switch;

a sealing plate 41 is hinged at a discharge port at the bottom of the front surface of the box body 12, a material receiving plate 42 with an L-shaped cross section is fixedly arranged at a position, below the discharge port, on the front surface of the box body 12, an inclined slope surface is arranged at the top end of the inner side of the material receiving plate 42, the sealing plate 41 can seal the discharge port on the equipment shell 1, the safety protection performance of the discharge port is improved, and the material receiving plate 42 can keep the blanking of the gas blowing pipe 22 stably placed;

a discharging component 4 is arranged between the feed roller 32 and the sealing plate 41, the discharging component 4 comprises a first gear 43 fixedly arranged at the end part of the feed roller 32, a second gear 44 is arranged on the outer wall of the first gear 43 in a meshed manner, a connecting rod 45 is hinged to the side of the end face of the second gear 44, one end of the connecting rod 45 is rotatably provided with a driving rod 46, a guide sleeve 47 fixed with the connecting plate 33 is slidably inserted and arranged on the outer wall of the driving rod 46, the diameter of the first gear 43 is twice that of the second gear 44, a roller 48 is rotatably arranged at the end part of the driving rod 46 through an opened groove, the outer wall of the roller 48 is attached to the top of the inner side of the sealing plate 41, the second gear 44 is rotatably arranged with the connecting plate 33 at the corresponding position through a rotating shaft, and synchronous transmission between the first gear 43 and the feed roller 32 is utilized, so that the feeding roller 32 rotates and simultaneously drives the first gear 43 to rotate, and the ratio of the first gear 43 to the second gear 44 is 2: 1, the transmission action of the first gear 43, the second gear 44, the connecting rod 45 and the driving rod 46, and the limit guide action of the guide sleeve 47 on the driving rod 46, so that the sealing plate 41 is opened when the feeding roller 32 is fed, and meanwhile, after the feeding is finished, the sealing plate 41 is automatically closed, and the overall safety protection performance of the equipment is improved.

The working principle of the invention is as follows: when a person to be detected needs to perform nucleic acid detection, the driving motor 35 can drive the feeding roller 32 to rotate 180 degrees through the power switch of the driving motor 35 on the device shell 1, the blowing pipe 22 in the storage box 31 falls into the receiving groove 321 and rotates to the bottom position along the feeding roller 32, then the blowing pipe slides from the receiving groove 321 onto the material guiding rail 34 and rolls along the material guiding rail 34, meanwhile, the feeding roller 32 rotates and simultaneously drives the first gear 43 to rotate, the first gear 43 drives the second gear 44 to rotate, the second gear 44 drives the connecting rod 45 to reciprocate back and forth for a cycle, so that the connecting rod 45 drives the driving rod 46 to reciprocate back and forth, when the driving rod 46 moves forward, the roller 48 is used for ejecting the sealing plate 41, the discharge hole on the device shell 1 is opened, and the blowing pipe 22 on the material guiding rail 34 can roll onto the material receiving plate 42, the detection device is convenient for a person to be detected to take, then the sealing plate 41 is closed, the driving motor 35 stops working, the person to be detected can insert the air blowing pipe 22 into the port of the connecting pipe 21 and blow air into the central processing unit 23 in the equipment shell 1 from the port of the air blowing pipe 22, so that the central processing unit 23 performs throat swab sampling and detection on the air blown out by the person to be detected, and whether the nucleic acid detection is positive or not is judged.

Finally, it should be noted that: although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that modifications may be made to the embodiments or portions thereof without departing from the spirit and scope of the invention.

Claims

1. A portable nucleic acid detector comprising:

the equipment shell (1) is used for integrated installation and protection of components;

a nucleic acid detection assembly (2) for breath-based nucleic acid detection of a person;

the method is characterized in that: the nucleic acid detection assembly (2) comprises a central processing unit (23) arranged in the inner cavity of the equipment shell (1) and a connecting pipe (21) arranged on the outer wall of the equipment shell (1) and communicated with the central processing unit (23), and an air blowing pipe (22) is arranged at the end part of the connecting pipe (21) in an inserting manner;

the utility model discloses an equipment shell (1) inner chamber is provided with and is used for blowing pipe (22) to store and deposit pipe assembly (3) of the ejection of compact, deposit pipe assembly (3) including depositing pipe box (31), it is provided with rotatable feed roll (32) to deposit the laminating of pipe box (31) bottom port department, the outer wall of feed roll (32) is seted up and is met silo (321) that suits with blowing pipe (22), the lower position department slope of feed roll (32) one side is provided with guide track (34) with the fixed setting of equipment shell (1) inner wall bottom discharge gate.

2. The portable nucleic acid detector of claim 1, wherein the equipment housing (1) is composed of a box body (12) and a back cover (11), the side of the back surface of the box body (12) is hinged with the side of the front surface of the back cover (11) through a hinge, a fixing part (13) for fixing and installing the equipment housing (1) is fixedly arranged on the outer wall of the back cover (11), and a door lock for locking and fixing the back cover (11) and the box body (12) is arranged on one side of the back cover.

3. The portable nucleic acid detector according to claim 2, wherein a sealing plate (41) is hinged to the discharge opening at the bottom of the front surface of the case (12), a receiving plate (42) with an L-shaped cross section is fixedly arranged at the position of the front surface of the case (12) below the discharge opening, and an inclined slope is arranged at the top end of the inner side of the receiving plate (42).

4. The convenient nucleic acid detector according to claim 1, wherein the two ends of the feed roller (32) are rotatably provided with connecting plates (33), the outer walls of the two connecting plates (33) are respectively fixedly arranged with the inner wall of the box body (12), and the bottom of the inner cavity of the equipment shell (1) is provided with a driving motor (35) for driving the feed roller (32) to rotate.

5. The portable nucleic acid detector according to claim 1, wherein a discharging assembly (4) is disposed between the feeding roller (32) and the sealing plate (41), the discharging assembly (4) comprises a first gear (43) fixedly disposed at an end of the feeding roller (32), a second gear (44) is engaged with an outer wall of the first gear (43), a connecting rod (45) is hinged to an edge side of an end face of the second gear (44), a driving rod (46) is rotatably disposed at one end of the connecting rod (45), and a guide sleeve (47) fixed to the connecting plate (33) is slidably inserted into an outer wall of the driving rod (46).

6. The portable nucleic acid detector according to claim 5, wherein the diameter of the first gear (43) is twice the diameter of the second gear (44), the end of the driving rod (46) is rotatably provided with a roller (48) through a groove, the outer wall of the roller (48) is attached to the top of the inner side of the sealing plate (41), and the second gear (44) is rotatably provided with the connecting plate (33) at the corresponding position through a rotating shaft.

7. The portable nucleic acid detector according to claim 1, wherein the central processing unit (23) comprises a central processing unit, a detection unit, an assay unit, a prompt unit, an alarm unit and a disinfection unit, the detection unit is used for detecting pharyngeal swab sample collection of exhaled air of a person and transmitting the collected pharyngeal swab sample to the central processing unit, the central processing unit transmits the collected pharyngeal swab sample data to the assay unit for assay and transmits an assay result back to the central processing unit, the central processing unit controls the alarm unit to give an alarm if the assay result is positive or not;