CN115104622B - Compound composition of glufosinate-ammonium and topramezone - Google Patents
Compound composition of glufosinate-ammonium and topramezone Download PDFInfo
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- CN115104622B CN115104622B CN202110301230.1A CN202110301230A CN115104622B CN 115104622 B CN115104622 B CN 115104622B CN 202110301230 A CN202110301230 A CN 202110301230A CN 115104622 B CN115104622 B CN 115104622B
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- ammonium
- topramezone
- glufosinate
- surfactant
- composition
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- IYMLUHWAJFXAQP-UHFFFAOYSA-N topramezone Chemical compound CC1=C(C(=O)C2=C(N(C)N=C2)O)C=CC(S(C)(=O)=O)=C1C1=NOCC1 IYMLUHWAJFXAQP-UHFFFAOYSA-N 0.000 title claims abstract description 79
- IAJOBQBIJHVGMQ-UHFFFAOYSA-N 2-amino-4-[hydroxy(methyl)phosphoryl]butanoic acid Chemical group CP(O)(=O)CCC(N)C(O)=O IAJOBQBIJHVGMQ-UHFFFAOYSA-N 0.000 title claims abstract description 73
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Classifications
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N57/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds
- A01N57/18—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-carbon bonds
- A01N57/20—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-carbon bonds containing acyclic or cycloaliphatic radicals
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/02—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
- A01N25/04—Dispersions, emulsions, suspoemulsions, suspension concentrates or gels
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/12—Powders or granules
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/12—Powders or granules
- A01N25/14—Powders or granules wettable
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
- A01N43/80—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,2
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01P—BIOCIDAL, PEST REPELLANT, PEST ATTRACTANT OR PLANT GROWTH REGULATORY ACTIVITY OF CHEMICAL COMPOUNDS OR PREPARATIONS
- A01P13/00—Herbicides; Algicides
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- Engineering & Computer Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Agronomy & Crop Science (AREA)
- Dentistry (AREA)
- Toxicology (AREA)
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Abstract
The invention relates to a compound composition of glufosinate-ammonium and topramezone, which comprises active ingredients, wherein the active ingredients comprise the glufosinate-ammonium and the topramezone with the mass ratio of 0.01-100:1. The components of the invention have good synergistic effect, can be effectively used for preventing and controlling perennial tolerant plants, older weeds and the like, effectively improves the preventing and controlling range of the glufosinate-ammonium and the topramezone, and remarkably prolongs the duration. Meanwhile, the preparation method of the composition is simple and easy to implement, processing equipment is easy to obtain, the cost is low, and the composition has obvious market popularization value and economic benefit.
Description
Technical Field
The invention belongs to the field of application of agricultural chemicals, and particularly relates to a compound composition of glufosinate-ammonium and topramezone.
Background
The chemical formula of the glufosinate-ammonium is C 5 H 12 NO 4 P has the formula weight of 181.27 and the chemical name of 4- [ hydroxy (methyl) phosphono ]]L-homoalanine is easy to dissolve in water, is not easy to dissolve in organic solvent, is stable to light, has a melting point of 214-216 ℃, and is a high-efficiency, low-toxicity and nonselective contact-killing phosphoric acid herbicide. The glufosinate-ammonium is L-glufosinate-ammonium, and the weeding activity of the glufosinate-ammonium is twice that of the racemic DL-glufosinate-ammonium mixture. Glufosinate inhibits glutamine synthetase, resulting in plantsThe nitrogen metabolism in the body is disturbed, ammonium ions accumulate and poison, so that chloroplast synthesis is influenced, photosynthesis is hindered, and the death of plants is finally caused. The glufosinate-ammonium has low toxicity, is safer, is easy to degrade in soil, is safe to crops, has wide weeding spectrum, high activity and quick weed killing, can prevent and kill more than 100 annual or perennial weeds, mainly contacts and kills weeds, and can not be transferred to other places, so that the glufosinate-ammonium is safe to aftercrop. The glufosinate-ammonium has very good water solubility, stable structure and convenient processing and mixing use.
Topramezone has a chemical formula of C 16 H 17 N 3 O 5 S, formula weight is 363.38, chemical name is 4- [3- (4, 5-dihydro-isoxazol-3-yl) -2-methyl-4-methylsulfonyl]-1-methyl-5-hydroxy-1H-pyrazole, a highly selective post-emergence herbicide for corn fields. The topramezone pyrazolone herbicide is a 4-hydroxyphenylpyruvate dioxygenase (HPPD) inhibitor, can be absorbed by root systems and overground parts of plants and is conducted upwards and downwards in the plants, is safe to corn, and stem and leaf spraying can be used for preventing and controlling annual grasses and broadleaf weeds such as crabgrass, green bristlegrass, goosefoot, amaranth, quinoa and the like in a broad spectrum.
The biological activities of different herbicides are different, the weed killing spectra are different, and the herbicide composition can play a good role in complementary synergism in theory, especially the herbicide composition with different action mechanisms and modes. However, in practical application, the effect of gain can not be achieved by compounding any herbicide, and the complementary effect is related to the compounding of different herbicides, the formulation of the composition and other ingredients, and the research and report on the compounding of the glufosinate-ammonium and the topramezone are less at present.
Disclosure of Invention
The invention aims to provide a compound composition of glufosinate-ammonium and topramezone, which is used for preventing and controlling the growth of undesirable vegetation and has a control effect gain.
In order to achieve the above purpose, the invention adopts the following technical scheme:
the invention provides a compound composition of glufosinate-ammonium and topramezone, which comprises active ingredients, wherein the active ingredients comprise the glufosinate-ammonium and the topramezone with the mass ratio of 0.01-100:1.
Preferably, the mass ratio of the glufosinate-ammonium to the topramezone is 1-50: 1.
further preferably, the mass ratio of the glufosinate-ammonium to the topramezone is 5-20: 1.
preferably, the mass of the active ingredient is 10% -85% of the total weight of the compound composition.
Preferably, the compound composition further comprises an auxiliary material, wherein the auxiliary material comprises 5% -20% of surfactant by weight of the total weight of the compound composition.
The surfactant is one or a combination of more than one selected from wetting agents, emulsifying agents and dispersing agents.
Further preferably, the surfactant is one or more selected from fatty alcohol polyoxyethylene ether, amine polyoxyethylene ether, alkyl glycoside, alkylbenzene sulfonate, alkyl sulfate, polycarboxylate, sodium lignin sulfonate and organosilicon.
Further preferably, the auxiliary materials further comprise one or more of an antifreezing agent, a solvent, a filler, a disintegrating agent, a defoaming agent, a binder and a pigment.
The antifreezing agent is one or a combination of more selected from glycerol, propylene glycol and ethylene glycol;
the solvent is one or a combination of more selected from water, ethanol, methanol, N-dimethylformamide, dimethyl sulfoxide, cyclohexanone, methyl oleate and soybean oil;
the filler is one or a combination of a plurality of diatomite, kaolin, bentonite, white carbon black and light calcium carbonate;
the disintegrating agent is one or a combination of more selected from ammonium sulfate, urea, polyvinylpyrrolidone, sodium sulfate, starch and derivatives thereof, cellulose, sodium bicarbonate, sodium lauryl sulfate, sodium alginate, bentonite and sodium chloride;
the adhesive is one or more selected from starch, gelatin, pregelatinized starch, acacia, polyvinylpyrrolidone, methylcellulose, hydroxypropyl methylcellulose, polyethylene glycol, polyvinyl alcohol, glucose and sucrose.
Preferably, the formulation of the compound composition of the glufosinate-ammonium and the topramezone is a soluble liquid, a suspending agent, an oil suspending agent, a soluble powder, a soluble granule, a wettable powder or water dispersible granules.
According to an embodiment, the compound composition of the glufosinate-ammonium and the topramezone comprises the following components in percentage by mass:
10% -60% of active ingredients;
5% -20% of a surfactant;
35-75% of solvent.
According to another embodiment, the compound composition of the glufosinate-ammonium and the topramezone comprises the following components in percentage by mass:
30% -85% of active ingredients;
5% -10% of a surfactant;
10 to 60 percent of filler.
Preferably, the formulation of the compound composition of the glufosinate-ammonium and the topramezone is a soluble liquid, a suspending agent, an oil suspending agent, soluble powder, soluble granules, wettable powder or water dispersible granules.
Preferably, when the compounded composition is a soluble liquid formulation, it comprises the following components in mass percent:
further preferably, when the compounded composition is a soluble liquid formulation, it comprises the following components in mass percent:
further preferably, when the compounded composition is a soluble liquid formulation, the solvent is water and the surfactant is an alkyl glycoside.
The preparation method of the compound combination with the soluble liquid formulation comprises the following steps:
adding the glufosinate-ammonium and the topramezone into a solvent, stirring and dissolving at the speed of 150-200 r/min at the temperature of 55-65 ℃, then adding other auxiliary materials, stirring uniformly, and cooling to room temperature to obtain the soluble liquid of the compound composition of the glufosinate-ammonium and the topramezone.
Preferably, when the compounded composition is a suspending agent, it comprises the following components in mass percent:
further preferably, when the compounded composition is a suspending agent, it comprises the following components in mass percent:
further preferably, when the compounded composition is a suspending agent, the solvent is water, and the surfactant is fatty alcohol-polyoxyethylene ether and/or polycarboxylate.
Preferably, when the compounded composition is an oil suspension, it comprises the following components in mass percent:
further preferably, when the compounded composition is an oil suspension, it comprises the following components in mass percent:
further preferably, when the compounded composition is an oil suspending agent, the solvent is methyl oleate, and the surfactant is fatty alcohol polyoxyethylene ether and/or alkylbenzene sulfonate.
The preparation method of the compound composition with the dosage form of suspending agent or oil suspending agent comprises the following steps:
adding the glufosinate-ammonium, the topramezone and the auxiliary materials into a solvent, uniformly stirring at the speed of 150-200 rpm, and grinding by a sand mill to prepare a suspending agent or an oil suspending agent of the compound composition of the glufosinate-ammonium and the topramezone.
Preferably, when the compounded composition is a soluble powder, it comprises the following components in mass percent:
further preferably, when the compounded composition is a soluble powder, it comprises the following components in mass percent:
further preferably, when the compounded composition is a soluble powder, the surfactant is alkylbenzene sulfonate and the filler is kaolin and/or diatomaceous earth.
Preferably, when the compounded composition is a soluble granule, it comprises the following components in mass percent:
further preferably, when the compounded composition is a soluble granule, it comprises the following components in mass percent:
further preferably, when the compounded composition is a soluble powder, the surfactant is an alkyl sulfate and/or polycarboxylate.
Preferably, when the compounded composition is a wettable powder, it comprises the following components in mass percent:
further preferably, when the compounded composition is a wettable powder, it comprises the following components in mass percent:
further preferably, when the compounded composition is a wettable powder, the surfactant is a polycarboxylate.
The preparation method of the compound composition with the dosage form of suspending agent or oil suspending agent comprises the following steps:
uniformly stirring the glufosinate-ammonium, the topramezone and the auxiliary materials, and carrying out superfine grinding by a jet mill to obtain soluble powder or wettable powder of the compound composition of the glufosinate-ammonium and the topramezone.
Preferably, when the compound composition is water dispersible granule, the compound composition comprises the following components in percentage by mass:
further preferably, when the compound composition is a water dispersible granule, the compound composition comprises the following components in percentage by mass:
further preferably, when the compounded composition is a water dispersible granule, the surfactant is polycarboxylate and/or lignosulfonate, and the filler is kaolin.
The preparation method of the compound composition with the dosage form of soluble granules or water dispersible granules comprises the following steps:
stirring and mixing the glufosinate-ammonium, the topramezone and the auxiliary materials uniformly, carrying out superfine grinding by a jet mill, adding water, kneading by a kneader, then extruding and granulating by an extrusion granulator, and drying to obtain soluble granules or water dispersible granules of the compound composition of the glufosinate-ammonium and the topramezone.
The compound composition of the glufosinate-ammonium and the topramezone can solve the problems that the existing herbicide is not thorough in control of field resistant weeds, resistant weeds and elderly weeds, has short duration and needs repeated application for many times. The invention takes the glufosinate-ammonium and the topramezone as active ingredients, and the active ingredients are mixed in a certain range, so that the synergistic weeding effect of the active ingredients is fully exerted under the cooperation of other components of the preparation, the drug effect is obviously better than that of the glufosinate-ammonium and the topramezone which are independently used, and meanwhile, the compound composition of the glufosinate-ammonium and the topramezone is simple and easy to implement, the product quality is stable, the market value is obvious, and the invention is suitable for large-scale popularization and application.
The compound composition of the glufosinate-ammonium and the topramezone is used for preventing and controlling the growth of undesirable vegetation, including weed control in non-cultivated fields, inter-forest weeding, orchard weeding, inter-row weeding of cultivated field crops, and field stubble cleaning before sowing or transplanting.
When in use, the dosage of the active ingredients of the compound composition of the glufosinate-ammonium and the topramezone is 115-1150 g/hectare.
Due to the application of the technical scheme, compared with the prior art, the invention has the following advantages:
the components of the invention have good synergistic effect, can be effectively used for preventing and controlling perennial tolerant plants, older weeds and the like, effectively improves the preventing and controlling range of the glufosinate-ammonium and the topramezone, and remarkably prolongs the duration. Meanwhile, the preparation method of the composition is simple and easy to implement, processing equipment is easy to obtain, the cost is low, and the composition has obvious market popularization value and economic benefit.
Detailed Description
All of the features disclosed in this specification, or all of the steps in a method or process disclosed, may be combined in any combination, except for the mutually exclusive features or steps.
The technical solution of the present invention will be further described with reference to specific embodiments, but the present invention should not be limited to these embodiments, and other equivalent or alternative features having similar purposes may be substituted unless specifically stated. Each feature is one example only of a generic series of equivalent or similar features, unless expressly stated otherwise. The contents described below are mass contents, and "%" is mass percent.
The glufosinate-ammonium is purchased from Zhejiang Yongnong chemical industry Co., ltd; topramezone was purchased from basf europe; the fatty alcohol polyoxyethylene ether is purchased from Jiangsu province sea-An petrochemical plant; alkyl glycosides were purchased from Shanghai Kaiki chemical Co., ltd; alkylbenzene sulfonates are available from Shanghai Shengzhou fine chemical Co., ltd; alkyl sulfates were purchased from ston full chemistry (Shanghai); polycarboxylates are available from Shandong Tai and Water treatment technologies Co., ltd; sodium lignin sulfonate was purchased from the company Jin Baonong of the state of the vortex yang county; the defoamer is purchased from the company of the Tai chemical industry, inc. of Nantong; polyethylene glycol was purchased from the sea-safe petrochemical plant in Jiangsu province; methylcellulose is available from Shanghai microphone Biochemical technologies Co., ltd; kaolin is purchased from Shanghai Valley research industries Co., ltd; diatomaceous earth was purchased from Shanghai research industries, inc.; bentonite was purchased from guangxi Runxing new materials limited; mesotrione was purchased from Anhui Zhongshan chemical Co., ltd; cyclosulfamide is purchased from bayer corporation; isoxaflutole was purchased from bayer corporation.
Example 1
Test report for testing weed activity by mixing glufosinate-ammonium and topramezone
Test purpose: the herbicidal effect of the glufosinate-ammonium and topramezone on the target weeds was determined under greenhouse potting conditions and evaluated for the combined effect.
Test target: green bristlegrass, crabgrass, purslane and abutilon.
Preparing a test material: the test soil was quantitatively loaded to 4/5 of the pot. The soil is completely wetted by adopting the infiltrating irrigation mode at the bottom of the pot. The pre-treated weed seeds to be tested which are sprouted until the weed seeds are exposed are uniformly sowed on the soil surface, a small amount of soil is covered according to the size of the seeds, the seeds are transplanted into a greenhouse for conventional culture after sowing, and water is supplemented in a pot bottom infiltrating irrigation mode. After emergence and before application, planting purslane, 5 plants per pot, 10 plants per pot.
The formulation design of the medicament compound: the two doses tested for weed control have complementary modes of action, so that the compound test adopts a Gowing method, and the compound proportion is shown in Table 1 (unit: g.a.i/ha).
TABLE 1
And (3) medicament treatment: according to the action characteristics of the medicament and the purpose of medicament mixing, a stem and leaf spraying method is adopted by test references of pesticide bioassay technology (published by Beijing agricultural university Press) and pesticide indoor bioassay test criteria herbicide NY/T1155.3-2006 and 1155.4-2006. The prepared potted weeds are placed in a spray tower, the pressure of the potted weeds is fixed by a rotary table, the quantity of the potted weeds is sprayed, the pressure is 0.4MPA, the sprayed liquid medicine is 10ml (the liquid medicine amount per mu is 33 Kg), and the potted weeds are settled for 1 minute. Each treatment was repeated 4 times, 3 pots per grass repeat. After the surface liquid medicine of the test material is naturally air-dried after the treatment, the test material is placed at 18-25 ℃ for conventional management, and water is replenished in a pot bottom infiltrating irrigation mode.
The investigation method comprises the following steps: cutting off overground parts of weeds after 14 days after the medicine, and weighing fresh weight; calculating fresh weight control effect. At the same time, signs of the victims were recorded. Such as: color change (yellowing, whitening, etc.); morphological changes (malformation, distortion of the heart lobes); growth changes (dehydration, wilting, dwarfing, tufting, etc.).
Data statistics and analysis: the two groups of agents have strong complementarity, and are treated by a Gowing method, and the fresh weight control effect (percentage,%) is calculated according to the formula (1).
E＝(C-T)*100/C…………………………(1)
Wherein: e, fresh weight prevention effect; c, controlling fresh weight of overground parts of weeds; t, the fresh weight of the overground parts of weeds is treated.
And calculating the theoretical prevention effect of the two medicaments according to the formula (2).
Wherein:
x-weed control when the dosage of herbicide A is P;
the weed control effect when the dosage of the herbicide B is Q is shown;
E 0 the theoretical prevention effect when the dosage of the herbicide A is P and the dosage of the herbicide B is Q;
e, when the dosage of the herbicide A is P, the actual prevention effect is realized when the dosage of the herbicide C is Q;
E-E 0 more than 10% is synergistic; E-E 0 -10% antagonism; E-E 0 Values between+10% is additive.
The results of the determination of the activity of the mixed clomazone and topramezone on weeds are shown in Table 2.
TABLE 2
As can be seen from Table 2, glufosinate-ammonium and topramezone were used alone to effectively inhibit weed growth only at high doses. After the combination, the efficacy of the indoor potted plant is obviously improved under different combination proportions,all treatments E-E 0 The values are all > -10%, and the combined evaluation shows obvious synergy or additive effect.
From the observation of weeds after the medicine, 3d after the medicine, each compound treatment weed shows the symptom of arginate-ammonium phosphine poisoning, then gradually spreads and necroses, and the phytotoxicity symptoms of various weeds are more obvious along with the increase of dosage. 5 days after the medicine, each compound treatment weed has topramezone poisoning symptoms such as white leaf, growth inhibition and the like, the compound treatment effect of different proportions is obviously better than that of each single dose, and the action speed is obviously faster than that of each single dose.
Example 2
A 10% glufosinate-ammonium +0.5% topramezone soluble liquid formulation was prepared, the raw material formulation of which is shown in table 3.
TABLE 3 Table 3
| Component (A) | Proportioning of |
| Paraquat-ammonium phosphine | 10% of the folding hundred |
| Topramezone | 0.5% of a hundred |
| Surfactant alkyl glycoside | 12％ |
| Defoaming agent | 0.1％ |
| Antifreezing agent glycol | 5％ |
| Water and its preparation method | Make up to 100% |
Adding the glufosinate-ammonium and the topramezone into water for dissolution, preserving heat at 60 ℃, stirring at 180 revolutions per minute until the raw materials are completely dissolved, adding the defoamer and the surfactant alkyl glycoside, stirring uniformly, and cooling to room temperature to obtain the 10.5% glufosinate-topramezone soluble liquid.
Example 3
40% of the arginate-ammonium phosphine+8% of topramezone suspending agent is prepared, and the raw material formula is shown in table 4.
TABLE 4 Table 4
| Component (A) | Proportioning of |
| Paraquat-ammonium phosphine | 40% of the folding hundred |
| Topramezone | 8% of the folding hundred |
| Surfactant fatty alcohol polyoxyethylene ether | 4％ |
| Surfactant polycarboxylate | 4％ |
| Antifreezing agent propylene glycol | 5％ |
| Water and its preparation method | Make up to 100% |
Adding the glufosinate-ammonium, the topramezone and the surfactant into water, stirring at 180 revolutions per minute until the raw materials are wetted and dissolved, and sanding by a sand mill to obtain the 48% glufosinate-topramezone suspension.
Example 4
24% of arginate-ammonium and 8% of topramezone oil suspending agent is prepared, and the raw material formula is shown in table 5.
TABLE 5
| Component (A) | Proportioning of |
| Paraquat-ammonium phosphine | 24% of the folding hundred |
| Topramezone | 8% of the folding hundred |
| Surfactant fatty alcohol polyoxyethylene ether | 12％ |
| Surfactant alkylbenzene sulfonate | 6％ |
| Bentonite clay | 2％ |
| Oleic acid methyl ester | Make up to 100% |
Adding the glufosinate-ammonium, the topramezone, the bentonite and the surfactant into methyl oleate, stirring at 180 revolutions per minute until the raw materials are wetted, and sanding by a sand mill to obtain the 32% glufosinate-topramezone oil suspending agent.
Example 5
40% of the soluble powder of the glufosinate-ammonium and 8% of the topramezone are prepared, and the raw material formula is shown in table 6.
TABLE 6
The 48% soluble powder of the glufosinate-ammonium and the topramezone is prepared by uniformly stirring and mixing the glufosinate-ammonium, the topramezone, the surfactant alkylbenzene sulfonate, the polyethylene glycol and the filler according to the proportion and carrying out superfine grinding by a jet mill.
Example 6
36% of arginate-ammonium and 6% of topramezone soluble granules are prepared, and the raw material formula is shown in table 7.
TABLE 7
| Component (A) | Proportioning of |
| Paraquat-ammonium phosphine | 36% of the folding hundred |
| Topramezone | 6% of the folded hundred |
| Surfactant alkyl sulfate | 3.5％ |
| Surfactant polycarboxylate | 4％ |
| Disintegrating agent ammonium sulfate | 5％ |
| Diatomite filler | Make up to 100% |
The preparation method comprises the steps of uniformly stirring and mixing the glufosinate-ammonium, the topramezone, the surfactant, the disintegrating agent and the filler according to the proportion, carrying out superfine grinding by a jet mill, adding 9% of water, kneading for 20 minutes by a kneader, extruding and granulating by an extrusion granulator, and drying at 60 ℃ for 30 minutes to obtain 42% soluble granules of the glufosinate-topramezone.
Example 7
The raw material formula of the 60% glufosinate-ammonium and 10% topramezone wettable powder is shown in table 8.
TABLE 8
| Component (A) | Proportioning of |
| Paraquat-ammonium phosphine | 60% of the folding hundred |
| Topramezone | 10% of the folding hundred |
| Surfactant polycarboxylate | 5％ |
| Polyethylene glycol as binder | 2％ |
| Filler kaolin | Make up to 100% |
The 70% wettable powder of the glufosinate-ammonium and the topramezone is prepared by uniformly stirring and mixing the glufosinate-ammonium, the topramezone, the surfactant, the polyethylene glycol and the filler according to the proportion and carrying out superfine grinding by a jet mill.
Example 8
The raw material formula of the 30% glufosinate-ammonium and 6% topramezone water dispersible granule is shown in table 9.
TABLE 9
| Component (A) | Proportioning of |
| Paraquat-ammonium phosphine | 30% of the folded hundred |
| Glyphosate | 6% of the folded hundred |
| Surfactant polycarboxylate | 3％ |
| Surfactant lignosulfonate | 3％ |
| Binder methylcellulose | 1％ |
| Filler kaolin | Make up to 100% |
The preparation method comprises the steps of uniformly stirring and mixing the glufosinate-ammonium, the topramezone, the surfactant, the binder and the filler according to the proportion, carrying out superfine grinding by a jet mill, adding 13% of water for kneading and granulating, adding into an extrusion granulator for extrusion and granulating, and drying at 60 ℃ to obtain 36% of glufosinate-topramezone water dispersible granule.
Comparative example 1
40% of arginate-ammonium +8% topramezone soluble powder (compared with example 5, without polyethylene glycol and kaolin) was prepared, and the raw material formulation is shown in table 10.
Table 10
| Component (A) | Proportioning of |
| Paraquat-ammonium phosphine | 40% of the folding hundred |
| Topramezone | 8% of the folding hundred |
| Surface active agentSex agent alkylbenzene sulfonate | 5％ |
| Diatomite filler | Make up to 100% |
The technical scheme is that the 48% soluble powder of the glufosinate-ammonium and the topramezone is prepared by uniformly stirring and mixing the glufosinate-ammonium, the topramezone, the surfactant alkylbenzene sulfonate and the filler according to the proportion and performing superfine grinding by a jet mill.
Comparative example 2
40% of glufosinate-ammonium and 8% of topramezone suspending agent (compared with example 3, without fatty alcohol polyoxyethylene ether) is prepared, and the raw material formula is shown in table 11.
TABLE 11
Adding the glufosinate-ammonium, the topramezone and the polycarboxylate into water, stirring at 180 revolutions per minute until the raw materials are wetted and dissolved, and sanding by a sand mill to obtain the 48% glufosinate-topramezone suspending agent.
Comparative example 3
40% of arginate-ammonium and 8% of mesotrione suspending agent (compared with example 3, the active ingredient topramezone is replaced by mesotrione, and the rest components are the same) is prepared, and the raw material formula is shown in table 12.
Table 12
| Component (A) | Proportioning of |
| Paraquat-ammonium phosphine | 40% of the folding hundred |
| Mesotrione | 8% of the folding hundred |
| Surfactant fatty alcohol polyoxyethylene ether | 4％ |
| Surfactant polycarboxylate | 4％ |
| Antifreezing agent propylene glycol | 5％ |
| Water and its preparation method | Make up to 100% |
Adding the glufosinate-ammonium, the mesotrione and the surfactant into water, stirring at 180 revolutions per minute until the raw materials are wetted and dissolved, and sanding by a sand mill to obtain the 48% glufosinate-mesotrione suspending agent.
Comparative example 4
40% of the glufosinate-ammonium and 8% of the cyclosulfamone suspending agent (compared with example 3, the active ingredient topramezone is replaced by cyclosulfamone, and the rest components are the same) are prepared, and the raw material formula is shown in table 13.
TABLE 13
| Component (A) | Proportioning of |
| Paraquat-ammonium phosphine | 40% of the folding hundred |
| Cyclosulphone ketone | 8% of the folding hundred |
| Surfactant fatty alcohol polyoxyethylene ether | 4％ |
| Surfactant polycarboxylate | 4％ |
| Antifreezing agent propylene glycol | 5％ |
| Water and its preparation method | Make up to 100% |
Adding the glufosinate, the cyclosulfamide and the surfactant into water, stirring at 180 revolutions per minute until the raw materials are wetted and dissolved, and sanding by a sand mill to obtain the 48% glufosinate-cyclosulfamide suspending agent.
Comparative example 5
40% of the arginate-ammonium and 8% of the isoxaflutole suspending agent (compared with example 3, the active ingredient topramezone is replaced by isoxaflutole, and the rest components are the same) is prepared, and the raw material formula is shown in table 14.
TABLE 14
| Component (A) | Proportioning of |
| Paraquat-ammonium phosphine | 40% of the folding hundred |
| Isoxazolidinone | 8% of the folding hundred |
| Surfactant fatty alcohol polyoxyethylene ether | 4％ |
| Surfactant polycarboxylate | 4％ |
| Antifreezing agent propylene glycol | 5％ |
| Water and its preparation method | Make up to 100% |
Adding the glufosinate-ammonium, the isoxaflutole and the surfactant into water, stirring at 180 revolutions per minute until the raw materials are wetted and dissolved, and sanding by a sand mill to obtain the 48% glufosinate-isoxaflutole suspending agent.
Example 9
The test aims to confirm the actual prevention effect of the compound preparation of the glufosinate-ammonium and the imazethapyr on weeds in corn fields, comprehensively evaluate the compound preparation of the glufosinate-ammonium and the topramezone, and provide a certain theoretical basis for the specific application of the next step. The test is performed with reference to GB/T17980-2000 pesticide field efficacy test guidelines.
1 materials and methods
1.1 reagents for test
The prevention and treatment agent is a compound preparation of the glufosinate-ammonium, the topramezone and the like, and the specific examples are shown in examples 2-8 and comparative examples 1-5.
The control agent was 10% aqueous glufosinate-ammonium (commercially available) and 30% topramezone suspension (commercially available).
1.2 subjects
Weeds in corn fields mainly comprise barnyard grass, green bristlegrass, crabgrass, purslane and acalypha australis, and perennial weeds mainly comprise erigeron breviscapus and herba polygoni avicularis. The weed coverage of each treatment district is 80% when the pesticide is applied, and the plant height is 15-30 cm.
1.3 design of experiments
The test was run with a total of 14 treatments and each was run with a blank Control (CK) treatment with 66 square meters per cell area, 3 replicates, 45 cells total. The cells of different treatments are arranged in a completely random block. The design process is shown in Table 15.
TABLE 15
| Process numbering | Treatment agent | Dosage of active ingredient (g/mu) |
| A | Example 2 | 25 |
| B | Example 3 | 25 |
| C | Example 4 | 25 |
| D | Example 5 | 25 |
| E | Example 6 | 25 |
| F | Example 7 | 25 |
| G | Example 8 | 25 |
| H | Comparative example 1 | 25 |
| I | Comparative example 2 | 25 |
| J | Comparative example 3 | 25 |
| K | Comparative example 4 | 25 |
| L | Comparative example 5 | 25 |
| M | 10% refined glufosinate-ammonium aqua (pharmaceutical control) | 25 |
| N | 30% topramezone suspension (control) | 4 |
| O | Blank (CK) | / |
1.4 test environmental conditions
The test site is the Anyi town in BaoYing county of Jiangsu province, the test field is wheat, the wheat stubble is higher, and the corn plant height is about 30 cm. Test Tian Deshi was flat, sandy loam.
Test weather: the weather is cloudy in the day of drug application, the highest temperature is 32 ℃, the lowest temperature is 24 ℃, and no wind exists. Rainy weather is present 5 days after the medicine.
1.5 test methods
The test was carried out in the morning of 7 months and 12 days in 2020, spraying was carried out using a backpack electric sprayer, a protective cover was installed, and directional spraying was carried out on weeds between corn rows, so that the liquid medicine was prevented from being sprayed to 30L/mu of each treatment water on corn as much as possible.
2 investigation method and drug efficacy evaluation method
The control effect of each treatment was examined 10d and 21d after the application of the drugs, and the type and number of weeds were recorded by selecting 0.5 square meter for each spot by a 3-spot sampling method. While the effect on corn was visually examined.
The results of the investigation are shown in Table 16 below.
Table 16
As shown in Table 16, compared with the comparative example and the control medicament, the compound preparation of the clomazone and the topramezone in different examples has obviously improved control effects on annual and perennial weeds in fields, the control effects on annual and perennial weeds in fields are higher than 80% in 10 days, and the control effects in 21 days are higher than 80%.
In comparative examples 1 and 2, although the combination of the glufosinate-ammonium and the topramezone is adopted, the selection of the surfactant, the filler and the like is unreasonable, the prevention effect is lower than 75% in 10 days and 21 days, the effects are obviously lower than those of the corresponding examples 5 and 3, and the components and the proportions selected in the examples are more reasonable.
Compared with the example 3, the comparative example 4 and the comparative example 5, the effective components topramezone in the example 3 are respectively replaced by mesotrione, cyclosulfamuron and isoxaflutole with similar structures and action modes, and the prevention effect is lower than 70% in 10 days and 21 days, which indicates that the compounding of the three and the glufosinate-ammonium is not obvious as the compounding synergy of the glufosinate-ammonium and the topramezone.
The treated corns grow normally and are safe to corns.
The above embodiments are provided to illustrate the technical concept and features of the present invention and are intended to enable those skilled in the art to understand the content of the present invention and implement the same, and are not intended to limit the scope of the present invention. All equivalent changes or modifications made in accordance with the spirit of the present invention should be construed to be included in the scope of the present invention.
Claims (1)
1. A compound composition of glufosinate-ammonium and topramezone is characterized in that: the compound composition is a suspending agent, and the formula of the suspending agent comprises the following components in percentage by mass:
40% of glufosinate-ammonium;
topramezone 8%;
4% of fatty alcohol polyoxyethylene ether;
4% of polycarboxylate;
propylene glycol 5%;
the water is filled up to 100%.
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| BR112020002666A2 (en) * | 2017-08-09 | 2020-07-28 | Basf Se | use of herbicide mixture, pesticide mixture, pesticide composition and vegetation control method |
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