CN115089688A - Multifunctional foot bath liquid and preparation method thereof - Google Patents

Multifunctional foot bath liquid and preparation method thereof Download PDF

Info

Publication number
CN115089688A
CN115089688A CN202210862188.5A CN202210862188A CN115089688A CN 115089688 A CN115089688 A CN 115089688A CN 202210862188 A CN202210862188 A CN 202210862188A CN 115089688 A CN115089688 A CN 115089688A
Authority
CN
China
Prior art keywords
parts
extract
treatment
foot bath
water
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
CN202210862188.5A
Other languages
Chinese (zh)
Inventor
李湘丹
张德金
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Deciphering Truth Network Technology Shanghai Co ltd
Original Assignee
Deciphering Truth Network Technology Shanghai Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Deciphering Truth Network Technology Shanghai Co ltd filed Critical Deciphering Truth Network Technology Shanghai Co ltd
Priority to CN202210862188.5A priority Critical patent/CN115089688A/en
Publication of CN115089688A publication Critical patent/CN115089688A/en
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/41Crassulaceae (Stonecrop family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236Ligusticum (licorice-root)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282Artemisia, e.g. wormwood or sagebrush
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/39Convolvulaceae (Morning-glory family), e.g. bindweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/43Cuscutaceae (Dodder family), e.g. Cuscuta epithymum or greater dodder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/482Cassia, e.g. golden shower tree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537Salvia (sage)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/72Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
    • A61K36/725Ziziphus, e.g. jujube
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9068Zingiber, e.g. garden ginger
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/15Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Dermatology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention relates to a multifunctional foot bath lotion and a preparation method thereof; the multifunctional foot bath liquid comprises the following components in parts by weight: 15-30 parts of rhodiola rosea extract, 20-40 parts of raspberry extract, 20-40 parts of semen cuscutae extract, 12-25 parts of salvia miltiorrhiza extract, 15-30 parts of angelica sinensis extract, 15-30 parts of ligusticum wallichii extract, 30-50 parts of folium artemisiae argyi extract, 20-40 parts of ginger extract, 5-12 parts of borneol extract, 5-12 parts of liquorice extract, 5-12 parts of folium sennae extract, 3-10 parts of spina date seed extract and a proper amount of water; the multifunctional foot bath bag has the effects of benefiting qi, strengthening exterior, dispelling cold, removing dampness and improving body immunity, and is suitable for typical hypoimmunity people with spleen-kidney yang deficiency, qi weakness, asthenia, emaciation, short breath, hypodynamia, listlessness and the like; the invention dissolves the effective components of the traditional Chinese medicine into water, achieves the purposes of health care and body building through the percutaneous absorption of the traditional Chinese medicine liquid, overcomes the pain and toxic and side effects of oral traditional Chinese medicine, can be quickly integrated with warm water, and is more convenient to use compared with a foot bath bag.

Description

Multifunctional foot bath lotion and preparation method thereof
Technical Field
The invention relates to the field of traditional Chinese medicine compositions, in particular to a multifunctional foot bath liquid and a preparation method thereof.
Background
With the development of society and the acceleration of life rhythm, the pressure from society, work, life and the like is increased, the need of people for strengthening body health care is urgent, and when the immunity of a human body is low and can not resist the balance of external factors, the physiological function can be out of balance to generate diseases, in particular to various diseases caused by liver and kidney, rheumatism, yin deficiency and low immunity.
The traditional Chinese medicine foot bath therapy is based on the traditional Chinese medicine theory, adopts traditional Chinese medicine for external foot bath, quickly enables medicine ions to enter blood through skin mucous membrane absorption and warm fumigation of medicine liquid, enables medicine properties to reach viscera through acupuncture points, stimulates acupuncture points of the whole body, dredges channel qi and regulates qi and blood, and the traditional Chinese medicine theory considers that the traditional Chinese medicine can achieve the effects of dredging channel qi, regulating qi and blood and regulating the functions of viscera through stimulating the acupuncture points.
Disclosure of Invention
The invention aims to provide a multifunctional foot bath bag and a preparation method thereof aiming at the defects in the prior art.
In order to achieve the purpose, the invention adopts the technical scheme that:
the invention provides a multifunctional foot bath liquid, which comprises the following components in parts by weight: 15-30 parts of rhodiola rosea extract, 20-40 parts of raspberry extract, 20-40 parts of semen cuscutae extract, 12-25 parts of salvia miltiorrhiza extract, 15-30 parts of angelica extract, 15-30 parts of ligusticum wallichii extract, 30-50 parts of folium artemisiae argyi extract, 20-40 parts of ginger extract, 5-12 parts of borneol extract, 5-12 parts of liquorice extract, 5-12 parts of senna leaf extract, 3-10 parts of spina date seed extract and a proper amount of water.
The second aspect of the invention provides a preparation method of the multifunctional foot bath liquid, which comprises the following steps: weighing rhodiola rosea, raspberry, semen cuscutae, salvia miltiorrhiza, angelica sinensis, ligusticum wallichii, folium artemisiae argyi, ginger, borneol, liquorice, senna leaves and spina date seeds in sequence according to parts by weight, respectively carrying out crushing treatment and water extraction treatment, then carrying out mixing treatment, concentration treatment and sterilization treatment in sequence, and then bagging to obtain the multifunctional foot bath liquid.
Preferably, the pulverization treatment comprises: pulverizing with a pulverizer, and sieving with 60 mesh sieve.
Preferably, the temperature of the water extraction treatment is 60-80 ℃, and the ratio of material to liquid is 1: (4-7), the extraction times are 3-5.
Preferably, the mixing treatment is ultrasonic mixing treatment, and the time of the ultrasonic mixing treatment is 10-30 minutes.
Preferably, the concentration treatment is to concentrate the mixture to 30-40 times by adopting a multi-effect vacuum concentration device.
Preferably, the sterilization treatment is to adopt pasteurization and then cool the mixture to 30-40 ℃.
By adopting the technical scheme, compared with the prior art, the invention has the following technical effects:
the multifunctional foot bath bag has the effects of benefiting qi, consolidating exterior, dispelling cold, removing dampness and improving body immunity, is suitable for typical hypoimmunity people with spleen-kidney yang deficiency, qi weakness, asthenia, emaciation, short breath, hypodynamia, listlessness and the like, and has obvious effect after use; the invention utilizes the principle of treating internal diseases by external therapy, dissolves the active ingredients of the traditional Chinese medicines into water, achieves the purposes of health care, health preservation, disease treatment and body building by the transdermal absorption of the traditional Chinese medicine liquid by feet, overcomes the pain and toxic and side effects of oral traditional Chinese medicines, can quickly integrate the foot bath liquid with warm water, and is more convenient to use compared with a foot bath bag.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
It should be noted that the embodiments and features of the embodiments may be combined with each other without conflict.
The present invention is further illustrated by the following examples, which are not to be construed as limiting the invention.
Example 1
The embodiment provides a preparation method of multifunctional foot bath liquid, which comprises the following steps:
weighing 22 parts of rhodiola rosea, 30 parts of raspberry, 28 parts of semen cuscutae, 20 parts of salvia miltiorrhiza, 23 parts of angelica sinensis, 25 parts of ligusticum wallichii, 40 parts of folium artemisiae argyi, 28 parts of ginger, 8 parts of borneol, 8 parts of liquorice, 8 parts of folium sennae and 6 parts of spina date seeds in sequence, crushing by a crusher, sieving by a 60-mesh sieve, performing water extraction treatment for 4 times at the temperature of 70 ℃ and the material-liquid ratio of 1:5, performing ultrasonic mixing treatment on different extracting solutions for 20 minutes, concentrating to 35 times by a multi-effect vacuum concentration device, performing pasteurization, cooling to 35 ℃ and bagging.
Example 2
The embodiment provides another preparation method of a multifunctional foot bath liquid, which comprises the following steps:
weighing 20 parts of rhodiola rosea, 25 parts of raspberry, 25 parts of semen cuscutae, 18 parts of salvia miltiorrhiza, 21 parts of angelica, 21 parts of ligusticum wallichii, 38 parts of folium artemisiae argyi, 26 parts of ginger, 5 parts of borneol, 5 parts of liquorice, 5 parts of folium sennae and 4 parts of spina date seeds in sequence, crushing by a crusher, sieving by a 60-mesh sieve, performing water extraction treatment for 5 times at the temperature of 65 ℃ and the material-liquid ratio of 1:4, performing ultrasonic mixing treatment on different extracting solutions for 30 minutes, concentrating to 32 times by a multi-effect vacuum concentration device, performing pasteurization, cooling to 30 ℃, and bagging.
Example 3
The embodiment provides another preparation method of a multifunctional foot bath liquid, which comprises the following steps:
weighing 28 parts of rhodiola rosea, 35 parts of raspberry, 33 parts of semen cuscutae, 24 parts of salvia miltiorrhiza, 26 parts of angelica sinensis, 26 parts of ligusticum wallichii, 42 parts of folium artemisiae argyi, 31 parts of ginger, 10 parts of borneol, 10 parts of liquorice, 10 parts of folium sennae and 9 parts of spina date seeds in sequence, crushing by a crusher, sieving by a 60-mesh sieve, performing water extraction treatment for 3 times at the temperature of 80 ℃ and the material-liquid ratio of 1:7, performing ultrasonic mixing treatment on different extracting solutions for 10 minutes, concentrating to 38 times by a multi-effect vacuum concentration device, performing pasteurization, cooling to 40 ℃ and bagging.
Application examples
The foot bath liquid prepared by the preparation method of the embodiment 1-3 is respectively used for the curative effect test of relieving insomnia, the curative effect test of improving immunity and the curative effect test of tonifying kidney.
1. Insomnia-relieving efficacy test
Selecting an object: screening 150 clinical volunteers with insomnia, 75 male volunteers and 75 female volunteers with age of 30-50 years, disease course of 2-8 months and sleep time of 4-6 hours, and intermittently using hypnotic to fall asleep, but not dependent, and clinically diagnosing as mild insomnia.
Diagnostic criteria: referring to Chinese Classification scheme and diagnosis Standard of mental disorders, the clinical manifestations of the insomnia are difficulty in falling asleep, easy to wake up, difficulty in falling asleep again after waking up, fatigue, sleepiness and discomfort in daytime, which occur more than 3 times per week and last for more than 1 month, the insomnia causes obvious distress, decreased mental activity efficiency, decreased memory and the like, and the insomnia caused by factors such as brain, trunk or mental diseases is excluded.
The therapeutic effect judgment standard is as follows: healing, normally falling asleep, sleeping for more than 6h every night, and not waking up midway; obvious effect-fall asleep normally, sleep for more than 4h every night, wake up occasionally in midway; improvement: the symptoms are improved, and the sleep time is increased by <3h compared with the prior sleep time; and (4) invalidation: the insomnia symptom is not improved or aggravated.
150 patients were randomly and evenly divided into 3 groups of 50 patients, and the foot bath solutions prepared in examples 1-3 were respectively used in the following methods: taking a bag of foot bath liquid, unpacking a plastic outer packaging bag, pouring the foot bath liquid into a foot soaking barrel filled with 5L of boiled water, steaming feet for 15-20 minutes by steam, adding a proper amount of cold water and stirring, cooling the water to about 45 ℃, statically soaking feet for 25min, adding hot water at any time to keep the water temperature at about 45 ℃, soaking feet once a day, continuously soaking feet for 7 days as 1 treatment course, and observing 4 treatment courses altogether, wherein the curative effect is shown in table 1.
TABLE 1
Group of Number of examples Recovery/recovery Significant effects/examples Improvement/example Invalid/example Total effective rate/%)
Example 1 50 40 6 3 1 98
Example 2 50 36 5 5 4 92
Example 3 50 38 4 6 2 96
As can be seen from the table 1, the foot bath liquid has obvious curative effect on mild insomnia.
2. Immunity-enhancing therapeutic effect test
Selecting an object: 150 volunteers with poor immunity and susceptible to weak cold are selected, and the age is 25-49 years old.
The therapeutic effect judgment standard is as follows: the traditional Chinese medicine has obvious effect, and after treatment, the main symptoms disappear completely, and the clinical cure is realized; effective, the symptom is better than before treatment; no effect, no improvement in clinical signs.
The 150 patients were randomly and evenly divided into 3 groups of 50 patients, and the foot bath liquids prepared in examples 1-3 were respectively used, and the application method of the foot bath liquid was: taking a bag of foot bath liquid, unpacking a plastic outer packaging bag, pouring the foot bath liquid into a foot soaking barrel filled with 5L of boiled water, steaming feet for 15-20 minutes by steam, adding a proper amount of cold water and stirring, cooling the water to about 45 ℃, statically soaking feet for 25min, adding hot water at any time to keep the water temperature at about 45 ℃, soaking feet once a day, continuously soaking feet for 7 days as 1 treatment course, and observing 4 treatment courses altogether, wherein the curative effect is shown in table 2.
TABLE 2
Group of Number of examples Significant effects/examples Effective/example Invalid/example Total effective rate/%)
Example 1 50 40 8 2 96
Example 2 50 35 11 4 92
Example 3 50 38 9 3 94
As can be seen from Table 2, the foot bath liquid of the present invention has significant efficacy in enhancing immunity.
3. Kidney invigorating curative effect test (female)
Selecting an object: 160 cases of hypo-ovarian-reserve-function-simulating IVF-ET pregnancy-assisting patients are selected as research objects, and a design scheme of random parallel contrast observation is adopted on the premise that the patients know to voluntarily, and the experimental results are randomly divided into 80 cases of an observation group and 80 cases of a contrast group; the patients in the observation group are 34-42 years old and 4-10 years old for infertility; the age of the patients in the control group is 33-42 years, and the infertility period is 5-10 years; the age and the sterility age of two groups of patients are compared, and the difference has no statistical significance; the treatment protocol received informed consent from the patient, in compliance with the approval of the medical ethics committee.
Diagnostic criteria: the traditional Chinese medicine diagnosis establishes the symptoms of kidney deficiency, spleen deficiency, liver depression and blood deficiency according to the relevant contents in the guiding principles of clinical research of new traditional Chinese medicines. The main symptoms are: firstly, the non-contraception is not pregnant for more than 1 year; soreness and weakness of waist and knees; and thirdly, the quantity is small, the color is light and the quality is thin in the later period of menstruation. The secondary symptoms are as follows: dizziness and tinnitus; ② hyposexuality; ③ insomnia and amnesia; fourthly, palpitation and insomnia; depression and oliguria. Tongue pulse: a pale tongue with thin and white coating and a deep, thready and weak pulse. Has all the principal and secondary evidences and two or more secondary evidences.
The treatment method comprises the following steps: the control group was pretreated by conventional method, and administered orally for 28 days as one treatment course for 3 treatment courses. The observation group adopts the foot bath liquid prepared by the preparation method of the embodiment 1 for treatment, and the using method of the foot bath liquid comprises the following steps: taking a bag of foot bath liquid, unpacking a plastic outer packaging bag, pouring the foot bath liquid into a foot soaking barrel filled with 5L of boiled water, steaming feet for 15-20 minutes by steam, adding a proper amount of cold water and stirring to reduce the water temperature to about 45 ℃, statically soaking feet for 25min, adding hot water at any time to keep the water temperature at about 45 ℃, soaking feet once every day, taking a menstrual cycle as a treatment course, and observing for 3 treatment courses.
Observation indexes are as follows: calculating the ovum rate, performing transvaginal ultrasonography on the patient on the 2 nd day of menstrual menstruation, and measuring the number of antral follicles of 2-9mm and the ovary volume of the patient;
the egg yield is equal to the number of obtained eggs/the number of follicles with the diameter of more than or equal to 14mm in both ovaries on HCG day multiplied by 100 percent.
The results are shown in Table 3.
TABLE 3
Figure BDA0003756464010000051
After two groups of patients are treated, the observed group has obviously increased antral follicle number and ovary volume, and has significant difference compared with a control group through statistical treatment.
4. Kidney invigorating curative effect test (Male)
Selecting an object: 180 male clinical volunteers with kidney deficiency are screened, the age is 30-50 years, and the volunteers are divided into three types, namely spleen and kidney qi deficiency, liver and kidney yin deficiency and spleen and kidney deficiency according to Chinese medicine typing.
Diagnostic criteria: the main symptoms of qi deficiency of spleen and kidney are frequent micturition, dribbling, listlessness, pale tongue, white fur and thready and weak pulse; the main symptoms of liver-kidney yin deficiency are soreness and weakness of waist and knees, hypochondriac pain, dizziness and tinnitus; the deficiency of both the spleen and kidney clinically manifests as the failure of the rectum to slip and collapse, the anus feeling of tenesmus, dizziness, tinnitus, lassitude, shortness of breath, soreness and weakness of the waist and knees, frequent micturition at night, loose stool or dry stool with difficulty in urination, pale tongue and deep and weak pulse.
The therapeutic effect judgment standard is as follows: the medicine has obvious effect, and after treatment, the main symptoms disappear completely; effective, the symptom is better than before treatment; no effect, no improvement in clinical signs.
180 patients were randomly and evenly divided into 3 groups of 60 patients, and the foot bath solutions prepared in examples 1-3 were used respectively, and the application method of the foot bath solution was: taking a bag of foot bath liquid, unpacking a plastic outer packaging bag, pouring the foot bath liquid into a foot soaking barrel filled with 5L of boiled water, steaming feet for 15-20 minutes by steam, adding a proper amount of cold water and stirring, cooling the water to about 45 ℃, statically soaking feet for 25min, adding hot water at any time to keep the water temperature at about 45 ℃, soaking feet once a day, continuously soaking feet for 7 days as 1 treatment course, and observing 4 treatment courses altogether, wherein the curative effect is shown in table 4.
TABLE 4
Figure BDA0003756464010000061
In conclusion, the multifunctional foot bath bag has the effects of benefiting qi, strengthening exterior, dispelling cold, removing dampness and improving body immunity, is suitable for typical people with low immunity, such as spleen-kidney yang deficiency, qi weakness, consumptive disease, emaciation, short breath, hypodynamia, listlessness and the like, and has obvious effect after use; the invention utilizes the principle of treating internal diseases by external therapy, dissolves the active ingredients of the traditional Chinese medicines into water, achieves the purposes of health care, health preservation, disease treatment and body building by percutaneous absorption of the traditional Chinese medicine liquid by feet, overcomes the pain and toxic and side effects of oral traditional Chinese medicines, can quickly integrate the foot bath liquid with warm water, and is more convenient to use compared with a foot bath bag.
While the invention has been described with reference to a preferred embodiment, it will be understood by those skilled in the art that various changes in form and detail may be made therein without departing from the spirit and scope of the invention.

Claims (7)

1. The multifunctional foot bath liquid is characterized by comprising the following components in parts by weight: 15-30 parts of rhodiola rosea extract, 20-40 parts of raspberry extract, 20-40 parts of semen cuscutae extract, 12-25 parts of salvia miltiorrhiza extract, 15-30 parts of angelica extract, 15-30 parts of ligusticum wallichii extract, 30-50 parts of folium artemisiae argyi extract, 20-40 parts of ginger extract, 5-12 parts of borneol extract, 5-12 parts of liquorice extract, 5-12 parts of folium sennae extract, 3-10 parts of spina date seed extract and a proper amount of water.
2. The preparation method of the multifunctional foot bath liquid as claimed in claim 1, characterized by comprising the steps of: weighing rhodiola rosea, raspberry, semen cuscutae, salvia miltiorrhiza, angelica sinensis, ligusticum wallichii, folium artemisiae argyi, ginger, borneol, liquorice, senna leaves and spina date seeds in sequence according to parts by weight, respectively carrying out crushing treatment and water extraction treatment, then carrying out mixing treatment, concentration treatment and sterilization treatment in sequence, and then bagging to obtain the multifunctional foot bath liquid.
3. The production method according to claim 2, wherein the pulverization treatment comprises: pulverizing with a pulverizer, and sieving with 60 mesh sieve.
4. The preparation method according to claim 2, wherein the temperature of the water extraction treatment is 60-80 ℃, and the ratio of feed to liquid is 1: (4-7), the extraction times are 3-5.
5. The production method according to claim 2, wherein the mixing treatment is an ultrasonic mixing treatment, and the time of the ultrasonic mixing treatment is 10 to 30 minutes.
6. The preparation method according to claim 2, wherein the concentration treatment is to 30 to 40 times by using a multi-effect vacuum concentration device.
7. The method of claim 2, wherein the sterilization treatment is pasteurization followed by cooling to 30-40 ℃.
CN202210862188.5A 2022-07-20 2022-07-20 Multifunctional foot bath liquid and preparation method thereof Withdrawn CN115089688A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202210862188.5A CN115089688A (en) 2022-07-20 2022-07-20 Multifunctional foot bath liquid and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202210862188.5A CN115089688A (en) 2022-07-20 2022-07-20 Multifunctional foot bath liquid and preparation method thereof

Publications (1)

Publication Number Publication Date
CN115089688A true CN115089688A (en) 2022-09-23

Family

ID=83299426

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202210862188.5A Withdrawn CN115089688A (en) 2022-07-20 2022-07-20 Multifunctional foot bath liquid and preparation method thereof

Country Status (1)

Country Link
CN (1) CN115089688A (en)

Similar Documents

Publication Publication Date Title
CN102293874B (en) Multifunctional medicinal pillow and preparation method thereof
CN103751310B (en) A kind of traditional Chinese medicine for external application and its preparation method treating fascitis
CN100534509C (en) Chinese-medicinal suppository for treating lumbar vertebrae disease and preparation method thereof
CN1330352C (en) Health care wine and preparation method
CN104474341B (en) A kind of pharmaceutical composition for the treatment of hyperkinetic syndrome
CN101284077B (en) Chinese medicine composition for curing male oligoasthenospermia
CN104706953A (en) Traditional Chinese medicine preparation for treating chronic cervicitis
CN115089688A (en) Multifunctional foot bath liquid and preparation method thereof
CN100467054C (en) Chinese-medicinal suppository for treating cervical spondylosis and its preparation
CN104383453B (en) Treat the Chinese medicine of craniocerebral injury manic disorder
CN106860514A (en) A kind of external medicine composition, its extract, its preparation and its application
CN112121079A (en) Acupuncture needle capable of enhancing pain relieving efficacy and preparation method and application thereof
CN104971204A (en) Kidney-tonifying and resuscitation-inducing pill and medicinal strip cooperating with acupuncture for treating neurological tinnitus
CN104940304A (en) Application for treating childhood asthma in remission phase through iontophoresis
CN103202964A (en) Brain-improving and mind-calming medicinal liquor
CN104524133B (en) A kind of Chinese medicine composition of the solid born of the same parents&#39; beauty treatment of kidney tonifying
CN102579757B (en) Anti-aging Chinese medicine composition in separation medicine and moxibustion umbilicus mode
CN104971308A (en) Traditional Chinese medicine composition for treating chronic prostatitis
CN104707031A (en) Traditional Chinese medicine composition for treating senile osteoporosis and preparation method thereof
CN105521391A (en) Traditional Chinese medicine for tonifying liver and kidney and for strengthening bones and muscles and preparation method of traditional Chinese medicine
CN112316091A (en) Traditional Chinese medicine composition for treating insomnia and foot bath solid preparation thereof
CN104623127A (en) Medicine for treating tinea pedis and preparation method thereof
CN112972611A (en) Pharmaceutical composition for treating hemolytic anemia and application thereof
CN103690644A (en) Traditional Chinese medicine preparation for promoting fracture rehabilitation
CN111686232A (en) External ointment for treating insomnia and application thereof

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
WW01 Invention patent application withdrawn after publication

Application publication date: 20220923

WW01 Invention patent application withdrawn after publication