CN115071040B - Preparation device and preparation method of artificial blood vessel with microstructure on inner surface - Google Patents
Preparation device and preparation method of artificial blood vessel with microstructure on inner surface Download PDFInfo
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- CN115071040B CN115071040B CN202210738869.0A CN202210738869A CN115071040B CN 115071040 B CN115071040 B CN 115071040B CN 202210738869 A CN202210738869 A CN 202210738869A CN 115071040 B CN115071040 B CN 115071040B
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- hydraulic rod
- core column
- shaped core
- silica gel
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- 210000004204 blood vessel Anatomy 0.000 title claims abstract description 34
- 239000002473 artificial blood Substances 0.000 title claims abstract description 31
- 238000002360 preparation method Methods 0.000 title claims abstract description 17
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims abstract description 61
- 239000000741 silica gel Substances 0.000 claims abstract description 61
- 229910002027 silica gel Inorganic materials 0.000 claims abstract description 61
- 239000007788 liquid Substances 0.000 claims abstract description 44
- 238000000465 moulding Methods 0.000 claims abstract description 23
- 239000000463 material Substances 0.000 claims abstract description 22
- 238000005086 pumping Methods 0.000 claims abstract description 8
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 45
- 238000004321 preservation Methods 0.000 claims description 23
- 230000001681 protective effect Effects 0.000 claims description 14
- 238000007789 sealing Methods 0.000 claims description 7
- 238000000034 method Methods 0.000 claims description 5
- 230000002792 vascular Effects 0.000 claims description 3
- 239000006052 feed supplement Substances 0.000 claims description 2
- 238000007493 shaping process Methods 0.000 claims description 2
- 230000004048 modification Effects 0.000 abstract description 3
- 238000012986 modification Methods 0.000 abstract description 3
- 239000003921 oil Substances 0.000 description 22
- 238000010586 diagram Methods 0.000 description 5
- 239000002994 raw material Substances 0.000 description 5
- 208000024172 Cardiovascular disease Diseases 0.000 description 3
- 241000282414 Homo sapiens Species 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 238000009413 insulation Methods 0.000 description 3
- 238000002715 modification method Methods 0.000 description 2
- 230000000149 penetrating effect Effects 0.000 description 2
- 238000007711 solidification Methods 0.000 description 2
- 230000008023 solidification Effects 0.000 description 2
- 208000005189 Embolism Diseases 0.000 description 1
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 1
- 208000007536 Thrombosis Diseases 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000001133 acceleration Effects 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 230000015271 coagulation Effects 0.000 description 1
- 238000005345 coagulation Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000037213 diet Effects 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 239000007943 implant Substances 0.000 description 1
- 230000001788 irregular Effects 0.000 description 1
- 230000033764 rhythmic process Effects 0.000 description 1
- 229910052710 silicon Inorganic materials 0.000 description 1
- 239000010703 silicon Substances 0.000 description 1
- 230000001502 supplementing effect Effects 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C45/00—Injection moulding, i.e. forcing the required volume of moulding material through a nozzle into a closed mould; Apparatus therefor
- B29C45/03—Injection moulding apparatus
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C45/00—Injection moulding, i.e. forcing the required volume of moulding material through a nozzle into a closed mould; Apparatus therefor
- B29C45/17—Component parts, details or accessories; Auxiliary operations
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C45/00—Injection moulding, i.e. forcing the required volume of moulding material through a nozzle into a closed mould; Apparatus therefor
- B29C45/17—Component parts, details or accessories; Auxiliary operations
- B29C45/40—Removing or ejecting moulded articles
- B29C45/4005—Ejector constructions; Ejector operating mechanisms
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C45/00—Injection moulding, i.e. forcing the required volume of moulding material through a nozzle into a closed mould; Apparatus therefor
- B29C45/17—Component parts, details or accessories; Auxiliary operations
- B29C2045/1784—Component parts, details or accessories not otherwise provided for; Auxiliary operations not otherwise provided for
Abstract
The invention belongs to the technical field of material surface modification, and particularly relates to a preparation device and a preparation method of an artificial blood vessel with a microstructure on the inner surface. The invention comprises a bottom plate, a storage box and a forming assembly; the storage box is communicated with the forming assembly through the material drawing assembly; the molding assembly comprises a molding cavity, a mandrel, a first hydraulic rod and a second hydraulic rod which are arranged on the mandrel, a first arc-shaped core column sheet connected with the telescopic end of the first hydraulic rod, and a second arc-shaped core column sheet connected with the telescopic end of the second hydraulic rod; according to the invention, the first arc-shaped core column piece and the second arc-shaped core column piece are respectively ejected by the first hydraulic rod and the second hydraulic rod, so that the first arc-shaped core column piece and the second arc-shaped core column piece are combined to be cylindrical, the liquid silica gel is pressed into the forming cavity by the material pumping assembly, and the microstructure on the outer surfaces of the first arc-shaped core column piece and the second arc-shaped core column piece is copied to the inner wall of the artificial blood vessel after the liquid silica gel is solidified to form the silica gel tube, so that the compatibility of the artificial blood vessel can be effectively improved.
Description
Technical Field
The invention belongs to the technical field of material surface modification, and particularly relates to a preparation device of an artificial blood vessel with a microstructure on the inner surface.
Background
In modern society, with the acceleration of life rhythm and irregular diet, cardiovascular diseases have become a large killer threatening human health, and are important causes of high mortality of human beings. Vascular reconstruction surgery is an effective method for treating cardiovascular diseases, since autologous blood vessels have the advantages of good biocompatibility, immunity, antigenicity and the like, most of autologous blood vessels are used as substitutes, but the sources of the autologous blood vessels are limited, so that artificial blood vessels become a good choice for treating cardiovascular diseases, silica gel is widely used in the field of biomedical materials due to good biocompatibility, excellent durability, ageing resistance and the like, and when the silica gel is used as an implant material to be placed in a human body for a long time, the problems of coagulation, thrombus and the like are easily caused to cause embolism, life threatening safety is caused, and in order to improve the problems, many students adopt various surface modification methods to improve the blood compatibility problem of the artificial blood vessels.
At present, a surface modification method adopts more laser to prepare microstructures on the surface of an artificial blood vessel, but the method is always limited to processing microstructures on a plane, and cannot be processed on the inner side of a pipeline of the artificial blood vessel, so that the efficiency is low and the effect is poor; therefore, there is a need to develop a device and a method for preparing an artificial blood vessel with a microstructure on the inner surface, which can prepare the microstructure on the inner side of the artificial blood vessel with high efficiency and can effectively improve the compatibility.
Disclosure of Invention
The invention aims to overcome the defects that microstructures cannot be prepared on the inner side of an artificial blood vessel, the efficiency is low and the effect is poor in the prior art, and provides a preparation device and a preparation method for an artificial blood vessel with microstructures on the inner surface, wherein the microstructures can be prepared on the inner surface of the artificial blood vessel, the efficiency is high, and the compatibility can be effectively improved.
The technical scheme adopted for solving the technical problems is as follows:
the utility model provides a preparation facilities of vascular prosthesis that interior surface has microstructure which characterized in that: comprises a bottom plate, a storage box and a forming assembly, wherein the storage box and the forming assembly are arranged on the bottom plate; the material storage box is communicated with the forming assembly through a material pumping assembly; the molding assembly comprises a molding barrel, a mandrel vertically arranged at the center of the molding barrel, a first hydraulic rod and a second hydraulic rod which are arranged on the mandrel, a first arc-shaped core column sheet connected with the telescopic end of the first hydraulic rod, and a second arc-shaped core column sheet connected with the telescopic end of the second hydraulic rod; when the telescopic rod of the first hydraulic rod and the telescopic rod of the second hydraulic rod are both ejected, the first arc-shaped core column piece and the second arc-shaped core column piece are combined to be cylindrical, and a forming cavity is formed among the outer wall of the first arc-shaped core column piece, the outer wall of the second arc-shaped core column piece and the inner wall of the forming barrel; when the telescopic rod of the first hydraulic rod and the telescopic rod of the second hydraulic rod are sequentially contracted, the connection part of the first arc-shaped core column sheet and the second arc-shaped core column sheet is in a step shape.
Further, a through hole is formed in the center of the mandrel, and a sealing ring and a sealing cover are arranged at the top end of the mandrel.
Further, the oil inlet and the oil outlet of the first hydraulic rod and the oil inlet and the oil outlet of the second hydraulic rod are communicated with the through hole in the center of the mandrel, the oil inlet and the oil outlet of the first hydraulic rod are positioned above the oil inlet and the oil outlet of the second hydraulic rod, and the first hydraulic rod and the second hydraulic rod are respectively provided with two parts; the first hydraulic rod, the second hydraulic rod and the mandrel are arranged in a pairwise perpendicular mode.
Further, the material pumping assembly comprises a material feeding pipe; one end of the feeding pipe is communicated with the storage box, and the other end of the feeding pipe is communicated with the forming cavity; the feeding pipe is provided with a water pump for extracting raw materials and a flow control valve for controlling the conveying speed of the raw materials.
Further, the molding assembly further includes a hydraulic pump mounted on the base plate; the bottom of the mandrel is connected with the hydraulic pump through an oil pipe.
Further, a heat-insulating barrel is sleeved outside the forming barrel, a heat-insulating cavity is formed between the inner wall of the heat-insulating barrel and the outer wall of the forming barrel, and a water inlet pipe and a water outlet pipe which are communicated with the heat-insulating cavity are formed in the heat-insulating barrel.
Further, the hydraulic pump is provided with the protective housing outward, the shaping bucket with the thermal-insulation barrel is all fixed the top of protective housing, the dabber runs through the protective housing just with protective housing fixed connection.
Further, a feed supplement port is formed in the top end of the storage box.
Further, an upper end cover is arranged at the top end of the heat preservation barrel, an exhaust hole is arranged on the upper end cover, and the exhaust hole is positioned above the forming cavity.
A method of preparing an artificial blood vessel having a microstructure on its inner surface, using the apparatus of claim 5, comprising the steps of:
s1, starting a hydraulic pump to enable a telescopic rod of a first hydraulic rod and a telescopic rod of a second hydraulic rod to extend out in sequence, wherein a first arc-shaped core column sheet and a second arc-shaped core column sheet are combined to form a cylinder;
s2, a water pump is turned on, liquid silica gel is conveyed into a forming cavity from a storage box, a flow control valve is turned on when the liquid silica gel in the forming cavity reaches a certain height, the flow rate of the liquid silica gel is slowed down, and the water pump is turned off immediately when the liquid silica gel is filled in the forming cavity;
s3, after the liquid silica gel is solidified into a silica gel tube, the hydraulic pump is opened again, the through hole in the center of the mandrel is gradually changed into a vacuum state from top to bottom, so that the first hydraulic rod and the second hydraulic rod sequentially drive the first arc-shaped core column sheet and the second arc-shaped core column sheet to shrink, demoulding is completed, and the whole silica gel tube is taken out.
The preparation device and the preparation method of the artificial blood vessel with the microstructure on the inner surface have the beneficial effects that:
1. according to the invention, the first arc-shaped core column piece and the second arc-shaped core column piece are respectively ejected by the first hydraulic rod and the second hydraulic rod, so that the first arc-shaped core column piece and the second arc-shaped core column piece are combined to be cylindrical, the liquid silica gel is pressed into the forming cavity by the material pumping assembly, and the microstructure on the outer surfaces of the first core column piece and the second core column piece is copied to the inner wall of the artificial blood vessel after the liquid silica gel is solidified to form the silica gel tube, so that the compatibility of the artificial blood vessel can be effectively improved.
2. According to the invention, the first core column piece and the second core column piece are respectively driven to shrink inwards by the first hydraulic rod and the second hydraulic rod, so that the complete demolding of the artificial blood vessel can be easily realized, and the artificial blood vessel demolding device is simple in structure and high in efficiency.
Drawings
The invention will be described in further detail with reference to the drawings and the detailed description.
FIG. 1 is an overall block diagram of an embodiment of the present invention;
FIG. 2 is a partial block diagram of an embodiment of the present invention;
FIG. 3 is a block diagram of an insulating bucket according to an embodiment of the present invention;
FIG. 4 is a schematic view of the first hydraulic lever and the second hydraulic lever in an embodiment of the present invention;
FIG. 5 is a contracted state diagram of the first hydraulic lever and the second hydraulic lever of the embodiment of the present invention;
FIG. 6 is a partial exploded view of a molding assembly according to an embodiment of the present invention;
fig. 7 is a diagram showing connection between the first hydraulic rod, the second hydraulic rod and the mandrel according to an embodiment of the present invention.
In the figure, 1, a bottom plate, 2, a storage box, 3, a forming assembly, 30, a forming barrel, 31, a mandrel, 32, a first hydraulic rod, 33, a second hydraulic rod, 34, a first arc-shaped core column sheet, 35, a second arc-shaped core column sheet, 36, a forming cavity, 37, a heat insulation barrel, 38, a water inlet pipe, 39, a water outlet pipe, 310, a heat insulation cavity, 4, a material pumping assembly, 41, a feed pipe, 42, a water pump, 43, a flow control valve, 5, a sealing ring, 6, a sealing cover, 7, a hydraulic pump, 8, an oil pipe, 9, a protective shell, 10, a feed inlet, 11, an upper end cover, 12 and an exhaust hole.
Detailed Description
The invention will now be described in further detail with reference to the accompanying drawings. The drawings are simplified schematic representations which merely illustrate the basic structure of the invention and therefore show only the structures which are relevant to the invention.
An embodiment of the preparation device of an artificial blood vessel with a microstructure on the inner surface of the artificial blood vessel comprises a bottom plate 1, a storage box 2 and a forming assembly 3, wherein the storage box 2 and the forming assembly 3 are arranged on the bottom plate 1, and the preparation device is shown in figures 1-7; the storage box 2 is communicated with the forming assembly 3 through the material drawing assembly 4; the material pumping assembly 4 conveys the liquid silica gel in the material storage box 2 into the forming cavity 36; the molding assembly 3 comprises a molding barrel 30, a mandrel 31 vertically arranged in the center of the molding barrel 30, a first hydraulic rod 32 and a second hydraulic rod 33 arranged on the mandrel 31, a first arc-shaped stem piece 34 connected with the telescopic end of the first hydraulic rod 32 and a second arc-shaped stem piece 35 connected with the telescopic end of the second hydraulic rod 33; the outer surfaces of the first arc-shaped stem piece 34 and the second arc-shaped stem piece 35 are respectively provided with a microstructure, when the telescopic rod of the first hydraulic rod 32 and the telescopic rod of the second hydraulic rod 33 are respectively ejected, the first arc-shaped stem piece 34 and the second arc-shaped stem piece 35 are combined to be cylindrical, the side edge of the first arc-shaped stem piece 34 is tightly attached to the side edge of the second arc-shaped stem piece 35, and a forming cavity 36 is formed among the outer wall of the first arc-shaped stem piece 34, the outer wall of the second arc-shaped stem piece 35 and the inner wall of the forming barrel 30; when the telescopic rod of the first hydraulic rod 32 and the telescopic rod of the second hydraulic rod 33 are sequentially contracted, the connection part of the first arc-shaped core column sheet 34 and the second arc-shaped core column sheet 35 is in a step shape; after the liquid silica gel is solidified into a silica gel tube, the microstructures on the outer surfaces of the first arc-shaped core column sheet 34 and the second arc-shaped core column sheet 35 are copied to the inner wall of the silica gel tube, and the first hydraulic rod 32 and the second hydraulic rod 33 respectively drive the first arc-shaped core column sheet 34 and the second arc-shaped core column sheet 35 to sequentially shrink inwards, so that the formed silica gel tube is separated from the first arc-shaped core column sheet 34 and the second arc-shaped core column sheet 35, demoulding can be completed, and the whole silica gel tube is taken out.
As shown in fig. 1 and 2, the material drawing assembly 4 comprises a material feeding pipe 41, one end of the material feeding pipe 41 is communicated with the material storage box 2, and the other end of the material feeding pipe 41 is communicated with the forming cavity 36; the feed pipe 41 is provided with a water pump 42 for extracting raw materials and a flow control valve 43 for controlling the conveying speed of the raw materials; a feed pipe 41 is arranged at the top end of the storage box 2 in a penetrating way, and the feed pipe 41 is arranged in a penetrating way through the forming barrel 30 at the same time; the water pump 42 is started to convey the liquid silica gel into the cavity of the forming cavity 36 through the feeding pipe 41, the liquid silica gel is located between the cavity of the forming cavity 36 and the first arc-shaped stem and the second arc-shaped stem pieces 35, and the conveying speed of the liquid silica gel can be set through the flow control valve 43.
As shown in fig. 2 to 7, in this embodiment, the mandrel 31 is provided as a hollow shaft, the center of the mandrel 31 is provided with a through hole, and the top end of the mandrel 31 is provided with the sealing ring 5 and the sealing cover 6. The forming assembly 3 further comprises a hydraulic pump 7 mounted on the bottom plate 1; the bottom end of the mandrel 31 is connected with the hydraulic pump 7 through the oil pipe 8, the hydraulic pump 7 is opened, and the first hydraulic rod 32 and the second hydraulic rod 33 are driven to eject or shrink by the oil absorption or the oil return of the hydraulic pump 7, so that the first arc-shaped stem piece 34 and the second arc-shaped stem piece 35 are driven to eject or shrink.
Referring to fig. 4, the oil inlet and the oil outlet of the first hydraulic rod 32 and the oil inlet and the oil outlet of the second hydraulic rod 33 are all communicated with the through hole in the center of the mandrel 31, the oil inlet and the oil outlet of the first hydraulic rod 32 are positioned above the oil inlet and the oil outlet of the second hydraulic rod 33, two first hydraulic rods 32 and two second hydraulic rods 33 are arranged, two first arc-shaped core column sheets 34 and two second arc-shaped core column sheets 35 are arranged, the two first hydraulic rods 32 are symmetrically arranged about the mandrel 31, the two second hydraulic rods 33 are symmetrically arranged about the mandrel 31, and the first hydraulic rods 32, the second hydraulic rods 33 and the mandrel 31 are vertically arranged in pairs; when the first hydraulic rod 32 and the second hydraulic rod 33 shrink inwards, the connection part of the first arc-shaped core column sheet 34 and the second arc-shaped core column sheet 35 is in a ladder shape; circular bosses are arranged on the inner sides of the first arc-shaped core column piece 34 and the second arc-shaped core column piece 35, the positions of the circular bosses on the first arc-shaped core column piece 34 are higher than those of the circular bosses on the second arc-shaped core column piece 35, and threaded holes are formed in the centers of the circular bosses; the fixed ends of the two first hydraulic rods 32 are arranged on the mandrel 31, and the telescopic ends are respectively and correspondingly connected with the circular bosses on the two first arc-shaped stem slices 34 in a threaded manner; the fixed ends of the two second hydraulic rods 33 are arranged on the mandrel 31, and the telescopic ends are respectively and correspondingly connected with the circular bosses on the two second arc-shaped stem slices 35 in a threaded manner.
In order to accelerate the solidification speed of silica gel, as shown in fig. 3, a heat preservation barrel 37 is further sleeved outside the molding barrel 30, a heat preservation cavity 310 is formed between the inner wall of the heat preservation barrel 37 and the outer wall of the molding barrel 30, a water inlet pipe 38 and a water outlet pipe 39 which are communicated with the heat preservation cavity 310 are arranged on the heat preservation barrel 37, the water inlet pipe 38 is positioned above the water outlet pipe 39, hot water is filled into the heat preservation cavity 310 through the water inlet pipe 38, liquid silica gel in the molding cavity 36 is heated, when the hot water in the heat preservation cavity 310 cools, the water outlet pipe 39 is opened to drain water, the water outlet pipe 39 is closed after the water drain is completed, hot water is filled into the heat preservation cavity 310 again through the water inlet pipe 38, the temperature of the liquid silica gel in the molding cavity 36 is kept at 65-70 ℃, the solidification speed of the liquid silica gel can be accelerated, and the preparation efficiency of artificial blood vessels is effectively improved.
Referring to fig. 2, a protective housing 9 is arranged outside the hydraulic pump 7, the forming barrel 30 and the heat-insulating barrel 37 are fixed on the top end of the protective housing 9 through screws, a mandrel 31 penetrates through the protective housing 9 and is fixedly connected with the protective housing 9, and the bottom of the mandrel 31 is connected with the protective housing 9 and is screwed and fixed through nuts.
As shown in fig. 2, a feed inlet 10 is arranged at the top end of the storage tank 2 for supplementing the liquid silica gel raw material.
Referring to fig. 1 and 2, in order to prevent sundries from entering the molding cavity 36 and enhance the heat preservation effect, the top end of the heat preservation barrel 37 is provided with an upper end cover 11, the center of the upper end cover 11 is provided with a hole for the mandrel 31 to penetrate, in order to monitor the temperature of liquid silica gel in the molding cavity 36 in real time, a temperature sensor is inserted in the molding cavity 36, the top end of the temperature sensor penetrates out of the upper end cover 11, an indication reading area of the temperature sensor is exposed outside and is convenient for reading the indication, when the temperature in the molding cavity 36 is lower than 65 degrees, water in the heat preservation cavity 310 is discharged through a water outlet pipe 39, after the water outlet pipe 39 is closed, hot water is injected into the heat preservation cavity 310 again from a water inlet pipe 38, so that the temperature in the molding cavity 36 can be always kept at 65-70 degrees, the curing speed of the liquid silica gel can be accelerated, and the efficiency can be effectively improved.
As shown in fig. 2, the upper end cover 11 is provided with an exhaust hole 12, and the exhaust hole 12 is located above the molding cavity 36 and is used for exhausting gas generated when the liquid silica gel is solidified.
When the micro-structure is used, the hydraulic pump 7 is started, oil enters the through hole in the center of the mandrel 31, the first hydraulic rod 32 and the second hydraulic rod 33 are in an ejection state, the first arc-shaped core column piece 34 and the second arc-shaped core column piece 35 are connected to be cylindrical, the hydraulic pump 7 is closed immediately, the first hydraulic rod 32 and the second hydraulic rod 33 are kept in the ejection state, the first arc-shaped core column piece 34 and the second arc-shaped core column piece 35 are connected to be cylindrical, liquid silica gel is poured into the storage box 2 through the feed inlet 10, the water pump 42 is started to press the liquid silica gel into the cavity 36, after the liquid silica gel reaches a certain height, the flow control valve 43 is opened to reduce the flow rate of the liquid silica gel, the water pump 42 is closed after the cavity 36 is filled with the liquid silica gel, hot water is added into the heat preservation cavity 310 through the water inlet pipe 38, the curing speed of the liquid silica gel can be accelerated, after the liquid silica gel is cured into the silica gel pipe, the micro-structures on the outer surfaces of the first arc-shaped core column piece 34 and the second arc-shaped core column piece 35 can be successfully copied to the inner wall of the silica gel pipe, the through hole in the center of the hydraulic pump 7 is opened again, the through hole in the center of the mandrel is changed into a lower state, the first core column state, the first arc-shaped core column is contracted, the whole surface is contracted, the whole curve-shaped silicon tube is contracted, and the inner curve is finally, the micro-structure is contracted, after the inner curve is completely is contracted, and the surface is completely contracted, and the micro-structure is finally is completely.
The preparation process of artificial blood vessel with micro structure in the inner surface includes the following steps:
s1, starting a hydraulic pump 7 to enable the telescopic rod of a first hydraulic rod 32 and the telescopic rod of a second hydraulic rod 33 to be always in an ejection state;
s2, turning on a water pump 42 to convey the liquid silica gel from the storage box 2 into the forming cavity 36, opening a flow control valve 43 to slow down the flow rate of the liquid silica gel when the liquid silica gel in the forming cavity 36 reaches a certain height, and immediately turning off the water pump 42 when the forming cavity 36 is filled with the liquid silica gel;
s3, closing the water outlet pipe 39, filling hot water into the heat preservation cavity 310 through the water inlet pipe 38, keeping the temperature of the liquid silica gel in the forming cavity 36 at 65-70 ℃, and accelerating the curing speed of the liquid silica gel;
s4, after the liquid silica gel is solidified into a silica gel tube, the hydraulic pump 7 is opened again, the through hole in the center of the mandrel 31 is gradually changed into a vacuum state from top to bottom, the first hydraulic rod 32 and the second hydraulic rod 33 drive the first arc-shaped stem piece 34 and the second arc-shaped stem piece 35 to shrink in sequence, demolding is completed, and the whole silica gel tube is taken out.
It should be understood that the above-described specific embodiments are only for explaining the present invention and are not intended to limit the present invention. Obvious variations or modifications which extend from the spirit of the present invention are within the scope of the present invention.
Claims (7)
1. The utility model provides a preparation facilities of vascular prosthesis that interior surface has microstructure which characterized in that: comprises a bottom plate (1), a storage box (2) and a forming assembly (3) which are arranged on the bottom plate (1); the storage box (2) is communicated with the forming assembly (3) through a material pumping assembly (4); the molding assembly (3) comprises a molding barrel (30), a mandrel (31) vertically arranged at the center of the molding barrel (30), a first hydraulic rod (32) and a second hydraulic rod (33) which are arranged on the mandrel (31), a first arc-shaped core column sheet (34) connected with the telescopic end of the first hydraulic rod (32) and a second arc-shaped core column sheet (35) connected with the telescopic end of the second hydraulic rod (33); when the telescopic rod of the first hydraulic rod (32) and the telescopic rod of the second hydraulic rod (33) are both ejected, the first arc-shaped core column sheet (34) and the second arc-shaped core column sheet (35) are combined to be cylindrical, and a forming cavity (36) is formed among the outer wall of the first arc-shaped core column sheet (34), the outer wall of the second arc-shaped core column sheet (35) and the inner wall of the forming barrel (30); when the telescopic rod of the first hydraulic rod (32) and the telescopic rod of the second hydraulic rod (33) are sequentially contracted, the joint of the first arc-shaped core column sheet (34) and the second arc-shaped core column sheet (35) is in a step shape; the oil inlet and the oil outlet of the first hydraulic rod (32) and the oil inlet and the oil outlet of the second hydraulic rod (33) are communicated with a through hole in the center of the mandrel (31), the oil inlet and the oil outlet of the first hydraulic rod (32) are positioned above the oil inlet and the oil outlet of the second hydraulic rod (33), and the first hydraulic rod (32) and the second hydraulic rod (33) are respectively provided with two parts; the first hydraulic rod (32), the second hydraulic rod (33) and the mandrel (31) are vertically arranged in pairs; the forming assembly (3) further comprises a hydraulic pump (7) mounted on the base plate (1); the bottom end of the mandrel (31) is connected with the hydraulic pump (7) through an oil pipe (8); the outer surfaces of the first arc-shaped stem pieces (34) and the second arc-shaped stem pieces (35) are provided with microstructures;
the center of dabber (31) is provided with the through-hole, the top of dabber (31) is provided with sealing washer (5) and sealed lid (6).
2. The device for preparing an artificial blood vessel having a microstructure on its inner surface according to claim 1, wherein: the material pumping assembly (4) comprises a feeding pipe (41); one end of the feed pipe (41) is communicated with the storage box (2), and the other end of the feed pipe is communicated with the forming cavity (36); the feeding pipe (41) is provided with a water pump (42) for extracting liquid silica gel and a flow control valve (43) for controlling the conveying speed of the liquid silica gel.
3. The device for preparing an artificial blood vessel having a microstructure on its inner surface according to claim 2, wherein: the forming barrel (30) is sleeved with a heat preservation barrel (37), a heat preservation cavity (310) is formed between the inner wall of the heat preservation barrel (37) and the outer wall of the forming barrel (30), and a water inlet pipe (38) and a water outlet pipe (39) which are communicated with the heat preservation cavity (310) are formed in the heat preservation barrel (37).
4. A device for preparing an artificial blood vessel having a microstructure on its inner surface as set forth in claim 3, wherein: the hydraulic pump (7) is provided with a protective shell (9) outside, the forming barrel (30) and the heat preservation barrel (37) are both fixed at the top end of the protective shell (9), and the mandrel (31) penetrates through the protective shell (9) and is fixedly connected with the protective shell (9).
5. The device for preparing an artificial blood vessel having a microstructure on its inner surface according to claim 4, wherein: the top of the storage box (2) is provided with a feed supplement opening (10).
6. The device for preparing an artificial blood vessel having a microstructure on its inner surface according to claim 5, wherein: the top of heat preservation bucket (37) is provided with upper end cover (11), be provided with exhaust hole (12) on upper end cover (11), exhaust hole (12) are located the top of shaping chamber (36).
7. A method of preparing an artificial blood vessel having a microstructure on its inner surface, using the apparatus of claim 3, comprising the steps of:
s1, starting a hydraulic pump (7) to enable a telescopic rod of a first hydraulic rod (32) and a telescopic rod of a second hydraulic rod (33) to extend out in sequence, wherein a first arc-shaped core column sheet (34) and a second arc-shaped core column sheet (35) are combined to form a cylinder;
s2, a water pump (42) is turned on, liquid silica gel is conveyed into a forming cavity (36) from a storage box (2), the liquid silica gel in the forming cavity (36) reaches a certain height, a flow control valve (43) is turned on, the flow rate of the liquid silica gel is slowed down, and when the forming cavity (36) is filled with the liquid silica gel, the water pump (42) is immediately turned off;
s3, closing a water outlet pipe (39), filling hot water into the heat preservation cavity (310) through a water inlet pipe (38), keeping the temperature of liquid silica gel in the forming cavity (36) at 65-70 ℃, and accelerating the curing speed of the liquid silica gel;
s4, after the liquid silica gel is solidified into a silica gel tube, the hydraulic pump (7) is opened again, the through hole in the center of the mandrel (31) is gradually changed into a vacuum state from top to bottom, so that the first hydraulic rod (32) and the second hydraulic rod (33) sequentially drive the first arc-shaped core column sheet (34) and the second arc-shaped core column sheet (35) to shrink, demolding is completed, and the whole silica gel tube is taken out.
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