CN115038381A - 用于检测多种分析物的传感器阵列系统和方法 - Google Patents

用于检测多种分析物的传感器阵列系统和方法 Download PDF

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Publication number
CN115038381A
CN115038381A CN202080095498.8A CN202080095498A CN115038381A CN 115038381 A CN115038381 A CN 115038381A CN 202080095498 A CN202080095498 A CN 202080095498A CN 115038381 A CN115038381 A CN 115038381A
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CN
China
Prior art keywords
analyte
sensor
active region
working electrode
responsive active
Prior art date
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Pending
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CN202080095498.8A
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English (en)
Chinese (zh)
Inventor
王宜
H·赵
B·J·费尔德曼
陈冠州
L·N·德兰
S·奥贾
J·D·麦坎莱斯
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Abbott Diabetes Care Co
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Abbott Diabetes Care Co
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Publication of CN115038381A publication Critical patent/CN115038381A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1468—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
    • A61B5/1486—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
    • A61B5/14865—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/12—Manufacturing methods specially adapted for producing sensors for in-vivo measurements
    • A61B2562/125—Manufacturing methods specially adapted for producing sensors for in-vivo measurements characterised by the manufacture of electrodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/16—Details of sensor housings or probes; Details of structural supports for sensors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/683—Means for maintaining contact with the body
    • A61B5/6832—Means for maintaining contact with the body using adhesives
    • A61B5/6833—Adhesive patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
    • A61B5/6848—Needles

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Medical Informatics (AREA)
  • Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Optics & Photonics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CN202080095498.8A 2020-01-03 2020-12-30 用于检测多种分析物的传感器阵列系统和方法 Pending CN115038381A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202062956943P 2020-01-03 2020-01-03
US62/956,943 2020-01-03
PCT/US2020/067541 WO2021138473A1 (en) 2020-01-03 2020-12-30 Sensor array systems and methods for detecting multiple analytes

Publications (1)

Publication Number Publication Date
CN115038381A true CN115038381A (zh) 2022-09-09

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CN202080095498.8A Pending CN115038381A (zh) 2020-01-03 2020-12-30 用于检测多种分析物的传感器阵列系统和方法

Country Status (8)

Country Link
US (2) US12290359B2 (https=)
EP (1) EP4084689A4 (https=)
JP (3) JP7590439B2 (https=)
CN (1) CN115038381A (https=)
AU (2) AU2020419193B2 (https=)
BR (1) BR112022013271A2 (https=)
CA (1) CA3162903A1 (https=)
WO (1) WO2021138473A1 (https=)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024199303A1 (zh) * 2023-03-30 2024-10-03 华为技术有限公司 生物传感器的制备方法以及生物传感器及其相关产品
WO2025061126A1 (zh) * 2023-09-22 2025-03-27 上海移宇科技有限公司 集成温度检测的长寿命分析物传感器
WO2025214327A1 (zh) * 2024-04-12 2025-10-16 南京晶捷生物科技有限公司 一种干膜自校准传感装置及其检测分析物浓度的方法

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK3423591T3 (da) 2016-03-04 2024-01-29 Abbott Diabetes Care Inc NAD(P)-afhængige sensitive enzymer, elektroder og sensorer og fremgangsmåder til fremstilling og anvendelse deraf
EP4574038A3 (en) 2019-01-28 2025-08-27 Abbott Diabetes Care, Inc. Analyte sensors and sensing methods featuring dual detection of glucose and ketones
CA3126240A1 (en) 2019-01-28 2020-08-06 Abbott Diabetes Cares Inc. Analyte sensors employing multiple enzymes and methods associated therewith
CN115038381A (zh) 2020-01-03 2022-09-09 美国雅培糖尿病护理公司 用于检测多种分析物的传感器阵列系统和方法
WO2022170283A1 (en) * 2021-02-08 2022-08-11 Informed Data Systems Inc. Biosensor excitation methods, and associated systems, devices, and methods
US12226239B2 (en) 2021-09-15 2025-02-18 Lingo Sensing Technology Unlimited Company Systems, devices, and methods for applications for communication with ketone sensors
EP4151151A1 (en) * 2021-09-21 2023-03-22 F. Hoffmann-La Roche AG Sensor with varying stiffness
US12442786B2 (en) 2021-10-14 2025-10-14 Medtronic Minimed, Inc. Sensors for 3-hydroxybutyrate detection
EP4493059A1 (en) * 2022-03-18 2025-01-22 DexCom, Inc. Continuous multi-analyte sensor systems
AU2023257941A1 (en) * 2022-04-19 2024-10-24 University Of Cincinnati Multimode sensor integration onto needle-based sensing systems
WO2024192181A1 (en) * 2023-03-16 2024-09-19 Dexcom, Inc. Continuous multi- analyte sensor systems
CN116735885B (zh) * 2023-05-25 2025-02-11 深圳硅基传感科技有限公司 多分析物监测传感器
WO2025040616A1 (en) * 2023-08-22 2025-02-27 Roche Diagnostics Gmbh Sensor for detecting a plurality of analytes
US20250169728A1 (en) * 2023-09-01 2025-05-29 Abbott Diabetes Care Inc. Sensor for detecting glucose and lactate and methods for determining aerobic and anaerobic thresholds
CN121843651A (zh) 2023-09-22 2026-04-10 雅培糖尿病护理公司 葡萄糖-酮传感器的决策支持
WO2025071951A1 (en) * 2023-09-29 2025-04-03 Abbott Diabetes Care, Inc. Systems, devices, and methods for analyte monitoring
US20250299818A1 (en) 2024-03-25 2025-09-25 Abbott Diabetes Care Inc. Deployment and use of a continuous analyte monitoring system for improved home monitoring and readmission optimization
US20260007334A1 (en) * 2024-07-03 2026-01-08 Laxmi Therapeutic Devices, Inc. Small-scale analyte sensors

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050148832A1 (en) * 2003-12-26 2005-07-07 Medtronic Minimed, Inc. Implantable apparatus for sensing multiple parameters
WO2008041984A1 (en) * 2006-10-04 2008-04-10 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
WO2018106129A1 (en) * 2016-12-09 2018-06-14 Digital Sensing Limited Electrochemical sensors and methods of use thereof

Family Cites Families (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2067764B (en) 1980-01-09 1984-01-25 Nat Res Dev Transcutaneous gas sensor
US4680268A (en) 1985-09-18 1987-07-14 Children's Hospital Medical Center Implantable gas-containing biosensor and method for measuring an analyte such as glucose
US5322063A (en) 1991-10-04 1994-06-21 Eli Lilly And Company Hydrophilic polyurethane membranes for electrochemical glucose sensors
US5792621A (en) 1995-06-28 1998-08-11 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Fiber-optic chemiluminescent biosensors for monitoring aqueous alcohols and other water quality parameters
US5696314A (en) 1996-07-12 1997-12-09 Chiron Diagnostics Corporation Multilayer enzyme electrode membranes and methods of making same
US6736957B1 (en) 1997-10-16 2004-05-18 Abbott Laboratories Biosensor electrode mediators for regeneration of cofactors and process for using
US6030827A (en) 1998-01-23 2000-02-29 I-Stat Corporation Microfabricated aperture-based sensor
US6134461A (en) 1998-03-04 2000-10-17 E. Heller & Company Electrochemical analyte
US6241863B1 (en) 1998-04-27 2001-06-05 Harold G. Monbouquette Amperometric biosensors based on redox enzymes
US8688188B2 (en) 1998-04-30 2014-04-01 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8268143B2 (en) 1999-11-15 2012-09-18 Abbott Diabetes Care Inc. Oxygen-effect free analyte sensor
US8444834B2 (en) 1999-11-15 2013-05-21 Abbott Diabetes Care Inc. Redox polymers for use in analyte monitoring
DE60035123T2 (de) 1999-11-15 2008-01-31 Therasense, Inc., Alameda Übergangsmetallkomplexe, die über ein bewegliches zwischenglied an ein polymer gebunden sind
US6932894B2 (en) 2001-05-15 2005-08-23 Therasense, Inc. Biosensor membranes composed of polymers containing heterocyclic nitrogens
US6915147B2 (en) 2001-09-07 2005-07-05 Medtronic Minimed, Inc. Sensing apparatus and process
GB0130684D0 (en) 2001-12-21 2002-02-06 Oxford Biosensors Ltd Micro-band electrode
US6946299B2 (en) 2002-04-25 2005-09-20 Home Diagnostics, Inc. Systems and methods for blood glucose sensing
US20040061232A1 (en) 2002-09-27 2004-04-01 Medtronic Minimed, Inc. Multilayer substrate
US7501053B2 (en) 2002-10-23 2009-03-10 Abbott Laboratories Biosensor having improved hematocrit and oxygen biases
US9763609B2 (en) 2003-07-25 2017-09-19 Dexcom, Inc. Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise
WO2005040404A1 (en) 2003-10-29 2005-05-06 Agency For Science, Technology And Research Biosensor
US7577470B2 (en) 2003-11-13 2009-08-18 Medtronic Minimed, Inc. Long term analyte sensor array
ATE480761T1 (de) 2003-12-05 2010-09-15 Dexcom Inc Kalibrationsmethoden für einen kontinuierlich arbeitenden analytsensor
US8165651B2 (en) 2004-02-09 2012-04-24 Abbott Diabetes Care Inc. Analyte sensor, and associated system and method employing a catalytic agent
US20070270672A1 (en) 2004-08-31 2007-11-22 Hayter Paul G Wearable Sensor Device and System
US8211038B2 (en) 2004-09-17 2012-07-03 Abbott Diabetes Care Inc. Multiple-biosensor article
US8060174B2 (en) 2005-04-15 2011-11-15 Dexcom, Inc. Analyte sensing biointerface
US20070095661A1 (en) 2005-10-31 2007-05-03 Yi Wang Method of making, and, analyte sensor
PL2205964T3 (pl) 2007-09-24 2015-12-31 Bayer Healthcare Llc Czujniki testowe, sposoby oraz systemy o wielu rejonach i potencjałach
WO2009100082A1 (en) * 2008-02-04 2009-08-13 Bayer Healthcare Llc Semiconductor based analyte sensors and methods
US20100213057A1 (en) 2009-02-26 2010-08-26 Benjamin Feldman Self-Powered Analyte Sensor
FI3912551T3 (fi) * 2009-02-26 2023-10-31 Abbott Diabetes Care Inc Parannettuja analyyttiantureita ja menetelmiä niiden valmistamiseksi ja käyttämiseksi
EP2473963A4 (en) 2009-08-31 2014-01-08 Abbott Diabetes Care Inc MEDICAL DEVICES AND METHOD
US20120181189A1 (en) 2009-09-24 2012-07-19 Fresenius Medical Care Holdings, Inc. Amperometric Creatinine Biosensor With Immobilized Enzyme-Polymer Composition And Systems Using Same, And Methods
US8545693B2 (en) * 2009-09-29 2013-10-01 Lifescan Scotland Limited Analyte measurment method and system
US9402574B2 (en) 2010-06-25 2016-08-02 The University Of Connecticut Sensors for analyte detection and methods of manufacture thereof
DK2598021T3 (da) 2010-07-28 2015-09-28 Abbott Diabetes Care Inc Analytsensorer med temperaturuafhængige membraner
EP2608715B1 (en) 2010-08-24 2016-06-22 Microchips, Inc. Implantable biosensor device and methods of use thereof
US20140054171A1 (en) * 2012-02-21 2014-02-27 Abbott Diabetes Care Inc. Analyte Sensor Utilizing Oxygen as Oxidant
US9535027B2 (en) 2012-07-25 2017-01-03 Abbott Diabetes Care Inc. Analyte sensors and methods of using same
US9743871B2 (en) * 2012-09-24 2017-08-29 Dexcom, Inc. Multiple electrode system for a continuous analyte sensor, and related methods
US8921061B2 (en) 2012-11-02 2014-12-30 Roche Diagnostics Operations, Inc. Reagent materials and associated test elements
US9344777B2 (en) 2012-12-20 2016-05-17 Abbott Diabetes Care Inc. Wireless communication authentication for medical monitoring device
AU2016280696B2 (en) 2015-06-15 2021-11-18 Abbott Diabetes Care Inc. Stabilized lactate responsive enzymes, electrodes and sensors, and methods for making and using the same
US10324058B2 (en) 2016-04-28 2019-06-18 Medtronic Minimed, Inc. In-situ chemistry stack for continuous glucose sensors
EP4538692A3 (en) 2017-06-30 2025-06-18 Abbott Diabetes Care Method and apparatus for analyte detection using an electrochemical biosensor
EP3703564A1 (en) 2017-10-30 2020-09-09 Abbott Diabetes Care Inc. Transcutaneous sensor with dual electrodes and methods of detecting and compensating for withdrawal of a transcutaneous sensor from a patient
US12076145B2 (en) 2018-04-19 2024-09-03 Abbott Diabetes Care Inc. Lactate sensors and associated methods
EP4574038A3 (en) 2019-01-28 2025-08-27 Abbott Diabetes Care, Inc. Analyte sensors and sensing methods featuring dual detection of glucose and ketones
EP4552566A1 (en) 2019-01-28 2025-05-14 Abbott Diabetes Care, Inc. Analyte sensors and sensing methods for detecting creatinine
CA3126240A1 (en) 2019-01-28 2020-08-06 Abbott Diabetes Cares Inc. Analyte sensors employing multiple enzymes and methods associated therewith
CN113453620B (zh) 2019-01-28 2024-03-05 美国雅培糖尿病护理公司 用于双重检测葡萄糖和乙醇的分析物传感器和感测方法
CN115038381A (zh) 2020-01-03 2022-09-09 美国雅培糖尿病护理公司 用于检测多种分析物的传感器阵列系统和方法

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050148832A1 (en) * 2003-12-26 2005-07-07 Medtronic Minimed, Inc. Implantable apparatus for sensing multiple parameters
WO2008041984A1 (en) * 2006-10-04 2008-04-10 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
WO2018106129A1 (en) * 2016-12-09 2018-06-14 Digital Sensing Limited Electrochemical sensors and methods of use thereof

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024199303A1 (zh) * 2023-03-30 2024-10-03 华为技术有限公司 生物传感器的制备方法以及生物传感器及其相关产品
WO2025061126A1 (zh) * 2023-09-22 2025-03-27 上海移宇科技有限公司 集成温度检测的长寿命分析物传感器
WO2025214327A1 (zh) * 2024-04-12 2025-10-16 南京晶捷生物科技有限公司 一种干膜自校准传感装置及其检测分析物浓度的方法

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Publication number Publication date
JP2026063183A (ja) 2026-04-10
AU2020419193B2 (en) 2024-07-04
BR112022013271A2 (pt) 2022-09-06
US20250295337A1 (en) 2025-09-25
EP4084689A1 (en) 2022-11-09
US12290359B2 (en) 2025-05-06
WO2021138473A1 (en) 2021-07-08
AU2024204183A1 (en) 2024-07-11
AU2020419193A1 (en) 2022-07-07
US20210219885A1 (en) 2021-07-22
EP4084689A4 (en) 2024-01-17
JP7807512B2 (ja) 2026-01-27
JP7590439B2 (ja) 2024-11-26
JP2023509450A (ja) 2023-03-08
CA3162903A1 (en) 2021-07-08
JP2025015649A (ja) 2025-01-30

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