CN115024816A - Cold circulation microwave tumor ablation system - Google Patents
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Abstract
The invention is suitable for the technical field of microwave ablation, provides a cold circulation microwave tumor ablation system, and solves the problems that the existing microwave ablation needle system cannot simulate the tumor form in a tumor target area, increases the difficulty of microwave ablation, and is not beneficial to treatment and rehabilitation of patients; the method comprises the following steps: the tumor state simulation module is used for responding to at least one group of tumor ablation requests and is also used for forming a tumor state display area at a doctor end; the tumor target area ablation module is used for executing tumor ablation operation of the corresponding tumor target area, and executing the tumor ablation operation of the corresponding tumor target area based on operation of a microwave tumor ablation instrument; a tumor ablation cooling module; the tumor state simulation module is arranged in the embodiment of the invention, and the tumor state display area can be formed at the end of a doctor by the tumor state simulation module, so that the doctor and a patient can conveniently observe the real-time state of the tumor in the patient, the tumor can be conveniently ablated, and the rehabilitation of the patient is facilitated.
Description
Technical Field
The invention belongs to the technical field of microwave ablation, and particularly relates to a cold circulation microwave tumor ablation system.
Background
The microwave technology is a new technology developed in the twentieth century, and is widely applied to various fields such as communication, aerospace, medical treatment and the like at present. Due to the heat effect of the microwave and the non-heat effect of biochemistry, microwave physiotherapy, microwave surgery and microwave acupuncture and moxibustion achieve very obvious effects in the medical field.
The tumor microwave ablation technology leads the protein of the tumor cells to be denatured and solidified through high temperature, and has the characteristics of simplicity, convenience and safety due to the continuous perfection of various technologies, and compared with radio frequency, the tumor microwave ablation technology has high heat efficiency and short operation time.
Chinese patent CN202751443U discloses a microwave ablation needle system, including microwave ablation needle body and microwave ablation needle controller, the microwave ablation needle body includes data storage module, and data storage module includes: the storage area is used for storing the identification signal of the microwave ablation needle body; the microwave ablation needle controller comprises: the signal recording module is used for reading the microwave ablation needle body identification signal from the storage area and recording the microwave ablation needle body identification signal when the microwave ablation needle body is connected with the microwave ablation needle controller, and the signal recording module is connected with the storage area; the alarm module is used for sending an alarm signal when the identification signal of the microwave ablation needle body is an unacceptable identification signal and is connected with the signal recording module; the unacceptable identification signals comprise recorded microwave ablation needle body identification signals, but the existing microwave ablation needle system cannot simulate the form of a tumor in a tumor target area, so that the difficulty of microwave ablation is increased, and the treatment and the rehabilitation of a patient are not facilitated, so that a cold circulation microwave tumor ablation system is provided.
Disclosure of Invention
The invention provides a cold circulation microwave tumor ablation system, and aims to solve the problems that the existing microwave ablation needle system cannot simulate the tumor form in a tumor target area, the microwave ablation difficulty is increased, and the treatment and the rehabilitation of a patient are not facilitated.
The invention is thus achieved, a cold-cycle microwave tumor ablation system comprising:
the tumor state simulation module is used for responding to at least one group of tumor ablation requests, the tumor ablation requests comprise tumor treatment information and predicted ablation results, and the tumor state simulation module is also used for forming a tumor state display area at a doctor end;
the tumor target area ablation module is used for executing tumor ablation operation of the corresponding tumor target area, and executing the tumor ablation operation of the corresponding tumor target area based on operation of a microwave tumor ablation instrument;
and the tumor ablation cooling module acquires the operation state of the microwave tumor ablation instrument, executes the cooling work of the microwave tumor ablation instrument according to the operation state of the microwave tumor ablation instrument and pushes the cooling work to the tumor state simulation module.
Preferably, the tumor status simulation module comprises:
the patient pathological state acquisition unit is used for acquiring preoperative pathological states of the patient, wherein the preoperative pathological states of the patient comprise preoperative tumor pathological images of the patient and clinical diagnosis results of the patient;
the tumor target area matching unit is used for receiving a matching request sent by the multi-channel matching equipment according to a preset rule, wherein the matching request carries a current tumor position, current patient body function parameters and a patient tumor identification code;
the tumor state model establishing unit is used for screening the optimal tumor state model from the corresponding tumor state model storage system based on the matching request and acquiring the identification code of the optimal tumor state model;
and the tumor state imaging unit acquires a tumor state model establishing instruction, wherein the tumor state model establishing instruction comprises an identification code containing the tumor state model.
Preferably, the tumor status simulation module further comprises:
the patient tumor three-dimensional space positioning unit is used for positioning a target area of a tumor to be ablated by a patient, is connected with the microwave tumor ablation instrument, acquires an ultrasonic image of the target area of the tumor through the microwave tumor ablation instrument, and determines three-dimensional position and angle information of the target area of the tumor based on the acquired ultrasonic image.
Preferably, the tumor state imaging unit includes:
the positioning data acquisition unit is used for acquiring the three-dimensional position and angle information of the tumor target area sent by the patient tumor three-dimensional space positioning unit;
the positioning data input unit is used for inputting the three-dimensional position and angle information of a tumor target area, executing a tumor state model and establishing a tumor three-dimensional image;
the three-dimensional image denoising unit is used for acquiring tumor three-dimensional image data and determining a characteristic response result of a pixel point in an image to be corrected in a response direction according to the tumor three-dimensional image data, wherein the characteristic response result comprises a scale parameter of a standard tumor three-dimensional image;
and the three-dimensional image reconstruction unit acquires the tumor three-dimensional image subjected to noise reduction, and determines the optimal characteristic response result through a non-classical receptive field edge detection algorithm to obtain a reconstructed tumor three-dimensional image.
Preferably, the tumor target ablation module comprises:
the tumor state acquisition unit is used for acquiring a real-time state of a tumor to be ablated, wherein the real-time state of the tumor comprises a tumor ultrasonic image acquired by the tumor detector and a simulated tumor three-dimensional image;
the ablation scheme traversal unit is used for traversing the tumor pathology database step by step to generate a tumor target area ablation scheme library corresponding to the characteristic position of the patient;
and the ablation result derivation unit is used for loading the ablation scheme library of the tumor target area, screening the recommended ablation scheme of the corresponding patient and pushing the recommended ablation scheme of the corresponding patient.
Preferably, the method for establishing the tumor pathology database specifically comprises:
collecting existing pathological data of tumor patients, wherein the pathological data of the tumor patients record the diagnosis time of the patients and the diagnosis confirmed data of the patients, and the diagnosis confirmed data of the patients comprise the age, the sex, the blood test, the urine test, the surgical plan, the hospitalization time and the rehabilitation follow-up medical characteristic data of the patients;
acquiring collected pathological data of a patient, and carrying out classified induction on the pathological data of the patient to obtain a treatment data set of the patient;
and (3) adopting a Cox regression analysis method and a machine learning algorithm to construct a post-operation effect prediction model of each group of patient treatment data sets, training the post-operation effect prediction model, and screening out a Cox regression analysis method model and a machine learning algorithm model which contain effective post-operation effect models.
Preferably, the tumor ablation cooling module comprises:
the real-time ablation data acquisition unit is used for acquiring real-time ablation data of the microwave tumor ablation instrument, wherein the real-time ablation data of the microwave tumor ablation instrument comprises the temperature of an ablation needle and the real-time temperature of a tumor target area;
and the simulated thermal field model acquisition unit takes real-time ablation data of the microwave tumor ablation instrument as input to generate a simulated thermal field model architecture tree, and the simulated thermal field model architecture tree contains the real-time temperature of a key area of the tumor target area.
Preferably, the tumor ablation cooling module further comprises:
the ablation cooling request acquisition unit is used for acquiring an access request of a doctor end, wherein the access request comprises a unique doctor end identifier and a doctor end access password;
and the tumor target area cooling execution unit is used for verifying the unique identifier of the doctor end and the access password of the doctor end, loading a tumor target area cooling scheme, and modifying the temperature of the ablation needle and the temperature of the tumor target area.
Preferably, the tumor target cooling execution unit comprises:
the historical cooling data storage module is used for storing historical cooling data and generating a historical cooling data set;
the cooling scheme importing module is used for acquiring a historical cooling scheme corresponding to historical cooling data;
and the cooling scheme execution module trains according to the historical cooling scheme, edits the historical cooling scheme or adds a cooling scheme according to the target tumor type.
Preferably, the ablation effect evaluation module is further included, and comprises:
the tumor target area ablation calculation unit is used for calculating the ablation efficiency of the tumor target area based on the tumor three-dimensional image and an ablation needle connected with the microwave tumor ablation instrument;
the ablation effect display unit generates a virtual real-time ablation three-dimensional model at a doctor end and renders the ablation three-dimensional model to a virtual tumor three-dimensional image;
and the ablation effect feedback unit is used for outputting ablation information and an ablation effect in a doctor end display area based on the rendered virtual tumor three-dimensional image.
Compared with the prior art, the embodiment of the application mainly has the following beneficial effects:
the tumor state simulation module is arranged in the embodiment of the invention, and the tumor state display area can be formed at the end of a doctor by the tumor state simulation module, so that the doctor and a patient can conveniently observe the real-time state of the tumor in the patient, the tumor can be conveniently ablated, and the rehabilitation of the patient is facilitated.
Drawings
Fig. 1 is a schematic structural diagram of a cold-cycle microwave tumor ablation system provided by the present invention.
Fig. 2 is a schematic structural diagram of a tumor status simulation module provided in the present invention.
Fig. 3 is a schematic structural diagram of a tumor state imaging unit provided by the present invention.
Fig. 4 is a schematic structural diagram of a tumor target region ablation module provided by the invention.
Fig. 5 is a schematic view of an implementation process of establishing a tumor pathology database according to the present invention.
Fig. 6 is a schematic structural diagram of a tumor ablation cooling module provided by the present invention.
Fig. 7 is a schematic structural diagram of a tumor target region cooling execution unit provided by the invention.
Fig. 8 is a schematic structural diagram of an ablation effect evaluation module provided by the present invention.
Fig. 9 is a schematic flow chart of an implementation of the cold-circulation microwave tumor ablation method provided by the invention.
Fig. 10 is a schematic flow chart of an implementation of the present invention for responding to at least one group of tumor ablation requests.
In the figure: 100-tumor state simulation module, 110-patient pathological state acquisition unit, 120-tumor target area matching unit, 130-tumor state model establishment unit, 140-tumor state imaging unit, 141-positioning data acquisition unit, 142-positioning data input unit, 143-three-dimensional image denoising unit, 144-three-dimensional image reconstruction unit, 150-patient tumor three-dimensional space positioning unit, 200-tumor target area ablation module, 210-tumor state acquisition unit, 220-ablation scheme traversal unit, 230-ablation result derivation unit, 300-tumor ablation cooling module, 310-real-time ablation data acquisition unit, 320-simulation thermal field model acquisition unit, 330-ablation cooling request acquisition unit, 340-tumor target area cooling execution unit, 120-tumor target area matching unit, 130-tumor state model establishment unit, 140-tumor state imaging unit, 141-positioning data acquisition unit, 142-positioning data input unit, 143-three-dimensional image denoising unit, 144-three-dimensional image reconstruction unit, 150-patient tumor three-dimensional space positioning unit, 200-tumor target area ablation module, 210-ablation cooling request acquisition unit, 340-tumor target area cooling execution unit, 340-simulation thermal field model acquisition unit, and, 341-historical cooling data storage module, 342-cooling scheme introduction module, 343-cooling scheme execution module, 400-ablation effect evaluation module, 410-tumor target area ablation calculation unit, 420-ablation effect display unit and 430-ablation effect feedback unit.
Detailed Description
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this application belongs; the terminology used in the description of the application herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the application; the terms "including" and "having," and any variations thereof, in the description and claims of this application and the description of the above figures are intended to cover non-exclusive inclusions. The terms "first," "second," and the like in the description and claims of this application or in the above-described drawings are used for distinguishing between different objects and not for describing a particular order.
Reference herein to "an embodiment" means that a particular feature, structure, or characteristic described in connection with the embodiment can be included in at least one embodiment of the application. The appearances of the phrase in various places in the specification are not necessarily all referring to the same embodiment, nor are separate or alternative embodiments mutually exclusive of other embodiments. It is explicitly and implicitly understood by one skilled in the art that the embodiments described herein can be combined with other embodiments.
The existing microwave ablation needle system can not simulate the form of a tumor in a tumor target area, increases the difficulty of microwave ablation, and is not beneficial to treatment and rehabilitation of a patient, so that a cold-cycle microwave tumor ablation system is provided, the cold-cycle microwave tumor ablation system comprises a module 100 for responding at least one group of tumor ablation requests, the tumor ablation requests comprise tumor treatment information and predicted ablation results, the tumor state simulation module 100 is also used for forming a tumor state display area at a doctor end, is used for executing the tumor ablation operation of the corresponding tumor target area, executing the tumor target area ablation operation 200 of the corresponding tumor target area based on the microwave tumor ablation instrument operation, and is used for acquiring the operation state of the microwave tumor ablation instrument and executing the cooling operation of the microwave tumor ablation instrument according to the operation state of the microwave tumor ablation instrument, the tumor ablation cooling module 300 is pushed to the tumor state simulation module 100, the tumor state simulation module 100 is arranged in the embodiment of the invention, and the tumor state simulation module 100 can form a tumor state display area at a doctor end, so that the doctor and the patient can observe the real-time state of the tumor in the patient conveniently, the tumor ablation is facilitated, and the rehabilitation of the patient is facilitated.
An embodiment of the present invention provides a cold-cycle microwave tumor ablation system, as shown in fig. 1, the cold-cycle microwave tumor ablation system includes:
the tumor status simulation module 100 is configured to respond to at least one group of tumor ablation requests, where the tumor ablation requests include tumor treatment information and expected ablation results, and the tumor status simulation module 100 is further configured to form a tumor status display area at a doctor end.
In this embodiment, the doctor end is the smart phone, the tablet computer, the computer and the terminal of independently that can input the instruction specifically, and tumour state simulation module 100 can feed back the tumour that simulates to the doctor end in real time to make things convenient for the doctor to judge the tumour state, do benefit to going on of patient's operation.
In this embodiment, the tumor treatment information includes, but is not limited to, historical tumor ultrasound images and patient diagnosis information, where the historical tumor ultrasound images are processed based on a convolutional neural training network, and the convolutional neural training network can identify an image and detect and classify substances in a tumor target region.
In this embodiment, the convolutional neural training network is divided into a first training network, a second training network, and a third training network, and the first training network, the second training network, and the third training network are subjected to convergence training by acquiring a plurality of groups of standard images of patients, and standard parameters of the first training network, the second training network, and the third training network are respectively obtained by gaussian initialization, so that the convolutional neural training network is finally constructed.
The tumor target area ablation module 200 is used for executing the tumor ablation operation of the corresponding tumor target area, and the execution of the tumor ablation operation of the corresponding tumor target area is based on the operation of a microwave tumor ablation instrument.
In this embodiment, the module 200 is ablated at the target area of tumour is carried on in current tumour ablation instrument, and the module 200 is ablated at the target area of tumour acquires the accurate position in tumour target area that tumour state simulation module 100 obtained to carry out and ablate the operation, guaranteed the accurate nature that tumour target area was ablated.
For example, during operation, the tumor state simulation module 100 performs physical examination on a patient to obtain a two-dimensional ultrasound image of a tumor in the patient, the tumor state simulation module 100 performs preprocessing and processing on the two-dimensional ultrasound image to finally three-dimensionally convert the ultrasound image and present the ultrasound image at the doctor end, and then the tumor target region ablation module 200 performs ablation operation, thereby avoiding the phenomenon of false ablation in the operation process.
The tumor ablation cooling module 300 obtains the operation state of the microwave tumor ablation instrument, executes the cooling work of the microwave tumor ablation instrument according to the operation state of the microwave tumor ablation instrument, and pushes the cooling work to the tumor state simulation module 100.
In this embodiment, the tumor ablation request includes tumor treatment information and a predicted ablation result, the tumor state simulation module 100 is further configured to form a tumor state simulation module 100 in which a tumor state display area is formed at a doctor end, to execute a tumor ablation operation corresponding to a tumor target area, to execute a tumor target area ablation module 200 in which the tumor ablation operation corresponding to the tumor target area is based on an operation of a microwave tumor ablation instrument, and to acquire an operation state of the microwave tumor ablation instrument, to execute a cooling operation of the microwave tumor ablation instrument according to the operation state of the microwave tumor ablation instrument, and to push the cooling operation to the tumor ablation cooling module 300 of the tumor state simulation module 100, the tumor state simulation module 100 is provided in the embodiment of the present invention, and the tumor state simulation module 100 can form the tumor state display area at the doctor end, so as to facilitate the doctor and the patient to observe a real-time state of the tumor in the patient, the tumor ablation is convenient, and the rehabilitation of the patient is facilitated.
In a further preferred embodiment of the present invention, as shown in fig. 2, the tumor status simulation module 100 comprises:
a patient pathological state acquiring unit 110, configured to acquire a preoperative pathological state of a patient, where the preoperative pathological state of the patient includes a preoperative tumor pathological image of the patient and a clinical diagnosis result of the patient;
a tumor target matching unit 120, configured to receive a matching request sent by a multi-channel matching device according to a predetermined rule, where the matching request carries a current tumor position, a current patient body function parameter, and a patient tumor identification code;
a tumor status model establishing unit 130, configured to screen an optimal tumor status model from the corresponding tumor status model storage system based on the matching request, and obtain an identification code of the optimal tumor status model;
the tumor-state imaging unit 140 acquires a tumor-state model establishment instruction, wherein the tumor-state model establishment instruction includes an identification code containing a tumor-state model.
In this embodiment, in operation, the patient pathological state obtaining unit 110 obtains the pre-operation pathological state of the patient, the tumor target matching unit 120 receives a matching request sent by the multi-channel matching device according to a predetermined rule, the tumor state model establishing unit 130 screens an optimal tumor state model from the corresponding tumor state model storage system based on the matching request, obtains an identification code of the optimal tumor state model, and finally the tumor state imaging unit 140 obtains a tumor state model establishing instruction, where the tumor state model establishing instruction includes the identification code of the tumor state model.
In this embodiment, the clinical diagnosis result of the patient includes a treatment agreement and a treatment promissory book signed before and after the operation, and also includes the treatment condition of the patient, the instrument used for the treatment, the instrument state and the treatment effect evaluation, and the clinical diagnosis result of the patient is stored in the doctor end, thereby facilitating the later inquiry.
In this embodiment, the tumor status simulation module 100 further includes:
the patient tumor three-dimensional space positioning unit 150 is used for positioning a target area of a tumor to be ablated by a patient, is connected with the microwave tumor ablation instrument, acquires an ultrasonic image of the target area of the tumor through the microwave tumor ablation instrument, and determines three-dimensional position and angle information of the target area of the tumor based on the acquired ultrasonic image.
In this embodiment, the three-dimensional position and angle information of the tumor target area are determined by the ultrasound image, the ultrasound image needs to be cut and grouped, then an interference threshold is set, a cut image set within the interference threshold is selected, and the ultrasound image from which the interference factors are screened out is obtained, so that the three-dimensional position and angle information of the tumor target area can be conveniently obtained.
In a further preferred embodiment of the present invention, as shown in fig. 3, the tumor state imaging unit 140 comprises:
a positioning data obtaining unit 141, configured to obtain three-dimensional position and angle information of the tumor target area sent by the patient tumor three-dimensional space positioning unit 150;
a positioning data input unit 142, which inputs the three-dimensional position and angle information of the tumor target area, executes a tumor state model, and establishes a tumor three-dimensional image;
the three-dimensional image denoising unit 143 is configured to obtain tumor three-dimensional image data, and determine a feature response result of a pixel point in an image to be corrected in a response direction according to the tumor three-dimensional image data, where the feature response result includes a scale parameter of a standard tumor three-dimensional image;
the three-dimensional image reconstruction unit 144 obtains the denoised three-dimensional image of the tumor, and determines the optimal characteristic response result through a non-classical receptive field edge detection algorithm to obtain a reconstructed three-dimensional image of the tumor.
In this embodiment, in operation, the positioning data obtaining unit 141 obtains the three-dimensional position and angle information of the tumor target area sent by the tumor three-dimensional space positioning unit 150 of the patient, the positioning data input unit 142 inputs the three-dimensional position and angle information of the tumor target area, executes a tumor state model, and establishes a tumor three-dimensional image, the three-dimensional image denoising unit 143 obtains tumor three-dimensional image data, then determines a feature response result of a pixel point in the image to be corrected in a response direction according to the tumor three-dimensional image data, obtains a denoised tumor three-dimensional image, and determines an optimal feature response result through a non-classical receptive field edge detection algorithm, so as to obtain a reconstructed tumor three-dimensional image.
In a further preferred embodiment of the present invention, as shown in fig. 4, the tumor target ablation module 200 comprises:
a tumor state acquiring unit 210, configured to acquire a real-time tumor state to be ablated, where the real-time tumor state includes a tumor ultrasound image acquired by the tumor detector and a simulated tumor three-dimensional image;
an ablation scheme traversing unit 220, configured to traverse the tumor pathology database step by step, and generate an ablation scheme library corresponding to the tumor target region at the patient feature position;
the ablation result derivation unit 230 loads the ablation scheme library of the tumor target region, screens the recommended ablation scheme for the corresponding patient, and pushes the recommended ablation scheme for the corresponding patient.
In this embodiment, the specific process of deriving the ablation plan by the ablation result deriving unit 230 is as follows:
the result export device obtains the result export request of the ablation scheme traversal unit 220, and then obtains the key rule parameters required for obtaining the result export, where the key rule parameters may be the main key for exporting the formatting rules of the ablation scheme, and then extracts the ablation scheme library associated with the key rule parameters through the main key, and the ablation scheme library stores ablation scheme configuration files, and the ablation scheme configuration files include, but are not limited to, field information, character set information, directory information, sq l information, file types, and the like, where the fields include, but are not limited to, field information character strings, numbers, different types of dates, and the like.
In a further preferred embodiment of the present invention, as shown in fig. 5, the method for establishing the tumor pathology database specifically includes:
step S101, collecting existing pathological data of a tumor patient, wherein the pathological data of the tumor patient records the diagnosis time and the diagnosis confirmed data of the patient, and the diagnosis confirmed data of the patient comprises the age, the sex, the blood test, the urine test, the operation scheme, the hospitalization time and the rehabilitation follow-up medical characteristic data of the patient;
step S102, acquiring collected pathological data of a patient, and classifying and summarizing the pathological data of the patient to obtain a treatment data set of the patient;
step S103, a Cox regression analysis method and a machine learning algorithm are adopted to construct an executed post-operation effect prediction model of each group of patient treatment data sets, the post-operation effect prediction model is trained, and a Cox regression analysis method model and a machine learning algorithm model containing effective post-operation effect models are screened out.
In a further preferred embodiment of the present invention, as shown in fig. 6, the tumor ablation cooling module 300 comprises:
the real-time ablation data acquisition unit 310 is used for acquiring real-time ablation data of the microwave tumor ablation instrument, wherein the real-time ablation data of the microwave tumor ablation instrument comprises the temperature of an ablation needle and the real-time temperature of a tumor target area;
the simulated thermal field model obtaining unit 320 takes the real-time ablation data of the microwave tumor ablation instrument as input to generate a simulated thermal field model architecture tree, and the simulated thermal field model architecture tree contains the real-time temperature of the key region of the tumor target region.
In this embodiment, the real-time temperatures of different positions of the patient's tumor target area can be simulated in real time through the simulation thermal field model architecture tree, for example, the temperature simulation of different positions of the same tumor target area of the patient and the temperature change of different time periods of the same position of the tumor target area are monitored through the real-time temperature simulation, and the tumor ablation efficiency is improved.
An ablation cooling request obtaining unit 330, configured to obtain an access request of a doctor end, where the access request includes a unique doctor end identifier and a doctor end access password;
in the embodiment, the doctor-side access password includes but is not limited to facial information of a doctor, fingerprint information of the doctor, and a dynamic or static verification code of the doctor, and leakage of privacy of a patient is avoided by setting the access password.
And the tumor target cooling execution unit 340 is used for verifying the unique identifier of the doctor end and the access password of the doctor end, loading a tumor target cooling scheme, and modifying the temperature of the ablation needle and the tumor target.
In a further preferred embodiment of the present invention, as shown in fig. 7, the tumor target cooling performing unit 340 comprises:
a historical cooling data storage module 341 configured to store historical cooling data and generate a historical cooling data set;
a cooling scheme importing module 342 for acquiring a historical cooling scheme corresponding to the historical cooling data;
and a cooling plan executing module 343, which trains according to the historical cooling plan, and edits the historical cooling plan or adds a cooling plan according to the tumor type of the target region.
In a further preferred embodiment of the present invention, as shown in fig. 8, the ablation effect evaluation module 400 is further included, and the ablation effect evaluation module 400 includes:
the tumor target area ablation calculating unit 410 is used for calculating the ablation efficiency of the tumor target area based on the tumor three-dimensional image and an ablation needle connected with a microwave tumor ablation instrument;
the ablation effect display unit 420 is used for generating a virtual real-time ablation three-dimensional model at a doctor end and rendering the ablation three-dimensional model to a virtual tumor three-dimensional image;
and an ablation effect feedback unit 430, configured to output ablation information and an ablation effect in the physician-side display area based on the rendered virtual tumor three-dimensional image.
In this embodiment, the ablation effect evaluation module 400 is used for evaluating the ablation effect after tumor ablation, and provides effect analysis and evaluation for the patient and the doctor to assist the postoperative rehabilitation of the patient.
In a further preferred embodiment of the present invention, as shown in fig. 9, a method of cold-cycle microwave tumor ablation, the method of cold-cycle microwave tumor ablation comprises:
step S1, responding at least one group of tumor ablation requests;
step S2, executing the tumor ablation operation of the corresponding tumor target area, wherein the tumor ablation operation of the corresponding tumor target area is based on the operation of a microwave tumor ablation instrument;
step S3, the tumor ablation cooling module 300 acquires the operation state of the microwave tumor ablation instrument, executes the cooling work of the microwave tumor ablation instrument according to the operation state of the microwave tumor ablation instrument, and pushes the cooling work to the tumor state simulation module 100;
and step S4, evaluating the ablation effect after tumor ablation, providing effect analysis and evaluation for the patient and the doctor, and assisting the postoperative rehabilitation of the patient.
In a further preferred embodiment of the present invention, as shown in fig. 10, the implementation method for responding to at least one group of tumor ablation requests specifically includes:
step S201, acquiring a preoperative pathological state of a patient;
step S202, receiving a matching request sent by a multi-channel matching device according to a preset rule;
step S203, screening the optimal tumor state model from the corresponding tumor state model storage system based on the matching request, and acquiring the identification code of the optimal tumor state model;
step S204, obtaining a tumor state model establishing instruction;
and S205, positioning the target region of the tumor to be ablated by the patient, connecting the patient with a microwave tumor ablation instrument, acquiring an ultrasonic image of the target region of the tumor by the microwave tumor ablation instrument, and determining three-dimensional position and angle information of the target region of the tumor based on the acquired ultrasonic image.
In summary, the invention provides a cold-circulation microwave tumor ablation system, in the embodiment of the invention, the tumor state simulation module 100 is arranged, and the tumor state simulation module 100 can form a tumor state display area at a doctor end, so that the doctor and the patient can observe the real-time state of the tumor in the patient conveniently, the tumor can be conveniently ablated, and the patient can be recovered conveniently.
It should be noted that, for simplicity of description, the above-mentioned embodiments are described as a series of acts, but those skilled in the art will recognize that the present invention is not limited by the order of acts, as some steps may occur in other orders or concurrently in accordance with the invention. Further, those skilled in the art should also appreciate that the embodiments described in the specification are preferred embodiments and that the acts and modules referred to are not necessarily required by the invention.
In the embodiments provided in the present application, it should be understood that the disclosed apparatus may be implemented in other ways. For example, the above-described embodiments of the apparatus are merely illustrative, and for example, the above-described division of the units is only one type of division of logical functions, and other divisions may be realized in practice, for example, a plurality of units or components may be combined or integrated into another system, or some features may be omitted, or not executed. In addition, the shown or discussed coupling or communication connection between each other may be an indirect coupling or communication connection between devices or units through some interfaces, and may be in a telecommunication or other form.
The units described as separate parts may or may not be physically separate, and parts displayed as units may or may not be physical units, may be located in one place, or may be distributed on a plurality of network units. Some or all of the units can be selected according to actual needs to achieve the purpose of the solution of the embodiment.
The above examples are only used to illustrate the technical solutions of the present invention, and do not limit the scope of the present invention. It is to be understood that the described embodiments are merely exemplary of the invention, and not restrictive of the full scope of the invention. All other embodiments, which can be derived by a person skilled in the art from these embodiments without making any inventive step, fall within the scope of the present invention. Although the present invention has been described in detail with reference to the above embodiments, those skilled in the art may still make various combinations, additions, deletions or other modifications of the features of the embodiments of the present invention according to the situation without conflict, and thus, different technical solutions that do not substantially depart from the spirit of the present invention may be obtained, and these technical solutions also belong to the scope of the present invention.
Claims (10)
1. A cold-cycle microwave tumor ablation system, comprising:
the tumor state simulation module is used for responding to at least one group of tumor ablation requests, the tumor ablation requests comprise tumor treatment information and predicted ablation results, and the tumor state simulation module is also used for forming a tumor state display area at a doctor end;
the tumor target area ablation module is used for executing tumor ablation operation of the corresponding tumor target area, and executing the tumor ablation operation of the corresponding tumor target area based on operation of a microwave tumor ablation instrument;
the tumor ablation cooling module acquires the operation state of the microwave tumor ablation instrument, executes the cooling work of the microwave tumor ablation instrument according to the operation state of the microwave tumor ablation instrument and pushes the cooling work to the tumor state simulation module.
2. The cold-cycle microwave tumor ablation system according to claim 1, wherein the tumor status simulation module comprises:
a patient pathological state acquisition unit for acquiring a preoperative pathological state of a patient, wherein the preoperative pathological state of the patient comprises a preoperative tumor pathological image of the patient and a clinical diagnosis result of the patient;
the tumor target area matching unit is used for receiving a matching request sent by the multi-channel matching equipment according to a preset rule, wherein the matching request carries a current tumor position, current patient body function parameters and a patient tumor identification code;
the tumor state model establishing unit is used for screening the optimal tumor state model from the corresponding tumor state model storage system based on the matching request and acquiring the identification code of the optimal tumor state model;
and the tumor state imaging unit acquires a tumor state model establishing instruction, wherein the tumor state model establishing instruction comprises an identification code containing the tumor state model.
3. The cold-cycle microwave tumor ablation system of claim 2, wherein the tumor status simulation module further comprises:
the patient tumor three-dimensional space positioning unit is used for positioning a target area of a tumor to be ablated by a patient, is connected with the microwave tumor ablation instrument, acquires an ultrasonic image of the target area of the tumor through the microwave tumor ablation instrument, and determines three-dimensional position and angle information of the target area of the tumor based on the acquired ultrasonic image.
4. The cold-cycle microwave tumor ablation system according to claim 3, wherein the tumor status imaging unit comprises:
the positioning data acquisition unit is used for acquiring the three-dimensional position and angle information of the tumor target area sent by the patient tumor three-dimensional space positioning unit;
the positioning data input unit is used for inputting the three-dimensional position and angle information of a tumor target area, executing a tumor state model and establishing a tumor three-dimensional image;
the three-dimensional image denoising unit is used for acquiring tumor three-dimensional image data and determining a characteristic response result of a pixel point in an image to be corrected in a response direction according to the tumor three-dimensional image data, wherein the characteristic response result comprises a scale parameter of a standard tumor three-dimensional image;
and the three-dimensional image reconstruction unit is used for acquiring the tumor three-dimensional image subjected to noise reduction, and determining the optimal characteristic response result through a non-classical receptive field edge detection algorithm to obtain a reconstructed tumor three-dimensional image.
5. The cold-cycle microwave tumor ablation system of any one of claims 1-4, wherein the tumor target ablation module comprises:
the tumor state acquisition unit is used for acquiring a real-time state of a tumor to be ablated, wherein the real-time state of the tumor comprises a tumor ultrasonic image acquired by the tumor detector and a simulated tumor three-dimensional image;
the ablation scheme traversal unit is used for traversing the tumor pathology database step by step to generate a tumor target area ablation scheme library corresponding to the characteristic position of the patient;
and the ablation result derivation unit is used for loading the ablation scheme library of the tumor target area, screening the recommended ablation scheme of the corresponding patient and pushing the recommended ablation scheme of the corresponding patient.
6. The cold-cycle microwave tumor ablation system of claim 5, wherein the method of establishing the tumor pathology database specifically comprises:
collecting existing pathological data of tumor patients, wherein the pathological data of the tumor patients record the diagnosis time of the patients and the diagnosis confirmed data of the patients, and the diagnosis confirmed data of the patients comprise the age, the sex, the blood test, the urine test, the surgical plan, the hospitalization time and the rehabilitation follow-up medical characteristic data of the patients;
acquiring collected pathological data of a patient, and carrying out classified induction on the pathological data of the patient to obtain a treatment data set of the patient;
and (3) adopting a Cox regression analysis method and a machine learning algorithm to construct a post-operation effect prediction model of each group of patient treatment data sets, training the post-operation effect prediction model, and screening out a Cox regression analysis method model and a machine learning algorithm model which contain effective post-operation effect models.
7. The cold-cycle microwave tumor ablation system of claim 6, wherein the tumor ablation cooling module comprises:
the real-time ablation data acquisition unit is used for acquiring real-time ablation data of the microwave tumor ablation instrument, and the real-time ablation data of the microwave tumor ablation instrument comprises the temperature of an ablation needle and the real-time temperature of a tumor target area;
and the simulated thermal field model acquisition unit takes real-time ablation data of the microwave tumor ablation instrument as input to generate a simulated thermal field model architecture tree, and the simulated thermal field model architecture tree contains the real-time temperature of the key region of the tumor target region.
8. The cold-cycle microwave tumor ablation system according to claim 7, wherein the tumor ablation cooling module further comprises:
the ablation cooling request acquisition unit is used for acquiring an access request of a doctor end, wherein the access request comprises a unique doctor end identifier and a doctor end access password;
and the tumor target area cooling execution unit is used for verifying the unique identifier of the doctor end and the access password of the doctor end, loading a tumor target area cooling scheme, and modifying the temperature of the ablation needle and the tumor target area.
9. The cold-cycle microwave tumor ablation system of claim 8, wherein the tumor target cooling performing unit comprises:
the historical cooling data storage module is used for storing historical cooling data and generating a historical cooling data set;
the cooling scheme importing module is used for acquiring a historical cooling scheme corresponding to historical cooling data;
and the cooling scheme execution module trains according to the historical cooling scheme, edits the historical cooling scheme or adds a cooling scheme according to the target tumor type.
10. The cold-cycle microwave tumor ablation system according to any of claims 1-4, further comprising an ablation effect evaluation module, the ablation effect evaluation module comprising:
the tumor target area ablation calculation unit is used for calculating the ablation efficiency of the tumor target area based on the tumor three-dimensional image and an ablation needle connected with the microwave tumor ablation instrument;
the ablation effect display unit generates a virtual real-time ablation three-dimensional model at a doctor end and renders the ablation three-dimensional model to a virtual tumor three-dimensional image;
and the ablation effect feedback unit is used for outputting ablation information and an ablation effect in a doctor end display area based on the rendered virtual tumor three-dimensional image.
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| CN117653320A (en) * | 2024-02-02 | 2024-03-08 | 四川省肿瘤医院 | Brain tumor operation monitoring equipment |
| CN117653320B (en) * | 2024-02-02 | 2024-04-05 | 四川省肿瘤医院 | Brain tumor operation monitoring equipment |
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