CN114990202B - Application of SNP (Single nucleotide polymorphism) locus in evaluation of genome abnormality and method for evaluating genome abnormality - Google Patents

Application of SNP (Single nucleotide polymorphism) locus in evaluation of genome abnormality and method for evaluating genome abnormality Download PDF

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CN114990202B
CN114990202B CN202210903055.8A CN202210903055A CN114990202B CN 114990202 B CN114990202 B CN 114990202B CN 202210903055 A CN202210903055 A CN 202210903055A CN 114990202 B CN114990202 B CN 114990202B
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CN114990202A (en
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季序我
李哲
朱晓茹
吕然
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Beijing Pukang Ruiren Medical Laboratory Co ltd
Predatum Biomedicine Suzhou Co ltd
Precision Scientific Technology Beijing Co ltd
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Predatum Biomedicine Suzhou Co ltd
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Abstract

The invention discloses an application of SNP loci in evaluating genome abnormality and a method for evaluating genome abnormality. The SNP loci are biallelic high polymorphic loci which are approximately and uniformly distributed on a chromosome, and the minimum allele frequency of each SNP locus is distributed between 0.05 and 0.5; the density of each SNP site on the genome is 16.5 per million genome bases; the GC content of 250-350 nucleotides taking each SNP locus as the center is 40-60 percent; and each SNP locus conforms to the Hardy-Winberg equilibrium law and simultaneously satisfies the condition that the group differentiation coefficient is lower than 0.05. The genome abnormality evaluation result obtained by the technical scheme provided by the invention has higher precision, can discover more and more comprehensive genome abnormality conditions, can process the genome abnormality condition with unchanged chromosome structure, is more suitable for Chinese people, and is more accurate.

Description

Application of SNP (Single nucleotide polymorphism) locus in evaluation of genome abnormality and method for evaluating genome abnormality
Technical Field
The invention relates to the technical field of biology, in particular to application of SNP loci in genome abnormality evaluation and a method for evaluating genome abnormality.
Background
At present, the common methods for evaluating genomic abnormalities mainly include the following methods:
pathology-based and stain-based karyotyping methods. In this method, the morphology of the chromosome can be directly observed under a microscope to evaluate whether it is different from the normal state. The method can only observe specific abnormal phenomena in a large range, and has insufficient precision. For example, only the deletion of the entire chromosome broken arm can be seen. Furthermore, abnormalities in which the chromosome structure is not changed, such as a case where the structure of a certain chromosome is not changed but there are two paternal chromosomes and no maternally chromosomes, cannot be observed.
A digital karyotype analysis method based on whole genome sequencing. The method does not need dyeing, and compares the sequencing fragment with a reference genome through whole genome sequencing and biological information analysis to evaluate whether the genome region is uncovered or excessively covered so as to judge whether the chromosome is abnormal. This method has improved accuracy, but still cannot cope with the above-described abnormal condition in which the chromosome structure is not changed.
Methods for detecting loss of heterozygosity (LOH). The method judges whether the locus is homozygous or heterozygous by selecting the locus, thereby judging whether the LOH appears in the genome region of the sample. The method can detect the abnormal condition of the invariant chromosome structure, and the accuracy of detecting the genome abnormality can reach 1.5 million bases and above. However, the detection accuracy for a specific population such as Chinese is low.
Pathogenic mutation detection of BRCA1 and BRCA2 genes is adopted to indirectly judge whether tumor cells have genome abnormality. It is believed that pathogenic mutations in BRCA1 and/or BRCA2 genes result in genomic abnormalities, and thus may be used. However, not all genomic abnormalities of tumor cells are caused by pathogenic mutations in the BRCA1 and BRCA2 genes. In addition, many of the genomic abnormalities of tumor cells are related to germline and systemic mutations in HRR genes other than BRCA1 and BRCA2, and some of the tumor cells are related to other factors such as methylation of specific gene promoters, unknown biological factors, etc.
Disclosure of Invention
In order to solve the problems in the prior art, the invention provides the following technical scheme.
The first aspect of the invention provides the application of a group of SNP sites in evaluating genome abnormality or preparing a device for evaluating genome abnormality, wherein the SNP sites are biallelic high polymorphic sites which are approximately and uniformly distributed on a chromosome, and the group minimum allele frequency of each SNP site is distributed between 0.05 and 0.5; the density of each SNP site on the genome is 16.5 per million genome bases; the GC content of 250-350 nucleotides taking each SNP locus as the center is 40-60 percent; each SNP locus conforms to the Hardy-Winberg equilibrium law and simultaneously satisfies the condition that the group differentiation coefficient is lower than 0.05; the positions of the SNP loci on chromosome 1 include: 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respectively;
The positions of the SNP loci on chromosome 2 include: 27292,122431,161739,200660,243056,293678,321723,367425,400092,436586,475266,526090,570399,605176,631096,692988,760260,831753,853973,875088,906336,928227,1032391,1122702,1145849,1165492,1199406,1266967,1373953,1417139,1443882,1466315,1497263,1527878,1568095,1593387,1615604,1642183,1685741,1719225,1755283,1825706,1854155,1887612,1941381,2017599,2076034,2124704,2176620,2222518,2311558,2366592,2413613,2452752,2523695,2562049,2594808,2663703,2701281,2730145,2770960,2844858,2878725,2914545,2952894,3041036,3074135,3112538,3149534,3184432,3246091,3285710,3339350,3422387,3465209,3497379,3586394,3630306,3660935,3693369,3721936,3767740,3797720,3831615,3874954,3909652,3949298,3984417,4017519,4063012,4106768,4143227,4183969,4229844,4269683,4310803,4354172,4439191,4477180,4512657,4564303,4603143,4639509,4674138,4720476,4766860,4820445,4854206,4956786,4990233,5189443,5229906,5267786,5407127,5481277,5524242,5561291,5599148,5639478,5689263,5727933,5770591,5809326,5845958,5886370,5958411,5992952,6038843,6116943,6156766,6201006,6241481,6278775,6309802,6347298,6382756,6416300,6457173,6508167,6544901,6589430,6630081,6663965,6711016,6754298,6800268,6834951,6876910,6964031,7018587,7070933,7116627,7200450,7248535,7329252,7408549,7499243,7542181,7597902,7635350,7672401,7751506,7807966,7892997,7943737,8026586,8059219,8100542,8145495,8186054,8236012,8291214,8357729,8406744,8450902,8495388,8534666,8572064,8610811,8664788,8704714,8745848,8781776,8816879,8869174,8937465,8998542,9069410,9142741,9256922,9293202,9334071,9391860,9435529,9474225,9515171,9560041,9609465,9661058,9754888,9834028,9870523,9906036,9988666,10033925,10067722,10110847,10145645,10181936,10229870,10279799,10320724,10359973,10391347,10423352,10464587,10505908,10539592,10575737,10617864,10660171,10725719,10755723,10798679,10845252,10885216,10920025,10976684,11007163,11041643,11081840,11119473,11209311,11248621,11315701,11366754,11414223,11466513,11507523,11542271,11592550,11633399,11713093,11752635,11794582,11904743,11955140,11994504,12035353,12110137,12149681,12236963,12314981,12400863,12549345,12594052,12668856,12722925,12776303,12813880,12863714,12912691,13011640,13060469,13108894,13191608,13234044,13281946,13323409,13401964,13453834,13486259,13560792,13606710,13640247,13678509,13719517,13760758,13803963,13842654,13891614,13942346,13980506,14028049,14070715,14117150,14205065,14239328,14329563,14366029,14408975,14452162,14534383,14583646,14631053,14675545,14715326,14776011,14840335,14886927,14939193,14987901,15035729,15077706,15129417,15173428,15205072,15242003,15330128,15451817,15502079,15535863,15577295,15617783,15664358,15706348,15749324,15790696,15875511,15916127,15950915,15986820,16073001,16129205,16211456,16246931,16384926,16430103,16471805,16516329,16558319,16605057,16650557,16694457,16738826,16833116,16943918,16989419,17037439,17086682,17139835,17189031,17241991,17287889,17336703,17381960,17430041,17469820,17515404,17573122,17639349,17688915,17743335,17789154,17887895,17926003,17973076,18049884,18140299,18186452,18231406,18269910,18306370,18348367,18386311,18418031,18455676,18500108,18540970,18576923,18611670,18661261,18746003,18807172,18857113,18953476,19048581,19097114,19151859,19242839,19295598,19386794,19440475,19580276,19640652,19683765,19721249,19754742,19791601,19826727,19872476,19911615,19945532,20021837,20063586,20105849,20171748,20223890,20316340,20357305,20399933,20553394,20595470,20632642,20675601,20710517,20749060,20783119,20818764,20860230,20951720,21008757,21066088,21190107,21231073,21312113,21363359,21396363,21434371,21478243,21523713,21614211,21659886,21705873,21775454,21823078,21880816,21926547,21976803,22036363,22086113,22158541,22209161,22302863,22350170,22410990,22463836,22504069,22549037,22634121,22687414,22738580,22898564,22940731,22984559,23037481,23089876,23136361,23261569,23305933,23345922,23391102,23438675,23489382,23536067,23585444,23626322,23670522,23716626,23794168,23833918,23878113,23921608,23982419,24033584,24081421,24135813,24183529,24295853,24343144,24389111,24446213,24502597,24568463,24650263,24693806,24754009,24821207,24873730,24934842,24993930,25044417,25122268,25220152,25261009,25312007,25409844,25465282,25523541,25578533,25632196,25754235,25814484,25874667,25922898,25969261,26023052,26081786,26138401,26230790,26276633,26324995,26378322,26423414,26476229,26557822,26646482,26687875,26728245,26764855,26809181,26849196,26893073,26939229,27033787,27121650,27164854,27224209,27285781,27332154,27427402,27482090,27546932,27604589,27719744,27769997,27827136,27880990,27943382,28064959,28125063,28196311,28265878,28328469,28384271,28479369,28535803,28582459,28674193,28714907,28757023,28790553,28858905,28898112,28958603,29012201,29063510,29117782,29161079,29196549,29228618,29303779,29348211,29426507,29454901,29494081,29533152,29612495,29655990,29693207,29727015,29764122,29801421,29845124,29881235,29919831,29962998,30086066,30126846,30166117,30209074,30256594,30304618,30353692,30406830,30449072,30493049,30536071,30565291,30605906,3064574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97,241994130,242062779,242099322,242134052,242167146,242214126,242261864,242355406,242396852,242430994,242473262,242509828,242535751,242605809,242651996,242699935,242737930,242776689,242842090,242872883,242909723,242937084,242963185,243001279,243052200, respectively;
The positions of the SNP loci on chromosome 3 include: 85398,122620,159349,192951,229772,265878,293670,357478,386858,420563,452169,482015,556186,591835,629079,641644,652407,664057,705014,742023,836863,957683,1034572,1067554,1106129,1132600,1167565,1199147,1233707,1299234,1325850,1350749,1382358,1419610,1455503,1486855,1514387,1547126,1580245,1615187,1643255,1668078,1698843,1721794,1753741,1788100,1819199,1849094,1879580,1928857,2008318,2037106,2076967,2115036,2152464,2195083,2231506,2267266,2308873,2375705,2408172,2439658,2482565,2519956,2607296,2716585,2747150,2776983,2811642,2835225,2864293,2902330,2937973,2974206,3008424,3038804,3071341,3104262,3188016,3278581,3308432,3339135,3377328,3444169,3490110,3518222,3554473,3588016,3630813,3696585,3731473,3766921,3793058,3825601,3860052,3903288,3947388,3979971,4010819,4043726,4084288,4127195,4163133,4201718,4242874,4321820,4361643,4429829,4468598,4509643,4581685,4622135,4657422,4697557,4766787,4806844,4893093,4929937,4969848,5004589,5081285,5113533,5148635,5183598,5233579,5273967,5305951,5343227,5402383,5434536,5474369,5510739,5541046,5580188,5608375,5681689,5715824,5751620,5788086,5840858,5909068,6007536,6040777,6089000,6120412,6157479,6191843,6226057,6258617,6328299,6362888,6407442,6446710,6488390,6526115,6572131,6618824,6651923,6723586,6752063,6787060,6825247,6873635,6963502,7123988,7158766,7199400,7243510,7291712,7335496,7370916,7400815,7433503,7476420,7509460,7550214,7591829,7631501,7676844,7708970,7787065,7823658,7863402,7895977,7958860,8029455,8076451,8159847,8192385,8233351,8274556,8319322,8364898,8416380,8453660,8544503,8589558,8632542,8670589,8707343,8729079,8771776,8805897,8915430,8954570,8991035,9033989,9072370,9112746,9203491,9254177,9303124,9328411,9378454,9430868,9486810,9543549,9634373,9680870,9742107,9794503,9880082,9924837,9962157,10042113,10079255,10106366,10183328,10248072,10321229,10362003,10406335,10442912,10492479,10665546,10758284,10796810,10842708,10887446,10931851,10977742,11061814,11104896,11151790,11197276,11236121,11284950,11336966,11387847,11481794,11522932,11604444,11640752,11673717,11703193,11743393,11819597,11859953,11933184,11960066,11992711,12079287,12168317,12216142,12259545,12297990,12345208,12395792,12443530,12484928,12525141,12565822,12605189,12638071,12715167,12757726,12796495,12831860,12906429,12943152,12994451,13042625,13081885,13121790,13162185,13202733,13240008,13280980,13312705,13357220,13398100,13442892,13479822,13598025,13635107,13673043,13740341,13778888,13823342,13943704,14003540,14063880,14117495,14156704,14251932,14290362,14324303,14362702,14398465,14436494,14519597,14566562,14608720,14651163,14696529,14737076,14782794,14831822,14878427,14953440,15003380,15102538,15150718,15182917,15278438,15325053,15361469,15402142,15445458,15484219,15520004,15570207,15661619,15701981,15798096,15849743,15901288,15941590,15990854,16029000,16067395,16113962,16190032,16315846,16359747,16459007,16589527,16627980,16753274,16797646,16841071,16888997,16936880,16986805,17092437,17149682,17189255,17297027,17345868,17455212,17513650,17703519,17813559,17860583,18017998,18082293,18137450,18191413,18247284,18299818,18404672,18457022,18519543,18570342,18617351,18658743,18743561,18780545,18861222,18913178,18965272,19024741,19148454,19258733,19313473,19429040,19500998,19572906,19629305,19688343,19745124,19793081,19885662,19930695,19971222,20007355,20047314,20120548,20158447,20195754,20236385,20275739,20321893,20359744,20401600,20445437,20487378,20519918,20570352,20608960,20700544,20741611,20776569,20821600,20868543,20908350,20954311,21001549,21081292,21118190,21164127,21198099,21244087,21292640,21336127,21373177,21422263,21459354,21490154,21525924,21620699,21653380,21690066,21729643,21761052,21793016,21820206,21852247,21935869,21962770,21988749,22015139,22048052,22078057,22110830,22139124,22170312,22197207,22231231,22269188,22303740,22341338,22383570,22421263,22459532,22501301,22544898,22608641,22644689,22693474,22725948,22773519,22825701,22879291,22918704,22957240,23005640,23051547,23113619,23152463,23224990,23271602,23315895,23367021,23414207,23511224,23646642,23691547,23732047,23769077,23805036,23848336,23970695,24004522,24048679,24099794,24152386,24192427,24231351,24270401,24304085,24350299,24443213,24494308,24534311,24632808,24670695,24711945,24747070,24782729,24818629,24857987,24904344,24939147,24975241,25010579,25037722,25074918,25115413,25150172,25184389,25214273,25249631,25288934,25327020,25364777,25403207,25435001,25475575,25513249,25549386,25586638,25626640,25728744,25784644,25838680,25890495,25939205,25992832,26042744,26098681,26150748,26205926,26250572,26303642,26363627,26421172,26509415,26544725,26575139,26618499,26655743,26693915,26743491,26786159,26826444,26874715,26961874,26994882,27046234,27079935,27113347,27148558,27213170,27254843,27299830,27343549,27433911,27487386,27527307,27569582,27616415,27687903,27728597,27821328,27866220,27905669,27943615,27986865,28027538,28071840,28117982,28158825,28211885,28259604,28317010,28374464,28435177,28506980,28572040,28633671,28801319,28843618,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respectively;
The positions of the SNP loci on chromosome 4 include: 36457,56076,80367,124902,182332,226937,272579,320897,361651,407393,452065,499439,535739,583034,628315,665779,739141,769298,810507,883039,920972,970377,1011417,1049875,1114351,1161798,1240810,1278004,1306886,1373622,1406658,1496783,1537914,1567158,1605843,1634784,1664874,1780419,1811328,1935055,1998120,2054055,2106765,2161429,2194374,2244674,2288238,2366664,2398055,2423366,2456802,2504195,2595468,2645478,2741679,2857374,2908782,2948514,2991526,3028401,3068482,3164628,3220761,3261763,3298395,3340889,3382389,3434167,3473650,3494228,3517485,3549038,3571181,3581893,3593301,3602070,3610486,3625606,3634306,3656013,3683470,3714836,3746318,3782455,3812631,3833120,3892445,3925213,3952815,3972887,4002998,4036180,4057717,4076723,4111202,4137752,4160310,4183878,4207215,4228738,4250241,4277847,4305537,4335824,4366950,4440539,4495118,4543407,4582183,4627958,4666770,4701962,4741418,4786670,4860254,4889621,4932445,4965462,5003283,5037445,5081995,5108497,5144868,5180055,5212544,5251594,5282794,5310453,5344472,5378053,5410837,5442765,5474386,5525897,5562539,5604800,5636113,5667134,5706091,5762623,5799547,5858579,5930920,6023171,6056325,6090641,6128624,6161577,6197404,6271416,6356557,6389642,6416861,6452814,6484168,6527252,6603943,6637273,6705590,6738935,6767566,6818015,6869307,6908751,6949223,6987446,7073187,7109184,7140918,7169275,7203849,7231418,7263980,7304496,7330321,7363331,7392523,7415699,7440604,7468947,7487800,7511012,7537063,7571761,7610416,7666722,7725585,7756195,7782804,7840332,7868217,7896213,7922096,7955294,7990930,8029018,8097789,8136641,8177203,8215226,8246502,8312738,8338034,8372856,8403533,8451179,8494089,8559688,8588179,8610899,8644405,8682821,8715672,8933168,9034510,9111280,9184457,9419658,9446609,9480019,9515883,9537431,9564484,9585071,9606018,9636355,9702790,9733115,9766886,9800679,9843356,9920086,9954238,9982917,10017979,10052817,10089253,10121012,10136685,10152935,10176594,10198514,10231237,10260765,10290420,10320891,10355396,10391902,10437334,10480591,10514681,10599205,10642159,10706970,10737954,10997737,11037998,11082149,11124523,11243343,11280398,11318311,11368670,11414198,11450699,11480557,11516449,11546396,11588899,11620694,11665013,11706820,11746643,11769076,11813105,11850401,11884465,11919586,11950395,11989859,12035048,12082491,12112707,12193889,12275587,12310722,12358940,12409447,12465168,12512865,12553096,12588094,12624701,12653988,12683297,12727586,12765282,12799832,12843654,12888358,12929066,12967195,13009049,13096420,13141039,13193386,13237029,13293417,13336573,13391329,13449807,13504752,13554557,13606027,13661643,13707225,13785739,13830615,13915104,14007710,14050263,14091440,14130567,14168299,14206434,14363148,14395094,14476568,14509817,14534626,14566932,14604890,14691717,14728549,14771119,14811600,14840518,14874138,14956607,15007988,15063390,15114305,15159192,15204853,15245140,15293023,15334214,15388838,15490752,15555221,15615479,15660184,15824974,15874537,15915388,15961555,16000542,16041619,16088567,16132084,16169755,16217627,16265834,16307516,16353893,16403682,16444413,16493698,16542294,16592117,16641382,16691200,16736331,16778299,16824435,16872076,16914832,16961656,17022015,17062007,17105777,17139437,17228148,17273023,17308473,17346374,17425937,17460970,17489883,17530699,17563687,17604802,17672465,17706071,17754729,17808337,17876943,17939302,18046636,18096948,18148869,18199611,18252106,18290930,18340461,18394023,18442406,18487049,18534169,18632463,18670863,18754700,18789221,18842624,18895094,18951799,19007280,19058515,19159497,19259080,19300189,19348177,19392182,19463717,19504786,19543063,19588900,19632142,19681035,19732689,19782712,19899705,19950098,20006151,20058664,20083052,20119727,20156709,20197183,20240093,20286490,20332458,20391615,20485321,20579306,20634072,20685544,20732701,20775383,20853948,20898558,20940550,20983806,21027322,21064253,21104021,21137001,21178999,21217985,21293490,21333298,21410659,21455256,21487844,21517194,21557180,21596543,21640489,21686957,21786688,21818459,21857425,21940697,21992543,22047433,22089812,22189941,22243808,22290611,22336096,22384063,22425837,22468621,22502130,22570233,22731822,22775690,22816662,22873033,22933965,22989505,23093028,23154778,23246187,23328370,23381513,23425588,23469584,23516403,23561069,23597396,23631652,23674005,23750569,23789477,23830741,23875589,23956205,24000544,24041628,24081446,24120953,24157323,24243483,24280371,24324927,24415092,24549927,24600388,24640911,24676440,24718497,24760535,24797566,24844929,24883062,24927682,25045341,25080036,25122890,25176277,25228583,25274171,25357164,25406189,25439633,25582496,25648141,25687153,25718984,25751278,25794583,25838901,25888370,25938806,26014228,26048141,26094992,26144084,26188992,26230326,26275336,26316816,26356092,26409537,26452301,26488853,26523592,26567378,26753223,26814210,26911129,27079874,27172472,27208505,27250649,27294111,27525746,27564839,27604705,27643547,27685167,27752434,27785567,27867912,27909347,27956188,27993916,28038705,28079899,28151913,28193573,28259975,28304630,283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The positions of the SNP loci on chromosome 5 include: 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The positions of the SNP loci on chromosome 6 include: 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6695,166920113,166953012,166993009,167032361,167071948,167148204,167183881,167213777,167245665,167273761,167318323,167392527,167424293,167456036,167505548,167544464,167584647,167620431,167641005,167674303,167691342,167714737,167742636,167776834,167811787,167844197,168093726,168198522,168274042,168326684,168391985,168416272,168445020,168504184,168534170,168557632,168645267,168678889,168706362,168738643,168774656,168799631,168834662,168883406,168915660,168944930,168973265,168995544,169013720,169035322,169060658,169097222,169131335,169169092,169202643,169233339,169247748,169266997,169293930,169313513,169334697,169365193,169395027,169434020,169471271,169508634,169541179,169576662,169607718,169636624,169712830,169752931,169867207,169916583,169958850,170025492,170065117,170173967,170208403,170249889,170364566,170398825,170428032,170455906,170496430,170529253,170553895,170579994,170625298,170664813,170703743,170727677,170758245,170778521,170845354,170888363,171009273, respectively;
The positions of the SNP loci on chromosome 7 include: 63018,96312,117442,143945,172014,199624,220023,341524,511617,594686,686134,730834,828626,904368,933749,954862,977429,1017698,1049123,1072146,1100931,1132685,1157795,1189279,1210688,1242328,1275578,1310386,1334533,1366777,1410019,1457450,1495283,1570126,1610365,1652801,1691210,1792413,1852166,1888758,1918941,1944205,1975176,2008725,2048017,2124355,2200973,2240657,2280845,2315950,2403128,2430624,2473125,2512252,2546631,2585570,2617042,2644589,2673288,2742336,2764724,2836836,2874835,2938109,2966869,3001173,3033975,3094488,3127660,3155668,3185260,3242371,3272227,3334836,3359708,3387838,3420443,3453333,3519885,3555462,3629521,3662146,3754653,3791115,3821953,3888321,3914875,3950836,4026009,4060005,4086123,4117436,4146288,4178823,4210874,4238412,4266583,4303279,4331707,4367133,4398657,4425837,4451320,4513330,4539982,4575849,4605654,4657654,4744796,4777207,4810712,4842577,4939038,4977659,5014519,5053287,5095577,5193946,5288168,5321113,5351444,5424636,5470363,5500145,5536379,5568863,5605445,5640871,5681903,5725443,5770400,5868561,5897906,5996104,6045597,6083951,6218003,6262355,6305817,6347041,6379537,6440883,6470206,6503384,6545369,6593496,6674724,6710094,6720384,6760203,6857441,6887323,6911082,6944645,6974952,6996353,7015797,7035605,7070743,7102584,7128515,7161793,7205854,7242686,7269777,7309885,7343138,7377368,7408659,7446846,7487308,7533479,7583953,7694722,7732347,7771121,7806815,7844340,7875856,7909659,7946590,7988650,8075115,8116836,8154136,8189629,8225224,8262922,8309275,8350404,8391115,8436060,8479629,8520389,8558959,8600498,8639678,8674306,8699560,8732406,8823447,8895484,8971784,8995414,9030356,9087523,9116799,9147011,9179684,9212596,9251214,9292876,9329824,9374548,9423414,9473970,9515348,9553037,9591611,9625115,9651917,9689761,9719759,9809503,9876688,9917581,9958144,9995571,10032228,10070089,10141996,10178822,10222749,10293191,10368770,10404393,10449020,10516005,10552259,10592286,10629615,10673337,10725451,10780738,10831607,10873865,10948631,10987457,11031114,11072214,11115578,11163459,11208989,11241635,11281957,11316527,11343074,11379953,11422942,11472736,11523249,11559288,11590583,11618675,11665971,11750617,11786624,11822682,11862342,11906401,11932615,11974451,12007576,12037234,12070560,12102313,12133937,12171723,12200287,12229796,12260546,12290724,12323936,12351245,12377937,12407582,12482517,12514636,12543622,12583153,12616242,12656390,12695442,12761698,12785780,12825805,12900316,12934776,12963866,13010649,13049523,13128696,13163517,13196721,13236232,13271297,13304611,13336929,13378131,13421817,13466283,13508540,13547757,13582614,13661045,13692529,13798406,13836721,13886700,13919741,13958662,13997159,14030119,14110358,14150643,14196943,14238703,14276766,14306522,14345939,14395580,14440441,14482710,14557048,14599259,14641395,14685825,14729087,14808055,14843912,14884744,14922349,14996167,15033129,15065798,15107479,15139814,15179443,15225415,15260042,15304266,15342244,15377318,15407982,15436505,15473921,15509221,15551301,15600816,15635022,15668307,15718461,15760654,15803580,15853046,15892633,15926770,15964754,16008390,16049458,16086674,16126723,16170530,16218545,16263161,16308329,16349864,16386034,16423819,16455330,16502332,16538967,16577376,16624693,16661694,16706051,16747711,16777333,16809170,16842760,16877706,16908741,16942661,16977505,17012944,17053030,17090223,17129241,17183806,17229862,17285635,17357630,17468811,17504506,17545170,17574553,17610758,17642946,17679434,17711759,17743563,17814607,17928480,17978343,18058852,18161620,18306410,18350296,18402849,18449665,18497011,18552373,18605487,18647876,18697666,18748952,18792116,18828964,18864122,18912137,18950118,19000113,19046946,19089438,19137857,19177639,19219778,19317754,19362075,19436443,19483054,19522027,19546810,19590347,19622050,19657122,19697067,19746541,19788301,19865278,19903503,19934505,19969897,20003753,20047875,20092407,20218520,20263578,20301688,20336810,20384620,20472512,20509672,20549389,20647703,20687181,20716213,20755114,20910451,20967325,21015161,21061980,21147557,21188774,21237468,21278141,21355243,21397981,21441078,21482567,21519608,21563052,21595155,21633505,21670593,21708050,21775076,21807773,21838330,21868394,21902986,21938469,22012548,22046080,22077458,22119972,22155760,22199634,22252165,22349769,22392027,22426826,22465557,22501109,22539421,22589911,22635725,22702016,22745623,22821881,22857589,22889410,22923649,23025891,23072077,23117765,23165119,23205853,23251746,23294648,23334502,23389444,23484260,23532235,23582052,23628380,23730246,23821784,23859374,23945976,23989900,24071397,24159020,24197906,24276803,24308281,24380444,24417090,24452713,24495798,24582398,24634797,24682520,24726752,24763467,24807405,24858444,24904868,25033198,25078712,25243976,25322653,25363617,25445040,25475585,25515926,25562381,25602216,25637958,25696093,25739360,25784462,25828569,25878124,25978571,26024687,26079330,26125625,26171823,26222973,26261143,26315472,26358318,26391892,26487587,26573960,26606005,26640665,26674108,26726320,26832022,26880519,26936869,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respectively;
The position of the SNP locus on chromosome 8 comprises: 186271,220987,240492,266757,294720,323671,350137,390206,423879,453857,486343,525112,558379,582945,613773,636539,660944,695943,734398,758565,831649,876613,915745,943496,971298,994759,1026619,1053621,1085374,1114974,1135242,1152074,1168708,1191510,1265149,1287645,1355919,1376122,1402566,1423482,1452615,1478325,1510233,1536758,1563428,1588509,1611169,1641167,1675219,1707272,1776376,1798179,1817799,1837443,1863383,1901110,1927246,1955393,1986262,2008847,2033642,2051979,2077072,2091879,2111830,2136501,2159512,2181472,2207709,2221208,2238977,2264525,2284777,2307223,2362100,2455325,2485492,2512560,2537271,2566825,2596341,2630935,2684495,2716359,2742089,2769298,2826822,2861030,2889651,2912529,2938619,2964503,2996150,3029672,3082618,3134712,3156668,3171662,3193785,3213092,3234119,3256288,3276650,3299369,3323760,3344541,3363441,3386424,3408229,3422471,3442377,3460557,3479964,3498904,3519063,3538528,3559268,3572647,3588760,3605823,3626217,3643120,3661040,3679619,3699344,3737310,3757018,3776571,3795261,3813492,3830442,3847994,3867910,3900551,3915562,3935720,3956297,3992617,4022412,4054448,4075464,4094658,4119457,4142987,4161050,4174631,4193502,4233767,4254058,4275087,4292832,4308183,4324194,4349565,4382286,4410318,4438436,4489464,4514626,4601254,4622263,4644553,4665649,4690488,4721066,4752088,4789067,4803200,4823714,4846986,4877391,4903970,4926972,4955782,4979961,5047528,5073843,5098285,5127400,5150901,5169199,5189283,5213378,5235928,5255235,5283533,5307217,5335495,5362900,5391562,5412893,5438215,5463043,5488335,5509574,5533627,5555962,5579775,5601342,5619062,5643720,5668625,5695063,5725285,5751753,5778414,5803576,5825826,5846504,5883949,5911954,5934489,5960848,5987937,6011141,6036358,6063568,6085381,6132391,6157388,6191167,6215788,6236602,6259136,6281138,6312346,6337080,6364575,6414013,6438204,6464103,6489190,6516722,6544798,6574104,6607821,6635600,6664058,6716282,6769704,6797103,6826140,6888488,6968854,7005008,7216021,7332979,7763738,8004693,8077066,8101188,8136280,8170081,8205287,8244991,8275605,8302079,8329260,8363740,8392274,8427415,8462948,8492809,8522632,8557526,8586386,8612786,8643992,8673320,8709716,8742067,8773510,8803696,8844117,8870543,8898016,8963610,9039838,9072121,9101373,9129826,9159630,9191554,9251693,9282466,9317106,9356802,9393831,9431033,9467624,9510067,9561945,9597824,9634944,9669885,9706115,9735594,9773359,9813236,9861916,9937455,9977476,10016471,10052546,10085359,10112595,10139470,10207418,10247816,10280039,10311704,10342122,10373694,10401785,10432909,10469030,10542007,10571465,10606954,10638401,10668637,10697649,10744284,10789345,10828598,10860846,10896425,10931497,10967122,11001951,11036975,11076418,11110753,11148157,11186674,11226071,11267737,11299256,11360494,11450783,11489579,11523106,11567992,11610567,11634650,11686487,11705779,11740508,11771619,11791320,11816929,11849745,11875316,11929422,12007364,12239662,12312540,12407103,12424140,12443223,12481030,12508172,12531178,12559874,12630974,12662403,12697757,12729545,12763577,12797831,12827931,12855570,12882634,12903974,12927207,12960335,12995420,13023950,13061579,13140305,13170576,13194053,13222549,13251422,13315983,13345414,13377700,13405541,13436422,13462198,13513544,13537834,13559526,13584946,13604103,13623608,13646455,13666813,13688497,13713791,13733644,13784153,13803680,13824535,13882528,13905752,13925152,13957144,13987423,14023484,14057645,14083622,14108630,14136161,14161272,14195730,14231670,14257880,14281719,14311502,14341787,14366045,14424429,14456327,14484778,14505171,14534352,14567061,14596584,14631530,14672930,14707570,14750415,14791669,14833412,14896349,14932322,14962249,14996765,15024895,15084051,15120258,15151088,15184032,15214803,15237968,15268341,15291893,15318517,15354418,15380848,15411783,15448124,15480206,15512783,15546627,15583206,15616572,15646305,15669365,15687517,15706522,15730153,15780390,15807268,15837443,15871892,15913605,15940614,16025885,16052589,16089634,16121873,16161121,16212273,16253333,16297220,16344655,16373068,16406598,16441593,16481944,16519891,16555109,16586902,16617343,16648148,16735406,16773420,16815577,16842829,16900593,16942849,16990621,17031164,17065569,17114512,17157044,17190038,17222967,17251155,17307015,17334539,17358496,17385836,17416251,17443470,17462624,17485789,17533418,17556506,17586307,17618569,17644219,17700055,17726054,17748582,17810390,17847984,17883147,17911937,17936982,17975547,18006140,18034779,18064807,18090403,18124916,18153569,18190845,18215623,18243113,18300954,18328552,18430602,18458721,18484830,18546582,18578496,18617010,18650909,18679225,18715533,18757176,18794531,18822548,18852397,18919720,18947351,18981713,19080556,19113646,19145226,19177567,19260240,19296468,19332546,19397288,19462667,19497883,19532298,19570709,19607661,19642088,19725412,19767298,19809427,19838578,19876797,19920578,19955920,19995559,20028210,20104470,20138261,20181698,20221679,20260760,20295746,20330469,20361185,20397418,20438736,20515550,20557049,20589564,20625285,20667432,20788373,20852077,20889926,20930056,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respectively;
The positions of the SNP loci on chromosome 9 include: 39360,105953,164831,205297,245032,271822,333416,361818,392670,423004,459345,494342,557844,591562,618813,647999,667391,691376,724217,751121,780835,803851,834655,857511,880438,906052,935503,978265,1015337,1046495,1078694,1113688,1169543,1205747,1243967,1278833,1307782,1338005,1372889,1413166,1451966,1479100,1506101,1560678,1617277,1649782,1685741,1715256,1744771,1774821,1821515,1853425,1889540,1922303,1965646,2011345,2055697,2095958,2135494,2169898,2201807,2265003,2299042,2342966,2377823,2414851,2486550,2522475,2553112,2593528,2632315,2665492,2697979,2734539,2777770,2819410,2864224,2901344,2936285,3022592,3059740,3096420,3134294,3166207,3205480,3250753,3299728,3452551,3521236,3584112,3627626,3688610,3729256,3766582,3812356,3854070,3928151,3966486,4008212,4111864,4151884,4184065,4255384,4285088,4316407,4373432,4401005,4434012,4470855,4507192,4549314,4593157,4631675,4658662,4696927,4727775,4755298,4825979,4855912,4902317,4945746,4999323,5052359,5100733,5193277,5233373,5269575,5318703,5360766,5397662,5433388,5464376,5506429,5553541,5606709,5653758,5700010,5746646,5889205,5945312,5995523,6051358,6148072,6201575,6254567,6299810,6413904,6462215,6515920,6600377,6629939,6658080,6685019,6716511,6747799,6788012,6828441,6864636,6942522,7006663,7041039,7082397,7120851,7154851,7187974,7224722,7261450,7294617,7325806,7361595,7456295,7497097,7529861,7560844,7595374,7640694,7677376,7713039,7747510,7788633,7878626,7916560,7959752,8002270,8045999,8094390,8132480,8208952,8244384,8309392,8334420,8367692,8397775,8430892,8470268,8508597,8556602,8636983,8675050,8710109,8743408,8769885,8834563,8866527,8904596,8933267,8955740,9000935,9068928,9110552,9149546,9189926,9235410,9274259,9318688,9357065,9396251,9464912,9498018,9540907,9580946,9619605,9661211,9709808,9747105,9780049,9812087,9845152,9879623,9908756,9942685,9975058,10011536,10048205,10116005,10147116,10190773,10230141,10263623,10290056,10336685,10380125,10420097,10455033,10487367,10561559,10671848,10708866,10752338,10836932,10884513,10931834,10974159,11007684,11033665,11071160,11098475,11125902,11162510,11199226,11239025,11269531,11311022,11438424,11476113,11515414,11557876,11594486,11623933,11660080,11698942,11734433,11767921,11800746,11835319,11868796,11908303,11952128,11998261,12032864,12078769,12117309,12166969,12203061,12275962,12313945,12347724,12370472,12399142,12452348,12495286,12586806,12632288,12673731,12709441,12748587,12785073,12830941,12866358,12892306,12927866,12961551,13011791,13058128,13102063,13161000,13224887,13277534,13332878,13386175,13445508,13493036,13532112,13562874,13599352,13675371,13716005,13751764,13781570,13812637,13851213,13879957,13919583,14010312,14045800,14088346,14141703,14224301,14266746,14312400,14402079,14442529,14487611,14532789,14567207,14608670,14649882,14694816,14733642,14811009,14847780,14887606,14934720,14979843,15063368,15098525,15133328,15171759,15216293,15258922,15292455,15332701,15401044,15442541,15477436,15520755,15615321,15678259,15726267,15824541,15952258,16037030,16081813,16122631,16162525,16202674,16226780,16262884,16301484,16334986,16408826,16454714,16493143,16528611,16573486,16618001,16667341,16710899,16749782,16815861,16886487,16910898,16935343,16961173,16992122,17030305,17064226,17112944,17151510,17195804,17238393,17274815,17344907,17468106,17506823,17547664,17580292,17652883,17690174,17721401,17746569,17778061,17818007,17858434,17898857,17937633,17972120,18016573,18063949,18104533,18143954,18187511,18237789,18275275,18305489,18348274,18395119,18432139,18478894,18522832,18565216,18601951,18634268,18670579,18719142,18761687,18837987,18882257,18911778,18943380,18971932,19005829,19035850,19076313,19117038,19154738,19190629,19233679,19266141,19306663,19347663,19390407,19430459,19472080,19513554,19593235,19642524,19683409,19723243,19762691,19812437,19861933,19900013,19944652,19990073,20031656,20070944,20115057,20162853,20204823,20242344,20280828,20323424,20376023,20443334,20502104,20589530,20630614,20735804,20785784,20840240,20897424,20989643,21034163,21081822,21129739,21171823,21202867,21236589,21282578,21328806,21368666,21417570,21460710,21507183,21553178,21601812,21675670,21711815,21743288,21781867,21826463,21864552,21918203,21967676,22010412,22063019,22133984,22160768,22196508,22244294,22288403,22329580,22379411,22420204,22465207,22509658,22549535,22591196,22637057,22732903,22780966,22872321,22914592,22950406,22988063,23026272,23065716,23099607,23136745,23173989,23264340,23302726,23347980,23385738,23424567,23516909,23561054,23607571,23679709,23721349,23767047,23815595,23924422,23973389,24061320,24105279,24148652,24185915,24243377,24291960,24389265,24446133,24551983,24607643,24649916,24725322,24773842,24818504,24852695,24895277,24930442,24970615,25012405,25059297,25124412,25161718,25239583,25285076,25385116,25415713,25451237,25496001,25538406,25612202,25722614,25765616,25782400,25825227,25870079,25924324,25968015,25995534,26033758,26087831,26141431,26190855,26242441,26300424,26349577,26394764,26451025,26498623,26532846,26571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633,141063232,141084494, respectively;
The positions of the SNP loci on chromosome 10 include: 106126,137212,202527,261650,315732,390358,419916,444555,471339,501504,538317,574326,607922,678000,723150,761649,777642,807330,837450,881998,936873,991644,1061665,1132980,1170496,1205850,1234510,1270534,1307655,1343759,1376968,1407539,1434704,1494010,1515644,1551548,1583406,1605704,1626935,1651002,1675929,1705879,1738482,1765005,1851858,1917708,1977423,2046453,2101136,2172065,2207785,2278085,2310137,2344595,2371598,2399399,2433400,2466878,2504343,2535669,2562642,2625209,2656120,2694562,2730860,2766759,2794937,2829929,2874739,2914753,2954160,3039787,3071854,3096617,3121077,3146155,3163175,3180298,3212358,3246569,3276965,3409675,3453522,3487380,3521369,3605732,3658059,3735925,3770581,3803035,3837555,3869607,3906885,3940706,3965873,3988667,4021907,4062327,4103901,4140580,4168171,4218425,4251861,4364598,4404105,4525591,4555699,4597847,4630288,4657550,4696289,4740045,4784070,4824926,4886868,4915912,4961369,4995058,5027931,5056002,5090805,5129139,5151354,5179882,5214831,5252902,5325918,5363083,5397491,5471470,5510802,5546087,5619116,5647078,5681032,5712693,5802956,5842240,5886570,5958072,5991569,6021885,6052068,6079483,6112291,6150311,6182749,6211592,6238963,6265329,6301078,6341206,6373848,6454924,6488017,6527270,6564883,6611621,6687618,6726766,6764797,6807730,6846265,6913849,6973882,7009557,7038968,7081699,7117594,7149998,7194265,7239793,7274741,7312200,7361749,7404505,7445901,7490206,7523475,7555492,7588290,7622217,7686343,7721859,7756155,7795548,7877290,7917798,7969567,8065087,8099629,8123191,8150102,8183039,8217921,8249865,8283928,8321660,8362245,8397816,8464581,8550507,8582358,8658846,8702460,8740732,8781277,8897261,8945648,8983047,9023719,9058671,9094424,9132408,9171654,9213854,9259428,9306064,9349500,9452439,9512428,9553961,9612515,9671078,9796000,9857091,9910828,9955333,9991667,10029896,10065438,10104399,10140203,10220981,10262842,10300168,10326331,10370918,10422594,10510959,10556072,10592979,10629297,10668715,10718024,10758526,10800504,10844526,10892091,10979955,11033600,11084164,11158063,11197845,11239010,11275566,11308616,11346374,11388639,11418955,11456364,11492868,11543086,11656848,11699856,11730196,11759046,11821473,11858114,11896420,11928072,11957748,11999791,12047767,12087005,12161411,12206169,12253183,12294890,12324964,12426386,12499594,12533173,12566199,12598121,12663986,12743559,12778206,12807287,12836751,12869284,12893229,12941153,13001186,13032586,13069718,13103657,13134648,13169264,13211533,13250133,13281667,13313259,13348512,13433417,13473087,13511986,13554112,13599687,13642872,13683519,13714057,13741505,13772503,13808113,13832761,13859564,13896605,13926123,13959305,13989216,14028674,14093716,14131835,14166745,14235685,14273535,14306643,14344556,14378449,14415867,14440662,14476854,14512559,14552207,14592997,14623195,14661117,14757013,14800569,14829883,14863375,14918316,14965511,14995464,15027645,15098311,15134623,15170431,15214537,15257383,15298555,15342661,15450994,15522841,15548747,15583365,15616714,15656020,15698576,15745059,15785720,15829458,15887674,15943681,15988352,16025697,16113376,16150889,16187157,16232149,16271816,16313333,16348783,16383058,16419974,16444680,16477500,16515573,16553349,16591841,16626515,16674290,16710032,16742510,16779757,16818105,16849659,16877859,16921214,16965178,17063577,17144768,17181979,17222557,17259863,17298472,17331544,17397448,17424271,17466752,17507512,17542447,17587121,17702921,17740411,17793756,18358517,18397597,18436647,18470174,18663585,18702356,18770298,18808692,18847041,18889907,18975185,19004994,19045354,19088771,19127973,19173550,19246810,19387126,19426549,19459979,19490933,19519981,19551922,19627998,19662132,19762077,19793829,19828832,19875303,19912246,19943290,19988543,20080740,20120750,20155618,20199105,20239338,20282191,20318588,20352631,20429371,20471205,20509788,20547231,20624933,20661179,20740616,20780095,20819892,20892992,20934100,20975654,21012039,21058596,21143722,21187945,21236507,21277980,21356409,21394129,21445236,21528348,21615569,21647453,21697652,21749246,21809706,21873712,21996118,22061494,22277065,22339708,22463594,22564924,22629414,22689404,22738919,22791353,22833928,22872674,22910489,22950152,22995580,23044757,23137721,23185723,23237568,23328733,23469422,23528023,23580946,23631278,23677090,23717462,23755039,23795334,23883517,23922510,23976996,24018500,24101521,24135231,24187192,24226419,24268482,24312048,24415337,24467351,24502629,24547110,24593546,24637755,24675218,24764631,24807097,24850658,24904115,24967176,25028479,25078088,25124826,25166578,25197663,25240084,25285385,25367066,25417504,25460936,25523699,25577521,25641379,25668917,25709364,25739714,25784245,25829906,25917909,25956113,25994034,26024322,26063061,26110653,26154038,26182569,26221380,26273616,26315345,26346047,26366576,26421847,26471289,26516639,26549427,26589814,26617542,26657758,26696509,26733753,26768622,26814137,26857582,26874089,26924489,26938434,26961039,26984146,27016642,27063077,27112414,27144553,27179667,27215087,27233815,27265194,27314400,27360773,2739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The position of the SNP locus on chromosome 11 comprises: 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respectively;
The positions of the SNP loci on chromosome 12 include: 151272,222812,261839,292946,324670,362077,506893,540264,576541,606598,670743,698043,771785,813197,858536,903636,950683,987634,1021159,1088357,1129982,1177343,1209113,1382293,1425657,1465409,1503341,1587160,1614615,1646825,1683582,1722328,1759929,1804194,1853291,1981349,2023486,2113282,2151060,2198671,2234440,2290086,2334467,2440464,2482943,2574613,2619268,2663185,2759141,2799284,2852349,2932177,2975253,3046569,3084349,3125328,3183163,3212998,3240295,3340366,3372141,3401883,3434902,3478435,3579369,3621711,3665097,3711017,3795006,3843922,3875602,3913900,3968977,4011466,4088850,4129956,4173938,4225089,4268844,4311442,4349455,4392530,4471635,4543570,4589934,4698860,4737889,4869017,4916963,4951809,4990779,5035433,5083083,5123695,5158463,5201737,5245668,5325561,5374704,5431867,5472611,5522436,5618933,5705316,5773880,5858461,5916833,5997095,6032326,6061555,6093048,6147110,6180510,6217504,6252482,6286671,6317852,6357363,6396786,6432148,6458856,6491078,6526744,6563698,6631169,6672191,6779333,6826336,6861247,6908146,6935955,6983903,7024022,7067226,7115989,7178872,7284301,7334581,7376398,7420219,7482768,7544401,7595836,7653039,7709867,7748922,7793279,7832486,7870461,7907101,7948010,7972686,8041326,8075677,8144649,8176687,8227318,8278181,8328697,8364266,8385143,8408977,8446982,8479885,8543038,8576248,8611428,8661939,8703947,8739758,8783624,8825781,8871953,8920224,9004667,9037134,9087544,9135257,9188757,9297403,9349955,9428660,9474509,9504891,9536566,9565534,9614685,9666643,9731939,9766785,9813188,9853650,9889727,9964966,10010411,10087298,10124661,10161067,10204478,10252944,10289164,10322186,10417105,10501750,10532326,10571658,10600154,10645762,10681543,10712195,10760443,10802586,10844383,10887323,10933626,11076230,11158572,11173620,11183832,11203429,11213446,11224770,11232520,11241868,11275926,11284988,11316430,11349267,11393463,11442155,11485673,11560553,11601042,11674254,11715550,11765325,11807184,11849379,11891441,11930117,11974707,12019754,12088462,12130518,12166381,12198858,12228034,12263940,12317707,12365529,12419719,12455114,12565055,12594654,12635275,12687224,12734174,12777557,12826887,12870695,12908786,12952018,12989850,13032065,13067561,13104160,13149595,13195538,13254715,13361241,13402605,13449545,13497985,13535742,13576153,13611575,13651566,13734133,13775800,13833593,13873619,13926911,13967182,14015052,14065870,14109457,14153261,14201273,14251761,14293079,14368308,14413021,14456090,14498812,14601352,14648500,14696979,14793220,14840113,14885245,14984361,15037076,15075854,15112916,15148937,15227822,15270067,15310339,15366321,15430821,15566369,15610073,15654216,15690733,15734849,15842436,15903617,15964714,16020006,16069383,16124692,16172573,16232460,16273308,16329144,16409383,16453225,16494839,16528684,16575046,16622136,16674932,16737396,16811624,16874107,16930595,17052329,17117753,17186396,17247025,17302851,17359219,17462145,17510913,17556694,17596962,17643629,17695007,17740848,17782144,17936069,18028597,18082924,18127570,18182709,18233323,18279922,18331234,18379840,18423992,18470418,18527463,18571906,18609971,18666529,18717609,18769922,18845281,18886980,18932012,18980988,19028311,19077503,19116247,19169602,19216447,19256882,19309304,19351689,19404820,19546228,19582943,19622218,19654583,19691773,19779749,19809623,19850778,19920004,19988685,20023668,20063968,20114660,20159638,20183575,20230384,20278893,20317889,20358369,20406470,20453061,20498871,20547182,20588037,20634983,20731615,20774882,20813524,20855696,20927006,20959603,20990987,21019837,21057442,21131622,21167811,21207728,21252930,21339380,21376213,21415519,21456222,21495910,21545759,21593738,21624398,21750254,21796814,21828677,21936318,21988087,22036979,22094801,22152130,22186582,22224015,22260998,22304887,22356763,22403123,22442707,22491597,22549958,22630828,22688479,22750537,22808074,22860778,22902676,22943719,22988592,23025013,23127833,23217064,23312222,23426527,23567892,23624745,23677328,23733332,23781672,23826667,23872812,23922163,23969087,24014044,24063219,24117091,24152079,24190854,24228187,24267639,24311226,24356254,24400694,24435683,24475508,24514884,24557317,24596843,24643990,24697505,24749731,24801240,24891230,24930390,24962007,24995892,25042601,25087022,25120045,25156560,25193158,25230121,25306242,25354828,25396085,25439169,25476261,25513333,25551464,25582515,25620127,25666255,25703936,25754026,25794790,25840390,25896843,25939117,25984408,26023589,26130232,26167734,26205999,26245229,26297245,26338730,26382335,26424120,26462580,26561955,26605769,26687447,26737472,26775614,26824366,26875632,26925507,27009893,27057512,27109888,27164821,27215813,27311884,27359892,27403466,27503743,27550462,27600090,27636924,27683792,27731851,27774682,27812764,27909254,27986663,28036942,28083409,28126776,28167619,28208832,28249464,28300257,28347456,28354215,28354653,28410865,28478864,28538278,28587583,28640936,28705864,28851559,28959726,29028475,29067176,29112196,29151248,29274850,29360783,29406213,29443381,29485449,29542495,29582321,29632278,29674302,29712571,2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respectively;
The positions of the SNP loci on chromosome 13 include: 19045719,19188901,19230344,19300112,19325256,19354163,19386447,19420255,19447571,19484083,19524321,19560486,19595824,19627059,19644551,19651313,19670296,19720207,19806777,19880021,19919738,19939348,19961373,20036991,20097234,20221817,20266522,20310651,20438883,20476274,20565736,20616864,20671255,20701448,20743417,20778464,20810602,20850011,20917309,20946163,20982708,21052875,21087336,21121787,21164732,21210042,21255689,21337862,21436701,21481665,21513679,21569345,21604456,21641565,21679558,21711476,21753012,21794696,21834597,21875315,21905870,21944100,21989201,22039137,22115948,22158604,22298530,22336428,22372894,22415097,22446077,22546747,22580579,22659312,22707533,22753304,22791888,22901132,22948884,22990965,23041595,23079072,23124255,23161271,23200776,23241794,23281078,23344260,23383039,23455870,23489845,23523452,23541312,23594887,23631790,23697519,23764917,23823888,23861945,23888328,23939872,23978217,24019346,24061960,24097928,24135592,24300694,24345651,24388701,24460390,24490761,24517659,24543328,24577652,24612191,24639957,24673653,24703260,24738246,24771545,24800996,24841178,24876269,24914139,24947695,24975915,25008380,25065429,25137710,25183855,25252900,25286750,25327470,25368922,25493186,25526788,25556511,25588341,25617381,25688985,25725541,25767300,25803260,25850579,25891408,25973050,26005839,26044668,26134731,26181143,26222618,26330408,26374077,26460040,26504956,26538827,26587626,26650959,26685792,26724447,26801972,26846070,26895488,26940428,26991109,27028726,27058326,27103340,27269165,27302114,27382269,27415672,27456315,27489315,27527846,27592492,27635476,27722952,27766235,27860778,27936282,27969228,28004708,28037669,28111402,28162216,28314257,28394625,28431981,28466412,28503699,28545300,28577554,28611888,28772792,28824947,28914255,28958955,29001721,29046198,29087598,29126720,29160578,29234459,29271911,29320342,29368854,29463968,29515205,29557668,29602213,29643788,29680606,29730124,29776536,29810676,29856755,29896391,30021891,30058398,30099093,30140676,30181404,30231283,30274920,30313336,30359674,30409304,30455802,30495038,30525943,30553913,30586435,30622662,30662834,30738060,30782504,30826495,30872377,30911572,30951853,30982367,31019747,31059171,31191944,31248916,31288052,31322069,31364838,31407137,31456247,31493856,31538544,31576684,31616425,31656881,31691095,31740361,31784140,31830919,31890396,32014953,32065787,32097851,32147537,32190990,32235008,32280416,32371707,32423327,32463165,32505503,32548039,32632660,32684751,32727903,32769635,32813741,32864646,32899902,32913999,32927610,32969027,33004788,33062542,33110361,33215969,33261602,33366427,33410855,33458406,33496848,33532366,33561295,33629446,33675791,33716982,33752591,33795134,33845720,33887492,33934391,33992090,34042666,34099079,34157636,34200245,34236772,34274218,34317185,34348809,34381910,34468480,34508033,34558831,34646815,34692209,34738795,34816212,34856718,34901884,34939503,34979728,35027248,35120087,35216165,35270709,35315593,35366574,35450595,35505083,35571017,35630136,35698616,35754590,35823310,35943484,35996253,36110806,36154966,36197612,36246512,36281827,36317077,36345816,36394668,36440701,36480336,36520147,36566906,36665573,36702338,36751850,36798953,36880585,36936759,36975243,37025989,37075762,37125916,37178768,37278176,37328128,37380938,37431199,37525174,37581464,37645455,37689263,37739406,37786711,37830766,37879168,37916249,37961872,38007055,38039642,38068957,38109561,38199941,38241660,38291866,38330047,38410161,38453895,38533930,38612492,38656945,38700931,38748633,38791131,38820352,38898167,38937088,38984476,39032000,39081413,39127788,39167980,39213468,39256596,39303495,39353032,39408062,39448344,39656887,39690971,39730633,39767994,39805029,39842089,39874965,39922323,39961709,39998287,40081843,40119410,40147517,40202851,40242097,40291415,40350227,40396798,40491250,40536465,40628997,40717263,40802398,40838796,40878545,40917459,40996190,41035684,41073881,41126025,41174534,41225235,41268594,41318085,41462841,41506466,41553348,41600167,41765406,41811779,41849731,41944983,41991831,42041033,42083135,42124516,42163740,42215352,42266032,42316306,42362862,42419099,42522758,42574874,42622679,42674830,42720204,42763533,42797035,42838655,42892904,42935261,42967546,43052896,43098125,43149506,43224655,43262537,43344948,43388485,43424711,43501484,43581524,43620516,43665515,43705148,43751034,43859324,43897379,43946775,43990157,44035001,44075459,44133908,44172662,44215020,44300256,44343428,44397430,44437811,44480506,44515552,44559055,44612872,44652494,44761295,44813700,44855197,44888006,44935493,44986552,45029323,45082893,45129347,45187707,45238038,45293338,45337136,45376200,45511520,45584759,45636577,45681978,45734726,45891851,45921679,45956360,46044644,46119030,46166868,46226015,46327572,46367775,46400476,46435920,46472549,46566988,46619773,46656669,46699013,46736396,46826766,46862361,46905723,46945049,46996504,47039094,47080466,47162796,47211052,47247707,47291716,47338097,47390877,47433355,47471478,47514850,47558781,47602897,47690048,47735825,47831202,47869638,47969175,48005501,48046119,48175887,48211662,48252854,48285976,48323809,48369711,48469012,48547570,48586299,48636525,48685006,48720333,48818305,48868535,48914792,48962054,49016063,49066674,49107425,49154467,49197787,49295123,49337861,49382426,49426598,49567908,49640443,49711843,49785484,49848906,49945307,49987145,50076202,50111622,50209294,50255962,50296989,50427599,50470431,50528229,50582843,50692590,50741445,50797526,50851592,50898800,51058387,51155683,51252566,51301394,51381011,51433191,51479414,51542442,51594543,51681940,51721678,51761574,51867622,51912203,51971242,52021869,52153257,52236603,52319518,52362996,52414687,52455098,52502563,52547755,52609532,52727591,52791629,52891133,52947105,53000009,53049486,53160163,53202595,53298859,53341816,53390101,53440053,53485981,53523952,53566242,53612434,53705786,53757540,53806797,53866781,53966061,54067896,54119246,54168996,54219131,54276977,54334196,54385284,54441296,54497718,54595658,54651228,54696063,54757635,54877563,54923914,54975102,55054490,55094249,55135840,55196753,55248501,55301472,55360132,55473384,55530069,55581358,55666069,55759392,55809197,55849582,55896708,55939569,55992811,56038936,56085882,56172659,56280455,56327207,56427430,56476008,56533891,56680157,56725156,56779911,56832979,56902947,56967393,57034533,57079448,57128308,57190630,57261218,57330052,57534611,57632889,57685815,57780999,57845254,57957272,58005833,58143580,58274455,58328327,58376815,58483670,58532905,58571807,58622647,58668703,58835218,58885383,58955464,59093790,59139676,59187129,59237476,59289153,59325806,59360422,59400290,59444967,59480926,59648470,59697803,59750997,59791948,59832484,59881008,59974878,60056130,60109081,60157813,60187212,60230871,60390927,60524282,60592311,60771604,60812602,60861292,60905700,60954144,61011179,61071266,61180503,61225897,61259559,61294705,61332423,61376390,61419196,61463118,61506476,61551470,61636306,61677368,61804729,61840482,61889046,61939303,61984587,62031729,62075557,62104107,62150450,62199340,62244183,62393249,62442343,62480551,62526359,62573021,62731664,62772366,62802623,62846761,62892675,62932680,62977341,63030431,63083359,63138985,63245011,63292732,63344024,63385658,63484635,63534835,63572309,63604975,63611092,63622853,63634175,63639025,63644124,63661371,63714924,63770141,63818631,63863703,63911705,63961717,63998168,64025885,64049303,64077521,64119590,64158363,64197887,64284282,64356756,64413036,64444509,64482819,64523089,64563758,64605916,64651366,64739154,64777701,64820650,64862586,64909625,64953424,65038507,65143939,65236787,65292434,65342139,65462147,65516033,65555125,65723390,65800165,65863361,65912379,65977600,66025708,66075778,66127077,66176167,66223180,66278609,66378974,66427848,66468820,66617693,66737034,66777681,66825433,66869995,66925047,66980947,67032858,67082570,67128532,67173847,67223867,67271280,67321135,67358451,67402491,67508679,67610783,67666916,67824850,67868270,67954982,68001758,68047452,68135579,68179729,68218089,68267161,68366501,68420799,68473380,68527206,68581301,68638406,68694772,68748547,68855597,68903031,68953533,69076300,69119297,69203562,69341739,69380305,69418104,69459743,69534372,69569832,69600749,69643809,69683083,69771418,69809317,69840675,69944677,69995681,70081733,70127561,70183568,70230197,70274559,70352372,70388712,70421550,70457837,70502525,70533806,70568207,70599951,70675528,70713518,70748801,70833823,70875970,70906939,70941912,70982421,71017102,71058062,71110278,71154890,71198778,71241579,71282762,71320324,71390390,71446294,71502600,71579773,71621384,71660364,71699578,71746210,71842213,71920710,71975469,72026596,72084645,72156766,72228600,72283003,72375962,72473777,72510750,72594157,72634327,72674650,72714857,72789517,72827364,72911300,72999431,73044276,73178867,73224299,73266266,73313488,73411303,73514621,73564037,73609853,73649933,73722831,73859865,73907172,73986136,74026583,74077775,74128308,74330957,74376208,74457132,74502730,74542950,74585189,74638518,74677393,74725445,74761465,74810351,74935050,74975457,75055509,75144479,75261344,75302353,75399011,75450088,75496950,75540040,75577697,75632165,75701424,75750335,75798764,75923535,75963013,76000757,76050768,76093201,76132912,76177829,76222087,76267691,76319002,76413227,76455735,76494537,76528888,76615764,76650257,76685725,76717067,76758214,76800892,76882905,76917122,77140693,77187529,77231991,77320697,77360303,77407394,77450233,77497737,77544216,77639591,77704681,77767531,77834840,77938600,78024056,78070634,78127640,78177082,78279102,78331719,78430162,78477314,78521139,78571057,78616189,78662172,78700592,78726734,78761493,78805707,78849805,78903695,78951879,79032342,79077403,79128322,79169636,79219523,79257499,79332669,79377051,79422508,79454504,79506274,79556559,79601472,79730064,79774907,79857877,79877006,79985144,80086451,80204450,80262925,80319409,80382074,80443513,80496146,80556968,80613715,80656070,80707683,80754500,80847922,80890255,80986017,81030840,81070520,81122121,81158395,81245951,81294744,81389119,81434730,81481967,81537212,81589248,81638487,81693524,81846684,81908985,81963516,82014611,82060794,82096733,82187978,82238683,82292285,82377301,82414346,82448146,82493455,82537688,82640238,82862286,82923514,83031817,83083413,83142186,83202260,83253110,83339740,83384668,83422353,83468442,83512514,83594788,83687348,83763359,83812746,83904835,84005216,84047727,84098606,84141053,84189352,84243103,84284757,84327515,84391720,84456203,84586620,84633265,84685977,84792043,84842126,84982430,85025481,85096245,85183573,85230926,85367194,85410273,85494540,85560034,85592036,85627308,85710908,85744461,85827120,85854617,85917628,85950556,86054394,86115084,86227473,86266881,86308212,86337392,86411447,86459559,86496997,86582532,86623337,86664453,86696992,86736910,86964107,87059469,87106421,87146944,87182693,87264407,87322036,87425723,87484590,87533452,87588299,87634118,87691267,87825637,87863220,88026909,88066982,88107756,88162943,88217844,88279240,88386487,88447309,88505367,88563474,88610827,88661091,88710352,88782230,88842501,88902269,88955312,89000867,89046404,89086348,89127135,89217263,89257228,89294467,89344398,89395701,89448617,89502138,89563953,89611873,89758629,89804495,89847491,89943697,89982963,90028890,90077356,90111187,90149425,90268792,90312830,90383273,90422173,90462287,90502146,90627052,90658160,90696821,90729280,90761342,90803734,90843116,90882737,91011340,91057079,91099509,91146824,91242175,91304488,91362628,91414326,91460829,91503015,91586419,91632773,91681177,91722776,91798250,91837362,91886606,91934244,92024136,92119554,92155746,92199761,92240336,92277818,92312747,92362915,92411469,92456171,92511042,92573180,92623924,92670400,92713924,92768701,92810743,92848794,92936737,92974297,93012016,93050800,93139901,93245226,93286376,93323533,93440477,93503011,93553890,93599370,93637307,93717108,93753682,93849820,93924636,93973392,94016214,94093646,94171089,94284858,94331051,94387387,94430412,94469004,94514199,94563143,94607880,94702074,94792254,94833122,94934690,94977574,95023770,95116278,95151767,95188818,95238521,95290212,95335460,95415932,95453922,95499563,95542473,95574507,95647008,95714377,95750678,95792195,95831206,95864697,95891416,95950556,95980024,96006113,96078678,96123301,96155751,96193226,96249554,96295658,96354698,96411220,96465295,96585565,96648742,96714109,96764751,96805333,96855782,96911124,96966559,97015858,97060964,97111388,97156094,97222407,97342380,97407610,97465737,97514753,97563357,97609636,97657273,97700865,97751747,97849230,97947760,97993064,98170196,98265967,98309419,98352491,98397571,98444320,98484984,98523034,98568328,98614950,98665486,98736514,98762860,98803883,98841223,98882927,98920705,98951896,98982190,99083715,99112422,99148712,99225971,99299746,99331205,99368622,99410917,99434140,99474303,99574123,99613714,99702241,99746890,99777668,99824209,99874153,99925829,100098308,100166795,100280875,100407985,100453400,100494104,100533896,100571075,100663883,100705354,100744625,100792178,100840058,100898541,100957461,101079007,101122380,101162069,101209882,101262768,101306776,101353164,101401159,101443922,101482240,101558557,101666500,101708310,101743994,101786000,101824491,101864378,101910423,101993515,102029644,102064962,102135145,102182710,102271046,102314669,102361444,102410036,102491933,102589451,102620510,102663507,102702114,102785185,102923992,103023283,103078680,103121045,103165891,103215943,103250613,103295287,103335790,103370704,103408192,103448598,103488492,103568587,103605615,103642530,103683651,103719972,103774428,103825892,103864951,103901939,103938828,103994168,104039195,104077060,104114750,104150988,104190577,104264029,104294789,104331884,104369044,104406867,104459761,104594624,104631505,104670075,104708382,104740540,104773074,104809749,104856865,104891092,104938803,104979086,105055177,105090850,105127442,105192432,105275801,105354915,105388837,105417781,105456574,105495140,105540707,105639154,105714154,105739700,105781088,105813735,105854360,105900387,105942822,105985712,106026941,106070195,106115104,106181302,106217881,106285738,106326780,106369083,106446543,106512194,106589400,106625940,106652204,106682022,106721400,106760896,106808803,106852462,106941318,107037416,107073437,107108006,107146376,107193722,107240259,107288535,107334983,107385731,107448116,107521043,107570782,107623207,107710137,107752217,107803333,107884363,107918819,108003452,108131089,108170892,108213837,108255161,108291301,108330152,108366620,108409763,108562441,108609111,108655033,108690126,108728627,108758051,108797995,108843900,108889127,108935569,108981695,109028362,109066731,109104539,109141574,109223200,109259064,109334999,109372390,109437052,109471883,109505140,109540684,109576925,109618559,109700930,109729987,109813010,109854861,109889221,109927086,110000596,110039021,110077751,110120665,110198930,110237853,110277422,110314769,110376855,110447328,110493015,110525841,110560745,110597298,110639585,110675616,110716802,110760505,110802534,110838703,110871243,110933267,110966096,111004145,111038379,111073076,111104385,111129053,111150024,111177434,111202064,111236766,111269277,111302424,111330368,111370615,111420998,111459104,111495176,111533874,111575914,111620931,111661710,111695934,111728767,111761068,111807859,111858911,111905979,111950692,111978995,112009831,112038273,112066812,112095246,112128232,112160860,112193040,112220547,112248013,112283058,112313712,112526399,112558019,112592004,112617208,112662652,112691474,112806296,112839317,112907759,113008064,113044780,113082171,113108685,113151299,113198563,113244418,113285909,113318840,113354375,113388046,113418574,113441991,113471811,113500484,113527319,113561806,113630385,113664067,113686197,113716509,113746250,113774092,113812897,113847762,113889228,113933651,113973270,114000425,114022946,114051002,114079018,114101311,114136405,114166154,114195692,114221765,114262351,114294059,114457899,114497396,114523062,114544536,114579004,114616923,114752791,114774439,114823936,114848968,114942160,114979319,115011854,115048168,115087313, respectively;
The position of the SNP locus on chromosome 14 comprises: 19004241,19014220,19026535,19040054,19048893,19080173,19109812,19265588,19435427,19484909,19744897,19820800,20113335,20207317,20245067,20280927,20318112,20378549,20411078,20486786,20520675,20590513,20638141,20672763,20711469,20758366,20805662,20839307,20881138,20919319,20957923,20993439,21032595,21074683,21107126,21181461,21212108,21241596,21311645,21349932,21401495,21477616,21515528,21552835,21597014,21631457,21680716,21727988,21773480,21813156,21860866,21968504,22012216,22077177,22108653,22144071,22188829,22233399,22310189,22411486,22440258,22476144,22516578,22545241,22586343,22616049,22652274,22718330,22751334,22786996,22835396,22880443,22926919,22970035,22995074,23074899,23113817,23210109,23242980,23305751,23345287,23391086,23436369,23493504,23543881,23660058,23735900,23791520,23845461,23882350,23905751,23948928,23999814,24109696,24154702,24184084,24220391,24252018,24291771,24338431,24382212,24421676,24461507,24513520,24714264,24754046,24800577,24839897,24888697,24954202,24995331,25052827,25149580,25243751,25285846,25345898,25390661,25431699,25482474,25537228,25577942,25620327,25659076,25736541,25769922,25803217,25849033,25887349,25923648,25973239,26016909,26066679,26107494,26147126,26188556,26237458,26294886,26356384,26476094,26520201,26558679,26599561,26703176,26752004,26793599,26829859,26873787,26927111,26992064,27051340,27163828,27205328,27315523,27376505,27440457,27541667,27624981,27731432,27822638,27867818,27915411,27973832,28066265,28118949,28167755,28259669,28297700,28320904,28366190,28416025,28459002,28504321,28547260,28593927,28636781,28689161,28739646,28840617,28880796,28930035,28983650,29022242,29061653,29098755,29147346,29192618,29303677,29430305,29541494,29655520,29719646,29772059,29836773,29900195,29956060,30003024,30085236,30118463,30162013,30215086,30326858,30375428,30425562,30534152,30583474,30633717,30683130,30741045,30803862,30854448,30911690,30972850,31023554,31073297,31120787,31179594,31268748,31309814,31353247,31397476,31486706,31528062,31585174,31631771,31685061,31729807,31773068,31822149,31872749,31914971,31959641,32004528,32052978,32104842,32193674,32232732,32276011,32310250,32352633,32396952,32426604,32520038,32590304,32651796,32765622,32812511,32848218,32893342,32967586,33013596,33063524,33111792,33162621,33207400,33248858,33289463,33325196,33412626,33453647,33496978,33548252,33590891,33633155,33679447,33729340,33777735,33814021,33850155,33898971,33942623,33990830,34075510,34125226,34165057,34210238,34257510,34306451,34347610,34393602,34433221,34468721,34506408,34548054,34592274,34642612,34718605,34802241,34876199,34917022,34952887,34989817,35044556,35092927,35135607,35176730,35210156,35256361,35302350,35342838,35385655,35424436,35570816,35618360,35658638,35709009,35760054,35801346,35871444,36045942,36117545,36186182,36247283,36306407,36367009,36417777,36454580,36500842,36545461,36584219,36680746,36727174,36783877,36841159,36891135,36945392,37001352,37045498,37091499,37132248,37223166,37263178,37307414,37394567,37441176,37487132,37575793,37617232,37665045,37779265,37829448,37885731,37948621,38006519,38061336,38121370,38174634,38212551,38269967,38318172,38376573,38488659,38544470,38591024,38678056,38736784,38782096,38863987,38947357,38994672,39043263,39087408,39136292,39187312,39242720,39300780,39351589,39405310,39452687,39554078,39635469,39667661,39758196,39792555,39886855,39991127,40046317,40155469,40196876,40252768,40306839,40350587,40402365,40447058,40503709,40550580,40587407,40677483,40788882,40843130,40884074,40919556,40954725,40989521,41019126,41049211,41076770,41112714,41157196,41205566,41255667,41303944,41338165,41430022,41474756,41506225,41527131,41568836,41602337,41678659,41727607,41771455,41819091,41873129,41917702,42029085,42092402,42153162,42198410,42320790,42422532,42472305,42509986,42547285,42589387,42631920,42679654,42719876,42758259,42800019,42872292,42914536,42957137,43048131,43093153,43135501,43188383,43233288,43279961,43330160,43379414,43422101,43464405,43501589,43540246,43574709,43615856,43664043,43723085,43776163,43823570,43868549,43912336,43957047,44003136,44053466,44096772,44140830,44192700,44242704,44339448,44402502,44444697,44491754,44536876,44581257,44629572,44669124,44725022,44770916,44821980,44879327,44961819,45001676,45042709,45051733,45094980,45145699,45191205,45245255,45307793,45364920,45416026,45480376,45540960,45612664,45675772,45741270,45816340,45889010,45961699,46065940,46125095,46178308,46230859,46275487,46322950,46352072,46389898,46432793,46475174,46516539,46606306,46653857,46697082,46742642,46791230,46837024,46888821,46934687,46975411,47022731,47080771,47128019,47218924,47266095,47323422,47388474,47431531,47478505,47567007,47612161,47725989,47768412,47808059,47854101,47898038,47945667,48006771,48064755,48117246,48242149,48284452,48355496,48398664,48439631,48489272,48568453,48642419,48701173,48750194,48843135,48900342,49021398,49075229,49169314,49228155,49281568,49370571,49464841,49513651,49562370,49648421,49699543,49748071,49789020,49925776,49973195,50022044,50105684,50151115,50212718,50262257,50310018,50357061,50438798,50478492,50560177,50640128,50765502,50800588,50846269,50895137,50997546,51058234,51107737,51185923,51228655,51278057,51318288,51354682,51391006,51431223,51509390,51549634,51595335,51638966,51689905,51739293,51784942,51910661,51956718,51997580,52044247,52082661,52129311,52180569,52222161,52270982,52350131,52395480,52428759,52472795,52501902,52529083,52570890,52614501,52645705,52675539,52756594,52798092,52838084,52883981,52938919,52992462,53037128,53151341,53209963,53413208,53551106,53613974,53663595,53704749,53754559,53797644,53827368,53881839,53933920,53984191,54043150,54102009,54153107,54194185,54240454,54299289,54392613,54441614,54491149,54547435,54592962,54646469,54689343,54754604,54804507,54843017,54884511,54936346,54994826,55053210,55094425,55143117,55185030,55268294,55316232,55367416,55405427,55454956,55507628,55561232,55726425,55769883,55810831,55849213,55895104,55923210,55956526,56038180,56088860,56136040,56181300,56221819,56307085,56348839,56387545,56426945,56474458,56518856,56557345,56603088,56660107,56696472,56743073,56871878,56927344,56963182,56997940,57073932,57119945,57162880,57207836,57342832,57381105,57427625,57473275,57555827,57708608,57771773,57829026,57886005,57938118,57980417,58022794,58107933,58144371,58226607,58275992,58323765,58363425,58433026,58517384,58566228,58685833,58741618,58795687,58931528,59060102,59112475,59157919,59241220,59282645,59325631,59366252,59422619,59460548,59501704,59543107,59582631,59624317,59678626,59777688,59827386,59863176,59907789,59956113,59995842,60045199,60093819,60165473,60269379,60328427,60402519,60464145,60520579,60675060,60779031,60842391,60917496,61031284,61085141,61138847,61182085,61254110,61321331,61384863,61450658,61575640,61616263,61654643,61693613,61731920,61835400,61879332,61919216,62064257,62112982,62299007,62350814,62397867,62459095,62502340,62539699,62677341,62758340,62803697,62888268,62919811,62989803,63034299,63079703,63105687,63147993,63199660,63248290,63343862,63493537,63542044,63598207,63642791,63743564,63783052,63825672,63863816,63909290,63945101,63982105,64067436,64109428,64164425,64214837,64266131,64312318,64355806,64403654,64497929,64541600,64587401,64687710,64724993,64780116,64832600,65030190,65089468,65135586,65182316,65232095,65268451,65307246,65352423,65437562,65491804,65549089,65599443,65635440,65720143,65762051,65847351,65896041,65991737,66049184,66100768,66152004,66205649,66253437,66296087,66339725,66388000,66431896,66475442,66517776,66563491,66675364,66729277,66788116,66846217,66909881,66957196,67013165,67058902,67059238,67106634,67150673,67206082,67257994,67311322,67373863,67431696,67495340,67541422,67601861,67656917,67708717,67758504,67805014,67855598,67905423,67987253,68035175,68073358,68115459,68161356,68206891,68248774,68298812,68353879,68407385,68464273,68592542,68641096,68705020,68754824,68799303,68895693,68941989,69039588,69074606,69118241,69158040,69198917,69232191,69275310,69390185,69432044,69476895,69521338,69575941,69635175,69687045,69778816,69822927,69866847,69924302,69971627,70026853,70084011,70136653,70188636,70233186,70276933,70319261,70362890,70401755,70442987,70488431,70579715,70615594,70650834,70693175,70732443,70813520,70857022,70897737,70940591,70990385,71043556,71085059,71169310,71212158,71253992,71330918,71373580,71422789,71469015,71525765,71586319,71628063,71663816,71707781,71829782,71892566,71963428,72032351,72109945,72185653,72245203,72293012,72334597,72376451,72421334,72465383,72496823,72582474,72630071,72705363,72738833,72778834,72816180,72906389,72950438,73027000,73064446,73109766,73158413,73205950,73282419,73318473,73356299,73392938,73429916,73466280,73556416,73602899,73649732,73728386,73770312,73824215,73867487,73908201,74005488,74050321,74087595,74131122,74168431,74216606,74299507,74373609,74416646,74533691,74574163,74615378,74651913,74691932,74726009,74756776,74793881,74841467,74886168,74931153,74982212,75075785,75182315,75241606,75307588,75356799,75450199,75546250,75603239,75654933,75750466,75871657,75917207,75957952,76038388,76087014,76139134,76258581,76321510,76372254,76429157,76475949,76523191,76570684,76613678,76656460,76741336,76815889,76858983,76899467,76932061,76973328,77006765,77083749,77126240,77151803,77186640,77229532,77281882,77354554,77397668,77440625,77480599,77553906,77597268,77637976,77697637,77738918,77788749,77833808,77880104,77925154,77958858,78055036,78089870,78162617,78203650,78244635,78282771,78356245,78401921,78534475,78571385,78612850,78698154,78739383,78825609,78874209,78919999,78962030,79004001,79059667,79105473,79252797,79296488,79356051,79449663,79490575,79570322,79621431,79660882,79711725,79761736,79827037,79877592,79935212,79980316,80024861,80068984,80108238,80157170,80203080,80301514,80390370,80474190,80533865,80584555,80639349,80694103,80770565,80837785,80884583,80936298,81039132,81092103,81127849,81174506,81226088,81280664,81330921,81373372,81416915,81546732,81586470,81696252,8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The positions of the SNP loci on chromosome 15 include: 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The positions of the SNP loci on chromosome 16 include: 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respectively;
The position of the SNP locus on chromosome 17 comprises: 67859,85376,103775,131064,154378,196014,213975,239479,275604,409155,441590,481187,521423,550621,578180,653339,687843,713341,736927,762451,792999,837680,864462,926315,951644,968807,1004949,1080472,1116410,1142734,1175622,1197782,1224442,1287782,1327909,1396168,1441378,1487488,1522310,1564328,1606435,1647782,1687341,1721157,1754894,1791217,1829252,1944707,1995612,2045273,2093511,2146355,2256513,2290345,2431515,2467204,2521780,2571891,2619698,2659588,2698296,2732896,2773639,2808508,2846365,2917277,3009216,3056544,3104252,3143155,3192409,3222813,3270509,3347952,3422770,3451154,3549470,3615306,3647744,3686982,3728538,3804721,3876433,3956245,3993633,4032167,4106828,4151859,4238152,4291406,4320515,4347702,4377687,4410659,4479159,4551967,4579301,4612249,4686238,4728348,4776655,4869363,4923984,5036740,5141317,5208990,5259656,5297293,5386996,5418660,5450573,5491874,5536715,5660131,5696158,5727675,5762730,5796006,5832753,5863420,5903291,5941868,5982751,6024552,6053549,6091502,6163894,6233223,6277786,6308276,6335844,6366723,6451343,6487497,6535552,6579053,6736935,6843229,6887277,6933638,6967603,7003446,7036354,7077856,7122960,7175269,7217484,7269875,7314435,7362514,7407652,7440984,7479939,7570823,7592412,7636497,7737596,7795832,7849752,7903749,7949434,7986438,8019299,8057572,8243469,8282512,8376954,8470906,8515070,8565937,8609637,8639304,8680314,8789674,8837592,8879910,8923868,8968167,9007824,9086215,9148464,9192895,9234397,9271614,9308611,9384926,9453015,9495392,9541444,9582692,9722150,9755184,9788638,9821400,9888172,9923330,9960805,9996891,10027383,10060500,10125737,10160475,10209661,10302990,10366693,10429261,10474369,10518835,10559868,10599089,10680890,10727677,10764777,10802811,10839109,10917695,10958741,11006970,11053946,11098386,11140892,11182840,11221011,11255602,11298829,11380684,11422446,11461506,11541770,11592928,11632987,11674928,11719552,11759364,11807001,11849285,11893372,11949989,11993876,12043389,12082516,12118496,12164916,12228533,12267219,12343501,12380955,12422308,12462543,12593541,12730917,12767403,12804048,12843555,12876471,12907023,12941953,12973649,13009228,13042365,13084351,13152867,13188333,13227516,13272104,13317978,13358465,13397956,13436579,13468731,13565011,13665400,13783915,13812283,13849340,13892591,13928401,13971982,14020950,14075583,14120776,14167742,14206135,14243542,14282555,14316976,14347431,14376648,14409988,14444117,14477601,14514409,14545523,14574378,14609875,14647771,14680932,14716408,14843663,14881087,14912257,14986973,15026129,15065116,15100053,15146512,15190185,15320898,15359583,15397661,15439334,15549485,15594316,15649490,15694743,15747683,15799743,15847865,15886096,15932130,15986128,16072279,16108288,16208719,16256671,16302806,16344945,16381433,16428657,16538144,16587975,16671587,16733874,16778904,16811940,16847909,16883680,16976800,17032248,17081322,17121700,17167986,17210709,17255437,17298412,17338020,17385701,17426352,17470609,17554652,17611411,17671896,17720391,17822480,17880209,17938784,17990671,18042312,18143254,18192954,18244031,18391153,18514057,18584212,18649366,18714812,18823705,18869330,18920619,19182201,19234205,19295467,19355797,19416037,19461517,19506290,19559529,19602637,19644411,19684364,19732233,19833772,19885584,19933625,19977614,20025022,20086402,20140785,20198024,20260186,20383057,20472753,20584700,20634859,20678002,20721362,20770238,20781085,20811017,20860716,20931020,20972331,21078778,21123845,21168954,21199650,21210252,21219857,21228981,21236657,21253054,21297686,21311771,21320425,21329929,21340156,21351431,21449539,21508593,21528545,21539344,21548956,21555430,21563348,21679794,21723834,21825882,21877857,21910903,21964842,22020219,22121692,22180142,22211547,22232055,22254627,22259230,25265441,25273494,25280134,25286747,25292701,25300052,25307371,25319863,25333491,25376198,25416627,25472795,25517316,25574158,25691319,25733374,25781065,25837690,25900035,25959421,26047713,26085969,26127612,26185418,26245329,26304121,26500298,26569174,26686339,26779795,26827773,26874859,26960896,27085839,27202160,27268937,27329280,27371788,27418161,27465664,27523019,27572412,27624724,27737821,27792855,27902205,27968973,28037506,28092376,28159344,28304334,28381883,28443334,28501530,28544346,28592567,28648643,28701327,28761735,28822666,28922790,28974134,29024318,29057710,29093958,29126324,29177441,29230537,29340171,29401044,29455520,29561462,29662317,29710763,29754641,29797381,29833878,29918817,29961095,30000270,30034299,30068383,30159884,30212931,30263751,30350802,30413626,30464222,30515522,30556500,30602094,30643016,30696346,30828167,30871418,30906133,30951804,31004123,31062733,31186791,31241311,31324295,31357952,31406648,31457902,31501900,31549309,31596781,31639502,31691667,31737580,31776806,31813439,31862275,31905238,31943851,31984300,32022601,32069228,32112868,32155632,32189975,32230085,32275870,32356921,32406410,32487282,32530658,32578860,32615798,32672592,32711241,32751306,32785464,32862852,32903817,32990718,33028341,33066048,33119730,33173469,33241967,33307591,33417971,33468289,33512335,33559987,33607396,33699772,33748837,33782520,33825907,33876202,33917322,33963878,34007719,34060127,34116228,34164603,34268126,34301451,34338758,34378370,34415356,34444443,34474477,34880995,34935670,34986187,35022240,35064768,35143611,35176533,35246689,35329480,35430767,35481477,35593801,35657339,35861600,35909455,35969536,36026807,36065702,36109164,36156125,36193288,36228819,36307980,36399132,36504459,36598626,36698780,36757596,36801837,36849973,36994904,37035719,37075758,37125106,37178429,37221164,37259455,37295052,37365647,37467694,37505887,37557599,37721301,37822416,37870837,37916071,37975214,38028266,38077377,38118752,38249909,38366381,38430592,38494150,38561178,38613809,38662803,38703924,38765380,38816046,38904247,38946965,38986961,39027213,39063788,39100006,39142330,39225785,39265865,39336167,39418252,39458322,39502409,39549162,39594539,39625526,39662169,39705380,39742985,39785042,39829422,39868825,39904681,39941230,39988601,40034172,40089319,40151750,40211546,40266716,40316835,40375425,40439229,40483537,40530376,40569974,40624902,40688809,40739171,40788148,40842689,40907581,40957703,41008752,41063093,41110720,41151947,41197731,41220288,41243581,41252575,41278725,41332900,41387610,41436652,41466108,41546587,41598317,41650012,41698748,41784302,41832148,41882700,41939438,41978635,42017968,42054614,42096980,42141744,42191810,42245347,42329542,42339407,42339999,42373961,42421862,42466043,42574576,42634234,42670660,42711420,42770479,42820385,42876865,42925752,42973517,43017902,43062848,43153389,43252536,43306084,43358566,43405992,43454442,43526947,43578784,43656591,43668226,43704082,43764847,43786236,43807899,43832337,43852605,43890215,43920913,43940825,43964741,44033468,44057181,44081527,44149741,44172327,44196015,44216664,44257783,44277265,44296937,44332970,44345114,44355778,44806862,44869232,44915412,44962046,45056928,45095678,45150655,45195233,45216210,45252379,45291101,45368248,45410386,45466285,45574733,45660388,45717955,45770414,45828235,45870638,45962550,46016084,46065046,46115702,46202514,46252333,46307835,46429444,46538790,46583772,46623054,46675770,46724432,46771369,46818553,46865334,46914755,46964812,47007497,47041601,47090851,47148172,47196790,47235621,47280915,47378766,47426866,47474571,47522145,47563873,47607058,47657098,47724632,47784199,47865604,47979143,48026281,48069009,48102637,48236825,48278549,48323192,48369381,48448035,48490600,48595988,48634553,48683200,48735837,48786462,48830002,48871331,48906801,48957792,49006364,49057267,49114413,49175864,49272257,49367822,49423863,49466523,49499797,49602053,49713772,49749141,49792230,49833866,49880942,49928833,49973249,50017470,50122130,50172676,50236186,50288081,50333958,50372664,50431479,50492438,50653250,50702693,50748782,50791882,50830843,50866238,50943687,50983863,51024305,51077504,51119434,51163545,51209417,51257006,51309790,51399277,51458544,51505435,51598185,51649766,51698866,51795110,51842274,51909966,52019278,52071378,52116729,52166913,52226238,52277081,52334981,52392314,52449912,52506670,52567832,52662935,52695967,52746066,52788660,52838491,52927879,53006654,53049330,53099936,53156810,53301142,53349194,53403565,53445858,53491455,53536867,53585113,53624040,53712589,53758266,53805664,53851237,53896995,53943244,53990908,54034555,54079013,54167267,54381160,54434804,54597745,54641678,54692306,54736372,54775945,54818658,54863210,54906239,54950633,55047615,55095409,55128625,55170834,55208789,55252189,55395557,55440310,55490021,55578149,55618420,55666758,55712238,55760001,55803083,55839278,55876106,55912974,56004757,56066168,56127347,56237810,56277106,56371624,56424185,56493667,56559485,56628915,56683204,56731265,56778271,56839579,56970823,57114769,57250049,57366430,57473166,57523482,57580903,57644265,57777722,57840841,57899687,58004461,58083750,58159784,58221701,58276610,58331208,58392390,58514240,58558658,58601922,58659331,58726771,58786869,58836032,58883651,59010131,59075568,59151946,59224589,59272908,59323043,59371657,59420632,59467908,59511464,59616204,59654453,59761470,59819943,59939018,60057501,60111915,60166759,60207612,60261166,60305765,60358435,60405907,60452799,60508341,60564331,60613846,60677604,60785641,60833833,60883269,60923236,60971749,61024746,61085984,61225605,61297951,61367302,61438714,61517569,61610223,61728063,61787161,61834996,61878317,61927774,61962769,61994968,62022968,62069095,62109315,62155031,62207097,62258828,62306449,62365464,62407380,62505812,62570152,62631069,62721475,62781409,62862921,62977919,63101778,63133071,63208588,63241074,63274263,63315851,63356702,63398040,63439951,63480944,63606208,63647769,63695074,63794637,63858636,63911073,63948693,63973698,64006593,64034478,64066101,64182376,64255926,64285489,64328709,64376069,64412541,64455954,64493956,64536487,64575027,64618971,64660848,64707461,64742272,64787911,64860340,64900825,64944778,64983533,65018284,65115703,65175993,65241398,65288927,65390645,65443089,65489541,65572090,65617668,65654534,65697286,65730404,65862989,65913018,65963947,66012156,66085308,66147296,66180074,66210828,66277401,66326553,66418070,66460604,66502320,66591980,66635610,66714875,66800200,66838520,66893462,66937575,67015279,67069025,67129667,67182688,67232145,67289544,67339779,67386495,67487387,67525322,67572382,67617141,67684476,67856232,67902689,67985947,68041438,68079712,68111227,68154997,68202121,68283969,68320097,68358736,68411577,68536705,68586154,68630337,68676243,68812382,68858685,68930717,68972917,69058994,69095028,69134485,69214718,69338875,69421960,69462277,69501896,69591787,69640764,69687431,69733693,69776449,69825129,69873469,69917056,69955942,70003923,70084273,70131780,70173415,70218748,70266250,70313299,70361434,70398761,70438562,70477615,70518582,70558668,70600834,70679800,70717952,70783009,70823979,70915078,70951930,70993409,71076139,71115694,71146429,71182921,71256855,71333086,71372032,71405960,71484445,71524887,71565338,71690747,71719292,71745951,71821620,71858039,71900067,71944085,71983035,72052420,72088284,72117573,72192553,72228208,72263329,72303055,72342411,72383908,72461868,72531509,72563738,72729658,72831038,72876175,72916895,72963649,73052879,73089882,73177650,73217773,73252006,73294294,73333107,73371658,73415826,73511129,73552185,73582568,73616864,73667033,73719910,73760235,73810937,73901749,73951976,73992275,74037715,74086924,74124287,74173374,74220756,74264876,74348744,74390406,74513758,74703582,74794268,74823282,74860395,74928984,74961266,74997307,75033234,75070231,75105006,75150683,75193796,75234203,75259828,75299182,75377700,75409282,75451145,75487649,75523156,75557354,75583599,75619793,75651395,75686193,75720056,75839050,75876626,75913538,75951065,76010997,76065122,76111972,76219611,76255085,76286229,76320491,76426486,76458740,76481613,76509133,76538199,76564642,76597523,76635474,76676748,76729227,76777487,76817361,76861888,76893135,76961613,77009102,77047937,77088895,77128495,77156381,77189989,77224268,77253136,77307717,77335350,77367542,77396011,77466803,77544850,77676335,77710078,77751983,77801283,77875711,77906477,77945111,77997465,78026895,78063964,78090815,78133098,78175854,78206618,78239532,78271645,78315519,78353008,78395114,78431276,78475988,78524244,78602643,78636736,78668496,78737818,78780759,78814307,78850068,78877248,78908820,78940813,78972192,79006089,79037712,79109033,79139725,79178431,79214894,79256648,79300234,79373883,79452768,79480302,79520132,79629781,79667228,79767023,79929849,79986156,80029460,80065225,80126712,80198007,80239484,80281657,80355153,80399892,80441236,80476541,80516173,80546017,80618562,80743080,80779221,80810037,80841147,80874109,80907283,80955518,80983367,81001170,81021121,81059259,81163152, respectively;
The positions of the SNP loci on chromosome 18 include: 59388,95919,111548,204814,252472,299724,405444,435833,472368,511009,549547,582734,617011,651551,680985,714378,751793,833872,865657,899866,937950,988628,1044792,1088272,1130939,1191418,1234174,1280026,1335265,1436914,1505233,1558812,1593106,1629693,1670445,1717543,1756469,1801797,1842908,1891260,1931066,1957529,1982946,2015601,2060317,2099267,2135466,2169279,2210583,2266798,2297986,2332770,2380157,2418085,2460759,2492386,2563154,2606057,2642951,2678279,2712180,2753411,2830672,2901148,2946448,2991515,3024264,3196356,3242575,3277162,3316176,3350073,3384176,3418464,3455984,3490471,3558116,3599424,3629633,3668061,3700771,3750980,3794396,3844986,3975494,4008599,4053614,4083561,4118444,4161572,4202622,4242887,4280712,4316301,4356352,4388537,4421552,4456681,4499657,4548823,4589283,4629348,4673164,4755369,4791068,4830863,4878847,4933592,4972834,5023457,5100124,5147490,5190861,5219865,5286076,5326955,5364916,5409721,5499830,5548672,5594739,5692313,5731251,5779890,5829705,5873630,5924607,5960068,5993859,6036979,6076906,6119790,6157072,6199459,6250983,6294047,6337489,6388977,6434158,6508305,6545875,6583968,6626549,6662252,6704756,6796110,6847940,6890411,6926854,6963828,6999368,7030450,7065323,7100828,7137816,7168468,7204218,7248346,7282531,7331085,7366739,7403687,7436953,7484216,7520914,7580972,7645003,7687679,7737499,7790899,7840035,7885531,7934969,7977410,8024438,8077858,8135572,8179937,8250662,8298871,8371843,8410768,8445152,8507785,8550999,8630286,8667407,8703302,8739460,8820886,8858422,8892362,8927124,8963003,8994831,9032642,9079763,9132371,9230668,9343873,9390655,9430895,9513023,9705201,9744160,9780938,9816271,9857364,9937814,9967164,10010426,10056339,10104747,10143384,10175158,10214581,10251981,10292881,10321853,10353707,10387068,10462636,10499643,10536793,10643952,10679128,10710530,10741946,10784331,10822428,10863771,10913492,10950506,11031166,11071687,11109550,11157240,11199425,11238106,11276769,11320782,11366783,11408342,11449223,11534183,11578528,11616251,11654176,11729029,11769148,11842887,11874548,11905953,11940799,11972116,12002551,12036610,12075431,12111262,12167953,12221985,12255300,12375871,12414499,12459410,12509095,12598459,12640183,12685321,12734851,12771159,12808140,12854340,12884676,12926924,12970275,13015490,13069796,13160516,13251234,13291698,13390244,13471295,13505686,13542861,13578887,13620294,13672407,13701979,13750551,13836334,13871684,13904668,13939569,13983973,14028993,14065037,14160616,14185530,14223336,14259310,14279150,14301153,14349528,14382275,14411607,14463075,14511944,14610280,14665681,14705908,14740746,14780777,14832424,14866373,14908714,14959300,15002003,15052618,15093211,15133057,15167944,15183336,15209106,15256718,15306073,15348421,15379714,15410313,18513345,18538610,18611243,18677089,18824417,18896030,18974408,19039266,19162853,19280800,19344612,19406847,19468635,19572159,19614316,19646740,19682131,19725197,19777745,19820907,19914189,19964645,20010871,20062034,20106717,20160581,20201911,20246323,20294153,20399435,20514272,20567883,20618082,20660330,20699029,20747183,20845537,20940689,20988701,21077207,21114997,21154943,21314315,21379516,21441302,21501766,21558866,21603805,21637216,21679098,21714182,21752172,21792711,21837165,21882812,21926121,21971165,22006244,22053605,22090217,22126080,22163139,22207589,22247642,22321177,22358076,22402449,22443352,22529054,22578908,22626170,22673354,22714608,22763335,22813136,22869369,22956049,23006011,23054210,23099810,23146123,23242346,23303664,23350992,23401898,23444096,23487306,23534044,23573098,23656489,23707994,23760319,23858237,23901737,23955260,24007502,24101749,24191021,24271378,24405040,24442580,24509663,24547138,24591355,24631358,24675748,24723763,24777533,24841163,24904188,24952522,25004159,25057791,25111040,25158553,25204161,25245308,25301535,25362977,25411535,25441209,25481035,25527707,25566317,25612276,25657876,25700435,25741877,25789269,25832357,25873349,25955510,26016830,26129728,26180690,26229642,26270166,26331734,26379410,26476437,26517205,26618583,26669253,26712899,26759910,26817903,26878802,26936161,26982652,27071828,27193345,27234003,27285624,27333762,27379173,27432956,27491494,27535666,27635308,27674072,27717461,27760901,27829579,27875024,27921679,27959676,27998727,28039282,28073338,28111388,28145428,28186594,28297988,28363713,28421734,28479781,28578506,28615354,28654178,28701462,28767024,28909329,28954225,29001571,29037814,29075164,29123759,29205953,29259129,29310401,29362630,29411722,29457886,29502263,29580120,29625535,29672676,29719151,29766033,29807287,29908792,29967006,30027092,30071388,30121169,30163086,30215033,30269631,30314632,30461178,30503160,30572822,30634652,30754960,30810112,30858466,30881667,30947576,31053378,31104359,31162123,31271619,31327318,31374412,31606097,31668079,31732388,31797312,31869974,31930577,31992108,32202495,32259398,32321794,32414465,32465952,32518790,32608804,32656935,32717380,32760753,32828547,32884268,32938869,32989846,33034175,33129076,33179357,33279657,33321683,33367953,33413127,33462063,33517945,33562227,33617415,33665075,33749371,33788441,33831682,33871081,33920558,33967277,34010589,34059157,34099913,34148356,34193419,34229194,34319157,34378445,34443765,34511406,34572968,34640709,34786089,34935496,34982881,35076342,35173468,35224987,35277848,35326624,35371106,35430332,35482042,35533277,35580083,35628804,35673039,35770485,35819409,35862642,35959232,35998453,36037061,36071951,36118149,36156774,36203841,36250517,36306999,36372225,36426522,36577642,36632661,36692045,36751860,36815582,36925486,36971454,37021457,37082773,37218846,37270472,37335340,37395546,37513230,37571008,37619957,37719317,37777080,37829879,37875781,37957018,37999500,38083812,38136815,38264488,38304682,38353385,38400722,38479732,38621118,38665265,38714499,38765007,38861555,38944999,38989153,39036005,39083827,39131943,39172387,39217734,39265215,39317914,39435052,39471367,39524695,39567322,39625623,39715794,39769815,39823559,39864712,39909507,39952103,39999601,40048135,40151027,40188988,40230147,40274813,40323522,40378436,40437051,40487283,40548565,40602733,40656927,40704169,40746119,40796381,40839329,40908195,41016256,41068078,41118154,41174573,41213971,41296289,41336477,41374612,41416260,41469412,41520932,41568657,41622878,41669617,41727571,41836988,41960274,42028517,42079377,42131942,42255446,42322434,42382532,42440241,42495289,42553406,42612253,42675317,42717857,42803197,42850619,42891844,42945958,42989453,43033082,43072895,43116108,43157248,43202071,43245172,43317899,43354922,43414078,43470463,43522359,43565380,43602266,43648327,43683462,43770384,43858614,43950787,43990769,44046644,44100786,44139122,44178402,44222319,44268448,44352267,44402624,44456958,44515756,44573040,44732687,44866074,44902499,44930359,44964353,45004946,45042148,45082572,45175402,45224608,45266831,45315765,45408465,45453442,45507884,45549383,45592887,45719568,45763646,45810709,45854264,45894890,45941303,45987176,46040789,46095661,46137084,46172186,46213735,46256897,46347806,46391160,46438049,46477521,46518005,46558991,46607563,46666465,46721655,46770186,46818234,46867972,46999755,47088690,47162687,47277903,47312993,47350712,47394484,47465240,47494244,47581748,47648230,47689240,47773812,47861441,47904366,47935056,47978186,48066920,48114256,48208629,48251054,48297672,48402338,48504993,48575389,48645922,48688407,48737039,48785113,48826156,48868170,48914921,48991965,49037316,49077690,49131088,49182219,49256742,49350277,49399322,49453027,49506313,49600611,49647642,49694715,49738276,49776578,49814133,49852379,49942082,49986288,50024503,50063072,50107542,50149178,50230968,50268426,50301737,50321735,50350354,50380636,50415880,50447700,50486644,50530232,50577714,50622457,50664398,50712188,50751464,50803750,50845265,50888006,50923261,50962303,51077313,51125096,51163450,51206454,51244405,51279462,51379795,51413565,51445835,51476420,51551701,51601628,51761523,51798196,51851415,51903607,51941821,51984511,52043127,52254552,52307930,52360903,52414186,52458819,52504027,52589645,52635782,52731414,52782449,52826754,52873317,52919151,52984980,53050646,53107295,53166994,53236441,53300235,53364338,53444123,53508765,53582840,53643430,53745257,53795300,53844726,53890684,53942194,54000943,54051566,54111483,54163188,54213670,54256771,54384751,54436577,54480918,54540833,54595738,54639769,54682714,54718651,54763914,54805560,54892553,54942829,54980364,55026323,55071242,55108340,55150271,55190395,55228396,55301189,55362816,55401130,55465683,55507311,55569942,55611412,55653015,55701407,55766474,55801616,55836472,55875268,55910523,55948271,55987072,56037488,56081444,56115566,56142789,56174075,56213431,56246361,56290754,56339727,56436118,56517062,56621911,56666721,56703742,56743365,56773039,56811418,56849707,56889787,56924093,56965390,57011192,57053442,57096276,57129771,57156576,57186586,57219970,57253742,57291999,57328243,57364900,57401423,57482403,57591651,57622218,57660487,57702877,57775587,57825167,57867955,57960229,58013834,58058844,58142147,58178586,58218003,58259105,58340602,58381591,58427463,58459626,58494527,58607873,58663768,58717021,58776925,58824083,58873843,58926268,58984541,59028063,59088521,59131138,59162574,59251980,59286443,59398268,59445110,59483763,59528677,59573817,59615699,59660996,59737370,59832985,59879919,59938052,59988779,60031599,60072816,60116804,60172958,60261910,60305878,60364693,60425214,60489518,60550417,60603484,60658999,60700381,60745359,60785955,60829901,60880324,60964227,61018788,61067716,61112849,61148323,61182941,61259917,61320300,61369545,61403689,61476025,61514968,61562608,61596107,61635819,61675757,61711727,61751058,61846689,61892130,61937099,61984223,62022104,62057730,62107377,62152269,62187516,62223620,62264706,62341087,62376721,62408556,62452031,62493061,62576119,62623904,62678191,62725477,62781548,62838895,62914955,62992133,63078059,63124847,63170422,63212381,63263763,63310511,63443264,63479822,63621381,63667275,63703619,63746922,63790026,63825103,63860120,63902240,63937888,63985614,64037136,64080077,64123099,64166723,64212650,64263640,64310630,64353624,64458574,64517795,64564246,64621496,64679837,64723260,64748095,64787463,64825765,64900536,64938754,64974571,65006574,65086614,65137673,65193272,65291253,65372423,65412083,65450112,65480447,65517676,65555663,65593373,65624116,65659420,65690353,65764732,65806627,65850253,65883165,65923775,65955669,66006306,66048794,66097726,66142159,66178460,66224777,66265127,66301902,66343048,66514712,66554209,66595454,66640864,66716945,66750950,66793283,66841564,66894766,67015865,67148463,67184251,67296198,67333410,67373076,67412894,67462526,67506204,67540522,67575482,67679255,67729609,67781001,67828096,67913091,67951054,67986588,68027361,68060147,68100624,68138405,68188093,68242682,68292721,68341050,68384491,68438100,68484491,68538385,68591002,68641447,68683153,68724678,68759288,68797188,68826750,68902504,68944790,68989001,69025497,69072475,69116252,69153071,69184208,69268128,69313846,69346106,69450827,69486258,69530906,69585984,69637256,69683902,69732019,69776618,69821739,69867349,69908145,70024078,70058086,70095903,70127144,70162162,70205438,70247019,70302983,70340916,70369184,70401410,70436479,70476621,70509824,70551122,70596106,70666828,70703104,70795151,70879810,70954254,71016910,71054389,71084562,71115861,71154515,71190600,71229942,71269818,71315998,71349599,71390420,71483765,71523024,71561968,71634801,71673195,71714751,71769917,71813194,71847348,71880089,71914831,71945545,72057879,72087217,72170359,72207561,72387595,72441535,72491902,72549405,72611796,72665248,72712233,72766524,72806398,72847210,72886907,72926779,72965896,73012076,73047672,73082414,73125475,73175791,73265469,73303972,73332578,73364465,73481285,73515233,73550726,73598902,73640632,73681011,73721975,73756623,73793176,73855294,73895049,73933801,73979799,74023921,74071514,74113179,74147024,74186642,74229495,74299559,74352127,74382277,74408805,74445142,74481554,74511644,74553361,74599977,74646087,74718957,74751183,74779179,74809870,74843381,74873461,74902311,74936212,74969338,75003154,75031313,75073357,75143045,75174910,75212973,75240377,75281202,75317737,75352927,75375990,75402671,75431402,75505427,75603905,75641491,75678426,75714705,75810132,75847172,75872964,75897618,76039907,76074987,76111881,76134675,76165293,76198058,76236433,76264903,76286186,76318974,76347258,76407696,76432155,76500990,76539421,76571902,76596404,76623622,76652528,76683825,76793550,76827908,76871974,76916902,76961218,77005865,77054354,77117292,77141592,77179374,77210072,77237142,77292331,77318678,77348108,77395780,77431709,77465207,77499980,77530420,77605355,77640867,77676044,77712065,77758837,77887159,77934588;
The position of the SNP locus on chromosome 19 comprises: 333217,365630,388817,418323,448173,472149,495722,526607,544649,567432,571087,571776,580349,593428,617379,643927,678695,710421,744122,780445,816263,841854,870566,895711,936264,969314,1002883,1030902,1056426,1087734,1158293,1188237,1234532,1285224,1323282,1365440,1404849,1451240,1526881,1609291,1641262,1679466,1714528,1756749,1790855,1836273,1961297,1997375,2030512,2071396,2112839,2190097,2238840,2275079,2321189,2379146,2408486,2440257,2514637,2567544,2596673,2631318,2664358,2703523,2739678,2773952,2815560,2851901,2888304,2944953,2980541,3012557,3048987,3118311,3143155,3170421,3196285,3233942,3278501,3311283,3344960,3424853,3460513,3504829,3548439,3589994,3627489,3672629,3719135,3802531,3838037,3971291,4018052,4053179,4102132,4220969,4255456,4293973,4429155,4475270,4511599,4545141,4586217,4623857,4667234,4717447,4749759,4781471,4818931,4856393,4892175,4958237,5002011,5044085,5078921,5132388,5183322,5214144,5254372,5333645,5370047,5400642,5438935,5477108,5509976,5588826,5653736,5753709,5789854,5830447,5857466,5890385,5937097,5993896,6036286,6083780,6125729,6159014,6197141,6233818,6273862,6309562,6345258,6380891,6416916,6456497,6496351,6534621,6572403,6606814,6663916,6694109,6721842,6765073,6797340,6833072,6868657,6908111,6934430,6965921,6992638,7055106,7099342,7130975,7216669,7273492,7403489,7436596,7472705,7525823,7561410,7607289,7681351,7750637,7771846,7806086,7871045,7919275,7971854,8022228,8120508,8151800,8188436,8219737,8250502,8291672,8325829,8386701,8420456,8466792,8509766,8554718,8595704,8635575,8682594,8769490,8803335,8847934,8922441,8999661,9039166,9078190,9107432,9160244,9193538,9227726,9257120,9337929,9385241,9437763,9532823,9568947,9615168,9707677,9763350,9809820,9853392,9975514,10016711,10063830,10131042,10172327,10221984,10319988,10367122,10488083,10587021,10635196,10675334,10724518,10770783,10929774,11001245,11069229,11115611,11216203,11244430,11279922,11323671,11410141,11454038,11512727,11559777,11611215,11659322,11703012,11748849,11794235,11843260,11925871,11969298,12024649,12075874,12123623,12229149,12283461,12339986,12393130,12443177,12493781,12530471,12558538,12612223,12654503,12714618,12761426,12811424,12871720,12932039,12993354,13051829,13098993,13155947,13227354,13287415,13328058,13368530,13416251,13446966,13482584,13524902,13565165,13613965,13654067,13696683,13735273,13779664,13836935,13877855,13911573,13951830,13999740,14052951,14102388,14153272,14207024,14264490,14322077,14372013,14416055,14454121,14497609,14550295,14590270,14629150,14674499,14716708,14763603,14805519,14851159,14912718,14956197,14992226,15030981,15066245,15101602,15128250,15160909,15195284,15274293,15395111,15465211,15525301,15588280,15632693,15676197,15704229,15737392,15767906,15785815,15803081,15876401,15948112,16003762,16030155,16062599,16113007,16172395,16210756,16260302,16300451,16342214,16413987,16508543,16616586,16679435,16733554,16787913,16830424,16866966,16906241,16964570,17008621,17049767,17093518,17128128,17213558,17293208,17332241,17451631,17601175,17643125,17686657,17730281,17769112,17801502,17842620,17880823,17917753,17949204,17989362,18030309,18080931,18125530,18160426,18188681,18227847,18273632,18317813,18363296,18395112,18441089,18579028,18631256,18715082,18763606,18811879,18853592,18906514,18956480,19015163,19105648,19157258,19202406,19247150,19288885,19343764,19395464,19449719,19506092,19562332,19617584,19676257,19733331,19790136,19839557,19880366,19925478,19987829,20040338,20082137,20115779,20156249,20183404,20225562,20258857,20303068,20390578,20438906,20476088,20578850,20623939,20661024,20695021,20731368,20756848,20787087,20841168,20882249,20914908,20952994,20979882,21013329,21042037,21074329,21114015,21138459,21167817,21214302,21255780,21295067,21384837,21453098,21529560,21562285,21609644,21647791,21684024,21710962,21743324,21757004,21791494,21813402,21829611,21853849,21895749,21938744,21978741,22025850,22075230,22110610,22150192,22199277,22237041,22274262,22363826,22441375,22477174,22508127,22541239,22623385,22708248,22739060,22777553,22809642,22840839,22870903,22905167,22940289,23022284,23057886,23089316,23136441,23229962,23411952,23450164,23477634,23493335,23541279,23582114,23620195,23682249,23744094,23771585,23812093,23841796,23905601,23966340,24044041,24119278,24153503,24184663,24266023,24325906,24371998,24401256,24433047,24468186,24493314,24518388,24538166,24557857,24576799,24595969,27733912,27736631,27739566,27749513,27760169,27793206,27805071,27815966,27830181,27849963,27859151,27870404,27880987,27894037,27910620,27928383,27946876,27965996,27999875,28034173,28065083,28103429,28141101,28186307,28232530,28278119,28304854,28314479,28328080,28348880,28408912,28533064,28552507,28604705,28643579,28679530,28724108,28766232,28829580,28863597,28895224,28927150,28964795,29007174,29087519,29119424,29167973,29289360,29315856,29379241,29488786,29516482,29551199,29590357,29633323,29717108,29811429,29838536,29867634,29895775,29928871,30002164,30037009,30072276,30105427,30149012,30188208,30223721,30336114,30407773,30449011,30497224,30593306,30630116,30674705,30770688,30821354,30876942,30971238,31014949,31067458,31109023,31153836,31257903,31299388,31387275,31436381,31493257,31551716,31604205,31650903,31699205,31751259,31803182,31858112,31898451,31991889,32035320,32128986,32166846,32221206,32264216,32364649,32425030,32477672,32519463,32568315,32691312,32739156,32786725,32836430,32891260,32994913,33034798,33104850,33135215,33167139,33212781,33252036,33300852,33345945,33380038,33453659,33492820,33530517,33620108,33661975,33704113,33740801,33772177,33818481,33862088,33903589,33981813,34032149,34072953,34116970,34156992,34196744,34240287,34280115,34323406,34355502,34400886,34449212,34497620,34538340,34624114,34676982,34730032,34778354,34827027,34880020,34910916,35009953,35050270,35087449,35130010,35175775,35220245,35261114,35317509,35363016,35413262,35495291,35536552,35610585,35654576,35684635,35723501,35765877,35810074,35921908,35960975,36000180,36039845,36085513,36142861,36233470,36281603,36369626,36408197,36452274,36504484,36557627,36600727,36640014,36677710,36757407,36835601,36886380,36929190,36976379,37023044,37128706,37188952,37246594,37299673,37351280,37401804,37444627,37476949,37568536,37658723,37712530,37794753,37848678,37902059,37962374,38024683,38071752,38123980,38172015,38225658,38283126,38348149,38445868,38485272,38527613,38572375,38755864,38801927,38849866,38900309,38941401,38979746,39018917,39059898,39108707,39163969,39209635,39247810,39334673,39420194,39463400,39494342,39554993,39592332,39627619,39669105,39708656,39787649,39846962,39945281,40032132,40111229,40130502,40220764,40254851,40291850,40337715,40369649,40423919,40465733,40507965,40565454,40617533,40662203,40703065,40760408,40876520,40924446,41011261,41153042,41197399,41289586,41331426,41362791,41440669,41481762,41516467,41546731,41587028,41697071,41842875,41880408,41923456,41962076,42010059,42060551,42110221,42154735,42201921,42240621,42284905,42331992,42374397,42422806,42486792,42566314,42650069,42724785,42797959,42922932,42981068,43047387,43106936,43233284,43273404,43324298,43360185,43395723,43430593,43505835,43544190,43579023,43608812,43647965,43685435,43711898,43752588,43786846,43826122,43873376,43919808,43957990,44005061,44042774,44118353,44163307,44219103,44266001,44301400,44339595,44379321,44474275,44509685,44558208,44608072,44650819,44713407,44773450,44862022,44890006,44914769,44961806,44991595,45055451,45096090,45138324,45178307,45329130,45442771,45518223,45568838,45661378,45702063,45746139,45798379,45868478,45950557,45988107,46164875,46208212,46309203,46350551,46396233,46434424,46525572,46568855,46616742,46674304,46718510,46792915,46829213,46878654,46915410,46943030,47004485,47079368,47126548,47173310,47221115,47267825,47305060,47341827,47504601,47544929,47589796,47647212,47702467,47760987,47846396,47932868,47985757,48088780,48131563,48212423,48279789,48320010,48342796,48372766,48489092,48518435,48577047,48603755,48634960,48665886,48702182,48733015,48769804,48800107,48840562,48881876,48926521,48976497,49060804,49121923,49170275,49211068,49328753,49361887,49436513,49469999,49510512,49546270,49589580,49672539,49745407,49772689,49825114,49869197,49901125,49944406,50013045,50052907,50101713,50141504,50199885,50244048,50294150,50343129,50384677,50457915,50486440,50515579,50639592,50690475,50727391,50762026,50802352,50854091,50889814,50916605,50955797,51075229,51110044,51151884,51237200,51268873,51303866,51329272,51353402,51408048,51466447,51498778,51528980,51556369,51598406,51640321,51687117,51732844,51776229,51818413,51857128,51886935,51919502,51964405,51997809,52030370,52135282,52166387,52200895,52234447,52275320,52316365,52388502,52434342,52473606,52515293,52563493,52609099,52690861,52725979,52766726,52807790,52850660,52885421,52919433,52975070,53001952,53027621,53054139,53089016,53149316,53215353,53242581,53278027,53309844,53336209,53399832,53434266,53466424,53499505,53535998,53574937,53640390,53684403,53724825,53827213,53860876,53892073,53922453,53942397,53970930,53994611,54051096,54091144,54120241,54152311,54183704,54235271,54290659,54321535,54356811,54394921,54426191,54462073,54503483,54527012,54558592,54595216,54627915,54692523,54741036,54772569,54801910,54838294,54930431,54964487,55001670,55095273,55123089,55183553,55240313,55258412,55278569,55294329,55325543,55343895,55392814,55428444,55451890,55513741,55539193,55562141,55588006,55625244,55663288,55694651,55784221,55832567,55906182,55944166,55989204,56076673,56115714,56167254,56214410,56250653,56280555,56313579,56342133,56370685,56432444,56461381,56494378,56538150,56567056,56595076,56618186,56686368,56716395,56746678,56770267,56813520,56851100,56932600,56986822,57032495,57077384,57121269,57226464,57256233,57304307,57359343,57403766,57436700,57470132,57502544,57570042,57641887,57675951,57714070,57753640,57792711,57833233,57864599,58004266,58038303,58194647,58247262,58293276,58339578,58381999,58434902,58481265,58523804,58559413,58597968,58629146,58664043,58705080,58747818,58953099,58996147,59035022,59074255, respectively;
The positions of the SNP loci on chromosome 20 include: 76231,126490,154635,194028,226253,278287,311216,344079,368876,402921,443296,485864,528866,564539,598071,632959,670103,735675,762778,793482,821909,885145,946498,986009,1025211,1117419,1163936,1198626,1286677,1332126,1367375,1478465,1518843,1567395,1625050,1659527,1689474,1757124,1805801,1848856,1884817,1921593,1959940,1994963,2034011,2117153,2188753,2221897,2259303,2296223,2394951,2431187,2473130,2552926,2584768,2617701,2645199,2682621,2722259,2765082,2846052,2989384,3065916,3108821,3187733,3224441,3265308,3303225,3377889,3419052,3516425,3556641,3697491,3771651,3802357,3840895,3911486,3994700,4057208,4079949,4110118,4142966,4214235,4332056,4410060,4446349,4486839,4525272,4562141,4594621,4630610,4672269,4703957,4731591,4763378,4791677,4823105,4855407,4899684,5009143,5145693,5187110,5226792,5262051,5290160,5360197,5404150,5435549,5465528,5505764,5539599,5581202,5617855,5647585,5680741,5711154,5742469,5770527,5798080,5830582,5923204,5959423,5993466,6061001,6093749,6128495,6167407,6244211,6319701,6355786,6397127,6430197,6465141,6513729,6558282,6592950,6636978,6670053,6704437,6781950,6816151,6853826,6890074,6929369,7037509,7073713,7117112,7161056,7199354,7238234,7270766,7311413,7350779,7388168,7428907,7458474,7497772,7543082,7586366,7619092,7652465,7688601,7726541,7770976,7856868,7901880,7940440,7983819,8022783,8070295,8112497,8158758,8232408,8269832,8360690,8446700,8489609,8564072,8610425,8648450,8689441,8731871,8765627,8800237,8827539,8860630,8902793,8945875,8992726,9032650,9070147,9118903,9167192,9279233,9322989,9366431,9405829,9495379,9532365,9577066,9622750,9664763,9709701,9749737,9791092,9834706,9876266,9954328,9997794,10031342,10075428,10105067,10146479,10188476,10282188,10323470,10362069,10400753,10436952,10478027,10523896,10583532,10634970,10680221,10727804,10771838,10822368,10865458,10911411,10952823,10986818,11026038,11067917,11188441,11231706,11427959,11473151,11520024,11566458,11607038,11651059,11733680,11845145,11888860,11935024,11975974,12017394,12165437,12205269,12247367,12284535,12336258,12424870,12458016,12498211,12533539,12578226,12613973,12647588,12711939,12745441,12790468,12830215,12871799,12913871,12947955,12984042,13017192,13047557,13080187,13120180,13165406,13210187,13279490,13319869,13362832,13407322,13451006,13501314,13551319,13596877,13694313,13735103,13779964,13825033,13907000,13999548,14051055,14100277,14158220,14257876,14355281,14399677,14449353,14498396,14536808,14630963,14679462,14721834,14802007,14887370,14926333,15008521,15052595,15085365,15124621,15163633,15250804,15295532,15333378,15374019,15411684,15449761,15562411,15598740,15637975,15664481,15738540,15766818,15802476,15877159,15914748,15952124,15987595,16025289,16057952,16095372,16135517,16173543,16202400,16231666,16285161,16332845,16379705,16455165,16493467,16529669,16562284,16600240,16633844,16665236,16701635,16740721,16776513,16853683,16887205,16933588,16970535,17010348,17049049,17133350,17171373,17219647,17263853,17310016,17335528,17371358,17414090,17445288,17478197,17515122,17555887,17594970,17630456,17668196,17739972,17768057,17802070,17836267,17864717,17898450,17934433,17967947,18005708,18040814,18079555,18119044,18162171,18198700,18237120,18276308,18325121,18406931,18447960,18487014,18528254,18563268,18606512,18687154,18765897,18801733,18847381,18889609,18929374,18974548,19012326,19053189,19099554,19141198,19196157,19236526,19277454,19353136,19393323,19427837,19460406,19541114,19582650,19669866,19704554,19781023,19811114,19849409,19879040,19907729,19940732,19974317,20082738,20161816,20201583,20248232,20283768,20329470,20407769,20462193,20531201,20587277,20645845,20757345,20802274,20835517,20881786,20964602,21006074,21048457,21139126,21185516,21237771,21292260,21346241,21403493,21458169,21515160,21560039,21607578,21700286,21754131,21801469,21842421,21889138,21936384,21988792,22037409,22082519,22127647,22172803,22272385,22340617,22382101,22424075,22469934,22507891,22541476,22581413,22629319,22669325,22703424,22741915,22775615,22808975,22836623,22872257,22918468,22962946,23000704,23041581,23079139,23150342,23198152,23241368,23276385,23315371,23354749,23390206,23432310,23461790,23499536,23534722,23607578,23642458,23681920,23716646,23745039,23777061,23805686,23838326,23877201,23917218,23952156,23976159,24006761,24041799,24077481,24117791,24154736,24188891,24218802,24261334,24291580,24405369,24432810,24517982,24563285,24610455,24650409,24681395,24721102,24751833,24820108,24858215,24895108,24928678,24958897,25000886,25046095,25089672,25157288,25195019,25235961,25270291,25307574,25354705,25397157,25435470,25474410,25569523,25662181,25738817,25758324,25836746,25847129,25865078,25878818,25889300,25899613,25909257,25923194,25937033,25952148,25985998,26074197,26087050,26103544,26129447,26140578,26147555,26189930,26205221,26214519,26244864,26254915,26261165,26270948,26277847,26293748,26302279,26310569,29421199,29428898,29437303,29448160,29456999,29469319,29481803,29493172,29510464,29530693,29548020,29560935,29573572,29583014,29588429,29593580,29598742,29605592,29612191,29618839,29624663,29630249,29636064,29645603,29649917,29805106,29814806,29827092,29861881,29959263,30089517,30135216,30177852,30320883,30372106,30423968,30475091,30571286,30659815,30705786,30799856,30845459,30892434,30944258,30992048,31042894,31089109,31147792,31196420,31236411,31278459,31310780,31346952,31379665,31458135,31497052,31541419,31584178,31620690,31656087,31695058,31734430,31775687,31813617,31921951,32011965,32120607,32174542,32283610,32335449,32380914,32438656,32479283,32515393,32607593,32716967,32777258,32835742,32878452,32931890,33087166,33147715,33203720,33302194,33361721,33477248,33524626,33568595,33611208,33647738,33728949,33825157,33869468,33919320,33971876,34012228,34102295,34146742,34180535,34228866,34280309,34411239,34500823,34559513,34610819,34718171,34767821,34832137,34883099,34996454,35047166,35100779,35155478,35204504,35244723,35291989,35347361,35445693,35497799,35589544,35628299,35680126,35731416,35780069,35820867,35859623,35900289,35987638,36054673,36099623,36190375,36224534,36250633,36288025,36324104,36371134,36516792,36559234,36599753,36656066,36757777,36792405,36826793,36874184,36953103,36984610,37012928,37057418,37162165,37212966,37249224,37280490,37318089,37359371,37396120,37432356,37488539,37534369,37584129,37684631,37723807,37771164,37879249,37926387,37974189,38101893,38148112,38191361,38235569,38272282,38305778,38354740,38398518,38454823,38495617,38545582,38598670,38644589,38686712,38820105,38862775,38905667,38954983,38989455,39033223,39079348,39122944,39168525,39214759,39263720,39300665,39343613,39379737,39414995,39456775,39540605,39583952,39669419,39723683,39784220,39886424,39935879,39986753,40134206,40188691,40246386,40297421,40342014,40388422,40430931,40515546,40558187,40599614,40678491,40717079,40754235,40795349,40924773,40968418,41003563,41042770,41077356,41111143,41145681,41185138,41227563,41264229,41309872,41342792,41384278,41424190,41503269,41683466,41724388,41762963,41804309,41846674,41892410,41937455,41983470,42022294,42091071,42130132,42175935,42213013,42287313,42321828,42359295,42536512,42616004,42652072,42724814,42759640,42797013,42835757,42869068,42908169,42951355,42987281,43025595,43062416,43115517,43168828,43224074,43268000,43305163,43342929,43379404,43431368,43480100,43518165,43561588,43605040,43689097,43733565,43774556,43823127,43902809,43931724,43959347,43991255,44028483,44096817,44137620,44211104,44245971,44290985,44338769,44423683,44458998,44495553,44527602,44566343,44642396,44729404,44801943,44843099,44892070,44936481,45023160,45109611,45191364,45223130,45307144,45354185,45385268,45487091,45525464,45559557,45595494,45629822,45661428,45695612,45731955,45796857,45863762,45905651,45948289,46071371,46113217,46145250,46222860,46265090,46298918,46337393,46369908,46397250,46429806,46468915,46496744,46524233,46634480,46672590,46715943,46757521,46792919,46830201,46857755,46890637,46929269,46966590,47004320,47063176,47094250,47130047,47145162,47177304,47211336,47246477,47281853,47320176,47402805,47448380,47494102,47524997,47570114,47625986,47673251,47711285,47749548,47792246,47908663,47951504,47994537,48079726,48125462,48164885,48204416,48272475,48349391,48382914,48412945,48489791,48530225,48563751,48598089,48634713,48674725,48712918,48752490,48868550,48909667,48952832,48992586,49032480,49067246,49101677,49137446,49229473,49299853,49339418,49379064,49409173,49489386,49530536,49575021,49613583,49655483,49695511,49736430,49776438,49807995,49852451,49887639,49927240,50000969,50027059,50135529,50173331,50208036,50246869,50273045,50305063,50338810,50398662,50433347,50497125,50529156,50569252,50604076,50641692,50676763,50711018,50740423,50779420,50820444,50868916,50913176,50958166,51001483,51036785,51077117,51134889,51179082,51231557,51266440,51303915,51372101,51415799,51460221,51554687,51711538,51748950,51787072,51822731,51862148,51906004,51946605,51984117,52027231,52107618,52142498,52206594,52247621,52315893,52385470,52419641,52451654,52478264,52491227,52526261,52560758,52598078,52630442,52730640,52793352,52822006,52895224,52926083,52960114,53004574,53041094,53078023,53156696,53195916,53262368,53289631,53316146,53347625,53390951,53431044,53461702,53495179,53528705,53562594,53597495,53629833,53665450,53690053,53714627,53756881,53788165,53822173,53859097,53893219,53928270,53973293,54013142,54091286,54124517,54151354,54187005,54217637,54270300,54301289,54334796,54368355,54397792,54432293,54503042,54540328,54574793,54626600,54671792,54716125,54824557,54855648,54887180,54967460,55008092,55092245,55130395,55166534,55206557,55241958,55276679,55307372,55345717,55380506,55417746,55451437,55478220,55511788,55542429,55579120,55609158,55640387,55669341,55734779,55767965,55802055,55843309,55893741,55934205,55974779,56008212,56042205,56074907,56113304,56146106,56180285,56285845,56326759,56365171,56404310,56433823,56466688,56497277,56527638,56633481,56708705,56745038,56772887,56815554,56858907,56898134,56980800,57021541,57101616,57139066,57172970,57206736,57290484,57330456,57368464,57412067,57456914,57493824,57539105,57572709,57616974,57705485,57793382,57877621,57917108,57957238,57984718,58018437,58057317,58090071,58133512,58164790,58206004,58283170,58320369,58353445,58389899,58435901,58484630,58538862,58582415,58662650,58688046,58723958,58760520,58797648,58835470,58935468,58979726,59024655,59061433,59102674,59197174,59238429,59297791,59329911,59360715,59399952,59437716,59471696,59507067,59545213,59582890,59616556,59645097,59676675,59708314,59749781,59783700,59818916,59884435,59912480,59942013,59968829,60003841,60032848,60076205,60110021,60140297,60167790,60205058,60234142,60293382,60318823,60352065,60376752,60412032,60443445,60501137,60522482,60554263,60585979,60689943,60728912,60758143,60789134,60832315,60869733,60957331,60984143,61018383,61051373,61087771,61168787,61190180,61342777,61371078,61403330,61437448,61465614,61496338,61534794,61573811,61607275,61669558,61706197,61734711,61765988,61847068,61880462,61919444,61981605,61998174,62028764,62063592,62095147,62127584,62190235,62216523,62241284,62275684,62308971,62343164,62402403,62437656,62470518,62593837,62633096,62680560,62723006,62756897,62770113,62833410,62872504,62908917, respectively;
The positions of the SNP loci on chromosome 21 include: 9416284,9572394,9651138,9677401,9832928,9849330,9863658,9893658,9970657,10012454,10086615,10381158,10423379,10476027,10550411,10612394,10702657,10707253,10712760,10716977,10722209,10727842,10735069,10744581,10750951,10763444,10774667,10785259,10797426,10810260,10841061,10858412,10886173,10900557,10930816,10965010,10999871,11029624,11039583,11046937,11055963,11061900,11066736,11072874,11078949,11085032,11092625,11100487,11109037,11127556,11133391,11139752,11155287,11186474,14342793,14350725,14359615,14368228,14390732,14412607,14473305,14561413,14636381,14683989,14735691,14752721,14778628,14844013,14946397,15062577,15229407,15247788,15266036,15288836,15314609,15336061,15359883,15403323,15438560,15457131,15483570,15530499,15607071,15631164,15655879,15692235,15719061,15791600,15865732,15936132,15964119,16002707,16041439,16097382,16133904,16162316,16195204,16242611,16292880,16345459,16383824,16427140,16498243,16535340,16580580,16780693,16814655,16895833,16935979,17016189,17053737,17160587,17219626,17272621,17332040,17372295,17411568,17467068,17522932,17599603,17670740,17746503,17779717,17821761,17860640,17905657,17995449,18063466,18110478,18154879,18196761,18231769,18266662,18301488,18335180,18375287,18407931,18479249,18560660,18626747,18669299,18794776,18826103,18857579,18896246,18931996,19005148,19050836,19082650,19126114,19267585,19339772,19422865,19499647,19564149,19612107,19645612,19816402,19864918,19904121,19942993,19977568,20024746,20065362,20105756,20139532,20179718,20212168,20241238,20284399,20317173,20354867,20426661,20462960,20508381,20549131,20591768,20638853,20682862,20721513,20773035,20823979,20904052,20969012,21006237,21050623,21088065,21128712,21176350,21211922,21243867,21286764,21368653,21447155,21527063,21575280,21618216,21663474,21695594,21839242,21893779,21966649,22122519,22151343,22193748,22233898,22351225,22382654,22417847,22481258,22510510,22557344,22596660,22635834,22710878,22751582,22793671,22864581,22940247,22981624,23022267,23061004,23227031,23274075,23308230,23347227,23380159,23424863,23480036,23538540,23638314,23751023,23829508,23874595,23925128,23952969,23996052,24029647,24066559,24102973,24150495,24220855,24261926,24313144,24363436,24405219,24444768,24481855,24565963,24600149,24640948,24679281,24718762,24760134,24797757,24828283,24865272,24905803,24935729,24971650,25003931,25049198,25093869,25187933,25218455,25251387,25284069,25322824,25358203,25389929,25414932,25439151,25460946,25485874,25513533,25546742,25579252,25627810,25712819,25753316,25803548,25846856,25889287,26017036,26054675,26095504,26169765,26210572,26257674,26305241,26349805,26392038,26446909,26504207,26552889,26591545,26684805,26799570,26847893,26904460,27029994,27118846,27155126,27182334,27212854,27249438,27317608,27348258,27377350,27405308,27489236,27533710,27573949,27622881,27661345,27697893,27742979,27786815,27834624,27935606,27979861,28015738,28124222,28169135,28210693,28248386,28293795,28341064,28382377,28449564,28490550,28558901,28591649,28629740,28669825,28710016,28745624,28786756,28819930,28864855,28905881,28959524,28999877,29121129,29168505,29209183,29248875,29297616,29335537,29382257,29426941,29457416,29487089,29514609,29554601,29592650,29702063,29738422,29768805,29801621,29834691,29917879,29953927,30031175,30076890,30109148,30137916,30178277,30219973,30251205,30338456,30384933,30433276,30628120,30686902,30737237,30785629,30835483,30865729,30967878,31004309,31045052,31091928,31135490,31177557,31218381,31248431,31290765,31330769,31418192,31509099,31545508,31589081,31621684,31662152,31703987,31744287,31790514,31833544,31883080,31979790,32037484,32075985,32104291,32150431,32196671,32235858,32378145,32421417,32449036,32490292,32568980,32603457,32650871,32698392,32737704,32771597,32806714,32843665,32919790,32962502,33000955,33043732,33094040,33143483,33181112,33224196,33255472,33329332,33360859,33427300,33464397,33499611,33542897,33580136,33631793,33676558,33719434,33766594,33804929,33838266,33880318,33971244,34022261,34141593,34187695,34245761,34338366,34377552,34422353,34575721,34644897,34672938,34708622,34829570,34872238,34930179,34988002,35048741,35105880,35163031,35221267,35295810,35340999,35376025,35414404,35538892,35580048,35625529,35674046,35720456,35754839,35786524,35826535,35862484,35929628,35966757,36011975,36050247,36133848,36188764,36234671,36279819,36323507,36447091,36525506,36566379,36638306,36678343,36886779,36959163,37001408,37031102,37071840,37116730,37177059,37290025,37357822,37442116,37479914,37514392,37548398,37624774,37662367,37768962,37816000,37848603,37920907,37956263,38003532,38040461,38081966,38126275,38170033,38214157,38254177,38345727,38561918,38602760,38651907,38688804,38725582,38773784,38862376,38910581,38958104,38996789,39035897,39064093,39102048,39145410,39238945,39285456,39383865,39434993,39539266,39589945,39634109,39673704,39717703,39807036,39844788,39897807,39937289,39974870,40014437,40060268,40152372,40190412,40225683,40260709,40298609,40337613,40401135,40432520,40499915,40544464,40580451,40619656,40657169,40690397,40723011,40764066,40809028,40855439,40893960,40924056,40955751,40988612,41062838,41096818,41127172,41155350,41190444,41256058,41287202,41323477,41351895,41383840,41424162,41497349,41532739,41565047,41596831,41637122,41671275,41717537,41838994,41904600,41935061,41994797,42018997,42068138,42105800,42141147,42180961,42215370,42253855,42288948,42324573,42373258,42474210,42508856,42548719,42637222,42678029,42721722,42761102,42802447,42831593,42941502,43028392,43069311,43101272,43132579,43161805,43225714,43255908,43288345,43327676,43399915,43443570,43470695,43498930,43532853,43597934,43637349,43679554,43715047,43752969,43782430,43848186,43884666,43931364,43972478,43995088,44026272,44061266,44095690,44136884,44173148,44206616,44249381,44279393,44385887,44415885,44453703,44479324,44514315,44566869,44601086,44764719,44798699,44830979,44868960,44919668,45123364,45163060,45196121,45229577,45260610,45298501,45342204,45387665,45430904,45482041,45572061,45608071,45635719,45669863,45734229,45772635,45812326,45839498,45869515,45916235,45952553,45989795,46013349,46045124,46075092,46106397,46138768,46171571,46205464,46244765,46268652,46330487,46362691,46393533,46412027,46441829,46475940,46523623,46566470,46614186,46657243,46686708,46764460,46795235,46827478,46904833,46928976,46958586,47165936,47213476,47252759,47291103,47318259,47344494,47374985,47430931,47485424,47510972,47544453,47561218,47613175,47651023,47687254,47713070,47746649,47785323,47817563,47842336,47878671,47917664,47955559,47997129,48033490;
The position of the SNP locus on chromosome 22 comprises: 16057288,16242751,16444659,16620586,16852685,16856595,16868364,16885814,16903325,16918399,16939393,16956851,17013924,17085746,17125738,17194240,17237414,17333650,17357915,17372703,17381841,17396176,17430558,17475942,17504077,17535049,17573272,17607174,17665135,17774161,17808961,17841198,17877906,17908596,17936616,18076467,18106823,18135129,18174781,18211329,18277438,18311300,18432033,18458035,18483013,18515631,18553028,18585820,18657355,18778156,18875965,18883566,18905328,18943415,18974986,19051371,19086904,19163047,19199403,19247209,19291766,19404733,19449571,19496423,19609106,19640667,19678313,19757010,19793593,19844234,19882630,19911619,19941947,19972935,20018969,20059344,20103462,20149985,20223508,20629154,20713559,20753223,20783721,20830422,20874540,20986448,21062296,21109206,21150840,21233783,21272897,21345091,21375994,21419163,21451951,21575930,21928597,22020483,22055589,22093837,22139208,22183980,22367697,22400049,22435054,22463754,22489560,22518338,22550401,22572034,22599953,22624656,22656699,22687958,22709354,22729306,22783396,22916243,22947837,22983489,23047893,23066978,23100385,23125650,23166939,23206697,23236406,23297693,23340805,23391131,23451356,23493873,23530961,23602419,23669372,23701581,23762264,23790919,23818837,23846492,23900837,23970897,24000068,24079724,24117959,24149768,24177636,24212056,24240089,24269519,24324016,24372494,24496099,24562398,24643540,24688968,24736280,24842098,24891166,24931625,24979004,25034777,25072287,25153606,25183877,25218912,25251671,25284552,25317044,25354656,25390270,25444874,25483767,25523876,25564047,25602790,25631756,25660119,25729594,25761936,25804453,25832687,25909119,25974887,26017001,26078646,26168894,26228942,26265357,26334249,26380596,26409140,26450986,26493132,26584585,26662382,26697195,26730293,26793073,26828619,26865058,26906216,26945788,26982424,27028313,27093674,27176574,27215701,27248223,27284036,27319646,27349278,27385279,27483480,27505558,27541354,27574903,27615461,27648408,27718759,27751796,27784836,27815619,27855798,27891917,27925722,27961612,27999372,28029538,28061578,28099616,28141113,28220424,28341053,28395422,28453818,28521553,28588692,28655314,28721065,28782960,28851868,28908195,28975913,29036303,29091443,29128013,29168360,29209728,29249525,29295898,29351034,29409445,29456360,29490668,29522251,29555480,29636985,29678569,29731755,29777146,29889650,29934120,29973634,30018643,30068570,30121500,30167931,30216900,30255462,30296059,30337335,30422468,30585746,30684787,30740157,30843355,30880262,30917825,30957832,31002638,31063617,31159625,31205912,31254555,31369636,31423708,31466685,31508195,31647724,31694861,31844293,31882278,32017509,32108997,32160708,32214274,32259855,32301770,32382309,32470485,32526658,32568831,32599540,32641683,32681058,32706509,32757417,32783210,32847759,32884942,32921697,32952699,32984761,33017539,33057006,33118615,33158093,33182004,33218431,33263931,33299596,33348284,33465413,33510161,33543050,33579610,33604051,33650660,33687940,33763746,33842875,33880290,33952694,33992541,34031333,34070819,34107919,34145831,34180801,34217687,34290257,34370403,34540680,34573465,34642027,34683829,34725083,34844073,34881535,34909133,34945097,34980085,35022040,35059183,35099134,35143901,35228878,35308678,35345623,35381546,35455664,35488540,35531612,35562148,35635864,35679787,35720198,35758742,35793266,35830470,35860563,35893900,35929749,35967818,36031861,36101450,36131158,36265616,36326172,36382858,36438869,36478989,36522134,36559476,36584260,36615706,36654145,36730947,36779064,36854851,36889485,36922997,36953965,36987577,37024359,37061519,37098913,37133413,37171795,37207484,37241090,37273205,37345923,37406778,37450840,37490714,37522525,37591373,37620663,37648151,37681968,37721217,37752697,37792590,37825180,37870939,37912754,37988349,38031491,38072876,38156518,38196474,38240841,38294830,38349525,38402956,38496556,38528391,38563541,38596646,38635486,38680816,38772004,38819028,38860740,38907849,38964460,39062007,39111812,39160569,39204683,39247333,39286923,39322400,39360018,39395101,39428958,39469000,39499072,39575931,39607698,39642338,39677317,39712936,39744254,39778327,39817348,39863980,39909121,39951454,40029845,40075834,40124460,40180308,40373570,40414607,40507074,40549566,40603363,40650617,40712637,40759034,40813063,40862885,40915813,40972769,41028308,41076141,41204323,41245806,41307588,41363730,41408697,41448195,41494994,41536320,41584928,41627073,41669738,41718696,41771306,41815305,41855949,41911621,41962626,42013434,42051167,42091013,42134786,42175283,42221951,42266168,42362560,42413978,42456140,42501630,42530096,42557991,42706035,42753014,42820191,42865011,42905119,42939245,42972441,43016259,43045458,43075948,43100238,43129179,43162286,43191404,43227257,43259338,43295560,43332917,43372780,43415273,43440400,43507163,43543462,43570068,43595931,43631079,43672183,43702268,43839229,43872598,43924876,44013348,44056176,44102016,44202556,44285069,44316789,44353447,44389400,44428015,44471389,44506233,44624734,44653289,44678726,44706814,44750693,44784753,44816777,44844243,44927476,44951812,44992632,45023250,45055584,45084259,45120084,45142177,45226519,45253953,45298174,45332310,45371568,45439659,45504764,45537472,45572370,45606511,45638165,45696672,45736087,45776576,45817438,45855171,45900865,45933740,46000105,46037048,46084192,46136298,46178991,46334281,46364150,46405845,46450616,46499702,46533658,46572063,46690141,46730215,46763822,46793783,46829197,46861091,46891122,46919495,46949538,46978509,47004179,47067547,47100250,47133580,47167510,47207475,47248289,47282589,47376559,47413929,47445095,47474013,47510793,47547265,47571342,47603829,47642162,47677211,47745086,47770651,47800611,47831067,47865923,47902521,47939486,47976253,48006248,48042907,48073595,48104604,48135383,48172174,48207318,48239482,48309921,48335187,48374222,48411777,48442453,48476049,48511936,48549166,48581558,48615590,48646439,48680069,48706642,48734161,48757226,48784485,48861523,48969991,49003154,49028413,49050237,49068935,49090646,49114275,49136285,49165390,49190094,49215182,49268705,49298491,49322938,49340692,49355550,49375523,49405431,49429681,49459958,49482299,49507434,49529438,49551620,49593552,49618978,49645065,49668630,49691071,49709694,49740616,49765146,49801544,49853908,49887600,49916560,49948433,49985751,50022958,50056891,50084219,50114083,50145334,50182704,50219119,50258016,50294378,50322324,50458283,50487316,50510849,50546418,50576193,50604854,50643085,50678701,50715029,50760505,50820836,50893806,50930802,50964018,50997145,51064169,51096831,51181563;
The position of the SNP locus on the X chromosome comprises: 2247736,2723056,2726647,2772772,2818489,2853865,2925833,3050788,3106679,3156087,3221937,3264863,3379301,3461933,3528085,3581242,3628842,3741069,3919914,3974752,4035440,4112317,4175504,4241143,4426343,4596138,4659861,4797471,5024589,5076991,5243292,5336596,5408033,5660963,5778980,5920769,5996660,6075482,6234899,6314024,6407568,6770687,6850716,6944028,7038170,7139497,7489784,7599241,7858400,8172307,8271791,8357913,8498794,8583601,8878203,8991176,9098482,9218998,9292510,9374087,9421049,9495259,9589148,9679669,9753062,9836993,9913522,9982928,10088483,10173531,10269804,10365923,10520521,10656768,11050645,11229398,11364558,11497575,11604276,11709018,11825275,11935961,12218532,12313140,12488668,12570439,12631386,12730782,12802363,12885578,12949971,13022987,13114747,13234580,13618680,13815840,13970038,14079164,14185658,14325565,14444879,14581627,14663000,14864661,14978036,15069346,15193414,15360037,15436616,15529726,15621753,15727488,15819715,15923627,16038611,16170722,16249951,16555776,16700683,17105212,17223673,17366234,17508025,17777984,17917292,18072162,18199514,18339898,18493996,18671639,18763318,18852335,19100354,19300218,19542285,19770845,19894793,20045436,20175657,20312827,20428942,20558145,20680893,20788936,20997004,21132439,21277318,21458070,21665268,21809203,21917207,22005458,22087152,22179283,22259792,22394838,22537140,22618265,22700424,22779144,22910949,22992387,23073087,23163525,23230758,23298463,23387866,23472193,23560462,23645556,23908073,24004215,24086475,24179254,24340662,24566424,24647839,24754655,25014016,25135691,25193978,25303466,25581514,25693805,25778619,25859671,25941333,26152681,26239589,26355789,26462840,26584392,26714878,26823884,26922358,27000293,27075302,27161613,27256177,27449542,27600689,27676641,27767127,27882754,28001188,28321826,28450873,28533665,28658580,28769283,28850298,28949893,29075877,29167569,29268015,29398264,29796253,29904705,30145792,30250323,30347137,30448975,30538701,30635150,30801815,30923357,31008479,31092052,31242967,31323365,31481840,31574895,31687218,31774154,31854956,32026645,32096656,32257197,32322111,32395073,32468849,32539807,32662118,32739771,32888876,32962172,33028279,33089243,33160529,33254721,33355913,33448052,33555648,33648477,33762633,33863914,34061389,34160077,34265223,34382963,34462232,34651771,34744640,34825215,34988299,35065946,35314050,35526044,35620221,35822378,36141199,36369132,36473338,36600315,36687987,36788407,37039205,37212354,37416876,37530619,37737278,37827731,37913861,38021993,38133578,38262956,38333236,38399317,38509179,38625654,38748735,38861559,38973645,39105874,39231086,39354714,39681250,39780781,39888989,40001908,40101255,40203306,40285704,40374658,40457146,40657954,40768393,41035059,41127924,41284554,41361176,41481418,41643603,41795650,41916490,42133876,42289767,42565976,42670217,42784349,42880337,42979192,43136772,43408101,43636014,43765185,43877162,43982659,44226439,44321963,44481995,44789114,44905277,45034831,45245165,45508861,45601943,45957656,46088273,46193261,46285456,46400213,46528805,46642066,46791335,47174276,47498518,47625257,47730342,48014034,48149309,48457737,48566194,48732343,48875619,48980062,49071964,49161970,49496558,49630637,49758011,49897658,50451821,50671082,50783179,50910987,51178055,51303187,51434857,51618721,51745507,52569824,52680983,52891880,53097678,53218927,53356380,53513626,53910400,54095207,54426674,54541444,54771344,54893413,55122411,55238639,55341561,55476740,55652971,55731858,55850745,55912007,56007046,56093292,56184351,56482346,56599025,56680500,56780691,56949803,57077761,57274779,57369157,57475006,57557872,57812382,57923990,58064534,58139245,58258276,58359259,58419799,58460132,58487396,58516652,58546967,58562693,61686636,61727367,61731050,61734450,61756619,61774199,61800641,61817387,61837430,61853319,61872827,61886975,61915274,61960631,62085069,62197802,62411198,62954218,63137120,63271012,63355773,63435940,63579784,63700053,63767963,63975278,64091357,64219476,64362016,64438517,64671405,64815536,64948323,65087342,65308182,65416087,65521139,65601657,65676157,65761831,65862003,65986311,66127648,66255263,66351161,66457015,66566096,66681845,66855958,66983983,67079600,67177932,67408506,67653014,67787331,67894900,67993236,68090762,68189219,68315938,68408301,68509969,68596458,68697588,68832306,68959774,69175270,69287323,69395699,69508744,69640003,69865285,69990305,70100630,70178413,70362956,70438608,70691198,70846383,71129266,71369602,71472881,71562740,71739209,71897470,72274506,72397531,72499787,72715551,73098352,73231553,73359492,73487125,73582627,73699600,73840426,73983025,74154287,74288514,74400345,74530888,74621195,74729354,74834441,74940143,75063329,75106748,75172103,75324037,75410927,75489592,75591888,75730864,75882445,75943064,75996534,76070979,76115897,76171980,76257806,76267483,76412601,76515277,76831954,76976340,77158147,77343278,77482778,77614005,77725648,77798547,77931072,78153391,78256387,78374905,78478141,78574081,78629853,78720152,78805965,78905411,78970775,79052174,79097882,79143017,79219879,79348195,79445710,79561287,79715551,79792940,80043138,80343181,80480650,80785698,80899134,81042877,81138977,81251722,81358449,81479189,81644360,81745962,81832970,81939541,82131129,82236358,82329314,82435241,82573698,82716544,82866911,82999681,83138950,83270093,83377359,83509098,83627869,83713475,83789693,83867298,83971373,84222236,84332857,84424643,84542343,84660945,84823662,84883515,84955255,85018323,85125425,85215758,85324321,85392150,85548953,85619905,85738246,85820881,85912303,86097156,86174383,86253775,86330673,86393797,86499898,86569710,86632077,86707786,86793474,86874220,87047738,87118741,87285187,87383275,87468387,87531726,87572988,87622982,87681846,87740705,87796983,87891061,87984100,88174381,88264737,88346834,88419781,88514421,88721524,88786664,88847614,88897073,89028813,89102107,89181362,89247530,89335584,89400707,89463092,89518354,89578272,89637861,89688777,89760303,89820040,89879125,89937707,90003220,90069456,90133349,90209297,90273306,90335061,90484785,90580348,90687207,90828688,90956906,91187700,91324946,91363755,91527762,91575474,91625647,91758818,91818708,91947974,92007907,92083330,92133157,92200854,92252891,92304557,92353261,92413353,92685644,92752089,92825885,93060122,93167552,93264076,93346427,93423002,93596095,93780313,93897106,94014903,94097292,94189382,94282356,94375081,94455637,94655782,94777039,94892333,94993102,95092667,95239914,95319527,95540353,95607330,95718391,95815227,95903084,96014318,96090793,96203190,96339699,96434755,96529410,96647727,96784023,96892106,97209636,97306908,97409778,97531050,97777683,97880585,97993450,98112677,98244967,98489683,98634884,98768317,98883862,99030999,99132620,99228188,99333238,99561814,99764645,99882543,99971352,100071301,100347118,100435355,100534438,100609438,100673586,100791617,100897984,101018561,101217305,101303220,101399025,101923418,102047079,102167613,102297849,102395978,102493441,102609488,102739586,102868950,102979095,103047606,103137615,103531511,103687472,103838055,103978079,104127507,104252681,104565350,104685898,104830130,104946614,105225843,105344924,105490973,105661527,105958939,106256388,106362430,106480937,106620310,106780618,106910255,107026805,107162475,107284339,107425309,107545662,107763538,107845115,107929301,108037290,108111049,108293470,108399575,108491687,108616957,108744008,108858688,109005318,109095000,109201721,109329902,109508834,109710502,109816218,109912294,110003600,110138513,110285720,110422204,110559643,110697306,110851322,111012035,111242944,111356910,111462376,111534036,111636471,111734920,111932083,112067381,112256579,112366947,112452147,112553469,112657423,112770310,112864203,112941009,113059660,113147877,113261156,113349619,113481339,113624829,113741944,113861510,113968909,114061198,114244548,114605041,114709751,114789361,114891664,115014610,115100792,115223760,115311011,115397111,115481604,115775851,115863438,115940364,116001898,116095179,116168464,116231302,116457865,116528251,116587390,116651039,116754839,116820686,116905279,117105512,117216102,117368703,117449641,117526021,117688822,117809414,117969872,118041750,118121382,118206620,118495542,118617649,118681825,118756484,118840392,118892474,118954012,119029054,119104380,119406962,119591135,119818275,120005338,120344340,120580478,120693514,120940070,121030445,121128552,121219659,121312708,121475780,121556308,121819527,121896909,121980159,122163503,122265252,122360725,122473332,122584172,122696559,122812180,122868557,122919621,122996252,123273413,123421001,123518852,123711355,123823890,124003799,124124103,124222516,124306181,124405240,124495416,124585335,124661034,124736106,124824611,124940100,125055100,125146744,125238194,125435231,125507565,125606370,125680230,126072482,126182527,126371135,126455182,126564476,126665727,126748679,126809636,126909753,127169217,127276021,127376997,127494763,127638011,127873425,127959242,128052297,128134757,128246124,128347294,128425453,128518182,128636472,128743228,128903472,129560425,129644583,129751234,130123120,130255991,130380462,130492122,130604660,130716953,130847166,131026517,131131827,131388718,131542498,131719473,132092023,132219575,132367014,132610554,133001689,133165103,133492339,133596418,133662605,133772306,133919538,134166632,134669316,134786450,134975438,135096039,135199177,135305804,135458848,135565593,135805503,135918726,136012789,136130499,136246693,136359020,136446829,136747199,136851415,136967494,137180011,137293810,137384309,137484331,137577916,137690086,137832884,138151701,138255170,138330926,138424492,138600830,138669578,138759178,139086172,139155386,139330678,139636645,139721973,139894872,139977743,140050689,140269630,140358350,140442074,140506439,140697174,140780527,140930467,141086936,141154190,141216789,141287277,141362523,141447156,141614525,141679795,141740128,141811816,141899797,141975671,142159350,142265721,142347861,142445351,142562505,142632686,142708882,142789028,142867071,142958662,143051956,143153877,143340207,143407745,143735678,143819163,143917456,144009483,144087996,144166886,144246695,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In a second aspect, the present invention provides a method for assessing genomic abnormalities, comprising:
selecting a plurality of SNP sites according to the first aspect, and constructing a capture probe or a kit capable of capturing nucleotide fragments containing the SNP sites;
extracting DNA of a detection sample;
constructing a detection sample DNA library;
hybridizing the capture probe or the capture probe in the kit with the DNA library for capture and sequencing;
performing bioinformatics analysis on the sequencing result to obtain the sequencing fragment ratio corresponding to each heterozygous SNP locus;
calculating a genome abnormal index based on the sequencing fragment ratio corresponding to the heterozygous SNP locus;
and quantitatively evaluating the genome abnormality according to the genome abnormality index.
Preferably, the obtaining the ratio of the sequencing fragments corresponding to each heterozygous SNP site comprises:
acquiring the number of each allele of the heterozygous SNP locus and the total number of all alleles;
the ratio of each allele was calculated using the number of each allele and the total number of all alleles.
Preferably, the genomic abnormality index includes: LOH, TAI and LST, wherein LOH is the copy number of a secondary allele in a segment is 0, the copy number of a primary allele is not 0, and the length of the segment is more than 15M; TAI is initiated from telomere and does not cross the centromere, the fragment length is greater than 11M; the LST is a case where after deleting segments shorter than 3M, the lengths of two adjacent segments are both greater than 10M.
Preferably, the calculating of the genomic abnormality index based on the ratio of the sequencing fragments corresponding to the heterozygous SNP site comprises:
detecting heterozygous SNP sites located on the same chromosome arm, and classifying the adjacent heterozygous SNP sites into the same segment if the rank and the detection P value of the adjacent heterozygous SNP sites are greater than the threshold value, so as to realize the segmentation of the genome;
and obtaining the optimal tumor purity, ploidy and copy number information by adopting a probabilistic model parameter estimation method according to the depth and the sub-allele frequency of each segment, and calculating LOH, TAI and LST of the genome according to the information and the segment information.
In a third aspect, the present invention provides a capture probe for assessing genomic abnormalities, said probe being useful for capturing nucleotide fragments comprising a plurality of SNP sites as described in the first aspect.
In a fourth aspect, the present invention provides a kit for assessing genomic abnormalities, which comprises at least one dose of the probe of the third aspect.
In a fifth aspect, the invention provides a probe according to the third aspect or a kit according to the fourth aspect for use in assessing genomic abnormalities.
In a sixth aspect, the invention provides the use of a probe according to the third aspect or a kit according to the fourth aspect in the manufacture of a product for assessing genomic abnormalities.
The invention has the beneficial effects that: compared with the staining-based karyotype analysis, the application of the SNP locus in the evaluation of the genomic abnormality and the method for evaluating the genomic abnormality have higher precision; compared with the method for indirectly judging the genome abnormality by detecting BRCA mutation, more and more comprehensive genome abnormality conditions can be found; compared with digital karyotyping based on whole genome sequencing, the method can treat the genomic abnormality with unchanged chromosome structure, such as the chromosome deletion from the female parent and the double copy of the male parent chromosome; compared with the current common method (such as Myriad company) for detecting loss of heterozygosity (LOH) in the market, the selected locus is more suitable for Chinese people, and the evaluation result is more accurate.
Drawings
FIG. 1 is a diagram illustrating the distribution of abnormal scores of genomes according to the embodiment of the invention.
Detailed Description
In order to better understand the technical scheme, the technical scheme is described in detail in the following with reference to the attached drawings of the specification and specific embodiments.
"genomic abnormality" is understood in its broadest sense to mean any change in the genomic sequence, such as a single nucleotide mutation, a structural variation, a methylation modification of a particular region, and the like. The genomic abnormality as referred to in the present invention refers to genomic instability, that is, a phenomenon of genomic scarring.
Example one
The embodiment of the invention provides application of the SNP locus in evaluating genome abnormality or preparing a product for evaluating genome abnormality. Wherein, the SNP loci can be selected according to the following method:
based on Single Nucleotide Polymorphism (SNP) locus data of Chinese population, biallelic high polymorphism loci distributed on chromosomes as uniformly as possible are selected.
First, the population minimum allele frequencies of these loci were all above 0.05, distributed between 0.05 and 0.5. The density of sites on the genome is approximately 16.5/mega genome base so that abnormalities throughout the genome can be better assessed.
Secondly, in order to obtain relatively balanced data among sites, the content of cytosine (C) and guanine (G) in the genome region where the site is located is limited, such as the GC content of 300 nucleotides centered on the SNP site is required to be 40-60%.
Again, to rule out significant genotyping errors, the SNP site is required to comply with the haddi-weinberg equilibrium law. Meanwhile, in order to reduce the influence of population differentiation degree between different domains, the SNP site needs to satisfy a population differentiation index (FST) lower than 0.05.
Thirdly, in order to improve the detection effect, more than 500 cases of actual detection data of clinical samples are adopted to screen the sequencing depth and the sequencing stability of the sites.
Finally, 51263 double-allele high-polymorphism sites of Chinese population are obtained.
Example two
The embodiment of the invention provides a method for evaluating genome abnormality, which comprises the following steps:
selecting a plurality of SNP sites, wherein the selected SNP sites and the selection method thereof can refer to the method provided by the first embodiment;
constructing a capture probe or kit; wherein the capture probe can capture a nucleotide fragment containing a plurality of SNP sites as described in example one. The kit comprises at least one dose of the probe. The probe and the kit can be used for evaluating the genome abnormality and can also be used for preparing products for evaluating the genome abnormality.
Extracting DNA of a detection sample;
constructing a detection sample DNA library;
hybridizing the capture probe or the capture probe in the kit with the DNA library for capture and sequencing;
performing bioinformatics analysis on the sequencing result to obtain the sequencing fragment ratio corresponding to each heterozygous SNP locus;
calculating a genome abnormal index based on the sequencing fragment ratio corresponding to the heterozygous SNP locus;
And quantitatively evaluating the genome abnormality according to the genome abnormality index.
In the above methods, both the sample to be tested (e.g., solid tumor) and a comparable abnormal-free control sample (e.g., peripheral blood from a patient with solid tumor) can be treated. If there is no control sample, only the test sample may be treated.
The detection process comprises an experiment part and a bioinformatics analysis part, wherein the experiment part can be implemented by adopting the following steps:
1. sample collection and reception
a. Fresh blood sample: the detection standard is EDTA anticoagulation blood 2 ml;
b. paraffin section sample: the detection standard is 5 μm thick and larger than 1cm 2 At least 6 pieces of surgical tissue and at least 10 pieces of puncture tissue;
c. fresh tissue samples: the tissues were placed in 10% formalin storage tubes and RNAlater storage tubes, respectively, for examination, with 1 tissue per tube being about the size of soybeans.
2. Tumor content assessment
The tumor tissue needs to be evaluated for the tumor content, and the qualified standard of the tumor content is more than or equal to 20 percent. If the tumor content is more than or equal to 10% and less than 20%, the risk detection can be carried out, and if the tumor content is less than 10%, the detection is stopped.
3. Sample DNA extraction and quality control
The DNA in the sample can be obtained using a DNA extraction kit (e.g., a DNA extraction kit dedicated to formalin-fixed paraffin-embedded samples, a whole blood DNA extraction kit) for the corresponding sample type.
The quality inspection of the sample DNA needs to meet the following requirements:
a. the total amount of DNA detected by the Qubit in blood or fresh tissue is more than or equal to 200ng, and the main band of the DNA detected by gel electrophoresis is more than or equal to 10 Kbp.
FFPE/wax block requires a total amount of DNA to satisfy a minimum initial pool building amount at a time.
4. Library construction
The library is obtained by DNA fragmentation, end repair and adenine (A) addition, adaptor fragment ligation, amplification steps. The concentration of the constructed library is more than or equal to 0.5 ng/mu l.
5. And (3) hybridizing the capture probe or the capture probe in the kit with the DNA library for capture. And mixing the DNA library with the synthesized site capture probe, performing a hybridization capture experiment, and after the capture probe and the library are fully mixed, performing elution and purification steps to obtain a final operable sequencing library.
6. Sequencing on machine
Novaseq6000 is adopted as a sequencing platform, the machine-out sequencing quantity of the tumor tissue is 6G, and the machine-out sequencing quantity of the control sample is 2G.
The specific operation methods of all the steps are the same as those in the prior art, and are not described herein again.
The bioinformatics analysis section may be implemented by the following steps:
1. and the data analyst starts data analysis after receiving the data offline notification of the data manager.
2. And extracting the item number, the corresponding subject screening number and the corresponding data path according to a data docking table provided by a data administrator, and writing the item number, the corresponding subject screening number and the corresponding data path into a standard input format required by an automatic analysis process.
3. Starting a data analysis process, wherein software used in the process comprises the following steps: fastp (version 0.20.0), bwa (version 0.7.17-r 1198-dirty), samtools (version 1.9), gatk (version 4.2.2.0), bendaols (version v 2.30.0). The data analysis process is generally completed within 5-8 hours, and after the data analysis process is completed, the student needs to check the analysis and quality control result, and the quality control standard is shown in table 1. If the quality control is passed, a report analysis record is filled. If the analysis is interrupted or the quality control fails, the processing is required to be carried out in an exception handling mode.
Figure 78579DEST_PATH_IMAGE001
Note: table 1 shows the quality control standard of sequencing data. The sequence alignment quality of the control sample and the detection sample is higher than that of Q30, and the sequence alignment rate is higher than 90%. The average sequencing depth of the control sample is at least 50X, and the average sequencing depth of the detection sample is at least 150X.
4. Exception handling: for example, the analysis interruption is first confirmed. If the analysis is interrupted due to external reasons, such as power failure of an external computer room, hardware failure and the like, analysis can be performed again according to the analysis flow after the failure is eliminated and the intermediate folder is renamed and analyzed. The original folder name is weighed and named as "original folder name-analysis times". If the quality control fails, a data manager needs to be contacted for carrying out additional testing or retesting, and the analysis is restarted.
5. A report is generated.
The specific operation methods of all the steps are the same as those in the prior art, and are not described herein again.
And performing bioinformatics analysis on the sequencing result, comparing the sequencing fragments to a human genome, extracting the sequencing fragment information of 51263 sites, and recording the sequencing fragment ratio corresponding to each site. And selecting the heterozygous SNP locus for calculating the subsequent heterozygous deletion LOH, telomere imbalance TAI and large fragment displacement LST. Assuming that SNP site i has two alleles A and B, the number of sequencing fragments corresponding to A is N, the number of sequencing fragments corresponding to B is M, calculating the ratio p of the sequencing fragments corresponding to A i = N/(N + M), and the sequencing fragment ratio q corresponding to B i = M/(N + M). Thus, data information of each heterozygous SNP site of the sample to be detected and the control sample is obtained. Then, sequencing is carried out according to the correspondence of the SNP sitesSegmenting the genome according to the fragment ratio and the corresponding sequencing depth, specifically, detecting the heterozygous SNP sites located on the same chromosome arm, and classifying the adjacent heterozygous SNP sites into the same segment if the rank sum detection P value of the adjacent heterozygous SNP sites is greater than a threshold (such as 0.001, 0.01, 0.05, 0.1) so as to segment the genome. And then, according to the information such as the depth and the sub-allele frequency of each segment, estimating the optimal information such as tumor purity, ploidy, copy number and the like by adopting a probabilistic model parameter estimation method. Then, based on the above segmentation information and the optimal tumor purity, ploidy, and copy number, LOH, TAI, and LST of the genome are calculated. Where LOH is defined as the copy number of the minor allele in the segment being 0, the copy number of the major allele not being 0, and the length of the segment being greater than 15M. TAI is defined as starting from the telomere and not crossing the centromere, with a fragment length greater than 11M. LST is defined as the case where after deleting segments shorter than 3M, the lengths of both adjacent segments are greater than 10M. Finally, counting the number of LOH, TAI and LST in the genome, and calculating the HRD score (HRDscore) according to the following formula:
HRD (homologous recombination defect) score = LOH number + TAI number + LST number, and genomic abnormalities are quantitatively evaluated according to HRD score.
The effects of the embodiments of the present invention were evaluated by the following methods:
samples were classified by whether or not they underwent biallelic mutation in BRCA1 or BRCA2, and then the distribution of the genomic abnormality assessment scores for samples that did not underwent BRCA1 or BRCA2 biallelic mutation was compared to the genomic abnormality assessment scores for samples that underwent BRCA1 or BRCA2 biallelic mutation. The present example tests 624 tumor samples from ovarian cancer patients and control peripheral blood samples. The samples are subjected to mutation detection of BRCA1 and BRCA2, and the result shows that the 122 case samples have germ line or somatic cell BRCA1/2 pathogenic or possibly pathogenic mutation. According to the result, the case samples are divided into two groups, and the sequencing data of the samples are obtained by the steps of DNA extraction, library building, hybridization capture, computer sequencing and the like of the samples. Then, by performing confidence analysis on the sequencing data, after the genome abnormality score of the detected tumor is obtained, the distribution of the genome abnormality evaluation score is obtained as shown in fig. 1.
FIG. 1 shows the distribution of abnormal scores of genomes of 624 ovarian cancer patients. In the above, negative on the abscissa represents 502 samples in which no biallelic mutation of BRCA1 or BRCA2 occurred, "BRCA 1_ pos" represents a sample in which biallelic mutation of BRCA1 occurred, "BRCA 2_ pos" represents a sample in which biallelic mutation of BRCA2 occurred. The ordinate represents the genomic abnormality score (HRDscore) and the width represents the number of samples for a particular score. As can be seen from fig. 1, the samples with BRCA1 or BRCA2 pathogenic or possibly pathogenic mutations had significantly higher overall abnormal score distribution, while the abnormal scores of the samples without genetic mutations were overall lower, but the abnormal scores of the samples with a certain proportion were similar to those of the mutated samples. For this sample, PARPi can also be used to guide drug administration.
While preferred embodiments of the present invention have been described, additional variations and modifications in those embodiments may occur to those skilled in the art once they learn of the basic inventive concepts. Therefore, it is intended that the appended claims be interpreted as including preferred embodiments and all such alterations and modifications as fall within the scope of the invention. It will be apparent to those skilled in the art that various changes and modifications may be made in the present invention without departing from the spirit and scope of the invention. Thus, if such modifications and variations of the present invention fall within the scope of the claims of the present invention and their equivalents, the present invention is also intended to include such modifications and variations.

Claims (6)

1. The application of a plurality of SNP loci in preparing products for evaluating genome abnormality is characterized in that the SNP loci are biallelic high-polymorphism loci which are approximately and uniformly distributed on a chromosome, and the group minimum allele frequency of each SNP locus is uniformly distributed between 0.05 and 0.5; the density of each SNP site on the genome is 16.5/mega genome base; the GC content of 250-350 nucleotides taking each SNP locus as the center is 40-60 percent; each SNP site accords with the Hardy-Winberg equilibrium law and simultaneously satisfies that the group differentiation coefficient is lower than 0.05; the position of the SNP locus on chromosome 1 comprises: 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The positions of the SNP loci on chromosome 2 include: 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97,241994130,242062779,242099322,242134052,242167146,242214126,242261864,242355406,242396852,242430994,242473262,242509828,242535751,242605809,242651996,242699935,242737930,242776689,242842090,242872883,242909723,242937084,242963185,243001279,243052200, respectively;
The positions of the SNP loci on chromosome 3 include: 85398,122620,159349,192951,229772,265878,293670,357478,386858,420563,452169,482015,556186,591835,629079,641644,652407,664057,705014,742023,836863,957683,1034572,1067554,1106129,1132600,1167565,1199147,1233707,1299234,1325850,1350749,1382358,1419610,1455503,1486855,1514387,1547126,1580245,1615187,1643255,1668078,1698843,1721794,1753741,1788100,1819199,1849094,1879580,1928857,2008318,2037106,2076967,2115036,2152464,2195083,2231506,2267266,2308873,2375705,2408172,2439658,2482565,2519956,2607296,2716585,2747150,2776983,2811642,2835225,2864293,2902330,2937973,2974206,3008424,3038804,3071341,3104262,3188016,3278581,3308432,3339135,3377328,3444169,3490110,3518222,3554473,3588016,3630813,3696585,3731473,3766921,3793058,3825601,3860052,3903288,3947388,3979971,4010819,4043726,4084288,4127195,4163133,4201718,4242874,4321820,4361643,4429829,4468598,4509643,4581685,4622135,4657422,4697557,4766787,4806844,4893093,4929937,4969848,5004589,5081285,5113533,5148635,5183598,5233579,5273967,5305951,5343227,5402383,5434536,5474369,5510739,5541046,5580188,5608375,5681689,5715824,5751620,5788086,5840858,5909068,6007536,6040777,6089000,6120412,6157479,6191843,6226057,6258617,6328299,6362888,6407442,6446710,6488390,6526115,6572131,6618824,6651923,6723586,6752063,6787060,6825247,6873635,6963502,7123988,7158766,7199400,7243510,7291712,7335496,7370916,7400815,7433503,7476420,7509460,7550214,7591829,7631501,7676844,7708970,7787065,7823658,7863402,7895977,7958860,8029455,8076451,8159847,8192385,8233351,8274556,8319322,8364898,8416380,8453660,8544503,8589558,8632542,8670589,8707343,8729079,8771776,8805897,8915430,8954570,8991035,9033989,9072370,9112746,9203491,9254177,9303124,9328411,9378454,9430868,9486810,9543549,9634373,9680870,9742107,9794503,9880082,9924837,9962157,10042113,10079255,10106366,10183328,10248072,10321229,10362003,10406335,10442912,10492479,10665546,10758284,10796810,10842708,10887446,10931851,10977742,11061814,11104896,11151790,11197276,11236121,11284950,11336966,11387847,11481794,11522932,11604444,11640752,11673717,11703193,11743393,11819597,11859953,11933184,11960066,11992711,12079287,12168317,12216142,12259545,12297990,12345208,12395792,12443530,12484928,12525141,12565822,12605189,12638071,12715167,12757726,12796495,12831860,12906429,12943152,12994451,13042625,13081885,13121790,13162185,13202733,13240008,13280980,13312705,13357220,13398100,13442892,13479822,13598025,13635107,13673043,13740341,13778888,13823342,13943704,14003540,14063880,14117495,14156704,14251932,14290362,14324303,14362702,14398465,14436494,14519597,14566562,14608720,14651163,14696529,14737076,14782794,14831822,14878427,14953440,15003380,15102538,15150718,15182917,15278438,15325053,15361469,15402142,15445458,15484219,15520004,15570207,15661619,15701981,15798096,15849743,15901288,15941590,15990854,16029000,16067395,16113962,16190032,16315846,16359747,16459007,16589527,16627980,16753274,16797646,16841071,16888997,16936880,16986805,17092437,17149682,17189255,17297027,17345868,17455212,17513650,17703519,17813559,17860583,18017998,18082293,18137450,18191413,18247284,18299818,18404672,18457022,18519543,18570342,18617351,18658743,18743561,18780545,18861222,18913178,18965272,19024741,19148454,19258733,19313473,19429040,19500998,19572906,19629305,19688343,19745124,19793081,19885662,19930695,19971222,20007355,20047314,20120548,20158447,20195754,20236385,20275739,20321893,20359744,20401600,20445437,20487378,20519918,20570352,20608960,20700544,20741611,20776569,20821600,20868543,20908350,20954311,21001549,21081292,21118190,21164127,21198099,21244087,21292640,21336127,21373177,21422263,21459354,21490154,21525924,21620699,21653380,21690066,21729643,21761052,21793016,21820206,21852247,21935869,21962770,21988749,22015139,22048052,22078057,22110830,22139124,22170312,22197207,22231231,22269188,22303740,22341338,22383570,22421263,22459532,22501301,22544898,22608641,22644689,22693474,22725948,22773519,22825701,22879291,22918704,22957240,23005640,23051547,23113619,23152463,23224990,23271602,23315895,23367021,23414207,23511224,23646642,23691547,23732047,23769077,23805036,23848336,23970695,24004522,24048679,24099794,24152386,24192427,24231351,24270401,24304085,24350299,24443213,24494308,24534311,24632808,24670695,24711945,24747070,24782729,24818629,24857987,24904344,24939147,24975241,25010579,25037722,25074918,25115413,25150172,25184389,25214273,25249631,25288934,25327020,25364777,25403207,25435001,25475575,25513249,25549386,25586638,25626640,25728744,25784644,25838680,25890495,25939205,25992832,26042744,26098681,26150748,26205926,26250572,26303642,26363627,26421172,26509415,26544725,26575139,26618499,26655743,26693915,26743491,26786159,26826444,26874715,26961874,26994882,27046234,27079935,27113347,27148558,27213170,27254843,27299830,27343549,27433911,27487386,27527307,27569582,27616415,27687903,27728597,27821328,27866220,27905669,27943615,27986865,28027538,28071840,28117982,28158825,28211885,28259604,28317010,28374464,28435177,28506980,28572040,28633671,28801319,28843618,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respectively;
The positions of the SNP loci on chromosome 4 include: 36457,56076,80367,124902,182332,226937,272579,320897,361651,407393,452065,499439,535739,583034,628315,665779,739141,769298,810507,883039,920972,970377,1011417,1049875,1114351,1161798,1240810,1278004,1306886,1373622,1406658,1496783,1537914,1567158,1605843,1634784,1664874,1780419,1811328,1935055,1998120,2054055,2106765,2161429,2194374,2244674,2288238,2366664,2398055,2423366,2456802,2504195,2595468,2645478,2741679,2857374,2908782,2948514,2991526,3028401,3068482,3164628,3220761,3261763,3298395,3340889,3382389,3434167,3473650,3494228,3517485,3549038,3571181,3581893,3593301,3602070,3610486,3625606,3634306,3656013,3683470,3714836,3746318,3782455,3812631,3833120,3892445,3925213,3952815,3972887,4002998,4036180,4057717,4076723,4111202,4137752,4160310,4183878,4207215,4228738,4250241,4277847,4305537,4335824,4366950,4440539,4495118,4543407,4582183,4627958,4666770,4701962,4741418,4786670,4860254,4889621,4932445,4965462,5003283,5037445,5081995,5108497,5144868,5180055,5212544,5251594,5282794,5310453,5344472,5378053,5410837,5442765,5474386,5525897,5562539,5604800,5636113,5667134,5706091,5762623,5799547,5858579,5930920,6023171,6056325,6090641,6128624,6161577,6197404,6271416,6356557,6389642,6416861,6452814,6484168,6527252,6603943,6637273,6705590,6738935,6767566,6818015,6869307,6908751,6949223,6987446,7073187,7109184,7140918,7169275,7203849,7231418,7263980,7304496,7330321,7363331,7392523,7415699,7440604,7468947,7487800,7511012,7537063,7571761,7610416,7666722,7725585,7756195,7782804,7840332,7868217,7896213,7922096,7955294,7990930,8029018,8097789,8136641,8177203,8215226,8246502,8312738,8338034,8372856,8403533,8451179,8494089,8559688,8588179,8610899,8644405,8682821,8715672,8933168,9034510,9111280,9184457,9419658,9446609,9480019,9515883,9537431,9564484,9585071,9606018,9636355,9702790,9733115,9766886,9800679,9843356,9920086,9954238,9982917,10017979,10052817,10089253,10121012,10136685,10152935,10176594,10198514,10231237,10260765,10290420,10320891,10355396,10391902,10437334,10480591,10514681,10599205,10642159,10706970,10737954,10997737,11037998,11082149,11124523,11243343,11280398,11318311,11368670,11414198,11450699,11480557,11516449,11546396,11588899,11620694,11665013,11706820,11746643,11769076,11813105,11850401,11884465,11919586,11950395,11989859,12035048,12082491,12112707,12193889,12275587,12310722,12358940,12409447,12465168,12512865,12553096,12588094,12624701,12653988,12683297,12727586,12765282,12799832,12843654,12888358,12929066,12967195,13009049,13096420,13141039,13193386,13237029,13293417,13336573,13391329,13449807,13504752,13554557,13606027,13661643,13707225,13785739,13830615,13915104,14007710,14050263,14091440,14130567,14168299,14206434,14363148,14395094,14476568,14509817,14534626,14566932,14604890,14691717,14728549,14771119,14811600,14840518,14874138,14956607,15007988,15063390,15114305,15159192,15204853,15245140,15293023,15334214,15388838,15490752,15555221,15615479,15660184,15824974,15874537,15915388,15961555,16000542,16041619,16088567,16132084,16169755,16217627,16265834,16307516,16353893,16403682,16444413,16493698,16542294,16592117,16641382,16691200,16736331,16778299,16824435,16872076,16914832,16961656,17022015,17062007,17105777,17139437,17228148,17273023,17308473,17346374,17425937,17460970,17489883,17530699,17563687,17604802,17672465,17706071,17754729,17808337,17876943,17939302,18046636,18096948,18148869,18199611,18252106,18290930,18340461,18394023,18442406,18487049,18534169,18632463,18670863,18754700,18789221,18842624,18895094,18951799,19007280,19058515,19159497,19259080,19300189,19348177,19392182,19463717,19504786,19543063,19588900,19632142,19681035,19732689,19782712,19899705,19950098,20006151,20058664,20083052,20119727,20156709,20197183,20240093,20286490,20332458,20391615,20485321,20579306,20634072,20685544,20732701,20775383,20853948,20898558,20940550,20983806,21027322,21064253,21104021,21137001,21178999,21217985,21293490,21333298,21410659,21455256,21487844,21517194,21557180,21596543,21640489,21686957,21786688,21818459,21857425,21940697,21992543,22047433,22089812,22189941,22243808,22290611,22336096,22384063,22425837,22468621,22502130,22570233,22731822,22775690,22816662,22873033,22933965,22989505,23093028,23154778,23246187,23328370,23381513,23425588,23469584,23516403,23561069,23597396,23631652,23674005,23750569,23789477,23830741,23875589,23956205,24000544,24041628,24081446,24120953,24157323,24243483,24280371,24324927,24415092,24549927,24600388,24640911,24676440,24718497,24760535,24797566,24844929,24883062,24927682,25045341,25080036,25122890,25176277,25228583,25274171,25357164,25406189,25439633,25582496,25648141,25687153,25718984,25751278,25794583,25838901,25888370,25938806,26014228,26048141,26094992,26144084,26188992,26230326,26275336,26316816,26356092,26409537,26452301,26488853,26523592,26567378,26753223,26814210,26911129,27079874,27172472,27208505,27250649,27294111,27525746,27564839,27604705,27643547,27685167,27752434,27785567,27867912,27909347,27956188,27993916,28038705,28079899,28151913,28193573,28259975,28304630,283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respectively;
The positions of the SNP loci on chromosome 5 include: 28591,80330,111986,158000,185418,213460,243756,265541,326854,361861,400457,428044,489071,514600,549119,580051,620052,642061,668006,691777,718300,751989,779885,816751,850943,883311,998691,1029127,1048207,1096469,1136717,1170927,1199812,1228362,1259060,1280848,1306521,1370122,1397859,1475309,1512207,1622797,1654572,1686711,1723309,1759385,1794921,1833008,1858834,1889208,1926028,1952539,1992952,2020905,2058886,2087489,2149254,2177986,2221147,2258634,2288471,2317351,2346106,2371742,2401963,2446514,2512701,2540504,2573863,2605035,2675607,2783839,2860637,2897302,2937343,2977667,3014197,3040091,3067438,3089029,3151352,3179203,3215014,3244395,3277083,3309567,3339548,3373293,3407131,3481994,3514932,3549239,3584368,3622205,3646322,3709754,3739311,3821134,3862010,3905547,3947720,3985247,4056903,4136972,4176952,4214994,4254667,4283895,4317544,4363113,4408823,4451646,4503514,4547930,4648933,4689313,4782636,4826903,4870565,4905516,4942141,4975491,5046134,5082787,5119935,5151014,5192434,5226529,5256184,5291003,5321699,5361531,5406439,5452271,5509703,5551563,5621227,5658048,5706221,5742679,5775621,5806664,5835572,5867266,5938416,6014092,6050705,6096958,6177662,6215343,6252374,6300903,6337964,6376901,6418293,6498898,6532922,6562251,6595332,6624395,6664544,6792706,6913974,6993963,7041391,7098789,7141602,7186765,7263115,7303115,7337663,7380105,7435782,7483970,7529360,7619398,7671849,7755900,7798723,7841044,7883344,7924786,7992118,8018341,8037217,8106426,8136694,8261713,8339294,8381466,8498478,8530645,8561056,8594190,8635455,8674114,8714999,8784956,8824582,8871253,8915125,8948201,8987082,9038128,9083548,9127005,9162608,9228330,9272445,9315546,9356174,9396929,9441835,9485592,9531592,9562847,9650968,9701222,9847182,9894252,9931139,9971938,10002461,10036432,10083440,10141280,10189940,10308303,10365943,10435684,10476898,10515515,10553430,10591926,10633559,10666141,10745313,10831721,10874972,10910357,10948006,10984610,11029448,11076293,11112920,11148358,11236470,11289232,11324556,11365226,11403115,11446860,11484326,11522405,11566327,11614029,11657823,11707597,11746670,11825737,11876618,11918305,11960579,12009331,12050820,12099362,12141669,12188357,12233805,12336315,12384283,12430936,12531485,12623469,12674760,12716629,12826922,12914597,12994384,13132480,13211172,13252521,13295206,13378486,13423083,13467834,13517073,13614012,13663328,13711606,13813566,13881117,13923049,13971438,14006146,14040816,14078947,14119796,14175415,14218755,14308893,14350622,14396501,14443901,14491119,14579179,14629808,14667647,14722254,14763707,14850760,14941233,14987807,15038608,15088089,15129378,15179136,15233673,15286665,15330414,15491272,15552349,15610764,15655657,15706868,15809088,15869199,15920361,15972190,16023473,16071465,16113511,16160122,16209712,16259288,16305782,16362819,16410338,16501407,16574900,16619142,16653410,16724163,16767999,16829117,16861957,16895460,16999059,17058914,17086137,17194288,17237379,17283714,17333059,17374010,17418015,17460157,17499656,17517363,17624715,17645821,17696204,17745762,17789202,17820596,17863867,17905745,17957181,18017404,18057933,18137215,18179172,18218841,18296992,18332372,18362232,18403268,18435021,18466629,18508723,18552406,18655256,18692076,18738697,18793012,18850367,18900292,18948922,18987340,19026995,19072206,19113940,19156316,19199034,19247982,19302666,19342039,19380639,19419011,19457951,19495246,19549254,19601146,19652053,19700778,19742587,19797686,19849674,19897952,19949165,19988159,20038980,20241644,20286161,20329201,20372972,20416305,20493759,20531779,20564766,20608837,20719200,20810186,20862531,20916354,20970049,21013014,21134979,21188923,21235990,21284079,21360864,21458784,21513500,21532971,21560130,21582016,21774281,21823307,21864751,21908707,22004398,22053951,22100944,22154317,22267870,22311885,22412622,22453948,22501529,22612031,22670207,22715696,22760514,22867148,22922432,22971508,23052940,23091379,23134126,23178836,23225207,23269862,23302487,23343169,23377407,23420972,23475602,23544386,23591768,23623268,23656668,23692408,23729125,23761578,23805068,23854490,23885467,23940902,24048548,24093038,24126392,24201989,24250646,24292923,24330283,24382600,24488981,24520631,24588115,24635537,24684126,24736053,24783811,24830442,24873222,25014518,25070363,25119167,25173414,25293922,25404676,25491096,25583987,25633314,25687581,25727665,25767506,25799266,25870090,25899331,25932561,26004186,26045956,26091309,26133448,26174975,26260788,26304906,26350979,26389262,26436687,26491852,26538201,26576132,26612915,26654061,26701742,26747389,26789045,26816907,26846512,26887490,26926690,26960169,27064324,27126724,27173004,27222745,27280987,27332476,27386390,27480333,27525129,27569575,27613137,27762814,27872626,27913609,27952844,28000781,28051459,28107414,28155164,28204574,28249141,28293697,28342019,28383144,28434019,28526048,28579311,28635141,28684634,28729582,28788615,28927390,28964829,29007332,29044907,29079633,29128628,29177840,29212515,29325101,29363706,29405536,29445756,29475912,29508123,29551016,29589776,29623416,2965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respectively;
The positions of the SNP loci on chromosome 6 include: 151967,211215,243497,285984,321528,354101,373017,407496,444600,462929,494045,528568,611780,652056,686970,723959,761367,796433,830957,867209,923900,963300,1002406,1036815,1068909,1108340,1144302,1188100,1217908,1250317,1285521,1319106,1395427,1434925,1463535,1500664,1534344,1567011,1605258,1648892,1682466,1715849,1791818,1891709,1930663,2060072,2166230,2214632,2262794,2325562,2369492,2407481,2490391,2521754,2552939,2589808,2628943,2668071,2704475,2737204,2777344,2815277,2853342,2880480,2919303,2953560,3041557,3077575,3107282,3144826,3179222,3222210,3256473,3279127,3308312,3381759,3423587,3462885,3502666,3666833,3716550,3749436,3777025,3821627,3862273,3901224,3944586,3985834,4028023,4108360,4149025,4190126,4271667,4315480,4368431,4402324,4428761,4466210,4496219,4537791,4574440,4612410,4653371,4683015,4714923,4782412,4820277,4870030,4905947,4938982,4974088,5003987,5079237,5148778,5181660,5229259,5265797,5304008,5351524,5387602,5420642,5453893,5489864,5530595,5647113,5688576,5731236,5780846,5825331,5863211,5909813,5958001,5999332,6065950,6103709,6144552,6181768,6232032,6278028,6384319,6422355,6465553,6514123,6549127,6581897,6606050,6718461,6745234,6780016,6819029,6849713,6888560,6922016,6950098,7012032,7085512,7232996,7270881,7301671,7328267,7422329,7444241,7517509,7554466,7642748,7683278,7730254,7776336,7816954,7856850,7898529,7980400,8012812,8041545,8077422,8166567,8204413,8248234,8284191,8352518,8386086,8459292,8487369,8528008,8563498,8598496,8637318,8679579,8784507,8836128,8920969,8964533,9010731,9049101,9084400,9130600,9184857,9277213,9323458,9375620,9426953,9482271,9529203,9575673,9637645,9706545,9773802,9822969,9960805,10006058,10090687,10131177,10174652,10218322,10259823,10332713,10416004,10459311,10482201,10503336,10562475,10577388,10706503,10740422,10786720,10836938,10881404,10922715,11011100,11063362,11196923,11281742,11329235,11414705,11465141,11537014,11586435,11630685,11669514,11707941,11741649,11788703,11832737,11881875,11918687,11954693,11988024,12035652,12076676,12125541,12170951,12211721,12245559,12288769,12335338,12375643,12429862,12471888,12517124,12558084,12645050,12681799,12835015,12874870,12922022,12963708,13014227,13116222,13153314,13192799,13231251,13293570,13329355,13362716,13398846,13432272,13513622,13546503,13602013,13723128,13764846,13799494,13843846,13902302,13957851,14003405,14040139,14077382,14113617,14150150,14203872,14255473,14311039,14354347,14501602,14583270,14618307,14656963,14738582,14816864,14865069,14908323,14947558,15029972,15145279,15182037,15222059,15259168,15300953,15348722,15435269,15476700,15519017,15629223,15683947,15723361,15763063,15804525,15847048,15886281,15926822,15964299,16006213,16050501,16089389,16140197,16185967,16221045,16241594,16389578,16424956,16520249,16565472,16601127,16639118,16681323,16720087,16772452,16819151,16915370,16957479,16999063,17040313,17091097,17141776,17192383,17245424,17289545,17334641,17376791,17417376,17456826,17498937,17542668,17587301,17669727,17821166,17860951,17906329,17954426,18005863,18030179,18076141,18112715,18145927,18219375,18307976,18387064,18450920,18517922,18593042,18634813,18676802,18713818,18797392,18882998,19021288,19077434,19175191,19248973,19291506,19331923,19374999,19455796,19494175,19528592,19569186,19611120,19653252,19738236,19784579,19809033,19854105,19931686,19967069,20096612,20140016,20175484,20212606,20252093,20418329,20470930,20520353,20598865,20635026,20670293,20714466,20799198,20841292,20937984,21131143,21175492,21218478,21303195,21337490,21380141,21426960,21468829,21515018,21568585,21621012,21739773,21780724,21855730,21897661,22017317,22090538,22129677,22173648,22209151,22243965,22374911,22408330,22450262,22491435,22527391,22573546,22655242,22697499,22737762,22787601,22834310,22876526,22913339,22956022,23002162,23041376,23091400,23144229,23188059,23229513,23274977,23309017,23348187,23388486,23418298,23453200,23500598,23547686,23584830,23616717,23649127,23678135,23706272,23735498,23760775,23787317,23823804,23857033,23925051,23957912,23992877,24033828,24077431,24124484,24167478,24236574,24280881,24318579,24401654,24433643,24457838,24484419,24515688,24555220,24596843,24719058,24846863,24940849,24971403,25005966,25045904,25084858,25165141,25247680,25312996,25340870,25376467,25406680,25441053,25490370,25531925,25585640,25631179,25669338,25749554,25789021,25884785,25929404,25967927,26021544,26062398,26104632,26142823,26190863,26228043,26277411,26320364,26366428,26402676,26451553,26499179,26555484,26599855,26742983,26798697,26859533,26901604,26955178,27003483,27101891,27152008,27187379,27276171,27331782,27423248,27471511,27516769,27569607,27621255,27812807,27861346,27984907,28038251,28096196,28197469,28254770,28308671,28395437,28442333,28482917,28611154,28688843,28714778,28737295,28761471,28782734,28815952,28875686,28902608,28938353,28973712,29010587,29052301,29093327,29132271,29164873,29210724,29257320,29299503,29338563,29363697,29385415,29443889,29477783,29504206,29527621,29564486,29591469,29621536,29643877,29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6695,166920113,166953012,166993009,167032361,167071948,167148204,167183881,167213777,167245665,167273761,167318323,167392527,167424293,167456036,167505548,167544464,167584647,167620431,167641005,167674303,167691342,167714737,167742636,167776834,167811787,167844197,168093726,168198522,168274042,168326684,168391985,168416272,168445020,168504184,168534170,168557632,168645267,168678889,168706362,168738643,168774656,168799631,168834662,168883406,168915660,168944930,168973265,168995544,169013720,169035322,169060658,169097222,169131335,169169092,169202643,169233339,169247748,169266997,169293930,169313513,169334697,169365193,169395027,169434020,169471271,169508634,169541179,169576662,169607718,169636624,169712830,169752931,169867207,169916583,169958850,170025492,170065117,170173967,170208403,170249889,170364566,170398825,170428032,170455906,170496430,170529253,170553895,170579994,170625298,170664813,170703743,170727677,170758245,170778521,170845354,170888363,171009273;
The positions of the SNP loci on chromosome 7 include: 63018,96312,117442,143945,172014,199624,220023,341524,511617,594686,686134,730834,828626,904368,933749,954862,977429,1017698,1049123,1072146,1100931,1132685,1157795,1189279,1210688,1242328,1275578,1310386,1334533,1366777,1410019,1457450,1495283,1570126,1610365,1652801,1691210,1792413,1852166,1888758,1918941,1944205,1975176,2008725,2048017,2124355,2200973,2240657,2280845,2315950,2403128,2430624,2473125,2512252,2546631,2585570,2617042,2644589,2673288,2742336,2764724,2836836,2874835,2938109,2966869,3001173,3033975,3094488,3127660,3155668,3185260,3242371,3272227,3334836,3359708,3387838,3420443,3453333,3519885,3555462,3629521,3662146,3754653,3791115,3821953,3888321,3914875,3950836,4026009,4060005,4086123,4117436,4146288,4178823,4210874,4238412,4266583,4303279,4331707,4367133,4398657,4425837,4451320,4513330,4539982,4575849,4605654,4657654,4744796,4777207,4810712,4842577,4939038,4977659,5014519,5053287,5095577,5193946,5288168,5321113,5351444,5424636,5470363,5500145,5536379,5568863,5605445,5640871,5681903,5725443,5770400,5868561,5897906,5996104,6045597,6083951,6218003,6262355,6305817,6347041,6379537,6440883,6470206,6503384,6545369,6593496,6674724,6710094,6720384,6760203,6857441,6887323,6911082,6944645,6974952,6996353,7015797,7035605,7070743,7102584,7128515,7161793,7205854,7242686,7269777,7309885,7343138,7377368,7408659,7446846,7487308,7533479,7583953,7694722,7732347,7771121,7806815,7844340,7875856,7909659,7946590,7988650,8075115,8116836,8154136,8189629,8225224,8262922,8309275,8350404,8391115,8436060,8479629,8520389,8558959,8600498,8639678,8674306,8699560,8732406,8823447,8895484,8971784,8995414,9030356,9087523,9116799,9147011,9179684,9212596,9251214,9292876,9329824,9374548,9423414,9473970,9515348,9553037,9591611,9625115,9651917,9689761,9719759,9809503,9876688,9917581,9958144,9995571,10032228,10070089,10141996,10178822,10222749,10293191,10368770,10404393,10449020,10516005,10552259,10592286,10629615,10673337,10725451,10780738,10831607,10873865,10948631,10987457,11031114,11072214,11115578,11163459,11208989,11241635,11281957,11316527,11343074,11379953,11422942,11472736,11523249,11559288,11590583,11618675,11665971,11750617,11786624,11822682,11862342,11906401,11932615,11974451,12007576,12037234,12070560,12102313,12133937,12171723,12200287,12229796,12260546,12290724,12323936,12351245,12377937,12407582,12482517,12514636,12543622,12583153,12616242,12656390,12695442,12761698,12785780,12825805,12900316,12934776,12963866,13010649,13049523,13128696,13163517,13196721,13236232,13271297,13304611,13336929,13378131,13421817,13466283,13508540,13547757,13582614,13661045,13692529,13798406,13836721,13886700,13919741,13958662,13997159,14030119,14110358,14150643,14196943,14238703,14276766,14306522,14345939,14395580,14440441,14482710,14557048,14599259,14641395,14685825,14729087,14808055,14843912,14884744,14922349,14996167,15033129,15065798,15107479,15139814,15179443,15225415,15260042,15304266,15342244,15377318,15407982,15436505,15473921,15509221,15551301,15600816,15635022,15668307,15718461,15760654,15803580,15853046,15892633,15926770,15964754,16008390,16049458,16086674,16126723,16170530,16218545,16263161,16308329,16349864,16386034,16423819,16455330,16502332,16538967,16577376,16624693,16661694,16706051,16747711,16777333,16809170,16842760,16877706,16908741,16942661,16977505,17012944,17053030,17090223,17129241,17183806,17229862,17285635,17357630,17468811,17504506,17545170,17574553,17610758,17642946,17679434,17711759,17743563,17814607,17928480,17978343,18058852,18161620,18306410,18350296,18402849,18449665,18497011,18552373,18605487,18647876,18697666,18748952,18792116,18828964,18864122,18912137,18950118,19000113,19046946,19089438,19137857,19177639,19219778,19317754,19362075,19436443,19483054,19522027,19546810,19590347,19622050,19657122,19697067,19746541,19788301,19865278,19903503,19934505,19969897,20003753,20047875,20092407,20218520,20263578,20301688,20336810,20384620,20472512,20509672,20549389,20647703,20687181,20716213,20755114,20910451,20967325,21015161,21061980,21147557,21188774,21237468,21278141,21355243,21397981,21441078,21482567,21519608,21563052,21595155,21633505,21670593,21708050,21775076,21807773,21838330,21868394,21902986,21938469,22012548,22046080,22077458,22119972,22155760,22199634,22252165,22349769,22392027,22426826,22465557,22501109,22539421,22589911,22635725,22702016,22745623,22821881,22857589,22889410,22923649,23025891,23072077,23117765,23165119,23205853,23251746,23294648,23334502,23389444,23484260,23532235,23582052,23628380,23730246,23821784,23859374,23945976,23989900,24071397,24159020,24197906,24276803,24308281,24380444,24417090,24452713,24495798,24582398,24634797,24682520,24726752,24763467,24807405,24858444,24904868,25033198,25078712,25243976,25322653,25363617,25445040,25475585,25515926,25562381,25602216,25637958,25696093,25739360,25784462,25828569,25878124,25978571,26024687,26079330,26125625,26171823,26222973,26261143,26315472,26358318,26391892,26487587,26573960,26606005,26640665,26674108,26726320,26832022,26880519,26936869,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respectively;
The positions of the SNP loci on chromosome 8 include: 186271,220987,240492,266757,294720,323671,350137,390206,423879,453857,486343,525112,558379,582945,613773,636539,660944,695943,734398,758565,831649,876613,915745,943496,971298,994759,1026619,1053621,1085374,1114974,1135242,1152074,1168708,1191510,1265149,1287645,1355919,1376122,1402566,1423482,1452615,1478325,1510233,1536758,1563428,1588509,1611169,1641167,1675219,1707272,1776376,1798179,1817799,1837443,1863383,1901110,1927246,1955393,1986262,2008847,2033642,2051979,2077072,2091879,2111830,2136501,2159512,2181472,2207709,2221208,2238977,2264525,2284777,2307223,2362100,2455325,2485492,2512560,2537271,2566825,2596341,2630935,2684495,2716359,2742089,2769298,2826822,2861030,2889651,2912529,2938619,2964503,2996150,3029672,3082618,3134712,3156668,3171662,3193785,3213092,3234119,3256288,3276650,3299369,3323760,3344541,3363441,3386424,3408229,3422471,3442377,3460557,3479964,3498904,3519063,3538528,3559268,3572647,3588760,3605823,3626217,3643120,3661040,3679619,3699344,3737310,3757018,3776571,3795261,3813492,3830442,3847994,3867910,3900551,3915562,3935720,3956297,3992617,4022412,4054448,4075464,4094658,4119457,4142987,4161050,4174631,4193502,4233767,4254058,4275087,4292832,4308183,4324194,4349565,4382286,4410318,4438436,4489464,4514626,4601254,4622263,4644553,4665649,4690488,4721066,4752088,4789067,4803200,4823714,4846986,4877391,4903970,4926972,4955782,4979961,5047528,5073843,5098285,5127400,5150901,5169199,5189283,5213378,5235928,5255235,5283533,5307217,5335495,5362900,5391562,5412893,5438215,5463043,5488335,5509574,5533627,5555962,5579775,5601342,5619062,5643720,5668625,5695063,5725285,5751753,5778414,5803576,5825826,5846504,5883949,5911954,5934489,5960848,5987937,6011141,6036358,6063568,6085381,6132391,6157388,6191167,6215788,6236602,6259136,6281138,6312346,6337080,6364575,6414013,6438204,6464103,6489190,6516722,6544798,6574104,6607821,6635600,6664058,6716282,6769704,6797103,6826140,6888488,6968854,7005008,7216021,7332979,7763738,8004693,8077066,8101188,8136280,8170081,8205287,8244991,8275605,8302079,8329260,8363740,8392274,8427415,8462948,8492809,8522632,8557526,8586386,8612786,8643992,8673320,8709716,8742067,8773510,8803696,8844117,8870543,8898016,8963610,9039838,9072121,9101373,9129826,9159630,9191554,9251693,9282466,9317106,9356802,9393831,9431033,9467624,9510067,9561945,9597824,9634944,9669885,9706115,9735594,9773359,9813236,9861916,9937455,9977476,10016471,10052546,10085359,10112595,10139470,10207418,10247816,10280039,10311704,10342122,10373694,10401785,10432909,10469030,10542007,10571465,10606954,10638401,10668637,10697649,10744284,10789345,10828598,10860846,10896425,10931497,10967122,11001951,11036975,11076418,11110753,11148157,11186674,11226071,11267737,11299256,11360494,11450783,11489579,11523106,11567992,11610567,11634650,11686487,11705779,11740508,11771619,11791320,11816929,11849745,11875316,11929422,12007364,12239662,12312540,12407103,12424140,12443223,12481030,12508172,12531178,12559874,12630974,12662403,12697757,12729545,12763577,12797831,12827931,12855570,12882634,12903974,12927207,12960335,12995420,13023950,13061579,13140305,13170576,13194053,13222549,13251422,13315983,13345414,13377700,13405541,13436422,13462198,13513544,13537834,13559526,13584946,13604103,13623608,13646455,13666813,13688497,13713791,13733644,13784153,13803680,13824535,13882528,13905752,13925152,13957144,13987423,14023484,14057645,14083622,14108630,14136161,14161272,14195730,14231670,14257880,14281719,14311502,14341787,14366045,14424429,14456327,14484778,14505171,14534352,14567061,14596584,14631530,14672930,14707570,14750415,14791669,14833412,14896349,14932322,14962249,14996765,15024895,15084051,15120258,15151088,15184032,15214803,15237968,15268341,15291893,15318517,15354418,15380848,15411783,15448124,15480206,15512783,15546627,15583206,15616572,15646305,15669365,15687517,15706522,15730153,15780390,15807268,15837443,15871892,15913605,15940614,16025885,16052589,16089634,16121873,16161121,16212273,16253333,16297220,16344655,16373068,16406598,16441593,16481944,16519891,16555109,16586902,16617343,16648148,16735406,16773420,16815577,16842829,16900593,16942849,16990621,17031164,17065569,17114512,17157044,17190038,17222967,17251155,17307015,17334539,17358496,17385836,17416251,17443470,17462624,17485789,17533418,17556506,17586307,17618569,17644219,17700055,17726054,17748582,17810390,17847984,17883147,17911937,17936982,17975547,18006140,18034779,18064807,18090403,18124916,18153569,18190845,18215623,18243113,18300954,18328552,18430602,18458721,18484830,18546582,18578496,18617010,18650909,18679225,18715533,18757176,18794531,18822548,18852397,18919720,18947351,18981713,19080556,19113646,19145226,19177567,19260240,19296468,19332546,19397288,19462667,19497883,19532298,19570709,19607661,19642088,19725412,19767298,19809427,19838578,19876797,19920578,19955920,19995559,20028210,20104470,20138261,20181698,20221679,20260760,20295746,20330469,20361185,20397418,20438736,20515550,20557049,20589564,20625285,20667432,20788373,20852077,20889926,20930056,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respectively;
The positions of the SNP loci on chromosome 9 include: 39360,105953,164831,205297,245032,271822,333416,361818,392670,423004,459345,494342,557844,591562,618813,647999,667391,691376,724217,751121,780835,803851,834655,857511,880438,906052,935503,978265,1015337,1046495,1078694,1113688,1169543,1205747,1243967,1278833,1307782,1338005,1372889,1413166,1451966,1479100,1506101,1560678,1617277,1649782,1685741,1715256,1744771,1774821,1821515,1853425,1889540,1922303,1965646,2011345,2055697,2095958,2135494,2169898,2201807,2265003,2299042,2342966,2377823,2414851,2486550,2522475,2553112,2593528,2632315,2665492,2697979,2734539,2777770,2819410,2864224,2901344,2936285,3022592,3059740,3096420,3134294,3166207,3205480,3250753,3299728,3452551,3521236,3584112,3627626,3688610,3729256,3766582,3812356,3854070,3928151,3966486,4008212,4111864,4151884,4184065,4255384,4285088,4316407,4373432,4401005,4434012,4470855,4507192,4549314,4593157,4631675,4658662,4696927,4727775,4755298,4825979,4855912,4902317,4945746,4999323,5052359,5100733,5193277,5233373,5269575,5318703,5360766,5397662,5433388,5464376,5506429,5553541,5606709,5653758,5700010,5746646,5889205,5945312,5995523,6051358,6148072,6201575,6254567,6299810,6413904,6462215,6515920,6600377,6629939,6658080,6685019,6716511,6747799,6788012,6828441,6864636,6942522,7006663,7041039,7082397,7120851,7154851,7187974,7224722,7261450,7294617,7325806,7361595,7456295,7497097,7529861,7560844,7595374,7640694,7677376,7713039,7747510,7788633,7878626,7916560,7959752,8002270,8045999,8094390,8132480,8208952,8244384,8309392,8334420,8367692,8397775,8430892,8470268,8508597,8556602,8636983,8675050,8710109,8743408,8769885,8834563,8866527,8904596,8933267,8955740,9000935,9068928,9110552,9149546,9189926,9235410,9274259,9318688,9357065,9396251,9464912,9498018,9540907,9580946,9619605,9661211,9709808,9747105,9780049,9812087,9845152,9879623,9908756,9942685,9975058,10011536,10048205,10116005,10147116,10190773,10230141,10263623,10290056,10336685,10380125,10420097,10455033,10487367,10561559,10671848,10708866,10752338,10836932,10884513,10931834,10974159,11007684,11033665,11071160,11098475,11125902,11162510,11199226,11239025,11269531,11311022,11438424,11476113,11515414,11557876,11594486,11623933,11660080,11698942,11734433,11767921,11800746,11835319,11868796,11908303,11952128,11998261,12032864,12078769,12117309,12166969,12203061,12275962,12313945,12347724,12370472,12399142,12452348,12495286,12586806,12632288,12673731,12709441,12748587,12785073,12830941,12866358,12892306,12927866,12961551,13011791,13058128,13102063,13161000,13224887,13277534,13332878,13386175,13445508,13493036,13532112,13562874,13599352,13675371,13716005,13751764,13781570,13812637,13851213,13879957,13919583,14010312,14045800,14088346,14141703,14224301,14266746,14312400,14402079,14442529,14487611,14532789,14567207,14608670,14649882,14694816,14733642,14811009,14847780,14887606,14934720,14979843,15063368,15098525,15133328,15171759,15216293,15258922,15292455,15332701,15401044,15442541,15477436,15520755,15615321,15678259,15726267,15824541,15952258,16037030,16081813,16122631,16162525,16202674,16226780,16262884,16301484,16334986,16408826,16454714,16493143,16528611,16573486,16618001,16667341,16710899,16749782,16815861,16886487,16910898,16935343,16961173,16992122,17030305,17064226,17112944,17151510,17195804,17238393,17274815,17344907,17468106,17506823,17547664,17580292,17652883,17690174,17721401,17746569,17778061,17818007,17858434,17898857,17937633,17972120,18016573,18063949,18104533,18143954,18187511,18237789,18275275,18305489,18348274,18395119,18432139,18478894,18522832,18565216,18601951,18634268,18670579,18719142,18761687,18837987,18882257,18911778,18943380,18971932,19005829,19035850,19076313,19117038,19154738,19190629,19233679,19266141,19306663,19347663,19390407,19430459,19472080,19513554,19593235,19642524,19683409,19723243,19762691,19812437,19861933,19900013,19944652,19990073,20031656,20070944,20115057,20162853,20204823,20242344,20280828,20323424,20376023,20443334,20502104,20589530,20630614,20735804,20785784,20840240,20897424,20989643,21034163,21081822,21129739,21171823,21202867,21236589,21282578,21328806,21368666,21417570,21460710,21507183,21553178,21601812,21675670,21711815,21743288,21781867,21826463,21864552,21918203,21967676,22010412,22063019,22133984,22160768,22196508,22244294,22288403,22329580,22379411,22420204,22465207,22509658,22549535,22591196,22637057,22732903,22780966,22872321,22914592,22950406,22988063,23026272,23065716,23099607,23136745,23173989,23264340,23302726,23347980,23385738,23424567,23516909,23561054,23607571,23679709,23721349,23767047,23815595,23924422,23973389,24061320,24105279,24148652,24185915,24243377,24291960,24389265,24446133,24551983,24607643,24649916,24725322,24773842,24818504,24852695,24895277,24930442,24970615,25012405,25059297,25124412,25161718,25239583,25285076,25385116,25415713,25451237,25496001,25538406,25612202,25722614,25765616,25782400,25825227,25870079,25924324,25968015,25995534,26033758,26087831,26141431,26190855,26242441,26300424,26349577,26394764,26451025,26498623,26532846,26571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633,141063232,141084494, respectively;
The positions of the SNP loci on chromosome 10 include: 106126,137212,202527,261650,315732,390358,419916,444555,471339,501504,538317,574326,607922,678000,723150,761649,777642,807330,837450,881998,936873,991644,1061665,1132980,1170496,1205850,1234510,1270534,1307655,1343759,1376968,1407539,1434704,1494010,1515644,1551548,1583406,1605704,1626935,1651002,1675929,1705879,1738482,1765005,1851858,1917708,1977423,2046453,2101136,2172065,2207785,2278085,2310137,2344595,2371598,2399399,2433400,2466878,2504343,2535669,2562642,2625209,2656120,2694562,2730860,2766759,2794937,2829929,2874739,2914753,2954160,3039787,3071854,3096617,3121077,3146155,3163175,3180298,3212358,3246569,3276965,3409675,3453522,3487380,3521369,3605732,3658059,3735925,3770581,3803035,3837555,3869607,3906885,3940706,3965873,3988667,4021907,4062327,4103901,4140580,4168171,4218425,4251861,4364598,4404105,4525591,4555699,4597847,4630288,4657550,4696289,4740045,4784070,4824926,4886868,4915912,4961369,4995058,5027931,5056002,5090805,5129139,5151354,5179882,5214831,5252902,5325918,5363083,5397491,5471470,5510802,5546087,5619116,5647078,5681032,5712693,5802956,5842240,5886570,5958072,5991569,6021885,6052068,6079483,6112291,6150311,6182749,6211592,6238963,6265329,6301078,6341206,6373848,6454924,6488017,6527270,6564883,6611621,6687618,6726766,6764797,6807730,6846265,6913849,6973882,7009557,7038968,7081699,7117594,7149998,7194265,7239793,7274741,7312200,7361749,7404505,7445901,7490206,7523475,7555492,7588290,7622217,7686343,7721859,7756155,7795548,7877290,7917798,7969567,8065087,8099629,8123191,8150102,8183039,8217921,8249865,8283928,8321660,8362245,8397816,8464581,8550507,8582358,8658846,8702460,8740732,8781277,8897261,8945648,8983047,9023719,9058671,9094424,9132408,9171654,9213854,9259428,9306064,9349500,9452439,9512428,9553961,9612515,9671078,9796000,9857091,9910828,9955333,9991667,10029896,10065438,10104399,10140203,10220981,10262842,10300168,10326331,10370918,10422594,10510959,10556072,10592979,10629297,10668715,10718024,10758526,10800504,10844526,10892091,10979955,11033600,11084164,11158063,11197845,11239010,11275566,11308616,11346374,11388639,11418955,11456364,11492868,11543086,11656848,11699856,11730196,11759046,11821473,11858114,11896420,11928072,11957748,11999791,12047767,12087005,12161411,12206169,12253183,12294890,12324964,12426386,12499594,12533173,12566199,12598121,12663986,12743559,12778206,12807287,12836751,12869284,12893229,12941153,13001186,13032586,13069718,13103657,13134648,13169264,13211533,13250133,13281667,13313259,13348512,13433417,13473087,13511986,13554112,13599687,13642872,13683519,13714057,13741505,13772503,13808113,13832761,13859564,13896605,13926123,13959305,13989216,14028674,14093716,14131835,14166745,14235685,14273535,14306643,14344556,14378449,14415867,14440662,14476854,14512559,14552207,14592997,14623195,14661117,14757013,14800569,14829883,14863375,14918316,14965511,14995464,15027645,15098311,15134623,15170431,15214537,15257383,15298555,15342661,15450994,15522841,15548747,15583365,15616714,15656020,15698576,15745059,15785720,15829458,15887674,15943681,15988352,16025697,16113376,16150889,16187157,16232149,16271816,16313333,16348783,16383058,16419974,16444680,16477500,16515573,16553349,16591841,16626515,16674290,16710032,16742510,16779757,16818105,16849659,16877859,16921214,16965178,17063577,17144768,17181979,17222557,17259863,17298472,17331544,17397448,17424271,17466752,17507512,17542447,17587121,17702921,17740411,17793756,18358517,18397597,18436647,18470174,18663585,18702356,18770298,18808692,18847041,18889907,18975185,19004994,19045354,19088771,19127973,19173550,19246810,19387126,19426549,19459979,19490933,19519981,19551922,19627998,19662132,19762077,19793829,19828832,19875303,19912246,19943290,19988543,20080740,20120750,20155618,20199105,20239338,20282191,20318588,20352631,20429371,20471205,20509788,20547231,20624933,20661179,20740616,20780095,20819892,20892992,20934100,20975654,21012039,21058596,21143722,21187945,21236507,21277980,21356409,21394129,21445236,21528348,21615569,21647453,21697652,21749246,21809706,21873712,21996118,22061494,22277065,22339708,22463594,22564924,22629414,22689404,22738919,22791353,22833928,22872674,22910489,22950152,22995580,23044757,23137721,23185723,23237568,23328733,23469422,23528023,23580946,23631278,23677090,23717462,23755039,23795334,23883517,23922510,23976996,24018500,24101521,24135231,24187192,24226419,24268482,24312048,24415337,24467351,24502629,24547110,24593546,24637755,24675218,24764631,24807097,24850658,24904115,24967176,25028479,25078088,25124826,25166578,25197663,25240084,25285385,25367066,25417504,25460936,25523699,25577521,25641379,25668917,25709364,25739714,25784245,25829906,25917909,25956113,25994034,26024322,26063061,26110653,26154038,26182569,26221380,26273616,26315345,26346047,26366576,26421847,26471289,26516639,26549427,26589814,26617542,26657758,26696509,26733753,26768622,26814137,26857582,26874089,26924489,26938434,26961039,26984146,27016642,27063077,27112414,27144553,27179667,27215087,27233815,27265194,27314400,27360773,2739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respectively;
The position of the SNP locus on chromosome 11 comprises: 186225,205758,301299,332857,362061,394665,428894,470150,495892,531062,599155,636461,662811,701511,736460,780319,824293,887015,931799,971688,1016609,1048374,1079027,1093452,1119614,1154827,1224269,1258588,1290894,1330152,1377056,1413639,1449565,1532338,1575670,1626037,1651652,1677653,1706937,1742965,1790150,1880476,1920285,1960891,2002472,2038229,2085021,2132045,2170469,2201704,2231349,2269704,2306634,2337272,2373180,2406978,2478026,2524548,2559352,2596711,2752609,2790163,2828338,2896265,2932944,2963620,3001707,3046342,3091216,3125123,3159032,3200384,3236659,3265321,3393111,3431570,3460965,3481958,3509344,3552004,3588970,3609056,3641598,3674741,3712835,3757641,3843530,3890633,3939122,3989890,4047427,4111535,4151228,4180989,4218375,4253684,4270500,4324189,4366064,4409386,4438810,4474554,4515197,4541983,4563242,4586317,4603546,4641442,4678242,4714611,4755505,4789887,4895735,4968738,5004564,5042908,5072638,5103959,5143153,5212996,5237393,5259534,5305617,5339206,5371325,5389950,5416842,5443190,5541143,5570035,5626855,5665489,5696254,5721770,5759613,5795254,5828299,5859536,5887322,5956729,6006661,6049351,6099795,6132203,6176913,6228520,6280480,6312846,6350437,6396587,6440813,6483202,6575339,6677327,6796872,6830891,6862782,6923211,6961131,7009080,7055286,7098907,7192075,7242044,7284167,7373772,7414065,7450649,7482895,7521640,7566736,7599301,7639428,7676015,7709267,7752848,7784484,7810214,7839051,7869683,7902372,7935873,7973731,8062377,8104427,8143837,8186355,8212769,8251803,8286932,8326457,8353044,8392316,8499504,8558498,8709867,8761759,8816495,8858119,8903822,8995949,9093422,9134643,9185605,9236628,9283013,9364326,9401736,9506177,9554191,9670655,9748215,9792362,9836501,9961331,10003145,10116049,10175364,10227680,10274933,10370420,10404791,10528464,10566590,10611588,10657446,10700729,10778510,10823815,10904758,10945233,10998548,11032143,11068048,11138806,11176356,11210169,11246948,11309993,11336349,11369637,11404718,11447955,11490518,11530545,11566037,11601816,11641054,11688517,11744879,11826643,11862764,11915319,11976272,12018220,12059701,12095982,12126320,12159411,12193229,12225196,12379245,12419183,12459482,12504234,12543675,12582905,12623377,12661846,12719114,12766669,12811468,12857056,12902806,12985347,13026026,13072198,13111716,13135183,13167357,13206664,13241079,13282833,13322880,13375473,13437904,13495469,13547311,13594557,13696617,13754422,13796776,13835142,13927332,13972159,14119736,14165239,14207955,14312165,14388096,14457043,14522336,14593295,14675144,14765551,14859567,14990358,15036053,15096436,15142726,15274895,15319496,15365043,15413057,15468407,15518646,15571622,15615558,15662123,15722346,15767265,15816748,15865940,15908016,15953077,16002506,16067724,16134476,16203475,16255448,16311602,16381377,16441622,16499169,16559229,16692883,16762077,16817208,16862621,16941060,17028918,17076769,17127874,17185340,17229613,17331808,17393494,17430963,17467208,17499915,17577424,17620442,17668718,17720159,17768321,17823578,17890017,17940233,18013306,18065663,18118813,18165606,18201216,18237905,18272796,18309700,18353893,18396256,18432941,18469934,18508182,18559844,18658277,18707047,18799075,18915162,18960024,18998233,19045102,19091089,19132288,19177378,19266703,19351584,19399410,19436436,19477994,19518957,19556008,19594730,19641132,19689986,19729009,19776931,19823622,19868759,19988585,20021067,20058714,20103543,20308258,20429807,20472242,20519747,20560067,20604880,20638193,20673648,20710292,20748931,20778475,20817314,20937083,20982573,21013561,21051852,21091312,21134227,21177875,21217137,21350085,21391665,21427726,21471038,21510922,21586422,21618445,21652001,21727365,21759573,21792928,21821386,21892932,21938781,21997909,22051095,22089972,22130036,22217716,22262561,22304792,22347398,22388389,22430075,22468755,22508748,22543999,22586703,22625975,22672879,22705197,22794722,22838241,22886524,22925948,23014757,23050978,23081570,23112442,23144273,23180412,23246914,23279497,23315221,23362565,23405973,23480422,23511166,23534915,23571435,23599147,23641822,23695276,23779188,23818156,23861993,23904035,23983637,24025144,24069488,24100886,24238996,24315454,24361623,24436369,24479651,24512796,24579960,24610658,24641758,24686842,24763954,24796544,24835048,24859404,24889776,24918992,24967933,25010942,25042995,25074235,25107386,25142907,25178022,25207556,25246318,25291724,25332574,25370777,25411788,25442838,25527596,25562027,25602435,25637425,25697295,25739334,25771901,25869524,25909191,25939971,26008162,26070041,26147244,26232078,26267820,26305547,26349901,26399966,26434865,26479615,26522262,26557279,26588804,26629408,26661700,26692638,26777535,26942119,27000512,27051464,27092430,27190529,27235977,27335858,27384469,27439620,27494569,27551742,27617566,27671986,27738382,27850631,27917542,27990046,28060285,28133132,28197561,28275212,28357686,28427542,28490811,28553814,28617815,28678477,28733552,28789848,28837633,28874514,28966148,29016843,29066513,29181399,29237351,29286442,29343831,29397132,29495831,29540884,29625242,29669503,297177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The position of the SNP locus on chromosome 12 comprises: 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The positions of the SNP loci on chromosome 13 include: 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29053,111150024,111177434,111202064,111236766,111269277,111302424,111330368,111370615,111420998,111459104,111495176,111533874,111575914,111620931,111661710,111695934,111728767,111761068,111807859,111858911,111905979,111950692,111978995,112009831,112038273,112066812,112095246,112128232,112160860,112193040,112220547,112248013,112283058,112313712,112526399,112558019,112592004,112617208,112662652,112691474,112806296,112839317,112907759,113008064,113044780,113082171,113108685,113151299,113198563,113244418,113285909,113318840,113354375,113388046,113418574,113441991,113471811,113500484,113527319,113561806,113630385,113664067,113686197,113716509,113746250,113774092,113812897,113847762,113889228,113933651,113973270,114000425,114022946,114051002,114079018,114101311,114136405,114166154,114195692,114221765,114262351,114294059,114457899,114497396,114523062,114544536,114579004,114616923,114752791,114774439,114823936,114848968,114942160,114979319,115011854,115048168,115087313, respectively;
The positions of the SNP loci on chromosome 14 include: 19004241,19014220,19026535,19040054,19048893,19080173,19109812,19265588,19435427,19484909,19744897,19820800,20113335,20207317,20245067,20280927,20318112,20378549,20411078,20486786,20520675,20590513,20638141,20672763,20711469,20758366,20805662,20839307,20881138,20919319,20957923,20993439,21032595,21074683,21107126,21181461,21212108,21241596,21311645,21349932,21401495,21477616,21515528,21552835,21597014,21631457,21680716,21727988,21773480,21813156,21860866,21968504,22012216,22077177,22108653,22144071,22188829,22233399,22310189,22411486,22440258,22476144,22516578,22545241,22586343,22616049,22652274,22718330,22751334,22786996,22835396,22880443,22926919,22970035,22995074,23074899,23113817,23210109,23242980,23305751,23345287,23391086,23436369,23493504,23543881,23660058,23735900,23791520,23845461,23882350,23905751,23948928,23999814,24109696,24154702,24184084,24220391,24252018,24291771,24338431,24382212,24421676,24461507,24513520,24714264,24754046,24800577,24839897,24888697,24954202,24995331,25052827,25149580,25243751,25285846,25345898,25390661,25431699,25482474,25537228,25577942,25620327,25659076,25736541,25769922,25803217,25849033,25887349,25923648,25973239,26016909,26066679,26107494,26147126,26188556,26237458,26294886,26356384,26476094,26520201,26558679,26599561,26703176,26752004,26793599,26829859,26873787,26927111,26992064,27051340,27163828,27205328,27315523,27376505,27440457,27541667,27624981,27731432,27822638,27867818,27915411,27973832,28066265,28118949,28167755,28259669,28297700,28320904,28366190,28416025,28459002,28504321,28547260,28593927,28636781,28689161,28739646,28840617,28880796,28930035,28983650,29022242,29061653,29098755,29147346,29192618,29303677,29430305,29541494,29655520,29719646,29772059,29836773,29900195,29956060,30003024,30085236,30118463,30162013,30215086,30326858,30375428,30425562,30534152,30583474,30633717,30683130,30741045,30803862,30854448,30911690,30972850,31023554,31073297,31120787,31179594,31268748,31309814,31353247,31397476,31486706,31528062,31585174,31631771,31685061,31729807,31773068,31822149,31872749,31914971,31959641,32004528,32052978,32104842,32193674,32232732,32276011,32310250,32352633,32396952,32426604,32520038,32590304,32651796,32765622,32812511,32848218,32893342,32967586,33013596,33063524,33111792,33162621,33207400,33248858,33289463,33325196,33412626,33453647,33496978,33548252,33590891,33633155,33679447,33729340,33777735,33814021,33850155,33898971,33942623,33990830,34075510,34125226,34165057,34210238,34257510,34306451,34347610,34393602,34433221,34468721,34506408,34548054,34592274,34642612,34718605,34802241,34876199,34917022,34952887,34989817,35044556,35092927,35135607,35176730,35210156,35256361,35302350,35342838,35385655,35424436,35570816,35618360,35658638,35709009,35760054,35801346,35871444,36045942,36117545,36186182,36247283,36306407,36367009,36417777,36454580,36500842,36545461,36584219,36680746,36727174,36783877,36841159,36891135,36945392,37001352,37045498,37091499,37132248,37223166,37263178,37307414,37394567,37441176,37487132,37575793,37617232,37665045,37779265,37829448,37885731,37948621,38006519,38061336,38121370,38174634,38212551,38269967,38318172,38376573,38488659,38544470,38591024,38678056,38736784,38782096,38863987,38947357,38994672,39043263,39087408,39136292,39187312,39242720,39300780,39351589,39405310,39452687,39554078,39635469,39667661,39758196,39792555,39886855,39991127,40046317,40155469,40196876,40252768,40306839,40350587,40402365,40447058,40503709,40550580,40587407,40677483,40788882,40843130,40884074,40919556,40954725,40989521,41019126,41049211,41076770,41112714,41157196,41205566,41255667,41303944,41338165,41430022,41474756,41506225,41527131,41568836,41602337,41678659,41727607,41771455,41819091,41873129,41917702,42029085,42092402,42153162,42198410,42320790,42422532,42472305,42509986,42547285,42589387,42631920,42679654,42719876,42758259,42800019,42872292,42914536,42957137,43048131,43093153,43135501,43188383,43233288,43279961,43330160,43379414,43422101,43464405,43501589,43540246,43574709,43615856,43664043,43723085,43776163,43823570,43868549,43912336,43957047,44003136,44053466,44096772,44140830,44192700,44242704,44339448,44402502,44444697,44491754,44536876,44581257,44629572,44669124,44725022,44770916,44821980,44879327,44961819,45001676,45042709,45051733,45094980,45145699,45191205,45245255,45307793,45364920,45416026,45480376,45540960,45612664,45675772,45741270,45816340,45889010,45961699,46065940,46125095,46178308,46230859,46275487,46322950,46352072,46389898,46432793,46475174,46516539,46606306,46653857,46697082,46742642,46791230,46837024,46888821,46934687,46975411,47022731,47080771,47128019,47218924,47266095,47323422,47388474,47431531,47478505,47567007,47612161,47725989,47768412,47808059,47854101,47898038,47945667,48006771,48064755,48117246,48242149,48284452,48355496,48398664,48439631,48489272,48568453,48642419,48701173,48750194,48843135,48900342,49021398,49075229,49169314,49228155,49281568,49370571,49464841,49513651,49562370,49648421,49699543,49748071,49789020,49925776,49973195,50022044,50105684,50151115,50212718,50262257,50310018,50357061,50438798,50478492,50560177,50640128,50765502,50800588,50846269,50895137,50997546,51058234,51107737,51185923,51228655,51278057,51318288,51354682,51391006,51431223,51509390,51549634,51595335,51638966,51689905,51739293,51784942,51910661,51956718,51997580,52044247,52082661,52129311,52180569,52222161,52270982,52350131,52395480,52428759,52472795,52501902,52529083,52570890,52614501,52645705,52675539,52756594,52798092,52838084,52883981,52938919,52992462,53037128,53151341,53209963,53413208,53551106,53613974,53663595,53704749,53754559,53797644,53827368,53881839,53933920,53984191,54043150,54102009,54153107,54194185,54240454,54299289,54392613,54441614,54491149,54547435,54592962,54646469,54689343,54754604,54804507,54843017,54884511,54936346,54994826,55053210,55094425,55143117,55185030,55268294,55316232,55367416,55405427,55454956,55507628,55561232,55726425,55769883,55810831,55849213,55895104,55923210,55956526,56038180,56088860,56136040,56181300,56221819,56307085,56348839,56387545,56426945,56474458,56518856,56557345,56603088,56660107,56696472,56743073,56871878,56927344,56963182,56997940,57073932,57119945,57162880,57207836,57342832,57381105,57427625,57473275,57555827,57708608,57771773,57829026,57886005,57938118,57980417,58022794,58107933,58144371,58226607,58275992,58323765,58363425,58433026,58517384,58566228,58685833,58741618,58795687,58931528,59060102,59112475,59157919,59241220,59282645,59325631,59366252,59422619,59460548,59501704,59543107,59582631,59624317,59678626,59777688,59827386,59863176,59907789,59956113,59995842,60045199,60093819,60165473,60269379,60328427,60402519,60464145,60520579,60675060,60779031,60842391,60917496,61031284,61085141,61138847,61182085,61254110,61321331,61384863,61450658,61575640,61616263,61654643,61693613,61731920,61835400,61879332,61919216,62064257,62112982,62299007,62350814,62397867,62459095,62502340,62539699,62677341,62758340,62803697,62888268,62919811,62989803,63034299,63079703,63105687,63147993,63199660,63248290,63343862,63493537,63542044,63598207,63642791,63743564,63783052,63825672,63863816,63909290,63945101,63982105,64067436,64109428,64164425,64214837,64266131,64312318,64355806,64403654,64497929,64541600,64587401,64687710,64724993,64780116,64832600,65030190,65089468,65135586,65182316,65232095,65268451,65307246,65352423,65437562,65491804,65549089,65599443,65635440,65720143,65762051,65847351,65896041,65991737,66049184,66100768,66152004,66205649,66253437,66296087,66339725,66388000,66431896,66475442,66517776,66563491,66675364,66729277,66788116,66846217,66909881,66957196,67013165,67058902,67059238,67106634,67150673,67206082,67257994,67311322,67373863,67431696,67495340,67541422,67601861,67656917,67708717,67758504,67805014,67855598,67905423,67987253,68035175,68073358,68115459,68161356,68206891,68248774,68298812,68353879,68407385,68464273,68592542,68641096,68705020,68754824,68799303,68895693,68941989,69039588,69074606,69118241,69158040,69198917,69232191,69275310,69390185,69432044,69476895,69521338,69575941,69635175,69687045,69778816,69822927,69866847,69924302,69971627,70026853,70084011,70136653,70188636,70233186,70276933,70319261,70362890,70401755,70442987,70488431,70579715,70615594,70650834,70693175,70732443,70813520,70857022,70897737,70940591,70990385,71043556,71085059,71169310,71212158,71253992,71330918,71373580,71422789,71469015,71525765,71586319,71628063,71663816,71707781,71829782,71892566,71963428,72032351,72109945,72185653,72245203,72293012,72334597,72376451,72421334,72465383,72496823,72582474,72630071,72705363,72738833,72778834,72816180,72906389,72950438,73027000,73064446,73109766,73158413,73205950,73282419,73318473,73356299,73392938,73429916,73466280,73556416,73602899,73649732,73728386,73770312,73824215,73867487,73908201,74005488,74050321,74087595,74131122,74168431,74216606,74299507,74373609,74416646,74533691,74574163,74615378,74651913,74691932,74726009,74756776,74793881,74841467,74886168,74931153,74982212,75075785,75182315,75241606,75307588,75356799,75450199,75546250,75603239,75654933,75750466,75871657,75917207,75957952,76038388,76087014,76139134,76258581,76321510,76372254,76429157,76475949,76523191,76570684,76613678,76656460,76741336,76815889,76858983,76899467,76932061,76973328,77006765,77083749,77126240,77151803,77186640,77229532,77281882,77354554,77397668,77440625,77480599,77553906,77597268,77637976,77697637,77738918,77788749,77833808,77880104,77925154,77958858,78055036,78089870,78162617,78203650,78244635,78282771,78356245,78401921,78534475,78571385,78612850,78698154,78739383,78825609,78874209,78919999,78962030,79004001,79059667,79105473,79252797,79296488,79356051,79449663,79490575,79570322,79621431,79660882,79711725,79761736,79827037,79877592,79935212,79980316,80024861,80068984,80108238,80157170,80203080,80301514,80390370,80474190,80533865,80584555,80639349,80694103,80770565,80837785,80884583,80936298,81039132,81092103,81127849,81174506,81226088,81280664,81330921,81373372,81416915,81546732,81586470,81696252,81754764,81846334,81890783,81930632,81984211,82037158,82070720,82115590,82154566,82241899,82280449,82332888,82386690,82432678,82477473,82520202,82620849,82708203,82824035,82931168,82980080,83024189,83069532,83115807,83207636,83255356,83286588,83320597,83361570,83402539,83425981,83472053,83515665,83587036,83636576,83692040,83738652,83786594,83890773,83934765,83971295,84013541,84070701,84180897,84226499,84272291,84323330,84370060,84507306,84562548,84603270,84688008,84730189,84775080,84826658,84922787,84975733,85019563,85057698,85152219,85198677,85247702,85302778,85357812,85448144,85590078,85632914,85716135,85757494,85805180,85835554,85850495,85891138,85930269,85978782,86020497,86100578,86135234,86168332,86207286,86242052,86285115,86430609,86458994,86518217,86577671,86623834,86672760,86750434,86827806,86905543,86934182,86975245,87017901,87074975,87135417,87182870,87242598,87294758,87340547,87393296,87450938,87506248,87553025,87645184,87705438,87743893,87784378,87828466,87873861,87916052,87965993,88014118,88062686,88109684,88151708,88193968,88233941,88285116,88330540,88368443,88394809,88423820,88461498,88510109,88544791,88589635,88639955,88718699,88759715,88802133,88849897,88892375,88944331,88984048,89039729,89089485,89151052,89206243,89269127,89423154,89457054,89498009,89531426,89571030,89609980,89655336,89695798,89739386,89779833,89818623,89855072,89929230,89970343,90049492,90138781,90188194,90230779,90315184,90373881,90450846,90488460,90534501,90580303,90610293,90648307,90699901,90738171,90785895,90825718,90913293,90957628,90992743,91039140,91095838,91136964,91181269,91226569,91265601,91304045,91345960,91399611,91450940,91543797,91592036,91680540,91772285,91816479,91857602,91904947,91951338,91993143,92035928,92077878,92119574,92162277,92203773,92297421,92380018,92423766,92508917,92547425,92620047,92658802,92692026,92755472,92797887,92837511,92873893,92910740,93014385,93056912,93099890,93130713,93167758,93209006,93250704,93289821,93333680,93373707,93410415,93456731,93505244,93559288,93600914,93673934,93768589,93806831,93859578,93920767,93972848,94026035,94081739,94139021,94199372,94240749,94287160,94357905,94391699,94432478,94470185,94506299,94547064,94626667,94678228,94735739,94776153,94814039,94843499,94870171,94909051,94939787,94978311,95018592,95054272,95083926,95121464,95143114,95174621,95259000,95288761,95325563,95353389,95383411,95419570,95461154,95502751,95600426,95660684,95708491,95749011,95795387,95833706,95870214,95899197,95930986,95964196,95996319,96030981,96060549,96084904,96116687,96148850,96184969,96223418,96268607,96304178,96395892,96434973,96474605,96562047,96597658,96630854,96667677,96707598,96747391,96794874,96853872,96903854,97062957,97144256,97180875,97254594,97350977,97397509,97446450,97490979,97571437,97608212,97644266,97694239,97747012,97803040,97892795,97933671,97977153,98020723,98126090,98170611,98207691,98240735,98273322,98345806,98411556,98447779,98484983,98557257,98589272,98635154,98670418,98708339,98741998,98775077,98804790,98831026,98867516,98899211,98934144,98971909,99016587,99087085,99165309,99244885,99278602,99318919,99363448,99433568,99471244,99506719,99545932,99658045,99746348,99791631,99866722,99977411,100018442,100046229,100088334,100168462,100210370,100295252,100389164,100472357,100559832,100607779,100655022,100708066,100750084,100796490,100835820,100882998,100980040,101022672,101068210,101106995,101149511,101183950,101231438,101274804,101319020,101364609,101413202,101464984,101509044,101544539,101581293,101650894,101676148,101706307,101752324,101795599,101891883,101934952,101971689,102080283,102129590,102240913,102301836,102346833,102389881,102425872,102516770,102552369,102604715,102653746,102699636,102754257,102803765,102861331,102911988,103001411,103048904,103099176,103144583,103249935,103302070,103362017,103407730,103481561,103526168,103568047,103607031,103636813,103677821,103709151,103866269,103908433,103986086,104035519,104085832,104133392,104172704,104218890,104266997,104315440,104358076,104389231,104424583,104516391,104563758,104611350,104681383,104740379,104767818,104836132,104881564,104919105,104962606,105024514,105063116,105104208,105147219,105231196,105266062,105309599,105346869,105386557,105424199,105468992,105593686,105636112,105776114,105828530,105884961,105929505,105975810,106022680,106051834,106089676,106114658,106148130,106186614,106208431,106234422,106273250,106320953,106334873,106466727,106484048,106517972,106542044,106576854,106604176,106638090,106677042,106710300,106733078,106757831,106773780,106785946,106806761,106822237,106855111,106870367,106879407,106901990,106924739,106941875,106975947,106994922,107018715,107031449,107045343,107070795,107094572,107108755,107150281,107161917,107170018,107179243,107195328,107235114,107256858,107286255, respectively;
The positions of the SNP loci on chromosome 15 include: 20009785,20017858,20033729,20045291,20066842,20084355,20109261,20120757,20137849,20166367,20262236,20412850,20439889,20455929,20471978,20493792,20513591,20540441,20557173,20584498,20605746,20740367,20864117,20886919,21122899,21160981,21922309,21940821,22011563,22299450,22351505,22378655,22402353,22427629,22461786,22491346,22516147,22540799,22569637,22742752,22803850,22829776,22863553,22903717,22941425,22979867,23091321,23190414,23608622,23718659,23752260,23796444,23843033,23921881,23972360,24056556,24091600,24133122,24172569,24226382,24256344,24331296,24357725,24390787,24418868,24444265,24495576,24521262,24561516,24585853,24610877,24635315,24663979,24694918,24740532,24778603,24800794,24825142,24857494,24899949,24983390,25120270,25182585,25231046,25283881,25321029,25366726,25415222,25443773,25478225,25521716,25580637,25640964,25694320,25741011,25779886,25890580,26070216,26110473,26136374,26201756,26260992,26305413,26347929,26390185,26426824,26472365,26523035,26570398,26608213,26695034,26743246,26792934,26835167,26878772,26924444,26962228,27002886,27034320,27063163,27102991,27209075,27264253,27305701,27412400,27461603,27501315,27602224,27644946,27695885,27745346,27778589,27820352,27856075,27891937,27970378,28010462,28052654,28094153,28134674,28173598,28269487,28369328,28430939,28484131,28705226,28962131,29075647,29224454,29263425,29309862,29351982,29391798,29425002,29460356,29511631,29550943,29595240,29721356,29763544,29799511,29846417,29931280,29973725,30072614,30129196,30193097,30282139,30331658,30938533,30998495,31036898,31116585,31315570,31364474,31405422,31440597,31487807,31563438,31607115,31658025,31706416,31747312,31781988,31823590,31872185,31966607,32018274,32069223,32113955,32162787,32211144,32307908,32355086,32400547,32444185,32823831,32990026,33027179,33062903,33092196,33130073,33168360,33203874,33241706,33306996,33333116,33367649,33403988,33465227,33577798,33616345,33663077,33699848,33743396,33779446,33824335,33862539,33941144,34015960,34048707,34080892,34114212,34149427,34180957,34208859,34242369,34277300,34357259,34435998,34603212,34639049,34671726,34725342,34780907,34862151,34876077,34928299,34975679,35010136,35044302,35084122,35126486,35182441,35237294,35287884,35332631,35459109,35503175,35556177,35684068,35734680,35990383,36132971,36227467,36268701,36314715,36357252,36453533,36518642,36567143,36612233,36664355,36707838,36871609,36967086,37017096,37105935,37165621,37267426,37312922,37523136,37563352,37619728,37674816,37728886,37785689,37877853,37933226,38035198,38086227,38136326,38170700,38269523,38318525,38362765,38475391,38618155,38662192,38702126,38741616,38788948,38840251,38904747,38994348,39029230,39063533,39110442,39158933,39196185,39236104,39271677,39305160,39382946,39426330,39465776,39509073,39588417,39621773,39704875,39746294,39790698,39833895,39874092,39920918,40001306,40081691,40139851,40181575,40228178,40270655,40359569,40400135,40446293,40550842,40593776,40643717,40691554,40784859,40835667,40871119,40912913,40965452,41012180,41060774,41157497,41257227,41351332,41407912,41458024,41497746,41542681,41601148,41663900,41789091,41833029,41880619,41936997,41994315,42059002,42122842,42168373,42212184,42262847,42336450,42377654,42416720,42469260,42571166,42614339,42652961,42734482,42797305,42849431,42903816,42969116,43021628,43150834,43303380,43379773,43452179,43579740,43694826,43749151,43912372,44020649,44076044,44137510,44199681,44265203,44329256,44396035,44445608,44504115,44566788,44660646,44738326,44813274,44878370,44950097,45018637,45106447,45156734,45209094,45255937,45308473,45391499,45437272,45484557,45524936,45565159,45609865,45655354,45719359,45762756,45834294,45903472,45948384,45986665,46019231,46073591,46161483,46250715,46289278,46380008,46437802,46484904,46525152,46574136,46626779,46678078,46773567,46822494,46869577,46899542,47052778,47108711,47164930,47217699,47327657,47367066,47390356,47428854,47492259,47539068,47591464,47640608,47678132,47717864,47765152,47814878,47868142,48023870,48075941,48114589,48156544,48262588,48314553,48379368,48445505,48523822,48567525,48615918,48662483,48704790,48745479,48784981,48835420,48893649,48945759,48992954,49052785,49163102,49264185,49326412,49381897,49436289,49615783,49677023,49734968,49786481,49843340,49895046,49947688,50053150,50106638,50153674,50209467,50258166,50309413,50365389,50488859,50531372,50581882,50629314,50670121,50716635,50811906,50848271,50889693,50928155,50964964,51049989,51139135,51232051,51347471,51403444,51456110,51502082,51547931,51589285,51629104,51709365,51773357,51838794,51895072,51944563,51993004,52040379,52139416,52185734,52233754,52384454,52461760,52507009,52598500,52648468,52876523,52929465,52982876,53028304,53071207,53124885,53172666,53206030,53242242,53333746,53375933,53410566,53456044,53500433,53536741,53579889,53622101,53709656,53762511,53803160,53847083,53925277,53964193,53998829,54031981,54068345,54146936,54183560,54219071,54251812,54287662,54333143,54372638,54479054,54518159,54550097,54631840,54672830,54762105,54800092,54846070,54895577,54934393,54965345,54998764,55035232,55071943,55111984,55165718,55205011,55281093,55325407,55367434,55408162,55454917,55496111,55534998,55578596,55630984,55715606,55763693,55812332,55849196,55893245,55937709,55985033,56028539,56063330,56185654,56232745,56270335,56314041,56350171,56445142,56502899,56551416,56603043,56650179,56746241,56786498,56831184,56878521,56931536,56994682,57052565,57162093,57225443,57268242,57313706,57359225,57401025,57448869,57530889,57574426,57612424,57651069,57678577,57746787,57814888,57851611,57884119,57923325,58009061,58047036,58082071,58121759,58159378,58196396,58240333,58275662,58313104,58359023,58407633,58454693,58492885,58535132,58568536,58600857,58618756,58717319,58906516,58964534,59015452,59062274,59112066,59163291,59281601,59335584,59386148,59420155,59464039,59503618,59537891,59571257,59611833,59720795,59781145,59868938,59905351,59943142,59978808,60117125,60154067,60238633,60399135,60437105,60469341,60504770,60541189,60582360,60611068,60650120,60691876,60737591,60793259,60835324,60891946,60933297,60979063,61026975,61106118,61142605,61176249,61210890,61259740,61289852,61366723,61455893,61499751,61557879,61603364,61650542,61693796,61774847,61854922,61897851,62036600,62080633,62218571,62326957,62415736,62466228,62505033,62553170,62643007,62729177,62766315,62809360,62852046,62891243,62932009,63052883,63100090,63138018,63176279,63209570,63243050,63279973,63312474,63352140,63388941,63466745,63521977,63576758,63621668,63665847,63708260,63751020,63792074,63901256,63966294,64024250,64131281,64170690,64248095,64292701,64379339,64428564,64480791,64538191,64597046,64701727,64753954,64807362,64863640,64905865,64954551,65016121,65061533,65107606,65144099,65181201,65227473,65260961,65307470,65355451,65420321,65489196,65542140,65588561,65633052,65677093,65771454,65815021,65927214,65993887,66050110,66100685,66153061,66211888,66260480,66344358,66390531,66430422,66470510,66506531,66546725,66637027,66678437,66716402,66761130,66847967,66922012,66953084,67031519,67074390,67114547,67149172,67191056,67269804,67305761,67392755,67433972,67477450,67594515,67702988,67770789,67828463,67878098,67925836,67984818,68039921,68095018,68144417,68190111,68227960,68365718,68414104,68519382,68565801,68614019,68650384,68680265,68723253,68759581,68854794,68900867,68949858,69023691,69057667,69106817,69161349,69217713,69285470,69345393,69389174,69451026,69518392,69574387,69612966,69653225,69694535,69750125,69802331,69861550,69905087,69987236,70041576,70083899,70122639,70165386,70206446,70297855,70346493,70395174,70440058,70476910,70516351,70558530,70593591,70726544,70808567,70949501,71011286,71071918,71108369,71164936,71252176,71411682,71473904,71573087,71612115,71656723,71698548,71737002,71781300,71818982,71853904,71925612,71966949,72009597,72043372,72086048,72135257,72196139,72252917,72309170,72488559,72528136,72590339,72635829,72684179,72755136,72873978,72971401,73069243,73121225,73179774,73238227,73283449,73342025,73396825,73516933,73576750,73629746,73691207,73753429,73820545,73949210,74006632,74044153,74089120,74168228,74256608,74306722,74470761,74564659,74603385,74660786,74706730,74738348,75014279,75052914,75101530,75165083,75225585,75385883,75486764,75546439,75635460,75771103,75834363,75914157,75974515,76035734,76134057,76180465,76281852,76335901,76389945,76428815,76477058,76528191,76574265,76622903,76734232,76841562,76910031,77020900,77081723,77136588,77191654,77408761,77477012,77539826,77678273,77739936,77800541,77836459,77875425,77916745,77965404,78004806,78046110,78086573,78127524,78198315,78226348,78267947,78353554,78405659,78503912,78540077,78579132,78622333,78669658,78717949,78763617,78813037,78924517,78966351,79021445,79051759,79082264,79121209,79153733,79186952,79224837,79261557,79292391,79341353,79387936,79477496,79514200,79555005,79595249,79633672,79665247,79706693,79747051,79826743,79864676,79904983,79951653,80030883,80067102,80105784,80185162,80312547,80357904,80405098,80450690,80493461,80532340,80612215,80652469,80682796,80771173,80864856,80904460,80948184,81040885,81086069,81173671,81217578,81263395,81307898,81354359,81436280,81486054,81524224,81561182,81604871,81701951,81803947,81856836,81907632,81954101,82053265,82109979,82224007,82262309,82314409,82358722,82399694,82439576,82493243,82550071,83224831,83269740,83320912,83387752,83440810,83497918,83538911,83601380,83776182,83848978,83913564,83981141,84055510,84234524,84284040,84335453,84381369,84485472,84539420,84581004,84637928,84703340,84766544,84857778,84946970,85083922,85142543,85193727,85245310,85292361,85346632,85436802,85462455,85491665,85538070,85580295,85627175,85673582,85717955,85824802,85866890,85905576,85944107,85996443,86041970,86085543,86123170,86159630,86198755,86237643,86318361,86352859,86380973,86453361,86492011,86524934,86556612,86642225,86739476,86778360,86815799,86847227,86888271,86929497,86976755,87069407,87117897,87154938,87226605,87266546,87337017,87378003,87418645,87457019,87495485,87531283,87603764,87646852,87722249,87758448,87805103,87898302,87984866,88017070,88062471,88107851,88148486,88227192,88272680,88322036,88365214,88407573,88449778,88490213,88541425,88592700,88636875,88680684,88724452,88766993,88815561,88862322,88953463,88999024,89090757,89143714,89180794,89222162,89263591,89308963,89356461,89391160,89462618,89531932,89572340,89605286,89691687,89768727,89814106,89855576,89878417,89920519,90009454,90057758,90099065,90138406,90190929,90235111,90277243,90308979,90342353,90387578,90434888,90475551,90513549,90561690,90602877,90682708,90713648,90826580,90898907,90937051,90983465,91028021,91067481,91104288,91145289,91185485,91222540,91269593,91310822,91341057,91371314,91450693,91559602,91589719,91622472,91673109,91710476,91752355,91796812,91836948,91919030,91965537,92011732,92042721,92126997,92209880,92299767,92331158,92374710,92422133,92464119,92540556,92601768,92646092,92720497,92790405,92835978,92873985,92920058,92953675,92997327,93041240,93078264,93111869,93146567,93178329,93280418,93317290,93351027,93392788,93434062,93575176,93604007,93643221,93676041,93705070,93741544,93783032,93813639,93841222,93897330,93937451,93964637,93995487,94027804,94069733,94105132,94144735,94229530,94301858,94338254,94372098,94414757,94462966,94511926,94596751,94644514,94681738,94725455,94768663,94880129,94914389,94954144,95004997,95044568,95123489,95167562,95204773,95245094,95280165,95318586,95362829,95456581,95502373,95542075,95601463,95651523,95699770,95784181,95825194,95861536,95960583,96004066,96050881,96129853,96177695,96284424,96395336,96536982,96660990,96694295,96732543,96773679,96857204,96996477,97043656,97098189,97161115,97214163,97267936,97317814,97362473,97400041,97514782,97556475,97596360,97637111,97696253,97743100,97787009,97823490,97874036,97921375,97967932,98021728,98060722,98109510,98149309,98230998,98271394,98346923,98372650,98412718,98451542,98488191,98523072,98598400,98624655,98658897,98692434,98771760,98807205,98839942,98872562,98898674,98935537,98972794,99015763,99056533,99130268,99166414,99244873,99317832,99362323,99511793,99548452,99583598,99618168,99655273,99693800,99889146,99941988,99979013,100153115,100266779,100296882,100334872,100370547,100401949,100444736,100514417,100545491,100579095,100604126,100637668,100663806,100693451,100754485,100786248,100811344,100841570,100874935,100953026,101026930,101058351,101089241,101154771,101198983,101233761,101268731,101319026,101358941,101400000,101440390,101482343,101592567,101651870,101689741,101726780,101770768,101806754,101841775,101878924,101911343,101938231,101968067,101999742,102032358,102065780,102133491,102173871,102229740,102278108,102316382,102364744,102430996, respectively;
The positions of the SNP loci on chromosome 16 include: 91841,125757,150839,187676,216742,237453,282890,318413,351517,390810,423750,501638,541821,619483,653739,690552,736447,785075,820888,847980,874855,896901,916328,943656,965589,988348,1003849,1027689,1060684,1086911,1115904,1142383,1171634,1214174,1241146,1261282,1290101,1350475,1383911,1419709,1452568,1491322,1546948,1589083,1638820,1690433,1744736,1802164,1865751,1891218,1919768,1956295,1995371,2028914,2072870,2108330,2144176,2181818,2241568,2296982,2349111,2441501,2492029,2555237,2648651,2734721,2785759,2838395,2880118,2914335,2949272,2983795,3013712,3104636,3134633,3184170,3214964,3249696,3282680,3306602,3357679,3433900,3475699,3511712,3546405,3585026,3633105,3676927,3718387,3760882,3873814,3928713,3968696,3998470,4033012,4068230,4104069,4141619,4177368,4217235,4252647,4283042,4386814,4435357,4479836,4531814,4580599,4622102,4669584,4700525,4734415,4778564,4816532,4859530,4902109,4938727,4973515,5043468,5077865,5116161,5147093,5177282,5205825,5236786,5270521,5298201,5328472,5360351,5393797,5423618,5454823,5483231,5513523,5572974,5597823,5648168,5673958,5702689,5731182,5759269,5784292,5816693,5841952,5870606,5896437,5928709,5958620,5992592,6021830,6053833,6088595,6116226,6137579,6167345,6193147,6260759,6286800,6314330,6377202,6414671,6442805,6472666,6502271,6530050,6556442,6584600,6636967,6659626,6684808,6705112,6727498,6745198,6786048,6811881,6835857,6877186,6898414,6918394,6936288,6995615,7015971,7037868,7060955,7084679,7101976,7122024,7144056,7169407,7194399,7216439,7238357,7255778,7276185,7330246,7363474,7427283,7455781,7477170,7504854,7532073,7558486,7588686,7617135,7642236,7679036,7712321,7744105,7768719,7794894,7817999,7852342,7876499,7913432,7944591,7977691,8004007,8033772,8064771,8093956,8124559,8155821,8179909,8239893,8272084,8300393,8380620,8407937,8434514,8460186,8486397,8539862,8563317,8587714,8608656,8695530,8729275,8754820,8781554,8812192,8840025,8867408,8899358,8933734,8960661,9004266,9047756,9090886,9124265,9155783,9189018,9253101,9316812,9344950,9382576,9417495,9463143,9504839,9539908,9574375,9610404,9644113,9684712,9720593,9757356,9795074,9822323,9866608,9958756,9999005,10043512,10086811,10129861,10161273,10191369,10216343,10249323,10289857,10361294,10394500,10428947,10460838,10500760,10541189,10589144,10620021,10719912,10745264,10770645,10797547,10830285,10870002,10912615,10951268,10994072,11036624,11078338,11161503,11204330,11244513,11281374,11313051,11346725,11374756,11412448,11445116,11474424,11495990,11519750,11550228,11579259,11604073,11735490,11768714,11808806,11897523,11933262,11976653,12019671,12061134,12103297,12148055,12184199,12256742,12301727,12334385,12369300,12408759,12445436,12475876,12506066,12534664,12563957,12600624,12627939,12643387,12653647,12663674,12676983,12707218,12718306,12736903,12780739,12824745,12860232,12895505,12926493,12959260,13023388,13064265,13102532,13137114,13175378,13262039,13383328,13431731,13467613,13504103,13539137,13622857,13659177,13695662,13729075,13761373,13793671,13825081,13860819,13890494,13920635,13949084,13983589,14020218,14063605,14101025,14141090,14198650,14251359,14305715,14354661,14400189,14442098,14494594,14578772,14648112,14716618,14905940,15073850,15134375,15193672,15322619,15483802,15523378,15575217,15684491,15738657,15826666,15902715,15931151,15964476,15992538,16105482,16138136,16172226,16202468,16233172,16284116,16533239,16656155,16711199,16833144,16896909,16968574,17004032,17083641,17132098,17183084,17216798,17254805,17294301,17337931,17418230,17451982,17543747,17594167,17634329,17678363,17761816,17854574,17896338,17930669,17962476,18005668,18051331,18172922,18560560,18756414,18812675,18862735,18921435,18966180,19010838,19055850,19091821,19256345,19364885,19396629,19433528,19468323,19505643,19586519,19619867,19659796,19696326,19800213,19900179,19942348,19998403,20040810,20080896,20129595,20168833,20243036,20320745,20361390,20402499,20440184,20484796,20544825,20584327,20683703,20702166,20815409,20980046,21029171,21081954,21164912,21213721,21312291,21368513,21526234,21573456,21632074,21690785,21741000,21943464,22121428,22179023,22240106,22298579,22355692,22676951,22727922,22778115,22866693,22954196,22992149,23036048,23080584,23138152,23191937,23226779,23316619,23354938,23390443,23436331,23493301,23544030,23642655,23733088,23767736,23805047,23841424,23876111,23980710,24029376,24068414,24105449,24140293,24179839,24226606,24270171,24316408,24354508,24393212,24433191,24473426,24546603,24595676,24680435,24719797,24769659,24813582,24855353,24895361,24926314,24973752,25014740,25048798,25078414,25112883,25152015,25280255,25353155,25403822,25438606,25473865,25509605,25547454,25596150,25633443,25670374,25849960,25883474,25919981,26043084,26094256,26128873,26170711,26216616,26269754,26312895,26350077,26385718,26419178,26463436,26511941,26539214,26573825,26659618,26700301,26735717,26772423,26806392,26869177,26917735,26956118,26983950,27041757,27078072,27122208,27186636,27241591,27290054,27337595,27373918,27419179,27456803,27517671,27582360,27647389,27703328,27761545,27813251,27848418,27887039,27921465,27956950,28001124,28046531,28090032,28139415,28188461,28318440,28497059,28546892,28632288,28828382,29000201,29095155,29141192,29171250,29205137,29241067,29269646,29321467,29600723,29668142,29726787,29799288,29857316,29987520,30049183,30102975,30163101,30351624,30422483,30484937,30533225,30603766,30807352,30877064,30945685,31066380,31119789,31180594,31237920,31287249,31393119,31502313,31656985,31717354,31778628,31831548,31895906,31987360,32096240,32141488,32320816,32370422,32397866,32435047,32454371,32489533,32508390,32523355,32548385,32561314,32581276,32600533,32624685,32655110,32828472,32841687,32849612,33054679,33363242,33390078,33409476,33431732,33465730,33512571,33530016,33539613,33549804,33577288,33653396,33795153,33847255,33867940,33877074,33901010,33913994,33923037,33932498,33936746,33941680,33946608,33951359,33955227,33960341,33964364,33967326,33971708,33975989,33982465,33990230,33999833,34009459,34021286,34181951,34187046,34191396,34196112,34250018,34323737,34411725,34479514,34537981,34615730,34686016,34733429,34877494,34940474,35008134,35134034,35185679,35209177,35225851,35234460,35260139,35272084,35277597,46386366,46387339,46388576,46389518,46390418,46391119,46392044,46392669,46393730,46394658,46395311,46396298,46397815,46400064,46401633,46402661,46404103,46405414,46406359,46407114,46408670,46412758,46418225,46421633,46424928,46428639,46432773,46434716,46437611,46441077,46445156,46455917,46468561,46492084,46499351,46591405,46670363,46739903,46805436,46884719,46961754,47101026,47180705,47264621,47349402,47443315,47522671,47601452,47790949,47852481,47911914,47982740,48066167,48126151,48182447,48248561,48288450,48340111,48392020,48455605,48505550,48553874,48612361,48709270,48763623,48813366,48907238,48964739,49054994,49103627,49148249,49190869,49242751,49338329,49382831,49433692,49482113,49627443,49678416,49718838,49761989,49805099,49915434,49967289,50044980,50171411,50223274,50280791,50362623,50408736,50448592,50482359,50529367,50586357,50639225,50693416,50740933,50783696,50842253,50888539,50929257,50976439,51017019,51053273,51092644,51127708,51170145,51220460,51266155,51310721,51356519,51400034,51529653,51579727,51667916,51719315,51756563,51798584,51845134,51885923,51929864,51967195,52004740,52045056,52222053,52271047,52327958,52388652,52433853,52475272,52523711,52571605,52618534,52695411,52736522,52774891,52818486,52855626,52890877,52922387,52965937,52997936,53085035,53131406,53175289,53302005,53371667,53480294,53536362,53584726,53641884,53808252,53853465,53890078,53939609,53987989,54037867,54074500,54123788,54170680,54209964,54282709,54327613,54363105,54399755,54446771,54482799,54521084,54566139,54638324,54736313,54774735,54814775,54898883,54951636,55001601,55045084,55080544,55119159,55155151,55236020,55271514,55312761,55350601,55429986,55465175,55491704,55550965,55603468,55680320,55721104,55761052,55794301,55815935,55862760,55889566,55927301,55975977,56050349,56090614,56146635,56202800,56256410,56307435,56356830,56397856,56446776,56503814,56558290,56590048,56624343,56658098,56690147,56723619,56771547,56829329,56879276,56919219,56947300,56986914,57016519,57051070,57084915,57124080,57166538,57225357,57325121,57359750,57494947,57542579,57586643,57623118,57657423,57688348,57724311,57760906,57803623,57849737,57921556,57956617,57996809,58042690,58091879,58128627,58179844,58225845,58270402,58311617,58406358,58451810,58490090,58538080,58572203,58618432,58656698,58697907,58737133,58770465,58795244,58823368,58856620,58890657,58926795,58965700,59028947,59076747,59122419,59180121,59219761,59273667,59316341,59364332,59419034,59469678,59565917,59612343,59664619,59710838,59744860,59799521,59835470,59890871,59932608,59987315,60026604,60063804,60119901,60165708,60213431,60344255,60390309,60435662,60535899,60584609,60622562,60709553,60761728,60815505,60864557,60909507,60954151,61007193,61045173,61090649,61125441,61240151,61379275,61451651,61498576,61546692,61599090,61640315,61673337,61721635,61770341,61827610,61901408,61958729,62013561,62062438,62106933,62151275,62191621,62236026,62324643,62366565,62421056,62509719,62555712,62601054,62642194,62685239,62734674,62829634,62877764,62926596,63036260,63079232,63118393,63167486,63263210,63402942,63505108,63602963,63652300,63708990,63751868,63799014,63845434,63896493,63954519,64008590,64056640,64110073,64155866,64200394,64249886,64299122,64345345,64389353,64428631,64472406,64516838,64565151,64664313,64710430,64762037,64812115,64869362,64918767,64958250,65008099,65056145,65114404,65167749,65207827,65257766,65311746,65362881,65421041,65472315,65513291,65556742,65602767,65654209,65703804,65798709,65835899,65874569,65946918,65984700,66024818,66064384,66108028,66154326,66189323,66230188,66276495,66321127,66363039,66452736,66512515,66642747,66705288,66818308,66870932,66926750,66990884,67059547,67128019,67203777,67347031,67417000,67471843,67534795,67603150,67745788,67826422,67896744,68212124,68274851,68334152,68381254,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respectively;
The position of the SNP locus on chromosome 17 comprises: 67859,85376,103775,131064,154378,196014,213975,239479,275604,409155,441590,481187,521423,550621,578180,653339,687843,713341,736927,762451,792999,837680,864462,926315,951644,968807,1004949,1080472,1116410,1142734,1175622,1197782,1224442,1287782,1327909,1396168,1441378,1487488,1522310,1564328,1606435,1647782,1687341,1721157,1754894,1791217,1829252,1944707,1995612,2045273,2093511,2146355,2256513,2290345,2431515,2467204,2521780,2571891,2619698,2659588,2698296,2732896,2773639,2808508,2846365,2917277,3009216,3056544,3104252,3143155,3192409,3222813,3270509,3347952,3422770,3451154,3549470,3615306,3647744,3686982,3728538,3804721,3876433,3956245,3993633,4032167,4106828,4151859,4238152,4291406,4320515,4347702,4377687,4410659,4479159,4551967,4579301,4612249,4686238,4728348,4776655,4869363,4923984,5036740,5141317,5208990,5259656,5297293,5386996,5418660,5450573,5491874,5536715,5660131,5696158,5727675,5762730,5796006,5832753,5863420,5903291,5941868,5982751,6024552,6053549,6091502,6163894,6233223,6277786,6308276,6335844,6366723,6451343,6487497,6535552,6579053,6736935,6843229,6887277,6933638,6967603,7003446,7036354,7077856,7122960,7175269,7217484,7269875,7314435,7362514,7407652,7440984,7479939,7570823,7592412,7636497,7737596,7795832,7849752,7903749,7949434,7986438,8019299,8057572,8243469,8282512,8376954,8470906,8515070,8565937,8609637,8639304,8680314,8789674,8837592,8879910,8923868,8968167,9007824,9086215,9148464,9192895,9234397,9271614,9308611,9384926,9453015,9495392,9541444,9582692,9722150,9755184,9788638,9821400,9888172,9923330,9960805,9996891,10027383,10060500,10125737,10160475,10209661,10302990,10366693,10429261,10474369,10518835,10559868,10599089,10680890,10727677,10764777,10802811,10839109,10917695,10958741,11006970,11053946,11098386,11140892,11182840,11221011,11255602,11298829,11380684,11422446,11461506,11541770,11592928,11632987,11674928,11719552,11759364,11807001,11849285,11893372,11949989,11993876,12043389,12082516,12118496,12164916,12228533,12267219,12343501,12380955,12422308,12462543,12593541,12730917,12767403,12804048,12843555,12876471,12907023,12941953,12973649,13009228,13042365,13084351,13152867,13188333,13227516,13272104,13317978,13358465,13397956,13436579,13468731,13565011,13665400,13783915,13812283,13849340,13892591,13928401,13971982,14020950,14075583,14120776,14167742,14206135,14243542,14282555,14316976,14347431,14376648,14409988,14444117,14477601,14514409,14545523,14574378,14609875,14647771,14680932,14716408,14843663,14881087,14912257,14986973,15026129,15065116,15100053,15146512,15190185,15320898,15359583,15397661,15439334,15549485,15594316,15649490,15694743,15747683,15799743,15847865,15886096,15932130,15986128,16072279,16108288,16208719,16256671,16302806,16344945,16381433,16428657,16538144,16587975,16671587,16733874,16778904,16811940,16847909,16883680,16976800,17032248,17081322,17121700,17167986,17210709,17255437,17298412,17338020,17385701,17426352,17470609,17554652,17611411,17671896,17720391,17822480,17880209,17938784,17990671,18042312,18143254,18192954,18244031,18391153,18514057,18584212,18649366,18714812,18823705,18869330,18920619,19182201,19234205,19295467,19355797,19416037,19461517,19506290,19559529,19602637,19644411,19684364,19732233,19833772,19885584,19933625,19977614,20025022,20086402,20140785,20198024,20260186,20383057,20472753,20584700,20634859,20678002,20721362,20770238,20781085,20811017,20860716,20931020,20972331,21078778,21123845,21168954,21199650,21210252,21219857,21228981,21236657,21253054,21297686,21311771,21320425,21329929,21340156,21351431,21449539,21508593,21528545,21539344,21548956,21555430,21563348,21679794,21723834,21825882,21877857,21910903,21964842,22020219,22121692,22180142,22211547,22232055,22254627,22259230,25265441,25273494,25280134,25286747,25292701,25300052,25307371,25319863,25333491,25376198,25416627,25472795,25517316,25574158,25691319,25733374,25781065,25837690,25900035,25959421,26047713,26085969,26127612,26185418,26245329,26304121,26500298,26569174,26686339,26779795,26827773,26874859,26960896,27085839,27202160,27268937,27329280,27371788,27418161,27465664,27523019,27572412,27624724,27737821,27792855,27902205,27968973,28037506,28092376,28159344,28304334,28381883,28443334,28501530,28544346,28592567,28648643,28701327,28761735,28822666,28922790,28974134,29024318,29057710,29093958,29126324,29177441,29230537,29340171,29401044,29455520,29561462,29662317,29710763,29754641,29797381,29833878,29918817,29961095,30000270,30034299,30068383,30159884,30212931,30263751,30350802,30413626,30464222,30515522,30556500,30602094,30643016,30696346,30828167,30871418,30906133,30951804,31004123,31062733,31186791,31241311,31324295,31357952,31406648,31457902,31501900,31549309,31596781,31639502,31691667,31737580,31776806,31813439,31862275,31905238,31943851,31984300,32022601,32069228,32112868,32155632,32189975,32230085,32275870,32356921,32406410,32487282,32530658,32578860,32615798,32672592,32711241,32751306,32785464,32862852,32903817,32990718,33028341,33066048,33119730,33173469,33241967,33307591,33417971,33468289,33512335,33559987,33607396,33699772,33748837,33782520,33825907,33876202,33917322,33963878,34007719,34060127,34116228,34164603,34268126,34301451,34338758,34378370,34415356,34444443,34474477,34880995,34935670,34986187,35022240,35064768,35143611,35176533,35246689,35329480,35430767,35481477,35593801,35657339,35861600,35909455,35969536,36026807,36065702,36109164,36156125,36193288,36228819,36307980,36399132,36504459,36598626,36698780,36757596,36801837,36849973,36994904,37035719,37075758,37125106,37178429,37221164,37259455,37295052,37365647,37467694,37505887,37557599,37721301,37822416,37870837,37916071,37975214,38028266,38077377,38118752,38249909,38366381,38430592,38494150,38561178,38613809,38662803,38703924,38765380,38816046,38904247,38946965,38986961,39027213,39063788,39100006,39142330,39225785,39265865,39336167,39418252,39458322,39502409,39549162,39594539,39625526,39662169,39705380,39742985,39785042,39829422,39868825,39904681,39941230,39988601,40034172,40089319,40151750,40211546,40266716,40316835,40375425,40439229,40483537,40530376,40569974,40624902,40688809,40739171,40788148,40842689,40907581,40957703,41008752,41063093,41110720,41151947,41197731,41220288,41243581,41252575,41278725,41332900,41387610,41436652,41466108,41546587,41598317,41650012,41698748,41784302,41832148,41882700,41939438,41978635,42017968,42054614,42096980,42141744,42191810,42245347,42329542,42339407,42339999,42373961,42421862,42466043,42574576,42634234,42670660,42711420,42770479,42820385,42876865,42925752,42973517,43017902,43062848,43153389,43252536,43306084,43358566,43405992,43454442,43526947,43578784,43656591,43668226,43704082,43764847,43786236,43807899,43832337,43852605,43890215,43920913,43940825,43964741,44033468,44057181,44081527,44149741,44172327,44196015,44216664,44257783,44277265,44296937,44332970,44345114,44355778,44806862,44869232,44915412,44962046,45056928,45095678,45150655,45195233,45216210,45252379,45291101,45368248,45410386,45466285,45574733,45660388,45717955,45770414,45828235,45870638,45962550,46016084,46065046,46115702,46202514,46252333,46307835,46429444,46538790,46583772,46623054,46675770,46724432,46771369,46818553,46865334,46914755,46964812,47007497,47041601,47090851,47148172,47196790,47235621,47280915,47378766,47426866,47474571,47522145,47563873,47607058,47657098,47724632,47784199,47865604,47979143,48026281,48069009,48102637,48236825,48278549,48323192,48369381,48448035,48490600,48595988,48634553,48683200,48735837,48786462,48830002,48871331,48906801,48957792,49006364,49057267,49114413,49175864,49272257,49367822,49423863,49466523,49499797,49602053,49713772,49749141,49792230,49833866,49880942,49928833,49973249,50017470,50122130,50172676,50236186,50288081,50333958,50372664,50431479,50492438,50653250,50702693,50748782,50791882,50830843,50866238,50943687,50983863,51024305,51077504,51119434,51163545,51209417,51257006,51309790,51399277,51458544,51505435,51598185,51649766,51698866,51795110,51842274,51909966,52019278,52071378,52116729,52166913,52226238,52277081,52334981,52392314,52449912,52506670,52567832,52662935,52695967,52746066,52788660,52838491,52927879,53006654,53049330,53099936,53156810,53301142,53349194,53403565,53445858,53491455,53536867,53585113,53624040,53712589,53758266,53805664,53851237,53896995,53943244,53990908,54034555,54079013,54167267,54381160,54434804,54597745,54641678,54692306,54736372,54775945,54818658,54863210,54906239,54950633,55047615,55095409,55128625,55170834,55208789,55252189,55395557,55440310,55490021,55578149,55618420,55666758,55712238,55760001,55803083,55839278,55876106,55912974,56004757,56066168,56127347,56237810,56277106,56371624,56424185,56493667,56559485,56628915,56683204,56731265,56778271,56839579,56970823,57114769,57250049,57366430,57473166,57523482,57580903,57644265,57777722,57840841,57899687,58004461,58083750,58159784,58221701,58276610,58331208,58392390,58514240,58558658,58601922,58659331,58726771,58786869,58836032,58883651,59010131,59075568,59151946,59224589,59272908,59323043,59371657,59420632,59467908,59511464,59616204,59654453,59761470,59819943,59939018,60057501,60111915,60166759,60207612,60261166,60305765,60358435,60405907,60452799,60508341,60564331,60613846,60677604,60785641,60833833,60883269,60923236,60971749,61024746,61085984,61225605,61297951,61367302,61438714,61517569,61610223,61728063,61787161,61834996,61878317,61927774,61962769,61994968,62022968,62069095,62109315,62155031,62207097,62258828,62306449,62365464,62407380,62505812,62570152,62631069,62721475,62781409,62862921,62977919,63101778,63133071,63208588,63241074,63274263,63315851,63356702,63398040,63439951,63480944,63606208,63647769,63695074,63794637,63858636,63911073,63948693,63973698,64006593,64034478,64066101,64182376,64255926,64285489,64328709,64376069,64412541,64455954,64493956,64536487,64575027,64618971,64660848,64707461,64742272,64787911,64860340,64900825,64944778,64983533,65018284,65115703,65175993,65241398,65288927,65390645,65443089,65489541,65572090,65617668,65654534,65697286,65730404,65862989,65913018,65963947,66012156,66085308,66147296,66180074,66210828,66277401,66326553,66418070,66460604,66502320,66591980,66635610,66714875,66800200,66838520,66893462,66937575,67015279,67069025,67129667,67182688,67232145,67289544,67339779,67386495,67487387,67525322,67572382,67617141,67684476,67856232,67902689,67985947,68041438,68079712,68111227,68154997,68202121,68283969,68320097,68358736,68411577,68536705,68586154,68630337,68676243,68812382,68858685,68930717,68972917,69058994,69095028,69134485,69214718,69338875,69421960,69462277,69501896,69591787,69640764,69687431,69733693,69776449,69825129,69873469,69917056,69955942,70003923,70084273,70131780,70173415,70218748,70266250,70313299,70361434,70398761,70438562,70477615,70518582,70558668,70600834,70679800,70717952,70783009,70823979,70915078,70951930,70993409,71076139,71115694,71146429,71182921,71256855,71333086,71372032,71405960,71484445,71524887,71565338,71690747,71719292,71745951,71821620,71858039,71900067,71944085,71983035,72052420,72088284,72117573,72192553,72228208,72263329,72303055,72342411,72383908,72461868,72531509,72563738,72729658,72831038,72876175,72916895,72963649,73052879,73089882,73177650,73217773,73252006,73294294,73333107,73371658,73415826,73511129,73552185,73582568,73616864,73667033,73719910,73760235,73810937,73901749,73951976,73992275,74037715,74086924,74124287,74173374,74220756,74264876,74348744,74390406,74513758,74703582,74794268,74823282,74860395,74928984,74961266,74997307,75033234,75070231,75105006,75150683,75193796,75234203,75259828,75299182,75377700,75409282,75451145,75487649,75523156,75557354,75583599,75619793,75651395,75686193,75720056,75839050,75876626,75913538,75951065,76010997,76065122,76111972,76219611,76255085,76286229,76320491,76426486,76458740,76481613,76509133,76538199,76564642,76597523,76635474,76676748,76729227,76777487,76817361,76861888,76893135,76961613,77009102,77047937,77088895,77128495,77156381,77189989,77224268,77253136,77307717,77335350,77367542,77396011,77466803,77544850,77676335,77710078,77751983,77801283,77875711,77906477,77945111,77997465,78026895,78063964,78090815,78133098,78175854,78206618,78239532,78271645,78315519,78353008,78395114,78431276,78475988,78524244,78602643,78636736,78668496,78737818,78780759,78814307,78850068,78877248,78908820,78940813,78972192,79006089,79037712,79109033,79139725,79178431,79214894,79256648,79300234,79373883,79452768,79480302,79520132,79629781,79667228,79767023,79929849,79986156,80029460,80065225,80126712,80198007,80239484,80281657,80355153,80399892,80441236,80476541,80516173,80546017,80618562,80743080,80779221,80810037,80841147,80874109,80907283,80955518,80983367,81001170,81021121,81059259,81163152, respectively;
The positions of the SNP loci on chromosome 18 include: 59388,95919,111548,204814,252472,299724,405444,435833,472368,511009,549547,582734,617011,651551,680985,714378,751793,833872,865657,899866,937950,988628,1044792,1088272,1130939,1191418,1234174,1280026,1335265,1436914,1505233,1558812,1593106,1629693,1670445,1717543,1756469,1801797,1842908,1891260,1931066,1957529,1982946,2015601,2060317,2099267,2135466,2169279,2210583,2266798,2297986,2332770,2380157,2418085,2460759,2492386,2563154,2606057,2642951,2678279,2712180,2753411,2830672,2901148,2946448,2991515,3024264,3196356,3242575,3277162,3316176,3350073,3384176,3418464,3455984,3490471,3558116,3599424,3629633,3668061,3700771,3750980,3794396,3844986,3975494,4008599,4053614,4083561,4118444,4161572,4202622,4242887,4280712,4316301,4356352,4388537,4421552,4456681,4499657,4548823,4589283,4629348,4673164,4755369,4791068,4830863,4878847,4933592,4972834,5023457,5100124,5147490,5190861,5219865,5286076,5326955,5364916,5409721,5499830,5548672,5594739,5692313,5731251,5779890,5829705,5873630,5924607,5960068,5993859,6036979,6076906,6119790,6157072,6199459,6250983,6294047,6337489,6388977,6434158,6508305,6545875,6583968,6626549,6662252,6704756,6796110,6847940,6890411,6926854,6963828,6999368,7030450,7065323,7100828,7137816,7168468,7204218,7248346,7282531,7331085,7366739,7403687,7436953,7484216,7520914,7580972,7645003,7687679,7737499,7790899,7840035,7885531,7934969,7977410,8024438,8077858,8135572,8179937,8250662,8298871,8371843,8410768,8445152,8507785,8550999,8630286,8667407,8703302,8739460,8820886,8858422,8892362,8927124,8963003,8994831,9032642,9079763,9132371,9230668,9343873,9390655,9430895,9513023,9705201,9744160,9780938,9816271,9857364,9937814,9967164,10010426,10056339,10104747,10143384,10175158,10214581,10251981,10292881,10321853,10353707,10387068,10462636,10499643,10536793,10643952,10679128,10710530,10741946,10784331,10822428,10863771,10913492,10950506,11031166,11071687,11109550,11157240,11199425,11238106,11276769,11320782,11366783,11408342,11449223,11534183,11578528,11616251,11654176,11729029,11769148,11842887,11874548,11905953,11940799,11972116,12002551,12036610,12075431,12111262,12167953,12221985,12255300,12375871,12414499,12459410,12509095,12598459,12640183,12685321,12734851,12771159,12808140,12854340,12884676,12926924,12970275,13015490,13069796,13160516,13251234,13291698,13390244,13471295,13505686,13542861,13578887,13620294,13672407,13701979,13750551,13836334,13871684,13904668,13939569,13983973,14028993,14065037,14160616,14185530,14223336,14259310,14279150,14301153,14349528,14382275,14411607,14463075,14511944,14610280,14665681,14705908,14740746,14780777,14832424,14866373,14908714,14959300,15002003,15052618,15093211,15133057,15167944,15183336,15209106,15256718,15306073,15348421,15379714,15410313,18513345,18538610,18611243,18677089,18824417,18896030,18974408,19039266,19162853,19280800,19344612,19406847,19468635,19572159,19614316,19646740,19682131,19725197,19777745,19820907,19914189,19964645,20010871,20062034,20106717,20160581,20201911,20246323,20294153,20399435,20514272,20567883,20618082,20660330,20699029,20747183,20845537,20940689,20988701,21077207,21114997,21154943,21314315,21379516,21441302,21501766,21558866,21603805,21637216,21679098,21714182,21752172,21792711,21837165,21882812,21926121,21971165,22006244,22053605,22090217,22126080,22163139,22207589,22247642,22321177,22358076,22402449,22443352,22529054,22578908,22626170,22673354,22714608,22763335,22813136,22869369,22956049,23006011,23054210,23099810,23146123,23242346,23303664,23350992,23401898,23444096,23487306,23534044,23573098,23656489,23707994,23760319,23858237,23901737,23955260,24007502,24101749,24191021,24271378,24405040,24442580,24509663,24547138,24591355,24631358,24675748,24723763,24777533,24841163,24904188,24952522,25004159,25057791,25111040,25158553,25204161,25245308,25301535,25362977,25411535,25441209,25481035,25527707,25566317,25612276,25657876,25700435,25741877,25789269,25832357,25873349,25955510,26016830,26129728,26180690,26229642,26270166,26331734,26379410,26476437,26517205,26618583,26669253,26712899,26759910,26817903,26878802,26936161,26982652,27071828,27193345,27234003,27285624,27333762,27379173,27432956,27491494,27535666,27635308,27674072,27717461,27760901,27829579,27875024,27921679,27959676,27998727,28039282,28073338,28111388,28145428,28186594,28297988,28363713,28421734,28479781,28578506,28615354,28654178,28701462,28767024,28909329,28954225,29001571,29037814,29075164,29123759,29205953,29259129,29310401,29362630,29411722,29457886,29502263,29580120,29625535,29672676,29719151,29766033,29807287,29908792,29967006,30027092,30071388,30121169,30163086,30215033,30269631,30314632,30461178,30503160,30572822,30634652,30754960,30810112,30858466,30881667,30947576,31053378,31104359,31162123,31271619,31327318,31374412,31606097,31668079,31732388,31797312,31869974,31930577,31992108,32202495,32259398,32321794,32414465,32465952,32518790,32608804,32656935,32717380,32760753,32828547,32884268,32938869,32989846,33034175,33129076,33179357,33279657,33321683,33367953,33413127,33462063,33517945,33562227,33617415,33665075,33749371,33788441,33831682,33871081,33920558,33967277,34010589,34059157,34099913,34148356,34193419,34229194,34319157,34378445,34443765,34511406,34572968,34640709,34786089,34935496,34982881,35076342,35173468,35224987,35277848,35326624,35371106,35430332,35482042,35533277,35580083,35628804,35673039,35770485,35819409,35862642,35959232,35998453,36037061,36071951,36118149,36156774,36203841,36250517,36306999,36372225,36426522,36577642,36632661,36692045,36751860,36815582,36925486,36971454,37021457,37082773,37218846,37270472,37335340,37395546,37513230,37571008,37619957,37719317,37777080,37829879,37875781,37957018,37999500,38083812,38136815,38264488,38304682,38353385,38400722,38479732,38621118,38665265,38714499,38765007,38861555,38944999,38989153,39036005,39083827,39131943,39172387,39217734,39265215,39317914,39435052,39471367,39524695,39567322,39625623,39715794,39769815,39823559,39864712,39909507,39952103,39999601,40048135,40151027,40188988,40230147,40274813,40323522,40378436,40437051,40487283,40548565,40602733,40656927,40704169,40746119,40796381,40839329,40908195,41016256,41068078,41118154,41174573,41213971,41296289,41336477,41374612,41416260,41469412,41520932,41568657,41622878,41669617,41727571,41836988,41960274,42028517,42079377,42131942,42255446,42322434,42382532,42440241,42495289,42553406,42612253,42675317,42717857,42803197,42850619,42891844,42945958,42989453,43033082,43072895,43116108,43157248,43202071,43245172,43317899,43354922,43414078,43470463,43522359,43565380,43602266,43648327,43683462,43770384,43858614,43950787,43990769,44046644,44100786,44139122,44178402,44222319,44268448,44352267,44402624,44456958,44515756,44573040,44732687,44866074,44902499,44930359,44964353,45004946,45042148,45082572,45175402,45224608,45266831,45315765,45408465,45453442,45507884,45549383,45592887,45719568,45763646,45810709,45854264,45894890,45941303,45987176,46040789,46095661,46137084,46172186,46213735,46256897,46347806,46391160,46438049,46477521,46518005,46558991,46607563,46666465,46721655,46770186,46818234,46867972,46999755,47088690,47162687,47277903,47312993,47350712,47394484,47465240,47494244,47581748,47648230,47689240,47773812,47861441,47904366,47935056,47978186,48066920,48114256,48208629,48251054,48297672,48402338,48504993,48575389,48645922,48688407,48737039,48785113,48826156,48868170,48914921,48991965,49037316,49077690,49131088,49182219,49256742,49350277,49399322,49453027,49506313,49600611,49647642,49694715,49738276,49776578,49814133,49852379,49942082,49986288,50024503,50063072,50107542,50149178,50230968,50268426,50301737,50321735,50350354,50380636,50415880,50447700,50486644,50530232,50577714,50622457,50664398,50712188,50751464,50803750,50845265,50888006,50923261,50962303,51077313,51125096,51163450,51206454,51244405,51279462,51379795,51413565,51445835,51476420,51551701,51601628,51761523,51798196,51851415,51903607,51941821,51984511,52043127,52254552,52307930,52360903,52414186,52458819,52504027,52589645,52635782,52731414,52782449,52826754,52873317,52919151,52984980,53050646,53107295,53166994,53236441,53300235,53364338,53444123,53508765,53582840,53643430,53745257,53795300,53844726,53890684,53942194,54000943,54051566,54111483,54163188,54213670,54256771,54384751,54436577,54480918,54540833,54595738,54639769,54682714,54718651,54763914,54805560,54892553,54942829,54980364,55026323,55071242,55108340,55150271,55190395,55228396,55301189,55362816,55401130,55465683,55507311,55569942,55611412,55653015,55701407,55766474,55801616,55836472,55875268,55910523,55948271,55987072,56037488,56081444,56115566,56142789,56174075,56213431,56246361,56290754,56339727,56436118,56517062,56621911,56666721,56703742,56743365,56773039,56811418,56849707,56889787,56924093,56965390,57011192,57053442,57096276,57129771,57156576,57186586,57219970,57253742,57291999,57328243,57364900,57401423,57482403,57591651,57622218,57660487,57702877,57775587,57825167,57867955,57960229,58013834,58058844,58142147,58178586,58218003,58259105,58340602,58381591,58427463,58459626,58494527,58607873,58663768,58717021,58776925,58824083,58873843,58926268,58984541,59028063,59088521,59131138,59162574,59251980,59286443,59398268,59445110,59483763,59528677,59573817,59615699,59660996,59737370,59832985,59879919,59938052,59988779,60031599,60072816,60116804,60172958,60261910,60305878,60364693,60425214,60489518,60550417,60603484,60658999,60700381,60745359,60785955,60829901,60880324,60964227,61018788,61067716,61112849,61148323,61182941,61259917,61320300,61369545,61403689,61476025,61514968,61562608,61596107,61635819,61675757,61711727,61751058,61846689,61892130,61937099,61984223,62022104,62057730,62107377,62152269,62187516,62223620,62264706,62341087,62376721,62408556,62452031,62493061,62576119,62623904,62678191,62725477,62781548,62838895,62914955,62992133,63078059,63124847,63170422,63212381,63263763,63310511,63443264,63479822,63621381,63667275,63703619,63746922,63790026,63825103,63860120,63902240,63937888,63985614,64037136,64080077,64123099,64166723,64212650,64263640,64310630,64353624,64458574,64517795,64564246,64621496,64679837,64723260,64748095,64787463,64825765,64900536,64938754,64974571,65006574,65086614,65137673,65193272,65291253,65372423,65412083,65450112,65480447,65517676,65555663,65593373,65624116,65659420,65690353,65764732,65806627,65850253,65883165,65923775,65955669,66006306,66048794,66097726,66142159,66178460,66224777,66265127,66301902,66343048,66514712,66554209,66595454,66640864,66716945,66750950,66793283,66841564,66894766,67015865,67148463,67184251,67296198,67333410,67373076,67412894,67462526,67506204,67540522,67575482,67679255,67729609,67781001,67828096,67913091,67951054,67986588,68027361,68060147,68100624,68138405,68188093,68242682,68292721,68341050,68384491,68438100,68484491,68538385,68591002,68641447,68683153,68724678,68759288,68797188,68826750,68902504,68944790,68989001,69025497,69072475,69116252,69153071,69184208,69268128,69313846,69346106,69450827,69486258,69530906,69585984,69637256,69683902,69732019,69776618,69821739,69867349,69908145,70024078,70058086,70095903,70127144,70162162,70205438,70247019,70302983,70340916,70369184,70401410,70436479,70476621,70509824,70551122,70596106,70666828,70703104,70795151,70879810,70954254,71016910,71054389,71084562,71115861,71154515,71190600,71229942,71269818,71315998,71349599,71390420,71483765,71523024,71561968,71634801,71673195,71714751,71769917,71813194,71847348,71880089,71914831,71945545,72057879,72087217,72170359,72207561,72387595,72441535,72491902,72549405,72611796,72665248,72712233,72766524,72806398,72847210,72886907,72926779,72965896,73012076,73047672,73082414,73125475,73175791,73265469,73303972,73332578,73364465,73481285,73515233,73550726,73598902,73640632,73681011,73721975,73756623,73793176,73855294,73895049,73933801,73979799,74023921,74071514,74113179,74147024,74186642,74229495,74299559,74352127,74382277,74408805,74445142,74481554,74511644,74553361,74599977,74646087,74718957,74751183,74779179,74809870,74843381,74873461,74902311,74936212,74969338,75003154,75031313,75073357,75143045,75174910,75212973,75240377,75281202,75317737,75352927,75375990,75402671,75431402,75505427,75603905,75641491,75678426,75714705,75810132,75847172,75872964,75897618,76039907,76074987,76111881,76134675,76165293,76198058,76236433,76264903,76286186,76318974,76347258,76407696,76432155,76500990,76539421,76571902,76596404,76623622,76652528,76683825,76793550,76827908,76871974,76916902,76961218,77005865,77054354,77117292,77141592,77179374,77210072,77237142,77292331,77318678,77348108,77395780,77431709,77465207,77499980,77530420,77605355,77640867,77676044,77712065,77758837,77887159,77934588, respectively;
The position of the SNP locus on chromosome 19 comprises: 333217,365630,388817,418323,448173,472149,495722,526607,544649,567432,571087,571776,580349,593428,617379,643927,678695,710421,744122,780445,816263,841854,870566,895711,936264,969314,1002883,1030902,1056426,1087734,1158293,1188237,1234532,1285224,1323282,1365440,1404849,1451240,1526881,1609291,1641262,1679466,1714528,1756749,1790855,1836273,1961297,1997375,2030512,2071396,2112839,2190097,2238840,2275079,2321189,2379146,2408486,2440257,2514637,2567544,2596673,2631318,2664358,2703523,2739678,2773952,2815560,2851901,2888304,2944953,2980541,3012557,3048987,3118311,3143155,3170421,3196285,3233942,3278501,3311283,3344960,3424853,3460513,3504829,3548439,3589994,3627489,3672629,3719135,3802531,3838037,3971291,4018052,4053179,4102132,4220969,4255456,4293973,4429155,4475270,4511599,4545141,4586217,4623857,4667234,4717447,4749759,4781471,4818931,4856393,4892175,4958237,5002011,5044085,5078921,5132388,5183322,5214144,5254372,5333645,5370047,5400642,5438935,5477108,5509976,5588826,5653736,5753709,5789854,5830447,5857466,5890385,5937097,5993896,6036286,6083780,6125729,6159014,6197141,6233818,6273862,6309562,6345258,6380891,6416916,6456497,6496351,6534621,6572403,6606814,6663916,6694109,6721842,6765073,6797340,6833072,6868657,6908111,6934430,6965921,6992638,7055106,7099342,7130975,7216669,7273492,7403489,7436596,7472705,7525823,7561410,7607289,7681351,7750637,7771846,7806086,7871045,7919275,7971854,8022228,8120508,8151800,8188436,8219737,8250502,8291672,8325829,8386701,8420456,8466792,8509766,8554718,8595704,8635575,8682594,8769490,8803335,8847934,8922441,8999661,9039166,9078190,9107432,9160244,9193538,9227726,9257120,9337929,9385241,9437763,9532823,9568947,9615168,9707677,9763350,9809820,9853392,9975514,10016711,10063830,10131042,10172327,10221984,10319988,10367122,10488083,10587021,10635196,10675334,10724518,10770783,10929774,11001245,11069229,11115611,11216203,11244430,11279922,11323671,11410141,11454038,11512727,11559777,11611215,11659322,11703012,11748849,11794235,11843260,11925871,11969298,12024649,12075874,12123623,12229149,12283461,12339986,12393130,12443177,12493781,12530471,12558538,12612223,12654503,12714618,12761426,12811424,12871720,12932039,12993354,13051829,13098993,13155947,13227354,13287415,13328058,13368530,13416251,13446966,13482584,13524902,13565165,13613965,13654067,13696683,13735273,13779664,13836935,13877855,13911573,13951830,13999740,14052951,14102388,14153272,14207024,14264490,14322077,14372013,14416055,14454121,14497609,14550295,14590270,14629150,14674499,14716708,14763603,14805519,14851159,14912718,14956197,14992226,15030981,15066245,15101602,15128250,15160909,15195284,15274293,15395111,15465211,15525301,15588280,15632693,15676197,15704229,15737392,15767906,15785815,15803081,15876401,15948112,16003762,16030155,16062599,16113007,16172395,16210756,16260302,16300451,16342214,16413987,16508543,16616586,16679435,16733554,16787913,16830424,16866966,16906241,16964570,17008621,17049767,17093518,17128128,17213558,17293208,17332241,17451631,17601175,17643125,17686657,17730281,17769112,17801502,17842620,17880823,17917753,17949204,17989362,18030309,18080931,18125530,18160426,18188681,18227847,18273632,18317813,18363296,18395112,18441089,18579028,18631256,18715082,18763606,18811879,18853592,18906514,18956480,19015163,19105648,19157258,19202406,19247150,19288885,19343764,19395464,19449719,19506092,19562332,19617584,19676257,19733331,19790136,19839557,19880366,19925478,19987829,20040338,20082137,20115779,20156249,20183404,20225562,20258857,20303068,20390578,20438906,20476088,20578850,20623939,20661024,20695021,20731368,20756848,20787087,20841168,20882249,20914908,20952994,20979882,21013329,21042037,21074329,21114015,21138459,21167817,21214302,21255780,21295067,21384837,21453098,21529560,21562285,21609644,21647791,21684024,21710962,21743324,21757004,21791494,21813402,21829611,21853849,21895749,21938744,21978741,22025850,22075230,22110610,22150192,22199277,22237041,22274262,22363826,22441375,22477174,22508127,22541239,22623385,22708248,22739060,22777553,22809642,22840839,22870903,22905167,22940289,23022284,23057886,23089316,23136441,23229962,23411952,23450164,23477634,23493335,23541279,23582114,23620195,23682249,23744094,23771585,23812093,23841796,23905601,23966340,24044041,24119278,24153503,24184663,24266023,24325906,24371998,24401256,24433047,24468186,24493314,24518388,24538166,24557857,24576799,24595969,27733912,27736631,27739566,27749513,27760169,27793206,27805071,27815966,27830181,27849963,27859151,27870404,27880987,27894037,27910620,27928383,27946876,27965996,27999875,28034173,28065083,28103429,28141101,28186307,28232530,28278119,28304854,28314479,28328080,28348880,28408912,28533064,28552507,28604705,28643579,28679530,28724108,28766232,28829580,28863597,28895224,28927150,28964795,29007174,29087519,29119424,29167973,29289360,29315856,29379241,29488786,29516482,29551199,29590357,29633323,29717108,29811429,29838536,29867634,29895775,29928871,30002164,30037009,30072276,30105427,30149012,30188208,30223721,30336114,30407773,30449011,30497224,30593306,30630116,30674705,30770688,30821354,30876942,30971238,31014949,31067458,31109023,31153836,31257903,31299388,31387275,31436381,31493257,31551716,31604205,31650903,31699205,31751259,31803182,31858112,31898451,31991889,32035320,32128986,32166846,32221206,32264216,32364649,32425030,32477672,32519463,32568315,32691312,32739156,32786725,32836430,32891260,32994913,33034798,33104850,33135215,33167139,33212781,33252036,33300852,33345945,33380038,33453659,33492820,33530517,33620108,33661975,33704113,33740801,33772177,33818481,33862088,33903589,33981813,34032149,34072953,34116970,34156992,34196744,34240287,34280115,34323406,34355502,34400886,34449212,34497620,34538340,34624114,34676982,34730032,34778354,34827027,34880020,34910916,35009953,35050270,35087449,35130010,35175775,35220245,35261114,35317509,35363016,35413262,35495291,35536552,35610585,35654576,35684635,35723501,35765877,35810074,35921908,35960975,36000180,36039845,36085513,36142861,36233470,36281603,36369626,36408197,36452274,36504484,36557627,36600727,36640014,36677710,36757407,36835601,36886380,36929190,36976379,37023044,37128706,37188952,37246594,37299673,37351280,37401804,37444627,37476949,37568536,37658723,37712530,37794753,37848678,37902059,37962374,38024683,38071752,38123980,38172015,38225658,38283126,38348149,38445868,38485272,38527613,38572375,38755864,38801927,38849866,38900309,38941401,38979746,39018917,39059898,39108707,39163969,39209635,39247810,39334673,39420194,39463400,39494342,39554993,39592332,39627619,39669105,39708656,39787649,39846962,39945281,40032132,40111229,40130502,40220764,40254851,40291850,40337715,40369649,40423919,40465733,40507965,40565454,40617533,40662203,40703065,40760408,40876520,40924446,41011261,41153042,41197399,41289586,41331426,41362791,41440669,41481762,41516467,41546731,41587028,41697071,41842875,41880408,41923456,41962076,42010059,42060551,42110221,42154735,42201921,42240621,42284905,42331992,42374397,42422806,42486792,42566314,42650069,42724785,42797959,42922932,42981068,43047387,43106936,43233284,43273404,43324298,43360185,43395723,43430593,43505835,43544190,43579023,43608812,43647965,43685435,43711898,43752588,43786846,43826122,43873376,43919808,43957990,44005061,44042774,44118353,44163307,44219103,44266001,44301400,44339595,44379321,44474275,44509685,44558208,44608072,44650819,44713407,44773450,44862022,44890006,44914769,44961806,44991595,45055451,45096090,45138324,45178307,45329130,45442771,45518223,45568838,45661378,45702063,45746139,45798379,45868478,45950557,45988107,46164875,46208212,46309203,46350551,46396233,46434424,46525572,46568855,46616742,46674304,46718510,46792915,46829213,46878654,46915410,46943030,47004485,47079368,47126548,47173310,47221115,47267825,47305060,47341827,47504601,47544929,47589796,47647212,47702467,47760987,47846396,47932868,47985757,48088780,48131563,48212423,48279789,48320010,48342796,48372766,48489092,48518435,48577047,48603755,48634960,48665886,48702182,48733015,48769804,48800107,48840562,48881876,48926521,48976497,49060804,49121923,49170275,49211068,49328753,49361887,49436513,49469999,49510512,49546270,49589580,49672539,49745407,49772689,49825114,49869197,49901125,49944406,50013045,50052907,50101713,50141504,50199885,50244048,50294150,50343129,50384677,50457915,50486440,50515579,50639592,50690475,50727391,50762026,50802352,50854091,50889814,50916605,50955797,51075229,51110044,51151884,51237200,51268873,51303866,51329272,51353402,51408048,51466447,51498778,51528980,51556369,51598406,51640321,51687117,51732844,51776229,51818413,51857128,51886935,51919502,51964405,51997809,52030370,52135282,52166387,52200895,52234447,52275320,52316365,52388502,52434342,52473606,52515293,52563493,52609099,52690861,52725979,52766726,52807790,52850660,52885421,52919433,52975070,53001952,53027621,53054139,53089016,53149316,53215353,53242581,53278027,53309844,53336209,53399832,53434266,53466424,53499505,53535998,53574937,53640390,53684403,53724825,53827213,53860876,53892073,53922453,53942397,53970930,53994611,54051096,54091144,54120241,54152311,54183704,54235271,54290659,54321535,54356811,54394921,54426191,54462073,54503483,54527012,54558592,54595216,54627915,54692523,54741036,54772569,54801910,54838294,54930431,54964487,55001670,55095273,55123089,55183553,55240313,55258412,55278569,55294329,55325543,55343895,55392814,55428444,55451890,55513741,55539193,55562141,55588006,55625244,55663288,55694651,55784221,55832567,55906182,55944166,55989204,56076673,56115714,56167254,56214410,56250653,56280555,56313579,56342133,56370685,56432444,56461381,56494378,56538150,56567056,56595076,56618186,56686368,56716395,56746678,56770267,56813520,56851100,56932600,56986822,57032495,57077384,57121269,57226464,57256233,57304307,57359343,57403766,57436700,57470132,57502544,57570042,57641887,57675951,57714070,57753640,57792711,57833233,57864599,58004266,58038303,58194647,58247262,58293276,58339578,58381999,58434902,58481265,58523804,58559413,58597968,58629146,58664043,58705080,58747818,58953099,58996147,59035022,59074255, respectively;
The positions of the SNP loci on chromosome 20 include: 76231,126490,154635,194028,226253,278287,311216,344079,368876,402921,443296,485864,528866,564539,598071,632959,670103,735675,762778,793482,821909,885145,946498,986009,1025211,1117419,1163936,1198626,1286677,1332126,1367375,1478465,1518843,1567395,1625050,1659527,1689474,1757124,1805801,1848856,1884817,1921593,1959940,1994963,2034011,2117153,2188753,2221897,2259303,2296223,2394951,2431187,2473130,2552926,2584768,2617701,2645199,2682621,2722259,2765082,2846052,2989384,3065916,3108821,3187733,3224441,3265308,3303225,3377889,3419052,3516425,3556641,3697491,3771651,3802357,3840895,3911486,3994700,4057208,4079949,4110118,4142966,4214235,4332056,4410060,4446349,4486839,4525272,4562141,4594621,4630610,4672269,4703957,4731591,4763378,4791677,4823105,4855407,4899684,5009143,5145693,5187110,5226792,5262051,5290160,5360197,5404150,5435549,5465528,5505764,5539599,5581202,5617855,5647585,5680741,5711154,5742469,5770527,5798080,5830582,5923204,5959423,5993466,6061001,6093749,6128495,6167407,6244211,6319701,6355786,6397127,6430197,6465141,6513729,6558282,6592950,6636978,6670053,6704437,6781950,6816151,6853826,6890074,6929369,7037509,7073713,7117112,7161056,7199354,7238234,7270766,7311413,7350779,7388168,7428907,7458474,7497772,7543082,7586366,7619092,7652465,7688601,7726541,7770976,7856868,7901880,7940440,7983819,8022783,8070295,8112497,8158758,8232408,8269832,8360690,8446700,8489609,8564072,8610425,8648450,8689441,8731871,8765627,8800237,8827539,8860630,8902793,8945875,8992726,9032650,9070147,9118903,9167192,9279233,9322989,9366431,9405829,9495379,9532365,9577066,9622750,9664763,9709701,9749737,9791092,9834706,9876266,9954328,9997794,10031342,10075428,10105067,10146479,10188476,10282188,10323470,10362069,10400753,10436952,10478027,10523896,10583532,10634970,10680221,10727804,10771838,10822368,10865458,10911411,10952823,10986818,11026038,11067917,11188441,11231706,11427959,11473151,11520024,11566458,11607038,11651059,11733680,11845145,11888860,11935024,11975974,12017394,12165437,12205269,12247367,12284535,12336258,12424870,12458016,12498211,12533539,12578226,12613973,12647588,12711939,12745441,12790468,12830215,12871799,12913871,12947955,12984042,13017192,13047557,13080187,13120180,13165406,13210187,13279490,13319869,13362832,13407322,13451006,13501314,13551319,13596877,13694313,13735103,13779964,13825033,13907000,13999548,14051055,14100277,14158220,14257876,14355281,14399677,14449353,14498396,14536808,14630963,14679462,14721834,14802007,14887370,14926333,15008521,15052595,15085365,15124621,15163633,15250804,15295532,15333378,15374019,15411684,15449761,15562411,15598740,15637975,15664481,15738540,15766818,15802476,15877159,15914748,15952124,15987595,16025289,16057952,16095372,16135517,16173543,16202400,16231666,16285161,16332845,16379705,16455165,16493467,16529669,16562284,16600240,16633844,16665236,16701635,16740721,16776513,16853683,16887205,16933588,16970535,17010348,17049049,17133350,17171373,17219647,17263853,17310016,17335528,17371358,17414090,17445288,17478197,17515122,17555887,17594970,17630456,17668196,17739972,17768057,17802070,17836267,17864717,17898450,17934433,17967947,18005708,18040814,18079555,18119044,18162171,18198700,18237120,18276308,18325121,18406931,18447960,18487014,18528254,18563268,18606512,18687154,18765897,18801733,18847381,18889609,18929374,18974548,19012326,19053189,19099554,19141198,19196157,19236526,19277454,19353136,19393323,19427837,19460406,19541114,19582650,19669866,19704554,19781023,19811114,19849409,19879040,19907729,19940732,19974317,20082738,20161816,20201583,20248232,20283768,20329470,20407769,20462193,20531201,20587277,20645845,20757345,20802274,20835517,20881786,20964602,21006074,21048457,21139126,21185516,21237771,21292260,21346241,21403493,21458169,21515160,21560039,21607578,21700286,21754131,21801469,21842421,21889138,21936384,21988792,22037409,22082519,22127647,22172803,22272385,22340617,22382101,22424075,22469934,22507891,22541476,22581413,22629319,22669325,22703424,22741915,22775615,22808975,22836623,22872257,22918468,22962946,23000704,23041581,23079139,23150342,23198152,23241368,23276385,23315371,23354749,23390206,23432310,23461790,23499536,23534722,23607578,23642458,23681920,23716646,23745039,23777061,23805686,23838326,23877201,23917218,23952156,23976159,24006761,24041799,24077481,24117791,24154736,24188891,24218802,24261334,24291580,24405369,24432810,24517982,24563285,24610455,24650409,24681395,24721102,24751833,24820108,24858215,24895108,24928678,24958897,25000886,25046095,25089672,25157288,25195019,25235961,25270291,25307574,25354705,25397157,25435470,25474410,25569523,25662181,25738817,25758324,25836746,25847129,25865078,25878818,25889300,25899613,25909257,25923194,25937033,25952148,25985998,26074197,26087050,26103544,26129447,26140578,26147555,26189930,26205221,26214519,26244864,26254915,26261165,26270948,26277847,26293748,26302279,26310569,29421199,29428898,29437303,29448160,29456999,29469319,29481803,29493172,29510464,29530693,29548020,29560935,29573572,29583014,29588429,29593580,29598742,29605592,29612191,29618839,29624663,29630249,29636064,29645603,29649917,29805106,29814806,29827092,29861881,29959263,30089517,30135216,30177852,30320883,30372106,30423968,30475091,30571286,30659815,30705786,30799856,30845459,30892434,30944258,30992048,31042894,31089109,31147792,31196420,31236411,31278459,31310780,31346952,31379665,31458135,31497052,31541419,31584178,31620690,31656087,31695058,31734430,31775687,31813617,31921951,32011965,32120607,32174542,32283610,32335449,32380914,32438656,32479283,32515393,32607593,32716967,32777258,32835742,32878452,32931890,33087166,33147715,33203720,33302194,33361721,33477248,33524626,33568595,33611208,33647738,33728949,33825157,33869468,33919320,33971876,34012228,34102295,34146742,34180535,34228866,34280309,34411239,34500823,34559513,34610819,34718171,34767821,34832137,34883099,34996454,35047166,35100779,35155478,35204504,35244723,35291989,35347361,35445693,35497799,35589544,35628299,35680126,35731416,35780069,35820867,35859623,35900289,35987638,36054673,36099623,36190375,36224534,36250633,36288025,36324104,36371134,36516792,36559234,36599753,36656066,36757777,36792405,36826793,36874184,36953103,36984610,37012928,37057418,37162165,37212966,37249224,37280490,37318089,37359371,37396120,37432356,37488539,37534369,37584129,37684631,37723807,37771164,37879249,37926387,37974189,38101893,38148112,38191361,38235569,38272282,38305778,38354740,38398518,38454823,38495617,38545582,38598670,38644589,38686712,38820105,38862775,38905667,38954983,38989455,39033223,39079348,39122944,39168525,39214759,39263720,39300665,39343613,39379737,39414995,39456775,39540605,39583952,39669419,39723683,39784220,39886424,39935879,39986753,40134206,40188691,40246386,40297421,40342014,40388422,40430931,40515546,40558187,40599614,40678491,40717079,40754235,40795349,40924773,40968418,41003563,41042770,41077356,41111143,41145681,41185138,41227563,41264229,41309872,41342792,41384278,41424190,41503269,41683466,41724388,41762963,41804309,41846674,41892410,41937455,41983470,42022294,42091071,42130132,42175935,42213013,42287313,42321828,42359295,42536512,42616004,42652072,42724814,42759640,42797013,42835757,42869068,42908169,42951355,42987281,43025595,43062416,43115517,43168828,43224074,43268000,43305163,43342929,43379404,43431368,43480100,43518165,43561588,43605040,43689097,43733565,43774556,43823127,43902809,43931724,43959347,43991255,44028483,44096817,44137620,44211104,44245971,44290985,44338769,44423683,44458998,44495553,44527602,44566343,44642396,44729404,44801943,44843099,44892070,44936481,45023160,45109611,45191364,45223130,45307144,45354185,45385268,45487091,45525464,45559557,45595494,45629822,45661428,45695612,45731955,45796857,45863762,45905651,45948289,46071371,46113217,46145250,46222860,46265090,46298918,46337393,46369908,46397250,46429806,46468915,46496744,46524233,46634480,46672590,46715943,46757521,46792919,46830201,46857755,46890637,46929269,46966590,47004320,47063176,47094250,47130047,47145162,47177304,47211336,47246477,47281853,47320176,47402805,47448380,47494102,47524997,47570114,47625986,47673251,47711285,47749548,47792246,47908663,47951504,47994537,48079726,48125462,48164885,48204416,48272475,48349391,48382914,48412945,48489791,48530225,48563751,48598089,48634713,48674725,48712918,48752490,48868550,48909667,48952832,48992586,49032480,49067246,49101677,49137446,49229473,49299853,49339418,49379064,49409173,49489386,49530536,49575021,49613583,49655483,49695511,49736430,49776438,49807995,49852451,49887639,49927240,50000969,50027059,50135529,50173331,50208036,50246869,50273045,50305063,50338810,50398662,50433347,50497125,50529156,50569252,50604076,50641692,50676763,50711018,50740423,50779420,50820444,50868916,50913176,50958166,51001483,51036785,51077117,51134889,51179082,51231557,51266440,51303915,51372101,51415799,51460221,51554687,51711538,51748950,51787072,51822731,51862148,51906004,51946605,51984117,52027231,52107618,52142498,52206594,52247621,52315893,52385470,52419641,52451654,52478264,52491227,52526261,52560758,52598078,52630442,52730640,52793352,52822006,52895224,52926083,52960114,53004574,53041094,53078023,53156696,53195916,53262368,53289631,53316146,53347625,53390951,53431044,53461702,53495179,53528705,53562594,53597495,53629833,53665450,53690053,53714627,53756881,53788165,53822173,53859097,53893219,53928270,53973293,54013142,54091286,54124517,54151354,54187005,54217637,54270300,54301289,54334796,54368355,54397792,54432293,54503042,54540328,54574793,54626600,54671792,54716125,54824557,54855648,54887180,54967460,55008092,55092245,55130395,55166534,55206557,55241958,55276679,55307372,55345717,55380506,55417746,55451437,55478220,55511788,55542429,55579120,55609158,55640387,55669341,55734779,55767965,55802055,55843309,55893741,55934205,55974779,56008212,56042205,56074907,56113304,56146106,56180285,56285845,56326759,56365171,56404310,56433823,56466688,56497277,56527638,56633481,56708705,56745038,56772887,56815554,56858907,56898134,56980800,57021541,57101616,57139066,57172970,57206736,57290484,57330456,57368464,57412067,57456914,57493824,57539105,57572709,57616974,57705485,57793382,57877621,57917108,57957238,57984718,58018437,58057317,58090071,58133512,58164790,58206004,58283170,58320369,58353445,58389899,58435901,58484630,58538862,58582415,58662650,58688046,58723958,58760520,58797648,58835470,58935468,58979726,59024655,59061433,59102674,59197174,59238429,59297791,59329911,59360715,59399952,59437716,59471696,59507067,59545213,59582890,59616556,59645097,59676675,59708314,59749781,59783700,59818916,59884435,59912480,59942013,59968829,60003841,60032848,60076205,60110021,60140297,60167790,60205058,60234142,60293382,60318823,60352065,60376752,60412032,60443445,60501137,60522482,60554263,60585979,60689943,60728912,60758143,60789134,60832315,60869733,60957331,60984143,61018383,61051373,61087771,61168787,61190180,61342777,61371078,61403330,61437448,61465614,61496338,61534794,61573811,61607275,61669558,61706197,61734711,61765988,61847068,61880462,61919444,61981605,61998174,62028764,62063592,62095147,62127584,62190235,62216523,62241284,62275684,62308971,62343164,62402403,62437656,62470518,62593837,62633096,62680560,62723006,62756897,62770113,62833410,62872504,62908917, respectively;
The positions of the SNP loci on chromosome 21 include: 9416284,9572394,9651138,9677401,9832928,9849330,9863658,9893658,9970657,10012454,10086615,10381158,10423379,10476027,10550411,10612394,10702657,10707253,10712760,10716977,10722209,10727842,10735069,10744581,10750951,10763444,10774667,10785259,10797426,10810260,10841061,10858412,10886173,10900557,10930816,10965010,10999871,11029624,11039583,11046937,11055963,11061900,11066736,11072874,11078949,11085032,11092625,11100487,11109037,11127556,11133391,11139752,11155287,11186474,14342793,14350725,14359615,14368228,14390732,14412607,14473305,14561413,14636381,14683989,14735691,14752721,14778628,14844013,14946397,15062577,15229407,15247788,15266036,15288836,15314609,15336061,15359883,15403323,15438560,15457131,15483570,15530499,15607071,15631164,15655879,15692235,15719061,15791600,15865732,15936132,15964119,16002707,16041439,16097382,16133904,16162316,16195204,16242611,16292880,16345459,16383824,16427140,16498243,16535340,16580580,16780693,16814655,16895833,16935979,17016189,17053737,17160587,17219626,17272621,17332040,17372295,17411568,17467068,17522932,17599603,17670740,17746503,17779717,17821761,17860640,17905657,17995449,18063466,18110478,18154879,18196761,18231769,18266662,18301488,18335180,18375287,18407931,18479249,18560660,18626747,18669299,18794776,18826103,18857579,18896246,18931996,19005148,19050836,19082650,19126114,19267585,19339772,19422865,19499647,19564149,19612107,19645612,19816402,19864918,19904121,19942993,19977568,20024746,20065362,20105756,20139532,20179718,20212168,20241238,20284399,20317173,20354867,20426661,20462960,20508381,20549131,20591768,20638853,20682862,20721513,20773035,20823979,20904052,20969012,21006237,21050623,21088065,21128712,21176350,21211922,21243867,21286764,21368653,21447155,21527063,21575280,21618216,21663474,21695594,21839242,21893779,21966649,22122519,22151343,22193748,22233898,22351225,22382654,22417847,22481258,22510510,22557344,22596660,22635834,22710878,22751582,22793671,22864581,22940247,22981624,23022267,23061004,23227031,23274075,23308230,23347227,23380159,23424863,23480036,23538540,23638314,23751023,23829508,23874595,23925128,23952969,23996052,24029647,24066559,24102973,24150495,24220855,24261926,24313144,24363436,24405219,24444768,24481855,24565963,24600149,24640948,24679281,24718762,24760134,24797757,24828283,24865272,24905803,24935729,24971650,25003931,25049198,25093869,25187933,25218455,25251387,25284069,25322824,25358203,25389929,25414932,25439151,25460946,25485874,25513533,25546742,25579252,25627810,25712819,25753316,25803548,25846856,25889287,26017036,26054675,26095504,26169765,26210572,26257674,26305241,26349805,26392038,26446909,26504207,26552889,26591545,26684805,26799570,26847893,26904460,27029994,27118846,27155126,27182334,27212854,27249438,27317608,27348258,27377350,27405308,27489236,27533710,27573949,27622881,27661345,27697893,27742979,27786815,27834624,27935606,27979861,28015738,28124222,28169135,28210693,28248386,28293795,28341064,28382377,28449564,28490550,28558901,28591649,28629740,28669825,28710016,28745624,28786756,28819930,28864855,28905881,28959524,28999877,29121129,29168505,29209183,29248875,29297616,29335537,29382257,29426941,29457416,29487089,29514609,29554601,29592650,29702063,29738422,29768805,29801621,29834691,29917879,29953927,30031175,30076890,30109148,30137916,30178277,30219973,30251205,30338456,30384933,30433276,30628120,30686902,30737237,30785629,30835483,30865729,30967878,31004309,31045052,31091928,31135490,31177557,31218381,31248431,31290765,31330769,31418192,31509099,31545508,31589081,31621684,31662152,31703987,31744287,31790514,31833544,31883080,31979790,32037484,32075985,32104291,32150431,32196671,32235858,32378145,32421417,32449036,32490292,32568980,32603457,32650871,32698392,32737704,32771597,32806714,32843665,32919790,32962502,33000955,33043732,33094040,33143483,33181112,33224196,33255472,33329332,33360859,33427300,33464397,33499611,33542897,33580136,33631793,33676558,33719434,33766594,33804929,33838266,33880318,33971244,34022261,34141593,34187695,34245761,34338366,34377552,34422353,34575721,34644897,34672938,34708622,34829570,34872238,34930179,34988002,35048741,35105880,35163031,35221267,35295810,35340999,35376025,35414404,35538892,35580048,35625529,35674046,35720456,35754839,35786524,35826535,35862484,35929628,35966757,36011975,36050247,36133848,36188764,36234671,36279819,36323507,36447091,36525506,36566379,36638306,36678343,36886779,36959163,37001408,37031102,37071840,37116730,37177059,37290025,37357822,37442116,37479914,37514392,37548398,37624774,37662367,37768962,37816000,37848603,37920907,37956263,38003532,38040461,38081966,38126275,38170033,38214157,38254177,38345727,38561918,38602760,38651907,38688804,38725582,38773784,38862376,38910581,38958104,38996789,39035897,39064093,39102048,39145410,39238945,39285456,39383865,39434993,39539266,39589945,39634109,39673704,39717703,39807036,39844788,39897807,39937289,39974870,40014437,40060268,40152372,40190412,40225683,40260709,40298609,40337613,40401135,40432520,40499915,40544464,40580451,40619656,40657169,40690397,40723011,40764066,40809028,40855439,40893960,40924056,40955751,40988612,41062838,41096818,41127172,41155350,41190444,41256058,41287202,41323477,41351895,41383840,41424162,41497349,41532739,41565047,41596831,41637122,41671275,41717537,41838994,41904600,41935061,41994797,42018997,42068138,42105800,42141147,42180961,42215370,42253855,42288948,42324573,42373258,42474210,42508856,42548719,42637222,42678029,42721722,42761102,42802447,42831593,42941502,43028392,43069311,43101272,43132579,43161805,43225714,43255908,43288345,43327676,43399915,43443570,43470695,43498930,43532853,43597934,43637349,43679554,43715047,43752969,43782430,43848186,43884666,43931364,43972478,43995088,44026272,44061266,44095690,44136884,44173148,44206616,44249381,44279393,44385887,44415885,44453703,44479324,44514315,44566869,44601086,44764719,44798699,44830979,44868960,44919668,45123364,45163060,45196121,45229577,45260610,45298501,45342204,45387665,45430904,45482041,45572061,45608071,45635719,45669863,45734229,45772635,45812326,45839498,45869515,45916235,45952553,45989795,46013349,46045124,46075092,46106397,46138768,46171571,46205464,46244765,46268652,46330487,46362691,46393533,46412027,46441829,46475940,46523623,46566470,46614186,46657243,46686708,46764460,46795235,46827478,46904833,46928976,46958586,47165936,47213476,47252759,47291103,47318259,47344494,47374985,47430931,47485424,47510972,47544453,47561218,47613175,47651023,47687254,47713070,47746649,47785323,47817563,47842336,47878671,47917664,47955559,47997129,48033490, respectively;
The position of the SNP locus on chromosome 22 comprises: 16057288,16242751,16444659,16620586,16852685,16856595,16868364,16885814,16903325,16918399,16939393,16956851,17013924,17085746,17125738,17194240,17237414,17333650,17357915,17372703,17381841,17396176,17430558,17475942,17504077,17535049,17573272,17607174,17665135,17774161,17808961,17841198,17877906,17908596,17936616,18076467,18106823,18135129,18174781,18211329,18277438,18311300,18432033,18458035,18483013,18515631,18553028,18585820,18657355,18778156,18875965,18883566,18905328,18943415,18974986,19051371,19086904,19163047,19199403,19247209,19291766,19404733,19449571,19496423,19609106,19640667,19678313,19757010,19793593,19844234,19882630,19911619,19941947,19972935,20018969,20059344,20103462,20149985,20223508,20629154,20713559,20753223,20783721,20830422,20874540,20986448,21062296,21109206,21150840,21233783,21272897,21345091,21375994,21419163,21451951,21575930,21928597,22020483,22055589,22093837,22139208,22183980,22367697,22400049,22435054,22463754,22489560,22518338,22550401,22572034,22599953,22624656,22656699,22687958,22709354,22729306,22783396,22916243,22947837,22983489,23047893,23066978,23100385,23125650,23166939,23206697,23236406,23297693,23340805,23391131,23451356,23493873,23530961,23602419,23669372,23701581,23762264,23790919,23818837,23846492,23900837,23970897,24000068,24079724,24117959,24149768,24177636,24212056,24240089,24269519,24324016,24372494,24496099,24562398,24643540,24688968,24736280,24842098,24891166,24931625,24979004,25034777,25072287,25153606,25183877,25218912,25251671,25284552,25317044,25354656,25390270,25444874,25483767,25523876,25564047,25602790,25631756,25660119,25729594,25761936,25804453,25832687,25909119,25974887,26017001,26078646,26168894,26228942,26265357,26334249,26380596,26409140,26450986,26493132,26584585,26662382,26697195,26730293,26793073,26828619,26865058,26906216,26945788,26982424,27028313,27093674,27176574,27215701,27248223,27284036,27319646,27349278,27385279,27483480,27505558,27541354,27574903,27615461,27648408,27718759,27751796,27784836,27815619,27855798,27891917,27925722,27961612,27999372,28029538,28061578,28099616,28141113,28220424,28341053,28395422,28453818,28521553,28588692,28655314,28721065,28782960,28851868,28908195,28975913,29036303,29091443,29128013,29168360,29209728,29249525,29295898,29351034,29409445,29456360,29490668,29522251,29555480,29636985,29678569,29731755,29777146,29889650,29934120,29973634,30018643,30068570,30121500,30167931,30216900,30255462,30296059,30337335,30422468,30585746,30684787,30740157,30843355,30880262,30917825,30957832,31002638,31063617,31159625,31205912,31254555,31369636,31423708,31466685,31508195,31647724,31694861,31844293,31882278,32017509,32108997,32160708,32214274,32259855,32301770,32382309,32470485,32526658,32568831,32599540,32641683,32681058,32706509,32757417,32783210,32847759,32884942,32921697,32952699,32984761,33017539,33057006,33118615,33158093,33182004,33218431,33263931,33299596,33348284,33465413,33510161,33543050,33579610,33604051,33650660,33687940,33763746,33842875,33880290,33952694,33992541,34031333,34070819,34107919,34145831,34180801,34217687,34290257,34370403,34540680,34573465,34642027,34683829,34725083,34844073,34881535,34909133,34945097,34980085,35022040,35059183,35099134,35143901,35228878,35308678,35345623,35381546,35455664,35488540,35531612,35562148,35635864,35679787,35720198,35758742,35793266,35830470,35860563,35893900,35929749,35967818,36031861,36101450,36131158,36265616,36326172,36382858,36438869,36478989,36522134,36559476,36584260,36615706,36654145,36730947,36779064,36854851,36889485,36922997,36953965,36987577,37024359,37061519,37098913,37133413,37171795,37207484,37241090,37273205,37345923,37406778,37450840,37490714,37522525,37591373,37620663,37648151,37681968,37721217,37752697,37792590,37825180,37870939,37912754,37988349,38031491,38072876,38156518,38196474,38240841,38294830,38349525,38402956,38496556,38528391,38563541,38596646,38635486,38680816,38772004,38819028,38860740,38907849,38964460,39062007,39111812,39160569,39204683,39247333,39286923,39322400,39360018,39395101,39428958,39469000,39499072,39575931,39607698,39642338,39677317,39712936,39744254,39778327,39817348,39863980,39909121,39951454,40029845,40075834,40124460,40180308,40373570,40414607,40507074,40549566,40603363,40650617,40712637,40759034,40813063,40862885,40915813,40972769,41028308,41076141,41204323,41245806,41307588,41363730,41408697,41448195,41494994,41536320,41584928,41627073,41669738,41718696,41771306,41815305,41855949,41911621,41962626,42013434,42051167,42091013,42134786,42175283,42221951,42266168,42362560,42413978,42456140,42501630,42530096,42557991,42706035,42753014,42820191,42865011,42905119,42939245,42972441,43016259,43045458,43075948,43100238,43129179,43162286,43191404,43227257,43259338,43295560,43332917,43372780,43415273,43440400,43507163,43543462,43570068,43595931,43631079,43672183,43702268,43839229,43872598,43924876,44013348,44056176,44102016,44202556,44285069,44316789,44353447,44389400,44428015,44471389,44506233,44624734,44653289,44678726,44706814,44750693,44784753,44816777,44844243,44927476,44951812,44992632,45023250,45055584,45084259,45120084,45142177,45226519,45253953,45298174,45332310,45371568,45439659,45504764,45537472,45572370,45606511,45638165,45696672,45736087,45776576,45817438,45855171,45900865,45933740,46000105,46037048,46084192,46136298,46178991,46334281,46364150,46405845,46450616,46499702,46533658,46572063,46690141,46730215,46763822,46793783,46829197,46861091,46891122,46919495,46949538,46978509,47004179,47067547,47100250,47133580,47167510,47207475,47248289,47282589,47376559,47413929,47445095,47474013,47510793,47547265,47571342,47603829,47642162,47677211,47745086,47770651,47800611,47831067,47865923,47902521,47939486,47976253,48006248,48042907,48073595,48104604,48135383,48172174,48207318,48239482,48309921,48335187,48374222,48411777,48442453,48476049,48511936,48549166,48581558,48615590,48646439,48680069,48706642,48734161,48757226,48784485,48861523,48969991,49003154,49028413,49050237,49068935,49090646,49114275,49136285,49165390,49190094,49215182,49268705,49298491,49322938,49340692,49355550,49375523,49405431,49429681,49459958,49482299,49507434,49529438,49551620,49593552,49618978,49645065,49668630,49691071,49709694,49740616,49765146,49801544,49853908,49887600,49916560,49948433,49985751,50022958,50056891,50084219,50114083,50145334,50182704,50219119,50258016,50294378,50322324,50458283,50487316,50510849,50546418,50576193,50604854,50643085,50678701,50715029,50760505,50820836,50893806,50930802,50964018,50997145,51064169,51096831,51181563, respectively;
The positions of the SNP sites on the X chromosome include: 2247736,2723056,2726647,2772772,2818489,2853865,2925833,3050788,3106679,3156087,3221937,3264863,3379301,3461933,3528085,3581242,3628842,3741069,3919914,3974752,4035440,4112317,4175504,4241143,4426343,4596138,4659861,4797471,5024589,5076991,5243292,5336596,5408033,5660963,5778980,5920769,5996660,6075482,6234899,6314024,6407568,6770687,6850716,6944028,7038170,7139497,7489784,7599241,7858400,8172307,8271791,8357913,8498794,8583601,8878203,8991176,9098482,9218998,9292510,9374087,9421049,9495259,9589148,9679669,9753062,9836993,9913522,9982928,10088483,10173531,10269804,10365923,10520521,10656768,11050645,11229398,11364558,11497575,11604276,11709018,11825275,11935961,12218532,12313140,12488668,12570439,12631386,12730782,12802363,12885578,12949971,13022987,13114747,13234580,13618680,13815840,13970038,14079164,14185658,14325565,14444879,14581627,14663000,14864661,14978036,15069346,15193414,15360037,15436616,15529726,15621753,15727488,15819715,15923627,16038611,16170722,16249951,16555776,16700683,17105212,17223673,17366234,17508025,17777984,17917292,18072162,18199514,18339898,18493996,18671639,18763318,18852335,19100354,19300218,19542285,19770845,19894793,20045436,20175657,20312827,20428942,20558145,20680893,20788936,20997004,21132439,21277318,21458070,21665268,21809203,21917207,22005458,22087152,22179283,22259792,22394838,22537140,22618265,22700424,22779144,22910949,22992387,23073087,23163525,23230758,23298463,23387866,23472193,23560462,23645556,23908073,24004215,24086475,24179254,24340662,24566424,24647839,24754655,25014016,25135691,25193978,25303466,25581514,25693805,25778619,25859671,25941333,26152681,26239589,26355789,26462840,26584392,26714878,26823884,26922358,27000293,27075302,27161613,27256177,27449542,27600689,27676641,27767127,27882754,28001188,28321826,28450873,28533665,28658580,28769283,28850298,28949893,29075877,29167569,29268015,29398264,29796253,29904705,30145792,30250323,30347137,30448975,30538701,30635150,30801815,30923357,31008479,31092052,31242967,31323365,31481840,31574895,31687218,31774154,31854956,32026645,32096656,32257197,32322111,32395073,32468849,32539807,32662118,32739771,32888876,32962172,33028279,33089243,33160529,33254721,33355913,33448052,33555648,33648477,33762633,33863914,34061389,34160077,34265223,34382963,34462232,34651771,34744640,34825215,34988299,35065946,35314050,35526044,35620221,35822378,36141199,36369132,36473338,36600315,36687987,36788407,37039205,37212354,37416876,37530619,37737278,37827731,37913861,38021993,38133578,38262956,38333236,38399317,38509179,38625654,38748735,38861559,38973645,39105874,39231086,39354714,39681250,39780781,39888989,40001908,40101255,40203306,40285704,40374658,40457146,40657954,40768393,41035059,41127924,41284554,41361176,41481418,41643603,41795650,41916490,42133876,42289767,42565976,42670217,42784349,42880337,42979192,43136772,43408101,43636014,43765185,43877162,43982659,44226439,44321963,44481995,44789114,44905277,45034831,45245165,45508861,45601943,45957656,46088273,46193261,46285456,46400213,46528805,46642066,46791335,47174276,47498518,47625257,47730342,48014034,48149309,48457737,48566194,48732343,48875619,48980062,49071964,49161970,49496558,49630637,49758011,49897658,50451821,50671082,50783179,50910987,51178055,51303187,51434857,51618721,51745507,52569824,52680983,52891880,53097678,53218927,53356380,53513626,53910400,54095207,54426674,54541444,54771344,54893413,55122411,55238639,55341561,55476740,55652971,55731858,55850745,55912007,56007046,56093292,56184351,56482346,56599025,56680500,56780691,56949803,57077761,57274779,57369157,57475006,57557872,57812382,57923990,58064534,58139245,58258276,58359259,58419799,58460132,58487396,58516652,58546967,58562693,61686636,61727367,61731050,61734450,61756619,61774199,61800641,61817387,61837430,61853319,61872827,61886975,61915274,61960631,62085069,62197802,62411198,62954218,63137120,63271012,63355773,63435940,63579784,63700053,63767963,63975278,64091357,64219476,64362016,64438517,64671405,64815536,64948323,65087342,65308182,65416087,65521139,65601657,65676157,65761831,65862003,65986311,66127648,66255263,66351161,66457015,66566096,66681845,66855958,66983983,67079600,67177932,67408506,67653014,67787331,67894900,67993236,68090762,68189219,68315938,68408301,68509969,68596458,68697588,68832306,68959774,69175270,69287323,69395699,69508744,69640003,69865285,69990305,70100630,70178413,70362956,70438608,70691198,70846383,71129266,71369602,71472881,71562740,71739209,71897470,72274506,72397531,72499787,72715551,73098352,73231553,73359492,73487125,73582627,73699600,73840426,73983025,74154287,74288514,74400345,74530888,74621195,74729354,74834441,74940143,75063329,75106748,75172103,75324037,75410927,75489592,75591888,75730864,75882445,75943064,75996534,76070979,76115897,76171980,76257806,76267483,76412601,76515277,76831954,76976340,77158147,77343278,77482778,77614005,77725648,77798547,77931072,78153391,78256387,78374905,78478141,78574081,78629853,78720152,78805965,78905411,78970775,79052174,79097882,79143017,79219879,79348195,79445710,79561287,79715551,79792940,80043138,80343181,80480650,80785698,80899134,81042877,81138977,81251722,81358449,81479189,81644360,81745962,81832970,81939541,82131129,82236358,82329314,82435241,82573698,82716544,82866911,82999681,83138950,83270093,83377359,83509098,83627869,83713475,83789693,83867298,83971373,84222236,84332857,84424643,84542343,84660945,84823662,84883515,84955255,85018323,85125425,85215758,85324321,85392150,85548953,85619905,85738246,85820881,85912303,86097156,86174383,86253775,86330673,86393797,86499898,86569710,86632077,86707786,86793474,86874220,87047738,87118741,87285187,87383275,87468387,87531726,87572988,87622982,87681846,87740705,87796983,87891061,87984100,88174381,88264737,88346834,88419781,88514421,88721524,88786664,88847614,88897073,89028813,89102107,89181362,89247530,89335584,89400707,89463092,89518354,89578272,89637861,89688777,89760303,89820040,89879125,89937707,90003220,90069456,90133349,90209297,90273306,90335061,90484785,90580348,90687207,90828688,90956906,91187700,91324946,91363755,91527762,91575474,91625647,91758818,91818708,91947974,92007907,92083330,92133157,92200854,92252891,92304557,92353261,92413353,92685644,92752089,92825885,93060122,93167552,93264076,93346427,93423002,93596095,93780313,93897106,94014903,94097292,94189382,94282356,94375081,94455637,94655782,94777039,94892333,94993102,95092667,95239914,95319527,95540353,95607330,95718391,95815227,95903084,96014318,96090793,96203190,96339699,96434755,96529410,96647727,96784023,96892106,97209636,97306908,97409778,97531050,97777683,97880585,97993450,98112677,98244967,98489683,98634884,98768317,98883862,99030999,99132620,99228188,99333238,99561814,99764645,99882543,99971352,100071301,100347118,100435355,100534438,100609438,100673586,100791617,100897984,101018561,101217305,101303220,101399025,101923418,102047079,102167613,102297849,102395978,102493441,102609488,102739586,102868950,102979095,103047606,103137615,103531511,103687472,103838055,103978079,104127507,104252681,104565350,104685898,104830130,104946614,105225843,105344924,105490973,105661527,105958939,106256388,106362430,106480937,106620310,106780618,106910255,107026805,107162475,107284339,107425309,107545662,107763538,107845115,107929301,108037290,108111049,108293470,108399575,108491687,108616957,108744008,108858688,109005318,109095000,109201721,109329902,109508834,109710502,109816218,109912294,110003600,110138513,110285720,110422204,110559643,110697306,110851322,111012035,111242944,111356910,111462376,111534036,111636471,111734920,111932083,112067381,112256579,112366947,112452147,112553469,112657423,112770310,112864203,112941009,113059660,113147877,113261156,113349619,113481339,113624829,113741944,113861510,113968909,114061198,114244548,114605041,114709751,114789361,114891664,115014610,115100792,115223760,115311011,115397111,115481604,115775851,115863438,115940364,116001898,116095179,116168464,116231302,116457865,116528251,116587390,116651039,116754839,116820686,116905279,117105512,117216102,117368703,117449641,117526021,117688822,117809414,117969872,118041750,118121382,118206620,118495542,118617649,118681825,118756484,118840392,118892474,118954012,119029054,119104380,119406962,119591135,119818275,120005338,120344340,120580478,120693514,120940070,121030445,121128552,121219659,121312708,121475780,121556308,121819527,121896909,121980159,122163503,122265252,122360725,122473332,122584172,122696559,122812180,122868557,122919621,122996252,123273413,123421001,123518852,123711355,123823890,124003799,124124103,124222516,124306181,124405240,124495416,124585335,124661034,124736106,124824611,124940100,125055100,125146744,125238194,125435231,125507565,125606370,125680230,126072482,126182527,126371135,126455182,126564476,126665727,126748679,126809636,126909753,127169217,127276021,127376997,127494763,127638011,127873425,127959242,128052297,128134757,128246124,128347294,128425453,128518182,128636472,128743228,128903472,129560425,129644583,129751234,130123120,130255991,130380462,130492122,130604660,130716953,130847166,131026517,131131827,131388718,131542498,131719473,132092023,132219575,132367014,132610554,133001689,133165103,133492339,133596418,133662605,133772306,133919538,134166632,134669316,134786450,134975438,135096039,135199177,135305804,135458848,135565593,135805503,135918726,136012789,136130499,136246693,136359020,136446829,136747199,136851415,136967494,137180011,137293810,137384309,137484331,137577916,137690086,137832884,138151701,138255170,138330926,138424492,138600830,138669578,138759178,139086172,139155386,139330678,139636645,139721973,139894872,139977743,140050689,140269630,140358350,140442074,140506439,140697174,140780527,140930467,141086936,141154190,141216789,141287277,141362523,141447156,141614525,141679795,141740128,141811816,141899797,141975671,142159350,142265721,142347861,142445351,142562505,142632686,142708882,142789028,142867071,142958662,143051956,143153877,143340207,143407745,143735678,143819163,143917456,144009483,144087996,144166886,144246695,144298395,144452817,144556105,144646529,144732712,144833007,144993077,145077839,145163584,145341136,145422489,145505768,145584154,145649530,145738385,145978838,146060061,146142150,146246173,146346011,146453158,146633426,146712451,146923549,147434007,147547796,147662555,148007563,148258888,148369123,148485130,148573408,148699077,148887258,149135222,149275091,149399646,149513612,149618774,149702027,149936269,150048256,150126802,150274333,150349871,150425915,150506484,150683157,150779555,150849025,150926313,151087610,151166990,151261356,151330581,151424101,151533532,151648050,151907964,152044451,152144399,152210481,152485061,152602717,152860457,152933009,153008083,153238494,153358913,153630255,153708719,153780401,153968860,154081055,154183650,154311568,154456711,154625420,154785397,154898561.
2. A method for assessing genomic abnormalities for non-diagnostic purposes, comprising:
selecting a plurality of SNP sites according to claim 1, and constructing a capture probe or a kit capable of capturing nucleotide fragments containing the SNP sites;
extracting DNA of a detection sample;
constructing a detection sample DNA library;
hybridizing the capture probe or the capture probe in the kit with the DNA library for capture and sequencing;
performing bioinformatics analysis on the sequencing result to obtain the sequencing fragment ratio corresponding to each heterozygous SNP locus;
calculating a genome abnormal index based on the sequencing fragment ratio corresponding to the heterozygous SNP locus;
and quantitatively evaluating the genome abnormality according to the genome abnormality index.
3. The method for assessing genomic abnormalities for non-diagnostic purposes as set forth in claim 2, wherein said obtaining the respective ratios of sequenced fragments for each heterozygous SNP site comprises:
acquiring the number of each allele of the heterozygous SNP locus and the total number of all alleles;
the ratio of each allele is calculated using the number of each allele and the total number of all alleles.
4. A capture probe for assessing genomic abnormalities for capturing a nucleotide fragment comprising a plurality of SNP sites of claim 1.
5. A kit for assessing genomic abnormalities, which comprises at least one dose of the probe of claim 4.
6. Use of the probe of claim 4 or the kit of claim 5 in the manufacture of a product for assessing genomic abnormalities.
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