CN114948726A

CN114948726A - Liquid preparation multiple administration system

Info

Publication number: CN114948726A
Application number: CN202210902042.9A
Authority: CN
Inventors: 王众勤; 李守峰; 李博莉; 柏威龙
Original assignee: Shanghai Aucta Pharmaceuticals Co Ltd
Current assignee: Shanghai Aokeyuan Pharmaceutical Co ltd
Priority date: 2022-07-29
Filing date: 2022-07-29
Publication date: 2022-08-30
Anticipated expiration: 2042-07-29
Also published as: CN114948726B

Abstract

The invention provides a liquid preparation multi-administration system, which comprises a syringe, an adapter and a medicament bottle, wherein the adapter is connected with the medicament bottle, and the syringe enters and exits the medicament bottle through the adapter; the adapter comprises an adapter body, a plurality of elastic connectors and a first channel; the elastic connectors are vertically arranged on the adapter body at intervals and at least partially protrude out of the outer wall of the adapter body; the first channel penetrates through the middle of the adapter body. The invention designs the adapter with higher adaptability for the medicament bottle, can be adapted to bottle mouths with different sizes, can avoid the spilling of medicament liquid in the suction process, can also avoid the medicament being stained in the time interval of multiple times of administration, delays deterioration and reduces waste.

Description

Liquid preparation multiple administration system

Technical Field

The invention relates to the technical field of medical appliances, in particular to a liquid preparation multi-administration system.

Background

Liquid administration is a conventional treatment mode, and multiple administration requirements exist in the practical situation, for example, various medicines are firstly proportioned in a medicine bottle according to a certain rule and then are sent to the oral cavity or the affected part of a patient after being sucked by a syringe. However, in the prior art, a multiple-administration system generally only involves an injector and a medicament bottle, which are independent from each other and lack of reasonable and effective adaptation, so that hidden troubles of multiple links such as medicament suction, sealing and the like exist in the multiple-administration process, and the use requirement cannot be met.

Disclosure of Invention

In order to solve at least the technical problems of the background art described above, the present invention provides a liquid preparation multiple administration system.

The liquid preparation multi-administration system comprises a syringe, an adapter and a medicament bottle, wherein the adapter is connected with the medicament bottle, and the syringe enters and exits the medicament bottle through the adapter;

the adapter comprises an adapter body, a plurality of elastic connectors and a first channel; the elastic connectors are vertically arranged on the adapter body at intervals and at least partially protrude out of the outer wall of the adapter body; the first channel penetrates through the middle of the adapter body.

Furthermore, the adapter also comprises a first adjusting part, a plurality of second channels and a third channel, wherein the third channel is positioned at the outer side of the first channel;

the main body of the elastic connector is arranged in the second channel, one end of the elastic connector protrudes out of the outer wall of the adapter body, and the other end of the elastic connector protrudes into the third channel; the first adjusting portion is located in the third channel and is adapted to adjust the degree to which the elastic coupling protrudes into the third channel.

Further, the first adjusting part comprises a first sub-adjusting part, a second sub-adjusting part and a guiding part;

one ends, far away from each other, of the first sub-adjusting part and the second sub-adjusting part are respectively fixed on the top wall and the bottom wall of the third channel, and one sides, facing the elastic combining piece, of the first sub-adjusting part and the second sub-adjusting part are respectively provided with a plurality of first convex parts; the guide part is fixedly arranged in the third channel and is positioned in the middle of the first sub-adjusting part and the second sub-adjusting part; and a second convex part is arranged at one end of the elastic combining piece, which protrudes into the third channel.

Further, the adapter also includes at least one telescoping portion disposed on the adapter body, the telescoping portion being located intermediate the top and bottom walls of the third passageway.

Furthermore, the adapter also comprises a second adjusting part connected with the rotating shaft of the adapter body, the second adjusting part comprises a limiting part and a contact part, and the limiting part and the contact part are fixedly connected or integrally formed;

the limiting part is arranged in a wall groove on the outer wall of the adapter body, and the contact part partially protrudes into the first channel.

Furthermore, the contact part and/or the tube wall of the injector are/is provided with convex grains.

Furthermore, the adapter still includes at least one elasticity sealing, elasticity sealing one end with the inner wall connection of first passageway bottom, the other end is the expansion end.

Furthermore, the elastic sealing part comprises a first end part, a second end part, a third end part and a fourth end part, and the first end part is a movable sealing end;

the second end part and the third end part are connected with the inner wall of the bottom end of the first channel, connecting points are respectively positioned at the lower part and the upper part, and the fourth end part is connected with the bottom wall of the adapter; a first distance from the second end to the first end is less than a second distance from the third end to the first end.

Furthermore, a fourth channel is further arranged on the inner wall of the bottom end of the first channel, the fourth channel comprises a first opening part positioned at the upper part and a second opening part positioned at the lower part, a multi-stage limiting groove is arranged at the first opening part, and the third end part is fixedly arranged at the first opening part; the second end part is fixedly arranged on the inner side wall of the fourth channel close to the first channel; the fourth end part comprises a sliding groove which is in sliding connection with the fixed shaft on the bottom wall of the adapter;

and the second end part and the third end part are respectively fixedly connected with the first end part connecting point through a first elastic rope and a second elastic rope, and the elastic coefficient of the first elastic rope is smaller than that of the second elastic rope.

Further, the adapter also includes a cover portion disposed at a top end of the first channel.

In the scheme of the invention, the administration agent bottle is provided with the adapter with higher adaptability, so that the agent liquid in the suction process can be prevented from spilling, the agent can be prevented from being stained in the time interval of multiple administrations, and the deterioration is delayed.

Drawings

In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings needed to be used in the embodiments will be briefly described below, it should be understood that the following drawings only illustrate some embodiments of the present invention and therefore should not be considered as limiting the scope, and for those skilled in the art, other related drawings can be obtained according to the drawings without inventive efforts.

FIG. 1 is a schematic diagram of the components of a multiple-administration system for liquid preparations according to an embodiment of the present invention.

Fig. 2 is a schematic structural diagram of the adapter (2) related to the first adjusting part (204) disclosed in the embodiment of the invention.

Fig. 3 is a schematic structural diagram of another adapter (2) related to the first adjusting part (204) disclosed in the embodiment of the invention.

Fig. 4 is a schematic structural diagram of another adapter (2) related to the first adjusting part (204) disclosed in the embodiment of the invention.

Fig. 5 is a schematic structural diagram of a compression limit related to the first adjustment part (204) disclosed in the embodiment of the present invention.

Fig. 6 is a schematic structural diagram of the adapter (2) related to the second adjusting part (208) disclosed in the embodiment of the invention.

Fig. 7 is a schematic structural diagram of a modification of the second adjustment part (208) disclosed in the embodiment of the invention.

Fig. 8 is a schematic view of the overall structure of the adapter (2) relating to the elastic sealing part (209) disclosed in the embodiment of the present invention.

Fig. 9 is a partially enlarged schematic structural view of the adapter (2) relating to the elastic sealing part (209) disclosed in the embodiment of the present invention.

Fig. 10 is another enlarged partial structure diagram of the adapter (2) relating to the elastic sealing part (209) disclosed in the embodiment of the invention.

Fig. 11 is a schematic view of the operational state of the structural components of a multiple-administration system for liquid preparations according to an embodiment of the present invention.

Detailed Description

In order to make the objects, technical solutions and advantages of the present invention clearer, the present invention will be described in further detail with reference to the accompanying drawings, and it is apparent that the described embodiments are only a part of the embodiments of the present invention, not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

The terminology used in the embodiments of the present application is for the purpose of describing particular embodiments only and is not intended to be limiting of the application. As used in the examples of this application and the appended claims, the singular forms "a", "an", and "the" are intended to include the plural forms as well, unless the context clearly indicates otherwise, and "a plurality" typically includes at least two.

It should be understood that the term "and/or" as used herein is merely one type of association that describes an associated object, meaning that three relationships may exist, e.g., a and/or B may mean: a exists alone, A and B exist simultaneously, and B exists alone. In addition, the character "/" herein generally indicates that the former and latter related objects are in an "or" relationship.

It should be understood that although the terms first, second, third, etc. may be used to describe … … in the embodiments of the present application, these … … should not be limited to these terms. These terms are used only to distinguish … …. For example, the first … … can also be referred to as the second … …, and similarly the second … … can also be referred to as the first … … without departing from the scope of embodiments herein.

The words "if", as used herein, may be interpreted as "at … …" or "at … …" or "in response to a determination" or "in response to a detection", depending on the context. Similarly, the phrases "if determined" or "if detected (a stated condition or event)" may be interpreted as "when determined" or "in response to a determination" or "when detected (a stated condition or event)" or "in response to a detection (a stated condition or event)", depending on the context.

It is also noted that the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a good or system that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such good or system. Without further limitation, an element defined by the phrase "comprising an … …" does not exclude the presence of other like elements in a commodity or system that includes the element.

Preferred embodiments of the present invention will be described in detail below with reference to the accompanying drawings.

Referring to fig. 1, fig. 1 is a schematic structural diagram of a multiple-administration liquid preparation system according to an embodiment of the present invention. As shown in fig. 1 and 2, a multiple liquid preparation administration system according to an embodiment of the present invention includes a syringe (1), an adapter (2), and a medicine bottle (3), wherein the adapter (2) is connected to the medicine bottle (3), and the syringe (1) enters and exits the medicine bottle (3) through the adapter (2);

wherein, the adapter (2) comprises an adapter body (201), a plurality of elastic connectors (202) and a first channel (203); the elastic connectors (202) are vertically arranged on the adapter body (201) at intervals and at least partially protrude out of the outer wall of the adapter body (201); the first channel (203) penetrates through the middle of the adapter body (201).

In the embodiment of the invention, the syringe and the medicament bottle in the existing multiple administration system are mutually independent and are not designed in a matching way, namely, a single medicament is placed in the medicament bottle or a plurality of medicaments are arranged in the medicament bottle according to a certain rule, and then the syringe is used for extending into the medicament bottle to suck medicament liquid and then sending the medicament liquid into the oral cavity or the diseased part of a patient. Obviously, the medicine bottle in the multiple administration system does not have a plug portion which is flexibly adapted, so that the medicine is easily spilled out in the process of sucking the medicine liquid by the syringe, the multiple administration has a larger time interval, and the shortage of the plug portion with good adaptation performance easily causes the contamination and the deterioration of the medicine.

In view of the above-mentioned drawbacks, the present invention proposes a new liquid formulation multiple administration system, and the key of the system is to provide an adapter (2) with high suitability. Specifically, referring to fig. 1 and 11, when in use, the adapter (2) is firstly installed at the mouth of the medicine bottle (3) already containing medicine liquid, the outer wall of the adapter (2) is protruded with an elastic connector (202), and the elastic connector (202) can be in friction combination with the inner wall of the mouth of the medicine bottle (3), so that the mouth of the medicine bottle is sealed and the medicine liquid is isolated from the outside; then, the injector (1) is inserted into a through first channel (203) arranged in the middle of the adapter (2) to suck the medicament liquid in the medicament bottle (3), the injector (1) is pulled out after a proper amount of medicament liquid is sucked, and the sucked medicament liquid is injected into the oral cavity of a patient; the steps are repeated at other administration occasions to realize multiple administrations. Therefore, the adapter (2) with high adaptability is designed for the medicament bottle, so that the medicament liquid can be prevented from spilling in the suction process, and the medicament can be prevented from being stained and delayed to deteriorate in the time interval of multiple times of administration.

The syringe (1) according to the present invention may be a needle type or a needle-free type, and the present invention is not limited thereto.

Further, before the adapter (2) is attached to the medicine bottle (3), the medicine liquid may be dispensed into the medicine bottle (3), for example.

1) Weighing lamotrigine, a suspending agent, a wetting agent, a sweetening agent, a flavoring agent, a pH regulator, an antioxidant and a preservative according to a material ratio, and placing the materials into a medicament bottle; when in use, a proper amount of water is added and stirred to be dispersed evenly, and the prepared lamotrigine suspension can be taken for 1 to 2 months.

Material(s)	Weighing weight or volume
		Lamotrigine	1000 mg
Sodium carboxymethylcellulose	50 mg
		Polysorbate-80	100 mg
Sucralose	100 mg
		Orange essence	100 mg
Disodium hydrogen phosphate	150 mg
		Citric acid	250 mg
Hydroxy phenylpropyl ester sodium salt	20 mg
		Sodium hydroxybenzene methyl ester	200 mg
Sodium thiosulfate	100 mg
		Water (W)	To 100 mL

2) 25000 mg of vigabatrin, 5000 mg of sucrose, 50 mg of orange essence, 500 mg of sodium methyl p-hydroxybenzoate, 500 mg of tween-8050 mg and 100 mg of procyanidine are accurately weighed into a medicament bottle, when the composition is taken, a proper amount of 0.05M phosphate buffer with pH =6.8 is added into the composition, the composition is completely dissolved to prepare 500 mL of solution, and the prepared vigabatrin solution can be taken for 2 weeks to 1 month.

Material(s)	Weighing of
		Vigabatrin	25000 mg
Sucrose	5000 mg
		Tween-80	50 mg
Sodium methyl p-hydroxybenzoate	500 mg
		Orange essence	50 mg
Procyanidins	100 mg
		0.05M phosphate buffer pH =6.8	To 500 mL

Further, the adapter (2) further comprises a first adjusting part (204), a plurality of second channels (205) and a third channel (206), wherein the third channel (206) is positioned outside the first channel (203);

one end of each second channel (205) is communicated with the third channel (206), and the other end of each second channel is communicated with the outer wall of the adapter body (201); the main body of the elastic connector (202) is arranged in the second channel (205), one end of the elastic connector protrudes out of the outer wall of the adapter body (201), and the other end of the elastic connector protrudes into the third channel (206); the first adjustment portion (204) is located in the third channel (206), the first adjustment portion (204) adapted to adjust the extent to which the elastic coupling (202) protrudes into the third channel (206).

In the embodiment of the invention, because of the difference of the sizes of the medicament bottles, in order to improve the adaptation performance of the adapter (2), the invention is further provided with a first adjusting part (204). Referring to fig. 2, a third channel (206) and a plurality of second channels (205) are further arranged in the adapter (2), the third channel (206) and each second channel (205) are arranged generally vertically, a main body of the elastic connector (202) is located in the second channel (205), and two ends of the elastic connector respectively protrude out of the outer wall of the adapter body (201) and the third channel (206), so that the arrangement of the elastic connector (202) is realized through the structure; meanwhile, a first adjusting part (204) is further arranged in the third channel (206), the degree of the elastic connecting piece (202) protruding into the third channel (206) can be changed by adjusting the form of the first adjusting part (204) (for example, the adapter body (201) is pressed up and down to enable the first adjusting part (204) to deform), and further the length of the elastic connecting piece (202) protruding out of the outer wall of the adapter body (201) is changed. Thus, the adjusted adapter body (201) can be adapted to a medicament vial (3) having a larger vial opening size range.

Further, the first adjusting part (204) comprises a first sub-adjusting part (2041), a second sub-adjusting part (2042) and a guiding part (2043);

wherein, the ends of the first sub-adjusting part (2041) and the second sub-adjusting part (2042) far away from each other are respectively fixed on the top wall and the bottom wall of the third channel (206), and one sides facing the elastic combining part (202) are respectively provided with a plurality of first convex parts (2044); the guide part (2043) is fixedly arranged in the third channel (206) and is positioned between the first sub-adjusting part (2041) and the second sub-adjusting part (2042); one end of the elastic joint part (202) which protrudes into the third channel (206) is provided with a second convex part (2045).

In the embodiment of the invention, referring to fig. 2 and 3, in order to realize the adjustment of the form of the first adjusting part (204), the invention is characterized in that a first sub-adjusting part (2041) and a second sub-adjusting part (2042) are respectively and fixedly arranged on the top wall and the bottom wall of the third channel (206), and the movable ends of the first sub-adjusting part and the second sub-adjusting part are opposite to each other at intervals of a guide part (2043); meanwhile, one side of the first sub-adjusting part (2041) and one side of the second sub-adjusting part (2042) facing the elastic joint part (202) are also provided with a plurality of first convex parts (2044), and correspondingly, one end of the elastic joint part (202) is provided with a second convex part (2045). Therefore, the distances of the movable ends of the first sub-adjusting part (2041) and the second sub-adjusting part (2042) can be changed by vertically compressing the adapter body (201), the movable ends of the first sub-adjusting part (2041) and the second sub-adjusting part (2042) are contacted with the guide surface of the guide part (2043), so that the first sub adjustment part (2041) and the second sub adjustment part (2042) approach the elastic joint part (202), when the first convex part (2044) and the second convex part (2045) are contacted (when the compression is started, the first convex part (2044) and the second convex part (2045) are firstly in initial contact to provide initial thrust, then the first convex part (2044) and the second convex part (2045) are changed into close contact under the action of the guide part (2043), and at the moment, larger thrust can be provided, the elastic connecting part (202) can be pushed out by the first adjusting part (204), and the adjusted adapter (2) can be matched with a medicine bottle with a larger bottle opening size.

It should be noted that, a plurality of first convex portions (2044) may be provided, and the closer to the two walls of the third channel (206), the larger the first convex portion (2044) is, and accordingly, a single sub-adjustment portion may correspond to a plurality of elastic coupling members (202) (fig. 2 and 3 only schematically illustrate two elastic coupling members (202)), so that the first convex portions (2044) provided according to the above size relationship can achieve that the single sub-adjustment portions at different height positions can all be pushed to approximately the same extent. And, as for the style of the second convex portion (2045), it can also be designed to be similar to the first convex portion (2044), so that there is also a benefit that the second convex portion (2045) itself can be weakly fastened with the gap between the adjacent first convex portions (2044) (when the size of the second convex portion (2045) is significantly smaller than that of the first convex portion (2044)), thereby facilitating the limiting effect.

Further, the adaptor (2) further comprises at least one telescopic part (207) arranged on the adaptor body (201), wherein the telescopic part (207) is located in the middle of the top wall and the bottom wall of the third channel (206).

In the embodiment of the present invention, referring to fig. 4, the adapter body (201) is further provided with a telescopic portion (207), and the telescopic portion (207) is arranged to make the compression of the adapter (2) easier, so that the movable ends of the first sub-adjusting portion (2041) and the second sub-adjusting portion (2042) can have more moving ranges, so as to drive the first convex portion (2044) to apply a larger force to the second convex portion (2045), or drive the larger first convex portion (2044) to apply a force, and finally can transmit more force to the second convex portion (2044), so as to adjust the protruding length of the elastic coupling member (202).

The telescopic part (207) may adopt a design scheme in the prior art (a telescopic design scheme of a telescopic bellows may be adopted), and a design scheme with multi-stage telescopic and restoring functions is preferably adopted. Wherein the different degrees of expansion and contraction correspond to different protruding lengths of the elastic coupling member (202), and the existence of the function of expansion and contraction restoration facilitates the repeated adaptation of the adapter to the medicament bottle of the original bottle mouth size. In addition, the first adjusting part (204) and the telescopic part (207) can be arranged in a matched mode in a group mode, accordingly, the adjustment can be carried out respectively, and therefore the medicine bottle (3) with the longer bottle mouth can be adapted conveniently.

In addition, in addition to the telescopic bellows solution, the telescopic positioning structure of the adapter (2) may also be configured as shown in fig. 5, in which the telescopic portion (207) is retained, but is disposed at a horizontal position corresponding to the first adjusting portion (204), and meanwhile, the second convex portion (2045) is provided with a limiting groove, and the limiting groove and the first convex portion (2044) can realize the position clamping, so that it is not necessary to separately arrange a limiting component on the re-telescopic portion (207), and the complexity and implementation cost of the adapter (2) can be reduced. In order to ensure the pushing-out degree of the second convex portion (2045) to the elastic connector (202), the shape of the second convex portion (2045) may be subjected to special-shaped design (for example, multi-level protrusions) to simultaneously realize pushing-out and clamping, and the invention is not repeated in the case of the special-shaped shape.

The two telescopic parts (207) may form a group, and are respectively located at the spatial positions of the upper side and the lower side of the guide part (2043) and the first sub-adjusting part (2041) and the second sub-adjusting part (2042), so that the arrangement does not affect the normal guiding function of the guide part (2043). In addition, the guide part (2043) is not separately arranged, when the adapter body (201) is compressed, the part, close to the inner side wall, of the telescopic part (207) in the third channel (206) forms a protrusion after contraction, the first sub adjusting part (2041) and the second sub adjusting part (2042) can be guided, and the guide part can be equivalently regarded as the guide part (2043).

Further, the adapter (2) further comprises a second adjusting portion (208) connected with the rotating shaft of the adapter body (201), the second adjusting portion (208) comprises a limiting portion (2081) and a contact portion (2082), and the limiting portion (2081) and the contact portion (2082) are fixedly connected or integrally formed;

the limiting part (2081) is arranged in a wall groove on the outer wall of the adapter body (201), and the contact part (2082) partially protrudes into the first channel (203).

In the embodiment of the invention, the adapter (2) of the invention is further provided with a second adjusting part (208), as shown in fig. 6 and 11, a limiting part (2081) at the outer part is positioned in the wall groove of the outer wall, and a contact part (2082) at the inner part partially protrudes into the first channel (203). Therefore, after the adapter (2) is inserted into the mouth of the medicine bottle (3) and stable clamping is achieved by adjusting the first adjusting part (204), the syringe (1) is inserted into the first channel (203), the syringe (1) can exert extrusion force on the contact part (2082) when being inserted to the position, the limiting part (2081) can protrude out of the wall groove due to the fact that the second adjusting part (208) is connected with the rotating shaft of the adapter body (201), the limiting part (2081) can be in contact with the inner wall of the bottleneck of the medicine bottle (3) at the moment, clamping is achieved, and when the syringe (1) is pulled out of the first channel (203) after sucking a sufficient amount of medicine, the adapter (2) in a clamping state cannot be separated from the mouth of the medicine bottle (3) easily due to friction force generated during pulling out.

In order to prevent the medicine liquid from flowing out of the bottle through the wall groove and the first channel (203), the inner wall thickness of the position corresponding to the first channel (203) is set to be thin, or a hole is formed in the position corresponding to the inner wall of the first channel (203), and a thin soft film (not shown in the figure) is arranged at the hole to form the interlayer. At this time, the contact part (2082) does not directly protrude into the first passage (203), and can still be in contact with the injector (1), and the force applied to the contact part (2082) by the injector (1) is not affected basically because the contact partition layer is thin. In addition, the rotating shaft of the second adjusting part (208) is preferably arranged on the contact part (2082), and a return spring (not shown in the figure) is preferably arranged on the rotating shaft, so that the second adjusting part (208) is returned into the wall groove under the condition of not being pressed by the syringe (1), and the adapter (2) is conveniently taken down.

In addition, when the first adjusting part (204) and the telescopic part (207) are arranged in a matched mode in a plurality of groups, the second adjusting part (208) is arranged at the bottommost end/secondary bottom end position of the adapter (2) preferentially, so that the limiting part (2081) is located at the bottleneck of the medicine bottle (3) when extending and unfolding.

In addition, the invention further improves the condition that the outer wall of the injector (1) is interfered with the contact part (2082) of the second adjusting part (208) when the injector is pulled out, so that the injector is difficult to pull out. Referring to fig. 7, a rotating wheel (2083) may be disposed at an end of the contact portion (2082), and when the injector (1) is pulled out, the rotating wheel (2083) is rotatably connected to an outer wall of the injector (1), and at this time, the contact between the contact portion (2082) and the outer wall of the injector (1) does not cause significant interference, and the pulling out of the injector (1) is not affected.

Further, the contact part (2082) and/or the tube wall of the injector (1) are provided with convex grains.

In the embodiment of the invention, in order to enhance the transmission of the driving force of the injector (1) to the second adjusting part (208), convex grains can be further arranged on the contact surface of the contact part (2082) and the pipe wall of the injector (1), so that more force is transmitted to the limiting part (2081) in the process of inserting the injector (1) into the first channel (203). It is especially preferable that the contact part (2082) and the wall of the syringe (1) are provided with convex lines, but the convex lines should preferably be provided in a form that does not hinder the extraction of the syringe (1), for example, in a one-way convex line design.

Furthermore, adapter (2) still includes at least one elasticity sealing (209), elasticity sealing (209) one end with the inner wall connection of first passageway (203) bottom, the other end is the expansion end.

In the embodiment of the invention, referring to fig. 8, the bottom end of the first channel (203) is further provided with an elastic sealing part (209) which is normally in a closed state, the elastic sealing part (209) can be pushed open when the syringe (1) is inserted so as to enter the medicament bottle (3) to suck the medicament liquid, and when the syringe (1) is pulled out, the elastic sealing part (209) can be automatically reset so as to re-seal the bottom end of the first channel (203), so that the medicament liquid can be prevented from flowing out of the medicament bottle (3).

The elastic sealing portion (209) may be configured to seal the first channel (203) in a sheet shape, a spherical shape, or the like, but the invention is not limited thereto.

Further, the elastic sealing part (209) comprises a first end part (2091), a second end part (2092), a third end part (2093) and a fourth end part (2094), wherein the first end part (2091) is a movable blocking end;

wherein the second end portion (2092) and the third end portion (2093) are connected to the inner wall of the bottom end of the first channel (203) at connection points located at the lower part and the upper part, respectively, and the fourth end portion (2094) is connected to the bottom wall of the adapter (2); a first distance of the second end (2092) to the first end (2091) is less than a second distance of the third end (2093) to the first end (2091).

In the embodiment of the invention, as shown in fig. 9, the connection mode of the elastic sealing part (209) and the inner wall of the bottom end of the first channel (203) is designed specifically, two second end parts (2092) and three third end parts (2093) which are positioned at different heights are arranged, the two end parts can reset the elastic sealing part (209) at different opening degrees, and meanwhile, the fourth end part (2094) is additionally arranged, so that a lever structure is formed, the first end part (2091) can be in a normally closed state, and can be opened when the injector (1) is inserted.

Further, a fourth channel (2095) is further arranged on the inner wall of the bottom end of the first channel (203), the fourth channel (2095) comprises a first opening portion (20951) located at the upper portion and a second opening portion (20952) located at the lower portion, a multi-stage limiting groove is arranged at the first opening portion (20951), and the third end portion (2093) is fixedly arranged at the first opening portion (20952); the second end part (2092) is fixedly arranged on the inner side wall of the fourth channel (2095) close to the first channel (203); the fourth end part (2094) comprises a sliding groove (20941), and the sliding groove (20941) is in sliding connection with a fixed shaft on the bottom wall of the adapter (2);

and the second end part (2092) and the third end part (2093) are fixedly connected with the connection point of the first end part (2091) through a first elastic rope (2096) and a second elastic rope (2097), and the elastic coefficient of the first elastic rope (2096) is smaller than that of the second elastic rope (2097).

In the embodiment of the invention, as shown in fig. 9 and 10, the fixing mode of the elastic sealing part (209) is further improved, a fourth channel (2094) with openings at the upper end and the lower end is arranged on the inner wall of the bottom end of the first channel (203), and a multi-stage limiting groove is also arranged in the first opening part (20951) with the opening at the upper end, so that the third end (2093) can be limited and fixed in a grading way; and the second end part (2092) is fixedly arranged in the fourth channel (2095), and at the moment, the second end part (2092), the third end part (2093) and the fourth end part (2094) also form the lever structure, so that the first end part (2091) is in a normally closed state and can be opened when the injector (1) is inserted. In addition, the elastic coefficient of the first elastic rope (2096) is smaller than that of the second elastic rope (2097), namely the upper limit of the tensile force which can be provided by the second end part (2092) is smaller than that of the third end part (2093), so that the tensile force is applied to the first end part (2091) in a grading and continuous mode.

The working principle and the benefit of the elastic sealing part (209) are analyzed as follows:

1) the injector (1) is inserted into the first channel (203), the lower end part of the injector (1) is firstly contacted with the third end part (2093) and applies force to the third end part to enable the third end part to enter a lower limiting groove (shown in a figure 11), at the moment, the second elastic rope (2097) is in a critical tensioning state or below, the first end part (2091) is provided with normally closed tension by the first elastic rope (2096), the elasticity coefficient of the first elastic rope (2096) is small, so that the elastic sealing part (209) is pushed to be opened by the injector (1) more easily, and the injector (1) can smoothly enter the bottle body of the medicine bottle (3) to suck the medicine.

The diameters of the syringes (1) inserted into the first channel (203) are different, the syringe (1) with the larger diameter can generate strong acting force on the third end part (2093), the syringe (1) with the smaller diameter can generate weak acting force on the third end part (2093), the tensile force borne by the elastic sealing part (209) can exceed the conventional deformation range of the first elastic rope (2096) and be excessively elongated, and the second elastic rope (2097) starts to continuously bear force at the moment, so that the first elastic rope (2096) can be prevented from being broken or deformed, damaged or even broken.

In addition, the fourth end part (2094) is also provided with a sliding groove (20941), the sliding groove (20941) can slide relative to the fixed shaft on the bottom wall of the adapter (2) in the opening process of the first end part (2091), and then the distance between the fixed shaft and the elastic rope connecting point of the first end part (2091) is adjusted, so that the moment is adjusted. Thereby being more beneficial to opening the elastic sealing part (209), protecting the elastic rope to a certain degree and avoiding the breakage of the elastic rope due to excessive stress.

2) The syringe (1) is pulled out after sucking enough medicine, and at the moment, the adapter (2) is still stable on the medicine bottle (3) due to the limiting effect of the second adjusting part (208).

The syringe (1) is separated from the first end part (2091) firstly, the first elastic rope (2096) pulls the first end part (2091) to reset, and at the moment, the second elastic rope (2097) is not pulled any more and is in a critical tensioning state or below, so that the third end part (2093) is in an easily stressed movable state; meanwhile, the third end part (2093) can enter a limit groove at a higher position again due to the contact friction force of the syringe (1) and the third end part (2093), at the moment, the second elastic rope (2097) is continuously pulled and is in a critical tensioning state, the first end part (2091) is further pulled, the bottom opening of the first channel (203) is blocked by the first end part (2091) in an enhanced mode, and the medicine liquid in the medicine bottle (3) is prevented from flowing out.

It should be noted that the third end portion (2093) may also be provided with protruding grains, so that the protruding grains can be matched with the protruding grains arranged on the outer wall of the injector (1), and the position switching of the third end portion (2093) in each level of limiting groove is facilitated; and, the multistage spacing groove sets up to more than 2 grades, can set up freely specifically, this invention is not repeated here.

Further, the adaptor (2) further comprises a cover portion, and the cover portion is arranged at the top end of the first channel (203).

In the embodiment of the invention, a cover part (not shown in the figure) is further arranged at the position of the first channel (203) at the top end of the adapter (2), and under the condition that the syringe (1) is not inserted into the first channel (203), the cover part can be used for plugging the first channel (203) to prevent external dust and the like from entering the medicine bottle (3), and can also be matched with the elastic sealing part (209) to prevent medicine liquid in the medicine bottle (3) from easily flowing out. Since the structural design of the cover part is quite conventional, the present invention will not be described herein in detail, but it can be selected from at least various forms of independent cover, split hinged cover, integral hinged cover, and the like.

It should be noted that the foregoing is only illustrative of the preferred embodiments of the present invention and the technical principles employed. It will be understood by those skilled in the art that the present invention is not limited to the particular embodiments described herein, but is capable of various obvious changes, rearrangements and substitutions as will now become apparent to those skilled in the art without departing from the scope of the invention. Therefore, although the present invention has been described in more detail by the above embodiments, the present invention is not limited to the above embodiments, and may include other equivalent embodiments without departing from the spirit of the present invention.

Claims

1. A liquid formulation multiple delivery system characterized by: the injection device comprises an injector (1), an adapter (2) and a medicament bottle (3), wherein the adapter (2) is connected with the medicament bottle (3), and the injector (1) enters and exits the medicament bottle (3) through the adapter (2);

2. A liquid formulation multiple delivery system according to claim 1, wherein: the adapter (2) further comprises a first adjusting part (204), a plurality of second channels (205), and a third channel (206), wherein the third channel (206) is positioned outside the first channel (203);

one end of each second channel (205) is communicated with the third channel (206), and the other end of each second channel is communicated with the outer wall of the adapter body (201), the main body of the elastic connector (202) is arranged in the second channel (205), one end of the elastic connector protrudes out of the outer wall of the adapter body (201), and the other end of the elastic connector protrudes into the third channel (206); the first adjustment portion (204) is located in the third channel (206), the first adjustment portion (204) being adapted to adjust the extent to which the resilient coupling (202) protrudes into the third channel (206).

3. A liquid formulation multiple delivery system according to claim 2, wherein: the first adjusting part (204) comprises a first sub adjusting part (2041), a second sub adjusting part (2042) and a guide part (2043);

wherein, the ends of the first sub-adjusting part (2041) and the second sub-adjusting part (2042) far away from each other are respectively fixed on the top wall and the bottom wall of the third channel (206), and one sides facing the elastic joint part (202) are respectively provided with a plurality of first convex parts (2044); the guide part (2043) is fixedly arranged in the third channel (206) and is positioned between the first sub-adjusting part (2041) and the second sub-adjusting part (2042); one end of the elastic joint part (202) which protrudes into the third channel (206) is provided with a second convex part (2045).

4. A liquid formulation multiple delivery system according to claim 3, wherein: the adapter (2) further comprises at least one telescoping portion (207) disposed on the adapter body (201), the telescoping portion (207) being located intermediate the top and bottom walls of the third channel (206).

5. A liquid formulation multiple delivery system according to any one of claims 1 to 4, wherein: the adapter (2) further comprises a second adjusting portion (208) connected with the rotating shaft of the adapter body (201), the second adjusting portion (208) comprises a limiting portion (2081) and a contact portion (2082), and the limiting portion (2081) and the contact portion (2082) are fixedly connected or integrally formed;

6. A liquid formulation multiple delivery system according to claim 5, wherein: the contact part (2082) and/or the pipe wall of the injector (1) are/is provided with convex lines.

7. A liquid formulation multiple delivery system according to claim 1 or 6, wherein: adapter (2) still includes at least one elasticity sealing (209), elasticity sealing (209) one end with the inner wall connection of first passageway (203) bottom, the other end is the expansion end.

8. A liquid formulation multiple delivery system according to claim 7, wherein: the elastic sealing part (209) comprises a first end part (2091), a second end part (2092), a third end part (2093) and a fourth end part (2094), and the first end part (2091) is a movable blocking end;

9. A liquid formulation multiple delivery system according to claim 8, wherein: a fourth channel (2095) is further arranged on the inner wall of the bottom end of the first channel (203), the fourth channel (2095) comprises a first opening portion (20951) located at the upper portion and a second opening portion (20952) located at the lower portion, a multi-stage limiting groove is arranged at the first opening portion (20951), and the third end portion (2093) is fixedly arranged at the first opening portion (20951); the second end part (2092) is fixedly arranged on the inner side wall of the fourth channel (2095) close to the first channel (203); the fourth end part (2094) comprises a sliding groove (20941), and the sliding groove (20941) is in sliding connection with a fixed shaft on the bottom wall of the adapter (2);

10. A liquid formulation multiple delivery system according to any one of claims 1 to 4, 6 to 9, wherein: the adapter (2) further comprises a cover portion arranged at the top end of the first channel (203).