CN114948422A

CN114948422A - Eye tissue processing apparatus, eye tissue processing control method, and readable medium

Info

Publication number: CN114948422A
Application number: CN202110419341.2A
Authority: CN
Inventors: 黄承好
Original assignee: Fulakai Consulting Shanghai Co ltd
Current assignee: Fulakai Consulting Shanghai Co ltd
Priority date: 2021-02-24
Filing date: 2021-04-19
Publication date: 2022-08-30
Also published as: TWI770835B; TW202233141A

Abstract

The invention belongs to the technical field of medical equipment, and discloses eye tissue processing equipment, an eye tissue processing control method and a readable medium. The eye tissue treatment apparatus includes a controller connected with a laser light source, an optical system, and an optical scanning movement device, and configured to control the laser light source to generate a femtosecond laser beam; controlling the optical system to direct the femtosecond laser beam to the optical scanning movement device; controlling the optical scanning movement device to generate a target treatment region in the eye tissue by the femtosecond laser beam, the target treatment region comprising an upper section, a lower section and a through section, the through section penetrating the target treatment region from the upper section to the lower section, and controlling the optical scanning movement device to make a removal incision in the eye tissue by the femtosecond laser beam, the removal incision connecting from an outer surface of the eye tissue to the target treatment region and penetrating through the section. The eye tissue treatment device has enough strength of the target treatment area to be removed and can be taken out by a complete clamp.

Description

Eye tissue processing apparatus, eye tissue processing control method, and readable medium

Technical Field

The present invention relates to the technical field of medical devices, and in particular, to an eye tissue treatment device, an eye tissue treatment control method, and a readable medium.

Background

For the purpose of correcting Vision, the prior art uses an excimer Laser to change the curvature of the cornea of the eye, which may be referred to as Laser Vision Correction (LVC). Among the laser vision correction procedures, the most common is excimer laser in situ lamellar keratoplasty (LASIK), which accounts for approximately 85% of all laser vision correction procedures.

In the early days of LASIK surgery, the surgeon typically used a physical blade (also known as a microkeratome) to cut a flap of cornea, then opened the flap, and then laser ablated the exposed corneal tissue to change the curvature of the cornea. In recent years, for cutting a corneal flap on the cornea, a method has been developed which uses a femtosecond laser, i.e., a laser pulse light of thousands of laser pulses generates a photocleavage effect to form a very minute point-like cavity to cause tissue separation, thereby forming a corneal flap. The femtosecond laser approach has been used more extensively in LASIK surgery due to its higher safety, repeatability, predictability, and flexibility than microkeratomes. In addition, the femtosecond laser method can reduce the occurrence probability of adverse complications such as iatrogenic keratoconus (steep cornea), corneal flap shift (flat cornea) and irregular corneal flap associated with a microkeratome.

However, in LASIK surgery, since the incision of the flap is large, the flap is difficult to re-support the cornea and resist the strength of the intraocular pressure after surgery, resulting in a severe weakening of the strength of the cornea after surgery.

In addition to LASIK surgery, another laser vision correction method by a femtosecond laser has been developed in recent years, which generates a corneal lens in corneal tissue by the femtosecond laser, and removes or takes out the corneal lens from the corneal tissue via a minimally invasive incision generated by the femtosecond laser to change the curvature of the cornea. In this way, the problem of flap displacement after surgery can be avoided without unduly weakening the cornea, since it is not necessary to produce a flap with a large incision.

As for the method of removing or taking out the corneal lens, there is a method of cutting out two sections in the whole corneal tissue by using a femtosecond laser to form the corneal lens, wherein the two sections include an upper section, which may also be referred to as Cap, which follows the external shape of the cornea, and a lower section, which may also be referred to as Curvature, which has a higher Curvature than the upper section. Next, a second incision is made at the outer periphery of the corneal lens section using a femtosecond laser, and a minimally invasive incision is made through the corneal surface, through which the corneal lens is removed from the corneal tissue. After removal of the corneal lens, the outer curvature of the cornea changes by the diopter necessary to correct the ametropia of the eye (correct vision).

As shown in fig. 1 to 2, U.S. patent No. 10682256 discloses a method for removing a corneal lens, in which in order to prevent the corneal lens from being broken during its removal from corneal tissue (particularly, the peripheral portion of the corneal lens), a compensation thickness DH must be provided between the superior and inferior incised surfaces of the corneal lens to increase the strength of the peripheral portion of the corneal lens. However, by providing the compensation thickness DH between the upper and lower incised planes, the thickness of the corneal lens removed (extracted) is increased, so that the total thickness of the remaining cornea becomes thinner after the operation, which is not favorable for the strength of the cornea against the intraocular pressure.

In addition, when the corneal lens is removed, due to abundant tissue fluid, the upper section and the lower section of the corneal lens are still adhered to the corneal tissue, and a doctor needs to separate the corneal lens from the corneal tissue by using a separation tool and then clamp the corneal lens out by using a clamp; however, for a less experienced physician, it is sometimes not easy to separate the corneal lens from the corneal tissue, which results in the need to repeat the above-mentioned operations, and during the repeated separation and clamping, the corneal lens may be broken, the edge of the corneal lens may be broken incompletely, and a part of the corneal lens still remains in the corneal tissue.

Disclosure of Invention

An object of the present invention is to provide an ocular tissue treatment apparatus, an ocular tissue treatment control method, and a readable medium, which have sufficient strength of a target treatment region to be removed and which can be completely grasped when ocular tissue such as a cornea is removed.

In order to achieve the purpose, the invention adopts the following technical scheme:

an eye tissue treatment apparatus comprising:

a laser light source configured to generate a femtosecond laser beam;

an optical system configured to guide the femtosecond laser beam generated by the laser light source;

an optical scanning movement device configured to apply the femtosecond laser beam from the optical system to an eye tissue through a condenser lens;

a controller connected with the laser light source, the optical system, and the optical scanning movement device, and configured to:

controlling the laser light source to generate the femtosecond laser beam;

controlling the optical system to direct the femtosecond laser beam to the optical scanning movement device;

controlling the optical scanning movement device to generate a target treatment region in the eye tissue by the femtosecond laser beam, wherein the target treatment region comprises an upper section, a lower section and a through section, the through section penetrates the target treatment region from the upper section to the lower section, and controlling the optical scanning movement device to make a removal incision in the eye tissue by the femtosecond laser beam, the removal incision being connected to the target treatment region from an outer surface of the eye tissue and communicating with the through section.

Preferably, the ocular tissue treatment apparatus further comprises:

a removal device configured to remove the target treatment area from the ocular tissue.

Preferably, the controller controlling the optical scanning movement device to generate the target treatment region in the eye tissue by the femtosecond laser beam includes:

generating the lower section;

generating the through section intersecting the undercut plane; and

producing the upper tangent plane connected with the lower tangent plane.

Preferably, the target treatment region further includes a portion to be removed and a sharp edge portion adjacent to the portion to be removed, and the controller controls the optical scanning movement device to ablate the sharp edge portion by the femtosecond laser beam such that the removal device is configured to remove the portion to be removed of the target treatment region from the eye tissue.

generating the undercut surface and ablating the sharp edge portion by the femtosecond laser beam;

generating the through section intersecting the undercut plane; and

producing the upper tangent plane connected with the lower tangent plane.

Preferably, the upper section and the lower section are connected with each other at the outer periphery of the lower section; wherein the content of the first and second substances is controlled,

the sharp edge portion includes a place where the upper cut surface and the lower cut surface are connected to each other at the outer periphery so that the portion to be removed is located at a middle portion of the target processing region.

Preferably, the upper tangential plane and the lower tangential plane are respectively connected with each other at the outer periphery and the central part of the lower tangential plane;

wherein said sharp edge portion comprises the interconnection of said upper and lower cut surfaces at said outer periphery and the interconnection of said upper and lower cut surfaces at said central portion;

wherein the controller controls the optical scanning moving device to ablate and form a cutting plane in the target processing area by the femtosecond laser beam, one end of the cutting plane is connected to the outer peripheries of the upper cutting plane and the lower cutting plane, and the other end is connected to the central parts of the upper cutting plane and the lower cutting plane, so that the cutting plane penetrates through the target processing area from the upper cutting plane to the lower cutting plane.

Preferably, the cut surface has a planar structure, and the cut surface penetrating the target processing region includes: the cutting surface simultaneously cuts the upper section and the lower section;

the removal cut is located on one side of a central axis of the target processing region, and the cut surface is located on one side of the central axis of the target processing region facing away from the removal cut.

Preferably, the sharp edge portion includes a thickness tapered portion, and a minimum value of a tapered thickness of the thickness tapered portion is zero.

Preferably, a radius is provided between a central axis and an outer peripheral edge of the target processing region, the penetration section is a radial section, and the radial section extends in a radial direction from the outer peripheral edge of the target processing region toward the central axis of the target processing region by a width that is one third of the radius.

Preferably, the ocular tissue is a cornea or a crystalline lens.

To achieve the above object, the present invention also provides an eye tissue processing control method for controlling an eye tissue processing apparatus to cause the eye tissue processing apparatus to execute the steps of:

generating a femtosecond laser beam from a laser light source and directing the femtosecond laser beam toward an eye tissue;

generating a target treatment region in an eye tissue by using the femtosecond laser beam, wherein the target treatment region comprises an upper section, a lower section and a through section, and the through section penetrates through the target treatment region from the upper section to the lower section;

making a removal cut in the ocular tissue with the femtosecond laser beam, the removal cut connecting from an outer surface of the ocular tissue to the target treatment region and communicating with the through-cut plane; and

removing the target treatment region within the ocular tissue through the removal incision

Preferably, generating the target treatment region in the ocular tissue by the femtosecond laser beam comprises:

generating the lower section;

generating the through section intersecting the undercut plane; and

producing the upper tangent plane connected with the lower tangent plane.

Preferably, the target treatment region includes a portion to be removed and a sharp edge portion adjacent to the portion to be removed;

in the generation of the target processing region, the sharp edge portion is ablated by the femtosecond laser beam, and the portion to be removed of the target processing region is removed through the removal incision.

generating the through section intersecting the undercut plane; and

producing the upper tangent plane connected with the lower tangent plane.

Preferably, the upper section and the lower section are interconnected at the outer periphery of the target processing area;

Preferably, the upper cut plane and the lower cut plane are respectively connected with each other at the outer periphery and the central part of the target processing area;

wherein a cut surface is ablated in the target processing region by the femtosecond laser beam, one end of the cut surface is connected to the outer peripheral edge, the other end of the cut surface is connected to the central portion, and the cut surface penetrates the target processing region from the upper cut surface to the lower cut surface.

Preferably, the cutting surface has a planar structure, and the cutting surface simultaneously cuts the upper cutting surface and the lower cutting surface;

Preferably, the sharp edge portion includes a tapered thickness portion having a tapered thickness of a minimum value of zero.

Preferably, a radius is provided between a central axis and an outer peripheral edge of the target processing region, the through-cut surface is a radial-cut surface, and the radial-cut surface extends in a radial direction from the outer peripheral edge of the target processing region toward the central axis of the target processing region by a width that is one third of the radius.

Preferably, the ocular tissue is a cornea or a crystal.

To achieve the above object, the present invention further provides a readable medium for storing a computer program for executing the method for controlling the eye tissue treatment.

The invention has the beneficial effects that:

according to the eye tissue processing equipment provided by the invention, after the controller controls the optical scanning moving device to generate the target processing area from the eye tissue by the femtosecond laser beam, a doctor can firstly use the separation tool to stretch into the eye tissue from the through section and then use the flat separation sheet of the separation tool to separate the target processing area from the eye tissue from the upper section and the lower section in advance, so that the clamp for removing can really clamp the target processing area to take out the target processing area, and the problem that the target processing area is pulled and broken in the clamping process of the clamp because the target processing area is attached to the eye tissue can be effectively avoided.

After the femtosecond laser beam is used for generating the target processing area in the eye tissue, a doctor can firstly use the separation tool to stretch into the eye tissue from the through section and then use the flat separation sheet of the separation tool to separate the target processing area from the eye tissue from the upper section and the lower section in advance, so that the removal clamp can clamp the target processing area and take the target processing area out, and the problem that the target processing area is pulled and broken in the clamping process of the clamp because the target processing area is attached to the eye tissue can be effectively avoided.

The readable medium provided by the invention can also achieve the beneficial effects which can be achieved by the eye tissue processing control method.

Further, the present invention provides an eye tissue processing apparatus, wherein the controller controls the optical scanning moving device to ablate the sharp edge portion of the target processing region by the femtosecond laser beam, so that only the portion of the target processing region to be removed is left to be removed from the eye tissue, and the portion to be removed is not broken during the removal process from the eye tissue, thereby avoiding the problem of the prior art that the removed (extracted) portion of the eye tissue is broken, and therefore, the problem of the subsequent removal of the removed (extracted) portion of the eye tissue is not required to set an additional compensation thickness for the target processing region by controlling the optical scanning moving device. According to the actual requirement of the eye tissue treatment, the optical scanning moving device is controlled to make the generated target treatment area have a corresponding thickness, i.e. no additional supplementary thickness is required, i.e. the additional increase of the thickness of the target treatment area required for treating (e.g. correcting) the eye tissue can be avoided, thereby achieving the purpose of maintaining the strength of the eye tissue to the maximum extent.

Similarly, the method for controlling treatment of eye tissue and the readable medium provided by the present invention can also achieve the beneficial effects achieved by the aforementioned apparatus for treating eye tissue.

Drawings

FIG. 1 is a schematic cross-sectional view of one form of a prior art method of producing a corneal lens in a cornea;

FIG. 2 is a schematic cross-sectional view of another form of a prior art method of producing a corneal lens in a cornea;

FIG. 3a is a schematic view of an ocular tissue treatment device of the present invention creating a pattern of target treatment zones in ocular tissue;

FIG. 3b is a cross-sectional view of FIG. 3a at A-A;

FIG. 4 is a schematic view of an ocular tissue treatment apparatus of the present invention in a state of creating a transection in ocular tissue;

FIG. 5a is a schematic view of the eye tissue treatment apparatus of the present invention in a state where sharp edge portions are generated in the eye tissue;

FIG. 5b is a schematic view of the ocular tissue treatment device of the present invention in a state of creating a transection in ocular tissue;

FIG. 5c is a schematic view of the eye tissue treatment apparatus of the present invention in a state of generating an upper section of eye tissue;

FIG. 5d is a schematic view of the ocular tissue treatment apparatus of the present invention in a state in which it has created a removal incision in ocular tissue;

FIG. 6a is a schematic view of the eye tissue treatment apparatus of the present invention in a state where the separation tool is not used on the eye tissue;

FIG. 6b is a schematic view of the eye tissue treatment apparatus of the present invention in a state where the separating tool is extended from the through-cut plane into the upper and lower cut planes of the target treatment region;

FIG. 6c is a schematic view of the ocular tissue treatment device of the present invention in a state in which the target treatment region is separated from the ocular tissue by a viewing angle using the separation tool;

FIG. 6d is a schematic view of the ocular tissue treatment device of the present invention in a state of separating the target treatment region from the ocular tissue at another angle of view using the separating tool;

FIG. 7a is a schematic view of an ocular tissue treatment device of the present invention creating another form of target treatment area in ocular tissue;

FIG. 7B is a cross-sectional view of FIG. 7a at B-B;

fig. 8 is a schematic structural view of the ocular tissue treatment apparatus of the present invention.

In the figure:

1. cutting into a lower section; 11. an outer peripheral edge;

2. cutting into upper sections; 21. an outer peripheral edge;

3. penetrating the section;

4. removing the incision;

5. a separation device; 51. a handle; 52. a short separator sheet; 53. a long separator sheet;

8. cutting off the section;

100. a device for treating ocular tissue; 101. a laser light source; 102. an optical system; 103. light (es)

A scanning movement device; 104. a condenser lens; 105. a controller;

DH. Compensating the thickness; D. a radius; d', width; E. ocular tissue; o, a central shaft; t1, target processing region; t2, target processing region; TE, sharp edge portion; TR, portion to be removed.

Detailed Description

In order to make the technical problems solved, technical solutions adopted and technical effects achieved by the present invention clearer, the technical solutions of the embodiments of the present invention will be further described in detail with reference to the accompanying drawings, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be obtained by a person skilled in the art without any inventive step based on the embodiments of the present invention, are within the scope of the present invention.

In the description of the present invention, unless otherwise expressly specified or limited, the terms "connected," "connected," and "fixed" are to be construed broadly, e.g., as meaning either a fixed connection, a removable connection, or an integral part; can be mechanically or electrically connected; either directly or indirectly through intervening media, either internally or in interactive relation with one another. The specific meanings of the above terms in the present invention can be understood in a specific case to those of ordinary skill in the art.

In the present invention, unless expressly stated or limited otherwise, the recitation of a first feature "on" or "under" a second feature may include the recitation of the first and second features being in direct contact, and may also include the recitation that the first and second features are not in direct contact, but are in contact via another feature between them. Also, the first feature being "on," "above" and "over" the second feature includes the first feature being directly on and obliquely above the second feature, or merely indicating that the first feature is at a higher level than the second feature. A first feature being "under," "below," and "beneath" a second feature includes the first feature being directly under and obliquely below the second feature, or simply meaning that the first feature is at a lesser elevation than the second feature.

The technical scheme of the invention is further explained by the specific implementation mode in combination with the attached drawings.

The present embodiment provides an ocular tissue treatment control method for controlling an ocular tissue treatment apparatus 100 to treat an ocular tissue E, which can treat and obtain a portion to be subsequently removed (taken out) from the ocular tissue E under the condition of maintaining the strength of the ocular tissue E, and the portion to be removed (taken out) has a characteristic of being not easily broken, so that the problems in the prior art can be overcome. In the following description of the embodiments of the present invention, the cornea is used as an example of the eye tissue E, but the present invention is not limited thereto, and the eye tissue E may be different eye tissues such as a crystal.

As shown in fig. 3a to 3b, a target treatment region T1 generated in an eye tissue E is exemplified by a target treatment region T1 including a sharp edge portion TE adjacent to a portion to be removed TR and a portion to be removed TR, the sharp edge portion TE including a thickness tapered portion having a tapered thickness with a minimum value of zero. Specifically, the sharp-edged portion TE is entirely a thickness-tapered portion, the thickness of which tapers from the portion to be removed TR adjacent thereto to a value of zero.

Specifically, as shown in fig. 3a and 3b, the target treatment region T1 generated in the eye tissue E includes: first, an inferior section 1 is generated in the eye tissue E by the femtosecond laser beam, then a sharp edge portion TE of the target treatment region T1 is ablated by the femtosecond laser beam, then a through section 3 intersecting the inferior section 1 is generated, and finally an superior section 2 connected to the inferior section 1 is generated in the eye tissue E by the femtosecond laser beam.

The through slice 3 penetrates the target processing region T1 from the upper slice 2 to the lower slice 1. After the target processing region T1 has undergone the above processing, the sharp-edged portion TE has been ablated by the femtosecond laser beam to become bubbled, leaving only the portion TR to be removed. Since the directivity of the laser is high, the femtosecond laser beam can ablate the sharp edge portion TE by applying the femtosecond laser beam densely at the sharp edge portion TE and ablating the sharp edge portion TE.

In addition, in order to remove the portion to be removed TR of the target treatment region T1 from the ocular tissue E, the target treatment region T1 further includes making a removal incision 4 in the ocular tissue E by the femtosecond laser beam, the removal incision 4 being located at the outer peripheral edge 21 of the upper section 2 and connected to the upper section 2 from the outer surface of the ocular tissue E, and the removal incision 4 being connected to the target treatment region T1 and communicating through the section 3. In other words, the portion TR to be removed of the target treatment region T1 in the eye tissue E may be removed by removing the incision 4.

As shown in fig. 3a and 3b, the upper cut surface 2 and the lower cut surface 1 generated by the femtosecond laser beam are connected to each other at the outer periphery 11 of the lower cut surface 1, and the sharp edge portion TE includes the interconnection of the upper cut surface 2 and the lower cut surface 1 at the outer periphery 11, at which time, the portion to be removed TR is located at the center of the target processing region T1, and the sharp edge portion TE is gradually reduced from the portion to be removed TR adjacent thereto toward the outer periphery 11 of the lower cut surface 1 and to a minimum thickness having a value of zero.

As shown in fig. 3a, 3b and 4, since the outer peripheral edge of the target processing region T1 corresponds to the outer peripheral edge 11 of the undercut surface 1, a radius D is formed between the central axis O and the outer peripheral edge of the target processing region T1, and the tangential plane 3 is a radial tangential plane extending from the outer peripheral edge 11 toward the central axis O along the radial direction by a width D', which is one third of the radius D.

It should be particularly noted that the through slice 3 is not limited to a radial slice as long as it penetrates the target processing region T1 from the upper slice 2 to the lower slice 1 and communicates with the removal notch 4, and the width D' of the through slice 3 is not limited to one third of the radius D of the target processing region T1 as long as the through slice 3 can have a certain thickness in the extending direction of the central axis O. The sharp-edged portion TE in the target processing region T1 shown in fig. 4 has been ablated by the femtosecond laser beam to be bubbled, and has a through cut surface 3 on the portion TR to be removed.

After cutting the target treatment region T1 from the eye tissue E using the femtosecond laser beam, as shown in fig. 5a, 5b, 5c, 6a, 6b, 6c, and 6d, since the sharp-edged portion TE has been ablated by the femtosecond laser beam and bubbled, the physician may perform a preliminary separation treatment on the portion to be removed TR using the separation instrument 5 before removing the portion to be removed TR.

The separator 5 includes a handle 51, and a short separator 52 and a long separator 53 are connected to both ends of the handle 51. Firstly, a handle part 51 and a short separating sheet 52 extend into a removing incision 4, the short separating sheet 52 extends into an upper incision surface 2 and a lower incision surface 1 of a target treatment area T1 from a penetrating incision surface 3, the two surfaces swing left and right respectively, a part TR to be removed is stripped from an eye tissue E to form a gap in a small range, namely the gap between the part TR to be removed and the eye tissue E, and then a separating tool 5 is pulled out from the removing incision 4; then, the handle 51 and the long separating piece 53 are inserted from the removing incision 4, and the long separating piece 53 is inserted into the upper incision 2 and the lower incision 1 of the target processing region T1 from the through incision 3, and then swung left and right, respectively, to peel the portion TR to be removed from the eye tissue E in a large range. It should be noted that the long separator 53 operates in the same manner as the short separator 52, and therefore the operation of the long separator 53 is not shown.

In this way, after the portion to be removed TR is previously separated from the eye tissue E by the positions of the upper incised plane 2 and the lower incised plane 1, the portion to be removed TR is finally taken out by clamping it with a removal jig, wherein the removal of the target treatment area T1 with the jig is a conventionally known means and thus is not shown in the figure.

Therefore, in the present invention, since the physician can use the separation tool 5 to extend the upper incision surface 2 and the lower incision surface 1 of the target treatment region T1 from the cut through surface 3 to separate the target treatment region T1 from the eye tissue E in advance from the upper incision surface 2 and the lower incision surface 1, the removal clip can clamp the target treatment region T1 and take it out, thereby effectively avoiding the problem of the target treatment region T1 being torn and broken due to the sticking to the eye tissue E during the clipping process. In this way, it can be seen that the portion TR to be removed taken out has a complete edge without being broken, when actually tested on the cornea of a pig eye.

After the portion TR to be removed of the target treatment region T1 is removed from the eye tissue E, the outer curvature of the eye tissue E is changed, for example, the outer curvature of the cornea becomes gentler in the present embodiment, thereby achieving the purpose of changing the curvature of the cornea to correct the vision. In other words, the target treatment area T1 shown in fig. 3a and 3b is an example of a target treatment area that needs to be removed from the cornea in order to correct myopia.

Fig. 7a and 7b show an example of another target treatment area T2 generated in eye tissue E in an embodiment of the present invention.

As shown in fig. 7a and 7b, a target treatment region T2 is generated in the eye tissue E in a manner similar to the target treatment region T1 shown in fig. 3a and 3b, the difference between which is that, in the example shown in fig. 7a and 7b, the lower cut surface 1 generated by the femtosecond laser beam first has a shape similar to "W", and the upper cut surface 2 and the lower cut surface 1 generated by the femtosecond laser beam are connected to each other at a portion near the central axis O of the eye tissue E in addition to the outer periphery 11 of the lower cut surface 1 (refer to fig. 7 b). The sharp-edged portion TE of the target processing region T2 thus includes the interconnection of the upper cut plane 2 and the lower cut plane 1 at the outer peripheral edge 11, and the interconnection of the upper cut plane 2 and the lower cut plane 1 at a portion near the central axis O. Furthermore, the sharp edge TE of the target processing region T2 also includes the turning points located at both sides of the "" W "" shaped lower section 1. These sharp edge portions TE of the target processing region T2 were bubbled by femtosecond laser beam ablation.

In addition, in order to remove the portion to be removed TR of the target treatment region T2 from the ocular tissue E, similar to the removal of the portion to be removed TR of the target treatment region T1 from the ocular tissue E described above, the embodiment of the present invention further includes making a through cut 3 and a removal incision 4 in the ocular tissue E by the femtosecond laser beam, the through cut 3 penetrates the target treatment region T2 from the upper cut 2 to the lower cut 1, the removal incision 4 is located at the outer periphery 21 of the upper cut 2 and is connected to the upper cut 2 from the outer surface of the ocular tissue E, and the removal incision 4 is also connected to the target treatment region T2 and penetrates through the cut 3. It is understood that the portion TR to be removed of the target treatment region T2 may be previously separated from the ocular tissue E at the upper and lower incised

planes

2 and 1 by extending through the cut plane 3 using the separation tool 5, and finally the portion TR to be removed is clamped by the removal jig and removed from the removal incision 4.

However, in the example shown in fig. 7a and 7b, since the upper cut plane 2 and the lower cut plane 1 of the target processing region T2 are connected to each other at a portion near the central axis O in addition to the outer peripheral edge 11 of the lower cut plane 1, the target processing region T2 has a doughnut-like shape when viewed from the direction of view as in fig. 7 a. In this case, if the portion TR to be removed of the target processing region T2 is to be removed through the removal incision 4, it is necessary to additionally ablate a cut surface 8 (see fig. 7a) in the eye tissue E by the femtosecond laser beam, one end of the cut surface 8 is connected to the outer peripheral edge 11, the other end of the cut surface 8 is connected to a portion close to the central axis O, and the cut surface 8 penetrates the target processing region T2 from the upper cut surface 2 to the lower cut surface 1, and further, the cut surface 8 is in a planar structure, and the cut surface 8 cuts both the upper cut surface 2 and the lower cut surface 1, so that the target processing region T2 is divided by the cut surface 8, and the portion TR to be removed of the target processing region T2 can be easily removed from the removal incision 4.

To further facilitate the removal of the portion to be removed TR of the target processing region T2 from the removal cut 4, it is preferable that the removal cut 4 is located on one side of the central axis O of the target processing region T2 and the cut surface 8 is located on one side of the central axis O of the target processing region T2 facing away from the removal cut 4, and specifically, the removal cut 4 and the cut surface 8 are respectively located on both sides of the central axis O of the target processing region T2, so that the portion to be removed TR of the target processing region T2 can be uniformly removed from the removal cut 4.

After the portion TR to be removed of the target treatment region T2 shown in fig. 7a and 7b is removed from the eye tissue E, the outer curvature of the eye tissue E is changed, i.e., the cornea in this embodiment becomes more raised, thereby achieving the purpose of changing the curvature of the cornea to correct the vision. In other words, the target treatment area T2 shown in fig. 7a and 7b is an example of a target treatment area that needs to be removed from the cornea in order to correct hyperopia.

In addition to the above-mentioned advantageous effect of facilitating the practitioner to separate target treatment region T1 from ocular tissue E at upper section 2 and lower section 1 in advance by providing through section 3 to avoid the problem of target treatment region T1 being torn during the clip grasping process by adhering to ocular tissue E by the separation instrument 5, as is clear from the above description of the examples of target treatment regions T1, T2 produced in ocular tissue E with reference to fig. 3a and 3b and fig. 7a and 7b for the embodiment of the present invention, since sharp-edged portion TE of target treatment region T1, sharp-edged portion TE of target treatment region T2 are ablated by the femtosecond laser beam before removing portion TR to be removed of target treatment region T1, portion TR to be removed of target treatment region T2, only portion TR to be removed of target treatment region T1 and portion TR to be removed of target treatment region T2 remain, and the part to be removed TR is previously separated from the ocular tissue E from the place of the upper incisal plane 2 and the lower incisal plane 1 by passing through the incisal plane 3, so that the part to be removed TR is less prone to rupture during the process of removing the target treatment area T1 and the target treatment area T2 of the ocular tissue E.

In addition, since the portion of the eye tissue E (e.g., cornea) to be removed is not cracked during the removal process, compared to the prior art in which the target treatment region is provided with an additional compensation thickness to avoid the cracking problem during the removal process, the present invention does not need to provide additional compensation thicknesses for the target treatment regions T1 and T2, so that the target treatment regions T1 and T2 have corresponding thicknesses according to the actual requirement of treating the eye tissue E, and the minimum value of the thicknesses may be zero. In other words, the present invention can avoid the additional increase of the thickness (e.g., the compensation thickness in the prior art) of the target treatment region T1 and the target treatment region T2, which is necessary for treating (e.g., correcting) the eye tissue E, thereby achieving the purpose of maintaining the strength of the eye tissue E to the maximum extent.

On the other hand, since the present invention can produce the target treatment regions T1, T2 with respective thicknesses without providing a compensation thickness, it can determine the ranges of the target treatment regions T1, T2 necessary for treating (e.g., correcting) the eye tissue E more accurately, so that the range that can be treated (e.g., the number of degrees of vision correctable) is wider. For example, for the correction of vision, if the maximum thickness of the removed target treatment region that the cornea can bear is DA, since the prior art must additionally set the compensation thickness DH for the removed target treatment region, the corrected vision range is within the range of the maximum thickness corresponding to DA-DH (the maximum thickness of the removed target treatment region that the cornea can bear minus the compensation thickness), in contrast, since the present invention does not need to set any compensation thickness, the corrected vision range is within the range of the maximum thickness corresponding to DA (the maximum thickness of the removed target treatment region T1 and the target treatment region T2 that the cornea can bear).

Fig. 8 is a schematic view of an ocular tissue treatment apparatus 100 according to an embodiment of the present invention.

As shown in fig. 8, the present embodiment provides an ocular tissue treatment device 100 including a laser light source 101 configured to generate a femtosecond laser beam; an optical system 102 configured to guide a femtosecond laser beam generated by the laser light source 101; an optical scanning movement device 103 configured to apply the femtosecond laser beam from the optical system 102 to the eye tissue E through a condenser lens 104; and a controller 105 connected to the laser light source 101, the optical system 102, and the optical scanning movement device 103, respectively, and configured to control the laser light source 101, the optical system 102, and the optical scanning movement device 103 to generate a target treatment region T1, a target treatment region T2 in the eye tissue E. The ocular tissue treatment apparatus 100 of the embodiment of the present invention further includes a removing device (e.g., the aforementioned separation instrument 5 and the clamp) configured to remove the portion to be removed TR of the target treatment region T1, T2 from the ocular tissue E under the operation of the user (see fig. 3a, 3b, 7a and 7 b).

Specifically, the controller 105 is configured to control the laser light source 101 to generate a femtosecond laser beam, the controller 105 can control the optical system 102 and guide the femtosecond laser beam to the optical scanning moving device 103, and the controller 105 can control the optical scanning moving device 103 to generate a target treatment region T1 and a target treatment region T2 in the eye tissue E by the femtosecond laser beam transmitted through the condenser 104, wherein the target treatment region T1 and the target treatment region T2 each include an upper section 2, a lower section 1 and a through section 3, and the through-section 3 passes through the target processing region T1 and the target processing region T2 from the upper section 2 to the lower section 1, and forms a sharp-edged portion TE, which may have a minimum thickness tapering to a value of zero, and the sharp-edged portion TE is ablated by densely applying the femtosecond laser beam during the generation of the target processing region T1, the target processing region T2.

For more details of how controller 105 generates target treatment regions T1, T2 in eye tissue E, reference may be made to the previous descriptions of fig. 3a, 3b, 7a, and 7b, which are not repeated here.

Similarly, in the ocular tissue treatment apparatus 100 of the present invention, since the controller 105 controls the optical scanning moving device 103 to generate the target treatment region T1 and the target treatment region T2 from the ocular tissue E by the femtosecond laser beam, the physician can first use the separation tool 5 to extend from the through section 3, and then use the flat short separation sheet 52 and the flat long separation sheet 53 of the separation tool 5 to separate the target treatment region T1 and the target treatment region T2 from the ocular tissue E at the upper section 2 and the lower section 1, so that the removal jig can clamp the target treatment region T1 and the target treatment region T2 to take them out, and the problem of the target treatment region T1 and the target treatment region T2 that are attached to the ocular tissue E and cause the tearing during the clamping process of the jig can be effectively avoided.

In addition, since the controller 105 controls the optical scanning moving device 103 to ablate the target treatment region T1 and the sharp-edged portion TE of the target treatment region T2 by the femtosecond laser beam before the removing device (for example, the aforementioned separating instrument 5 and jig) removes the target treatment region T1 and the portion TR to be removed of the target treatment region T2, so that only the portion TR to be removed remains in the target treatment region T1 and the target treatment region T2, and the portion TR to be removed is previously separated from the eye tissue E by the separating instrument 5 (refer to fig. 3a and 3b) from the upper tangent plane 2 and the lower tangent plane 1 through the tangent plane 3 before the portion TR to be removed is removed, so that the portion TR to be removed is less prone to fracture during the removing process. Therefore, the ocular tissue treatment apparatus 100 of the present invention can indeed effectively avoid the problem of the portions of the ocular tissue E (e.g., cornea) being removed (i.e., the target treatment regions T1, T2) breaking during the removal process.

Furthermore, since in the ocular tissue treatment apparatus 100 of the present invention, the portion of the ocular tissue E (e.g., cornea) to be removed does not crack during the removal process by the removal device, compared to the prior art in which the crack during the removal process is avoided by setting an additional compensation thickness for the target treatment region, the ocular tissue treatment apparatus 100 of the present invention does not need to set an additional compensation thickness for the target treatment regions T1, T2, so that, depending on the actual requirements of treating the ocular tissue E, the controller 105 of the ocular tissue treatment apparatus 100 of the present invention can control the optical scanning movement device 103 such that the resulting target treatment regions T1, T2 have corresponding thicknesses, and the minimum value of the thicknesses may be zero. In other words, the ocular tissue treatment apparatus 100 of the present invention can avoid the additional increase of the thickness (e.g., the compensation thickness in the prior art) of the target treatment region T1 and the target treatment region T2, which is necessary for treating (e.g., correcting) the ocular tissue E, thereby achieving the purpose of maintaining the strength of the ocular tissue E to the maximum extent.

On the other hand, also, since the ocular tissue treatment apparatus 100 according to the present invention can cause the resulting target treatment regions T1, T2 to have respective thicknesses without setting a compensation thickness, it can more accurately decide the ranges of the target treatment regions T1, T2 necessary for treating (e.g., correcting) the ocular tissue E, so that the range that it can treat (e.g., the correctable diopter) is wider.

Finally, the present embodiment also provides a readable medium for storing a computer program for executing the above-mentioned eye tissue processing control method, which can also achieve the beneficial effects as achieved by the above-mentioned eye tissue processing control method.

In the description herein, it is to be understood that the terms "upper," "lower," "right," and the like are based on the orientations and positional relationships shown in the drawings and are used for convenience in description and simplicity in operation, but do not indicate or imply that the referenced devices or elements must have a particular orientation, be constructed in a particular orientation, and be constructed in a particular manner of operation, and thus should not be construed as limiting the present invention. Furthermore, the terms "first" and "second" are used merely for descriptive purposes and are not intended to have any special meaning.

In the description herein, references to the description of "an embodiment," "an example" or the like mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the invention. In this specification, the schematic representations of the terms used above do not necessarily refer to the same embodiment or example.

In addition, the foregoing is only the preferred embodiment of the present invention and the technical principles applied. It will be understood by those skilled in the art that the present invention is not limited to the particular embodiments described herein, but is capable of various obvious changes, rearrangements and substitutions without departing from the scope of the invention. Therefore, although the present invention has been described in more detail by the above embodiments, the present invention is not limited to the above embodiments, and may include other equivalent embodiments without departing from the spirit of the present invention, and the scope of the present invention is determined by the scope of the appended claims.

Claims

1. An eye tissue treatment apparatus, comprising:

a laser light source configured to generate a femtosecond laser beam;

an optical scanning moving device configured to apply the femtosecond laser beam from the optical system to an eye tissue through a condenser lens;

controlling the laser light source to generate the femtosecond laser beam;

controlling the optical scanning movement device to generate a target treatment region in the eye tissue from the femtosecond laser beam, wherein the target treatment region comprises an upper section, a lower section and a through section, the through section penetrates the target treatment region from the upper section to the lower section, and controlling the optical scanning movement device to make a removal incision in the eye tissue from the femtosecond laser beam, the removal incision being connected to the target treatment region from an outer surface of the eye tissue and communicating with the through section.

2. The ocular tissue treatment device according to claim 1, further comprising:

3. The ocular tissue treatment device of claim 2, wherein the controller controlling the optical scanning movement apparatus to generate the target treatment region in the ocular tissue by the femtosecond laser beam comprises:

generating the lower section;

generating the through section intersecting the undercut plane; and

producing the upper tangent plane connected with the lower tangent plane.

4. The ocular tissue treatment apparatus of claim 2, wherein the target treatment region further comprises a portion to be removed and a sharp edge portion adjacent to the portion to be removed, the controller controlling the optical scanning movement device to ablate the sharp edge portion by the femtosecond laser beam such that the removal device is configured to remove the portion to be removed of the target treatment region from the ocular tissue.

5. The ocular tissue treatment device of claim 4, wherein the controller controlling the optical scanning movement apparatus to generate the target treatment region in the ocular tissue by the femtosecond laser beam comprises:

generating the through section intersecting the undercut plane; and

producing the upper tangent plane connected with the lower tangent plane.

6. The ocular tissue treatment device of claim 5, wherein the upper section and the lower section are interconnected at an outer periphery of the lower section; wherein, the first and the second end of the pipe are connected with each other,

the sharp edge portion includes a point where the upper cut surface and the lower cut surface are connected to each other at the outer peripheral edge so that the portion to be removed is located in the middle of the target treatment region.

7. The ocular tissue treatment device of claim 5, wherein the upper cut surface and the lower cut surface are connected to each other at an outer periphery and a central portion of the lower cut surface, respectively;

wherein said sharp edge portion includes an interconnection of said upper cut and said lower cut at said outer periphery and an interconnection of said upper cut and said lower cut at said central portion;

wherein the controller controls the optical scanning moving device to ablate and form a cutting plane in the target processing area by the femtosecond laser beam, one end of the cutting plane is connected to the outer peripheries of the upper section and the lower section, and the other end is connected to the central parts of the upper section and the lower section, so that the cutting plane penetrates through the target processing area from the upper section to the lower section.

8. The ocular tissue treatment device of claim 7, wherein the cut surface is planar in configuration, the cut surface extending through the target treatment area comprising: the cutting surface simultaneously cuts the upper section and the lower section;

9. The ocular tissue processing device of claim 4, wherein the sharp edge portion comprises a tapered thickness portion having a minimum tapered thickness of zero.

10. The ocular tissue treatment device of claim 1, wherein a radius is disposed between a central axis and an outer periphery of the target treatment region, the through cut is a radial cut extending in a radial direction from the outer periphery of the target treatment region toward the central axis of the target treatment region by a width of one third of the radius.

11. The ocular tissue treatment device according to any one of claims 1 to 10, wherein the ocular tissue is a cornea or a crystal.

12. An eye tissue processing control method for controlling an eye tissue processing apparatus, characterized by causing the eye tissue processing apparatus to execute:

generating a target treatment region in the eye tissue by using the femtosecond laser beam, wherein the target treatment region comprises an upper section, a lower section and a through section, and the through section penetrates through the target treatment region from the upper section to the lower section;

making a removal incision in the ocular tissue with the femtosecond laser beam, the removal incision connecting from an outer surface of the ocular tissue to the target treatment region and communicating with the through section; and

removing the target treatment area within the ocular tissue through the removal incision.

13. The ocular tissue treatment control method of claim 12, wherein generating the target treatment region in the ocular tissue by the femtosecond laser beam comprises:

generating the lower section;

generating the through section intersecting the undercut plane; and

producing the upper tangent plane connected with the lower tangent plane.

14. The ocular tissue treatment control method according to claim 12, wherein the target treatment region includes a portion to be removed and a sharp-edged portion adjacent to the portion to be removed;

during the generation of the target processing area, the sharp-edged portion is ablated by the femtosecond laser beam, and the portion to be removed of the target processing area is removed through the removal incision.

15. The ocular tissue treatment control method of claim 14, wherein generating the target treatment region in the ocular tissue by the femtosecond laser beam comprises:

creating the through facets that intersect the undercut facets; and

producing the upper tangent plane connected with the lower tangent plane.

16. The ocular tissue treatment control method of claim 15, wherein the upper cut plane and the lower cut plane are connected to each other at an outer periphery of the target treatment region;

17. The ocular tissue treatment control method of claim 15, wherein the upper cut plane and the lower cut plane are connected to each other at an outer periphery and a central portion of the target treatment region, respectively;

18. The method of controlling ocular tissue processing according to claim 17, wherein the cutting plane has a planar structure, and the cutting plane simultaneously cuts the upper section and the lower section;

19. The ocular tissue processing control method of claim 14, wherein the sharp edge portion comprises a tapered thickness portion, the tapered thickness of which has a minimum value of zero.

20. The method of controlling ocular tissue processing of claim 12, wherein a radius is provided between a central axis and an outer periphery of the target processing region, the through cut is a radial cut extending in a radial direction from the outer periphery of the target processing region toward the central axis of the target processing region by a width of one-third of the radius.

21. The method for controlling the treatment of an ocular tissue according to any one of claims 12 to 20, wherein the ocular tissue is a cornea or a crystal.

22. A readable medium storing a computer program for executing the method for controlling an eye tissue treatment according to any one of claims 12 to 21.